Detailed information for compound 974523

Basic information

Technical information
  • TDR Targets ID: 974523
  • Name: 3,5-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-6 ,7,8-trimethoxychromen-4-one
  • MW: 390.341 | Formula: C19H18O9
  • H donors: 3 H acceptors: 4 LogP: 2.76 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1O)c1oc2c(OC)c(OC)c(c(c2c(=O)c1O)O)OC
  • InChi: 1S/C19H18O9/c1-24-10-6-5-8(7-9(10)20)15-14(23)12(21)11-13(22)17(25-2)19(27-4)18(26-3)16(11)28-15/h5-7,20,22-23H,1-4H3
  • InChiKey: MSJSUAMCRPCVFM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3,5-dihydroxy-2-(3-hydroxy-4-methoxy-phenyl)-6,7,8-trimethoxy-chromen-4-one
  • 3,5-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7,8-trimethoxy-4-chromenone
  • 3,5-dihydroxy-2-(3-hydroxy-4-methoxy-phenyl)-6,7,8-trimethoxy-chromone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major proteasome beta 3 subunit, putative 0.0138 0.1676 0.1676
Schistosoma mansoni RAR-like nuclear receptor 0.0025 0.0166 0.0166
Brugia malayi proteasome subunit beta type 3 0.0138 0.1676 0.1676
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0016 0.0057 0.0057
Loa Loa (eye worm) proteasome subunit beta type 3 0.0138 0.1676 0.1676
Echinococcus granulosus geminin 0.0221 0.2783 0.2783
Plasmodium vivax proteasome subunit beta type-1, putative 0.0191 0.2391 0.2391
Loa Loa (eye worm) steroid hormone receptor 0.0025 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0125 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0177 0.0177
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0017 0.0069 0.0069
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0147 0.1807 0.1807
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0142 0.1732 0.1732
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0013 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0021 0.0112 0.0112
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0156 0.1923 0.1923
Echinococcus granulosus subfamily T1A non peptidase ue 0.0147 0.1807 0.1807
Schistosoma mansoni hypothetical protein 0.0022 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0011
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0122 0.1472 0.1472
Echinococcus granulosus carbonic anhydrase 0.0036 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0125 0.0125
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.005 0.0506 0.0506
Echinococcus granulosus proteasome subunit alpha type 6 0.0148 0.1814 0.1814
Loa Loa (eye worm) hypothetical protein 0.0025 0.0166 0.0166
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0025 0.0166 0.0166
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0156 0.1923 0.1923
Schistosoma mansoni caspase-7 (C14 family) 0.0294 0.377 0.377
Entamoeba histolytica hypothetical protein 0.0022 0.0132 0.0132
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.0022 0.0136 0.0136
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0025 0.0166 0.0166
Plasmodium vivax metacaspase 1, putative 0.0201 0.252 0.252
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.0021 0.0115 0.0115
Schistosoma mansoni cercarial elastase (S01 family) 0.0022 0.0125 0.0125
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.0019 0.0088 0.0088
Leishmania major proteasome beta 5 subunit, putative 0.0761 1 1
Giardia lamblia 20S proteasome alpha subunit 5 0.0147 0.1807 0.1807
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0201 0.252 0.252
Giardia lamblia 20S proteasome alpha subunit 6 0.0141 0.1716 0.1716
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0191 0.2391 0.2391
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0017 0.0067 0.0067
Schistosoma mansoni carbonic anhydrase-related 0.0036 0.032 0.032
Brugia malayi PCI domain containing protein 0.0017 0.0067 0.0067
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0761 1 1
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.0017 0.0069 0.0069
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0141 0.172 0.172
Schistosoma mansoni thyroid hormone receptor 0.0025 0.0166 0.0166
Giardia lamblia Proteasome subunit beta type 2 0.0156 0.1923 0.1923
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0191 0.2391 0.2391
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0017 0.0069 0.0069
Echinococcus granulosus proteasome subunit beta type 6 0.0141 0.1723 0.1723
Entamoeba histolytica proteasome regulatory subunit, putative 0.0019 0.0089 0.0089
Loa Loa (eye worm) proteasome regulatory particle 0.0021 0.0115 0.0115
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0321 0.4126 0.4126
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0134 0.1633 0.1633
Brugia malayi 26S proteasome regulatory complex subunit p97 0.0025 0.0168 0.0168
Trypanosoma brucei metacaspase 0.0201 0.252 0.252
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0122 0.1472 0.1472
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0201 0.252 0.252
Echinococcus granulosus carbonic anhydrase 0.0036 0.032 0.032
Trichomonas vaginalis 26S proteasome subunit, putative 0.0017 0.0067 0.0067
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.0025 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0022 0.0125 0.0125
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0122 0.1472 0.1472
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0036 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0166 0.0166
Entamoeba histolytica hypothetical protein 0.0023 0.0149 0.0149
Trypanosoma brucei metacaspase MCA2 0.0201 0.252 0.252
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0169 0.2097 0.2097
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0148 0.1814 0.1814
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0148 0.1814 0.1814
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0169 0.2097 0.2097
Plasmodium vivax proteasome subunit beta type-5, putative 0.0761 1 1
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0137 0.1663 0.1663
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0025 0.0166 0.0166
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0144 0.1758 0.1758
Echinococcus multilocularis FTZ F1 alpha 0.0025 0.0166 0.0166
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0025 0.0166 0.0166
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0122 0.1472 0.1319
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0141 0.172 0.172
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0148 0.1814 0.1814
Loa Loa (eye worm) hypothetical protein 0.0022 0.0125 0.0125
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0177 0.0177
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0137 0.1663 0.1663
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0148 0.1814 0.1814
Echinococcus multilocularis ecdysone induced protein 78C 0.0025 0.0166 0.0166
Echinococcus granulosus caspase 2 0.0294 0.377 0.377
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0138 0.1676 0.1676
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0019 0.0088 0.0088
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.0019 0.0088 0.0088
Brugia malayi proteasome subunit beta type 1 0.0191 0.2391 0.2391
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0166 0.0166
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0137 0.1663 0.1663
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0138 0.1676 0.1676
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0021 0.0112 0.0112
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.0019 0.0089 0.0089
Loa Loa (eye worm) proteasome subunit beta type 2 0.0156 0.1923 0.1923
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0142 0.1732 0.1732
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0025 0.0168 0.0168
Echinococcus multilocularis proteasome subunit beta type 7 0.067 0.8794 0.8794
Trypanosoma cruzi metacaspase 5, putative 0.0201 0.252 0.252
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0017 0.0061 0.0061
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.0019 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0011
Echinococcus multilocularis acylamino acid releasing enzyme 0.0025 0.0177 0.0177
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0141 0.1716 0.1716
Trypanosoma cruzi metacaspase 5, putative 0.0201 0.252 0.252
Brugia malayi prolyl oligopeptidase family protein 0.0025 0.0177 0.0177
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.0019 0.0088 0.0088
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0022 0.0125 0.0125
Onchocerca volvulus 0.0022 0.0125 0.0033
Entamoeba histolytica hypothetical protein 0.0023 0.0149 0.0149
Brugia malayi nuclear receptor NHR-88 0.0025 0.0166 0.0166
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0036 0.032 0.032
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.0025 0.0168 0.0168
Toxoplasma gondii hypothetical protein 0.0025 0.0177 0.0177
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0137 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0022 0.0125 0.0125
Brugia malayi proteasome subunit beta type 2 0.0156 0.1923 0.1923
Echinococcus multilocularis geminin 0.0221 0.2783 0.2783
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0025 0.0166 0.0136
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0138 0.1676 0.1676
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0025 0.0166 0.0166
Leishmania major proteasome beta-1 subunit, putative 0.0141 0.1723 0.1723
Loa Loa (eye worm) hypothetical protein 0.0025 0.0166 0.0166
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.0017 0.0069 0.0069
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0108 0.1279 0.1279
Entamoeba histolytica proteasome regulatory subunit, putative 0.0016 0.0057 0.0057
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0022 0.0125 0.0125
Plasmodium falciparum proteasome subunit beta type-4 0.0137 0.1663 0.1663
Schistosoma mansoni steroid hormone receptor ad4bp 0.0025 0.0166 0.0166
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0025 0.0166 0.0166
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0195 0.2444 0.2444
Leishmania major proteasome beta 2 subunit, putative 0.0195 0.2444 0.2444
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0195 0.2444 0.2444
Loa Loa (eye worm) hypothetical protein 0.0025 0.0166 0.0166
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0013 0.0011 0.0011
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0169 0.2097 0.2097
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0147 0.1807 0.1807
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.0017 0.0069 0.0069
Giardia lamblia 20S proteasome alpha subunit 7 0.0142 0.1732 0.1732
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0022 0.0125 0.0125
Leishmania major metacaspase, putative 0.0201 0.252 0.252
Brugia malayi Proteasome subunit alpha type 1 0.0131 0.1592 0.1592
Plasmodium vivax proteasome subunit beta type-4, putative 0.0137 0.1663 0.1663
Schistosoma mansoni cercarial elastase (S01 family) 0.0022 0.0125 0.0125
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0013 0.0011 0.0011
Schistosoma mansoni coup transcription factor 0.0025 0.0166 0.0166
Trichomonas vaginalis 26S proteasome regulatory subunit rpn1, putative 0.0013 0.0009 0.0009
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0019 0.0088 0.0088
Leishmania major proteasome beta 2 subunit, putative 0.0156 0.1923 0.1923
Onchocerca volvulus Prolyl endopeptidase homolog 0.0025 0.0177 0.0162
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0156 0.1923 0.1923
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0025 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0025 0.0177 0.0177
Toxoplasma gondii heat shock protein hslv, putative 0.0122 0.1472 0.1472
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0141 0.172 0.172
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0141 0.1723 0.1723
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0195 0.2444 0.2444
Brugia malayi Uncoordinated protein 44 0.0021 0.0112 0.0112
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0132 0.1597 0.1597
Schistosoma mansoni hypothetical protein 0.0017 0.0067 0.0067
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0108 0.1279 0.1279
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.0022 0.0132 0.0132
Leishmania major proteasome alpha 7 subunit, putative 0.0169 0.2097 0.2097
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0025 0.0166 0.0166
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0156 0.1923 0.1923
Schistosoma mansoni cercarial elastase (S01 family) 0.0022 0.0125 0.0125
Loa Loa (eye worm) carbonic anhydrase 3 0.0097 0.1138 0.1138
Brugia malayi proteasome subunit alpha type 4 0.0132 0.1595 0.1595
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0025 0.0177 0.0052
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.0021 0.0115 0.0115
Brugia malayi hypothetical protein 0.0082 0.0939 0.0939
Entamoeba histolytica hypothetical protein 0.0023 0.0149 0.0149
Onchocerca volvulus Protein ultraspiracle homolog 0.0025 0.0166 0.0136
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.0025 0.0168 0.0168
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0141 0.1716 0.1716
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0122 0.1472 0.1472
Trypanosoma brucei metacaspase MCA3 0.0201 0.252 0.252
Schistosoma mansoni gamma-secretase subunit aph-1 0.0119 0.1421 0.1421
Echinococcus granulosus caspase 3 0.033 0.4249 0.4249
Trichomonas vaginalis conserved hypothetical protein 0.0201 0.252 0.252
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0141 0.1723 0.1723
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0025 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0025 0.0177 0.0177
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0148 0.1814 0.1814
Schistosoma mansoni transcription factor LCR-F1 0.0023 0.0149 0.0149
Leishmania major proteasome alpha 7 subunit, putative 0.0142 0.1732 0.1732
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0141 0.172 0.172
Giardia lamblia 20S proteasome alpha subunit 3 0.0141 0.172 0.172
Loa Loa (eye worm) hypothetical protein 0.0036 0.032 0.032
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0191 0.2391 0.2391
Brugia malayi proteasome subunit alpha type 6 0.0148 0.1814 0.1814
Echinococcus multilocularis carbonic anhydrase 0.0036 0.032 0.032
Toxoplasma gondii proteasome beta subunit 0.0138 0.1676 0.1676
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0016 0.0057 0.0057
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0201 0.2526 0.2526
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0025 0.0166 0.0166
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0761 1 1
Echinococcus granulosus enteropeptidase 0.0022 0.0125 0.0125
Trypanosoma brucei metacaspase 5, putative 0.0201 0.252 0.252
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0195 0.2444 0.2444
Loa Loa (eye worm) proteasome Regulatory Particle 0.0019 0.0088 0.0088
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.0022 0.0136 0.0136
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0201 0.252 0.252
Giardia lamblia Alanyl dipeptidyl peptidase 0.0025 0.0177 0.0177
Brugia malayi Trypsin family protein 0.0022 0.0125 0.0125
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0016 0.0057 0.0057
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0141 0.172 0.172
Plasmodium vivax proteasome subunit beta type-7, putative 0.0195 0.2444 0.2444
Trypanosoma brucei proteasome beta 6 subunit 0.0191 0.2391 0.2391
Brugia malayi prolyl oligopeptidase family protein 0.0108 0.1279 0.1279
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0141 0.172 0.172
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0025 0.0166 0.0166
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0156 0.1923 0.1923
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0201 0.252 0.252
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0097 0.1138 0.1138
Schistosoma mansoni hypothetical protein 0.0221 0.2783 0.2783
Trichomonas vaginalis conserved hypothetical protein 0.0201 0.252 0.252
Schistosoma mansoni carbonic anhydrase-related 0.0036 0.032 0.032
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0201 0.252 0.252
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0025 0.0166 0.0166
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0025 0.0177 0.0177
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0169 0.2097 0.2097
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0097 0.1138 0.1138
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.0017 0.0067 0.0067
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0138 0.1676 0.1676
Brugia malayi Proteasome/cyclosome repeat family protein 0.0018 0.0082 0.0082
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0138 0.1676 0.1676
Loa Loa (eye worm) prolyl oligopeptidase 0.0025 0.0177 0.0177
Echinococcus multilocularis caspase 0.0531 0.6932 0.6932
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0025 0.0166 0.0166
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0021 0.0115 0.0115
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0142 0.1732 0.1732
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0025 0.0166 0.0166
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0137 0.1663 0.1663
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0017 0.0069 0.0069
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0195 0.2444 0.2444
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.0019 0.0088 0.0088
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0023 0.0149 0.0149
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0144 0.1758 0.1758
Leishmania major proteasome alpha 1 subunit, putative 0.0141 0.1716 0.1716
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0137 0.1663 0.1663
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0025 0.0166 0.0166
Brugia malayi Trypsin-like protease protein 5 0.0022 0.0125 0.0125
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0025 0.0168 0.0168
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0022 0.0125 0.0125
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0142 0.1732 0.1732
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0025 0.0166 0.0166
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.0017 0.0067 0.0067
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.0017 0.0067 0.0067
Mycobacterium ulcerans proteasome PrcA 0.0122 0.1472 0.1364
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0141 0.1716 0.1716
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0025 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0376 0.4859 0.4859
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0097 0.1138 0.1138
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0169 0.2097 0.2097
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.0025 0.0168 0.0168
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0169 0.2097 0.2097
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0022 0.0136 0.0136
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0141 0.1723 0.1723
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.0022 0.0136 0.0136
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.0019 0.0088 0.0088
Trypanosoma cruzi metacaspase, putative 0.0201 0.252 0.252
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0137 0.1663 0.1663
Plasmodium vivax proteasome subunit beta type-2, putative 0.0156 0.1923 0.1923
Mycobacterium ulcerans proteasome PrcB 0.0761 1 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0025 0.0166 0.0166
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.0025 0.0168 0.0168
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0761 1 1
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0141 0.1723 0.1723
Schistosoma mansoni carbonic anhydrase-related 0.0036 0.032 0.032
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0137 0.1663 0.1663
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0321 0.4126 0.4126
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.0022 0.0136 0.0136
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0148 0.1814 0.1814
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.0022 0.0132 0.0132
Echinococcus granulosus proteasome subunit alpha type 2 0.0144 0.1758 0.1758
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.0017 0.0069 0.0069
Brugia malayi 20S proteasome alpha5 subunit 0.0147 0.1807 0.1807
Leishmania major proteasome alpha 3 subunit, putative 0.0141 0.172 0.172
Echinococcus multilocularis adhesion regulating molecule 1 0.0054 0.056 0.056
Plasmodium vivax hypothetical protein, conserved 0.0201 0.252 0.252
Echinococcus multilocularis proteasome subunit beta type 6 0.0141 0.1723 0.1723
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0147 0.1807 0.1807
Loa Loa (eye worm) hypothetical protein 0.0054 0.056 0.056
Echinococcus granulosus caspase 0.0531 0.6932 0.6932
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.0017 0.0069 0.0069
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0016 0.0057 0.0057
Toxoplasma gondii 26s proteasome subunit p55, putative 0.0019 0.0089 0.0089
Echinococcus granulosus adhesion regulating molecule 1 0.0054 0.056 0.056
Loa Loa (eye worm) trypsin family protein 0.0022 0.0125 0.0125
Onchocerca volvulus Bile acid receptor homolog 0.0025 0.0166 0.0136
Brugia malayi Adhesion regulating molecule conserved region family protein 0.0054 0.056 0.056
Toxoplasma gondii proteasome subunit 0.0141 0.1723 0.1723
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0036 0.032 0.032
Entamoeba histolytica hypothetical protein, conserved 0.0025 0.0177 0.0177
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.0025 0.0168 0.0168
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0028 0.0213 0.0213
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0112 0.0112
Echinococcus multilocularis carbonic anhydrase II 0.0097 0.1138 0.1138
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.067 0.8794 0.8794
Echinococcus granulosus gamma secretase subunit aph 1 0.0119 0.1421 0.1421
Trypanosoma cruzi 20S proteasome subunit 0.0156 0.1923 0.1923
Loa Loa (eye worm) hypothetical protein 0.0022 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.0023 0.0149 0.0149
Schistosoma mansoni ankyrin 23/unc44 0.0021 0.0112 0.0112
Toxoplasma gondii proteasome subunit alpha type, putative 0.0141 0.172 0.172
Echinococcus multilocularis thyroid hormone receptor alpha 0.0025 0.0166 0.0166
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0195 0.2444 0.2444
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0025 0.0177 0.0177
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0123 0.148 0.148
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0122 0.1472 0.1472
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0018 0.0082 0.0082
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0191 0.2391 0.2391
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0169 0.2097 0.2097
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0191 0.2391 0.2391
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0025 0.0177 0.0177
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0156 0.1923 0.1923
Loa Loa (eye worm) proteasome subunit beta type 1 0.0191 0.2391 0.2391
Trypanosoma cruzi oligopeptidase b 0.0025 0.0177 0.0177
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0021 0.0112 0.0112
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0144 0.1758 0.1758
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0147 0.1807 0.1807
Brugia malayi photoreceptor-specific nuclear receptor 0.0025 0.0166 0.0166
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0169 0.2097 0.2097
Loa Loa (eye worm) hypothetical protein 0.0025 0.0166 0.0166
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0021 0.0112 0.0112
Plasmodium vivax proteasome subunit beta type-6, putative 0.0141 0.1723 0.1723
Leishmania major hypothetical protein, conserved 0.0028 0.0213 0.0213
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0134 0.1633 0.1633
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0144 0.1758 0.1758
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0017 0.0069 0.0069
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0141 0.1716 0.1716
Echinococcus granulosus transmembrane protease serine 3 0.0022 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.004
Schistosoma mansoni proteasome regulatory subunit-related 0.0019 0.0089 0.0089
Brugia malayi prolyl oligopeptidase family protein 0.0025 0.0177 0.0177
Brugia malayi prolyl oligopeptidase family protein 0.0321 0.4126 0.4126
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0025 0.0166 0.0166
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0016 0.0057 0.0057
Loa Loa (eye worm) PCI domain-containing protein 0.0019 0.0089 0.0089
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0097 0.1138 0.1138
Loa Loa (eye worm) hypothetical protein 0.0016 0.0057 0.0057
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.005 0.0506 0.0506
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.0019 0.0088 0.0088
Entamoeba histolytica prolyl oligopeptidase family protein 0.0025 0.0177 0.0177
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0147 0.1807 0.1807
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0141 0.172 0.172
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0025 0.0168 0.0168
Brugia malayi Trypsin family protein 0.0022 0.0125 0.0125
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0137 0.1663 0.1663
Trypanosoma brucei prolyl endopeptidase 0.0025 0.0177 0.0177
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0166 0.0166
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0147 0.1807 0.1807
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.0019 0.0089 0.0089
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.0021 0.0115 0.0115
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0191 0.2391 0.2391
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0147 0.1807 0.1807
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0122 0.1472 0.1472
Giardia lamblia 20S proteasome alpha subunit 2 0.0144 0.1758 0.1758
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0013 0.0011 0.0011
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0144 0.1758 0.1758
Loa Loa (eye worm) hypothetical protein 0.0294 0.377 0.377
Entamoeba histolytica prolyl oligopeptidase family protein 0.0025 0.0177 0.0177
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0141 0.1723 0.1723
Loa Loa (eye worm) hypothetical protein 0.0036 0.032 0.032
Echinococcus multilocularis Ankyrin 0.0021 0.0113 0.0113
Schistosoma mansoni thyroid hormone receptor 0.0025 0.0166 0.0166
Echinococcus multilocularis apoptotic protease activating factor 1 0.0094 0.1086 0.1086
Plasmodium vivax proteasome subunit beta type-3, putative 0.0138 0.1676 0.1676
Brugia malayi prolyl oligopeptidase family protein 0.0025 0.0177 0.0177
Toxoplasma gondii proteasome subunit alpha type, putative 0.0047 0.0461 0.0461
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.0021 0.0115 0.0115
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0022 0.0132 0.0132
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0201 0.252 0.252
Brugia malayi Trypsin family protein 0.0022 0.0125 0.0125
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0025 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0025 0.0166 0.0166
Brugia malayi hypothetical protein 0.0022 0.0125 0.0125
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0141 0.1716 0.1716
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0022 0.0125 0.0125
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0148 0.1814 0.1814
Trypanosoma brucei carbonic anhydrase-like protein 0.0097 0.1138 0.1138
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0177 0.0177
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0137 0.1663 0.1663
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0201 0.252 0.252
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0141 0.1723 0.1723
Echinococcus granulosus acylamino acid releasing enzyme 0.0025 0.0177 0.0177
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0144 0.1758 0.1758
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0025 0.0166 0.0166
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0166 0.0166
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0025 0.0166 0.0166
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0138 0.1676 0.1676
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.0022 0.0132 0.0132
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0761 1 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0057 0.0057
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.0022 0.0136 0.0136
Giardia lamblia Proteasome subunit beta type 3 0.0138 0.1676 0.1676
Echinococcus multilocularis prolyl endopeptidase 0.0025 0.0177 0.0177
Trypanosoma cruzi prolyl endopeptidase 0.0025 0.0177 0.0177
Entamoeba histolytica hypothetical protein 0.0023 0.0149 0.0149
Echinococcus granulosus death domain containing protein 0.0021 0.0112 0.0112
Echinococcus granulosus FTZ F1 alpha 0.0025 0.0166 0.0166
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.0019 0.0088 0.0088
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0156 0.1923 0.1923
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0122 0.1472 0.1472
Brugia malayi hypothetical protein 0.0094 0.1086 0.1086
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0137 0.1663 0.1663
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.0017 0.0069 0.0069
Onchocerca volvulus 0.0022 0.0125 0.0033
Giardia lamblia Proteasome subunit beta type 1 0.0191 0.2391 0.2391
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.0022 0.0132 0.0132
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0017 0.0069 0.0069
Schistosoma mansoni cercarial elastase (S01 family) 0.0022 0.0125 0.0125
Echinococcus granulosus Ankyrin 0.0021 0.0113 0.0113
Onchocerca volvulus 0.0022 0.0125 0.0033
Loa Loa (eye worm) PAS-3 protein 0.0132 0.1595 0.1595
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0141 0.1723 0.1723
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0166 0.0166
Echinococcus granulosus ecdysone induced protein 78C 0.0025 0.0166 0.0166
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0141 0.1716 0.1716
Loa Loa (eye worm) hypothetical protein 0.0025 0.0177 0.0177
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0147 0.1807 0.1807
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0201 0.252 0.252
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.0019 0.0089 0.0089
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0016 0.0057 0.0057
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0141 0.1716 0.1716
Schistosoma mansoni cercarial elastase (S01 family) 0.0022 0.0125 0.0125
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0144 0.1758 0.1758
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0022 0.0125 0.0125
Brugia malayi ecdysteroid receptor 0.0025 0.0166 0.0166
Brugia malayi proteasome subunit alpha type 2 0.0144 0.1758 0.1758
Toxoplasma gondii hypothetical protein 0.0036 0.032 0.032
Leishmania major proteasome alpha 2 subunit, putative 0.0144 0.1758 0.1758
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0141 0.1723 0.1723
Schistosoma mansoni cercarial elastase (S01 family) 0.0022 0.0125 0.0125
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0156 0.1923 0.1923
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.0017 0.0069 0.0069
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0108 0.1279 0.1279
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0036 0.032 0.032
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0054 0.056 0.056
Onchocerca volvulus 0.0022 0.0125 0.0033
Trypanosoma brucei Aph-1 protein, putative 0.0046 0.0454 0.0454
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0169 0.2097 0.2097
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0169 0.2097 0.2097
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0137 0.1663 0.1663
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0022 0.0125 0.0125
Schistosoma mansoni caspase-3 (C14 family) 0.0531 0.6932 0.6932
Echinococcus multilocularis carbonic anhydrase 0.0036 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0025 0.0166 0.0166
Giardia lamblia 20S proteasome alpha subunit 1 0.0148 0.1814 0.1814
Brugia malayi Proteasome A-type and B-type family protein 0.0141 0.1723 0.1723
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0169 0.2097 0.2097
Trypanosoma cruzi metacaspase, putative 0.0201 0.252 0.252
Echinococcus granulosus carbonic anhydrase 0.0036 0.032 0.032
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.0017 0.0067 0.0067
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0036 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0125 0.0125
Trichomonas vaginalis proteasome regulatory subunits, putative 0.0019 0.0089 0.0089
Echinococcus granulosus Proteasome subunit alpha beta 0.0142 0.1732 0.1732
Schistosoma mansoni hypothetical protein 0.0094 0.1086 0.1086
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.0025 0.0168 0.0168
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0166 0.0166
Brugia malayi Proteasome subunit alpha type 7-1 0.0169 0.2097 0.2097
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0122 0.1472 0.5
Echinococcus multilocularis glycoprotein Antigen 5 0.0022 0.0125 0.0125
Echinococcus multilocularis proteasome subunit alpha type 6 0.0148 0.1814 0.1814
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.0017 0.0069 0.0069
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0147 0.1807 0.1807
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.0017 0.0069 0.0069
Plasmodium falciparum proteasome subunit beta type-5 0.0761 1 1
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0119 0.1421 0.1421
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0141 0.1716 0.1716
Loa Loa (eye worm) prolyl oligopeptidase 0.0321 0.4126 0.4126
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0108 0.1279 0.1279
Brugia malayi proteasome subunit alpha type 1 0.0141 0.1716 0.1716
Brugia malayi Cell death protein 3 precursor 0.0294 0.377 0.377
Trichomonas vaginalis conserved hypothetical protein 0.0201 0.252 0.252
Loa Loa (eye worm) hypothetical protein 0.0082 0.0939 0.0939
Trichomonas vaginalis conserved hypothetical protein 0.0201 0.252 0.252
Loa Loa (eye worm) hypothetical protein 0.0123 0.148 0.148
Trichomonas vaginalis conserved hypothetical protein 0.0201 0.252 0.252
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0025 0.0177 0.0177
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0016 0.0057 0.0057
Echinococcus granulosus Proteasome subunit alpha type 7 0.0169 0.2097 0.2097
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0025 0.0166 0.0166
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0138 0.1676 0.1676
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0025 0.0177 0.0177
Giardia lamblia 26S proteasome regulatory subunit, putative 0.0013 0.0009 0.0009
Echinococcus granulosus Dipeptidyl peptidase 9 0.0108 0.1279 0.1279
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0025 0.0177 0.0177
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0017 0.0069 0.0069
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0156 0.1923 0.1923
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.0021 0.0115 0.0115
Giardia lamblia Hypothetical protein 0.0021 0.0115 0.0115
Entamoeba histolytica proteasome regulatory subunit, putative 0.0021 0.0115 0.0115
Schistosoma mansoni hypothetical protein 0.0123 0.148 0.148
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0141 0.1716 0.1716
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0025 0.0166 0.0166
Echinococcus multilocularis enteropeptidase 0.0022 0.0125 0.0125
Onchocerca volvulus 0.0025 0.0166 0.0136
Brugia malayi Protein kinase domain containing protein 0.0021 0.0112 0.0112
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0141 0.172 0.172
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0201 0.252 0.252
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0321 0.4126 0.4126
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0025 0.0166 0.0166
Trypanosoma brucei Metacaspase-4 0.0201 0.252 0.252
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0148 0.1814 0.1814
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0142 0.1732 0.1732
Toxoplasma gondii hypothetical protein 0.0015 0.004 0.004
Giardia lamblia Alanyl dipeptidyl peptidase 0.0025 0.0177 0.0177
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0191 0.2391 0.2391
Echinococcus multilocularis proteasome subunit alpha type 2 0.0144 0.1758 0.1758
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0016 0.0057 0.0057
Echinococcus multilocularis Mastin 0.0022 0.0125 0.0125
Echinococcus multilocularis caspase 8 0.0201 0.252 0.252
Loa Loa (eye worm) PCI domain-containing protein 0.0017 0.0067 0.0067
Onchocerca volvulus Cell death protein 3 homolog 0.0294 0.377 0.9113
Brugia malayi hypothetical protein 0.0013 0.0011 0.0011
Trypanosoma brucei prolyl oligopeptidase, putative 0.0025 0.0177 0.0177
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0025 0.0168 0.0168
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0025 0.0166 0.0166
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0017 0.0069 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0025 0.0166 0.0166
Echinococcus granulosus carbonic anhydrase II 0.0097 0.1138 0.1138
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.0018 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0067 0.0736 0.0736
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0025 0.0177 0.0177
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0108 0.1279 0.1279
Schistosoma mansoni retinoic acid receptor RXR 0.0025 0.0166 0.0166
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0761 1 1
Schistosoma mansoni caspase-7 (C14 family) 0.0531 0.6932 0.6932
Brugia malayi Trypsin family protein 0.0022 0.0125 0.0125
Echinococcus granulosus nuclear factor of activated T cells 5 0.0201 0.2526 0.2526
Toxoplasma gondii proteasome subunit beta type, putative 0.0761 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0094 0.1086 0.1086
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0321 0.4126 1
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0148 0.1814 0.1814
Loa Loa (eye worm) RPN-3 protein 0.0022 0.0136 0.0136
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0137 0.1663 0.1663
Echinococcus granulosus netrin receptor unc 5 0.0021 0.0112 0.0112
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0017 0.0069 0.0069
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0022 0.0125 0.0125
Trypanosoma brucei proteasome beta 7 subunit 0.0137 0.1663 0.1663
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.0022 0.0132 0.0132
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0022 0.0125 0.0125
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0147 0.1807 0.1807
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.0017 0.0067 0.0067
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0122 0.1472 0.1472
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0166 0.0166
Echinococcus granulosus glycoprotein Antigen 5 0.0022 0.0125 0.0125
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0201 0.252 0.252
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0025 0.0166 0.0166
Schistosoma mansoni cercarial elastase (S01 family) 0.0022 0.0125 0.0125
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.0017 0.0069 0.0069
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0054 0.056 0.056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0025 0.0166 0.0166
Echinococcus granulosus apoptotic protease activating factor 1 0.0094 0.1086 0.1086
Brugia malayi hypothetical protein 0.0023 0.0149 0.0149
Schistosoma mansoni carbonic anhydrase 0.0036 0.032 0.032
Toxoplasma gondii PCI domain-containing protein 0.0017 0.0067 0.0067
Toxoplasma gondii PCI domain-containing protein 0.0022 0.0136 0.0136
Entamoeba histolytica prolyl oligopeptidase family protein 0.0025 0.0177 0.0177
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0156 0.1923 0.1923
Brugia malayi gamma-secretase subunit aph-1 0.0119 0.1421 0.1421
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0166 0.0166
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0761 1 1
Brugia malayi steroid hormone receptor 0.0025 0.0166 0.0166
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0138 0.1676 0.1676
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0021 0.0115 0.0115
Entamoeba histolytica proteasome regulatory subunit, putative 0.0017 0.0067 0.0067
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0191 0.2391 0.2391
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0147 0.1807 0.1807
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0025 0.0177 0.0177
Brugia malayi nuclear receptor RXR 0.0013 0.0011 0.0011
Giardia lamblia 20S proteasome alpha subunit 4 0.0169 0.2097 0.2097
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0022 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0025 0.0166 0.0166
Echinococcus granulosus proteasome prosome macropain 0.0761 1 1
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0144 0.1758 0.1758
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0138 0.1682 0.1682
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0142 0.1732 0.1732
Toxoplasma gondii peptidase, T1 family protein 0.0142 0.1732 0.1732
Schistosoma mansoni cercarial elastase (S01 family) 0.0022 0.0125 0.0125
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.0021 0.0115 0.0115
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0022 0.0132 0.0132
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0761 1 1
Echinococcus granulosus prolyl endopeptidase 0.0025 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0011
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0142 0.1732 0.1732
Leishmania major proteasome alpha 1 subunit, putative 0.0148 0.1814 0.1814
Onchocerca volvulus 0.0022 0.0125 0.0033
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0169 0.2097 0.2097
Trypanosoma brucei proteasome alpha 7 subunit 0.0142 0.1732 0.1732
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0013 0.0011 0.0011
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0097 0.1138 0.1138
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0017 0.0069 0.0069
Brugia malayi Death domain containing protein 0.0021 0.0112 0.0112
Toxoplasma gondii proteasome regulatory subunit 0.0017 0.0069 0.0069
Trypanosoma brucei oligopeptidase b 0.0025 0.0177 0.0177
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0025 0.0166 0.0166
Toxoplasma gondii prolyl endopeptidase 0.0025 0.0177 0.0177
Plasmodium falciparum metacaspase-like protein 0.0201 0.252 0.252
Loa Loa (eye worm) hypothetical protein 0.0036 0.032 0.032
Plasmodium falciparum carbonic anhydrase 0.0036 0.032 0.032
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0141 0.172 0.172
Echinococcus multilocularis caspase 3 0.033 0.4249 0.4249
Schistosoma mansoni hypothetical protein 0.0221 0.2783 0.2783
Schistosoma mansoni hypothetical protein 0.0022 0.0125 0.0125
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0531 0.6932 0.6932
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0025 0.0166 0.0166
Brugia malayi Proteasome A-type and B-type family protein 0.0137 0.1663 0.1663
Toxoplasma gondii SAC3/GANP family protein 0.0016 0.0057 0.0057
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.0017 0.0069 0.0069
Toxoplasma gondii proteasome subunit alpha1, putative 0.0148 0.1814 0.1814
Echinococcus granulosus caspase 8 0.0201 0.252 0.252
Schistosoma mansoni netrin receptor unc5 0.0021 0.0112 0.0112
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0017 0.0069 0.0069
Onchocerca volvulus 0.0094 0.1086 0.2428
Trypanosoma cruzi Aph-1 protein, putative 0.0046 0.0454 0.0454
Leishmania major carbonic anhydrase-like protein 0.0097 0.1138 0.1138
Loa Loa (eye worm) hypothetical protein 0.0201 0.252 0.252
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.0025 0.0168 0.0168
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0201 0.252 0.252
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0025 0.0177 0.0177
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0191 0.2391 0.2391
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.0017 0.0067 0.0067
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0147 0.1807 0.1807
Echinococcus granulosus Mastin 0.0022 0.0125 0.0125
Echinococcus granulosus proteasome subunit beta type 7 0.067 0.8794 0.8794
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0034 0.0296 0.0458
Brugia malayi Proteasome/cyclosome repeat family protein 0.0018 0.0082 0.0082
Onchocerca volvulus 0.0022 0.0125 0.0033
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0011 0.0011
Schistosoma mansoni cercarial elastase (S01 family) 0.0022 0.0125 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0025 0.0166 0.0166
Toxoplasma gondii PCI domain-containing protein 0.0021 0.0115 0.0115
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0011 0.0011
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0761 1 1
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0025 0.0177 0.0177
Echinococcus multilocularis netrin receptor unc 5 0.0021 0.0112 0.0112
Echinococcus multilocularis transmembrane protease serine 3 0.0022 0.0125 0.0125
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0022 0.0125 0.0125
Entamoeba histolytica proteasome regulatory subunit, putative 0.0022 0.0136 0.0136
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0169 0.2097 0.2097
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0017 0.0069 0.0069
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0022 0.0125 0.0125
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0201 0.252 0.252
Echinococcus multilocularis caspase 2 0.0294 0.377 0.377
Echinococcus multilocularis carbonic anhydrase 0.0036 0.032 0.032
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0021 0.0113 0.0113
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0147 0.1807 0.1807
Loa Loa (eye worm) hypothetical protein 0.0021 0.0112 0.0112
Schistosoma mansoni 26S proteasome subunit S9 0.0021 0.0115 0.0115
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0137 0.1663 0.1663
Brugia malayi Proteasome A-type and B-type family protein 0.067 0.8794 0.8794
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0761 1 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0201 0.252 0.252
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.0019 0.0088 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0201 0.252 0.252
Brugia malayi hypothetical protein 0.0013 0.0011 0.0011
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0022 0.0136 0.0136
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.0017 0.0067 0.0067
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0097 0.1138 0.1138
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0141 0.172 0.172
Plasmodium falciparum peptidase, putative 0.0025 0.0177 0.0177
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0201 0.252 0.252
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0147 0.1807 0.1807
Schistosoma mansoni cercarial elastase (S01 family) 0.0022 0.0125 0.0125
Echinococcus multilocularis gamma secretase subunit aph 1 0.0119 0.1421 0.1421
Brugia malayi Steroid receptor seven-up type 2 0.0025 0.0166 0.0166
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.0019 0.0089 0.0089
Plasmodium falciparum metacaspase 1 0.0201 0.252 0.252
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.0019 0.0089 0.0089
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0016 0.0057 0.0057
Leishmania major proteasome beta 7 subunit, putative 0.0137 0.1663 0.1663
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0025 0.0177 0.0177
Brugia malayi proteasome subunit alpha type 3 0.0142 0.1732 0.1732
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0025 0.0168 0.0168
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0108 0.1279 0.1279
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0141 0.1716 0.1716
Schistosoma mansoni hypothetical protein 0.0036 0.032 0.032
Brugia malayi PCI domain containing protein 0.0019 0.0089 0.0089
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0141 0.1723 0.1723
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.0019 0.0089 0.0089
Trypanosoma cruzi metacaspase, putative 0.0201 0.252 0.252
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0025 0.0177 0.0177
Onchocerca volvulus Notchless protein homolog 0.0142 0.1732 0.4037
Echinococcus granulosus proteasome subunit beta t family 0.0138 0.1676 0.1676
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0156 0.1923 0.1923
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0141 0.172 0.172
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0097 0.1138 0.1138
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.0019 0.0089 0.0089
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0531 0.6932 0.6932
Trypanosoma cruzi metacaspase, putative 0.0201 0.252 0.252
Entamoeba histolytica proteasome regulatory subunit, putative 0.0019 0.0088 0.0088
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0108 0.1279 0.1279
Brugia malayi small heat shock protein 0.0376 0.4859 0.4859
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0138 0.1676 0.1676
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0142 0.1732 0.1732
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0025 0.0166 0.0166
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.0019 0.0088 0.0088
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0761 1 1
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0142 0.1732 0.1732
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0016 0.0057 0.0057
Trypanosoma cruzi oligopeptidase b 0.0025 0.0177 0.0177
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0025 0.0177 0.0177
Leishmania major oligopeptidase b 0.0025 0.0177 0.0177
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0016 0.0057 0.0057
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0195 0.2444 0.2444
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0016 0.0057 0.0057
Schistosoma mansoni cercarial elastase (S01 family) 0.0022 0.0125 0.0125
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0016 0.0057 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0025 0.0166 0.0166
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0137 0.1663 0.1663
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0036 0.032 0.032
Trypanosoma cruzi Aph-1 protein, putative 0.0046 0.0454 0.0454
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.0021 0.0115 0.0115
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0141 0.1716 0.1716
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0142 0.1732 0.1732
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.0022 0.0136 0.0136
Echinococcus multilocularis proteasome (prosome, macropain) 0.0761 1 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0022 0.0125 0.0125
Brugia malayi nuclear hormone receptor 0.0025 0.0166 0.0166
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0122 0.1472 0.1319
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0195 0.2444 0.2444
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0108 0.1279 0.1279
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0025 0.0166 0.0166
Schistosoma mansoni hypothetical protein 0.005 0.0506 0.0506
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0017 0.0069 0.0069
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.0022 0.0136 0.0136
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0025 0.0177 0.0177
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0023 0.0149 0.0149
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0191 0.2391 0.2391

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 6 ug ml-1 Cytotoxicity against human KB cells ChEMBL. 7964782

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 7964782

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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