Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.1448 | 0.1128 | 1 |
Schistosoma mansoni | GMP synthetase | 0.0032 | 0.0016 | 0.0016 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0072 | 0.0048 | 0.0048 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.0173 | 0.1536 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.1448 | 0.1128 | 0.1408 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0012 | 0.0001 | 0.0001 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.0045 | 0.0045 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0021 | 0.0008 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0000096463 | 0.0000093957 |
Echinococcus multilocularis | geminin | 0.0166 | 0.0121 | 0.0121 |
Onchocerca volvulus | 0.004 | 0.0023 | 0.0096 | |
Onchocerca volvulus | Putative hydroxypyruvate isomerase | 0.002 | 0.0007 | 0.0028 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 1.2749 | 1 | 1 |
Trichomonas vaginalis | nh(3)-dependent NAD(+) synthetase, putative | 0.008 | 0.0054 | 0.0482 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Echinococcus multilocularis | thymidylate synthase | 0.3044 | 0.2381 | 0.2381 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0014 | 0.0014 |
Brugia malayi | Uncoordinated protein 44 | 0.0014 | 0.0002 | 0.0002 |
Brugia malayi | Pre-SET motif family protein | 0.0204 | 0.0151 | 0.0151 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0014 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.3044 | 0.2381 | 1 | |
Leishmania major | GMP synthase, putative,glutamine amidotransferase, putative | 0.0032 | 0.0016 | 0.0021 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0001 | 0.0001 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0014 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0059 | 0.0037 | 0.0035 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0059 | 0.0037 | 0.0047 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0001 | 0.0001 |
Plasmodium falciparum | glutamine-dependent NAD(+) synthetase, putative | 0.008 | 0.0054 | 0.0068 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Entamoeba histolytica | NAD synthetase, putative | 0.008 | 0.0054 | 1 |
Onchocerca volvulus | 0.0014 | 0.0003 | 0.0011 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0012 | 0.0111 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.0121 | 0.0121 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0021 | 0.0021 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000025061 | 0.0000022213 |
Echinococcus multilocularis | Chromo domain | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0021 | 0.0021 |
Giardia lamblia | NH3-dependent NAD+ synthetase | 0.008 | 0.0054 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0014 | 0.0014 |
Mycobacterium ulcerans | epimerase | 0.002 | 0.0007 | 0.0006 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0014 | 0.0014 |
Leishmania major | oxidoreductase-like protein | 0.0014 | 0.0003 | 0.0003 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0024 | 0.0209 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Brugia malayi | Dihydrofolate reductase | 1.2749 | 1 | 1 |
Brugia malayi | Death domain containing protein | 0.0014 | 0.0002 | 0.0002 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0000096463 | 0.0000093957 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 1.0215 | 0.8011 | 1 |
Mycobacterium ulcerans | NAD synthetase | 0.008 | 0.0054 | 0.0054 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0014 | 0.0014 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0014 | 0.0002 | 0.0003 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0014 | 0.0003 | 0.0002 |
Brugia malayi | GMP synthase | 0.0032 | 0.0016 | 0.0016 |
Trichomonas vaginalis | hypothetical protein | 0.0011 | 0.00000025061 | 0.0000022213 |
Echinococcus granulosus | thymidylate synthase | 0.3044 | 0.2381 | 0.2381 |
Echinococcus granulosus | GMP synthase glutamine hydrolyzing | 0.0032 | 0.0016 | 0.0016 |
Mycobacterium tuberculosis | Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) | 0.008 | 0.0054 | 0.0052 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0001 | 0.0001 |
Plasmodium vivax | apurinic/apyrimidinic endonuclease Apn1, putative | 0.0075 | 0.005 | 0.0063 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0059 | 0.0037 | 0.0037 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0021 | 0.0008 | 0.0068 |
Trypanosoma cruzi | NAD+ synthase, putative | 0.008 | 0.0054 | 0.0068 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000025061 | 0.0000022213 |
Schistosoma mansoni | glutamine-dependent NAD(+) synthetase | 0.008 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0007 | 0.0007 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.004 | 0.0023 | 0.0023 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.0045 | 0.0045 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0002 | 0.0002 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0059 | 0.0037 | 0.0037 |
Echinococcus granulosus | bloom syndrome protein | 0.0021 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Hypothetical protein | 0.1448 | 0.1128 | 0.1126 |
Mycobacterium ulcerans | GMP synthase | 0.0032 | 0.0016 | 0.0016 |
Trypanosoma cruzi | NAD+ synthase, putative | 0.008 | 0.0054 | 0.0068 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.0045 | 0.0045 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0014 | 0.0002 | 0.0002 |
Echinococcus granulosus | Chromobox protein 3 | 0.0011 | 0.00000025221 | 0.0000000016019 |
Plasmodium vivax | glutamine-dependent NAD(+) synthetase, putative | 0.008 | 0.0054 | 0.0068 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0014 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | sugar phosphate isomerases/epimerases | 0.002 | 0.0007 | 0.0006 |
Toxoplasma gondii | bifunctional GMP synthase/glutamine amidotransferase protein | 0.0032 | 0.0016 | 0.0021 |
Brugia malayi | Protein kinase domain containing protein | 0.0014 | 0.0002 | 0.0002 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 1.0215 | 0.8011 | 1 |
Trypanosoma brucei | pteridine reductase 1 | 0.019 | 0.0141 | 0.0176 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0014 | 0.0003 | 0.0002 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0072 | 0.0048 | 0.0048 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Mycobacterium leprae | PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) | 0.0075 | 0.005 | 0.0043 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.0121 | 0.0121 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.0045 | 0.0397 |
Brugia malayi | follicle stimulating hormone receptor | 0.0231 | 0.0173 | 0.0173 |
Brugia malayi | SET domain containing protein | 0.0012 | 0.0001 | 0.0001 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.0045 | 0.0397 |
Loa Loa (eye worm) | RecQ helicase | 0.0021 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.3044 | 0.2381 | 0.2379 |
Chlamydia trachomatis | dihydrofolate reductase | 1.2749 | 1 | 1 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0014 | 0.0003 | 0.0003 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.0045 | 0.0045 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.0045 | 0.0045 |
Schistosoma mansoni | dihydrofolate reductase | 1.2749 | 1 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0014 | 0.0002 | 0.0003 |
Plasmodium falciparum | chromodomain-helicase-DNA-binding protein 1 homolog, putative | 0.0011 | 0.00000025061 | 0.0000000000034853 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0014 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0016 | 0.0016 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.00000025061 | 0.0000022213 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0014 | 0.0003 | 0.0002 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.3044 | 0.2381 | 0.2381 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0018 | 0.0006 | 0.0007 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Schistosoma mansoni | netrin receptor unc5 | 0.0014 | 0.0002 | 0.0002 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Trypanosoma brucei | GMP synthase [glutamine-hydrolysing] | 0.0032 | 0.0016 | 0.0021 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0021 | 0.0089 |
Plasmodium vivax | GMP synthetase, putative | 0.0032 | 0.0016 | 0.0021 |
Echinococcus granulosus | Chromo domain | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Brugia malayi | DNA-(Apurinic or apyrimidinic site) lyase | 0.0075 | 0.005 | 0.005 |
Echinococcus granulosus | dihydrofolate reductase | 1.2749 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0001 | 0.0001 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.3044 | 0.2381 | 0.2376 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0002 | 0.0002 |
Schistosoma mansoni | glutamine-dependent NAD(+) synthetase | 0.0048 | 0.0029 | 0.0029 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.00000025061 | 0.0000022213 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0015 | 0.0015 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 1.0215 | 0.8011 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000025061 | 0.0000022213 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Treponema pallidum | NAD synthetase | 0.008 | 0.0054 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0014 | 0.0002 | 0.0002 |
Brugia malayi | hypothetical protein | 0.1448 | 0.1128 | 0.1128 |
Onchocerca volvulus | 0.0232 | 0.0173 | 0.0728 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000025061 | 0.0000022213 |
Trypanosoma brucei | cytochrome P450, putative | 0.0012 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | endonuclease IV | 0.0075 | 0.005 | 0.0049 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0014 | 0.0002 | 0.0002 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0014 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) | 0.0075 | 0.005 | 0.0048 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000025061 | 0.0000022213 |
Onchocerca volvulus | 0.0011 | 0.00000025221 | 0.0000000067276 | |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0007 | 0.0004 |
Brugia malayi | thymidylate synthase | 0.3044 | 0.2381 | 0.2381 |
Onchocerca volvulus | 0.003 | 0.0015 | 0.0062 | |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 1.2749 | 1 | 1 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 1.0215 | 0.8011 | 1 |
Echinococcus granulosus | geminin | 0.0166 | 0.0121 | 0.0121 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0024 | 0.0209 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0024 | 0.0099 |
Plasmodium falciparum | apurinic/apyrimidinic endonuclease Apn1, putative | 0.0075 | 0.005 | 0.0063 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0014 | 0.0002 | 0.0002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000025061 | 0.0000022213 |
Plasmodium vivax | hypothetical protein, conserved | 0.0011 | 0.00000025061 | 0.0000000000034853 |
Mycobacterium ulcerans | hypothetical protein | 0.002 | 0.0007 | 0.0006 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0016 | 0.0004 | 0.0004 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0021 | 0.0008 | 0.0008 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0021 | 0.0188 |
Leishmania major | NAD synthase, putative | 0.008 | 0.0054 | 0.0068 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | dihydrofolate reductase | 1.2749 | 1 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0014 | 0.0018 |
Plasmodium falciparum | GMP synthase [glutamine-hydrolyzing] | 0.0032 | 0.0016 | 0.0021 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0001 | 0.0001 |
Echinococcus multilocularis | dihydrofolate reductase | 1.2749 | 1 | 1 |
Echinococcus multilocularis | GMP synthase (glutamine hydrolyzing) | 0.0032 | 0.0016 | 0.0016 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0014 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0231 | 0.0173 | 0.0173 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Echinococcus multilocularis | Ankyrin | 0.0014 | 0.0002 | 0.0002 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.00000025061 | 0.0000022213 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.005 | 0.005 |
Leishmania major | pteridine reductase 1 | 0.0197 | 0.0146 | 0.0182 |
Onchocerca volvulus | Netrin receptor homolog | 0.0014 | 0.0002 | 0.001 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0059 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0004 | 0.0004 |
Trypanosoma brucei | NAD+ synthase, putative | 0.008 | 0.0054 | 0.0068 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0059 | 0.0037 | 0.0037 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 1.0215 | 0.8011 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0014 | 0.0014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000025061 | 0.0000022213 |
Toxoplasma gondii | glutamine-dependent NAD(+) synthetase protein, putative | 0.008 | 0.0054 | 0.0068 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0012 | 0.0111 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0001 | 0.0001 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 1.2749 | 1 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0012 | 0.0001 | 0.0001 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0014 | 0.0018 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000025061 | 0.0000022213 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 1.0215 | 0.8011 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000025061 | 0.0000022213 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.0045 | 0.0045 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.00000025061 | 0.0000022214 |
Brugia malayi | CHD4 protein | 0.0011 | 0.00000025061 | 0.0000000000027919 |
Mycobacterium ulcerans | thymidylate synthase | 0.3044 | 0.2381 | 0.2381 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0204 | 0.0151 | 0.0151 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.0045 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0014 | 0.0014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0021 | 0.0188 |
Mycobacterium leprae | PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) | 0.008 | 0.0054 | 0.0048 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.0045 | 0.0045 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0014 | 0.0003 | 0.0002 |
Echinococcus multilocularis | bloom syndrome protein | 0.0021 | 0.0008 | 0.0008 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0011 | 0.00000025221 | 0.0000000016019 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0059 | 0.0037 | 0.0037 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0014 | 0.0014 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0059 | 0.0037 | 0.0037 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0014 | 0.0014 |
Echinococcus granulosus | Ankyrin | 0.0014 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | thymidylate synthase | 0.3044 | 0.2381 | 0.2381 |
Trichomonas vaginalis | Heterochromatin protein, putative | 0.0011 | 0.00000025061 | 0.0000022213 |
Toxoplasma gondii | endonuclease IV APN | 0.0075 | 0.005 | 0.0063 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0061 | 0.0039 | 0.0039 |
Brugia malayi | Hypothetical 29.7 kDa protein C05D11.5 in chromosome III | 0.002 | 0.0007 | 0.0007 |
Echinococcus granulosus | death domain containing protein | 0.0014 | 0.0002 | 0.0002 |
Toxoplasma gondii | chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 | 0.0011 | 0.00000025061 | 0.0000000000034853 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC90 (functional) | > 100 ug ml-1 | Antitubercular activity against Mycobacterium tuberculosis H37Rv after 4 days by microplate alamar blue assay | ChEMBL. | 18804379 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.