Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | dipeptidyl-peptidase 4 | Starlite/ChEMBL | References |
Homo sapiens | dipeptidyl-peptidase 8 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0276 | 0.1261 | 0.1261 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0208 | 0.0864 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0276 | 0.1261 | 0.0434 |
Echinococcus granulosus | neural cadherin | 0.0276 | 0.1261 | 0.1261 |
Echinococcus granulosus | slit 2 protein | 0.0276 | 0.1261 | 0.1261 |
Schistosoma mansoni | notch | 0.0276 | 0.1261 | 0.0434 |
Schistosoma mansoni | peroxidasin | 0.1776 | 1 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Echinococcus granulosus | protein jagged 2 | 0.0276 | 0.1261 | 0.1261 |
Brugia malayi | Animal haem peroxidase family protein | 0.1776 | 1 | 1 |
Brugia malayi | Peroxidasin | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Echinococcus multilocularis | fibropellin Ia | 0.0276 | 0.1261 | 0.1261 |
Onchocerca volvulus | Peroxidase homolog | 0.1776 | 1 | 1 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0276 | 0.1261 | 0.1261 |
Brugia malayi | Animal haem peroxidase family protein | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.028 | 0.0043 |
Onchocerca volvulus | Dual oxidase homolog | 0.1776 | 1 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0208 | 0.0864 | 0.0864 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.028 | 0.1282 | 0.0024 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0276 | 0.1261 | 0.1261 |
Schistosoma mansoni | notch | 0.0276 | 0.1261 | 0.0434 |
Brugia malayi | Cadherin domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Brugia malayi | EGF-like domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Schistosoma mansoni | notch | 0.0276 | 0.1261 | 0.0434 |
Brugia malayi | Delta serrate ligand family protein | 0.0276 | 0.1261 | 0.1009 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.028 | 0.1282 | 0.0457 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.028 | 0.1282 | 0.1282 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0276 | 0.1261 | 0.1009 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.1776 | 1 | 1 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0276 | 0.1261 | 0.1261 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Echinococcus multilocularis | slit 2 protein | 0.0276 | 0.1261 | 0.1261 |
Echinococcus multilocularis | peroxidasin | 0.1776 | 1 | 1 |
Schistosoma mansoni | slit | 0.0276 | 0.1261 | 0.0434 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.028 | 0.1282 | 0.1282 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Schistosoma mansoni | hypothetical protein | 0.0276 | 0.1261 | 0.0434 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Schistosoma mansoni | peroxidasin | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Brugia malayi | EGF-like domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Schistosoma mansoni | notch | 0.0276 | 0.1261 | 0.0434 |
Schistosoma mansoni | notch | 0.0276 | 0.1261 | 0.0434 |
Schistosoma mansoni | notch | 0.0276 | 0.1261 | 0.0434 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0276 | 0.1261 | 0.1261 |
Brugia malayi | EGF-like domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Brugia malayi | EGF-like domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Brugia malayi | notch-like transmembrane receptor | 0.0276 | 0.1261 | 0.1009 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0208 | 0.0864 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Schistosoma mansoni | hypothetical protein | 0.0276 | 0.1261 | 0.0434 |
Loa Loa (eye worm) | animal heme peroxidase | 0.1776 | 1 | 1 |
Echinococcus granulosus | notch | 0.0276 | 0.1261 | 0.1261 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Echinococcus multilocularis | notch | 0.0276 | 0.1261 | 0.1261 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0208 | 0.0864 | 0.5 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.028 | 0.1282 | 0.1069 |
Schistosoma mansoni | hypothetical protein | 0.0276 | 0.1261 | 0.0434 |
Brugia malayi | Muscle positioning protein 4 | 0.0276 | 0.1261 | 0.1009 |
Brugia malayi | Animal haem peroxidase family protein | 0.1776 | 1 | 1 |
Schistosoma mansoni | septate junction protein | 0.0276 | 0.1261 | 0.0434 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0208 | 0.0864 | 0.0602 |
Echinococcus granulosus | protein jagged 1 | 0.0276 | 0.1261 | 0.1261 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0208 | 0.0864 | 0.5 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Onchocerca volvulus | Peroxidase homolog | 0.1776 | 1 | 1 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.0456 | 0.2312 | 0.1584 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0276 | 0.1261 | 0.1261 |
Brugia malayi | EGF-like domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Brugia malayi | prolyl oligopeptidase family protein | 0.028 | 0.1282 | 0.1031 |
Echinococcus granulosus | fibropellin Ia | 0.0276 | 0.1261 | 0.1261 |
Loa Loa (eye worm) | Notch2 | 0.0276 | 0.1261 | 0.1048 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.1776 | 1 | 1 |
Echinococcus multilocularis | neural cadherin | 0.0276 | 0.1261 | 0.1261 |
Onchocerca volvulus | 0.1776 | 1 | 1 | |
Echinococcus multilocularis | protein jagged 1 | 0.0276 | 0.1261 | 0.1261 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.0456 | 0.2312 | 0.2312 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0276 | 0.1261 | 0.1009 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Schistosoma mansoni | hypothetical protein | 0.0276 | 0.1261 | 0.0434 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0456 | 0.2312 | 0.2312 |
Giardia lamblia | High cysteine protein | 0.0276 | 0.1261 | 0.5 |
Echinococcus multilocularis | protein jagged 1 | 0.0276 | 0.1261 | 0.1261 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.1776 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0276 | 0.1261 | 0.1261 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Loa Loa (eye worm) | animal heme peroxidase | 0.1776 | 1 | 1 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0276 | 0.1261 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Echinococcus granulosus | protein jagged 2 | 0.0276 | 0.1261 | 0.1261 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Echinococcus granulosus | delta-like protein 1 | 0.0276 | 0.1261 | 0.1261 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Onchocerca volvulus | 0.1776 | 1 | 1 | |
Brugia malayi | Blistered cuticle protein 3 | 0.1776 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0276 | 0.1261 | 0.1261 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0276 | 0.1261 | 0.1261 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0208 | 0.0864 | 0.0864 |
Onchocerca volvulus | Peroxidasin homolog | 0.1776 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Onchocerca volvulus | 0.1776 | 1 | 1 | |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0208 | 0.0864 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Echinococcus granulosus | peroxidasin | 0.1776 | 1 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.0276 | 0.1261 | 0.1261 |
Schistosoma mansoni | hypothetical protein | 0.0276 | 0.1261 | 0.0434 |
Loa Loa (eye worm) | hypothetical protein | 0.1776 | 1 | 1 |
Schistosoma mansoni | cell polarity protein | 0.0276 | 0.1261 | 0.0434 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0276 | 0.1261 | 0.0434 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Schistosoma mansoni | hypothetical protein | 0.0276 | 0.1261 | 0.0434 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0276 | 0.1261 | 0.1261 |
Loa Loa (eye worm) | animal heme peroxidase | 0.1776 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.1261 | 0.1048 |
Loa Loa (eye worm) | notch protein | 0.0276 | 0.1261 | 0.1048 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0276 | 0.1261 | 0.1009 |
Echinococcus multilocularis | protein jagged 2 | 0.0276 | 0.1261 | 0.1261 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0276 | 0.1261 | 0.0434 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.