Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | fructose-bisphospatase II | 0.1055 | 1 | 1 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.1055 | 1 | 1 |
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.0392 | 0.3631 | 0.3631 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0015 | 0 | 0.5 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.1055 | 1 | 1 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0392 | 0.3631 | 0.3631 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.1055 | 1 | 1 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.1055 | 1 | 1 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0392 | 0.3631 | 0.3631 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.1055 | 1 | 0.5 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.1055 | 1 | 0.5 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.1055 | 1 | 0.5 |
Leishmania major | 0.1055 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.