Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.3499 | 0.3499 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0023 | 0.0212 | 0.0607 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0023 | 0.0212 | 1 |
Trypanosoma brucei | unspecified product | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0023 | 0.0212 | 0.0212 |
Echinococcus granulosus | neuroligin | 0.0023 | 0.0212 | 0.0212 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.2197 | 0.2197 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0118 | 0.8471 | 0.8471 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.2197 | 0.2197 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0212 | 0.0212 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0118 | 0.8471 | 0.8471 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0212 | 0.0212 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2197 | 0.2197 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0023 | 0.0212 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.3499 | 0.3499 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0212 | 0.0212 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2197 | 0.2197 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0023 | 0.0212 | 0.0212 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.2197 | 0.2197 |
Onchocerca volvulus | 0.0023 | 0.0212 | 0.5 | |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.3499 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0023 | 0.0212 | 0.0212 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0212 | 0.0212 |
Onchocerca volvulus | 0.0023 | 0.0212 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.0136 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2197 | 0.2197 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0136 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.2197 | 0.2197 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0212 | 0.0212 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0023 | 0.0212 | 0.0607 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0212 | 0.0212 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | lipoxygenase | 0.0083 | 0.5387 | 0.5387 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0212 | 0.0212 |
Schistosoma mansoni | lipoxygenase | 0.0118 | 0.8471 | 0.8471 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.3499 | 0.3499 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0212 | 0.0212 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0136 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0212 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0212 | 0.0212 |
Onchocerca volvulus | 0.0023 | 0.0212 | 0.5 | |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0023 | 0.0212 | 0.0212 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0023 | 0.0212 | 0.0212 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0136 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0136 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0212 | 0.0212 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0212 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0212 | 0.0212 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0212 | 0.0212 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.3499 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.2197 | 0.2197 |
Echinococcus granulosus | carboxylesterase 5A | 0.0136 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0023 | 0.0212 | 0.0212 |
Brugia malayi | Cytochrome P450 family protein | 0.003 | 0.0803 | 0.0803 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.3499 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0212 | 0.0212 |
Onchocerca volvulus | 0.0023 | 0.0212 | 0.5 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.3499 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.3499 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0212 | 0.0212 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0023 | 0.0212 | 0.0212 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.3499 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0023 | 0.0212 | 0.0607 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0023 | 0.0212 | 0.0212 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0212 | 0.0212 |
Schistosoma mansoni | gliotactin | 0.0023 | 0.0212 | 0.0212 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0023 | 0.0212 | 0.0607 |
Onchocerca volvulus | 0.0023 | 0.0212 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0136 | 1 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.2197 | 0.2197 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0136 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0136 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0136 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0023 | 0.0212 | 0.0212 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0023 | 0.0212 | 0.0212 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.003 | 0.0803 | 0.0803 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.3499 | 0.3499 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.