Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IZ (functional) | = 24 mm | Antifungal activity Candida albicans ATCC 10231 after 48 hrs at 28 degC by agar diffusion technique | ChEMBL. | 19272782 |
IZ (functional) | = 31 mm | Antibacterial activity Escherichia coli ATCC 25922 after 24 hrs at 30 degC by agar diffusion technique | ChEMBL. | 19272782 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.