Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0287 | 0.0254 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.003 | 0.0362 | 0.1045 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.011 | 0.2963 | 0.3461 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0742 | 0.0842 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0287 | 0.0301 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0611 | 0.19 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.018 | 0.0145 |
Echinococcus multilocularis | geminin | 0.0171 | 0.4955 | 0.4939 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0186 | 0.543 | 0.5415 |
Schistosoma mansoni | survival motor neuron protein | 0.0055 | 0.1185 | 0.1296 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.0611 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0127 | 0.3535 | 0.3513 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.011 | 0.2963 | 1 |
Loa Loa (eye worm) | phosphofructokinase | 0.011 | 0.2963 | 0.3481 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.027 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0109 | 0.009 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0287 | 0.0254 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0338 | 0.0333 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0041 | 0.0742 | 0.0712 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.011 | 0.2963 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0041 | 0.0742 | 0.0842 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0738 | 0.0809 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.4955 | 0.5535 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0041 | 0.0742 | 0.0712 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0041 | 0.0738 | 0.0809 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0611 | 0.065 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.8153 | 0.9645 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.018 | 0.0145 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0738 | 0.0809 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0109 | 0.009 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.8452 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0022 | 0.0109 | 0.009 |
Brugia malayi | RNA binding protein | 0.0127 | 0.3535 | 0.416 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0899 | 0.0974 |
Echinococcus granulosus | geminin | 0.0171 | 0.4955 | 0.4939 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0279 | 0.8452 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0186 | 0.543 | 0.5415 |
Leishmania major | ATP-dependent phosphofructokinase | 0.011 | 0.2963 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0293 | 0.8925 | 1 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.011 | 0.2963 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0611 | 0.065 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0899 | 0.1029 |
Entamoeba histolytica | phosphofructokinase, putative | 0.011 | 0.2963 | 1 |
Brugia malayi | hypothetical protein | 0.027 | 0.8153 | 0.9645 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0287 | 0.0285 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.8452 | 1 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.003 | 0.0362 | 0.5 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.027 | 0.8153 | 0.8147 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0611 | 0.206 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0214 | 0.6359 | 0.7514 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.4955 | 0.5535 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0362 | 0.0362 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0255 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0109 | 0.009 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0634 | 0.0685 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0059 | 0.0029 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.011 | 0.2963 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0041 | 0.0742 | 0.0842 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0035 | 0.0551 | 0.1693 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0068 | 0.1601 | 0.1574 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0041 | 0.0742 | 0.0842 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0041 | 0.0742 | 0.0798 |
Schistosoma mansoni | 6-phosphofructokinase | 0.011 | 0.2963 | 0.3295 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0186 | 0.543 | 0.5415 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0193 | 0.5659 | 0.6672 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0041 | 0.0742 | 0.0842 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0045 | 0.0845 | 0.0815 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.8452 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0611 | 0.0657 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0022 | 0.0109 | 0.0076 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.8452 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0041 | 0.0742 | 0.0842 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0041 | 0.0742 | 0.0842 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0022 | 0.0109 | 0.0085 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.011 | 0.2963 | 1 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0611 | 0.0686 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0068 | 0.1601 | 0.1863 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0214 | 0.6359 | 0.7514 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0022 | 0.0109 | 0.0076 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.0845 | 0.0937 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0041 | 0.0742 | 0.0712 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.1601 | 0.1764 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0549 | 0.0585 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.011 | 0.2963 | 0.3461 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0279 | 0.8452 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0041 | 0.0742 | 0.0842 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0283 | 0.0772 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0475 | 0.0496 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0041 | 0.0742 | 0.0712 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0549 | 0.0585 |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.1905 | 0.2106 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.011 | 0.2963 | 0.3481 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0549 | 0.0585 |
Brugia malayi | nuclear receptor NHR-88 | 0.0041 | 0.0742 | 0.0842 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0045 | 0.0845 | 0.2708 |
Schistosoma mansoni | lamin | 0.0027 | 0.0287 | 0.0285 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0059 | 0.0026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0255 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0109 | 0.009 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.5339 | 0.6291 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0899 | 0.1029 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0899 | 0.0974 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0041 | 0.0742 | 0.0842 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.018 | 0.0145 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0028 | 0.0308 | 0.0327 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0287 | 0.0254 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0045 | 0.0845 | 0.2708 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0183 | 0.5339 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0263 | 0.0244 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0287 | 0.0301 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0041 | 0.0742 | 0.0842 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0283 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0742 | 0.0842 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0041 | 0.0742 | 0.0712 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0041 | 0.0742 | 0.0712 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0293 | 0.8925 | 0.8922 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0899 | 0.0869 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.4157 | 0.4637 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0041 | 0.0742 | 0.0712 |
Entamoeba histolytica | phosphofructokinase, putative | 0.011 | 0.2963 | 1 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.011 | 0.2963 | 0.294 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.003 | 0.0362 | 0.4471 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.1601 | 0.1764 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0068 | 0.1601 | 0.1863 |
Schistosoma mansoni | alpha-glucosidase | 0.016 | 0.4591 | 0.5125 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0033 | 0.0475 | 0.6126 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0041 | 0.0742 | 0.0842 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.011 | 0.2963 | 1 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0287 | 0.0254 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.011 | 0.2963 | 0.3461 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0263 | 0.0244 |
Brugia malayi | phosphofructokinase | 0.011 | 0.2963 | 0.3481 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0475 | 0.0496 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0611 | 0.0657 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.003 | 0.0362 | 0.4471 |
Schistosoma mansoni | hypothetical protein | 0.0252 | 0.7583 | 0.849 |
Brugia malayi | nuclear receptor RXR | 0.0022 | 0.0109 | 0.009 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.0484 | 0.1463 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0041 | 0.0742 | 0.0842 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0252 | 0.7583 | 0.7575 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0068 | 0.1601 | 0.1574 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0283 | 0.7388 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0068 | 0.1601 | 0.1574 |
Brugia malayi | Cytochrome P450 family protein | 0.0028 | 0.0308 | 0.0327 |
Brugia malayi | hypothetical protein | 0.0077 | 0.1905 | 0.2224 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.1601 | 0.1764 |
Onchocerca volvulus | 0.0107 | 0.2888 | 0.538 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0369 | 0.037 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0742 | 0.0842 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.8452 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.0845 | 0.0937 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0041 | 0.0742 | 0.0842 |
Loa Loa (eye worm) | TAR-binding protein | 0.0127 | 0.3535 | 0.416 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.003 | 0.0362 | 0.5 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.003 | 0.0362 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0041 | 0.0742 | 0.0798 |
Toxoplasma gondii | 6-phosphofructokinase | 0.003 | 0.0362 | 0.4471 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.5339 | 0.6291 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0041 | 0.0742 | 0.0842 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0041 | 0.0742 | 0.0842 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0287 | 0.0254 |
Brugia malayi | 6-phosphofructokinase | 0.011 | 0.2963 | 0.3481 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0041 | 0.0742 | 0.0798 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0146 | 0.4157 | 0.4898 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.003 | 0.0362 | 1 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0045 | 0.0845 | 0.2708 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0611 | 0.058 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1601 | 0.1863 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0041 | 0.0742 | 0.0842 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.003 | 0.0362 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0045 | 0.0845 | 0.0965 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0022 | 0.0109 | 0.0085 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0045 | 0.0845 | 0.0913 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0611 | 0.19 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.018 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0742 | 0.0842 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0738 | 0.0809 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0059 | 0.0026 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0041 | 0.0738 | 0.0809 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0186 | 0.543 | 0.6411 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0041 | 0.0742 | 0.0712 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0252 | 0.7583 | 0.7575 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.011 | 0.2963 | 0.3481 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.3535 | 0.3938 |
Echinococcus granulosus | 6 phosphofructokinase | 0.011 | 0.2963 | 0.294 |
Trypanosoma brucei | glucosidase, putative | 0.0041 | 0.0738 | 0.249 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0549 | 0.0585 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0041 | 0.0742 | 0.0712 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0738 | 0.2338 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0041 | 0.0742 | 0.0842 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.3535 | 0.3938 |
Giardia lamblia | GTOR | 0.0045 | 0.0845 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0077 | 0.1905 | 0.1879 |
Brugia malayi | nuclear hormone receptor | 0.0041 | 0.0742 | 0.0842 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0041 | 0.0742 | 0.0842 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0041 | 0.0742 | 0.0798 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.5339 | 0.6291 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.003 | 0.0362 | 0.3861 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0362 | 0.0362 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0035 | 0.0551 | 0.1693 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.3535 | 0.3938 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0283 | 0.0955 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0041 | 0.0742 | 0.0842 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.3535 | 0.3938 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0362 | 0.0362 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0738 | 0.0809 |
Echinococcus multilocularis | tar DNA binding protein | 0.0127 | 0.3535 | 0.3513 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.5339 | 0.6291 |
Schistosoma mansoni | coup transcription factor | 0.0041 | 0.0742 | 0.0798 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.0611 | 0.19 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0742 | 0.0842 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0951 | 0.1091 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0899 | 0.0974 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0035 | 0.0551 | 0.1858 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0899 | 0.0869 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.003 | 0.0362 | 0.0362 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0899 | 0.0869 |
Brugia malayi | ecdysteroid receptor | 0.0041 | 0.0742 | 0.0842 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0109 | 0.009 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0475 | 0.0496 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 0.6359 | 0.7514 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0742 | 0.0842 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0475 | 0.0496 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0045 | 0.0845 | 0.2708 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0055 | 0.1185 | 0.1368 |
Brugia malayi | MH2 domain containing protein | 0.012 | 0.3295 | 0.3875 |
Onchocerca volvulus | 0.0041 | 0.0742 | 0.1337 | |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0041 | 0.0738 | 0.0809 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0041 | 0.0742 | 0.0842 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0179 | 0.0143 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0179 | 0.0143 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0738 | 0.2338 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0263 | 0.0244 |
Schistosoma mansoni | alpha glucosidase | 0.0041 | 0.0738 | 0.0793 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0742 | 0.0842 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.8452 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0293 | 0.8925 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0041 | 0.0742 | 0.0712 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0059 | 0.0029 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0475 | 0.0496 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.1905 | 0.6358 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0021 | 0.0083 | 0.0281 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.003 | 0.0362 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0068 | 0.1601 | 0.1863 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0899 | 0.0869 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0041 | 0.0738 | 0.0837 |
Entamoeba histolytica | phosphofructokinase, putative | 0.011 | 0.2963 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0611 | 0.8126 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0283 | 0.0297 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0475 | 0.0496 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0041 | 0.0742 | 0.0798 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0611 | 0.0657 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0287 | 0.0301 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.012 | 0.3295 | 0.3875 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0059 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0109 | 0.009 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0041 | 0.0742 | 0.0842 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0738 | 0.0809 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.027 | 0.8153 | 0.8147 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0742 | 0.0842 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0041 | 0.0738 | 0.0707 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0362 | 0.0362 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0611 | 0.19 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0041 | 0.0742 | 0.0842 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0077 | 0.1905 | 0.1879 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0045 | 0.0845 | 0.2708 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0951 | 0.1033 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0045 | 0.0845 | 0.0965 |
Brugia malayi | TAR-binding protein | 0.0127 | 0.3535 | 0.416 |
Loa Loa (eye worm) | RNA binding protein | 0.0127 | 0.3535 | 0.416 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0127 | 0.3535 | 0.416 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0109 | 0.009 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0041 | 0.0742 | 0.0798 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0193 | 0.5659 | 0.6672 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0077 | 0.1905 | 0.2106 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0041 | 0.0742 | 0.0842 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0041 | 0.0738 | 0.2338 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0109 | 0.009 |
Onchocerca volvulus | 0.0027 | 0.0287 | 0.0478 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0041 | 0.0742 | 0.0842 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0287 | 0.0301 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0214 | 0.6359 | 0.7514 |
Brugia malayi | steroid hormone receptor | 0.0041 | 0.0742 | 0.0842 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0549 | 0.0585 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0127 | 0.3535 | 0.416 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0041 | 0.0742 | 0.0712 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0045 | 0.0845 | 0.2852 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0041 | 0.0742 | 0.0712 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.5339 | 0.6291 |
Echinococcus granulosus | FTZ F1 alpha | 0.0041 | 0.0742 | 0.0712 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0041 | 0.0738 | 0.2338 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.1905 | 0.6358 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.1601 | 0.1764 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.012 | 0.3295 | 0.3875 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0059 | 0.0031 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0041 | 0.0742 | 0.0712 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0287 | 0.0301 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0179 | 0.0143 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0362 | 0.0362 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0041 | 0.0738 | 1 |
Schistosoma mansoni | lamin | 0.0027 | 0.0287 | 0.0285 |
Schistosoma mansoni | alpha-glucosidase | 0.016 | 0.4591 | 0.5125 |
Echinococcus granulosus | GPCR family 2 | 0.0068 | 0.1601 | 0.1574 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0041 | 0.0738 | 0.2338 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0109 | 0.009 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0362 | 0.0362 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0475 | 0.0496 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0045 | 0.0845 | 0.2708 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0283 | 0.0772 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0186 | 0.543 | 0.6411 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0041 | 0.0742 | 0.0712 |
Schistosoma mansoni | 6-phosphofructokinase | 0.011 | 0.2963 | 0.3295 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.0845 | 0.0937 |
Echinococcus multilocularis | tumor protein p63 | 0.0326 | 1 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0611 | 0.058 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.4157 | 0.4898 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0045 | 0.0845 | 0.0815 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0041 | 0.0742 | 0.0842 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.5339 | 0.6291 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.011 | 0.2963 | 0.3461 |
Brugia malayi | 6-phosphofructokinase | 0.011 | 0.2963 | 0.3481 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0041 | 0.0742 | 0.0712 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0041 | 0.0738 | 0.0707 |
Onchocerca volvulus | 0.0055 | 0.1185 | 0.2171 | |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0611 | 0.19 |
Echinococcus granulosus | lamin | 0.0027 | 0.0287 | 0.0254 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0041 | 0.0742 | 0.0798 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.1905 | 0.6358 |
Schistosoma mansoni | nuclear hormone receptor | 0.0041 | 0.0742 | 0.0798 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0045 | 0.0845 | 0.2852 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0068 | 0.1601 | 0.1574 |
Onchocerca volvulus | 0.0048 | 0.0951 | 0.1731 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0041 | 0.0742 | 0.0798 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0041 | 0.0742 | 0.0712 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0059 | 0.0031 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.003 | 0.0362 | 0.1045 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0041 | 0.0742 | 0.1337 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0041 | 0.0742 | 0.1337 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0041 | 0.0742 | 0.1337 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0041 | 0.0738 | 0.0809 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0611 | 0.0686 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0041 | 0.0738 | 0.0837 |
Echinococcus multilocularis | GPCR, family 2 | 0.0068 | 0.1601 | 0.1574 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0283 | 0.3303 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0283 | 0.7388 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.3535 | 0.3938 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.1185 | 0.1296 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.1905 | 0.6358 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0283 | 0.7388 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.5339 | 0.6291 |
Onchocerca volvulus | 0.0027 | 0.0287 | 0.0478 | |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0283 | 0.0772 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0041 | 0.0742 | 0.0798 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | < 10 % | Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as inhibition of NO production at 20 uM after 20 hrs relative to control | ChEMBL. | 19394216 |
Inhibition (functional) | = 23 % | Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as inhibition of NO production at 50 uM after 20 hrs relative to control | ChEMBL. | 19394216 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.