Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1253 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1253 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1253 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0387 | 0.0856 | 0.0861 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1253 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1253 | 1 | 1 |
Onchocerca volvulus | 0.056 | 0.269 | 1 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0477 | 0.1807 | 0.1807 |
Onchocerca volvulus | 0.056 | 0.269 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.056 | 0.269 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.056 | 0.269 | 1 |
Echinococcus granulosus | cathepsin b | 0.1247 | 0.9939 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0477 | 0.1807 | 0.1807 |
Leishmania major | cathepsin L-like protease | 0.056 | 0.269 | 0.1078 |
Entamoeba histolytica | cysteine proteinase, putative | 0.056 | 0.269 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.056 | 0.269 | 0.2019 |
Brugia malayi | Cathepsin L-like precursor | 0.056 | 0.269 | 0.2707 |
Echinococcus granulosus | cathepsin l1 | 0.056 | 0.269 | 0.2707 |
Loa Loa (eye worm) | fibroinase | 0.056 | 0.269 | 0.2019 |
Loa Loa (eye worm) | ctsf protein | 0.056 | 0.269 | 0.2019 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1253 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.056 | 0.269 | 1 |
Leishmania major | cathepsin L-like protease | 0.056 | 0.269 | 0.1078 |
Loa Loa (eye worm) | cathepsin B | 0.0477 | 0.1807 | 0.1047 |
Leishmania major | cathepsin L-like protease | 0.056 | 0.269 | 0.1078 |
Giardia lamblia | Cathepsin B precursor | 0.0477 | 0.1807 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.056 | 0.269 | 0.2707 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1253 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.056 | 0.269 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.056 | 0.269 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.056 | 0.269 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0387 | 0.0856 | 0.0861 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.056 | 0.269 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0387 | 0.0856 | 0.0861 |
Echinococcus multilocularis | cathepsin b | 0.1247 | 0.9939 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1247 | 0.9939 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1247 | 0.9939 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.056 | 0.269 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.056 | 0.269 | 0.2019 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1253 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0477 | 0.1807 | 0.1818 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.056 | 0.269 | 0.2707 |
Entamoeba histolytica | cysteine protease, putative | 0.056 | 0.269 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.056 | 0.269 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.056 | 0.269 | 0.2707 |
Plasmodium vivax | vivapain-2 | 0.056 | 0.269 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.056 | 0.269 | 0.1078 |
Giardia lamblia | Cathepsin B precursor | 0.0477 | 0.1807 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0477 | 0.1807 | 0.6717 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0387 | 0.0856 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.056 | 0.269 | 0.2707 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1247 | 0.9939 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0824 | 0.5476 | 0.5476 |
Onchocerca volvulus | 0.056 | 0.269 | 1 | |
Onchocerca volvulus | 0.056 | 0.269 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.056 | 0.269 | 0.2707 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Onchocerca volvulus | 0.056 | 0.269 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.056 | 0.269 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1253 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Leishmania major | cathepsin L-like protease | 0.1253 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.056 | 0.269 | 0.2707 |
Giardia lamblia | Cathepsin B precursor | 0.0477 | 0.1807 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0387 | 0.0856 | 0.0861 |
Onchocerca volvulus | Cathepsin L homolog | 0.056 | 0.269 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1253 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1247 | 0.9939 | 0.9939 |
Leishmania major | cathepsin L-like protease | 0.056 | 0.269 | 0.1078 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1253 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.056 | 0.269 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.056 | 0.269 | 0.2707 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.056 | 0.269 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.056 | 0.269 | 0.2707 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.056 | 0.269 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1253 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.056 | 0.269 | 0.2707 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1253 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1247 | 0.9939 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0387 | 0.0856 | 0.0861 |
Brugia malayi | Cathepsin L-like precursor | 0.056 | 0.269 | 0.2707 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1253 | 1 | 1 |
Onchocerca volvulus | 0.056 | 0.269 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1253 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1247 | 0.9939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.056 | 0.269 | 1 |
Echinococcus multilocularis | cysteine protease | 0.056 | 0.269 | 0.2707 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0387 | 0.0856 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.056 | 0.269 | 0.1078 |
Onchocerca volvulus | 0.056 | 0.269 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0387 | 0.0856 | 0.3182 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.056 | 0.269 | 0.2707 |
Echinococcus granulosus | cathepsin b | 0.1247 | 0.9939 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.056 | 0.269 | 0.2707 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.1079 | 0.8166 | 0.8166 |
Echinococcus multilocularis | cysteine protease | 0.056 | 0.269 | 0.2707 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.056 | 0.269 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0387 | 0.0856 | 0.0861 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.056 | 0.269 | 0.2707 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.1247 | 0.9939 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.056 | 0.269 | 0.2019 |
Loa Loa (eye worm) | cysteine protease | 0.056 | 0.269 | 0.2019 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.056 | 0.269 | 1 |
Echinococcus multilocularis | cathepsin b | 0.1247 | 0.9939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.056 | 0.269 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.056 | 0.269 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.056 | 0.269 | 0.269 |
Brugia malayi | Cathepsin L-like precursor | 0.056 | 0.269 | 0.2707 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.056 | 0.269 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1253 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.056 | 0.269 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.