Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0542 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.2153 | 0.1704 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0542 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0003 | 0 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.757 | 0.9288 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0542 | 1 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0542 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.2153 | 0.1681 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.8077 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.757 | 0.757 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.757 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.2153 | 0.2171 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.757 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.2153 | 0.2171 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.5335 | 0.616 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0542 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0127 | 0.0127 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0542 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.8077 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0542 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.757 | 0.757 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.757 | 0.929 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.757 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.757 | 0.757 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.2153 | 0.2171 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.8077 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0956 | 0.044 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0542 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4688 | 0.4688 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2153 | 0.2153 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.8077 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0542 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.4403 | 0.4842 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.757 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.2153 | 0.1704 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.4403 | 0.4856 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.2153 | 0.1681 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2153 | 0.2153 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0542 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0651 | 0.0651 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0542 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.2153 | 0.2171 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2153 | 0.2153 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0956 | 0.044 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4688 | 0.4688 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0542 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.2153 | 0.2171 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.8869 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.5335 | 0.615 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.5335 | 0.5335 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.4403 | 0.4403 |
Plasmodium falciparum | zinc finger protein, putative | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0542 | 1 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.4688 | 0.5835 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.2153 | 0.2171 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0542 | 1 |
Onchocerca volvulus | 0.0028 | 0.4403 | 0.5 | |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.4688 | 0.5835 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2153 | 0.2153 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0542 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.