Detailed information for compound 977297

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 425.36 | Formula: C22H14F3N3O3
  • H donors: 1 H acceptors: 3 LogP: 2.93 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1c(c2ccccc2)[n+]([O-])c2c([n+]1[O-])cc(cc2)C(F)(F)F)Nc1ccccc1
  • InChi: 1S/C22H14F3N3O3/c23-22(24,25)15-11-12-17-18(13-15)28(31)20(21(29)26-16-9-5-2-6-10-16)19(27(17)30)14-7-3-1-4-8-14/h1-13H,(H,26,29)
  • InChiKey: QKTFHLXJYIRZAS-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0258 0.158 0.158
Brugia malayi nuclear receptor RXR 0.0123 0.0697 0.0697
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0081 0.0081
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0235 0.1425 0.1859
Toxoplasma gondii hypothetical protein 0.0044 0.0184 0.024
Echinococcus granulosus growth factor receptor bound protein 2 0.0016 0.0002 0.0003
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0149 0.0183
Schistosoma mansoni opsin-like receptor 0.0081 0.0427 0.0557
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0028 0.0079 0.0079
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0047 0.0206 0.0168
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0081 0.0427 0.0557
Schistosoma mansoni hypothetical protein 0.0325 0.2012 0.2623
Schistosoma mansoni loxhd1 0.0021 0.0036 0.0047
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0044 0.0184 0.0184
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.011 0.0612 0.0798
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0235 0.1425 0.1425
Trypanosoma brucei proteasome beta 6 subunit 0.0928 0.5935 0.5935
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0028 0.0028
Echinococcus multilocularis neuropeptide receptor A26 0.0573 0.3626 0.4728
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0081 0.0427 0.0557
Trypanosoma brucei C-14 sterol reductase, putative 0.0051 0.0228 0.0228
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0235 0.1425 0.1859
Brugia malayi hypothetical protein 0.0081 0.0427 0.0427
Giardia lamblia Proteasome subunit beta type 3 0.0235 0.1425 0.1859
Brugia malayi Polyprenyl synthetase family protein 0.0028 0.0079 0.0079
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0232 0.141 0.141
Loa Loa (eye worm) hypothetical protein 0.0066 0.0329 0.0329
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0032 0.0042
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0111 0.0144
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0045 0.0059
Schistosoma mansoni hypothetical protein 0.0033 0.0117 0.0152
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) neuropeptide F receptor 0.0081 0.0427 0.0427
Echinococcus granulosus g protein coupled receptor 0.0081 0.0427 0.0557
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1694 0.2209
Schistosoma mansoni rab6-interacting 0.0021 0.0036 0.0047
Schistosoma mansoni tyrosine kinase 0.0173 0.1027 0.134
Plasmodium falciparum proteasome subunit beta type-5 0.1194 0.7668 1
Brugia malayi hypothetical protein 0.0018 0.0013 0.0013
Brugia malayi Nuclear hormone receptor-like 1 0.0123 0.0697 0.0697
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0047 0.0206 0.0257
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0047 0.0206 0.0206
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0032 0.0032
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0123 0.0697 0.0697
Leishmania major sterol C-24 reductase, putative 0.0051 0.0228 0.0228
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0235 0.1425 0.1859
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0032 0.0042
Echinococcus multilocularis proteasome subunit beta type 7 0.0235 0.1425 0.1859
Schistosoma mansoni hypothetical protein 0.0181 0.1077 0.1404
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0009 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0047 0.0206 0.0257
Echinococcus granulosus neuropeptide Y receptor 0.0081 0.0427 0.0557
Onchocerca volvulus 0.0021 0.0036 0.0008
Trypanosoma brucei cardiolipin synthetase, putative 0.0038 0.0148 0.0148
Echinococcus multilocularis allatostatin A receptor 0.0081 0.0427 0.0557
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0117 0.0152
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0235 0.1425 0.1425
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0081 0.0427 0.0557
Echinococcus multilocularis serotonin receptor 0.0211 0.1274 0.1662
Schistosoma mansoni hypothetical protein 0.0072 0.0369 0.0482
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0081 0.0427 0.0557
Brugia malayi G-protein coupled receptor 0.0081 0.0427 0.0427
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0047 0.0206 0.0168
Mycobacterium leprae Conserved hypothetical protein 0.0047 0.0206 0.0168
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0184 0.024
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0325 0.2012 0.2012
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0044 0.0184 0.024
Onchocerca volvulus Protein ultraspiracle homolog 0.0232 0.141 0.5084
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0032 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0427 0.0557
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0003 0.0004
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0032 0.0042
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0028 0.0079 0.0091
Echinococcus granulosus subfamily T1A non peptidase ue 0.0235 0.1425 0.1859
Brugia malayi Phospholipase d protein 1 0.011 0.0614 0.0614
Echinococcus multilocularis phospholipase D1 0.011 0.0614 0.08
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0427 0.0557
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0427 0.0557
Trypanosoma cruzi cytochrome P450, putative 0.0074 0.038 0.038
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0134 0.0774 0.1009
Echinococcus multilocularis dnaJ subfamily B 0.0437 0.2742 0.3576
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0232 0.141 0.1839
Schistosoma mansoni neuropeptide F-like receptor 0.0081 0.0427 0.0557
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0009 0.0009
Echinococcus multilocularis lamin b receptor 0.0051 0.0228 0.0297
Echinococcus multilocularis neuropeptide Y receptor 0.0081 0.0427 0.0557
Schistosoma mansoni smdr2 0.0023 0.0045 0.0059
Trypanosoma cruzi sterol C-24 reductase, putative 0.0051 0.0228 0.0228
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0047 0.0206 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0085 0.0111
Trypanosoma cruzi polyprenyl synthase, putative 0.0028 0.0079 0.0079
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0028 0.0079 0.0061
Loa Loa (eye worm) hypothetical protein 0.0072 0.0364 0.0364
Brugia malayi beta-lactamase family protein 0.0038 0.0149 0.0149
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0235 0.1425 0.1825
Brugia malayi hypothetical protein 0.002 0.0032 0.0032
Schistosoma mansoni coup transcription factor 0.0232 0.141 0.1839
Plasmodium falciparum importin beta, putative 0.003 0.0097 0.0126
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0047 0.0206 0.0206
Echinococcus multilocularis 0.0047 0.0206 0.0268
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0235 0.1425 0.1859
Echinococcus granulosus expressed protein 0.0399 0.2494 0.3252
Loa Loa (eye worm) hypothetical protein 0.0033 0.0111 0.0111
Mycobacterium leprae proteasome (beta subunit) PrcB 0.1194 0.7668 1
Schistosoma mansoni axis inhibition protein axin 0.002 0.0032 0.0042
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0047 0.0206 0.0257
Giardia lamblia 20S proteasome alpha subunit 2 0.0235 0.1425 0.1859
Echinococcus multilocularis neuropeptides capa receptor 0.0081 0.0427 0.0557
Entamoeba histolytica phospholipase D, putative 0.011 0.0614 0.0762
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0232 0.141 0.5084
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0235 0.1425 0.1859
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Schistosoma mansoni tyrosine kinase 0.0169 0.1001 0.1306
Onchocerca volvulus 0.0081 0.0427 0.1454
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0211 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0211 0.0275
Onchocerca volvulus 0.0081 0.0427 0.1454
Brugia malayi Nuclear hormone receptor E75 0.011 0.0612 0.0612
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0081 0.0427 0.0557
Brugia malayi nuclear receptor NHR-88 0.0232 0.141 0.141
Onchocerca volvulus Chorion peroxidase homolog 0.0028 0.0081 0.0177
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0184 0.0184
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0184 0.024
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0117 0.0117
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0045 0.0059
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0147 0.0147
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0235 0.1425 0.1859
Toxoplasma gondii heat shock protein hslv, putative 0.0235 0.1425 0.1859
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0047 0.0206 0.0168
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0235 0.1425 0.1425
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0003 0.0003
Brugia malayi nuclear hormone receptor family member nhr-6 0.011 0.0612 0.0612
Toxoplasma gondii proteasome subunit alpha1, putative 0.0235 0.1425 0.1859
Brugia malayi hypothetical protein 0.0081 0.0427 0.0427
Echinococcus multilocularis g-protein coupled receptor 0.0081 0.0427 0.0557
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0235 0.1425 0.1425
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0235 0.1425 0.1425
Schistosoma mansoni nuclear hormone receptor 0.0232 0.141 0.1839
Echinococcus granulosus somatostatin receptor 0.0081 0.0427 0.0557
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0045 0.0059
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0131 0.0171
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0149 0.0194
Loa Loa (eye worm) proteasome subunit beta type 3 0.0235 0.1425 0.1425
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.018 0.0235
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0081 0.0427 0.0427
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0081 0.0081
Onchocerca volvulus 0.0044 0.0184 0.0556
Schistosoma mansoni nuclear receptor 0.011 0.0612 0.0798
Leishmania major p-glycoprotein 0.0023 0.0045 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Echinococcus granulosus NCK adaptor protein 0.0016 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0142 0.0185
Echinococcus granulosus alpha 1A adrenergic receptor 0.0081 0.0427 0.0557
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0235 0.1425 0.1425
Echinococcus multilocularis cpg binding protein 0.0032 0.011 0.0143
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1694 0.2209
Brugia malayi hypothetical protein 0.0081 0.0427 0.0427
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0184 0.024
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0276 0.1694 0.1694
Brugia malayi Proteasome A-type and B-type family protein 0.1194 0.7668 0.7668
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0149 0.0183
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0235 0.1425 0.1859
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0042
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0235 0.1425 0.1859
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0142 0.0185
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0184 0.024
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.114 0.1487
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.0793 0.5062 0.5062
Echinococcus multilocularis neuropeptide s receptor 0.0573 0.3626 0.4728
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0149 0.0183
Leishmania major solanesyl-diphosphate synthase, putative 0.0028 0.0079 0.0079
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0149 0.0194
Leishmania major importin beta-1 subunit, putative 0.0025 0.0059 0.0059
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0045 0.0059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0232 0.141 0.1839
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0039 0.0154 0.02
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0034
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0235 0.1425 0.1859
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0427 0.0557
Schistosoma mansoni amine GPCR 0.0081 0.0427 0.0557
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.0587 0.0587
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0044 0.0044
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0928 0.5935 0.774
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0142 0.0142
Brugia malayi SRC-1 0.0051 0.0231 0.0231
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0575 0.3639 0.4745
Schistosoma mansoni phospholipase D 0.011 0.0614 0.08
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0235 0.1425 0.1859
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0081 0.0427 0.0427
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0018 0.0013 0.0017
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0149 0.0183
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0235 0.1425 0.1859
Loa Loa (eye worm) cytochrome P450 family protein 0.0088 0.0471 0.0471
Mycobacterium tuberculosis Conserved protein 0.0038 0.0149 0.0183
Schistosoma mansoni retinoic acid receptor RXR 0.0338 0.2096 0.2733
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0047 0.0206 0.0168
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0235 0.1425 1
Plasmodium falciparum transporter, putative 0.0044 0.0184 0.024
Schistosoma mansoni peroxidasin 0.0028 0.0081 0.0106
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0047 0.0206 0.0257
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0211 0.0211
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0036 0.0036
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0928 0.5935 0.5935
Schistosoma mansoni tyrosine kinase 0.002 0.0028 0.0037
Echinococcus multilocularis FTZ F1 alpha 0.0232 0.141 0.1839
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0123 0.0697 0.0909
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0338 0.2096 0.2733
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0149 0.0194
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0235 0.1425 0.1425
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0235 0.1425 0.1859
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0047 0.0206 0.0168
Brugia malayi AKH receptor 0.0081 0.0427 0.0427
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1194 0.7668 0.7668
Schistosoma mansoni amine GPCR 0.0081 0.0427 0.0557
Loa Loa (eye worm) TK/INSR protein kinase 0.0104 0.0576 0.0576
Echinococcus multilocularis thyroid hormone receptor alpha 0.0367 0.2286 0.2981
Echinococcus granulosus neuropeptide receptor 0.0081 0.0427 0.0557
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0235 0.1425 0.1859
Brugia malayi Tachykinin-like peptides receptor 99D 0.0081 0.0427 0.0427
Brugia malayi hypothetical protein 0.011 0.0612 0.0612
Echinococcus granulosus phospholipase D1 0.011 0.0614 0.08
Loa Loa (eye worm) cytochrome P450 0.0047 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Brugia malayi proteasome subunit alpha type 4 0.0235 0.1425 0.1425
Brugia malayi putative neuropeptide receptor NPR1 0.0081 0.0427 0.0427
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0131 0.0171
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0036 0.0047
Loa Loa (eye worm) hypothetical protein 0.0232 0.141 0.141
Schistosoma mansoni biogenic amine (5HT) receptor 0.0081 0.0427 0.0557
Mycobacterium leprae putative cytochrome p450 0.0047 0.0206 0.0168
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0045 0.0017
Schistosoma mansoni lipoxygenase 0.0088 0.0472 0.0615
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0235 0.1425 0.1825
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0032 0.0042
Schistosoma mansoni tyrosine kinase 0.0051 0.0231 0.0302
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0045 0.0059
Entamoeba histolytica protein kinase, putative 0.0035 0.0128 0.0126
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1694 0.2209
Loa Loa (eye worm) hypothetical protein 0.0087 0.0466 0.0466
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0135 0.0777 0.1013
Echinococcus granulosus peroxidasin 0.0028 0.0081 0.0106
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0081 0.0427 0.0427
Schistosoma mansoni myosin xvIII 0.0081 0.0427 0.0557
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0235 0.1425 0.1859
Echinococcus granulosus tm gpcr rhodopsin 0.0081 0.0427 0.0557
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0036 0.0047
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.009 0.0482 0.0629
Brugia malayi hypothetical protein 0.0021 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0092 0.0499 0.0499
Schistosoma mansoni neuropeptide F-like receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0081 0.0427 0.0427
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0081 0.0427 0.0557
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0036 0.0047
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0231 0.0302
Onchocerca volvulus 0.0081 0.0427 0.1454
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0232 0.141 0.1839
Toxoplasma gondii proteasome subunit beta type, putative 0.1194 0.7668 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0081 0.0427 0.0557
Schistosoma mansoni nuclear hormone receptor 0.011 0.0612 0.0798
Loa Loa (eye worm) hypothetical protein 0.0232 0.141 0.141
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0044
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0126 0.0719 0.0937
Loa Loa (eye worm) TK/EGFR protein kinase 0.0321 0.1987 0.1987
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0149 0.0194
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0032 0.0032
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0235 0.1425 0.1425
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0023 0.0045 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0018 0.0013 0.0017
Plasmodium vivax SET domain protein, putative 0.0033 0.0111 0.0144
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0016 0.0002 0.0002
Echinococcus multilocularis growth factor receptor bound protein 2 0.0016 0.0002 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0149 0.0149
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0235 0.1425 0.1859
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0184 0.024
Onchocerca volvulus Neuropeptide F receptor homolog 0.0081 0.0427 0.1454
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0235 0.1425 0.1425
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0149 0.0194
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1694 0.2209
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.011 0.0612 0.0612
Trichomonas vaginalis esterase, putative 0.0038 0.0149 0.0194
Mycobacterium leprae Probable lipase LipE 0.0038 0.0149 0.0093
Echinococcus granulosus proteasome subunit alpha type 2 0.0235 0.1425 0.1859
Echinococcus granulosus Nuclear hormone receptor HR96 0.011 0.0612 0.0798
Echinococcus granulosus neuropeptide receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Brugia malayi larval opioid receptor 0.0081 0.0427 0.0427
Schistosoma mansoni cpg binding protein 0.0031 0.0098 0.0128
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0045 0.0059
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0184 0.024
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0437 0.2742 0.2742
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0081 0.0081
Echinococcus multilocularis Nuclear hormone receptor HR96 0.011 0.0612 0.0798
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0081 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0033 0.0117 0.0117
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0184 0.024
Onchocerca volvulus Bile acid receptor homolog 0.0232 0.141 0.5084
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0047 0.0206 0.0168
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0097 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0067 0.0088
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0045 0.0017
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0235 0.1425 0.1859
Trypanosoma brucei cytochrome P450, putative 0.0074 0.038 0.038
Mycobacterium tuberculosis Conserved protein 0.0038 0.0149 0.0183
Plasmodium vivax proteasome subunit beta type-7, putative 0.0235 0.1425 0.1859
Brugia malayi proteasome subunit alpha type 6 0.0235 0.1425 0.1425
Entamoeba histolytica phospholipase D, putative 0.011 0.0614 0.0762
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0149 0.0194
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0081 0.0427 0.0557
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0047 0.0206 0.0168
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1077 0.1404
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0028 0.0079 0.0079
Mycobacterium ulcerans proteasome PrcA 0.0235 0.1425 0.1774
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0009 0.0011
Trypanosoma cruzi C-14 sterol reductase, putative 0.0051 0.0228 0.0228
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0047 0.0206 0.0257
Entamoeba histolytica hypothetical protein 0.0038 0.0149 0.0153
Brugia malayi Proteasome A-type and B-type family protein 0.0235 0.1425 0.1425
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0003 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0009 0.0011
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0047 0.0206 0.0206
Schistosoma mansoni amine GPCR 0.0081 0.0427 0.0557
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0081 0.0427 0.0557
Leishmania major proteasome beta 3 subunit, putative 0.0235 0.1425 0.1425
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0028 0.0079 0.0102
Brugia malayi Pre-SET motif family protein 0.0223 0.135 0.135
Echinococcus multilocularis RUN 0.0021 0.0036 0.0047
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0211 0.0235
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0437 0.2742 0.2742
Echinococcus multilocularis GA binding protein alpha chain 0.0077 0.0402 0.0524
Brugia malayi hypothetical protein 0.0081 0.0427 0.0427
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0142 0.0185
Toxoplasma gondii proteasome beta subunit 0.0235 0.1425 0.1859
Brugia malayi Ets-domain containing protein 0.0077 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0044 0.0184 0.0184
Echinococcus multilocularis 0.0099 0.0541 0.0705
Echinococcus granulosus microtubule associated protein 2 0.0737 0.4696 0.6124
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0028 0.0079 0.0102
Loa Loa (eye worm) polyprenyl synthetase 0.0028 0.0079 0.0079
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0003 0.0003
Leishmania major polyprenyl synthase, putative 0.0028 0.0079 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0036
Echinococcus granulosus lamin b receptor 0.0051 0.0228 0.0297
Echinococcus granulosus multidrug resistance protein 1 0.0016 0.0001 0.0001
Echinococcus multilocularis phospholipase D 0.0097 0.053 0.0692
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0111 0.0144
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0081 0.0427 0.0557
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0235 0.1425 0.1425
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0081 0.0081
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0184 0.024
Mycobacterium ulcerans lipase LipD 0.0038 0.0149 0.0093
Trichomonas vaginalis set domain proteins, putative 0.0254 0.155 0.2021
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0045 0.0059
Echinococcus multilocularis jun protein 0.009 0.0482 0.0629
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0051 0.0231 0.0302
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0235 0.1425 0.1425
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0135 0.0777 0.0777
Toxoplasma gondii cytochrome p450 superfamily protein 0.0047 0.0206 0.0268
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0149 0.0149
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0427 0.0557
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0059 0.0077
Loa Loa (eye worm) hypothetical protein 0.0232 0.141 0.141
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0051 0.0231 0.0302
Onchocerca volvulus 0.0081 0.0427 0.1454
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.0155 0.0202
Loa Loa (eye worm) hypothetical protein 0.0072 0.0364 0.0364
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0147 0.0192
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0044 0.0044
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0042
Loa Loa (eye worm) G-protein coupled receptor 0.0081 0.0427 0.0427
Echinococcus granulosus tm gpcr rhodopsin 0.0634 0.4025 0.525
Echinococcus granulosus proteasome subunit beta type 7 0.0235 0.1425 0.1859
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0028 0.0079 0.0061
Schistosoma mansoni axis inhibition protein axin 0.002 0.0032 0.0042
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0235 0.1425 0.1825
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0235 0.1425 0.1859
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0081 0.0427 0.0557
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0235 0.1425 0.1825
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0235 0.1425 0.1425
Brugia malayi nuclear receptor NHR-88 0.011 0.0612 0.0612
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0044 0.0058
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0059 0.0059
Loa Loa (eye worm) polyprenyl synthetase 0.011 0.0612 0.0612
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0044 0.0184 1
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.011 0.0612 0.0798
Brugia malayi G-protein coupled receptor 0.0081 0.0427 0.0427
Onchocerca volvulus Notchless protein homolog 0.0235 0.1425 0.5139
Schistosoma mansoni amine GPCR 0.0081 0.0427 0.0557
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0081 0.0427 0.0427
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0235 0.1425 0.1859
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0232 0.141 0.141
Leishmania major proteasome beta 5 subunit, putative 0.1194 0.7668 0.7668
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0235 0.1425 0.1425
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0123 0.0697 0.0909
Brugia malayi Importin beta-1 subunit 0.003 0.0097 0.0097
Brugia malayi Dopamine receptor protein 2 0.0081 0.0427 0.0427
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0235 0.1425 0.1425
Loa Loa (eye worm) proteasome subunit beta type 2 0.0575 0.3639 0.3639
Schistosoma mansoni hypothetical protein 0.0033 0.0117 0.0152
Schistosoma mansoni opsin-like receptor 0.0081 0.0427 0.0557
Brugia malayi hypothetical protein 0.0081 0.0427 0.0427
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0045 0.0059
Entamoeba histolytica hypothetical protein 0.0025 0.0059 0.0036
Brugia malayi PXA domain containing protein 0.0025 0.0063 0.0063
Brugia malayi hypothetical protein 0.011 0.0612 0.0612
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0147 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0067 0.0088
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0276 0.1694 0.1694
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0395 0.2472 0.3223
Entamoeba histolytica P-glycoprotein-1 0.0023 0.0045 0.0017
Brugia malayi putative neuropeptide receptor 0.0081 0.0427 0.0427
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0634 0.4025 0.525
Echinococcus granulosus thyroid hormone receptor alpha 0.011 0.0612 0.0798
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Echinococcus multilocularis phospholipase d3 0.0021 0.0034 0.0044
Echinococcus granulosus serotonin receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.114 0.1487
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0235 0.1425 0.1859
Brugia malayi Ets-domain containing protein 0.0077 0.0402 0.0402
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0081 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0044 0.0184 0.0184
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0036 0.0047
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0045 0.0059
Echinococcus multilocularis neuropeptides capa receptor 0.0081 0.0427 0.0557
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0084 0.0109
Loa Loa (eye worm) neuropeptide F receptor 0.0081 0.0427 0.0427
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0235 0.1425 0.1425
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0043 0.018 0.0235
Brugia malayi hypothetical protein 0.0028 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Plasmodium falciparum basic transcription factor 3b, putative 0.0037 0.0142 0.0185
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.011 0.0612 0.0798
Echinococcus multilocularis GPCR, family 2 0.0033 0.0117 0.0152
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0235 0.1425 0.1825
Schistosoma mansoni neuropeptide receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.0123 0.0697 0.0697
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0097 0.0126
Schistosoma mansoni neuropeptide receptor 0.0081 0.0427 0.0557
Onchocerca volvulus 0.0028 0.0081 0.0177
Echinococcus granulosus tyrosine protein kinase Src42A 0.0039 0.0154 0.02
Echinococcus granulosus neuropeptide FF receptor 2 0.0081 0.0427 0.0557
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1552 1 1
Plasmodium vivax amine transporter, putative 0.0044 0.0184 0.024
Echinococcus multilocularis snurportin 1 0.0325 0.2012 0.2623
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.011 0.0612 0.0798
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0928 0.5935 0.774
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0117 0.0117
Giardia lamblia 20S proteasome alpha subunit 3 0.0235 0.1425 0.1859
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus granulosus sex peptide receptor 0.0081 0.0427 0.0557
Echinococcus granulosus transcription factor btf3 0.0037 0.0142 0.0185
Loa Loa (eye worm) hypothetical protein 0.0123 0.0697 0.0697
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0184 0.024
Brugia malayi hypothetical protein 0.0123 0.0697 0.0697
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0235 0.1425 0.1859
Loa Loa (eye worm) hypothetical protein 0.0044 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Loa Loa (eye worm) hypothetical protein 0.0072 0.0369 0.0369
Schistosoma mansoni multidrug resistance protein 0.0023 0.0045 0.0059
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0123 0.0697 0.0909
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0184 0.024
Brugia malayi hypothetical protein 0.002 0.0032 0.0032
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0235 0.1425 0.1859
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0235 0.1425 0.1825
Echinococcus granulosus fmrfamide receptor 0.0081 0.0427 0.0557
Entamoeba histolytica transcription factor BTF3, putative 0.0037 0.0142 0.0144
Echinococcus multilocularis sex peptide receptor 0.0081 0.0427 0.0557
Plasmodium vivax multidrug resistance protein 1, putative 0.0023 0.0045 0.0059
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0045 0.0059
Onchocerca volvulus 0.0081 0.0427 0.1454
Loa Loa (eye worm) melatonin receptor type 1A 0.0081 0.0427 0.0427
Schistosoma mansoni biogenic amine receptor 0.0081 0.0427 0.0557
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0123 0.0697 0.0909
Schistosoma mansoni lipoxygenase 0.0126 0.0719 0.0937
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0042
Schistosoma mansoni neuropeptide receptor 0.0081 0.0427 0.0557
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0059 0.0077
Schistosoma mansoni peroxidasin 0.0028 0.0081 0.0106
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Brugia malayi neuropeptide F receptor 0.0081 0.0427 0.0427
Echinococcus granulosus GPCR family 2 0.0033 0.0117 0.0152
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1077 0.1404
Mycobacterium ulcerans beta-lactamase 0.0038 0.0149 0.0093
Brugia malayi bZIP transcription factor family protein 0.009 0.0482 0.0482
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0235 0.1425 0.1425
Plasmodium vivax importin-beta 2, putative 0.003 0.0097 0.0126
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0081 0.0427 0.0557
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1077 0.1404
Entamoeba histolytica Ran family GTPase 0.0022 0.0044 0.0016
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0044 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0232 0.141 0.141
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.011 0.0612 0.0798
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0051 0.0231 0.0302
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.011 0.0612 0.0798
Toxoplasma gondii proteasome subunit 0.0235 0.1425 0.1859
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0149 0.0093
Loa Loa (eye worm) fli-1 protein 0.0235 0.1427 0.1427
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0235 0.1425 0.1859
Onchocerca volvulus Glucosylceramidase homolog 0.0181 0.1077 0.3852
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0003 0.0003
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0135 0.0777 0.0777
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0235 0.1425 0.1859
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.011 0.0612 0.0798
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0021 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0232 0.141 0.141
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0232 0.141 0.141
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0928 0.5935 0.5935
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus multilocularis neuropeptide Y receptor 0.0081 0.0427 0.0557
Brugia malayi Phospholipase D. Active site motif family protein 0.0038 0.0148 0.0148
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0045 0.0059
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0051 0.0231 0.0302
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0395 0.2472 0.3223
Schistosoma mansoni rab6-interacting 0.0021 0.0036 0.0047
Brugia malayi Protein K4 0.0018 0.0013 0.0013
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0044 0.0057
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0235 0.1425 0.1859
Trypanosoma cruzi cardiolipin synthetase, putative 0.0038 0.0148 0.0148
Brugia malayi Nuclear hormone receptor E75 0.011 0.0612 0.0612
Loa Loa (eye worm) TK protein kinase 0.0043 0.018 0.018
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0028 0.0079 0.0061
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0235 0.1425 0.1425
Onchocerca volvulus Peroxidase homolog 0.0028 0.0081 0.0177
Schistosoma mansoni steroid hormone receptor ad4bp 0.0232 0.141 0.1839
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0232 0.141 0.1839
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0003 0.0004
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0142 0.0142
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.011 0.0612 0.0612
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0232 0.141 0.1839
Trypanosoma brucei farnesyl pyrophosphate synthase 0.011 0.0612 0.0612
Loa Loa (eye worm) nuclear receptor nhr-7B 0.011 0.0612 0.0612
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0235 0.1425 0.1859
Brugia malayi Cytochrome P450 family protein 0.0074 0.038 0.038
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0235 0.1425 0.1774
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Leishmania major proteasome beta 2 subunit, putative 0.0575 0.3639 0.3639
Echinococcus granulosus tyrosine protein kinase Src64B 0.0051 0.0231 0.0302
Brugia malayi beta-NAC-like protein 0.0037 0.0142 0.0142
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0184 0.024
Echinococcus granulosus neuropeptide receptor A26 0.0573 0.3626 0.4728
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0047 0.0206 0.0168
Loa Loa (eye worm) TK protein kinase 0.0035 0.0128 0.0128
Schistosoma mansoni hypothetical protein 0.0081 0.0427 0.0557
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0023 0.0045 0.0059
Brugia malayi hypothetical protein 0.0081 0.0427 0.0427
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0036 0.0047
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0047 0.0206 0.0257
Echinococcus multilocularis insulin receptor 0.0104 0.0576 0.0751
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0211 0.0275
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.0155 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0108 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0042
Onchocerca volvulus 0.0081 0.0427 0.1454
Toxoplasma gondii proteasome subunit alpha type, putative 0.0235 0.1425 0.1859
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0149 0.0183
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0009 0.0011
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.011 0.0612 0.2135
Schistosoma mansoni hypothetical protein 0.0181 0.1077 0.1404
Onchocerca volvulus 0.0081 0.0427 0.1454
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0235 0.1425 0.1859
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.011 0.0612 0.0798
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0235 0.1425 0.1859
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0009 0.0011
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0081 0.0427 0.0557
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0235 0.1425 0.1859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0084 0.0109
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0235 0.1425 0.1859
Onchocerca volvulus Peroxidasin homolog 0.0028 0.0081 0.0177
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0047 0.0206 0.0257
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0023 0.0045 0.0045
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0047 0.0206 0.0257
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0045 0.0059
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0032 0.0042
Echinococcus granulosus neuropeptide s receptor 0.0573 0.3626 0.4728
Brugia malayi steroid hormone receptor 0.0232 0.141 0.141
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1077 0.1404
Brugia malayi Proteasome subunit alpha type 1 0.0235 0.1425 0.1425
Brugia malayi photoreceptor-specific nuclear receptor 0.0232 0.141 0.141
Loa Loa (eye worm) hypothetical protein 0.0106 0.0587 0.0587
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0232 0.141 0.141
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1694 0.2209
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0003 0.0003
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.1194 0.7668 1
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0032 0.0042
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0032 0.0042
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0235 0.1425 0.1425
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0232 0.141 0.141
Leishmania major proteasome beta 2 subunit, putative 0.0235 0.1425 0.1425
Brugia malayi hypothetical protein 0.013 0.0745 0.0745
Brugia malayi proteasome subunit beta type 1 0.0928 0.5935 0.5935
Echinococcus granulosus RUN 0.0021 0.0036 0.0047
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0028 0.0079 0.0463
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0575 0.3639 0.4745
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0235 0.1425 0.1425
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.011 0.0612 0.2135
Schistosoma mansoni cytochrome P450 0.0047 0.0206 0.0268
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0047 0.0206 0.0168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0211 0.0275
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0044 0.0184 0.024
Schistosoma mansoni glutathione synthetase 0.0028 0.0079 0.0102
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0032 0.0042
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.1498 0.1944
Schistosoma mansoni hypothetical protein 0.0038 0.0149 0.0194
Brugia malayi hypothetical protein 0.0021 0.0036 0.0036
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0235 0.1425 0.1825
Brugia malayi nuclear hormone receptor 0.0232 0.141 0.141
Echinococcus granulosus dro:myosuppressin receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.0339 0.2104 0.2104
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0235 0.1425 0.1859
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0232 0.141 0.1839
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0032 0.0042
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0045 0.0059
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0044 0.0184 0.024
Plasmodium falciparum proteasome subunit beta type-4 0.0235 0.1425 0.1859
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0032 0.0042
Echinococcus granulosus g protein coupled receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0232 0.141 0.141
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0928 0.5935 0.773
Brugia malayi proteasome subunit alpha type 1 0.0235 0.1425 0.1425
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0211 0.0275
Schistosoma mansoni cpg binding protein 0.0032 0.011 0.0143
Echinococcus granulosus jun protein 0.009 0.0482 0.0629
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0045 0.0059
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0117 0.0117
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0047 0.0206 0.0257
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1694 0.2209
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0235 0.1425 0.1425
Schistosoma mansoni tyrosine kinase 0.0321 0.1987 0.2591
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0131 0.0171
Schistosoma mansoni nuclear hormone receptor 0.011 0.0612 0.0798
Schistosoma mansoni growth factor receptor-bound protein 0.0016 0.0002 0.0003
Echinococcus multilocularis Nuclear hormone receptor HR96 0.011 0.0612 0.0798
Entamoeba histolytica hypothetical protein 0.0037 0.0142 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0042
Trypanosoma brucei proteasome alpha 7 subunit 0.0235 0.1425 0.1425
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0235 0.1425 0.1425
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0235 0.1425 0.1425
Onchocerca volvulus 0.0081 0.0427 0.1454
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0232 0.141 0.1839
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0235 0.1425 0.1859
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0081 0.0081
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0081 0.0427 0.0557
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0081 0.0427 0.0427
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.011 0.0612 0.0798
Trypanosoma cruzi polyprenyl synthase, putative 0.0028 0.0079 0.0079
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0575 0.3639 0.4745
Trichomonas vaginalis abcb9, putative 0.0023 0.0045 0.0059
Brugia malayi neuropeptide F receptor 0.0081 0.0427 0.0427
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0104 0.0576 0.0751
Leishmania major proteasome alpha 3 subunit, putative 0.0235 0.1425 0.1425
Mycobacterium ulcerans proteasome PrcB 0.1194 0.7668 1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0047 0.0206 0.0257
Schistosoma mansoni tyrosine kinase 0.0051 0.0231 0.0302
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0427 0.0557
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0018 0.0013 0.0017
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.011 0.0612 0.0702
Echinococcus granulosus orexin receptor type 2 0.0081 0.0427 0.0557
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0231 0.0302
Brugia malayi Dopamine receptor 0.0081 0.0427 0.0427
Echinococcus granulosus epidermal growth factor receptor 0.0173 0.1027 0.134
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0235 0.1425 0.1425
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0235 0.1425 0.1859
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0235 0.1425 0.1425
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0147 0.0192
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0149 0.0194
Onchocerca volvulus 0.0021 0.0036 0.0008
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0028 0.0079 0.0102
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0032 0.0042
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0045 0.0059
Onchocerca volvulus 0.0031 0.0098 0.0239
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0047 0.0206 0.0257
Brugia malayi RE15519p 0.0081 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0042
Echinococcus granulosus proteasome prosome macropain 0.1194 0.7668 1
Brugia malayi tailless protein 0.011 0.0612 0.0612
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0235 0.1425 0.1859
Giardia lamblia 20S proteasome alpha subunit 1 0.0235 0.1425 0.1859
Brugia malayi proteasome subunit alpha type 3 0.0235 0.1425 0.1425
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0149 0.0194
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0231 0.0302
Entamoeba histolytica P-glycoprotein-2, putative 0.0023 0.0045 0.0017
Loa Loa (eye worm) hypothetical protein 0.0232 0.141 0.141
Onchocerca volvulus 0.0254 0.155 0.5599
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Brugia malayi ecdysteroid receptor 0.0232 0.141 0.141
Echinococcus granulosus cytochrome P450 2K1 0.0047 0.0206 0.0268
Leishmania major basic transcription factor 3a, putative 0.0037 0.0142 0.0142
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0235 0.1425 0.1425
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0074 0.038 0.0397
Trypanosoma cruzi 20S proteasome subunit 0.0575 0.3639 0.3639
Schistosoma mansoni tyrosine kinase 0.0104 0.0576 0.0751
Loa Loa (eye worm) proteasome subunit beta type 1 0.0928 0.5935 0.5935
Trichomonas vaginalis abcb9, putative 0.0023 0.0045 0.0059
Echinococcus multilocularis ecdysone induced protein 78C 0.0232 0.141 0.1839
Trypanosoma cruzi Emopamil binding protein, putative 0.0437 0.2742 0.2742
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0032 0.0042
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0032 0.0032
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0235 0.1425 0.1859
Echinococcus granulosus phospholipase d3 0.0021 0.0034 0.0044
Echinococcus multilocularis epidermal growth factor receptor 0.0173 0.1027 0.134
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0042
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0044 0.0058
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0045 0.0059
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0081 0.0427 0.0557
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0045 0.0059
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0032 0.0032
Echinococcus multilocularis microtubule associated protein 2 0.0737 0.4696 0.6124
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0009 0.0011
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0235 0.1425 0.1825
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0077 0.0402 0.0402
Schistosoma mansoni ets-related 0.0235 0.1427 0.1861
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0138 0.018
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0047 0.0206 0.0168
Echinococcus multilocularis serotonin transporter 0.0258 0.158 0.206
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0042
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0235 0.1425 0.1425
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0235 0.1425 0.1859
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0117 0.0152
Schistosoma mansoni biogenic amine receptor 0.0081 0.0427 0.0557
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0117 0.0152
Echinococcus multilocularis serotonin receptor 0.0211 0.1274 0.1662
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0235 0.1425 0.1859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0085 0.0111
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0235 0.1425 0.1425
Giardia lamblia Farnesyl diphosphate synthase 0.011 0.0612 0.0798
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0028 0.0079 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0003 0.0004
Schistosoma mansoni ran 0.0022 0.0044 0.0058
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0575 0.3639 0.4723
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0045 0.0059
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0184 0.0184
Brugia malayi 20S proteasome alpha5 subunit 0.0235 0.1425 0.1425
Echinococcus granulosus allatostatin A receptor 0.0081 0.0427 0.0557
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0232 0.141 0.1839
Onchocerca volvulus Peroxidase homolog 0.0028 0.0081 0.0177
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0002
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0235 0.1425 0.1859
Echinococcus granulosus Proteasome subunit alpha beta 0.0235 0.1425 0.1859
Echinococcus granulosus phospholipase D 0.0097 0.053 0.0692
Mycobacterium ulcerans hypothetical protein 0.0038 0.0149 0.0093
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0045 0.0059
Plasmodium vivax cardiolipin synthetase, putative 0.0018 0.0013 0.0017
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0184 0.0184
Echinococcus granulosus tyrosine protein kinase Blk 0.0043 0.018 0.0235
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.0587 0.0587
Loa Loa (eye worm) hypothetical protein 0.0027 0.0073 0.0073
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) TYRA-2 protein 0.0081 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0524 0.3306 0.3306
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Echinococcus granulosus neuropeptides capa receptor 0.0081 0.0427 0.0557
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0047 0.0206 0.0206
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0928 0.5935 0.774
Brugia malayi Sex muscle abnormal protein 5 0.0016 0.0002 0.0002
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0045 0.0059
Brugia malayi hypothetical protein 0.0081 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0575 0.3639 0.4745
Brugia malayi Proteasome subunit alpha type 7-1 0.0235 0.1425 0.1425
Leishmania major hypothetical protein, conserved 0.0038 0.0149 0.0149
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0081 0.0427 0.0557
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0235 0.1425 0.1825
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0575 0.3639 0.4745
Schistosoma mansoni hypothetical protein 0.0081 0.0427 0.0557
Echinococcus multilocularis orexin receptor type 2 0.0081 0.0427 0.0557
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0045 0.0059
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0081 0.0081
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0235 0.1425 0.1859
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0003 0.0004
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0016 0.0002 0.0003
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.0155 0.0155
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0028 0.0079 0.0102
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.1194 0.7668 1
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0051 0.0231 0.0302
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Echinococcus granulosus geminin 0.0181 0.1077 0.1404
Loa Loa (eye worm) hypothetical protein 0.0038 0.0149 0.0149
Entamoeba histolytica P-glycoprotein-5 0.0023 0.0045 0.0017
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0003 0.0003
Trypanosoma brucei C-8 sterol isomerase, putative 0.1552 1 1
Schistosoma mansoni trans-prenyltransferase 0.0028 0.0079 0.0102
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0134 0.0774 0.1009
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0051 0.0231 0.0302
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0126 0.0719 0.0937
Echinococcus multilocularis geminin 0.0181 0.1077 0.1404
Schistosoma mansoni nuclear receptor nhr-48 0.011 0.0612 0.0798
Schistosoma mansoni hypothetical protein 0.0073 0.0373 0.0487
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0135 0.0777 0.0777
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0092 0.0499 0.0612
Brugia malayi Peroxidasin 0.0028 0.0081 0.0081
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0023 0.0045 0.0048
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0149 0.0194
Loa Loa (eye worm) hypothetical protein 0.0524 0.3306 0.3306
Brugia malayi G protein-coupled receptor 0.0081 0.0427 0.0427
Brugia malayi hypothetical protein 0.0038 0.0149 0.0149
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0009 0.0009
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0575 0.3639 0.3639
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0111 0.0144
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0235 0.1425 0.1825
Schistosoma mansoni thyroid hormone receptor 0.0367 0.2286 0.2981
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0235 0.1425 0.1425
Brugia malayi follicle stimulating hormone receptor 0.0081 0.0427 0.0427
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0211 0.0275
Leishmania major cytochrome p450-like protein 0.0074 0.038 0.038
Onchocerca volvulus 0.0028 0.0081 0.0177
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0232 0.141 0.141
Echinococcus multilocularis importin subunit beta 1 0.003 0.0097 0.0126
Brugia malayi hypothetical protein 0.0081 0.0427 0.0427
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0211 0.0211
Echinococcus granulosus farnesyl pyrophosphate synthase 0.011 0.0612 0.0798
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0235 0.1425 0.1859
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0047 0.0206 0.0168
Schistosoma mansoni histamine h1 receptor 0.0081 0.0427 0.0557
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0184 0.024
Loa Loa (eye worm) phospholipase D 0.0021 0.0034 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0165 0.0216
Trypanosoma cruzi cardiolipin synthetase, putative 0.0038 0.0148 0.0148
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Echinococcus multilocularis fmrfamide receptor 0.0081 0.0427 0.0557
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0235 0.1425 0.1825
Leishmania major proteasome alpha 1 subunit, putative 0.0235 0.1425 0.1425
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0028 0.0079 0.0091
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0231 0.0302
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0032 0.0032
Leishmania major GTP-binding protein, putative 0.0022 0.0044 0.0044
Echinococcus multilocularis nuclear receptor nhr 48 0.011 0.0612 0.0798
Plasmodium vivax proteasome subunit beta type-3, putative 0.0235 0.1425 0.1859
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0395 0.2472 0.3223
Giardia lamblia Proteasome subunit beta type 1 0.0928 0.5935 0.774
Brugia malayi multidrug resistance protein 3 0.0023 0.0045 0.0045
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0028 0.0079 0.0102
Loa Loa (eye worm) RGS-3 protein 0.002 0.0032 0.0032
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0099 0.0129
Schistosoma mansoni hypothetical protein 0.0081 0.0427 0.0557
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0184 0.024
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0235 0.1425 0.1425
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0045 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.0128 0.0167
Brugia malayi G protein-coupled receptor F59B2.13 0.0081 0.0427 0.0427
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0235 0.1425 0.1859
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0235 0.1425 0.1425
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0047 0.0206 0.0206
Onchocerca volvulus 0.0038 0.0149 0.0426
Onchocerca volvulus 0.0081 0.0427 0.1454
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0149 0.0194
Echinococcus granulosus proteasome subunit beta type 6 0.0235 0.1425 0.1859
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0235 0.1425 0.1859
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.1194 0.7668 0.7668
Echinococcus multilocularis proteasome subunit alpha type 6 0.0235 0.1425 0.1859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0003 0.0004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0211 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0101 0.0132
Echinococcus granulosus peptide allatostatin:somatostatin 0.0081 0.0427 0.0557
Entamoeba histolytica P-glycoprotein 5, putative 0.0023 0.0045 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0067 0.0088
Trypanosoma cruzi sterol C-24 reductase, putative 0.0051 0.0228 0.0228
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0003 0.0003
Echinococcus granulosus G protein coupled receptor 139 0.0081 0.0427 0.0557
Trichomonas vaginalis taga, putative 0.0023 0.0045 0.0059
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0232 0.141 0.1839
Giardia lamblia 20S proteasome alpha subunit 6 0.0235 0.1425 0.1859
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Schistosoma mansoni multidrug resistance protein 0.0023 0.0045 0.0059
Schistosoma mansoni multidrug resistance protein 0.0023 0.0045 0.0059
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0184 0.024
Onchocerca volvulus 0.0081 0.0427 0.1454
Echinococcus granulosus tyrosine kinase 0.0043 0.018 0.0235
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Brugia malayi ORL1-like opioid receptor 0.0081 0.0427 0.0427
Schistosoma mansoni hypothetical protein 0.0047 0.0206 0.0268
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0232 0.141 0.141
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0044 0.0184 0.024
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0028 0.0079 0.0102
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0492 0.3101 0.3101
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0427 0.0557
Schistosoma mansoni opsin-like receptor 0.0081 0.0427 0.0557
Leishmania major C-14 sterol reductase, putative 0.0051 0.0228 0.0228
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0223 0.135 0.135
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0149 0.0149
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0235 0.1425 0.1425
Loa Loa (eye worm) hypothetical protein 0.0211 0.1274 0.1274
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0232 0.141 0.141
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0047 0.0206 0.0168
Schistosoma mansoni microtubule-associated protein tau 0.0737 0.4696 0.6124
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0081 0.0427 0.0557
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0232 0.141 0.1839
Brugia malayi Tyrosine-protein kinase abl-1 0.002 0.0028 0.0028
Echinococcus granulosus Proteasome subunit alpha type 7 0.0235 0.1425 0.1859
Trypanosoma brucei transcription factor BTF3, putative 0.0037 0.0142 0.0142
Entamoeba histolytica P-glyco protein 6, putative 0.0023 0.0045 0.0017
Schistosoma mansoni nuclear receptor 0.011 0.0612 0.0798
Mycobacterium tuberculosis Conserved protein 0.0038 0.0149 0.0183
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0045 0.0059
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0032 0.0042
Echinococcus multilocularis somatostatin receptor 0.0081 0.0427 0.0557
Onchocerca volvulus 0.0038 0.0149 0.0426
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0018 0.0013 0.0013
Brugia malayi hypothetical protein 0.0081 0.0427 0.0427
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0427 0.0557
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0028 0.0079 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0032 0.0042
Brugia malayi Blistered cuticle protein 3 0.0028 0.0081 0.0081
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0032 0.0042
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0369 0.0369
Echinococcus granulosus g protein coupled receptor 0.0081 0.0427 0.0557
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0235 0.1425 0.1859
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0235 0.1425 0.1425
Onchocerca volvulus 0.0081 0.0427 0.1454
Echinococcus granulosus 7TM GPCR rhodopsin 0.0081 0.0427 0.0557
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.011 0.0612 0.0702
Schistosoma mansoni cpg binding protein 0.0032 0.011 0.0143
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0016 0.0002 0.0002
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0028 0.0079 0.3828
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0045 0.0059
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0003 0.0004
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0235 0.1425 0.1859
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0045 0.0059
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0235 0.1425 0.1859
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0036 0.0047
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0235 0.1425 0.1425
Echinococcus granulosus importin subunit beta 1 0.003 0.0097 0.0126
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0032 0.0042
Echinococcus granulosus neuropeptide Y receptor 0.0081 0.0427 0.0557
Echinococcus granulosus hypothetical protein 0.0818 0.5225 0.6814
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0047 0.0206 0.0168
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0047 0.0206 0.0168
Schistosoma mansoni biogenic amine receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Loa Loa (eye worm) multidrug resistance protein 3 0.0023 0.0045 0.0045
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0081 0.0427 0.0557
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0235 0.1425 0.1825
Brugia malayi Protein kinase domain containing protein 0.0104 0.0576 0.0576
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.0104 0.0576 0.0751
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0003 0.0003
Brugia malayi conserved hypotetical protein 0.011 0.0612 0.0612
Plasmodium vivax proteasome subunit beta type-4, putative 0.0235 0.1425 0.1859
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0111 0.0144
Echinococcus multilocularis G-protein coupled receptor, putative 0.0081 0.0427 0.0557
Echinococcus granulosus tachykinin peptides receptor 99D 0.0081 0.0427 0.0557
Schistosoma mansoni importin beta-1 0.003 0.0097 0.0126
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0135 0.0777 0.1013
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0045 0.0059
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0575 0.3639 0.3639
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0045 0.0059
Brugia malayi Cytochrome P450 family protein 0.0074 0.038 0.038
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0149 0.0194
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0045 0.0059
Brugia malayi RNA, U transporter 1 0.0086 0.0461 0.0461
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0232 0.141 0.1839
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0928 0.5935 0.5935
Schistosoma mansoni alpha-1 adrenergic receptor 0.0081 0.0427 0.0557
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0211 0.0211
Brugia malayi Fli-1 protein 0.0235 0.1427 0.1427
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0045 0.0059
Loa Loa (eye worm) hypothetical protein 0.0038 0.0149 0.0149
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0045 0.0059
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0022 0.0044 0.0057
Echinococcus granulosus neuropeptides capa receptor 0.0081 0.0427 0.0557
Schistosoma mansoni transcription factor btf3 0.0037 0.0142 0.0185
Schistosoma mansoni hypothetical protein 0.0021 0.0036 0.0047
Echinococcus multilocularis NCK adaptor protein 0.0016 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0232 0.141 0.141
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0235 0.1425 0.1425
Leishmania major proteasome beta 7 subunit, putative 0.0235 0.1425 0.1425
Echinococcus granulosus Nuclear hormone receptor HR96 0.011 0.0612 0.0798
Schistosoma mansoni sodium/chloride dependent transporter 0.0258 0.158 0.206
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0009 0.0011
Echinococcus multilocularis c src tyrosine kinase 0.002 0.0028 0.0037
Brugia malayi hypothetical protein 0.0123 0.0697 0.0697
Trypanosoma brucei proteasome subunit beta type-5, putative 0.1194 0.7668 0.7668
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0232 0.141 0.1839
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0184 0.024
Schistosoma mansoni hypothetical protein 0.0437 0.2742 0.3576
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0018 0.0013 0.0017
Brugia malayi Variant SH3 domain containing protein 0.0016 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0232 0.141 0.141
Giardia lamblia 20S proteasome alpha subunit 7 0.0235 0.1425 0.1859
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0232 0.141 0.1839
Plasmodium falciparum amino acid transporter, putative 0.0044 0.0184 0.024
Loa Loa (eye worm) beta-lactamase 0.0038 0.0149 0.0149
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0235 0.1425 0.1425
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0047 0.0206 0.0257
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.011 0.0612 0.0798
Echinococcus granulosus biogenic amine 5HT receptor 0.0081 0.0427 0.0557
Echinococcus multilocularis proteasome subunit beta type 6 0.0235 0.1425 0.1859
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Loa Loa (eye worm) serotonin transporter b 0.0258 0.158 0.158
Echinococcus multilocularis tyrosine protein kinase Srms 0.0043 0.018 0.0235
Schistosoma mansoni tyrosine kinase 0.0169 0.1001 0.1306
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0235 0.1425 0.1425
Loa Loa (eye worm) hypothetical protein 0.0044 0.0184 0.0184
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0575 0.3639 0.4745
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0104 0.0576 0.0751
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0235 0.1425 0.1859
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0081 0.0427 0.0557
Loa Loa (eye worm) G-protein coupled receptor 0.0081 0.0427 0.0427
Entamoeba histolytica hypothetical protein 0.0038 0.0149 0.0153
Echinococcus multilocularis expressed protein 0.0399 0.2494 0.3252
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0235 0.1425 0.1859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0067 0.0088
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0045 0.0059
Echinococcus granulosus c src tyrosine kinase 0.002 0.0028 0.0037
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0285 0.0371
Brugia malayi sulfakinin receptor protein 0.0081 0.0427 0.0427
Brugia malayi proteasome subunit beta type 2 0.0575 0.3639 0.3639
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0235 0.1425 0.1859
Schistosoma mansoni thyroid hormone receptor 0.0367 0.2286 0.2981
Schistosoma mansoni RAR-like nuclear receptor 0.0232 0.141 0.1839
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0047 0.0206 0.0257
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0211 0.0275
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0235 0.1425 0.1859
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0928 0.5935 0.774
Leishmania major proteasome beta-1 subunit, putative 0.0235 0.1425 0.1425
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0081 0.0081
Brugia malayi Polyprenyl synthetase family protein 0.011 0.0612 0.0612
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0038 0.0148 0.0193
Loa Loa (eye worm) nuclear receptor NHR-67 0.011 0.0612 0.0612
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0032 0.0042
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0032 0.0042
Echinococcus multilocularis dro:myosuppressin receptor 0.0081 0.0427 0.0557
Brugia malayi CXXC zinc finger family protein 0.0031 0.0098 0.0098
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0028 0.0079 0.0102
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0067 0.0088
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0081 0.0427 0.0427
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0032 0.0032
Plasmodium falciparum multidrug resistance protein 1 0.0023 0.0045 0.0059
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0427 0.0557
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0047 0.0206 0.0168
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0045 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Schistosoma mansoni hypothetical protein 0.0033 0.0117 0.0152
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0149 0.0149
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0231 0.0302
Onchocerca volvulus 0.0437 0.2742 1
Leishmania major cytochrome p450-like protein 0.0047 0.0206 0.0206
Toxoplasma gondii peptidase, T1 family protein 0.0235 0.1425 0.1859
Brugia malayi nuclear hormone receptor 0.011 0.0612 0.0612
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0047 0.0206 0.0257
Schistosoma mansoni jun-related protein 0.0073 0.0373 0.0487
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0047 0.0206 0.0257
Loa Loa (eye worm) hypothetical protein 0.0044 0.0184 0.0184
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0235 0.1425 0.1425
Echinococcus granulosus nuclear receptor nhr 48 0.011 0.0612 0.0798
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0009 0.0009
Brugia malayi hypothetical protein 0.0044 0.0184 0.0184
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0149 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0147 0.0192
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0235 0.1425 0.1859
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0235 0.1425 0.1825
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0028 0.0079 0.0079
Leishmania major C-8 sterol isomerase-like protein 0.1552 1 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0232 0.141 0.1839
Schistosoma mansoni polycystin 1-related 0.0021 0.0036 0.0047
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0032 0.0042
Onchocerca volvulus 0.0044 0.0184 0.0556
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0575 0.3639 0.4745
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0231 0.0302
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0235 0.1425 0.1859
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0081 0.0427 0.0557
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0047 0.0206 0.0168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0131 0.0171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0427 0.0557
Schistosoma mansoni neuropeptide f receptor 76f 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.003 0.0097 0.0097
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0235 0.1425 0.1859
Echinococcus multilocularis neuropeptide receptor 0.0081 0.0427 0.0557
Schistosoma mansoni zinc finger protein 0.011 0.0612 0.0798
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0045 0.0059
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus granulosus axis inhibition protein axin 0.002 0.0032 0.0042
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0232 0.141 0.1839
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0044 0.0044
Brugia malayi beta-lactamase family protein 0.0038 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Loa Loa (eye worm) SRC-1 0.0051 0.0231 0.0231
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0135 0.0777 0.1013
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0211 0.0235
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0235 0.1425 0.1425
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0111 0.0144
Echinococcus multilocularis neuropeptide receptor 0.0081 0.0427 0.0557
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0211 0.1274 0.1274
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0215 0.1297 0.1692
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0044 0.0058
Brugia malayi hypothetical protein 0.007 0.0357 0.0357
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0047 0.0206 0.0168
Leishmania major proteasome alpha 2 subunit, putative 0.0235 0.1425 0.1425
Echinococcus granulosus serotonin transporter 0.0258 0.158 0.206
Trypanosoma brucei cardiolipin synthetase 0.0038 0.0148 0.0148
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0258 0.158 0.158
Onchocerca volvulus 0.0081 0.0427 0.1454
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0211 0.0211
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0044 0.0058
Onchocerca volvulus 0.011 0.0612 0.2135
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0235 0.1425 0.1425
Brugia malayi Steroid receptor seven-up type 2 0.0232 0.141 0.141
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.1194 0.7668 1
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0032 0.0042
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0395 0.2472 0.2472
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.1194 0.7668 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Brugia malayi GnHR receptor homolog 0.0081 0.0427 0.0427
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0235 0.1425 0.1859
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0427 0.0557
Loa Loa (eye worm) nuclear hormone receptor 0.011 0.0612 0.0612
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0028 0.0079 0.0079
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0235 0.1425 0.1425
Schistosoma mansoni Lamin B receptor (ERG24) 0.0051 0.0228 0.0297
Plasmodium vivax proteasome subunit beta type-2, putative 0.0575 0.3639 0.4745
Loa Loa (eye worm) PDE1B protein 0.0395 0.2472 0.2472
Toxoplasma gondii NAC domain-containing protein 0.0037 0.0142 0.0185
Onchocerca volvulus 0.0081 0.0427 0.1454
Echinococcus multilocularis tyrosine protein kinase Blk 0.0043 0.018 0.0235
Echinococcus granulosus dnaJ subfamily B 0.0437 0.2742 0.3576
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0147 0.0192
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0047 0.0206 0.0168
Echinococcus granulosus ecdysone induced protein 78C 0.0232 0.141 0.1839
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0173 0.1027 0.134
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0081 0.0427 0.0557
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0047 0.0206 0.0257
Loa Loa (eye worm) hypothetical protein 0.0258 0.158 0.158
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0032 0.0042
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0051 0.0231 0.0302
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0258 0.158 0.206
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0232 0.141 0.1839
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0179 0.0233
Brugia malayi protein-tyrosine kinase 0.0043 0.018 0.018
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0044 0.0184 0.024
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0928 0.5935 0.774
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0235 0.1425 0.1859
Loa Loa (eye worm) ICD-1 protein 0.0037 0.0142 0.0142
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.011 0.0612 0.0612
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0232 0.141 0.141
Schistosoma mansoni gabp alpha 0.0077 0.0402 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0147 0.0192
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0028 0.0079 0.0102
Schistosoma mansoni tyrosine kinase 0.0173 0.1027 0.134
Brugia malayi nuclear receptor NHR-67 0.011 0.0612 0.0612
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0045 0.0059
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0235 0.1425 0.1425
Loa Loa (eye worm) hypothetical protein 0.0123 0.0697 0.0697
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0045 0.0059
Loa Loa (eye worm) PAS-3 protein 0.0235 0.1425 0.1425
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Leishmania major cytochrome p450-like protein 0.0047 0.0206 0.0206
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0044 0.0058
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0235 0.1425 0.1825
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0235 0.1425 0.1859
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0235 0.1425 0.1859
Loa Loa (eye worm) hypothetical protein 0.0232 0.141 0.141
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0036 0.0047
Schistosoma mansoni growth hormone secretagogue receptor 0.0081 0.0427 0.0557
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.011 0.0612 0.0798
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0081 0.0427 0.0557
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0179 0.0233
Onchocerca volvulus 0.0038 0.0149 0.0426
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0235 0.1425 0.1859
Brugia malayi isocitrate dehydrogenase 0.0017 0.0009 0.0009
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.002 0.0028 0.0037
Schistosoma mansoni biogenic amine (5HT) receptor 0.0211 0.1274 0.1662
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0028 0.0079 0.0463
Onchocerca volvulus Peroxidasin homolog 0.0028 0.0081 0.0177
Loa Loa (eye worm) hypothetical protein 0.0038 0.0149 0.0149
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0235 0.1425 0.1859
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0235 0.1425 0.1425
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0003 0.0003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0081 0.0427 0.0557
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0427 0.0557
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0928 0.5935 0.774
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0232 0.141 0.141
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0045
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0232 0.141 0.1839
Trypanosoma cruzi C-14 sterol reductase, putative 0.0051 0.0228 0.0228
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0032 0.0042
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0023 0.0045 0.0045
Trichomonas vaginalis ran, putative 0.0022 0.0044 0.0058
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.011 0.0612 0.0798
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0135 0.0777 0.1013
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0149 0.0183
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Brugia malayi Phospholipase D. Active site motif family protein 0.0021 0.0034 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0067 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0232 0.141 0.141
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0047 0.0206 0.0257
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0149 0.0194
Brugia malayi PXA domain containing protein 0.0025 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0036
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0017 0.0022
Brugia malayi nuclear receptor RXR 0.011 0.0612 0.0612
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0097 0.0097
Echinococcus granulosus tyrosine protein kinase Lyn 0.0051 0.0231 0.0302
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0138 0.018
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0235 0.1425 0.1425
Loa Loa (eye worm) hypothetical protein 0.0258 0.158 0.158
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0051 0.0231 0.0302
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0023 0.0045 0.1879
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0028 0.0079 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Echinococcus multilocularis conserved hypothetical protein 0.0737 0.4696 0.6124
Brugia malayi Cytochrome P450 family protein 0.0088 0.0471 0.0471
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0009 0.0009
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.002 0.0028 0.0037
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0036 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0131 0.0171
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0232 0.141 0.141
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.0128 0.0167
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0045 0.0059
Loa Loa (eye worm) solute carrier family 6 member 4 0.0258 0.158 0.158
Echinococcus granulosus insulin receptor 0.0104 0.0576 0.0751
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0966 0.6184 0.8065
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0184 0.024
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0045 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0034 0.0121 0.0121
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0009 0.0011
Treponema pallidum sodium- and chloride- dependent transporter 0.0258 0.158 1
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1077 0.1404
Schistosoma mansoni ran 0.0022 0.0044 0.0058
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0235 0.1425 0.1825
Brugia malayi ABC transporter family protein 0.0023 0.0045 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0131 0.0171
Toxoplasma gondii ABC1 family protein 0.0038 0.0149 0.0194
Entamoeba histolytica hypothetical protein 0.0038 0.0149 0.0153
Onchocerca volvulus 0.0081 0.0427 0.1454
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0028 0.0079 0.0102
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0235 0.1425 0.1425
Schistosoma mansoni hypothetical protein 0.0033 0.0117 0.0152
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0047 0.0206 0.0257
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Schistosoma mansoni neuropeptide receptor 0.0081 0.0427 0.0557
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0085 0.0111
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0047 0.0206 0.0168
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0235 0.1425 0.1859
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus granulosus g-protein coupled receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0081 0.0081
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Loa Loa (eye worm) DR-78 0.011 0.0612 0.0612
Schistosoma mansoni adapter molecule crk 0.0016 0.0002 0.0003
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0211 0.0211
Echinococcus multilocularis proteasome subunit alpha type 2 0.0235 0.1425 0.1859
Echinococcus granulosus tyrosine protein kinase Src42A 0.0051 0.0231 0.0302
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0117 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0067 0.0088
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0235 0.1425 0.1859
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0184 0.024
Schistosoma mansoni growth factor receptor-bound protein 0.0016 0.0002 0.0003
Echinococcus multilocularis transcription factor btf3 0.0037 0.0142 0.0185
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.009 0.0482 0.0629
Trypanosoma cruzi cytochrome P450, putative 0.0074 0.038 0.038
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0081 0.0427 0.0427
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.011 0.0612 0.0787
Onchocerca volvulus 0.011 0.0612 0.2135
Onchocerca volvulus 0.0081 0.0427 0.1454
Onchocerca volvulus 0.0028 0.0081 0.0177
Brugia malayi nuclear hormone receptor family member odr-7 0.011 0.0612 0.0612
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0232 0.141 0.141
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0232 0.141 0.141
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0111 0.0144
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0111 0.0144
Leishmania major farnesyl pyrophosphate synthase 0.011 0.0612 0.0612
Giardia lamblia 20S proteasome alpha subunit 4 0.0235 0.1425 0.1859
Loa Loa (eye worm) hypothetical protein 0.0044 0.0184 0.0184
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0235 0.1425 0.1859
Brugia malayi Furin-like cysteine rich region family protein 0.0321 0.1987 0.1987
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0235 0.1425 0.1425
Onchocerca volvulus 0.0023 0.0045 0.0043
Onchocerca volvulus 0.0081 0.0427 0.1454
Echinococcus granulosus cpg binding protein 0.0032 0.011 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0131 0.0171
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0437 0.2742 0.2742
Leishmania major proteasome alpha 1 subunit, putative 0.0235 0.1425 0.1425
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Schistosoma mansoni tyrosine kinase 0.0169 0.1001 0.1306
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0149 0.0093
Echinococcus granulosus multidrug resistance protein 1 0.0016 0.0001 0.0001
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0149 0.0194
Schistosoma mansoni sodium-dependent amino acid transporter 0.0044 0.0184 0.024
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0045 0.0059
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.1552 1 1
Plasmodium vivax proteasome subunit beta type-6, putative 0.0235 0.1425 0.1859
Schistosoma mansoni tyrosine kinase 0.002 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0235 0.1425 0.1825
Brugia malayi Serotonin receptor 0.0573 0.3626 0.3626
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0135 0.0777 0.1013
Brugia malayi Nuclear hormone receptor-like 1 0.0123 0.0697 0.0697
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1077 0.1404
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0575 0.3639 0.4745
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0232 0.141 0.141
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0032 0.0032
Echinococcus granulosus FTZ F1 alpha 0.0232 0.141 0.1839
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0149 0.0183
Echinococcus granulosus biogenic amine 5HT receptor 0.0211 0.1274 0.1662
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1077 0.1404
Loa Loa (eye worm) hypothetical protein 0.0123 0.0697 0.0697
Onchocerca volvulus Dual oxidase homolog 0.0028 0.0081 0.0177
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0028 0.0079 0.0079
Brugia malayi Nuclear hormone receptor-like 1 0.0232 0.141 0.141
Loa Loa (eye worm) hypothetical protein 0.0038 0.0149 0.0149
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0016 0.0001 0.0001
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0032 0.0042
Trypanosoma cruzi Emopamil binding protein, putative 0.0437 0.2742 0.2742
Leishmania major hypothetical protein, conserved 0.0437 0.2742 0.2742
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0059 0.0077
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0235 0.1425 0.185
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0232 0.141 0.141
Schistosoma mansoni adenoreceptor 0.0081 0.0427 0.0557
Echinococcus multilocularis multidrug resistance protein 1 0.0016 0.0001 0.0001
Leishmania major proteasome alpha 7 subunit, putative 0.0235 0.1425 0.1425
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Onchocerca volvulus 0.0044 0.0184 0.0556
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0235 0.1425 0.1859
Brugia malayi Proteasome A-type and B-type family protein 0.0235 0.1425 0.1425
Echinococcus granulosus axis inhibition protein axin 0.002 0.0032 0.0042
Brugia malayi Proteasome A-type and B-type family protein 0.0235 0.1425 0.1425
Onchocerca volvulus 0.0232 0.141 0.5084
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.033 0.043
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0235 0.1425 0.1425
Echinococcus granulosus 7tm_1 domain containing protein 0.0081 0.0427 0.0557
Echinococcus granulosus tyrosine protein kinase Btk29A 0.002 0.0028 0.0037
Echinococcus granulosus snurportin 1 0.0325 0.2012 0.2623
Loa Loa (eye worm) PXA domain-containing protein 0.0025 0.0063 0.0063
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.0587 0.0587
Loa Loa (eye worm) blistered cuticle protein 3 0.0028 0.0081 0.0081
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0235 0.1425 0.1425
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0042
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0235 0.1425 0.1859
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0081 0.0081
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0009 0.0011
Giardia lamblia 20S proteasome alpha subunit 5 0.0235 0.1425 0.1859
Trypanosoma brucei Emopamil binding protein, putative 0.0437 0.2742 0.2742
Echinococcus granulosus GA binding protein alpha chain 0.0077 0.0402 0.0524
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0235 0.1425 0.1859
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Trypanosoma brucei proteasome beta 7 subunit 0.0235 0.1425 0.1425
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1194 0.7668 0.7668
Brugia malayi hypothetical protein 0.0081 0.0427 0.0427
Onchocerca volvulus 0.0033 0.0111 0.0284
Brugia malayi proteasome subunit alpha type 2 0.0235 0.1425 0.1425
Brugia malayi Dopamine receptor protein 1 0.0081 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Schistosoma mansoni nck2/grb4 0.0016 0.0002 0.0003
Echinococcus multilocularis tyrosine protein kinase Abl 0.002 0.0028 0.0037
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0032 0.0032
Leishmania major cardiolipin synthetase, putative 0.0018 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0232 0.141 0.141
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Brugia malayi proteasome subunit beta type 3 0.0235 0.1425 0.1425
Brugia malayi cytochrome P450 0.0047 0.0206 0.0206
Onchocerca volvulus 0.0081 0.0427 0.1454
Brugia malayi Variant SH3 domain containing protein 0.0016 0.0002 0.0002
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0211 0.0211
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0235 0.1425 0.1859
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0427 0.0557
Brugia malayi orphan nuclear receptor NR2E1 0.011 0.0612 0.0612
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0131 0.0171
Brugia malayi Cytochrome P450 family protein 0.0047 0.0206 0.0206
Loa Loa (eye worm) cytochrome P450 family protein 0.0074 0.038 0.038
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0111 0.0144
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Entamoeba histolytica hypothetical protein 0.0038 0.0149 0.0153
Loa Loa (eye worm) hypothetical protein 0.0044 0.0184 0.0184
Echinococcus multilocularis peroxidasin 0.0028 0.0081 0.0106
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0135 0.0777 0.0777
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0235 0.1425 0.1859
Echinococcus granulosus proteasome subunit alpha type 6 0.0235 0.1425 0.1859
Loa Loa (eye worm) cytochrome P450 family protein 0.0074 0.038 0.038
Echinococcus granulosus epidermal growth factor receptor 0.0321 0.1987 0.2591
Giardia lamblia Proteasome subunit beta type 5 precursor 0.1194 0.7668 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0149 0.0149
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0235 0.1425 0.1425
Echinococcus granulosus proteasome subunit beta t family 0.0235 0.1425 0.1859
Giardia lamblia Proteasome subunit beta type 2 0.0575 0.3639 0.4745
Echinococcus multilocularis G protein coupled receptor 139 0.0081 0.0427 0.0557
Brugia malayi beta-lactamase 0.0038 0.0149 0.0149
Loa Loa (eye worm) CYP4Cod1 0.0074 0.038 0.038
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0184 0.024
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0047 0.0206 0.0257
Schistosoma mansoni amine GPCR 0.0435 0.273 0.3561
Trichomonas vaginalis abcb9, putative 0.0023 0.0045 0.0059
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0045 0.0059
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0081 0.0427 0.1454
Echinococcus multilocularis fmrfamide receptor 0.0081 0.0427 0.0557
Schistosoma mansoni farnesyl pyrophosphate synthase 0.011 0.0612 0.0798
Plasmodium vivax basic transcription factor 3b, putative 0.0037 0.0142 0.0185
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0184 0.024
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.0155 0.0202
Echinococcus multilocularis proteasome (prosome, macropain) 0.1194 0.7668 1
Leishmania major proteasome alpha 7 subunit, putative 0.0235 0.1425 0.1425
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0123 0.0697 0.0697
Schistosoma mansoni hypothetical protein 0.0134 0.0774 0.1009
Echinococcus multilocularis neuropeptide FF receptor 2 0.0081 0.0427 0.0557
Plasmodium vivax proteasome subunit beta type-1, putative 0.0928 0.5935 0.774
Brugia malayi ecdysone receptor 0.011 0.0612 0.0612
Brugia malayi Melatonin receptor type 1A 0.0081 0.0427 0.0427
Brugia malayi Pre-SET motif family protein 0.0033 0.0111 0.0111
Toxoplasma gondii hypothetical protein 0.0044 0.0184 0.024
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0045 0.0059
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0017 0.0022
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0042
Loa Loa (eye worm) norepinephrine transporter 0.0258 0.158 0.158
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0184 0.024
Brugia malayi Doublecortin family protein 0.0021 0.0036 0.0036
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Plasmodium vivax proteasome subunit beta type-5, putative 0.1194 0.7668 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0427 0.0427
Echinococcus multilocularis epidermal growth factor receptor 0.0321 0.1987 0.2591
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0235 0.1425 0.1859
Onchocerca volvulus 0.0258 0.158 0.5709
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0232 0.141 0.1839
Brugia malayi Serotonin receptor 0.0081 0.0427 0.0427
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0081 0.0427 0.0557
Loa Loa (eye worm) hypothetical protein 0.011 0.0612 0.0612
Loa Loa (eye worm) hypothetical protein 0.0092 0.0499 0.0499
Loa Loa (eye worm) steroid hormone receptor 0.0232 0.141 0.141
Loa Loa (eye worm) hypothetical protein 0.0232 0.141 0.141
Giardia lamblia GTOR 0.0048 0.0211 0.0275
Echinococcus granulosus tm gpcr rhodopsin 0.0966 0.6184 0.8065
Loa Loa (eye worm) hypothetical protein 0.0038 0.0149 0.0149
Onchocerca volvulus 0.007 0.0357 0.1195
Echinococcus granulosus nuclear receptor 2DBD gamma 0.011 0.0612 0.0798
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0047 0.0206 0.0168

Activities

Activity type Activity value Assay description Source Reference
IC90 (functional) = 19.1 ug ml-1 Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 microplate alamar blue assay ChEMBL. 20656380

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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