Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0199 | 0 | 0.5 |
Onchocerca volvulus | 0.0199 | 0 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.1178 | 1 | 1 |
Onchocerca volvulus | 0.0199 | 0 | 0.5 | |
Onchocerca volvulus | 0.0199 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.1178 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1178 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.1178 | 1 | 1 |
Onchocerca volvulus | 0.0199 | 0 | 0.5 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0199 | 0 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0199 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0199 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0199 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.1178 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1178 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0199 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1178 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1178 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1178 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1178 | 1 | 1 |
Onchocerca volvulus | 0.0199 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.1178 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1178 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.