Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.007 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0071 | 0.0069 |
Onchocerca volvulus | 0.0028 | 0.0051 | 0.028 | |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0068 | 0.0007 |
Schistosoma mansoni | rab6-interacting | 0.0037 | 0.0071 | 0.0069 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0044 | 0.0089 | 0.0087 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0068 | 0.0066 |
Brugia malayi | calpain family protein 1 | 0.0063 | 0.0132 | 0.0131 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0066 | 0.014 | 0.0138 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0071 | 0.0069 |
Loa Loa (eye worm) | calpain | 0.0019 | 0.0029 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0132 | 0.0131 |
Brugia malayi | Doublecortin family protein | 0.0037 | 0.0071 | 0.0069 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0004 | 0.0003 |
Brugia malayi | thymidylate synthase | 0.0762 | 0.1761 | 0.1759 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0127 | 0.0282 | 0.028 |
Echinococcus granulosus | thymidylate synthase | 0.0762 | 0.1761 | 0.1759 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.007 | 0.0839 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0068 | 0.0818 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0127 | 0.0282 | 0.028 |
Echinococcus multilocularis | dihydrofolate reductase | 0.43 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.0141 | 0.014 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0068 | 0.0066 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.0265 | 0.1499 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0059 | 0.0058 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0243 | 0.0551 | 0.0549 |
Onchocerca volvulus | 0.0036 | 0.0068 | 0.0377 | |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0068 | 0.0007 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0004 | 0.0003 |
Echinococcus granulosus | muscleblind protein | 0.0147 | 0.0328 | 0.0327 |
Brugia malayi | hypothetical protein | 0.0363 | 0.083 | 0.0828 |
Brugia malayi | calpain family protein 1 | 0.0063 | 0.0132 | 0.0131 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0037 | 0.0071 | 0.0069 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.007 | 0.0068 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0068 | 0.0063 |
Schistosoma mansoni | rab6-interacting | 0.0037 | 0.0071 | 0.0069 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.007 | 0.0068 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0055 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0089 | 0.0087 |
Echinococcus granulosus | calpain A | 0.0066 | 0.014 | 0.0138 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0057 | 0.0056 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.0315 | 0.0314 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0004 | 0.0003 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0068 | 0.0007 |
Echinococcus multilocularis | muscleblind protein | 0.0147 | 0.0328 | 0.0327 |
Schistosoma mansoni | calpain (C02 family) | 0.0019 | 0.0029 | 0.0027 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0059 | 0.0058 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0055 | 0.0053 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.007 | 0.0066 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.007 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0059 | 0.0058 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0059 | 0.0058 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0227 | 0.0514 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0057 | 0.0056 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0068 | 0.0066 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0051 | 0.0049 |
Schistosoma mansoni | polycystin 1-related | 0.0037 | 0.0071 | 0.0069 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.43 | 1 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.007 | 0.0839 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.0315 | 0.0314 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0068 | 0.0007 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0142 | 0.0315 | 0.0314 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.007 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0059 | 0.0058 |
Trichomonas vaginalis | set domain proteins, putative | 0.0247 | 0.0562 | 0.6767 |
Echinococcus multilocularis | calpain | 0.0019 | 0.0029 | 0.0027 |
Onchocerca volvulus | 0.0036 | 0.0068 | 0.0377 | |
Echinococcus granulosus | calpain 7 C02 family | 0.0019 | 0.0029 | 0.0027 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0363 | 0.083 | 0.1293 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0068 | 0.0007 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0068 | 0.0007 |
Brugia malayi | calpain 5 | 0.0019 | 0.0029 | 0.0027 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.007 | 0.5 |
Onchocerca volvulus | 0.0762 | 0.1761 | 1 | |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0068 | 0.0007 |
Brugia malayi | follicle stimulating hormone receptor | 0.0243 | 0.0551 | 0.0549 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.0315 | 0.0314 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.0315 | 0.0314 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0057 | 0.0056 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0127 | 0.0126 |
Echinococcus granulosus | RUN | 0.0037 | 0.0071 | 0.0069 |
Loa Loa (eye worm) | thymidylate synthase | 0.0762 | 0.1761 | 0.1759 |
Echinococcus granulosus | calpain 5 | 0.0019 | 0.0029 | 0.0027 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0004 | 0.0003 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0057 | 0.0056 |
Onchocerca volvulus | 0.0032 | 0.0059 | 0.0327 | |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.2678 | 0.6222 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0068 | 0.0063 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.0282 | 0.028 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0071 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0068 | 0.0066 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0068 | 0.0063 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0059 | 0.0049 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0066 | 0.014 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0068 | 0.0066 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0098 | 0.0214 | 0.0212 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.007 | 0.0068 |
Schistosoma mansoni | calpain C (C02 family) | 0.0019 | 0.0029 | 0.0027 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0402 | 0.092 | 0.0919 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.0265 | 0.1499 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.007 | 0.0068 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0044 | 0.0089 | 0.0087 |
Onchocerca volvulus | 0.0044 | 0.0089 | 0.0495 | |
Echinococcus multilocularis | muscleblind protein 1 | 0.0147 | 0.0328 | 0.0327 |
Schistosoma mansoni | lipoxygenase | 0.0154 | 0.0343 | 0.0341 |
Loa Loa (eye worm) | TAR-binding protein | 0.0127 | 0.0282 | 0.028 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0141 | 0.014 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0068 | 0.0818 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0057 | 0.0056 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0037 | 0.0071 | 0.0067 |
Echinococcus multilocularis | calpain 5 | 0.0019 | 0.0029 | 0.0027 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0068 | 0.0818 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0068 | 0.0066 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0068 | 0.0066 |
Loa Loa (eye worm) | RNA binding protein | 0.0127 | 0.0282 | 0.028 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0055 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0328 | 0.0327 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0068 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0071 | 0.0069 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.0112 | 0.0086 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.43 | 1 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0059 | 0.0058 |
Brugia malayi | RNA binding protein | 0.0127 | 0.0282 | 0.028 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0057 | 0.0056 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0068 | 0.0818 |
Echinococcus granulosus | calpain A | 0.0019 | 0.0029 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0068 | 0.0066 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0762 | 0.1761 | 0.1759 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0068 | 0.0818 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0057 | 0.0056 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0051 | 0.0049 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0363 | 0.083 | 0.0774 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0141 | 0.014 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0057 | 0.0056 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0059 | 0.0058 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0068 | 0.0063 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0057 | 0.0056 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0037 | 0.0071 | 0.0069 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0762 | 0.1761 | 0.171 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0019 | 0.0029 | 0.0027 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.0282 | 0.028 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0071 | 0.0069 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0068 | 0.0063 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.007 | 0.0066 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0057 | 0.0056 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0037 | 0.0071 | 0.0069 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0762 | 0.1761 | 0.171 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0037 | 0.0071 | 0.0069 |
Schistosoma mansoni | lipoxygenase | 0.022 | 0.0497 | 0.0495 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0063 | 0.0132 | 0.0131 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.007 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0214 | 0.0212 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0068 | 0.0066 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0008 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0265 | 0.0264 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0098 | 0.0214 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0089 | 0.0087 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0068 | 0.0066 |
Echinococcus granulosus | tar DNA binding protein | 0.0127 | 0.0282 | 0.028 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0068 | 0.0007 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.2678 | 0.6222 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0055 | 0.0053 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0037 | 0.0071 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0265 | 0.0264 |
Echinococcus multilocularis | calpain 7 (C02 family) | 0.0019 | 0.0029 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0132 | 0.0131 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0057 | 0.0056 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0068 | 0.0014 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.007 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0068 | 0.0066 |
Echinococcus multilocularis | RUN | 0.0037 | 0.0071 | 0.0069 |
Mycobacterium ulcerans | thymidylate synthase | 0.0762 | 0.1761 | 0.1704 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.43 | 1 | 1 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.43 | 1 | 1 |
Schistosoma mansoni | dihydrofolate reductase | 0.43 | 1 | 1 |
Brugia malayi | Dihydrofolate reductase | 0.43 | 1 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0057 | 0.0056 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0059 | 0.0058 |
Loa Loa (eye worm) | calpain 5 | 0.0019 | 0.0029 | 0.0027 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0068 | 0.0007 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0218 | 0.0492 | 0.049 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0068 | 0.0007 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.007 | 0.0839 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0063 | 0.0132 | 0.0131 |
Brugia malayi | hypothetical protein | 0.012 | 0.0265 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0068 | 0.0066 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0019 | 0.0029 | 0.0027 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.2678 | 0.6222 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0057 | 0.0056 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0051 | 0.0049 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0068 | 0.0007 |
Brugia malayi | calpain 7 | 0.0019 | 0.0029 | 0.0027 |
Brugia malayi | Muscleblind-like protein | 0.0147 | 0.0328 | 0.0327 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0059 | 0.0058 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0055 | 0.0053 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0068 | 0.0066 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0098 | 0.0214 | 0.0212 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.0315 | 0.0314 |
Onchocerca volvulus | 0.0037 | 0.0071 | 0.0393 | |
Echinococcus multilocularis | thymidylate synthase | 0.0762 | 0.1761 | 0.1759 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0068 | 0.0818 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0363 | 0.083 | 1 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0066 | 0.014 | 0.0138 |
Brugia malayi | Inositol-1 | 0.0036 | 0.007 | 0.0068 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.0282 | 0.028 |
Brugia malayi | TAR-binding protein | 0.0127 | 0.0282 | 0.028 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0008 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0328 | 0.0327 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.007 | 0.0017 |
Schistosoma mansoni | Mername-AA248 (C02 family) | 0.0019 | 0.0029 | 0.0027 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0057 | 0.0056 |
Echinococcus multilocularis | tar DNA binding protein | 0.0127 | 0.0282 | 0.028 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0068 | 0.0066 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.022 | 0.0497 | 0.0495 |
Echinococcus granulosus | dnaJ subfamily B | 0.0402 | 0.092 | 0.0919 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0008 | 0.0007 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0823 | 0.1901 | 0.19 |
Onchocerca volvulus | 0.0036 | 0.0068 | 0.0377 | |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0004 | 0.0003 |
Loa Loa (eye worm) | doublecortin family protein | 0.0037 | 0.0071 | 0.0069 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.0282 | 0.028 |
Echinococcus granulosus | calpain | 0.0019 | 0.0029 | 0.0027 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.2678 | 0.6222 | 1 |
Onchocerca volvulus | 0.0037 | 0.0071 | 0.0393 | |
Schistosoma mansoni | loxhd1 | 0.0037 | 0.0071 | 0.0069 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.2678 | 0.6222 | 1 |
Echinococcus granulosus | dihydrofolate reductase | 0.43 | 1 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0068 | 0.0007 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0066 | 0.014 | 0.0138 |
Schistosoma mansoni | hypothetical protein | 0.0402 | 0.092 | 0.0919 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.2678 | 0.6222 | 1 |
Onchocerca volvulus | 0.0247 | 0.0562 | 0.3184 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.0282 | 0.028 |
Echinococcus multilocularis | calpain A | 0.0066 | 0.014 | 0.0138 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0008 | 0.0007 |
Chlamydia trachomatis | dihydrofolate reductase | 0.43 | 1 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0218 | 0.0492 | 0.049 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0037 | 0.0071 | 0.0069 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0142 | 0.0315 | 0.0314 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.0315 | 0.0314 |
Echinococcus multilocularis | hypothetical protein | 0.0019 | 0.0029 | 0.0027 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.022 | 0.0497 | 0.0495 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.0315 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0068 | 0.0066 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Activity at P2Y1 expressed in HEK293 cells at 10 uM to 1 nM | ChEMBL. | 18524586 | |
Activity (functional) | Antagonist activity at P2X7R in BzATP-stimulated rat spinal cord assessed as decrease in fluorescent propidium iodide dye uptake at 1 uM | ChEMBL. | 18524586 | |
Activity (binding) | Activity at P2Y2 receptor expressed in HEK293 cells at 10 uM to 1 nM | ChEMBL. | 18524586 | |
Activity (functional) | Agonist activity at P2Y4 receptor expressed in HEK293 cells at 10 uM to 1 nM | ChEMBL. | 18524586 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.