Detailed information for compound 982627

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 430.306 | Formula: C21H31BN4O5
  • H donors: 5 H acceptors: 4 LogP: 1.33 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(C[C@@H](B(O)O)NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)N1CCOCC1)C
  • InChi: 1S/C21H31BN4O5/c1-14(2)11-19(22(29)30)25-20(27)18(24-21(28)26-7-9-31-10-8-26)12-15-13-23-17-6-4-3-5-16(15)17/h3-6,13-14,18-19,23,29-30H,7-12H2,1-2H3,(H,24,28)(H,25,27)/t18-,19-/m0/s1
  • InChiKey: OQPVRSVAMRWHKP-OALUTQOASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0106 0.0584 0.0611
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0088 0.0088
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0021 0.0021
Loa Loa (eye worm) Smad1 0.0026 0.0088 0.0088
Schistosoma mansoni smad1 5 8 and 0.0026 0.0088 0.0088
Brugia malayi MH2 domain containing protein 0.0026 0.0088 0.0088
Schistosoma mansoni caspase-7 (C14 family) 0.0177 0.1027 0.1027
Leishmania major 6-phosphogluconolactonase 0.0036 0.0151 0.013
Entamoeba histolytica hexokinase 1 0.1622 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0256 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0177 0.1027 0.1235
Loa Loa (eye worm) hexokinase 0.1018 0.6247 0.6247
Trypanosoma cruzi hypothetical protein, conserved 0.0917 0.5621 0.5611
Trypanosoma cruzi metacaspase, putative 0.0177 0.1027 0.1008
Trichomonas vaginalis CAMK family protein kinase 0.0407 0.2456 0.325
Trichomonas vaginalis glutaminase, putative 0.1178 0.7243 1
Entamoeba histolytica hexokinase 2 0.1622 1 1
Echinococcus granulosus Smad4 0.0026 0.0088 0.0088
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.082 0.5021 0.5021
Brugia malayi MH1 domain containing protein 0.0014 0.0017 0.0017
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0069 0.0355 0.0355
Brugia malayi Furin-like cysteine rich region family protein 0.0101 0.0559 0.0559
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0407 0.2456 0.244
Echinococcus multilocularis insulin receptor 0.0033 0.0132 0.0132
Schistosoma mansoni kinase 0.0207 0.1213 0.1213
Echinococcus multilocularis caspase 0.0661 0.4036 0.4036
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0088 0.0088
Giardia lamblia Kinase, PLK 0.0407 0.2456 0.4527
Trypanosoma brucei hexokinase, putative 0.1622 1 1
Echinococcus multilocularis 6 phosphogluconolactonase 0.0036 0.0151 0.0151
Brugia malayi glutaminase DH11.1 0.1178 0.7243 0.7243
Onchocerca volvulus 0.1622 1 1
Echinococcus multilocularis epidermal growth factor receptor 0.0101 0.0559 0.0559
Mycobacterium ulcerans glutaminase 0.1178 0.7243 1
Brugia malayi hexokinase type II 0.0516 0.3131 0.3131
Brugia malayi RNA recognition motif domain containing protein 0.006 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0516 0.3131 0.3131
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0177 0.1027 0.1027
Schistosoma mansoni hexokinase 0.1622 1 1
Schistosoma mansoni tar DNA-binding protein 0.006 0.0301 0.0301
Loa Loa (eye worm) hexokinase 0.0502 0.3045 0.3045
Schistosoma mansoni smad1 5 8 and 0.0026 0.0088 0.0088
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0856 0.5243 0.5233
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.082 0.5021 0.5021
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0034 0.014 0.014
Echinococcus multilocularis citrate lyase subunit beta protein 0.0106 0.0584 0.0584
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0303 0.1813 0.2344
Schistosoma mansoni caspase-7 (C14 family) 0.0661 0.4036 0.4036
Loa Loa (eye worm) transcription factor SMAD2 0.0377 0.227 0.227
Schistosoma mansoni tyrosine kinase 0.0067 0.0347 0.0347
Brugia malayi TAR-binding protein 0.006 0.0301 0.0301
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0303 0.1813 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0088 0.0088
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0021 0.0021
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0407 0.2456 0.2456
Trypanosoma brucei beta lactamase 0.0146 0.0833 0.0813
Schistosoma mansoni caspase-3 (C14 family) 0.0661 0.4036 0.4036
Echinococcus multilocularis hexokinase 0.1622 1 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0407 0.2456 0.2456
Trypanosoma cruzi metacaspase, putative 0.0177 0.1027 0.1008
Schistosoma mansoni 6-phosphogluconolactonase 0.0036 0.0151 0.0151
Echinococcus multilocularis hexokinase type 2 0.1622 1 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0021 0.0021
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0036 0.0151 0.0011
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0177 0.1027 0.1008
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0856 0.5243 1
Echinococcus granulosus caspase 8 0.0177 0.1027 0.1027
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0021 0.0021
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.082 0.5021 0.5021
Schistosoma mansoni hypothetical protein 0.0034 0.014 0.014
Plasmodium vivax hypothetical protein, conserved 0.0177 0.1027 0.1008
Onchocerca volvulus 0.1622 1 1
Loa Loa (eye worm) nuclear factor I 0.0014 0.0017 0.0017
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0088 0.0088
Loa Loa (eye worm) TK/INSR protein kinase 0.0033 0.0132 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0177 0.1027 0.1235
Plasmodium falciparum hexokinase 0.1622 1 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0256 0.0256
Schistosoma mansoni tyrosine kinase 0.0054 0.0263 0.0263
Echinococcus multilocularis caspase 8 0.0177 0.1027 0.1027
Trypanosoma cruzi metacaspase, putative 0.0177 0.1027 0.1008
Echinococcus granulosus smad 0.0026 0.0088 0.0088
Schistosoma mansoni tyrosine kinase 0.0055 0.0268 0.0268
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0034 0.014 0.014
Trichomonas vaginalis CAMK family protein kinase 0.0407 0.2456 0.325
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0106 0.0584 0.0611
Onchocerca volvulus Hexokinase homolog 0.1018 0.6247 0.6247
Trypanosoma cruzi hexokinase, putative 0.1622 1 1
Schistosoma mansoni tar DNA-binding protein 0.006 0.0301 0.0301
Trypanosoma brucei metacaspase 5, putative 0.0177 0.1027 0.1008
Trypanosoma brucei hypothetical protein, conserved 0.0917 0.5621 0.5611
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.118 0.1451
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0256 0.0256
Brugia malayi hypothetical protein 0.0034 0.014 0.014
Trypanosoma cruzi glucosamine-6-phosphate isomerase, putative 0.0036 0.0151 0.013
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.082 0.5021 0.4944
Mycobacterium tuberculosis Conserved protein 0.0106 0.0584 0.3141
Loa Loa (eye worm) TAR-binding protein 0.006 0.0301 0.0301
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0033 0.0132 0.0132
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0106 0.0584 0.0611
Echinococcus granulosus hexokinase 0.1622 1 1
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0272 0.1616 0.1598
Trypanosoma cruzi polo-like protein kinase, putative 0.0407 0.2456 0.244
Plasmodium falciparum metacaspase 1 0.0177 0.1027 0.1008
Echinococcus multilocularis epidermal growth factor receptor 0.0055 0.0268 0.0268
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.082 0.5021 0.501
Schistosoma mansoni smad1 5 8 and 0.0026 0.0088 0.0088
Trichomonas vaginalis CAMK family protein kinase 0.0407 0.2456 0.325
Echinococcus granulosus caspase 3 0.0485 0.2938 0.2938
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0021 0.0021
Schistosoma mansoni tyrosine kinase 0.0055 0.0268 0.0268
Trypanosoma brucei metacaspase MCA3 0.0177 0.1027 0.1008
Onchocerca volvulus 0.1622 1 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.006 0.0301 0.0301
Echinococcus multilocularis caspase 3 0.0485 0.2938 0.2938
Brugia malayi Smad1 0.0026 0.0088 0.0088
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0021 0.0021
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0856 0.5243 0.718
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0661 0.4036 0.4036
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0536 0.3254 0.324
Trichomonas vaginalis CAMK family protein kinase 0.0407 0.2456 0.325
Loa Loa (eye worm) glutaminase 0.1178 0.7243 0.7243
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0177 0.1027 0.1235
Loa Loa (eye worm) 6-phosphogluconolactonase 0.0036 0.0151 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0177 0.1027 0.1235
Brugia malayi glucose-6-phosphate dehydrogenase 0.082 0.5021 0.5021
Echinococcus granulosus hexokinase type 2 0.1622 1 1
Echinococcus multilocularis smad 0.0026 0.0088 0.0088
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0033 0.0132 0.0132
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0088 0.0088
Schistosoma mansoni tyrosine kinase 0.0033 0.0132 0.0132
Echinococcus granulosus tar DNA binding protein 0.006 0.0301 0.0301
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0106 0.0584 0.3141
Schistosoma mansoni serine/threonine protein kinase 0.0407 0.2456 0.2456
Trypanosoma cruzi metacaspase 5, putative 0.0177 0.1027 0.1008
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.082 0.5021 0.501
Schistosoma mansoni glutaminase 0.1178 0.7243 0.7243
Brugia malayi serine/threonine-protein kinase plk-2 0.0407 0.2456 0.2456
Schistosoma mansoni 6-phosphogluconolactonase 0.0036 0.0151 0.0151
Echinococcus granulosus 6 phosphogluconolactonase 0.0036 0.0151 0.0151
Brugia malayi 6-phosphogluconolactonase family protein 0.0036 0.0151 0.0151
Trypanosoma brucei glucosamine-6-phosphate isomerase, putative 0.0036 0.0151 0.013
Entamoeba histolytica serine/threonine protein kinase, putative 0.0407 0.2456 0.2349
Leishmania major hypothetical protein, conserved 0.0917 0.5621 0.5611
Echinococcus granulosus citrate lyase subunit beta protein 0.0106 0.0584 0.0584
Schistosoma mansoni smad 0.0026 0.0088 0.0088
Loa Loa (eye worm) RNA binding protein 0.006 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0177 0.1027 0.1027
Trypanosoma brucei metacaspase 0.0177 0.1027 0.1008
Trypanosoma cruzi metacaspase, putative 0.0177 0.1027 0.1008
Schistosoma mansoni Smad4 0.0026 0.0088 0.0088
Plasmodium falciparum metacaspase-like protein 0.0177 0.1027 0.1008
Mycobacterium ulcerans hypothetical protein 0.0106 0.0584 0.0611
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0177 0.1027 0.1235
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0055 0.0268 0.0268
Trypanosoma cruzi polo-like protein kinase, putative 0.0407 0.2456 0.244
Leishmania major metacaspase, putative 0.0177 0.1027 0.1008
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0284 0.1695 0.9342
Loa Loa (eye worm) hexokinase type II 0.1622 1 1
Brugia malayi MH2 domain containing protein 0.0026 0.0088 0.0088
Loa Loa (eye worm) hexokinase 0.1622 1 1
Brugia malayi MH1 domain containing protein 0.0026 0.0088 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0177 0.1027 0.1235
Brugia malayi Hexokinase family protein 0.1018 0.6247 0.6247
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0856 0.5243 0.718
Echinococcus granulosus hexokinase 0.1622 1 1
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0106 0.0584 0.0564
Loa Loa (eye worm) hypothetical protein 0.0516 0.3131 0.3131
Trichomonas vaginalis conserved hypothetical protein 0.0177 0.1027 0.1235
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0177 0.1027 0.1235
Onchocerca volvulus 0.1018 0.6247 0.6247
Schistosoma mansoni tyrosine kinase 0.0033 0.0132 0.0132
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0146 0.0833 0.4531
Schistosoma mansoni tar DNA-binding protein 0.006 0.0301 0.0301
Brugia malayi RNA binding protein 0.006 0.0301 0.0301
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0106 0.0584 0.0564
Brugia malayi Hexokinase family protein 0.0502 0.3045 0.3045
Echinococcus multilocularis hexokinase 0.1622 1 1
Mycobacterium ulcerans hypothetical protein 0.0106 0.0584 0.0611
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0661 0.4036 0.4036
Schistosoma mansoni tyrosine kinase 0.0054 0.0263 0.0263
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0856 0.5243 0.5233
Echinococcus granulosus caspase 0.0661 0.4036 0.4036
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0177 0.1027 0.1027
Toxoplasma gondii hexokinase 0.1622 1 1
Echinococcus granulosus epidermal growth factor receptor 0.0055 0.0268 0.0268
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0177 0.1027 0.1008
Loa Loa (eye worm) hypothetical protein 0.1106 0.6798 0.6798
Plasmodium vivax metacaspase 1, putative 0.0177 0.1027 0.1008
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.082 0.5021 1
Brugia malayi Hexokinase family protein 0.1622 1 1
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0264 0.1567 0.1549
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0177 0.1027 0.1235
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0177 0.1027 0.1235
Onchocerca volvulus Serine\/threonine kinase homolog 0.0407 0.2456 0.2456
Trypanosoma cruzi hypothetical protein, conserved 0.0917 0.5621 0.5611
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0856 0.5243 0.718
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0017
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0021 0.0021
Schistosoma mansoni tyrosine kinase 0.0054 0.0263 0.0263
Brugia malayi Cell death protein 3 precursor 0.0177 0.1027 0.1027
Trypanosoma brucei hexokinase 0.1622 1 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0177 0.1027 0.1235
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.0256 0.0256
Trichomonas vaginalis CAMK family protein kinase 0.0407 0.2456 0.325
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0177 0.1027 0.1235
Schistosoma mansoni tyrosine kinase 0.0101 0.0559 0.0559
Brugia malayi MH2 domain containing protein 0.0377 0.227 0.227
Echinococcus granulosus caspase 2 0.0177 0.1027 0.1027
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.082 0.5021 0.6867
Trichomonas vaginalis conserved hypothetical protein 0.0177 0.1027 0.1235
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.082 0.5021 0.5021
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0407 0.2456 0.2456
Brugia malayi isocitrate dehydrogenase 0.0015 0.0021 0.0021
Plasmodium vivax hexokinase, putative 0.1622 1 1
Echinococcus multilocularis hexokinase 0.1622 1 1
Loa Loa (eye worm) hexokinase 0.1622 1 1
Trypanosoma cruzi hexokinase, putative 0.1622 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0256 0.0256
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0256 0.0256
Trypanosoma cruzi glucosamine-6-phosphate isomerase, putative 0.0036 0.0151 0.013
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.0256 0.0256
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0177 0.1027 0.1008
Loa Loa (eye worm) MH2 domain-containing protein 0.0377 0.227 0.227
Trypanosoma brucei metacaspase MCA2 0.0177 0.1027 0.1008
Trypanosoma cruzi 6-phosphogluconolactonase, putative 0.0036 0.0151 0.013
Trypanosoma cruzi metacaspase 5, putative 0.0177 0.1027 0.1008
Schistosoma mansoni transcription factor LCR-F1 0.0034 0.014 0.014
Trypanosoma cruzi 6-phosphogluconolactonase, putative 0.0036 0.0151 0.013
Loa Loa (eye worm) TK/EGFR protein kinase 0.0101 0.0559 0.0559
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0021 0.0021
Echinococcus granulosus hexokinase 0.1622 1 1
Trypanosoma brucei polo-like protein kinase 0.0407 0.2456 0.244
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.118 0.1451
Treponema pallidum hexokinase (hxk) 0.1622 1 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0177 0.1027 0.1235
Echinococcus multilocularis caspase 2 0.0177 0.1027 0.1027
Echinococcus multilocularis 0.0031 0.0123 0.0123
Trypanosoma brucei Metacaspase-4 0.0177 0.1027 0.1008
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0106 0.0584 0.0611
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.082 0.5021 0.501
Trypanosoma brucei hexokinase 0.1622 1 1
Schistosoma mansoni tar DNA-binding protein 0.006 0.0301 0.0301
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0536 0.3254 0.4376
Leishmania major glucosamine-6-phosphate isomerase, putative 0.0036 0.0151 0.013
Schistosoma mansoni glucosamine-6-phosphate isomerase 0.0036 0.0151 0.0151
Trypanosoma brucei 6-phosphogluconolactonase 0.0036 0.0151 0.013
Brugia malayi MH1 domain containing protein 0.0026 0.0088 0.0088
Leishmania major hexokinase, putative 0.1622 1 1
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0106 0.0584 0.0564
Echinococcus multilocularis tar DNA binding protein 0.006 0.0301 0.0301
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0177 0.1027 0.1235
Loa Loa (eye worm) hypothetical protein 0.0177 0.1027 0.1027
Brugia malayi MH1 domain containing protein 0.0014 0.0017 0.0017
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0856 0.5243 0.5233
Trichomonas vaginalis CAMK family protein kinase 0.0407 0.2456 0.325
Brugia malayi Protein kinase domain containing protein 0.0033 0.0132 0.0132
Echinococcus granulosus insulin receptor 0.0033 0.0132 0.0132
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0256 0.0256
Echinococcus granulosus epidermal growth factor receptor 0.0101 0.0559 0.0559
Onchocerca volvulus Cell death protein 3 homolog 0.0177 0.1027 0.1027
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0069 0.0355 0.0355
Leishmania major hexokinase, putative 0.1622 1 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0088 0.0088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0256 0.0256
Loa Loa (eye worm) glutaminase 2 0.1178 0.7243 0.7243
Mycobacterium ulcerans lipoprotein LpqF 0.0146 0.0833 0.0962
Trichomonas vaginalis CAMK family protein kinase 0.0407 0.2456 0.325
Echinococcus multilocularis Smad4 0.0026 0.0088 0.0088
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0021 0.0021
Schistosoma mansoni tar DNA-binding protein 0.006 0.0301 0.0301
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0146 0.0833 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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