Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Pre-SET motif family protein | 0.0237 | 0.8733 | 0.8755 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0665 | 0.0666 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | acetyltransferase | 0.0142 | 0.5102 | 0.5115 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0009 | 0.0009 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.2578 | 0.259 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0933 | 0.0938 |
Onchocerca volvulus | 0.0065 | 0.2118 | 0.2111 | |
Onchocerca volvulus | 0.0055 | 0.1737 | 0.173 | |
Brugia malayi | CHE-14 protein | 0.0042 | 0.1253 | 0.1248 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1253 | 0.1256 |
Echinococcus multilocularis | protein dispatched 1 | 0.0048 | 0.1482 | 0.1486 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.0402 | 0.5 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0933 | 0.2945 |
Toxoplasma gondii | fructose-1,6-bisphosphate aldolase | 0.0089 | 0.3058 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0009 | 0.0009 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0317 | 0.0309 |
Echinococcus multilocularis | fructose bisphosphate aldolase class I | 0.0089 | 0.3058 | 0.3067 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.001 | 0.0009 | 0.0009 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0027 | 0.0665 | 0.2041 |
Schistosoma mansoni | glutaminase | 0.0268 | 0.9952 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1292 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0009 | 0.0009 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.1118 | 0.1113 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0042 | 0.1237 | 0.0067 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0665 | 0.055 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.001 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1118 | 0.1121 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.1103 | 0.2867 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0009 | 0.0009 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0014 | 0.0174 | 0.0187 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0089 | 0.3058 | 0.3234 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0009 | 0.0009 |
Brugia malayi | hypothetical protein | 0.0065 | 0.2118 | 0.2117 |
Echinococcus multilocularis | dna polymerase kappa | 0.004 | 0.1178 | 0.1181 |
Echinococcus multilocularis | expressed conserved protein | 0.0092 | 0.3185 | 0.3194 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1292 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0933 | 0.0928 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0402 | 0.0403 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.1103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.3415 | 0.3424 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.1178 | 0.0813 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.003 | 0.0801 | 0.0877 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.1253 | 0.1256 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0009 | 0.0009 |
Leishmania major | hypothetical protein, conserved | 0.0077 | 0.2578 | 0.2695 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0082 | 0.2799 | 0.2807 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1292 |
Schistosoma mansoni | fructose 16-bisphosphate aldolase | 0.0089 | 0.3058 | 0.3073 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0317 | 0.0319 |
Brugia malayi | hypothetical protein | 0.0269 | 0.9973 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0665 | 0.1514 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0665 | 0.0275 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0027 | 0.0665 | 0.0275 |
Mycobacterium tuberculosis | Probable phytoene synthase PhyA | 0.0077 | 0.2578 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0665 | 0.0275 |
Onchocerca volvulus | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog | 0.0077 | 0.2578 | 0.2571 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0009 | 0.0009 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.0089 | 0.3058 | 0.3067 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.1253 | 0.1256 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0009 | 0.0009 |
Plasmodium vivax | fructose 1,6-bisphosphate aldolase, putative | 0.0089 | 0.3058 | 1 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0142 | 0.5102 | 0.5111 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0009 | 0.0009 |
Echinococcus granulosus | dna polymerase kappa | 0.004 | 0.1178 | 0.1181 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0138 | 0.4948 | 0.4961 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0801 | 0.0803 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0098 | 0.3415 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0082 | 0.279 | 0.2797 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0174 | 0.0174 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0933 | 0.0938 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0009 | 0.0009 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0042 | 0.1237 | 0.0067 |
Echinococcus granulosus | Squalene phytoene synthase | 0.0077 | 0.2578 | 0.2585 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0317 | 0.0318 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0142 | 0.5102 | 0.5115 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1292 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0665 | 0.055 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0009 | 0.0009 |
Brugia malayi | bZIP transcription factor family protein | 0.0082 | 0.2799 | 0.28 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0042 | 0.1237 | 0.3954 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0402 | 0.095 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0402 | 0.0403 |
Loa Loa (eye worm) | glutaminase | 0.0268 | 0.9952 | 0.9979 |
Trichomonas vaginalis | glutaminase, putative | 0.0268 | 0.9952 | 0.9956 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.2578 | 0.2585 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.1808 | 0.1806 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0009 | 0.0009 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0933 | 0.1999 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0027 | 0.0665 | 0.1514 |
Brugia malayi | glutaminase DH11.1 | 0.0268 | 0.9952 | 0.9979 |
Trypanosoma cruzi | phytoene synthase, putative | 0.0077 | 0.2578 | 0.2695 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0009 | 0.0009 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0042 | 0.1237 | 0.124 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0082 | 0.279 | 0.2797 |
Mycobacterium ulcerans | phytoene synthase, CrtB | 0.0077 | 0.2578 | 0.2278 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.0089 | 0.3058 | 0.3067 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.1194 | 0.12 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0098 | 0.3415 | 0.3418 |
Echinococcus granulosus | fructose bisphosphate aldolase class I | 0.0089 | 0.3058 | 0.3067 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0009 | 0.0009 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.279 | 0.8071 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0402 | 0.0403 |
Trypanosoma brucei | squalene synthase, putative | 0.0246 | 0.9094 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0317 | 0.0319 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0317 | 0.0318 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0009 | 0.0009 |
Onchocerca volvulus | 0.0027 | 0.0665 | 0.0656 | |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0033 | 0.0885 | 0.0888 |
Schistosoma mansoni | fructose 16-bisphosphate aldolase | 0.0089 | 0.3058 | 0.3073 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.2712 | 0.2719 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0317 | 0.0318 |
Brugia malayi | fructose-bisphosphate aldolase 1 | 0.0089 | 0.3058 | 0.306 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.0089 | 0.3058 | 0.3067 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1126 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0269 | 0.9973 | 1 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0014 | 0.0174 | 0.0175 |
Leishmania major | squalene synthase, putative | 0.0246 | 0.9094 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0009 | 0.0009 |
Trypanosoma cruzi | squalene synthase, putative | 0.0246 | 0.9094 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0237 | 0.8733 | 0.8756 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.1178 | 0.0813 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0082 | 0.2799 | 0.2807 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | jun-related protein | 0.0067 | 0.2205 | 0.2215 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.2205 | 0.2215 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.01 | 0.3474 | 0.349 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 0.9973 | 1 |
Mycobacterium ulcerans | glutaminase | 0.0268 | 0.9952 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0027 | 0.0665 | 0.0275 |
Echinococcus granulosus | jun protein | 0.0082 | 0.2799 | 0.2807 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.279 | 0.8071 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0034 | 0.0929 | 0.1017 |
Toxoplasma gondii | fructose-bisphosphate aldolase, putative | 0.0089 | 0.3058 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0009 | 0.0009 |
Leishmania major | fructose-1,6-bisphosphate aldolase | 0.0089 | 0.3058 | 0.3234 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1292 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0269 | 0.9973 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.1178 | 0.1292 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0082 | 0.279 | 0.2803 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.0423 | 0.1037 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.1103 | 0.2638 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0253 | 0.0274 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.1253 | 0.1256 |
Schistosoma mansoni | DNA polymerase eta | 0.0014 | 0.0174 | 0.0175 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.1737 | 0.1746 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.1253 | 0.1259 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0027 | 0.0665 | 0.0275 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0665 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.0665 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0317 | 0.0318 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.0423 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0665 | 0.0666 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.1194 | 0.12 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0253 | 0.0274 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0317 | 0.0318 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0042 | 0.1237 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1808 | 0.1813 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0098 | 0.3415 | 0.3424 |
Plasmodium falciparum | fructose-bisphosphate aldolase | 0.0089 | 0.3058 | 1 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1551 | 0.1558 |
Schistosoma mansoni | transient receptor potential channel | 0.001 | 0.0009 | 0.0009 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.036 | 0.0774 |
Brugia malayi | MH2 domain containing protein | 0.0136 | 0.4851 | 0.4859 |
Schistosoma mansoni | survival motor neuron protein | 0.0055 | 0.1737 | 0.1746 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.036 | 0.0774 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0014 | 0.0174 | 0.0174 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0089 | 0.3058 | 0.3234 |
Toxoplasma gondii | fructose-1,6-bisphosphate aldolase | 0.0089 | 0.3058 | 1 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0089 | 0.3058 | 0.3234 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.1808 | 0.1813 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0402 | 0.0403 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1292 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1292 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.1194 | 0.12 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.001 | 0.0009 | 0.0009 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0317 | 0.0318 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0009 | 0.0009 |
Trypanosoma cruzi | squalene synthase, putative | 0.0246 | 0.9094 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.0423 | 0.0279 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0933 | 0.0938 |
Echinococcus granulosus | expressed conserved protein | 0.0092 | 0.3185 | 0.3194 |
Echinococcus multilocularis | dna polymerase eta | 0.0014 | 0.0174 | 0.0174 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.0089 | 0.3058 | 0.3067 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0009 | 0.0009 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0665 | 0.0658 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0141 | 0.504 | 0.5054 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0034 | 0.0933 | 0.0936 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0253 | 0.0274 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0317 | 0.0318 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0009 | 0.0009 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0665 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.1253 | 0.0084 |
Echinococcus multilocularis | jun protein | 0.0082 | 0.2799 | 0.2807 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1618 | 0.1623 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0014 | 0.0174 | 0.0166 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0665 | 0.055 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1292 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0136 | 0.4851 | 0.4864 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0009 | 0.0009 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0014 | 0.0174 | 0.0174 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.0089 | 0.3058 | 0.3067 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.1253 | 0.1256 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0042 | 0.1237 | 0.3954 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.279 | 0.8071 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0933 | 0.0936 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.1118 | 0.1124 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0009 | 0.0009 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0141 | 0.504 | 0.5054 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.036 | 0.0774 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0009 | 0.0009 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1292 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1126 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0317 | 0.0319 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0317 | 0.0309 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.036 | 0.0774 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0665 | 0.0658 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0317 | 0.0319 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0665 | 0.1514 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0402 | 0.0403 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.1253 | 0.1256 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.1178 | 0.1292 |
Echinococcus granulosus | transient receptor potential cation channel | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0009 | 0.0009 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0055 | 0.1737 | 0.1735 |
Echinococcus granulosus | dna polymerase eta | 0.0014 | 0.0174 | 0.0174 |
Loa Loa (eye worm) | glutaminase 2 | 0.0268 | 0.9952 | 0.9979 |
Trichomonas vaginalis | set domain proteins, putative | 0.0269 | 0.9991 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0027 | 0.0665 | 0.0275 |
Brugia malayi | polk-prov protein | 0.003 | 0.0801 | 0.0795 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.279 | 0.8071 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0009 | 0.0009 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0317 | 0.0318 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.001 | 0.0009 | 0.0009 |
Brugia malayi | hypothetical protein | 0.0082 | 0.279 | 0.2791 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0009 | 0.0009 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0027 | 0.0665 | 0.2041 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.279 | 0.2803 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0142 | 0.5102 | 0.5126 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0665 | 0.0666 |
Echinococcus multilocularis | Squalene phytoene synthase | 0.0077 | 0.2578 | 0.2585 |
Brugia malayi | fructose-bisphosphate aldolase 2 | 0.0089 | 0.3058 | 0.306 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0136 | 0.4851 | 0.4864 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0665 | 0.0275 |
Trypanosoma brucei | unspecified product | 0.0034 | 0.0929 | 0.1017 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0014 | 0.0174 | 0.0175 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0933 | 0.0936 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.1808 | 0.1806 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.0933 | 0.0938 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1126 |
Trypanosoma brucei | fructose-bisphosphate aldolase, glycosomal, putative | 0.0089 | 0.3058 | 0.336 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0665 | 0.0658 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0423 | 0.0461 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0014 | 0.0174 | 0.0166 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0009 | 0.0009 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0089 | 0.3058 | 0.3234 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.003 | 0.0801 | 0.0877 |
Loa Loa (eye worm) | fructose-bisphosphate aldolase 1 | 0.0089 | 0.3058 | 0.3067 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0009 | 0.0009 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.0089 | 0.3058 | 0.3067 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0009 | 0.0009 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.1194 | 0.12 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.1178 | 0.1126 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0009 | 0.0009 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0034 | 0.0933 | 0.0936 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0014 | 0.0174 | 0.0174 |
Loa Loa (eye worm) | fructose-bisphosphate aldolase 2 | 0.0089 | 0.3058 | 0.3067 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0098 | 0.3415 | 0.3424 |
Onchocerca volvulus | 0.0034 | 0.0933 | 0.0925 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.