Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.029 | 0.5169 | 0.5169 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0397 | 0.8826 | 0.8826 |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 1 | 1 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0348 | 0.7164 | 0.7164 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0348 | 0.7164 | 0.7164 |
Trypanosoma cruzi | AMP deaminase, putative | 0.014 | 0 | 0.5 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0397 | 0.8826 | 0.8826 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0431 | 1 | 0.5 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0397 | 0.8826 | 0.8826 |
Loa Loa (eye worm) | hypothetical protein | 0.0397 | 0.8826 | 0.8826 |
Loa Loa (eye worm) | hypothetical protein | 0.029 | 0.5169 | 0.5169 |
Leishmania major | adenine aminohydrolase | 0.0431 | 1 | 1 |
Plasmodium falciparum | adenosine deaminase | 0.0431 | 1 | 1 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0348 | 0.7164 | 0.7164 |
Trypanosoma cruzi | AMP deaminase, putative | 0.014 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.014 | 0 | 0.5 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0397 | 0.8826 | 0.8826 |
Trypanosoma cruzi | AMP deaminase, putative | 0.014 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.014 | 0 | 0.5 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0397 | 0.8826 | 0.5 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0431 | 1 | 0.5 |
Echinococcus multilocularis | adenosine deaminase | 0.0431 | 1 | 1 |
Mycobacterium ulcerans | adenosine deaminase | 0.0431 | 1 | 0.5 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0397 | 0.8826 | 0.8826 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0431 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.029 | 0.5169 | 0.5169 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0431 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.029 | 0.5169 | 0.5169 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.014 | 0 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0431 | 1 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.014 | 0 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.014 | 0 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.0431 | 1 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0348 | 0.7164 | 0.7164 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0431 | 1 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.014 | 0 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.014 | 0 | 0.5 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0397 | 0.8826 | 0.8826 |
Schistosoma mansoni | adenosine deaminase | 0.0431 | 1 | 1 |
Trypanosoma brucei | AMP deaminase, putative | 0.014 | 0 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0431 | 1 | 1 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0431 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase 2, putative | 0.014 | 0 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0431 | 1 | 1 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0431 | 1 | 1 |
Treponema pallidum | adenosine deaminase | 0.0431 | 1 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.0431 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.