Detailed information for compound 976632

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 408.497 | Formula: C22H28N6O2
  • H donors: 3 H acceptors: 4 LogP: 3.36 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCNC(=O)c1ccc(c(c1)Nc1ncnn2c1c(C)c(c2)C(=O)NCCC)C
  • InChi: 1S/C22H28N6O2/c1-5-9-23-21(29)16-8-7-14(3)18(11-16)27-20-19-15(4)17(22(30)24-10-6-2)12-28(19)26-13-25-20/h7-8,11-13H,5-6,9-10H2,1-4H3,(H,23,29)(H,24,30)(H,25,26,27)
  • InChiKey: CWRGMHQEWQUXJL-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens mitogen-activated protein kinase 14 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania infantum mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma brucei gambiense mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Brugia malayi P38 map kinase family protein 2 Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma congolense mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Schistosoma japonicum ko:K04441 p38 MAP kinase, putative Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus granulosus mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus granulosus mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Candida albicans MAP kinase involved in osmoregulation Get druggable targets OG5_128610 All targets in OG5_128610
Candida albicans MAP kinase involved in osmoregulation Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma cruzi mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania braziliensis mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma cruzi mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania donovani mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania mexicana mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma brucei mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 14 360 aa 336 aa 33.3 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Mycobacterium leprae putative cytochrome p450 0.0033 0.0131 0.0346
Loa Loa (eye worm) hypothetical protein 0.0101 0.0622 0.1635
Onchocerca volvulus 0.004 0.0187 0.0553
Echinococcus multilocularis lamin 0.0055 0.0293 0.0293
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0182 0.0181
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.034 0.1028
Trichomonas vaginalis Ferredoxin 4 0.0022 0.0057 0.0106
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0101 0.062 0.2245
Loa Loa (eye worm) melatonin receptor type 1A 0.0075 0.0435 0.1144
Loa Loa (eye worm) cytochrome P450 family protein 0.005 0.0259 0.068
Brugia malayi Bromodomain containing protein 0.0081 0.0475 0.1216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0388 0.0792
Echinococcus multilocularis ferredoxin adrenodoxin 0.0022 0.0057 0.0056
Trichomonas vaginalis aldehyde oxidase, putative 0.069 0.4826 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.2099 0.4342
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.001 0.0009
Echinococcus multilocularis serine protein kinase ATM 0.0017 0.0023 0.0022
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0435 0.0435
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.015 0.0973 0.2989
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.1735 0.3586
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0075 0.0435 0.0435
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.034 0.0693
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0017
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0017 0.0042
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0095 0.0575 0.0574
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Schistosoma mansoni hypothetical protein 0.0036 0.0155 0.0154
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0075 0.0435 0.0435
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0108
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0368 0.037
Loa Loa (eye worm) hypothetical protein 0.0203 0.1352 0.3555
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0044 0.0031
Schistosoma mansoni apoptosis regulator bax 0.0087 0.0522 0.0521
Echinococcus multilocularis lamin dm0 0.0055 0.0293 0.0293
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0101 0.062 0.0619
Loa Loa (eye worm) CYP4Cod1 0.005 0.0259 0.068
Mycobacterium ulcerans hypothetical protein 0.0101 0.062 0.1857
Echinococcus granulosus tyrosine protein kinase Src64B 0.004 0.0182 0.0181
Echinococcus multilocularis cpg binding protein 0.0032 0.0129 0.0128
Brugia malayi RE15519p 0.0075 0.0435 0.1116
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0146 0.0146
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0101 0.062 0.1925
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0022 0.0058 0.015
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0033 0.0131 0.0406
Schistosoma mansoni ap endonuclease 0.002 0.004 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0033 0.0131 0.0406
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0105 0.0648 0.0666
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0046 0.012
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0435 0.0435
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0422 0.0863
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0037 0.0065
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0155 0.0396
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0075 0.0435 0.1144
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0019 0.0037 0.0085
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0119 0.0342
Brugia malayi SRC-1 0.004 0.0182 0.0465
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0435 0.0435
Echinococcus multilocularis mitogen activated protein kinase 0.0105 0.0648 0.0648
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0031
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0435 0.1144
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0274 0.0718
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0101 0.062 0.0619
Schistosoma mansoni 60S ribosomal protein L21 0.0015 0.0006 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0033 0.0131 0.0406
Brugia malayi Cytochrome P450 family protein 0.005 0.0259 0.0663
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.004 0.0039
Echinococcus multilocularis glutamate synthase 0.0101 0.062 0.0619
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0187 0.0186
Schistosoma mansoni amine GPCR 0.0075 0.0435 0.0435
Trypanosoma brucei unspecified product 0.002 0.0044 0.0031
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0031 0.0119 0.0118
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0017 0.0017
Echinococcus granulosus tm gpcr rhodopsin 0.0948 0.667 0.6669
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0308 0.2099 0.8844
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0253 0.0513
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0101 0.062 0.1274
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0046 0.012
Trichomonas vaginalis glutamate synthase, putative 0.0101 0.062 0.1274
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0368 0.0367
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0101 0.062 0.1925
Echinococcus multilocularis G protein coupled receptor 139 0.0075 0.0435 0.0435
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0101 0.062 0.2245
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0435 0.0435
Schistosoma mansoni microtubule-associated protein tau 0.1414 1 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0033 0.0131 0.0406
Brugia malayi SET domain containing protein 0.0015 0.0005 0.0011
Schistosoma mansoni hypothetical protein 0.0347 0.2379 0.2378
Loa Loa (eye worm) hypothetical protein 0.0043 0.0207 0.0544
Brugia malayi hypothetical protein 0.0052 0.0267 0.0684
Echinococcus granulosus ferredoxin 0.0022 0.0057 0.0056
Echinococcus granulosus g protein coupled receptor 0.0075 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0203 0.1352 0.3555
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0717 0.0734
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0187 0.053
Entamoeba histolytica thioredoxin reductase, putative 0.0101 0.062 0.2544
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0101 0.062 0.0633
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0101 0.062 0.2544
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0368 0.037
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0017 0.0023 0.0022
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0101 0.062 0.0633
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0161 0.0323
Loa Loa (eye worm) hypothetical protein 0.0043 0.0207 0.0544
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.012
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0119 0.0342
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.003 0.0051
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0022 0.0058 0.015
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0119 0.011
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0044 0.0031
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0182 0.0181
Echinococcus granulosus cGMP dependent protein kinase 0.0016 0.001 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.2099 0.4342
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0101 0.062 0.1925
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.1735 0.3586
Echinococcus granulosus 7TM GPCR rhodopsin 0.0075 0.0435 0.0435
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0017 0.0043
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0279 0.1895 0.486
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.012
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0161 0.0412
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.034 0.0339
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0046 0.0046
Onchocerca volvulus 0.0075 0.0435 0.129
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0119 0.0308
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0119 0.0308
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0022 0.0057 0.0054
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0046 0.0046
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0017 0.0017
Entamoeba histolytica disulphide oxidoreductase, putative 0.0101 0.062 0.2544
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0033 0.0131 0.0291
Schistosoma mansoni intermediate filament proteins 0.0055 0.0293 0.0293
Schistosoma mansoni voltage-gated potassium channel 0.009 0.054 0.054
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0058
Brugia malayi G-protein coupled receptor 0.0075 0.0435 0.1116
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Onchocerca volvulus 0.0107 0.0661 0.1959
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0435 0.0435
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0017
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0064 0.0063
Schistosoma mansoni DNA polymerase eta 0.002 0.0044 0.0043
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0098 0.0602 0.2466
Mycobacterium ulcerans glutamate synthase subunit beta 0.0101 0.062 0.1857
Schistosoma mansoni opsin-like receptor 0.0075 0.0435 0.0435
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0075 0.0435 0.0435
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0075 0.0435 0.0435
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0101 0.062 0.1925
Mycobacterium ulcerans hypothetical protein 0.002 0.0042 0.0006
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0087 0.0522 0.0521
Mycobacterium tuberculosis Probable dehydrogenase 0.0101 0.062 0.1925
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.038 0.2617 0.8252
Leishmania major hypothetical protein, conserved 0.0052 0.0267 0.0269
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0027 0.0026
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1103 0.2277
Mycobacterium tuberculosis Possible oxygenase 0.0022 0.0057 0.0176
Brugia malayi Melatonin receptor type 1A 0.0075 0.0435 0.1116
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1358 0.9597 1
Echinococcus multilocularis dna polymerase kappa 0.002 0.0044 0.0043
Trypanosoma cruzi NADH dehydrogenase, putative 0.0101 0.062 0.0633
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1103 0.2277
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0119 0.0342
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0207 0.0207
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0033 0.0131 0.0291
Schistosoma mansoni zinc finger protein 0.0016 0.0014 0.0013
Brugia malayi G protein-coupled receptor F59B2.13 0.0075 0.0435 0.1116
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0207 0.0207
Plasmodium falciparum ferrodoxin reductase-like protein 0.0101 0.062 0.1901
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0017 0.0017
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0017 0.0023 0.001
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Plasmodium vivax SET domain protein, putative 0.0062 0.034 0.1007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.003 0.0051
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0033 0.0131 0.0291
Brugia malayi hypothetical protein 0.0043 0.0207 0.053
Mycobacterium tuberculosis Probable reductase 0.0101 0.062 0.1925
Leishmania major C-8 sterol isomerase-like protein 0.0388 0.267 0.2775
Leishmania major cytochrome p450-like protein 0.005 0.0259 0.026
Loa Loa (eye worm) AGC/PKG protein kinase 0.0016 0.001 0.0024
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0435 0.0435
Schistosoma mansoni hypothetical protein 0.0075 0.0435 0.0435
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0105 0.0648 0.0662
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0153 0.0992 0.1024
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0046 0.0046
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0075 0.0435 0.0435
Brugia malayi glutathione reductase 0.0465 0.322 0.8258
Schistosoma mansoni biogenic amine (5HT) receptor 0.045 0.3112 0.3111
Echinococcus granulosus hypothetical protein 0.0802 0.5631 0.563
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0017 0.0024
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0101 0.062 0.1589
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0017
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0092 0.0556 0.0566
Mycobacterium ulcerans endonuclease IV 0.0076 0.0443 0.1292
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0046 0.0046
Schistosoma mansoni tyrosine kinase 0.004 0.0182 0.0181
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0029 0.0107 0.0107
Onchocerca volvulus 0.0075 0.0435 0.129
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1103 0.2277
Echinococcus multilocularis tyrosine protein kinase HCK 0.0032 0.0126 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0422 0.0863
Schistosoma mansoni glutamate synthase 0.0101 0.062 0.0619
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.012
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.038 0.2617 0.8117
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0348 0.0347
Mycobacterium ulcerans epimerase 0.002 0.0042 0.0006
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0435 0.0435
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0034 0.0141 0.0133
Trypanosoma cruzi NADH dehydrogenase, putative 0.0101 0.062 0.0633
Brugia malayi Tachykinin-like peptides receptor 99D 0.0075 0.0435 0.1116
Echinococcus granulosus neuropeptide receptor 0.0075 0.0435 0.0435
Schistosoma mansoni biogenic amine (5HT) receptor 0.0203 0.1352 0.1352
Loa Loa (eye worm) hypothetical protein 0.0107 0.0662 0.1739
Echinococcus multilocularis mitogen activated protein kinase 14 0.0153 0.0992 0.0991
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0033 0.0131 0.0291
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0717 0.1475
Onchocerca volvulus 0.0099 0.0604 0.1791
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0435 0.0435
Leishmania major hypothetical protein, conserved 0.0022 0.0057 0.0049
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.038 0.2617 0.8127
Onchocerca volvulus 0.0022 0.0057 0.0167
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1358 0.9597 1
Schistosoma mansoni hypothetical protein 0.0075 0.0435 0.0435
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0033 0.0131 0.0122
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.0182 0.0181
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0022 0.0058 0.0057
Schistosoma mansoni myosin xvIII 0.0075 0.0435 0.0435
Onchocerca volvulus 0.004 0.0187 0.0553
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0161 0.0158
Trichomonas vaginalis Ferredoxin 3 0.0022 0.0057 0.0106
Trypanosoma brucei hypothetical protein, conserved 0.0101 0.062 0.0633
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0054 0.014
Echinococcus granulosus mitogen activated protein kinase 14 0.0153 0.0992 0.0991
Schistosoma mansoni hypothetical protein 0.0087 0.0522 0.0521
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.004 0.0101
Mycobacterium ulcerans ferredoxin reductase 0.0101 0.062 0.1857
Echinococcus granulosus cGMP dependent protein kinase 1 0.0016 0.001 0.0009
Brugia malayi hypothetical protein 0.0075 0.0435 0.1116
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0029 0.0107 0.0107
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.0182 0.0181
Schistosoma mansoni adenoreceptor 0.0075 0.0435 0.0435
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0101 0.062 0.0619
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0092 0.0556 0.2272
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0153 0.0992 0.1021
Schistosoma mansoni cpg binding protein 0.0032 0.0129 0.0128
Brugia malayi Pre-SET motif family protein 0.0062 0.034 0.087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0161 0.0323
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0254 0.0514
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0293 0.075
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0101 0.062 0.1925
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0422 0.0863
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0101 0.062 0.0633
Schistosoma mansoni cpg binding protein 0.0029 0.0103 0.0102
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0033 0.0131 0.0406
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0999 0.7034 0.7326
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0044 0.0079
Schistosoma mansoni hypothetical protein 0.0075 0.0435 0.0435
Brugia malayi steroid hormone receptor 0.0021 0.0046 0.0117
Leishmania major NADH dehydrogenase, putative 0.0101 0.062 0.0636
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.038 0.2617 0.8252
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0101 0.062 0.1274
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0101 0.062 0.1901
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.008 0.0468 0.123
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0068
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0022 0.0058 0.0057
Brugia malayi hypothetical protein 0.0033 0.0137 0.0349
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0046 0.0046
Schistosoma mansoni sodium-dependent amino acid transporter 0.0043 0.0207 0.0207
Onchocerca volvulus 0.0021 0.0046 0.0136
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0435 0.0435
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0046 0.0046
Giardia lamblia [2Fe-2S] ferredoxin 0.0022 0.0057 0.0065
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0368 0.037
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.038 0.2617 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1143 0.8062 0.8398
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0717 0.2626
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0022 0.0057 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0031
Schistosoma mansoni rab6-interacting 0.004 0.0187 0.0186
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0042 0.0122
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0031 0.0119 0.0304
Brugia malayi isocitrate dehydrogenase 0.0017 0.0017 0.0043
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.012
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.004 0.0094
Loa Loa (eye worm) hypothetical protein 0.0038 0.0172 0.0452
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.008 0.0079
Trichomonas vaginalis set domain proteins, putative 0.0486 0.337 0.698
Schistosoma mansoni glutamate synthase 0.0101 0.062 0.0619
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0233 0.1562 0.4851
Schistosoma mansoni biogenic amine receptor 0.0075 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0037 0.0161 0.0423
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0435 0.1144
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0161 0.0154
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0999 0.7034 0.7325
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0044 0.0031
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0033 0.0131 0.0291
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0101 0.062 0.1274
Schistosoma mansoni biogenic amine receptor 0.0075 0.0435 0.0435
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0092 0.0556 0.1425
Schistosoma mansoni neuropeptide f receptor 76f 0.0075 0.0435 0.0435
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0105 0.0648 0.0662
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0075 0.0435 0.1116
Schistosoma mansoni alpha-1 adrenergic receptor 0.0075 0.0435 0.0435
Schistosoma mansoni hypothetical protein 0.0022 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0043 0.0207 0.0544
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0101 0.062 0.0636
Brugia malayi Doublecortin family protein 0.004 0.0187 0.0478
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0101 0.062 0.1589
Brugia malayi G-protein coupled receptor 0.0075 0.0435 0.1116
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Echinococcus granulosus serotonin transporter 0.0255 0.1719 0.1718
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0435 0.0435
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0141 0.0133
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0095 0.0575 0.0574
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0022 0.0057 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0036
Onchocerca volvulus Neuropeptide F receptor homolog 0.0075 0.0435 0.129
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0161 0.0154
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0022 0.0058 0.0057
Loa Loa (eye worm) norepinephrine transporter 0.0255 0.1719 0.4519
Loa Loa (eye worm) cytochrome P450 family protein 0.0091 0.0546 0.1434
Echinococcus granulosus dna polymerase kappa 0.002 0.0044 0.0043
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0103 0.0268
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0046 0.0117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1358 0.9597 1
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1103 0.2277
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0017 0.0023 0.0022
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0101 0.062 0.2251
Echinococcus granulosus tyrosine protein kinase Src42A 0.004 0.0182 0.0181
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0022 0.0058 0.0057
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0359 0.0359
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0207 0.0207
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0047 0.0231 0.0606
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0242 0.1625 0.1624
Schistosoma mansoni growth hormone secretagogue receptor 0.0075 0.0435 0.0435
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1143 0.8062 0.8398
Brugia malayi Cytochrome P450 family protein 0.005 0.0259 0.0663
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.038 0.2617 0.2616
Brugia malayi Uncoordinated protein 44 0.0014 0.0001 0.00000012476
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0101 0.062 0.1857
Loa Loa (eye worm) hypothetical protein 0.0069 0.039 0.1024
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0027 0.0026
Giardia lamblia Thioredoxin reductase 0.0101 0.062 0.2251
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0033 0.0131 0.0406
Echinococcus granulosus survival motor neuron protein 1 0.0484 0.336 0.336
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0087 0.0522 0.0521
Plasmodium vivax thioredoxin reductase, putative 0.0465 0.322 1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.001 0.001
Onchocerca volvulus 0.0075 0.0435 0.129
Treponema pallidum NADH oxidase 0.038 0.2617 1
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0204 0.1359 0.4224
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0017 0.0017
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.005 0.0259 0.0701
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0075 0.0435 0.0435
Giardia lamblia Kinase, CMGC MAPK 0.0105 0.0648 0.2361
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0388 0.0792
Echinococcus granulosus Ankyrin 0.0014 0.0001 0.0001
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0058 0.0057
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Brugia malayi Cytochrome P450 family protein 0.0033 0.0131 0.0334
Plasmodium falciparum thioredoxin reductase 0.0465 0.322 1
Echinococcus multilocularis serotonin transporter 0.0255 0.1719 0.1718
Loa Loa (eye worm) hypothetical protein 0.0255 0.1719 0.4519
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0717 0.1883
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.034 0.0339
Trypanosoma brucei NADH dehydrogenase 0.0101 0.062 0.0633
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0132 0.0839 0.256
Echinococcus multilocularis survival motor neuron protein 1 0.0484 0.336 0.336
Toxoplasma gondii selenide, water dikinase 0.0101 0.062 0.1901
Brugia malayi Pre-SET motif family protein 0.0427 0.2949 0.7564
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0044 0.0043
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0325 0.2222 0.6987
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0546 0.3803 1
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0187 0.0186
Schistosoma mansoni amine GPCR 0.0075 0.0435 0.0435
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0033 0.0131 0.0291
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0254 0.0514
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0161 0.0471
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0101 0.062 0.1857
Onchocerca volvulus 0.0074 0.0426 0.1261
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0043 0.0207 0.0588
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0325 0.2222 0.69
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0038 0.017 0.0163
Mycobacterium ulcerans NADH dehydrogenase 0.0101 0.062 0.1857
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0101 0.062 0.0633
Loa Loa (eye worm) hypothetical protein 0.0029 0.0107 0.028
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0119 0.0319
Schistosoma mansoni adrenodoxin 0.0022 0.0057 0.0056
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0101 0.062 0.1901
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0017 0.0017
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0006 0.0006
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0092 0.0556 0.0556
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Leishmania major dihydrolipoamide dehydrogenase, putative 0.038 0.2617 0.2719
Loa Loa (eye worm) hypothetical protein 0.0043 0.0205 0.0538
Echinococcus granulosus dro:myosuppressin receptor 0.0075 0.0435 0.0435
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.004 0.0182 0.0181
Schistosoma mansoni lipoxygenase 0.0242 0.1625 0.1624
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0075 0.0144
Leishmania major trypanothione reductase 0.0465 0.322 0.3348
Toxoplasma gondii FATC domain-containing protein 0.0017 0.0023 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0033 0.0131 0.0406
Loa Loa (eye worm) hypothetical protein 0.004 0.0187 0.049
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0031
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0057 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0556 0.1142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0046 0.012
Loa Loa (eye worm) doublecortin family protein 0.004 0.0187 0.049
Giardia lamblia GTOR 0.0092 0.0556 0.2003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.046 0.0943
Loa Loa (eye worm) hypothetical protein 0.0255 0.1719 0.4519
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0075 0.0432 0.0885
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0242 0.1625 0.1624
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0017 0.0004
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0057 0.0045
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0465 0.322 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.012
Toxoplasma gondii hypothetical protein 0.0043 0.0207 0.0616
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0075 0.0435 0.129
Brugia malayi Thioredoxin reductase 0.0465 0.322 0.8258
Brugia malayi G protein-coupled receptor 0.0075 0.0435 0.1116
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0075 0.0435 0.0435
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0422 0.0421
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0101 0.062 0.1925
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0046 0.0046
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0435 0.0435
Toxoplasma gondii endonuclease IV APN 0.0076 0.0443 0.1351
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.038 0.2617 0.8127
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0435 0.0435
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0033 0.0131 0.0406
Loa Loa (eye worm) hypothetical protein 0.0043 0.0207 0.0544
Loa Loa (eye worm) hypothetical protein 0.0255 0.1719 0.4519
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.003 0.0051
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0435 0.0435
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0038 0.017 0.0167
Echinococcus multilocularis tyrosine protein kinase Src64B 0.004 0.0182 0.0181
Leishmania major hypothetical protein, conserved 0.0101 0.062 0.0636
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0427 0.2949 0.7756
Leishmania major cytochrome p450-like protein 0.0033 0.0131 0.0126
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0083 0.0491 0.049
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0043 0.0207 0.053
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.0443 0.156
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0161 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0031
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0101 0.062 0.1274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0119 0.0235
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0044 0.0012
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0075 0.0435 0.0435
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0038 0.017 0.0163
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0046 0.0046
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0001 0.000000048638
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0074 0.0426 0.0425
Plasmodium vivax ferredoxin, putative 0.0022 0.0057 0.0123
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0057 0.0045
Schistosoma mansoni lamin 0.0055 0.0293 0.0293
Brugia malayi hypothetical protein 0.0075 0.0435 0.1116
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0038 0.017 0.0434
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0046 0.0136
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0001 0.000000048638
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.1735 0.3586
Echinococcus multilocularis 0.0033 0.0131 0.013
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0046 0.0046
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0274 0.07
Echinococcus granulosus geminin 0.0347 0.2379 0.2378
Brugia malayi ecdysteroid receptor 0.0021 0.0046 0.0117
Leishmania major DNA polymerase eta, putative 0.002 0.0044 0.0035
Plasmodium falciparum transporter, putative 0.0043 0.0207 0.0616
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0033 0.0131 0.0406
Schistosoma mansoni hypothetical protein 0.0101 0.062 0.0619
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0717 0.1883
Echinococcus granulosus voltage gated potassium channel 0.0029 0.0107 0.0107
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0267 0.0265
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0023 0.0057
Leishmania major DNA polymerase kappa, putative 0.002 0.0044 0.0035
Echinococcus granulosus thioredoxin glutathione reductase 0.0465 0.322 0.3219
Loa Loa (eye worm) hypothetical protein 0.0055 0.0293 0.0769
Echinococcus multilocularis g-protein coupled receptor 0.0075 0.0435 0.0435
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.1735 0.3586
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0101 0.062 0.1925
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0044 0.0035
Loa Loa (eye worm) blistered cuticle protein 3 0.0072 0.0415 0.109
Mycobacterium ulcerans electron transfer protein FdxB 0.0022 0.0057 0.0054
Echinococcus multilocularis G-protein coupled receptor, putative 0.0075 0.0435 0.0435
Brugia malayi hypothetical protein 0.0075 0.0435 0.1116
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0038 0.0172 0.0165
Echinococcus granulosus g protein coupled receptor 0.0075 0.0435 0.0435
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0046 0.0046
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0016 0.001 0.0009
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0044 0.0136
Echinococcus multilocularis thioredoxin glutathione reductase 0.0465 0.322 0.3219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0119 0.0235
Echinococcus granulosus lamin 0.0055 0.0293 0.0293
Plasmodium falciparum thioredoxin reductase 0.038 0.2617 0.8121
Echinococcus granulosus orexin receptor type 2 0.0075 0.0435 0.0435
Brugia malayi Egg laying defective protein 4 0.0016 0.001 0.0023
Schistosoma mansoni cpg binding protein 0.0032 0.0129 0.0128
Loa Loa (eye worm) hypothetical protein 0.0043 0.0207 0.0544
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0368 0.0367
Schistosoma mansoni loxhd1 0.004 0.0187 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0254 0.0514
Echinococcus granulosus histone lysine methyltransferase setb 0.008 0.0468 0.0468
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0267 0.0781
Trypanosoma cruzi trypanothione reductase, putative 0.0465 0.322 0.3345
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0101 0.062 0.2251
Echinococcus multilocularis musashi 0.0055 0.0293 0.0293
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0044 0.0012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0082 0.0213
Echinococcus multilocularis hyperpolarization activated cyclic 0.0022 0.0058 0.0057
Brugia malayi hypothetical protein 0.0075 0.0435 0.1116
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.015 0.0973 0.3023
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0044 0.0031
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0017 0.0024
Trichomonas vaginalis xanthine dehydrogenase, putative 0.069 0.4826 1
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0153 0.0992 0.1021
Plasmodium falciparum amino acid transporter, putative 0.0043 0.0207 0.0616
Trypanosoma cruzi trypanothione reductase, putative 0.038 0.2617 0.2716
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0092 0.0556 0.0556
Entamoeba histolytica hypothetical protein 0.0098 0.0602 0.2466
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0095 0.0575 0.0574
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0101 0.062 0.1857
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.004 0.0182 0.0181
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0119 0.0236
Loa Loa (eye worm) SRC-1 0.004 0.0182 0.0477
Echinococcus multilocularis conserved hypothetical protein 0.0727 0.5093 0.5093
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.001 0.001
Echinococcus granulosus tyrosine protein kinase Blk 0.0036 0.0154 0.0154
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0717 0.1475
Onchocerca volvulus 0.0486 0.3371 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0388 0.0792
Loa Loa (eye worm) hypothetical protein 0.0054 0.0286 0.075
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0038 0.017 0.034
Echinococcus multilocularis somatostatin receptor 0.0075 0.0435 0.0435
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0368 0.0942
Giardia lamblia NADH oxidase lateral transfer candidate 0.038 0.2617 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0207 0.0544
Echinococcus granulosus neuropeptide receptor A26 0.0533 0.3706 0.3706
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0017 0.0017
Echinococcus granulosus alpha 1A adrenergic receptor 0.0075 0.0435 0.0435
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0717 0.0734
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0033 0.0131 0.0291
Onchocerca volvulus 0.0075 0.0435 0.129
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0038 0.017 0.0498
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.011 0.0287
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0435 0.1144
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0046 0.0046
Echinococcus granulosus 7tm_1 domain containing protein 0.0075 0.0435 0.0435
Schistosoma mansoni cellular tumor antigen P53 0.0101 0.0622 0.0622
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0101 0.062 0.0619
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.038 0.2617 0.2716
Schistosoma mansoni lamin 0.0055 0.0293 0.0293
Trichomonas vaginalis ap endonuclease, putative 0.002 0.004 0.0071
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.011 0.028
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0279 0.1895 0.486
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0233 0.1562 0.4874
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0141 0.0133
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0368 0.0373
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0046 0.0117
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.038 0.2617 0.8121
Toxoplasma gondii exonuclease III APE 0.002 0.004 0.0094
Toxoplasma gondii hypothetical protein 0.0043 0.0207 0.0616
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0022 0.0057 0.0056
Echinococcus multilocularis zinc finger protein 0.0022 0.0057 0.0057
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0101 0.062 0.0619
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0101 0.062 0.0619
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0101 0.062 0.1901
Leishmania major phosphatidylinositol 3-kinase, putative 0.0031 0.0119 0.0114
Schistosoma mansoni neuropeptide receptor 0.0075 0.0435 0.0435
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0017 0.0043
Echinococcus granulosus serine protein kinase ATM 0.0017 0.0023 0.0022
Plasmodium vivax glutathione reductase, putative 0.0465 0.322 1
Chlamydia trachomatis endonuclease IV 0.0076 0.0443 0.151
Schistosoma mansoni bromodomain containing protein 0.0068 0.0386 0.0386
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0388 0.267 0.2772
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0187 0.0186
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Onchocerca volvulus 0.0101 0.062 0.1837
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0031 0.0081
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0075 0.0435 0.0435
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0387 0.2662 0.2662
Loa Loa (eye worm) hypothetical protein 0.0101 0.062 0.1629
Onchocerca volvulus 0.0101 0.0622 0.1845
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0119 0.0236
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0291 0.0593
Loa Loa (eye worm) hypothetical protein 0.0026 0.0082 0.0213
Mycobacterium tuberculosis Probable oxidoreductase 0.0022 0.0057 0.0176
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0187 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0556 0.1142
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0038 0.017 0.0445
Schistosoma mansoni glutamate synthase 0.0101 0.062 0.0619
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0044 0.0136
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0083 0.0491 0.1257
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0009 0.0007
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0101 0.062 0.1629
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0033 0.0131 0.0406
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0046 0.0046
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0948 0.667 0.6669
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0046 0.0117
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0075 0.0435 0.0435
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0101 0.062 0.1274
Onchocerca volvulus 0.0075 0.0435 0.129
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0017 0.0004
Echinococcus granulosus transcription factor Dp 1 0.0038 0.017 0.0169
Schistosoma mansoni neuropeptide receptor 0.0075 0.0435 0.0435
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.0057 0.0049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0046 0.012
Trypanosoma cruzi cytochrome P450, putative 0.005 0.0259 0.0256
Schistosoma mansoni hypothetical protein 0.0023 0.0064 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0388 0.0792
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0161 0.0323
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0207 0.0616
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0022 0.0058 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0422 0.0863
Schistosoma mansoni neuropeptide receptor 0.0075 0.0435 0.0435
Echinococcus multilocularis tyrosine protein kinase Srms 0.0036 0.0154 0.0154
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0717 0.2956
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Brugia malayi putative neuropeptide receptor NPR1 0.0075 0.0435 0.1116
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0154 0.0154
Echinococcus granulosus mitogen activated protein kinase 0.0105 0.0648 0.0648
Trypanosoma brucei trypanothione reductase 0.0465 0.322 0.3345
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0435 0.0435
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0101 0.062 0.2544
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0113
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0022 0.0058 0.0057
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0435 0.0435
Brugia malayi CXXC zinc finger family protein 0.0029 0.0103 0.0262
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0033 0.0131 0.0291
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0435 0.0435
Loa Loa (eye worm) cytochrome P450 family protein 0.005 0.0259 0.068
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0046 0.0117
Loa Loa (eye worm) hypothetical protein 0.0511 0.3553 0.9342
Onchocerca volvulus 0.0075 0.0435 0.129
Mycobacterium ulcerans oxygenase 0.0022 0.0057 0.0054
Trichomonas vaginalis mercuric reductase, putative 0.038 0.2617 0.5416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0036
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0033 0.0131 0.0291
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0038 0.017 0.0163
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0161 0.0154
Echinococcus granulosus tumor protein p63 0.0692 0.4845 0.4844
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0075 0.0435 0.1116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0435 0.0435
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0027 0.0026
Schistosoma mansoni fkbp-rapamycin associated protein 0.0017 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Trichomonas vaginalis Ferredoxin 6 0.0022 0.0057 0.0106
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0038 0.017 0.0476
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0161 0.0161
Treponema pallidum fructose-bisphosphate aldolase 0.0308 0.2099 0.799
Echinococcus granulosus tyrosine protein kinase HCK 0.0032 0.0126 0.0125
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0105 0.0648 0.1703
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0388 0.267 0.6849
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0046 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0648 0.0648
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0435 0.0435
Echinococcus granulosus sex peptide receptor 0.0075 0.0435 0.0435
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0001 0.000000048638
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0075 0.0435 0.1144
Mycobacterium ulcerans dehydrogenase 0.0101 0.062 0.1857
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0046 0.012
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0101 0.062 0.1901
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.004 0.0028
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.004 0.0071
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0207 0.0207
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0033 0.0131 0.0291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0119 0.0235
Mycobacterium ulcerans hypothetical protein 0.0112 0.0699 0.2112
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.038 0.2617 1
Brugia malayi hypothetical protein 0.0075 0.0435 0.1116
Loa Loa (eye worm) hypothetical protein 0.0107 0.0661 0.1736
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0717 0.2956
Brugia malayi PHD-finger family protein 0.0028 0.0098 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0253 0.0513
Plasmodium vivax ferrodoxin reductase, putative 0.0101 0.062 0.1882
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0119 0.0342
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0031
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0717 0.1475
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0043 0.0207 0.0207
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0092 0.0556 0.057
Brugia malayi 6-phosphofructokinase 0.0115 0.0718 0.1839
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0046 0.0117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.2099 0.4342
Plasmodium falciparum glutathione reductase 0.0465 0.322 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0075 0.0435 0.0435
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.004 0.0032
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0119 0.0236
Schistosoma mansoni hypothetical protein 0.0407 0.2807 0.2806
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0044 0.0079
Schistosoma mansoni coup transcription factor 0.0021 0.0046 0.0046
Treponema pallidum thioredoxin reductase (trxB) 0.0101 0.062 0.2251
Onchocerca volvulus 0.0055 0.0293 0.0868
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0022 0.0057 0.0045
Loa Loa (eye worm) hypothetical protein 0.0052 0.0267 0.0702
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0161 0.0161
Schistosoma mansoni voltage-gated potassium channel 0.009 0.054 0.054
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0257 0.1735 0.4561
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0029 0.0107 0.0273
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0648 0.1333
Echinococcus multilocularis serotonin receptor 0.0203 0.1352 0.1352
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0999 0.7034 0.7325
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0017 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0435 0.0435
Echinococcus multilocularis tyrosine protein kinase Src42A 0.004 0.0182 0.0181
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0119 0.0236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0556 0.1142
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.1735 0.3586
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0319 0.0319
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0457 0.3163 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0044 0.0113
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0022 0.0057 0.0054
Schistosoma mansoni hypothetical protein 0.0347 0.2379 0.2378
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1168 0.2411
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0293 0.0769
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0119 0.0235
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0101 0.062 0.2251
Loa Loa (eye worm) hypothetical protein 0.0053 0.0274 0.0718
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0022 0.0058 0.0057
Treponema pallidum quinoline 2-oxidoreductase 0.011 0.0681 0.2487
Brugia malayi Blistered cuticle protein 3 0.0072 0.0415 0.1063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.2099 0.4342
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.02 0.1329 0.394
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0038 0.017 0.0169
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0044 0.0031
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0046 0.0046
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0346 0.237 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0084
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0044 0.0031
Toxoplasma gondii cytochrome p450 superfamily protein 0.0033 0.0131 0.0377
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0105 0.0648 0.0662
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0083 0.0491 0.1289
Onchocerca volvulus 0.0043 0.0207 0.0614
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0443 0.1351
Brugia malayi Death domain containing protein 0.0014 0.0001 0.00000012476
Echinococcus granulosus G protein coupled receptor 139 0.0075 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0511 0.3553 0.9342
Echinococcus granulosus GPCR family 2 0.0017 0.0017 0.0017
Echinococcus multilocularis orexin receptor type 2 0.0075 0.0435 0.0435
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.015 0.0973 0.3618
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0031
Echinococcus granulosus glutamate synthase 0.0101 0.062 0.0619
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0075 0.0435 0.0435
Brugia malayi glutamate synthase 0.0101 0.062 0.1589
Trichomonas vaginalis xanthine dehydrogenase, putative 0.069 0.4826 1
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0043 0.0207 0.0207
Brugia malayi Cyclic-nucleotide gated cation channel 0.0022 0.0058 0.0146
Leishmania major hypothetical protein, conserved 0.0016 0.0014 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0009 0.0007
Schistosoma mansoni zinc finger protein 0.0022 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0036 0.0155 0.0406
Trypanosoma brucei C-8 sterol isomerase, putative 0.0388 0.267 0.2772
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0033 0.0131 0.0291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0291 0.0593
Brugia malayi cytochrome P450 0.0033 0.0131 0.0334
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0435 0.0435
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.2099 0.4342
Mycobacterium leprae Conserved hypothetical protein 0.0033 0.0131 0.0346
Echinococcus granulosus g protein coupled receptor 0.0075 0.0435 0.0435
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0031
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0087 0.0522 0.1337
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0075 0.0435 0.1116
Brugia malayi ORL1-like opioid receptor 0.0075 0.0435 0.1116
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0017 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.062 0.0633
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0435 0.0435
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.0193 0.0192
Echinococcus granulosus tyrosine kinase 0.0036 0.0154 0.0154
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0022 0.0058 0.0057
Mycobacterium ulcerans oxidoreductase 0.0022 0.0057 0.0054
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0101 0.062 0.1857
Brugia malayi Dopamine receptor protein 2 0.0075 0.0435 0.1116
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0036 0.0154 0.0154
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0187 0.0552
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0016 0.0015 0.0014
Echinococcus granulosus mitogen activated protein kinase 3 0.0105 0.0648 0.0648
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0042 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0253 0.0513
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0031
Schistosoma mansoni hypothetical protein 0.0087 0.0522 0.0521
Brugia malayi neuropeptide F receptor 0.0075 0.0435 0.1116
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1143 0.8062 0.8398
Brugia malayi CHD4 protein 0.0016 0.001 0.0025
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0443 0.133
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.038 0.2617 0.2716
Schistosoma mansoni sulfide quinone reductase 0.0101 0.062 0.0619
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0101 0.062 0.1274
Trichomonas vaginalis glutathione reductase, putative 0.038 0.2617 0.5416
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.003 0.0051
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0207 0.0616
Schistosoma mansoni lipoxygenase 0.0169 0.1105 0.1105
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0422 0.0421
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0293 0.0769
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0033 0.0131 0.0291
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0022 0.0057 0.0144
Onchocerca volvulus 0.0075 0.0435 0.129
Echinococcus granulosus cpg binding protein 0.0032 0.0129 0.0128
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0161 0.0161
Trichomonas vaginalis Ferredoxin 2 0.0022 0.0057 0.0106
Schistosoma mansoni opsin-like receptor 0.0075 0.0435 0.0435
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0101 0.062 0.1925
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0101 0.062 0.1589
Echinococcus multilocularis neuropeptide s receptor 0.0533 0.3706 0.3706
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0435 0.0435
Schistosoma mansoni amine GPCR 0.0075 0.0435 0.0435
Mycobacterium ulcerans electron transfer protein 0.0022 0.0057 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0046 0.012
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0046 0.0046
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0092 0.0556 0.0566
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0207 0.0207
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0044 0.0209 0.0204
Entamoeba histolytica protein kinase, putative 0.0032 0.0126 0.0439
Loa Loa (eye worm) programmed cell death 8 0.0101 0.062 0.1629
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0046 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.001 0.0009
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0046 0.0046
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0368 0.0367
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0119 0.0245
Brugia malayi hypothetical protein 0.0075 0.0435 0.1116
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0027 0.0026
Onchocerca volvulus 0.0255 0.1719 0.5097
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.004 0.0028
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0038 0.017 0.0498
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.008 0.0468 0.0468
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0017 0.0023 0.001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0023 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1103 0.2277
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0087 0.0522 0.0521
Loa Loa (eye worm) hypothetical protein 0.0484 0.336 0.8835
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0033 0.0131 0.0406
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0648 0.1333
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.0468 0.0468
Echinococcus multilocularis tyrosine protein kinase Fgr 0.004 0.0182 0.0181
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.004 0.0182 0.0181
Brugia malayi protein-tyrosine kinase 0.0036 0.0154 0.0394
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0046 0.012
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0648 0.1333
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0207 0.0207
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0161 0.0161
Brugia malayi hypothetical protein 0.004 0.0187 0.0478
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0017 0.0023 0.001
Schistosoma mansoni hypothetical protein 0.0075 0.0435 0.0435
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0046 0.0046
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0089 0.0088
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0075 0.0432 0.0885
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.2099 0.4342
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0046 0.0136
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0254 0.0514
Echinococcus granulosus intermediate filament protein 0.0055 0.0293 0.0293
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0422 0.0863
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0119 0.0319
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0717 0.1475
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.012
Onchocerca volvulus Glucosylceramidase homolog 0.0169 0.1103 0.3271
Onchocerca volvulus 0.0055 0.0293 0.0868
Onchocerca volvulus 0.0107 0.0661 0.1959
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0022 0.0057 0.0147
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0038 0.017 0.034
Onchocerca volvulus 0.0075 0.0435 0.129
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.0443 0.1136
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0022 0.0057 0.0144
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0046 0.012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0999 0.7034 0.7325
Chlamydia trachomatis thioredoxin reductase 0.0101 0.062 0.22
Brugia malayi hypothetical protein 0.0075 0.0435 0.1116
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0058 0.0057
Schistosoma mansoni adrenodoxin 0.0022 0.0057 0.0056
Toxoplasma gondii ferredoxin, putative 0.0022 0.0057 0.0147
Echinococcus multilocularis tumor protein p63 0.0692 0.4845 0.4844
Schistosoma mansoni sulfide quinone reductase 0.0101 0.062 0.0619
Brugia malayi P38 map kinase family protein 2 0.0153 0.0992 0.2542
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0267 0.0265
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.1735 0.3586
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0038 0.017 0.0625
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0169 0.0168
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0717 0.2621
Brugia malayi larval opioid receptor 0.0075 0.0435 0.1116
Onchocerca volvulus 0.0043 0.0207 0.0614
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0101 0.062 0.1857
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0022 0.0057 0.0147
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0101 0.062 0.2245
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0207 0.0207
Mycobacterium ulcerans oxidoreductase 0.0022 0.0057 0.0054
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0717 0.0737
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0101 0.062 0.1274
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.015
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0046 0.0117
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0161 0.059
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0207 0.0544
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.038 0.2617 0.2616
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0435 0.0435
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0033 0.0131 0.0406
Trypanosoma brucei protein kinase, putative 0.0105 0.0648 0.0662
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.001 0.0009
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0435 0.0435
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0119 0.0412
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0233 0.1562 0.4874
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0648 0.1333
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0033 0.0131 0.0291
Onchocerca volvulus 0.0075 0.0435 0.129
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0717 0.0716
Giardia lamblia Glutamate synthase 0.0101 0.062 0.2251
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0101 0.062 0.1274
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1358 0.9597 1
Onchocerca volvulus 0.0043 0.0207 0.0614
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0043
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0075 0.0435 0.0435
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0046 0.0117
Treponema pallidum sodium- and chloride- dependent transporter 0.0255 0.1719 0.6515
Echinococcus granulosus g-protein coupled receptor 0.0075 0.0435 0.0435
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0153 0.0992 0.2607
Onchocerca volvulus 0.0075 0.0435 0.129
Echinococcus granulosus peptide allatostatin:somatostatin 0.0075 0.0435 0.0435
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0119 0.0236
Brugia malayi follicle stimulating hormone receptor 0.0546 0.3803 0.9753
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0075 0.0435 0.0435
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0033 0.0131 0.0406
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0075 0.0435 0.0435
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0058 0.0057
Loa Loa (eye worm) hypothetical protein 0.0075 0.0431 0.1131
Leishmania major cytochrome p450-like protein 0.0033 0.0131 0.0126
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0022 0.0058 0.0057
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0153 0.0992 0.1021
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0717 0.0716
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0033 0.0131 0.0406
Onchocerca volvulus Dual oxidase homolog 0.0072 0.0415 0.1229
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0101 0.062 0.2245
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0044 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0046 0.0117
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.038 0.2617 0.8127
Onchocerca volvulus 0.0075 0.0435 0.129
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0046 0.0046
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0017 0.0024
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0717 0.2167
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0043 0.0207 0.0207
Loa Loa (eye worm) TK protein kinase 0.0032 0.0126 0.0329
Treponema pallidum oxidoreductase 0.0101 0.062 0.2251
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0288 0.0585
Plasmodium vivax amine transporter, putative 0.0043 0.0207 0.0593
Echinococcus multilocularis dna polymerase eta 0.002 0.0044 0.0043
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.0087 0.0522 0.1371
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0717 0.2226
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0101 0.062 0.1901
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0435 0.0435
Trypanosoma brucei cytochrome P450, putative 0.005 0.0259 0.0256
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.008 0.0079
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0101 0.062 0.0619
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1103 0.2277
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0359 0.0359
Echinococcus multilocularis expressed conserved protein 0.0016 0.001 0.0009
Echinococcus multilocularis mitogen activated protein kinase 14 0.0153 0.0992 0.0991
Brugia malayi Serotonin receptor 0.056 0.3899 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.0068 0.0388 0.1177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0388 0.0792
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0119 0.0245
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0046 0.0117
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0033 0.0131 0.0291
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0046 0.0046
Trichomonas vaginalis apoptosis inducing factor, putative 0.0101 0.062 0.1274
Giardia lamblia Fructose-bisphosphate aldolase 0.0308 0.2099 0.799
Brugia malayi 6-phosphofructokinase 0.0115 0.0717 0.1837
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0207 0.053
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0435 0.0435
Plasmodium falciparum glutathione reductase 0.038 0.2617 0.8121
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0087 0.0522 0.0521
Echinococcus multilocularis dro:myosuppressin receptor 0.0075 0.0435 0.0435
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0267 0.0802
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0001 0.0001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.004 0.0187 0.049
Trichomonas vaginalis Ferredoxin 1 0.0022 0.0057 0.0106
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0274 0.07
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0073 0.0422 0.043
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0033 0.0131 0.0291
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0044 0.0043
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.004 0.0028
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0031 0.0119 0.0118
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0042 0.0129
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0046 0.0046
Schistosoma mansoni tyrosine kinase 0.004 0.0182 0.0181
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0089 0.0088
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0107 0.0107
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0387 0.2662 0.6827
Loa Loa (eye worm) TK protein kinase 0.0036 0.0154 0.0404
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0033 0.0131 0.0406
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0016 0.001 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.2099 0.4342
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0161 0.0161
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0435 0.0435
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0101 0.062 0.0633
Echinococcus granulosus hyperpolarization activated cyclic 0.0022 0.0058 0.0057
Echinococcus granulosus tachykinin peptides receptor 99D 0.0075 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Schistosoma mansoni survival motor neuron protein 0.0099 0.0604 0.0604
Trichomonas vaginalis glutamate synthase, putative 0.0101 0.062 0.1274
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0017 0.0017
Leishmania major ferredoxin, 2fe-2s-like protein 0.0022 0.0057 0.0049
Echinococcus granulosus neuropeptide FF receptor 2 0.0075 0.0435 0.0435
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0267 0.0802
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0161 0.0161
Brugia malayi hypothetical protein 0.0075 0.0435 0.1116
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0075 0.0435 0.1144
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0044 0.0031
Echinococcus granulosus fmrfamide receptor 0.0075 0.0435 0.0435
Schistosoma mansoni ap endonuclease 0.002 0.004 0.0039
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0033 0.0131 0.0291
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0101 0.062 0.1882
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.0443 0.1377
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0092 0.0556 0.0566
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0033 0.0131 0.0291
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Loa Loa (eye worm) hypothetical protein 0.0027 0.0089 0.0232
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0075 0.0435 0.0435
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0043 0.0207 0.0207
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0044 0.011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.038 0.2617 0.2716
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.004 0.0124
Loa Loa (eye worm) solute carrier family 6 member 4 0.0255 0.1719 0.4519
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0368 0.1469
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.2807 0.2806
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0044 0.011
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0207 0.0207
Schistosoma mansoni amine GPCR 0.0424 0.2929 0.2929
Brugia malayi M-phase phosphoprotein, mpp8 0.0107 0.0661 0.1694
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0046 0.0117
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0435 0.0435
Brugia malayi neuropeptide F receptor 0.0075 0.0435 0.1116
Schistosoma mansoni hypothetical protein 0.0087 0.0522 0.0521
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0435 0.0435
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0161 0.0161
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0092 0.0556 0.2272
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0101 0.062 0.2251
Echinococcus granulosus lamin dm0 0.0055 0.0293 0.0293
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0087 0.0522 0.0521
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0368 0.0966
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0075 0.0435 0.0435
Schistosoma mansoni sodium/chloride dependent transporter 0.0045 0.0218 0.0218
Brugia malayi Dopamine receptor 0.0075 0.0435 0.1116
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0073 0.0422 0.0426
Onchocerca volvulus 0.0075 0.0435 0.129
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0038 0.017 0.0434
Mycobacterium ulcerans monoxygenase 0.0101 0.062 0.1857
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0435 0.0435
Onchocerca volvulus 0.0029 0.0103 0.0303
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0017 0.0017
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.004 0.0073
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0033 0.0131 0.0122
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0207 0.0207
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0092 0.0556 0.0566
Schistosoma mansoni hypothetical protein 0.004 0.0187 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0388 0.0792
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0033 0.0131 0.0291
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.038 0.2617 0.2616
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0435 0.0435
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.038 0.2617 1
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0119 0.0236
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0101 0.062 0.1274
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0022 0.0057 0.0176
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0119 0.011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1143 0.8062 0.8398
Echinococcus granulosus allatostatin A receptor 0.0075 0.0435 0.0435
Echinococcus granulosus somatostatin receptor 0.0075 0.0435 0.0435
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0031
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.004 0.0104
Giardia lamblia DNA repair protein RAD52 0.0346 0.237 0.9043
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.004 0.0182 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0388 0.0792
Echinococcus multilocularis sex peptide receptor 0.0075 0.0435 0.0435
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0046 0.0117
Schistosoma mansoni sodium/chloride dependent transporter 0.0043 0.0207 0.0207
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0042 0.0006
Echinococcus granulosus neuropeptide s receptor 0.0533 0.3706 0.3706
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0095 0.0575 0.0574
Schistosoma mansoni disulfide oxidoreductase 0.0101 0.062 0.0619
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0101 0.062 0.0619
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0101 0.062 0.1274
Loa Loa (eye worm) glutathione reductase 0.0465 0.322 0.8467
Echinococcus multilocularis serotonin receptor 0.0203 0.1352 0.1352
Trypanosoma cruzi cytochrome P450, putative 0.005 0.0259 0.0256
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0075 0.0435 0.1144
Schistosoma mansoni cytochrome P450 0.0033 0.0131 0.013
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0101 0.062 0.0633
Echinococcus granulosus mitogen activated protein kinase 11 0.0153 0.0992 0.0991
Loa Loa (eye worm) serotonin transporter b 0.0255 0.1719 0.4519
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0101 0.062 0.0619
Brugia malayi putative neuropeptide receptor 0.0075 0.0435 0.1116
Brugia malayi hypothetical protein 0.004 0.0187 0.0478
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0435 0.0435
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0033 0.0131 0.0122
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0101 0.062 0.1857
Echinococcus multilocularis voltage gated potassium channel 0.0029 0.0107 0.0107
Echinococcus granulosus biogenic amine 5HT receptor 0.045 0.3112 0.3111
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.038 0.2617 0.8117
Leishmania major hypothetical protein, conserved 0.0101 0.062 0.0636
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0076 0.0443 0.1164
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0207 0.053
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.0182 0.0181
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0105 0.0648 0.0662
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0717 0.0716
Loa Loa (eye worm) apoptosis regulator protein 0.0087 0.0522 0.1371
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.003 0.0051
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0083 0.0491 0.049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0288 0.0585
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0017 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0044 0.0031
Loa Loa (eye worm) phosphatidylinositol 3 0.0092 0.0556 0.1461
Echinococcus granulosus Adrenodoxin mitochondrial 0.0022 0.0057 0.0056
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0017 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0057 0.0045
Brugia malayi intermediate filament protein 0.0055 0.0293 0.075
Echinococcus granulosus neuropeptide receptor 0.0075 0.0435 0.0435
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0105 0.0648 0.1989
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0105 0.0648 0.0662
Brugia malayi Bromodomain containing protein 0.004 0.0187 0.0477
Toxoplasma gondii NADPH-glutathione reductase 0.038 0.2617 0.8121
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0101 0.062 0.1925
Giardia lamblia DINP protein human, muc B family 0.002 0.0044 0.0014
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0017 0.0017
Loa Loa (eye worm) TYRA-2 protein 0.0075 0.0435 0.1144
Echinococcus multilocularis mitogen activated protein kinase 11 0.0153 0.0992 0.0991
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.038 0.2617 0.6711
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0031 0.0119 0.0118
Treponema pallidum hypothetical protein 0.0092 0.0558 0.2011
Brugia malayi Protein kinase domain containing protein 0.0016 0.0011 0.0028
Echinococcus multilocularis biogenic amine (5HT) receptor 0.045 0.3112 0.3111
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0058 0.0057
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.038 0.2617 0.8121
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0435 0.0435
Schistosoma mansoni hypothetical protein 0.0099 0.0604 0.0604
Echinococcus multilocularis Ankyrin 0.0014 0.0001 0.0001
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.017 0.0169
Echinococcus multilocularis mitogen activated protein kinase 11 0.0153 0.0992 0.0991
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0017 0.0017
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0105 0.0648 0.0666
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.0057 0.0049
Schistosoma mansoni histamine h1 receptor 0.0075 0.0435 0.0435
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0435 0.1144
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0255 0.1719 0.1718
Schistosoma mansoni sodium/chloride dependent transporter 0.0255 0.1719 0.1718
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0101 0.062 0.0619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0291 0.0593
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0101 0.062 0.0619
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0017 0.0042
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.038 0.2617 1
Onchocerca volvulus 0.0075 0.0435 0.129
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0187 0.0186
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0033 0.0131 0.0122
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Echinococcus granulosus RUN 0.004 0.0187 0.0186
Brugia malayi hypothetical protein 0.0075 0.0435 0.1116
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0169 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0046 0.0117
Loa Loa (eye worm) hypothetical protein 0.0388 0.267 0.7022
Leishmania major ferric reductase, putative 0.0034 0.0141 0.0137
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0038 0.017 0.0445
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0101 0.062 0.1901
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0119 0.0342
Loa Loa (eye worm) hypothetical protein 0.02 0.1329 0.3493
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.2099 0.4342
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0308 0.2099 0.8844
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0435 0.0435
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0033 0.0131 0.0406
Echinococcus multilocularis neuropeptide receptor A26 0.0533 0.3706 0.3706
Brugia malayi MAP kinase sur-1 0.0105 0.0648 0.1661
Schistosoma mansoni biogenic amine receptor 0.0075 0.0435 0.0435
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0435 0.0435
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0717 0.2956
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0033 0.0131 0.0126
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0046 0.0046
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0101 0.062 0.0633
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.004 0.0182 0.0181
Brugia malayi Dopamine receptor protein 1 0.0075 0.0435 0.1116
Echinococcus multilocularis mitogen activated protein kinase 3 0.0105 0.0648 0.0648
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0046 0.0046
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0101 0.062 0.0633
Toxoplasma gondii thioredoxin reductase 0.0465 0.322 1
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0132 0.0839 0.2606
Loa Loa (eye worm) hypothetical protein 0.0198 0.1315 0.3458
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0119 0.0236
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0435 0.0435
Loa Loa (eye worm) thioredoxin reductase 0.0465 0.322 0.8467
Echinococcus granulosus dna polymerase eta 0.002 0.0044 0.0043
Echinococcus granulosus cytochrome P450 2K1 0.0033 0.0131 0.013
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0101 0.062 0.0636
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0267 0.0802
Brugia malayi N-terminal motif family protein 0.02 0.1329 0.3407
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0022 0.0058 0.0108
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0092 0.0556 0.0556
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.012
Brugia malayi phosphofructokinase 0.0115 0.0717 0.1837
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1103 0.2277
Brugia malayi hypothetical protein 0.0484 0.336 0.8617
Echinococcus granulosus dnaJ subfamily B 0.0407 0.2807 0.2806
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0022 0.0057 0.0167
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0207 0.0207
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0017 0.0023 0.0022
Trichomonas vaginalis ap endonuclease, putative 0.002 0.004 0.0071
Echinococcus multilocularis RUN 0.004 0.0187 0.0186
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Echinococcus multilocularis GPCR, family 2 0.0017 0.0017 0.0017
Trichomonas vaginalis Ferredoxin 7 0.0022 0.0057 0.0106
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0325 0.2222 0.6987
Brugia malayi Serotonin receptor 0.0075 0.0435 0.1116
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0017 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0325 0.0663
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0043 0.0207 0.0544
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.038 0.2617 0.8121
Loa Loa (eye worm) phosphatidylinositol 3 0.0031 0.0119 0.0311
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0022 0.0058 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0033 0.0131 0.0406
Onchocerca volvulus 0.0075 0.0435 0.129
Treponema pallidum hypothetical protein 0.0112 0.0699 0.2559
Echinococcus multilocularis geminin 0.0347 0.2379 0.2378
Mycobacterium tuberculosis Probable oxidoreductase 0.038 0.2617 0.8127
Mycobacterium ulcerans flavoprotein disulfide reductase 0.038 0.2617 0.8252
Schistosoma mansoni opsin-like receptor 0.0075 0.0435 0.0435
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0101 0.062 0.2544
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0101 0.062 0.1857
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Plasmodium falciparum ferredoxin, putative 0.0022 0.0057 0.0147
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0046 0.0136
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0319 0.0964
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0101 0.062 0.2544
Leishmania major ferredoxin 2fe-2s-like protein 0.0022 0.0057 0.0049
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0101 0.062 0.1901
Brugia malayi hypothetical protein 0.0107 0.0662 0.1696
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Onchocerca volvulus 0.0075 0.0435 0.129
Brugia malayi GnHR receptor homolog 0.0075 0.0435 0.1116
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0107 0.0107
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0044 0.0031
Echinococcus granulosus biogenic amine 5HT receptor 0.0203 0.1352 0.1352
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.003 0.0051
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0043 0.0207 0.0207
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0017 0.0004
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0207 0.0616
Brugia malayi hypothetical protein 0.0075 0.0435 0.1116
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1168 0.2411
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0435 0.0435
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0101 0.062 0.2544
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0038 0.017 0.0169
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0101 0.062 0.0619
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0207 0.0207
Brugia malayi Cytochrome P450 family protein 0.0091 0.0546 0.1398
Schistosoma mansoni rab6-interacting 0.004 0.0187 0.0186
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0033 0.0131 0.0406
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0717 0.0716
Echinococcus granulosus serotonin receptor 0.0075 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0387 0.2662 0.7
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0031 0.0119 0.011
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.062 0.0633
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0075 0.0435 0.1116
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0031 0.0119 0.011
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0207 0.053
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0435 0.0435
Echinococcus multilocularis hyperpolarization activated cyclic 0.0022 0.0058 0.0057
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0033 0.0131 0.0291
Loa Loa (eye worm) hypothetical protein 0.0387 0.2662 0.7
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0022 0.0057 0.0176
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.0468 0.0468
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0255 0.1719 0.4407
Schistosoma mansoni hypothetical protein 0.0016 0.0014 0.0013
Echinococcus multilocularis allatostatin A receptor 0.0075 0.0435 0.0435
Schistosoma mansoni polycystin 1-related 0.004 0.0187 0.0186
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0046 0.0046
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0267 0.0265
Schistosoma mansoni hypothetical protein 0.0033 0.0131 0.013
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0604 0.1549
Echinococcus multilocularis microtubule associated protein 2 0.1414 1 1
Schistosoma mansoni neuropeptide receptor 0.0075 0.0435 0.0435
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0092 0.0556 0.057
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.001 0.0025
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0101 0.062 0.1882
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0207 0.0544
Onchocerca volvulus 0.0075 0.0435 0.129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0435 0.0435
Brugia malayi AKH receptor 0.0075 0.0435 0.1116
Loa Loa (eye worm) hypothetical protein 0.004 0.0187 0.0491
Brugia malayi sulfakinin receptor protein 0.0075 0.0435 0.1116
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0075 0.0435 0.1144
Brugia malayi nuclear hormone receptor 0.0021 0.0046 0.0117
Brugia malayi nuclear receptor NHR-88 0.0021 0.0046 0.0117
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0717 0.1883
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0207 0.0207
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0031 0.0119 0.0114
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0207 0.0593
Echinococcus multilocularis tyrosine protein kinase Blk 0.0036 0.0154 0.0154
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.003 0.0051
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0187 0.0186
Trypanosoma cruzi target of rapamycin kinase 3 0.0073 0.0422 0.0426
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0119 0.0235
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.012
Loa Loa (eye worm) cytochrome P450 0.0033 0.0131 0.0342
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0257 0.1735 0.4448
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0101 0.062 0.1925
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0033 0.0131 0.0406
Echinococcus granulosus zinc finger protein 0.0022 0.0057 0.0057
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.004 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0046 0.0117
Schistosoma mansoni amine GPCR 0.0075 0.0435 0.0435
Echinococcus multilocularis neuropeptide FF receptor 2 0.0075 0.0435 0.0435
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0101 0.062 0.2245
Toxoplasma gondii ferodoxin FD 0.0022 0.0057 0.0147
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0033 0.0131 0.0406
Leishmania major hypothetical protein, conserved 0.0101 0.062 0.0636
Onchocerca volvulus 0.0075 0.0435 0.129
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0046 0.0117
Echinococcus granulosus cGMP dependent protein kinase 1 0.0016 0.001 0.0009
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0132 0.0839 0.256
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.003 0.0051
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0101 0.062 0.0633
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0033 0.0131 0.0291
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0182 0.0181
Trypanosoma brucei electron transfer protein, putative 0.0022 0.0057 0.0045
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.001 0.001
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0038 0.017 0.0169
Echinococcus granulosus hyperpolarization activated cyclic 0.0022 0.0058 0.0057

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 166 nM Inhibition of bacterially expressed p38alpha pretreated for 10 mins measured after 45 mins ChEMBL. 20804198

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.