Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.6693 | 0.6693 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.7465 | 0.7465 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.4503 | 0.4503 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.1064 | 0.1064 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.6693 | 0.6693 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.1064 | 0.1064 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.4503 | 0.4503 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.1064 | 0.1064 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.6693 | 0.6693 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.1064 | 0.1064 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.1064 | 0.1064 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.7465 | 0.7465 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.6693 | 0.6693 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.7465 | 0.7465 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.1064 | 0.1064 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.4503 | 0.4503 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.6693 | 0.6693 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.1064 | 0.1064 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.6693 | 0.6693 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.6693 | 0.6693 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.1064 | 0.1064 |
Brugia malayi | TAR-binding protein | 0.0063 | 1 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.1064 | 0.1064 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.1064 | 0.1064 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.7465 | 0.7465 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.6693 | 0.6693 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.1064 | 0.1064 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.1064 | 0.1064 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.6693 | 0.6693 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.