Detailed information for compound 980431

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 361.394 | Formula: C21H19N3O3
  • H donors: 2 H acceptors: 3 LogP: 2.86 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)C(=O)Nc1ccc(c(c1)C(=O)Nc1cccnc1)C
  • InChi: 1S/C21H19N3O3/c1-14-5-8-16(23-20(25)15-6-9-18(27-2)10-7-15)12-19(14)21(26)24-17-4-3-11-22-13-17/h3-13H,1-2H3,(H,23,25)(H,24,26)
  • InChiKey: RWIWGVKYQLNBEX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0019 0.0005 0.0014
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0029 0.0029
Echinococcus granulosus somatostatin receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) DR-78 0.0019 0.0006 0.0006
Brugia malayi nuclear receptor NHR-88 0.0019 0.0006 0.0006
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0006 0.0006
Schistosoma mansoni ferritin 0.0019 0.0005 0.0005
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0004 0.0045
Loa Loa (eye worm) glutaminase 0.0267 0.0378 0.0378
Onchocerca volvulus 0.0042 0.0039 0.0202
Echinococcus granulosus lamin 0.0027 0.0017 0.0017
Plasmodium falciparum DNA gyrase subunit B 0.0081 0.0098 0.1242
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0036
Plasmodium vivax thioredoxin reductase, putative 0.0106 0.0136 0.1741
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0039 0.0232
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0027 0.0027
Brugia malayi glutathione reductase 0.0106 0.0136 0.0136
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.002 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.0006
Brugia malayi Thioredoxin reductase 0.0106 0.0136 0.0136
Brugia malayi neuropeptide F receptor 0.002 0.0006 0.0006
Schistosoma mansoni ferritin 0.0019 0.0005 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0117 0.0696
Schistosoma mansoni ferritin 0.0019 0.0005 0.0005
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0065 0.0075 0.1704
Echinococcus granulosus sex peptide receptor 0.002 0.0006 0.0006
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.002 0.0006 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0006 0.0006
Trichomonas vaginalis mercuric reductase, putative 0.0037 0.0032 0.0188
Loa Loa (eye worm) hypothetical protein 0.0049 0.0051 0.0051
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0039 0.0039
Schistosoma mansoni gliotactin 0.1125 0.167 0.167
Loa Loa (eye worm) RNA binding protein 0.0142 0.019 0.019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0036
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Toxoplasma gondii NADPH-glutathione reductase 0.0037 0.0032 0.1146
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0131 0.0174 0.329
Onchocerca volvulus 0.0027 0.0017 0.0066
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0221 0.0309 0.3609
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.0117 0.0668
Brugia malayi ecdysone receptor 0.0019 0.0006 0.0006
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0031 0.0024 0.0258
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0037 0.0032 0.1146
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0015 0.0075
Schistosoma mansoni cpg binding protein 0.0035 0.0029 0.0029
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0017 0.0017
Plasmodium vivax ubiquitin activating enzyme, putative 0.0047 0.0048 0.0581
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0004 0.0004
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0799 0.1179 0.1179
Brugia malayi hypothetical protein 0.0121 0.0158 0.0158
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0043 0.0042 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0006 0.0006
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0037 0.0032 0.0174
Echinococcus granulosus expressed protein 0.0019 0.0005 0.0005
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0091 0.0539
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.003 0.0021 0.0387
Loa Loa (eye worm) hypothetical protein 0.1125 0.167 0.167
Echinococcus granulosus acetylcholinesterase 0.6658 1 1
Schistosoma mansoni neuropeptide receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Brugia malayi CXXC zinc finger family protein 0.0033 0.0027 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0038 0.0038
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0117 0.0117
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0038 0.0038
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0073 0.0087 0.3308
Echinococcus multilocularis expressed conserved protein 0.0207 0.0289 0.0289
Loa Loa (eye worm) acetylcholinesterase 1 0.6658 1 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0037 0.0032 0.0634
Echinococcus multilocularis musashi 0.0027 0.0017 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Echinococcus multilocularis muscleblind protein 0.0147 0.0198 0.0198
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0087 0.1608
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0006 0.0006
Echinococcus granulosus 7tm_1 domain containing protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.1125 0.167 0.167
Plasmodium falciparum thioredoxin reductase 0.0106 0.0136 0.1741
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0846 0.5066
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0006 0.0006
Mycobacterium ulcerans carboxylesterase, LipT 0.1125 0.167 1
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0006 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0117 0.0696
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0005 0.0044
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0006 0.0006
Echinococcus multilocularis orexin receptor type 2 0.002 0.0006 0.0006
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0038 0.0195
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0019 0.0005 0.0053
Trichomonas vaginalis glucosylceramidase, putative 0.038 0.0548 0.3281
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0242 0.0341 0.2025
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0006 0.0006
Schistosoma mansoni apoferritin-2 0.0019 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0039 0.0217
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0006 0.0006
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.002 0.0006 0.0006
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0006 0.0006
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0006 0.0016
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0006 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0006 0.0006
Plasmodium vivax DNA topoisomerase II, putative 0.0139 0.0185 0.2388
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0038
Brugia malayi RNA recognition motif domain containing protein 0.0142 0.019 0.019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0039 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0006 0.0006
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0091 0.0539
Brugia malayi Melatonin receptor type 1A 0.002 0.0006 0.0006
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0007 0.0036
Echinococcus multilocularis thioredoxin glutathione reductase 0.0106 0.0136 0.0136
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0006 0.0006
Echinococcus multilocularis g protein coupled receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0048 0.0048
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0038 0.0038
Echinococcus granulosus g-protein coupled receptor 0.002 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0035 0.003 0.0294
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus allatostatin A receptor 0.002 0.0006 0.0006
Onchocerca volvulus Huntingtin homolog 0.0121 0.0158 0.0917
Echinococcus multilocularis conserved hypothetical protein 0.068 0.1 0.1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0266 0.0377 0.2241
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Schistosoma mansoni ferritin light chain 0.0019 0.0005 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Echinococcus multilocularis geminin 0.038 0.0548 0.0548
Onchocerca volvulus 0.0033 0.0027 0.0126
Brugia malayi Cytochrome P450 family protein 0.0035 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0038 0.0038
Schistosoma mansoni chromobox protein 0.0076 0.0091 0.0091
Brugia malayi G protein-coupled receptor 0.002 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0034 0.0027 0.0027
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0015
Toxoplasma gondii thioredoxin reductase 0.0106 0.0136 0.5272
Trichomonas vaginalis Sentrin-specific protease, putative 0.0065 0.0075 0.0447
Echinococcus granulosus g protein coupled receptor 0.002 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0006 0.0006
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0065 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0162 0.022 0.022
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0005 0.0014
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0038 0.0038
Onchocerca volvulus 0.002 0.0006 0.0002
Onchocerca volvulus 0.0095 0.012 0.0688
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0015 0.0119
Brugia malayi AKH receptor 0.002 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Plasmodium vivax DNA gyrase subunit B, putative 0.0081 0.0098 0.1242
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0032 0.0557
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0038 0.0038
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0006 0.0006
Brugia malayi Cell division protein ftsZ 0.0143 0.0192 0.0192
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0006 0.0006
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0038 0.0038
Loa Loa (eye worm) glutaminase 2 0.0267 0.0378 0.0378
Onchocerca volvulus Glucosylceramidase homolog 0.038 0.0548 0.326
Plasmodium vivax DNA gyrase subunit A, putative 0.003 0.0021 0.0229
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0005 0.0014
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0015 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0046 0.0272
Onchocerca volvulus 0.0036 0.003 0.0149
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0006 0.0006
Echinococcus multilocularis sterol regulatory element binding protein 0.0095 0.0119 0.0119
Echinococcus granulosus tar DNA binding protein 0.0142 0.019 0.019
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0027 0.0027
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0039 0.0232
Brugia malayi nuclear receptor NHR-88 0.0041 0.0038 0.0038
Brugia malayi nuclear hormone receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0038 0.0038
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0037 0.0032 0.0032
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0006 0.0006
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Trypanosoma cruzi DNA topoisomerase II, putative 0.0131 0.0174 0.329
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0084 0.0104 0.1935
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0087 0.0515
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0467 0.068 0.068
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0363 0.0523 0.0523
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni neuropeptide receptor 0.002 0.0006 0.0006
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0006 0.0006
Echinococcus granulosus Niemann Pick C1 protein 0.0221 0.0309 0.0309
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0031 0.0024 0.0024
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1125 0.167 0.167
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0139 0.0185 0.0185
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0242 0.0341 0.2025
Echinococcus granulosus neuropeptide receptor 0.002 0.0006 0.0006
Brugia malayi Cytochrome P450 family protein 0.0017 0.0003 0.0003
Brugia malayi Inositol-1 0.0073 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi Muscleblind-like protein 0.0147 0.0198 0.0198
Schistosoma mansoni DNA topoisomerase type I 0.0185 0.0256 0.0256
Brugia malayi TAR-binding protein 0.0142 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0004 0.0022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0009
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.002 0.0006 0.0006
Echinococcus multilocularis dro:myosuppressin receptor 0.002 0.0006 0.0006
Leishmania major hypothetical protein, conserved 0.0025 0.0014 0.0206
Schistosoma mansoni tsg101-related 0.0057 0.0062 0.0062
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0065 0.0075 0.0831
Plasmodium vivax telomerase reverse transcriptase, putative 0.0522 0.0763 1
Loa Loa (eye worm) carboxylesterase 0.1125 0.167 0.167
Mycobacterium ulcerans cell division protein FtsZ 0.0298 0.0426 0.2536
Echinococcus granulosus chromobox protein 1 0.0076 0.0091 0.0091
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0006 0.0006
Mycobacterium tuberculosis Carboxylesterase LipT 0.1125 0.167 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.002 0.0006 0.0006
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0037 0.0032 0.0557
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi hypothetical protein 0.0019 0.0006 0.0006
Onchocerca volvulus 0.002 0.0006 0.0002
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0015 0.0147
Onchocerca volvulus 0.002 0.0006 0.0002
Echinococcus multilocularis 0.0017 0.0003 0.0003
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0006 0.0006
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0044 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0032 0.0557
Echinococcus granulosus carboxylesterase 5A 0.6658 1 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0006 0.0006
Brugia malayi hypothetical protein 0.0022 0.0009 0.0009
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0242 0.0341 0.2025
Loa Loa (eye worm) hypothetical protein 0.1125 0.167 0.167
Trichomonas vaginalis conserved hypothetical protein 0.0095 0.0119 0.0711
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0006 0.0006
Mycobacterium ulcerans beta-lactamase 0.0042 0.0039 0.0217
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0015 0.0486
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0038 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0004 0.0006
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0004 0.0004
Trichomonas vaginalis esterase, putative 0.0042 0.0039 0.0232
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0038
Mycobacterium tuberculosis Probable dehydrogenase 0.0242 0.0341 0.2025
Brugia malayi hypoxia-induced factor 1 0.0149 0.0201 0.0201
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0038 0.0038
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0015 0.0121
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0044 0.0044
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0015 0.0294
Schistosoma mansoni nuclear receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0147 0.0198 0.0198
Brugia malayi Dopamine receptor protein 1 0.002 0.0006 0.0006
Onchocerca volvulus 0.0033 0.0027 0.0127
Echinococcus granulosus g protein coupled receptor 0.002 0.0006 0.0006
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0045 0.0268
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0097 0.0123 0.1404
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0006 0.0006
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0004 0.0004
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0037 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Mycobacterium tuberculosis Conserved protein 0.0042 0.0039 0.0217
Echinococcus multilocularis neuropeptide receptor 0.002 0.0006 0.0006
Echinococcus multilocularis g-protein coupled receptor 0.002 0.0006 0.0006
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.002 0.0006 0.0083
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0038 0.0038
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.003 0.003
Onchocerca volvulus 0.1125 0.167 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0038 0.0038
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0006 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0117 0.0696
Echinococcus granulosus DNA topoisomerase 1 0.0185 0.0256 0.0256
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0037 0.0032 0.0557
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0073 0.2773
Brugia malayi nuclear receptor NHR-67 0.0019 0.0006 0.0006
Plasmodium vivax SET domain protein, putative 0.0033 0.0027 0.0296
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0224 0.0314 0.0314
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0004 0.0022
Echinococcus granulosus Niemann Pick C1 protein 0.0315 0.0451 0.0451
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0142 0.019 0.019
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0037 0.0032 0.0367
Trichomonas vaginalis glucosylceramidase, putative 0.0579 0.0848 0.5075
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0038 0.0038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0044 0.0044
Brugia malayi CHE-14 protein 0.0095 0.0119 0.0119
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0038 0.0038
Echinococcus granulosus dnaJ subfamily B 0.0472 0.0688 0.0688
Brugia malayi conserved hypotetical protein 0.0019 0.0006 0.0006
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0014 0.0424
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0038 0.0038
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0051 0.0051
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0019 0.0005 0.0014
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0044 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.1125 0.167 0.167
Loa Loa (eye worm) hypothetical protein 0.0056 0.0061 0.0061
Schistosoma mansoni kinase 0.0047 0.0048 0.0048
Echinococcus multilocularis chromobox protein 1 0.0076 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0147 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0027 0.0027
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.002 0.0006 0.0006
Brugia malayi ThiF family protein 0.0031 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0038
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0005 0.0014
Schistosoma mansoni inositol monophosphatase 0.0073 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0094 0.0118 0.0118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0032 0.0557
Schistosoma mansoni single-minded 0.0048 0.0049 0.0049
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0029 0.0502
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0015 0.0121
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0072 0.0084 0.0084
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0006 0.0006
Echinococcus multilocularis neuropeptide receptor A26 0.0473 0.0688 0.0688
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0006 0.0006
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0014 0.0206
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.1125 0.167 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0006 0.0006
Schistosoma mansoni cpg binding protein 0.0035 0.0029 0.0029
Loa Loa (eye worm) TYRA-2 protein 0.002 0.0006 0.0006
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0006 0.0006
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0578 0.0846 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0006 0.0006
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0031 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni patched 1 0.0095 0.0119 0.0119
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0005 0.0044
Loa Loa (eye worm) hypothetical protein 0.0033 0.0027 0.0027
Schistosoma mansoni tsg101-related 0.0057 0.0062 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Echinococcus multilocularis acetylcholinesterase 0.6658 1 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0037 0.0032 0.0367
Echinococcus granulosus lamin dm0 0.0027 0.0017 0.0017
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.002 0.0006 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0038 0.0038
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0004 0.0004
Brugia malayi G-protein coupled receptor 0.002 0.0006 0.0006
Echinococcus granulosus thyrotropin releasing hormone receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.004 0.0209
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0044 0.0044
Loa Loa (eye worm) cytochrome P450 0.0017 0.0003 0.0003
Toxoplasma gondii hypothetical protein 0.0047 0.0048 0.1787
Treponema pallidum fructose-bisphosphate aldolase 0.0578 0.0846 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.002 0.0006 0.0006
Brugia malayi hypothetical protein 0.0016 0.0001 0.0001
Onchocerca volvulus 0.002 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0006 0.0006
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.002 0.0006 0.0006
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0037 0.0032 0.0557
Onchocerca volvulus 0.1125 0.167 1
Onchocerca volvulus 0.0027 0.0017 0.0066
Trichomonas vaginalis ferritin, putative 0.0019 0.0005 0.0028
Schistosoma mansoni nuclear receptor 0.0019 0.0006 0.0006
Onchocerca volvulus 0.002 0.0006 0.0002
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0282 0.0401 0.239
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0015 0.0088
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0343 0.0492 0.579
Brugia malayi hypothetical protein 0.0025 0.0014 0.0014
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0015 0.0075
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0006 0.0006
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0579 0.0848 0.0848
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0045 0.0239
Echinococcus multilocularis BC026374 protein (S09 family) 0.1125 0.167 0.167
Schistosoma mansoni hypothetical protein 0.0051 0.0054 0.0054
Plasmodium falciparum flap endonuclease 1 0.0026 0.0015 0.0147
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.1125 0.167 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.002 0.0006 0.0006
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0039 0.0217
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0005 0.0028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0032 0.0557
Brugia malayi beta-lactamase family protein 0.0042 0.0039 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0038 0.0038
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0047 0.0048 0.0048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0038 0.0038
Brugia malayi hypothetical protein 0.0467 0.068 0.068
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0139 0.0185 0.0185
Schistosoma mansoni apoferritin-2 0.0019 0.0005 0.0005
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.002 0.0006 0.0006
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0006 0.0006
Brugia malayi Carboxylesterase family protein 0.1125 0.167 0.167
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0039 0.0698
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0036
Leishmania major cytochrome p450-like protein 0.0035 0.0029 0.0502
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.002 0.0006 0.0006
Echinococcus granulosus g protein coupled receptor 0.002 0.0006 0.0006
Schistosoma mansoni amine GPCR 0.002 0.0006 0.0006
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0027 0.0933
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0015 0.0119
Brugia malayi hypothetical protein 0.0022 0.0009 0.0009
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0037 0.0032 0.0557
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0006 0.0006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0027 0.0027
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0363 0.0523 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0045 0.0045
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0001 0.0005
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0039 0.0217
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0094 0.0118 0.0673
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.0117 0.0117
Echinococcus multilocularis protein dispatched 1 0.0108 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0156 0.0211 0.3997
Brugia malayi cytochrome P450 0.0017 0.0003 0.0003
Brugia malayi neuropeptide F receptor 0.002 0.0006 0.0006
Giardia lamblia DNA repair protein RAD52 0.0343 0.0492 0.579
Echinococcus granulosus sterol regulatory element binding protein 0.0095 0.0119 0.0119
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0084 0.0104 0.0588
Brugia malayi RNA binding protein 0.0142 0.019 0.019
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis Niemann Pick C1 protein 0.0315 0.0451 0.0451
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0069 0.008 0.008
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0038 0.0038
Mycobacterium tuberculosis Conserved protein 0.0042 0.0039 0.0217
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.002 0.0006 0.0006
Echinococcus granulosus neuroligin 0.1125 0.167 0.167
Schistosoma mansoni amine GPCR 0.002 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0097 0.0123 0.1404
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0027 0.0017 0.0017
Schistosoma mansoni opsin-like receptor 0.002 0.0006 0.0006
Brugia malayi nuclear receptor RXR 0.0022 0.0009 0.0009
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0005 0.0005
Schistosoma mansoni intermediate filament proteins 0.0027 0.0017 0.0017
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.002 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0006 0.0006
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0005 0.0005
Brugia malayi putative neuropeptide receptor 0.002 0.0006 0.0006
Echinococcus granulosus intermediate filament protein 0.0027 0.0017 0.0017
Brugia malayi nuclear hormone receptor 0.0041 0.0038 0.0038
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0015 0.0075
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1125 0.167 0.167
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0038 0.0038
Schistosoma mansoni growth hormone secretagogue receptor 0.002 0.0006 0.0006
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0039 0.0698
Onchocerca volvulus 0.002 0.0006 0.0002
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0032 0.0557
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0006 0.0006
Echinococcus granulosus acetylcholinesterase 0.6658 1 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.008 0.008
Echinococcus multilocularis sex peptide receptor 0.002 0.0006 0.0006
Schistosoma mansoni neuropeptide f receptor 76f 0.002 0.0006 0.0006
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0038 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.04 0.0579 0.3465
Brugia malayi chromobox protein homolog 3 0.0042 0.004 0.004
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0031 0.0024 0.0398
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.002 0.0006 0.0006
Trichomonas vaginalis glutathione reductase, putative 0.0037 0.0032 0.0188
Echinococcus granulosus fmrfamide receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0474 0.069 0.069
Echinococcus multilocularis fmrfamide receptor 0.002 0.0006 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0117 0.0696
Brugia malayi follicle stimulating hormone receptor 0.0474 0.069 0.069
Echinococcus granulosus G protein coupled receptor 139 0.002 0.0006 0.0006
Echinococcus multilocularis g protein coupled receptor 0.002 0.0006 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0039 0.0463
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0031 0.0024 0.0398
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0282 0.0401 0.239
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Onchocerca volvulus 0.0042 0.0039 0.0202
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0004 0.0006
Onchocerca volvulus 0.0046 0.0045 0.0238
Loa Loa (eye worm) melatonin receptor type 1A 0.002 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.038 0.0548 0.0548
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0015 0.0075
Echinococcus multilocularis dna polymerase eta 0.0019 0.0005 0.0005
Echinococcus multilocularis somatostatin receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0039 0.0232
Loa Loa (eye worm) hypothetical protein 0.0116 0.0151 0.0151
Brugia malayi Tachykinin-like peptides receptor 99D 0.002 0.0006 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0038 0.0038
Chlamydia trachomatis DNA gyrase subunit B 0.0081 0.0098 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.04 0.0579 0.3465
Plasmodium falciparum DNA topoisomerase 2 0.0139 0.0185 0.2388
Echinococcus multilocularis neuropeptide s receptor 0.0473 0.0688 0.0688
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Giardia lamblia NADH oxidase lateral transfer candidate 0.0037 0.0032 0.0317
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0579 0.0848 0.5075
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.038 0.0548 0.3281
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0038 0.0038
Brugia malayi ecdysteroid receptor 0.0041 0.0038 0.0038
Echinococcus granulosus survival motor neuron protein 1 0.0467 0.068 0.068
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.004 0.0239
Echinococcus multilocularis allatostatin A receptor 0.002 0.0006 0.0006
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0139 0.0185 0.0185
Onchocerca volvulus 0.002 0.0006 0.0002
Echinococcus granulosus dro:myosuppressin receptor 0.002 0.0006 0.0006
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0005 0.0005
Loa Loa (eye worm) carboxylesterase 0.6658 1 1
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0039 0.0217
Brugia malayi Cytochrome P450 family protein 0.0017 0.0003 0.0003
Schistosoma mansoni neuropeptide receptor 0.002 0.0006 0.0006
Schistosoma mansoni DNA topoisomerase type I 0.0185 0.0256 0.0256
Brugia malayi Niemann-Pick C1 protein precursor 0.0221 0.0309 0.0309
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0017
Plasmodium falciparum topoisomerase I 0.0185 0.0256 0.3316
Onchocerca volvulus 0.002 0.0006 0.0002
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0065 0.0075 0.0447
Echinococcus granulosus neuropeptide s receptor 0.0473 0.0688 0.0688
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0846 0.5066
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0015 0.0236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0006 0.0006
Trypanosoma brucei unspecified product 0.0019 0.0005 0.0044
Schistosoma mansoni BC026374 protein (S09 family) 0.1125 0.167 0.167
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0006 0.0006
Trichomonas vaginalis DNA topoisomerase II, putative 0.0139 0.0185 0.1106
Schistosoma mansoni amine GPCR 0.002 0.0006 0.0006
Echinococcus multilocularis para nitrobenzyl esterase 0.1125 0.167 0.167
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.0117 0.2189
Entamoeba histolytica hypothetical protein 0.0035 0.003 0.0294
Loa Loa (eye worm) hypothetical protein 0.0121 0.0158 0.0158
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0015 0.0236
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0044 0.0044
Plasmodium vivax glutathione reductase, putative 0.0106 0.0136 0.1741
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0049 0.0049
Echinococcus granulosus inositol monophosphatase 1 0.0073 0.0087 0.0087
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0031 0.0024 0.0258
Trichomonas vaginalis set domain proteins, putative 0.0258 0.0365 0.2183
Schistosoma mansoni ferritin 0.0019 0.0005 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.038 0.0548 0.3281
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0087 0.1608
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0006 0.0006
Onchocerca volvulus 0.002 0.0006 0.0002
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0065 0.0075 0.0447
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0363 0.0523 0.0523
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.1125 0.167 0.167
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0006 0.0006
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0006 0.0006
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0282 0.0401 0.9426
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis cpg binding protein 0.0035 0.0029 0.0029
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.0029 0.0156
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0009 0.0009
Schistosoma mansoni flap endonuclease-1 0.0023 0.0012 0.0012
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0027 0.0027
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0006 0.002
Leishmania major DNA topoisomerase IB, large subunit 0.0185 0.0256 0.486
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0073 0.0087 0.0966
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0037 0.0032 0.0367
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0006 0.0006
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.0117 0.1325
Loa Loa (eye worm) DNA topoisomerase I 0.0185 0.0256 0.0256
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0038 0.0038
Echinococcus granulosus BC026374 protein S09 family 0.1125 0.167 0.167
Echinococcus multilocularis ferritin 0.0019 0.0005 0.0005
Echinococcus granulosus peptide allatostatin:somatostatin 0.002 0.0006 0.0006
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0027 0.0027
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.002 0.0006 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0142 0.019 0.019
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0027 0.0017 0.0272
Schistosoma mansoni tar DNA-binding protein 0.0142 0.019 0.019
Trichomonas vaginalis glucosylceramidase, putative 0.038 0.0548 0.3281
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Onchocerca volvulus 0.1125 0.167 1
Mycobacterium ulcerans putative regulatory protein 0.0036 0.003 0.0164
Brugia malayi PAS domain containing protein 0.0048 0.0049 0.0049
Mycobacterium ulcerans bacterioferritin BfrB 0.0019 0.0005 0.0014
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0037 0.0032 0.0174
Schistosoma mansoni hypothetical protein 0.0091 0.0114 0.0114
Entamoeba histolytica hypothetical protein 0.0035 0.003 0.0294
Brugia malayi Dopamine receptor protein 2 0.002 0.0006 0.0006
Mycobacterium ulcerans DNA gyrase subunit B 0.0081 0.0098 0.0572
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0009
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0014 0.0126
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0038 0.0038
Brugia malayi DNA topoisomerase I 0.0185 0.0256 0.0256
Echinococcus multilocularis tar DNA binding protein 0.0142 0.019 0.019
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0269 0.0381 0.2268
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0579 0.0848 0.0848
Onchocerca volvulus 0.002 0.0006 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0006 0.0006
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0038 0.0195
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0069 0.008 0.008
Echinococcus multilocularis Niemann Pick C1 protein 0.0221 0.0309 0.0309
Chlamydia trachomatis DNA gyrase subunit B 0.0064 0.0073 0.7244
Echinococcus multilocularis survival motor neuron protein 1 0.0467 0.068 0.068
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0242 0.0341 0.7984
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0006 0.0006
Schistosoma mansoni amine GPCR 0.002 0.0006 0.0006
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0006 0.0006
Trypanosoma cruzi trypanothione reductase, putative 0.0106 0.0136 0.2562
Schistosoma mansoni survival motor neuron protein 0.0095 0.012 0.012
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0003 0.0003
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0047 0.0048 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0005 0.0044
Echinococcus granulosus geminin 0.038 0.0548 0.0548
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0015 0.0236
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Giardia lamblia Kinase, PLK 0.0093 0.0117 0.1325
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0015 0.0075
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0042 0.004 0.004
Echinococcus granulosus hypothetical protein 0.0699 0.103 0.103
Onchocerca volvulus 0.002 0.0006 0.0002
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0038 0.0038
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0006 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0032 0.0557
Loa Loa (eye worm) inositol-1 0.0073 0.0087 0.0087
Schistosoma mansoni adenoreceptor 0.002 0.0006 0.0006
Brugia malayi intermediate filament protein 0.0027 0.0017 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0044 0.0044
Schistosoma mansoni biogenic amine receptor 0.002 0.0006 0.0006
Brugia malayi hypothetical protein 0.0035 0.003 0.003
Brugia malayi ThiF family protein 0.0047 0.0048 0.0048
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0095 0.0119 0.0119
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0036
Mycobacterium tuberculosis Probable reductase 0.0242 0.0341 0.2025
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0037 0.0032 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0015 0.0075
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0006 0.0006
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0004 0.0022
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0004 0.0007
Echinococcus granulosus dna polymerase kappa 0.0019 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Brugia malayi Flap endonuclease-1 0.0026 0.0015 0.0015
Schistosoma mansoni microtubule-associated protein tau 0.1364 0.203 0.203
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0081 0.0098 0.2212
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis inositol monophosphatase 1 0.0073 0.0087 0.0087
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0015 0.0015
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.1125 0.167 0.167
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0038
Schistosoma mansoni neuroligin 3 (S09 family) 0.1125 0.167 0.167
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0044 0.0044
Leishmania major DNA topoisomerase ii 0.0131 0.0174 0.329
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0094 0.0118 0.0673
Echinococcus granulosus expressed conserved protein 0.0207 0.0289 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0117 0.0696
Echinococcus granulosus chromobox protein 1 0.0076 0.0091 0.0091
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0037 0.0032 0.0557
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0038 0.0038
Echinococcus granulosus tachykinin peptides receptor 99D 0.002 0.0006 0.0006
Brugia malayi RE15519p 0.002 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0579 0.0848 0.5075
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0014 0.0206
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0038 0.0038
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.002 0.0006 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0038 0.0038
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0087 0.1608
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0038 0.0038
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Brugia malayi Carboxylesterase family protein 0.1125 0.167 0.167
Schistosoma mansoni biogenic amine receptor 0.002 0.0006 0.0006
Brugia malayi Carboxylesterase family protein 0.1125 0.167 0.167
Onchocerca volvulus 0.002 0.0006 0.0002
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0015 0.0121
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.003 0.0021 0.0733
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0039 0.0698
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0036 0.0031 0.0659
Trichomonas vaginalis glutaminase, putative 0.0267 0.0378 0.2264
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0022 0.001 0.0128
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Schistosoma mansoni biogenic amine receptor 0.002 0.0006 0.0006
Trypanosoma brucei telomerase reverse transcriptase 0.0084 0.0104 0.1935
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0039 0.0217
Echinococcus granulosus dna polymerase eta 0.0019 0.0005 0.0005
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0006 0.0006
Leishmania major ubiquitin-activating enzyme-like protein 0.0031 0.0024 0.0398
Brugia malayi steroid hormone receptor 0.0041 0.0038 0.0038
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0005 0.0005
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0117 0.2189
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0027 0.0027
Loa Loa (eye worm) TAR-binding protein 0.0142 0.019 0.019
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Brugia malayi beta-lactamase 0.0042 0.0039 0.0039
Echinococcus multilocularis expressed protein 0.0019 0.0005 0.0005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0006 0.0006
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0106 0.0136 0.0799
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0006 0.0006
Brugia malayi GnHR receptor homolog 0.002 0.0006 0.0006
Echinococcus multilocularis tachykinin peptides receptor 99D 0.002 0.0006 0.0006
Plasmodium falciparum glutathione reductase 0.0106 0.0136 0.1741
Leishmania major hypothetical protein, conserved 0.0042 0.0039 0.0698
Schistosoma mansoni DNA polymerase eta 0.0019 0.0005 0.0005
Schistosoma mansoni inositol monophosphatase 0.0073 0.0087 0.0087
Brugia malayi Pre-SET motif family protein 0.0033 0.0027 0.0027
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0004 0.0045
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni glutaminase 0.0267 0.0378 0.0378
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0047 0.0048 0.0048
Loa Loa (eye worm) hypoxia-induced factor 1 0.0149 0.0201 0.0201
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0578 0.0846 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0038 0.0038
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0038 0.0038
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.0117 0.0117
Loa Loa (eye worm) thioredoxin reductase 0.0106 0.0136 0.0136
Leishmania major C-8 sterol isomerase-like protein 0.0363 0.0523 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0269 0.0381 0.2268
Echinococcus granulosus para nitrobenzyl esterase 0.1125 0.167 0.167
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0015 0.0239
Echinococcus granulosus cpg binding protein 0.0035 0.0029 0.0029
Brugia malayi glutaminase DH11.1 0.0267 0.0378 0.0378
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis fmrfamide receptor 0.002 0.0006 0.0006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1125 0.167 0.167
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0065 0.0075 0.0432
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.0117 0.0117
Echinococcus multilocularis biogenic amine (5HT) receptor 0.002 0.0006 0.0006
Onchocerca volvulus 0.0026 0.0015 0.0059
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0038 0.0038
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0009 0.0009
Leishmania major telomerase reverse transcriptase, putative 0.0084 0.0104 0.1935
Echinococcus granulosus family S9 non peptidase ue S09 family 0.1125 0.167 0.167
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0039 0.0217
Schistosoma mansoni cytochrome P450 0.0017 0.0003 0.0003
Chlamydia trachomatis DNA gyrase subunit A 0.003 0.0021 0.1716
Brugia malayi hypothetical protein 0.0019 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0027 0.0027
Onchocerca volvulus 0.0041 0.0038 0.0195
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0024 0.0024
Trichomonas vaginalis spcc417.12 protein, putative 0.1125 0.167 1
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0046 0.0272
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0038
Brugia malayi Serotonin receptor 0.002 0.0006 0.0006
Echinococcus multilocularis protein patched 0.0095 0.0119 0.0119
Trichomonas vaginalis glucosylceramidase, putative 0.038 0.0548 0.3281
Trypanosoma cruzi hypothetical protein 0.0065 0.0075 0.1388
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.002 0.0006 0.0006
Echinococcus multilocularis lamin 0.0027 0.0017 0.0017
Trypanosoma brucei DNA topoisomerase ii 0.0156 0.0211 0.3997
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0009
Echinococcus granulosus serotonin receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0094 0.0118 0.0118
Schistosoma mansoni coup transcription factor 0.0041 0.0038 0.0038
Schistosoma mansoni DNA topoisomerase type I 0.0185 0.0256 0.0256
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0031 0.0024 0.0024
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0015 0.0239
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0015 0.0015
Schistosoma mansoni amine GPCR 0.002 0.0006 0.0006
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0227 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0037 0.0032 0.0367
Loa Loa (eye worm) hypothetical protein 0.0185 0.0256 0.0256
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.003 0.003
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0039 0.0217
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0037 0.0032 0.0634
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0038 0.0038
Brugia malayi hypothetical protein 0.1125 0.167 0.167
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0038 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0038 0.0038
Leishmania major DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Echinococcus granulosus sentrin specific protease 8 0.0065 0.0075 0.0075
Echinococcus granulosus Protein patched homolog 1 0.0095 0.0119 0.0119
Brugia malayi Serotonin/octopamine receptor family protein 7 0.002 0.0006 0.0006
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.6658 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0014 0.0126
Loa Loa (eye worm) beta-lactamase 0.0042 0.0039 0.0039
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0579 0.0848 0.5075
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0016
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0051 0.0051
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0037 0.0032 0.0557
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0022 0.001 0.0128
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0029 0.0029
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0047 0.0048 0.0581
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.002 0.0006 0.0006
Onchocerca volvulus 0.1125 0.167 1
Brugia malayi larval opioid receptor 0.002 0.0006 0.0006
Echinococcus multilocularis G-protein coupled receptor, putative 0.002 0.0006 0.0006
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0037 0.0032 0.0032
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0015 0.0015
Echinococcus granulosus orexin receptor type 2 0.002 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0035 0.003 0.003
Loa Loa (eye worm) TOPoisomerase family member 0.0139 0.0185 0.0185
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0846 0.5066
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0037 0.0032 0.0557
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0006 0.0006
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0065 0.0075 0.0447
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.002 0.0006 0.0006
Schistosoma mansoni chromobox protein 0.0076 0.0091 0.0091
Schistosoma mansoni neuropeptide receptor 0.002 0.0006 0.0006
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0065 0.0075 0.0075
Echinococcus multilocularis neuropeptide receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0298 0.0426 1
Echinococcus granulosus single minded 2 0.0036 0.003 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0038 0.0038
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0044
Loa Loa (eye worm) hypothetical protein 0.1125 0.167 0.167
Trypanosoma brucei trypanothione reductase 0.0106 0.0136 0.2562
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0005 0.0005
Schistosoma mansoni myosin xvIII 0.002 0.0006 0.0006
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Brugia malayi bHLH-PAS transcription factor 0.0036 0.003 0.003
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0117 0.2189
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0014 0.0126
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0004 0.0022
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0005 0.0028
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0006 0.0006
Loa Loa (eye worm) glutathione reductase 0.0106 0.0136 0.0136
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0036
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0027 0.0017 0.0017
Echinococcus granulosus neuropeptide FF receptor 2 0.002 0.0006 0.0006
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0095 0.0119 0.0119
Mycobacterium leprae Probable lipase LipE 0.0042 0.0039 0.0858
Echinococcus multilocularis lamin dm0 0.0027 0.0017 0.0017
Brugia malayi sulfakinin receptor protein 0.002 0.0006 0.0006
Loa Loa (eye worm) heterochromatin protein 1 0.0076 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0056 0.0061 0.0061
Leishmania major DNA polymerase eta, putative 0.0019 0.0005 0.0044
Echinococcus multilocularis DNA topoisomerase 1 0.0185 0.0256 0.0256
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni lamin 0.0027 0.0017 0.0017
Loa Loa (eye worm) carboxylesterase 0.1125 0.167 0.167
Brugia malayi beta-lactamase family protein 0.0042 0.0039 0.0039
Schistosoma mansoni zinc finger protein 0.0019 0.0006 0.0006
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0185 0.0256 0.486
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.038 0.0548 0.3281
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0015 0.0015
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0038 0.0038
Echinococcus granulosus 7TM GPCR rhodopsin 0.002 0.0006 0.0006
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0039 0.0217
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0007 0.0036
Schistosoma mansoni DNA topoisomerase II 0.0139 0.0185 0.0185
Brugia malayi Carboxylesterase family protein 0.1125 0.167 0.167
Brugia malayi Pre-SET motif family protein 0.0227 0.0318 0.0318
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0038 0.0038
Brugia malayi ORL1-like opioid receptor 0.002 0.0006 0.0006
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0006 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0044
Toxoplasma gondii DNA topoisomerase 2, putative 0.0139 0.0185 0.7214
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0091 0.0114 0.0114
Schistosoma mansoni tar DNA-binding protein 0.0142 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0081 0.0098 0.0572
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0015 0.0294
Schistosoma mansoni peptide (allatostatin)-like receptor 0.002 0.0006 0.0006
Schistosoma mansoni opsin-like receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.002 0.0006 0.0006
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0029 0.0502
Plasmodium falciparum thioredoxin reductase 0.0037 0.0032 0.0367
Echinococcus multilocularis acetylcholinesterase 0.6658 1 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.002 0.0006 0.0006
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0039 0.0039
Onchocerca volvulus 0.0042 0.0039 0.0202
Toxoplasma gondii RNA-directed DNA polymerase 0.0084 0.0104 0.3981
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0846 0.5066
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0038 0.0195
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0269 0.0381 0.8945
Brugia malayi isocitrate dehydrogenase 0.0018 0.0004 0.0004
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0156 0.0211 0.3997
Loa Loa (eye worm) hypothetical protein 0.0121 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.003 0.003
Brugia malayi Cytochrome P450 family protein 0.0035 0.0029 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.038 0.0548 0.3281
Trypanosoma cruzi DNA topoisomerase II, putative 0.0131 0.0174 0.329
Toxoplasma gondii ThiF family protein 0.0031 0.0024 0.082
Brugia malayi G protein-coupled receptor F59B2.13 0.002 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0472 0.0688 0.0688
Schistosoma mansoni hypothetical protein 0.0091 0.0114 0.0114
Mycobacterium ulcerans lipase LipD 0.0042 0.0039 0.0217
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.003 0.003
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0006 0.0006
Plasmodium falciparum telomerase reverse transcriptase 0.0522 0.0763 1
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0006 0.0006
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0047 0.0047 0.0494
Echinococcus multilocularis g protein coupled receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0009
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0033 0.0027 0.0027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0032 0.0557
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.6658 1 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0006 0.0006
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0139 0.0185 0.0185
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0037 0.0032 0.0557
Onchocerca volvulus 0.002 0.0006 0.0002
Mycobacterium ulcerans hypothetical protein 0.0026 0.0015 0.0075
Treponema pallidum cell division protein FtsZ 0.0298 0.0426 0.5
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0039 0.0232
Brugia malayi Heterochromatin protein 1 0.0076 0.0091 0.0091
Onchocerca volvulus 0.002 0.0006 0.0002
Giardia lamblia Fructose-bisphosphate aldolase 0.0578 0.0846 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0037 0.0032 0.0557
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0044
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0009 0.0009
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0051 0.0051
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0037 0.0032 0.284
Brugia malayi putative neuropeptide receptor NPR1 0.002 0.0006 0.0006
Echinococcus multilocularis chromobox protein 1 0.0076 0.0091 0.0091
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0039 0.0858
Leishmania major trypanothione reductase 0.0106 0.0136 0.2562
Mycobacterium ulcerans bacterioferritin BfrA 0.0019 0.0005 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0044
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0006 0.002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0038 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0846 0.5066
Mycobacterium tuberculosis Conserved protein 0.0042 0.0039 0.0217
Mycobacterium ulcerans glutaminase 0.0267 0.0378 0.2252
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0015 0.0075
Schistosoma mansoni acetylcholinesterase 0.1125 0.167 0.167
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0038 0.0038
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0038 0.0038
Echinococcus granulosus muscleblind protein 0.0147 0.0198 0.0198
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0003 0.0003
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0038 0.0038
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.1125 0.167 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Brugia malayi tailless protein 0.0019 0.0006 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0015 0.0239
Treponema pallidum NADH oxidase 0.0037 0.0032 0.0317
Leishmania major hypothetical protein, conserved 0.0022 0.001 0.0128
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0081 0.0098 0.3772
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0242 0.0341 0.2025
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0009 0.0009
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0073 0.0087 0.1933
Brugia malayi Serotonin receptor 0.002 0.0006 0.0006
Trichomonas vaginalis inositol monophosphatase, putative 0.0073 0.0087 0.0515
Brugia malayi nuclear receptor RXR 0.0019 0.0006 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Entamoeba histolytica hypothetical protein 0.0035 0.003 0.0294
Toxoplasma gondii ABC1 family protein 0.0042 0.0039 0.1435
Brugia malayi Carboxylesterase family protein 0.6658 1 1
Brugia malayi Probable DNA topoisomerase II 0.0139 0.0185 0.0185
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0037 0.0032 0.0174
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.012 0.012
Schistosoma mansoni lamin 0.0027 0.0017 0.0017
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0081 0.0098 0.1106
Mycobacterium ulcerans DNA gyrase subunit A 0.003 0.0021 0.0111
Trypanosoma brucei C-8 sterol isomerase, putative 0.0363 0.0523 1
Mycobacterium leprae cell division protein FtsZ 0.0298 0.0426 1
Loa Loa (eye worm) Ulp1 protease 0.0065 0.0075 0.0075
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0006 0.0006
Mycobacterium ulcerans hypothetical protein 0.0042 0.0039 0.0217
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.038 0.0548 0.0548
Plasmodium vivax topoisomerase I, putative 0.0185 0.0256 0.3316
Echinococcus multilocularis serotonin receptor 0.002 0.0006 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0006 0.0006
Echinococcus multilocularis carboxylesterase 5A 0.6658 1 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0038 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0006 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0846 0.5066
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.002 0.0006 0.0006
Toxoplasma gondii DNA topoisomerase I, putative 0.0185 0.0256 1
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0038 0.0038
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0004 0.0004
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0185 0.0256 0.486
Onchocerca volvulus 0.1125 0.167 1
Schistosoma mansoni tar DNA-binding protein 0.0142 0.019 0.019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0846 0.5066
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.6658 1 1
Schistosoma mansoni tar DNA-binding protein 0.0142 0.019 0.019
Brugia malayi G-protein coupled receptor 0.002 0.0006 0.0006
Echinococcus granulosus microtubule associated protein 2 0.1364 0.203 0.203
Schistosoma mansoni ferritin light chain 0.0019 0.0005 0.0005
Brugia malayi Cell division protein ftsZ 0.0147 0.0198 0.0198
Giardia lamblia Telomerase catalytic subunit 0.0084 0.0104 0.1169
Echinococcus multilocularis serotonin receptor 0.002 0.0006 0.0006
Leishmania major mitochondrial DNA topoisomerase II 0.0156 0.0211 0.3997
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0038 0.0038
Brugia malayi hypothetical protein 0.0162 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0038
Trichomonas vaginalis hypothetical protein 0.0033 0.0027 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.004 0.0239
Onchocerca volvulus Huntingtin homolog 0.0121 0.0158 0.0917
Echinococcus granulosus alpha 1A adrenergic receptor 0.002 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0579 0.0848 0.5075
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0014 0.0206
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0269 0.0381 0.2268
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0087 0.0515
Onchocerca volvulus Neuropeptide F receptor homolog 0.002 0.0006 0.0002
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0004 0.0022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0004 0.0006
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.003 0.0021 0.0111
Brugia malayi hypothetical protein 0.0069 0.008 0.008
Schistosoma mansoni tsg101-related 0.0047 0.0047 0.0047
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0006 0.0006
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0094 0.0118 0.0673
Loa Loa (eye worm) CYP4Cod1 0.0035 0.0029 0.0029
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0037 0.0032 0.0174
Trichomonas vaginalis glucosylceramidase, putative 0.0579 0.0848 0.5075
Schistosoma mansoni opsin-like receptor 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.1125 0.167 0.167
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0006 0.0006
Echinococcus granulosus neuropeptide receptor A26 0.0473 0.0688 0.0688
Brugia malayi Dopamine receptor 0.002 0.0006 0.0006
Echinococcus granulosus neuropeptide receptor 0.002 0.0006 0.0006
Trypanosoma brucei polo-like protein kinase 0.0093 0.0117 0.2189
Echinococcus multilocularis dnaJ subfamily B 0.0472 0.0688 0.0688
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0087 0.1608
Echinococcus granulosus thioredoxin glutathione reductase 0.0106 0.0136 0.0136
Loa Loa (eye worm) ThiF family protein 0.0031 0.0024 0.0024
Giardia lamblia DNA topoisomerase II 0.0131 0.0174 0.2011
Schistosoma mansoni alpha-1 adrenergic receptor 0.002 0.0006 0.0006
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0039 0.0232
Plasmodium falciparum DNA gyrase subunit A 0.003 0.0021 0.0229
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Onchocerca volvulus 0.002 0.0006 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0221 0.0309 0.0309
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0846 0.5066
Echinococcus granulosus flap endonuclease 1 0.0026 0.0015 0.0015
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0044 0.0044
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0006 0.0006
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0038 0.0038
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0073 0.0087 0.0501
Schistosoma mansoni hypothetical protein 0.0091 0.0114 0.0114
Onchocerca volvulus 0.0258 0.0365 0.2159
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0022 0.0128
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0017 0.0017
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0038 0.0038
Echinococcus granulosus ferritin 0.0019 0.0005 0.0005
Echinococcus multilocularis microtubule associated protein 2 0.1364 0.203 0.203
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0045 0.0268
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0117 0.0696
Onchocerca volvulus 0.002 0.0006 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0022 0.0128
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.003 0.0021 0.0193
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0006 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0117 0.0696
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0084 0.0104 0.1935
Echinococcus multilocularis neuroligin 0.1125 0.167 0.167
Entamoeba histolytica DNA topoisomerase II, putative 0.0139 0.0185 0.214
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trypanosoma brucei cytochrome P450, putative 0.0035 0.0029 0.0502
Chlamydia trachomatis DNA gyrase subunit A 0.003 0.0021 0.1716
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0006 0.0006
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0037 0.0032 0.0557
Plasmodium falciparum glutathione reductase 0.0037 0.0032 0.0367
Echinococcus multilocularis muscleblind protein 1 0.0147 0.0198 0.0198
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0131 0.0174 0.329
Schistosoma mansoni cpg binding protein 0.0033 0.0027 0.0027
Schistosoma mansoni histamine h1 receptor 0.002 0.0006 0.0006
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0039 0.0217
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0015 0.0075
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0015 0.0075
Echinococcus multilocularis sentrin specific protease 8 0.0065 0.0075 0.0075
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0038 0.0038
Mycobacterium tuberculosis Cell division protein FtsZ 0.0298 0.0426 0.2536
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0004 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0006 0.0006
Echinococcus multilocularis G protein coupled receptor 139 0.002 0.0006 0.0006
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0004 0.0004
Onchocerca volvulus 0.002 0.0006 0.0002

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 30 uM Inhibition of p-ERK level in human COLO205 cells after 75 mins by crystal violet staining ChEMBL. 19097792

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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