Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | vivapain-2 | 0.002 | 0.1472 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.4958 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.002 | 0.1472 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0468 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.002 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.002 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.002 | 0.1472 | 1 |
Brugia malayi | hypothetical protein | 0.0042 | 0.4958 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0075 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0075 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.002 | 0.1472 | 0.2968 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.002 | 0.1472 | 0.2968 |
Loa Loa (eye worm) | fibroinase | 0.002 | 0.1472 | 1 |
Onchocerca volvulus | 0.002 | 0.1472 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Echinococcus multilocularis | cysteine protease | 0.002 | 0.1472 | 0.2968 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.4958 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.002 | 0.1472 | 0.2968 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0068 | 0.8997 | 0.8997 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.002 | 0.1472 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0013 | 0.0468 | 0.0944 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.1472 | 0.2968 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0013 | 0.0468 | 0.0944 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.002 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.1472 | 0.2968 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.002 | 0.1472 | 0.2968 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.002 | 0.1472 | 0.2968 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.4958 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.002 | 0.1472 | 0.2968 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.002 | 0.1472 | 0.1472 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.1472 | 0.2968 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.4958 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0468 | 0.0944 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.4958 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.1472 | 0.2968 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0468 | 0.0944 |
Entamoeba histolytica | cysteine proteinase, putative | 0.002 | 0.1472 | 0.2968 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.002 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 1 | 1 |
Onchocerca volvulus | 0.002 | 0.1472 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.1472 | 0.2968 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0013 | 0.0468 | 0.0944 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.4958 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.4958 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 1 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0059 | 0.7525 | 0.7525 |
Onchocerca volvulus | Cathepsin F homolog | 0.002 | 0.1472 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.002 | 0.1472 | 0.2968 |
Brugia malayi | cathepsin L-like precursor | 0.0013 | 0.0468 | 0.0944 |
Loa Loa (eye worm) | ctsf protein | 0.002 | 0.1472 | 1 |
Onchocerca volvulus | 0.002 | 0.1472 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Onchocerca volvulus | 0.002 | 0.1472 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.1472 | 0.2968 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.002 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.1472 | 0.2968 |
Echinococcus granulosus | cathepsin l1 | 0.002 | 0.1472 | 0.2968 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 1 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.002 | 0.1472 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.1472 | 0.2968 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0468 | 0.3182 |
Onchocerca volvulus | 0.002 | 0.1472 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.002 | 0.1472 | 0.2968 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0013 | 0.0468 | 0.0944 |
Onchocerca volvulus | 0.002 | 0.1472 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0075 | 1 | 1 |
Onchocerca volvulus | 0.002 | 0.1472 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.002 | 0.1472 | 0.2968 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.002 | 0.1472 | 1 |
Plasmodium vivax | vivapain-2 | 0.002 | 0.1472 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.002 | 0.1472 | 0.2968 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.4958 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.