Detailed information for compound 957847

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 508.56 | Formula: C29H32O8
  • H donors: 0 H acceptors: 4 LogP: 4.17 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)[C@@H]1C[C@H](OC(=O)C)C(=O)[C@H]2[C@@]1(C)CC[C@@H]1[C@]2(C)C[C@H](OC1=O)c1ccoc1c1ccccc1
  • InChi: 1S/C29H32O8/c1-16(30)36-21-14-20(26(32)34-4)28(2)12-10-19-27(33)37-22(15-29(19,3)25(28)23(21)31)18-11-13-35-24(18)17-8-6-5-7-9-17/h5-9,11,13,19-22,25H,10,12,14-15H2,1-4H3/t19-,20-,21-,22-,25-,28-,29-/m0/s1
  • InChiKey: KJGYTGJKTVVSGO-MGRBCCQOSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens opioid receptor, kappa 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Echinococcus multilocularis valyl tRNA synthetase 0.0022 0.0054 0.0039
Schistosoma mansoni hypothetical protein 0.0019 0.0038 0.0023
Mycobacterium tuberculosis Probable valyl-tRNA synthase protein ValS (valyl-tRNA synthetase) (valine--tRNA ligase) (valine translase) 0.0022 0.0054 0.0063
Echinococcus granulosus isoleucyl tRNA synthetase, cytoplasmic 0.0061 0.0298 0.0284
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0021 0.0048 0.1612
Echinococcus granulosus lamin 0.0033 0.0122 0.0107
Loa Loa (eye worm) hypothetical protein 0.0044 0.0189 0.1081
Toxoplasma gondii leucyl-tRNA synthetase (LeuRS2) 0.0022 0.0054 0.0149
Chlamydia trachomatis threonine--tRNA ligase 0.0054 0.0253 0.1311
Echinococcus multilocularis musashi 0.0033 0.0122 0.0107
Toxoplasma gondii tRNA binding domain-containing protein 0.0015 0.0015 0.004
Toxoplasma gondii isoleucyl-tRNA synthetase, putative 0.0022 0.0054 0.0149
Brugia malayi protein ZK524.3 0.0056 0.0265 0.1421
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.0019 0.0039 0.0045
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0054 0.0253 0.8486
Giardia lamblia Cysteinyl-tRNA synthetase 0.0019 0.0039 0.0853
Loa Loa (eye worm) methionyl-tRNA synthetase 0.0047 0.0211 0.1205
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0038 0.0023
Echinococcus granulosus isoleucyl trna synthetase mitochondrial 0.0048 0.0217 0.0203
Mycobacterium leprae isoleucyl-tRNA synthetase IleS 0.0061 0.0298 0.0364
Leishmania major threonyl-tRNA synthetase, putative 0.0054 0.0253 0.7119
Echinococcus multilocularis dnaJ subfamily B 0.0472 0.2829 0.2818
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0038 0.0377
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0175 0.0934
Brugia malayi beta-lactamase 0.0044 0.0189 0.1012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0033 0.0123 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Loa Loa (eye worm) hypothetical protein 0.0044 0.0189 0.1081
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0384
Entamoeba histolytica leucyl-tRNA synthetase, putative 0.0022 0.0054 0.0276
Echinococcus multilocularis geminin 0.0206 0.1189 0.1176
Trypanosoma cruzi valyl-tRNA synthetase, putative 0.0022 0.0054 0.18
Mycobacterium leprae PROBABLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA3 0.0019 0.004 0.0045
Brugia malayi Calcitonin receptor-like protein seb-1 0.0061 0.0293 0.1575
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0038 0.0023
Schistosoma mansoni lipoxygenase 0.0067 0.0333 0.0319
Loa Loa (eye worm) hypothetical protein 0.0297 0.175 1
Trypanosoma cruzi tyrosyl or methionyl-tRNA synthetase, putative 0.0015 0.0015 0.0495
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0017 0.0002
Loa Loa (eye worm) hypothetical protein 0.0056 0.0265 0.1512
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0312 0.1846 1
Echinococcus granulosus cpg binding protein 0.0035 0.0135 0.0121
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0019 0.0039 0.1306
Trypanosoma brucei valyl-tRNA synthetase, putative 0.0022 0.0054 0.1793
Mycobacterium tuberculosis Isoleucyl-tRNA synthetase IleS 0.004 0.0164 0.0199
Schistosoma mansoni cpg binding protein 0.0035 0.0135 0.0121
Trichomonas vaginalis methionyl-tRNA synthetase, putative 0.0015 0.0015 0.0495
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0048 0.0275
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.007 0.0349 1
Wolbachia endosymbiont of Brugia malayi cysteinyl-tRNA synthetase 0.0019 0.0039 0.0508
Leishmania major phosphatidylinositol kinase related protein, putative 0.0021 0.0048 0.1002
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0038 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Echinococcus granulosus lamin dm0 0.0033 0.0122 0.0107
Schistosoma mansoni methionine-tRNA synthetase 0.0047 0.0211 0.0196
Schistosoma mansoni lamin 0.0033 0.0122 0.0107
Leishmania major methionyl-tRNA synthetase, putative 0.0047 0.0211 0.5864
Leishmania major valyl-tRNA synthetase, putative 0.0022 0.0054 0.1162
Schistosoma mansoni methionine-tRNA synthetase 0.031 0.1831 0.1819
Loa Loa (eye worm) hypothetical protein 0.0025 0.0071 0.0408
Trypanosoma brucei tyrosyl-tRNA synthetase, putative 0.0015 0.0015 0.0487
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Loa Loa (eye worm) hypothetical protein 0.0041 0.0175 0.0999
Schistosoma mansoni methyltransferase-related 0.0023 0.0061 0.0046
Mycobacterium tuberculosis Possible penicillin-binding protein 0.028 0.1643 0.2022
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0061 0.0293 0.1674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0033 0.0123 0.0148
Brugia malayi AMP-binding enzyme family protein 0.0033 0.0123 0.0652
Schistosoma mansoni cpg binding protein 0.0033 0.0124 0.0109
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0021 0.0048 0.1605
Plasmodium falciparum valine--tRNA ligase, putative 0.0022 0.0054 0.0637
Schistosoma mansoni hypothetical protein 0.0019 0.0038 0.0023
Mycobacterium tuberculosis Conserved protein 0.0044 0.0189 0.023
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.007 0.0349 0.0427
Loa Loa (eye worm) hypothetical protein 0.0044 0.0189 0.1081
Mycobacterium tuberculosis Probable hydrolase 0.0044 0.0189 0.023
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0048 0.0275
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0122 0.0645
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0076
Loa Loa (eye worm) glycyl-tRNA synthetase 0.017 0.0964 0.551
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0033 0.0123 0.0148
Trichomonas vaginalis D-aminoacylase, putative 0.0044 0.0189 0.6349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Wolbachia endosymbiont of Brugia malayi leucyl-tRNA synthetase 0.0069 0.0345 0.6936
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0021 0.0048 0.0033
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0033 0.0123 0.0148
Toxoplasma gondii tRNA synthetase, putative 0.0022 0.0054 0.0149
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0044 0.0189 0.023
Toxoplasma gondii methionyl-tRNA synthetase 0.0063 0.0306 0.0852
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0067 0.0858
Mycobacterium ulcerans isoleucyl-tRNA synthetase 0.0061 0.0298 0.0364
Plasmodium falciparum methionine--tRNA ligase 0.0047 0.0211 0.3213
Mycobacterium tuberculosis Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.0596 0.3595 0.4427
Onchocerca volvulus 0.0033 0.0124 0.1176
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0067 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.1035 0.6299 0.7759
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0122 0.0694
Mycobacterium ulcerans thioesterase 0.0321 0.1899 0.2338
Mycobacterium leprae Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA GLYCOSYLASE) 0.0093 0.0491 0.0602
Plasmodium falciparum threonine--tRNA ligase 0.0048 0.0213 0.3253
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0048 0.0213 0.026
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0048 0.162
Echinococcus multilocularis methionyl tRNA synthetase, cytoplasmic 0.031 0.1831 0.1819
Schistosoma mansoni lipoxygenase 0.0024 0.0067 0.0052
Mycobacterium tuberculosis Probable lipase LipE 0.0044 0.0189 0.023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0217 0.1242
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0038 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Schistosoma mansoni leucyl-tRNA synthetase 0.0069 0.0345 0.0331
Plasmodium falciparum isoleucine--tRNA ligase, putative 0.0115 0.0625 1
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0021 0.0048 0.1605
Echinococcus granulosus methionyl tRNA synthetase cytoplasmic 0.031 0.1831 0.1819
Mycobacterium ulcerans hypothetical protein 0.0044 0.0189 0.023
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0076
Echinococcus granulosus leucyl tRNA synthetase 0.0041 0.0173 0.0159
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0038 0.0216
Chlamydia trachomatis leucine--tRNA ligase 0.006 0.0292 0.1524
Schistosoma mansoni hypothetical protein 0.0206 0.1189 0.1176
Mycobacterium ulcerans pantoate--beta-alanine ligase 0.0596 0.3595 0.4427
Entamoeba histolytica cysteinyl-tRNA synthetase, putative 0.0019 0.0039 0.0197
Trypanosoma cruzi tyrosyl or methionyl-tRNA synthetase, putative 0.0015 0.0015 0.0495
Onchocerca volvulus 0.0033 0.0122 0.1155
Mycobacterium ulcerans valyl-tRNA synthetase 0.0022 0.0054 0.0063
Onchocerca volvulus 0.0033 0.0123 0.1168
Loa Loa (eye worm) hypothetical protein 0.0061 0.0298 0.1703
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0189 0.6349
Giardia lamblia Methyltransferase like 2 0.0023 0.0061 0.1631
Trichomonas vaginalis penicillin-binding protein, putative 0.0044 0.0189 0.6349
Echinococcus multilocularis RUN 0.0024 0.0067 0.0052
Leishmania major isoleucyl-tRNA synthetase, putative 0.0061 0.0298 0.8467
Loa Loa (eye worm) multisynthetase complex auxiliary component p43 0.0265 0.1554 0.8879
Mycobacterium tuberculosis Possible DNA glycosylase 0.0093 0.0491 0.0602
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0353 0.0338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0038 0.0023
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0048 0.1612
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0021 0.0048 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0015 0.0495
Plasmodium falciparum cysteine--tRNA ligase 0.0019 0.0039 0.0396
Schistosoma mansoni hypothetical protein 0.0206 0.1189 0.1176
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0021 0.0048 0.1605
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0384
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0071 0.2394
Trypanosoma cruzi target of rapamycin kinase 3 0.0021 0.0048 0.1612
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0054 0.0253 0.8485
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0038 0.0698
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, beta chain PheT 0.0015 0.0015 0.0015
Onchocerca volvulus 0.0044 0.0189 0.1799
Mycobacterium tuberculosis Hypothetical protein 0.0023 0.0061 0.0072
Onchocerca volvulus 0.0184 0.1052 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0108 0.0588 0.0574
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0029 0.0096 0.3224
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0021 0.0048 0.1605
Schistosoma mansoni isoleucine--tRNA ligase 0.0061 0.0298 0.0284
Toxoplasma gondii pantoate-beta-alanine ligase 0.0596 0.3595 1
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0038 0.0105
Plasmodium vivax methionine--tRNA ligase, putative 0.0047 0.0211 0.5938
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0044 0.0189 0.1012
Onchocerca volvulus 0.0033 0.0122 0.1155
Brugia malayi hypothetical protein 0.0024 0.0067 0.035
Schistosoma mansoni threonyl-tRNA synthetase 0.0043 0.0185 0.0171
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0067 0.0333 0.0319
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0021 0.0048 0.1605
Wolbachia endosymbiont of Brugia malayi formamidopyrimidine-DNA glycosylase 0.0093 0.0491 1
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0054 0.0253 0.1358
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0044 0.0189 0.1081
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.007 0.0349 0.0335
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0108 0.0588 0.0574
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0048 0.0246
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0044 0.0189 0.0175
Schistosoma mansoni hypothetical protein 0.0041 0.0175 0.016
Plasmodium vivax hypothetical protein, conserved 0.0069 0.0345 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0038 0.1261
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0027 0.0087 0.0104
Entamoeba histolytica hypothetical protein 0.0015 0.0015 0.0065
Mycobacterium leprae Probable pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.0596 0.3595 0.4427
Plasmodium vivax cysteine--tRNA ligase, putative 0.0019 0.0039 0.0732
Leishmania major cysteinyl-tRNA synthetase, putative 0.0019 0.0039 0.0723
Giardia lamblia Methionyl-tRNA synthetase 0.0047 0.0211 0.6925
Echinococcus multilocularis leucyl tRNA synthetase 0.0022 0.0054 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0054 0.0253 0.1445
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0354 0.2103 0.2588
Loa Loa (eye worm) hypothetical protein 0.0044 0.0189 0.1081
Echinococcus multilocularis isoleucyl tRNA synthetase, mitochondrial 0.0048 0.0217 0.0203
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0038 0.0023
Plasmodium falciparum valine--tRNA ligase, putative 0.0022 0.0054 0.0637
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0015 0.0495
Plasmodium vivax isoleucine--tRNA ligase, putative 0.0061 0.0298 0.8574
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0027 0.0087 0.0104
Treponema pallidum leucyl-tRNA synthetase 0.006 0.0292 0.1398
Mycobacterium tuberculosis Conserved protein 0.0044 0.0189 0.023
Onchocerca volvulus 0.0024 0.0067 0.0639
Schistosoma mansoni valine-tRNA ligase 0.0022 0.0054 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Leishmania major hypothetical protein, conserved 0.0023 0.0061 0.1381
Echinococcus multilocularis beta LACTamase domain containing family member 0.0044 0.0189 0.0175
Mycobacterium tuberculosis Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) 0.0047 0.0211 0.0257
Echinococcus granulosus Threonyl tRNA synthetase C 0.0054 0.0253 0.0239
Schistosoma mansoni isoleucine--tRNA ligase 0.0061 0.0298 0.0284
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0038 0.0023
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0021 0.0048 0.0995
Echinococcus multilocularis isoleucyl tRNA synthetase, cytoplasmic 0.0061 0.0298 0.0284
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0038 0.0189
Echinococcus multilocularis microtubule associated protein 2 0.1635 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0306 0.0852
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.032 0.1831
Treponema pallidum isoleucyl-tRNA synthetase 0.0061 0.0298 0.1434
Mycobacterium tuberculosis Conserved protein 0.0044 0.0189 0.023
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0038 0.1269
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0015 0.0495
Loa Loa (eye worm) hypothetical protein 0.0184 0.1052 0.601
Echinococcus granulosus dnaJ subfamily B 0.0472 0.2829 0.2818
Brugia malayi valyl-tRNA synthetase family protein 0.0022 0.0054 0.0276
Brugia malayi isoleucyl-tRNA synthetase 0.0061 0.0298 0.1603
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.007 0.0349 0.1881
Schistosoma mansoni lamin 0.0033 0.0122 0.0107
Chlamydia trachomatis methionine--tRNA ligase 0.031 0.1831 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0092 0.0526
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0124 0.0707
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0048 0.1612
Schistosoma mansoni polycystin 1-related 0.0024 0.0067 0.0052
Brugia malayi hypothetical protein 0.0184 0.1052 0.5693
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Brugia malayi methionyl-tRNA synthetase 0.0047 0.0211 0.113
Echinococcus multilocularis cpg binding protein 0.0035 0.0135 0.0121
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit beta 0.0015 0.0015 0.0015
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.133 0.8117 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0015 0.0495
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0038 0.0105
Loa Loa (eye worm) hypothetical protein 0.0022 0.0054 0.0306
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0158 0.0893 0.5105
Brugia malayi cytoplasmic intermediate filament protein 0.0018 0.0028 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0017 0.0002
Echinococcus granulosus valyl tRNA synthetase 0.0022 0.0054 0.0039
Echinococcus granulosus serine protein kinase ATM 0.0029 0.0096 0.0081
Giardia lamblia Valine-tRNA ligase 0.0022 0.0054 0.1372
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0021 0.0048 0.0995
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0019 0.0039 0.0024
Giardia lamblia GTOR 0.0021 0.0048 0.1175
Plasmodium falciparum leucine--tRNA ligase, putative 0.0022 0.0054 0.0637
Brugia malayi isoleucyl-tRNA synthetase family protein 0.0061 0.0298 0.1603
Mycobacterium ulcerans esterase/lipase LipP 0.0044 0.0189 0.023
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.017 0.0964 0.5218
Echinococcus granulosus valyl tRNA synthetase 0.0022 0.0054 0.0039
Onchocerca volvulus 0.0033 0.0123 0.1168
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.007 0.0349 0.0427
Mycobacterium ulcerans formamidopyrimidine-DNA glycosylase 0.0093 0.0491 0.0602
Loa Loa (eye worm) beta-lactamase 0.0044 0.0189 0.1081
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0038 0.0215
Wolbachia endosymbiont of Brugia malayi isoleucyl-tRNA synthetase 0.0061 0.0298 0.5947
Brugia malayi beta-lactamase family protein 0.0044 0.0189 0.1012
Echinococcus multilocularis methionine tRNA synthetase 0.0047 0.0211 0.0196
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0048 0.0213 0.026
Schistosoma mansoni hypothetical protein 0.0019 0.0038 0.0023
Toxoplasma gondii cysteine-tRNA synthetase (CysRS) 0.0019 0.0039 0.0108
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0038 0.0023
Schistosoma mansoni loxhd1 0.0024 0.0067 0.0052
Chlamydia trachomatis valine--tRNA ligase 0.0022 0.0054 0.0214
Entamoeba histolytica hypothetical protein 0.0029 0.0096 0.0507
Trypanosoma brucei isoleucyl-tRNA synthetase, putative 0.0061 0.0298 1
Toxoplasma gondii leucyl-tRNA synthetase 0.0022 0.0054 0.0149
Toxoplasma gondii FATC domain-containing protein 0.0029 0.0096 0.0267
Echinococcus multilocularis serine protein kinase ATM 0.0029 0.0096 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0015 0.0495
Trypanosoma brucei methionyl-tRNA synthetase, putative 0.0047 0.0211 0.7075
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0038 0.1269
Trichomonas vaginalis methionine-tRNA synthetase, putative 0.0047 0.0211 0.7077
Mycobacterium tuberculosis Possible conserved polyketide synthase associated protein PapA2 0.0019 0.004 0.0045
Toxoplasma gondii isoleucyl-tRNA synthetase family protein 0.0061 0.0298 0.0829
Echinococcus multilocularis GPCR, family 2 0.0019 0.0038 0.0023
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0048 0.0213 0.4169
Echinococcus granulosus methionine tRNA synthetase 0.0047 0.0211 0.0196
Plasmodium falciparum isoleucine--tRNA ligase, putative 0.0061 0.0298 0.464
Trichomonas vaginalis isoleucyl tRNA synthetase, putative 0.0061 0.0298 1
Brugia malayi cysteinyl tRNA synthetase protein 1 0.0019 0.0039 0.0197
Trichomonas vaginalis leucyl-tRNA synthetase, putative 0.0022 0.0054 0.18
Schistosoma mansoni valine-tRNA ligase 0.0022 0.0054 0.0039
Loa Loa (eye worm) hypothetical protein 0.0061 0.0293 0.1674
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0189 0.6349
Brugia malayi beta-lactamase family protein 0.0044 0.0189 0.1012
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0038 0.0689
Giardia lamblia Isoleucyl-tRNA synthetase 0.0061 0.0298 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0108 0.0588 0.0574
Echinococcus multilocularis lamin 0.0033 0.0122 0.0107
Schistosoma mansoni intermediate filament proteins 0.0033 0.0122 0.0107
Trichomonas vaginalis leucyl-tRNA synthetase, putative 0.0022 0.0054 0.18
Toxoplasma gondii valyl-tRNA synthetase 0.0022 0.0054 0.0149
Brugia malayi methionyl-tRNA synthetase 0.0312 0.1846 1
Brugia malayi hypothetical protein 0.0024 0.0067 0.035
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0029 0.0096 0.0507
Brugia malayi glycyl-tRNA synthetase 0.017 0.0964 0.5218
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0067 0.0384
Echinococcus granulosus RUN 0.0024 0.0067 0.0052
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0048 0.0213 0.1143
Plasmodium vivax valine--tRNA ligase, putative 0.0022 0.0054 0.1176
Mycobacterium ulcerans formamidopyrimidine-DNA glycosylase 0.0093 0.0491 0.0602
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0038 0.0043
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0108 0.0588 0.3174
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0021 0.0048 0.1612
Trypanosoma cruzi leucyl-tRNA synthetase, putative 0.0022 0.0054 0.18
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0038 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Schistosoma mansoni cpg binding protein 0.0035 0.0135 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0038 0.0023
Mycobacterium ulcerans lipase LipD 0.0044 0.0189 0.023
Giardia lamblia Threonyl-tRNA synthetase 0.0048 0.0213 0.7011
Mycobacterium leprae PROBABLE VALYL-tRNA SYNTHASE PROTEIN VALS (VALYL-tRNA SYNTHETASE) (VALINE--tRNA LIGASE) (VALINE TRANSLASE) ELONGS TO CLASS-I AMI 0.0022 0.0054 0.0063
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0108 0.0588 0.3357
Trichomonas vaginalis D-aminoacylase, putative 0.0044 0.0189 0.6349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Treponema pallidum threonyl-tRNA synthetase 0.0048 0.0213 0.0966
Leishmania major phosphatidylinositol 3-kinase, putative 0.0021 0.0048 0.0995
Echinococcus granulosus leucyl tRNA synthetase 0.0022 0.0054 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0061 0.2046
Echinococcus granulosus geminin 0.0206 0.1189 0.1176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Treponema pallidum methionyl-tRNA synthetase 0.0312 0.1846 1
Plasmodium vivax threonine--tRNA ligase, putative 0.0048 0.0213 0.6011
Onchocerca volvulus 0.0048 0.0217 0.2067
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.007 0.0349 0.0335
Mycobacterium leprae conserved hypothetical protein 0.0044 0.0189 0.023
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0021 0.0048 0.0033
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0038 0.0023
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0054 0.0253 0.0239
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.007 0.0349 0.0335
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0033 0.0123 0.0148
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.007 0.0349 0.0427
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Echinococcus granulosus cysteinyl tRNA synthetase 0.0019 0.0039 0.0024
Onchocerca volvulus 0.0044 0.0189 0.1799
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0029 0.0096 0.3219
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0038 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0122 0.0694
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0044 0.0189 0.023
Trichomonas vaginalis cysteinyl-tRNA synthetase, putative 0.0019 0.0039 0.1306
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0021 0.0048 0.0033
Loa Loa (eye worm) hypothetical protein 0.0044 0.0189 0.1081
Loa Loa (eye worm) hypothetical protein 0.006 0.0292 0.1666
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0021 0.0048 0.0033
Entamoeba histolytica valyl tRNA synthetase, putative 0.0022 0.0054 0.0276
Trypanosoma cruzi methionyl-tRNA synthetase, putative 0.0047 0.0211 0.7077
Schistosoma mansoni rab6-interacting 0.0024 0.0067 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0081 0.2729
Plasmodium falciparum methionine--tRNA ligase, putative 0.0047 0.0211 0.3213
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0044 0.0189 0.0175
Mycobacterium tuberculosis Probable lipase LipD 0.0044 0.0189 0.023
Mycobacterium tuberculosis Conserved polyketide synthase associated protein PapA1 0.0019 0.004 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0 0.0008
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0067 0.0052
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0067 0.0052
Brugia malayi CXXC zinc finger family protein 0.0033 0.0124 0.0656
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0189 0.6346
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0108 0.0588 0.0574
Entamoeba histolytica isoleucyl-tRNA synthetase, putative 0.0061 0.0298 0.1603
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0222
Loa Loa (eye worm) hypothetical protein 0.0032 0.0118 0.0673
Brugia malayi leucyl-tRNA synthetase 0.0022 0.0054 0.0276
Echinococcus granulosus GPCR family 2 0.0019 0.0038 0.0023
Onchocerca volvulus 0.0019 0.0039 0.037
Trichomonas vaginalis penicillin-binding protein, putative 0.0044 0.0189 0.6349
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0033 0.0123 0.0148
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0001
Treponema pallidum valyl-tRNA synthetase 0.0022 0.0054 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0096 0.3224
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0021 0.0048 0.0033
Trichomonas vaginalis D-aminoacylase, putative 0.0044 0.0189 0.6349
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0048 0.0213 0.026
Onchocerca volvulus 0.0022 0.0054 0.051
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0048 0.0213 0.0593
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0048 0.0213 0.7159
Mycobacterium ulcerans methionyl-tRNA synthetase 0.0047 0.0211 0.0257
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0044 0.0189 0.023
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0054 0.0253 0.8486
Schistosoma mansoni hypothetical protein 0.0472 0.2829 0.2818
Schistosoma mansoni hypothetical protein 0.0024 0.0067 0.0052
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0067 0.0052
Wolbachia endosymbiont of Brugia malayi valyl-tRNA synthetase 0.0022 0.0054 0.0816
Loa Loa (eye worm) cysteinyl tRNA synthetase 1 0.0019 0.0039 0.0222
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0067 0.1586
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0061 0.0293 0.1575
Trypanosoma brucei cysteinyl-tRNA synthetase, putative 0.0019 0.0039 0.1299
Mycobacterium tuberculosis Probable conserved polyketide synthase associated protein PapA3 0.0019 0.004 0.0045
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0038 0.0189
Toxoplasma gondii target of rapamycin (TOR), putative 0.0021 0.0048 0.0133
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0108 0.0588 0.0574
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0122 0.0694
Loa Loa (eye worm) hypothetical protein 0.0019 0.0038 0.0215
Mycobacterium tuberculosis Conserved protein 0.0023 0.0061 0.0072
Echinococcus granulosus beta LACTamase domain containing family member 0.0044 0.0189 0.0175
Trypanosoma cruzi isoleucyl-tRNA synthetase, putative 0.0061 0.0298 1
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0021 0.0048 0.0995
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0029 0.0096 0.0081
Trypanosoma brucei leucyl-tRNA synthetase, putative 0.0022 0.0054 0.1793
Schistosoma mansoni microtubule-associated protein tau 0.1635 1 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0067 0.0333 0.0319
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0067 0.0052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0097
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0019 0.0039 0.0024
Chlamydia trachomatis isoleucine--tRNA ligase 0.0061 0.0298 0.156
Entamoeba histolytica valyl-tRNA synthetase, putative 0.0022 0.0054 0.0276
Mycobacterium leprae Probable lipase LipE 0.0044 0.0189 0.023
Brugia malayi isocitrate dehydrogenase 0.0019 0.0038 0.019
Mycobacterium tuberculosis Unknown protein 0.0019 0.004 0.0045
Mycobacterium tuberculosis Possible conserved polyketide synthase associated protein PapA5 0.0019 0.004 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0092 0.0485
Schistosoma mansoni glycyl-tRNA synthetase 0.017 0.0964 0.0951
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Mycobacterium leprae Probable cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.133 0.8117 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0021 0.0048 0.0995
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0021 0.0048 0.0033
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0067 0.0052
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0018 0.0028 0.0158
Brugia malayi intermediate filament protein 0.0033 0.0122 0.0645
Mycobacterium tuberculosis Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA glycosylase) 0.0093 0.0491 0.0602
Giardia lamblia Leucyl-tRNA synthetase 0.0056 0.0265 0.8818
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.133 0.8117 1
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0021 0.0048 0.0246
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0044 0.0189 0.023
Mycobacterium leprae Probable methionyl-tRNA synthase MetS 0.0047 0.0211 0.0257
Echinococcus multilocularis leucyl tRNA synthetase 0.0069 0.0345 0.0331
Schistosoma mansoni hypothetical protein 0.0019 0.0038 0.0023
Onchocerca volvulus 0.0018 0.0032 0.0301
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0033 0.0123 0.0702
Mycobacterium leprae POSSIBLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA5 0.0019 0.004 0.0045
Plasmodium falciparum cysteine--tRNA ligase 0.0019 0.0039 0.0396
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0189 0.5281
Leishmania major hypothetical protein, conserved 0.0044 0.0189 0.5215
Echinococcus multilocularis valyl tRNA synthetase 0.0022 0.0054 0.0039
Wolbachia endosymbiont of Brugia malayi methionyl-tRNA synthetase 0.0047 0.0211 0.4118
Mycobacterium ulcerans leucyl-tRNA synthetase 0.006 0.0292 0.0356
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0048 0.0246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Toxoplasma gondii ABC1 family protein 0.0044 0.0189 0.0526
Echinococcus multilocularis cysteinyl tRNA synthetase 0.0019 0.0039 0.0024
Echinococcus multilocularis lamin dm0 0.0033 0.0122 0.0107
Leishmania major leucyl-tRNA synthetase, putative 0.0069 0.0345 0.9876
Toxoplasma gondii tRNA ligases class I (M) protein 0.0047 0.0211 0.0586
Mycobacterium tuberculosis Probable esterase LipL 0.0044 0.0189 0.023
Echinococcus multilocularis glycyl tRNA synthetase 0.017 0.0964 0.0951
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0108 0.0588 0.0574
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0019 0.0039 0.1306
Echinococcus granulosus intermediate filament protein 0.0033 0.0122 0.0107
Trypanosoma brucei tyrosyl/methionyl-tRNA synthetase, putative 0.0015 0.0015 0.0487
Onchocerca volvulus 0.0044 0.0189 0.1799
Chlamydia trachomatis cysteine--tRNA ligase 0.0019 0.0039 0.0133
Trichomonas vaginalis esterase, putative 0.0044 0.0189 0.6349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Mycobacterium ulcerans polyketide synthase associated protein PapA3 0.0019 0.004 0.0045
Brugia malayi Valyl-tRNA synthetase 0.0022 0.0054 0.0276
Brugia malayi Methyltransferase-like protein 4 0.0023 0.0061 0.0316
Plasmodium vivax methionine--tRNA ligase, putative 0.0047 0.0211 0.5938
Loa Loa (eye worm) hypothetical protein 0.0044 0.0189 0.1081
Loa Loa (eye worm) isoleucyl-tRNA synthetase 0.0061 0.0298 0.1703
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0108 0.0588 0.0574
Onchocerca volvulus 0.0024 0.0067 0.0639
Entamoeba histolytica hypothetical protein 0.0015 0.0015 0.0065
Echinococcus granulosus glycyl tRNA synthetase 0.017 0.0964 0.0951
Schistosoma mansoni rab6-interacting 0.0024 0.0067 0.0052
Brugia malayi Doublecortin family protein 0.0024 0.0067 0.035
Mycobacterium ulcerans beta-lactamase 0.0044 0.0189 0.023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0048 0.1612
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0038 0.1261

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 1.3 nM Agonist activity at human KOR expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by luminescence assay ChEMBL. 25426797
Emax (functional) = 100 % Agonist activity at human KOR expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by luminescence assay ChEMBL. 25426797

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.