Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Sus scrofa | Type-1 angiotensin II receptor | Starlite/ChEMBL | References |
Rattus norvegicus | Type-1A angiotensin II receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | hexose transporter | 0.0031 | 0.0615 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.0615 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.0615 | 0.5 |
Trypanosoma brucei | glucose transporter 2A | 0.0031 | 0.0615 | 0.5 |
Leishmania major | glucose transporter, lmgt3 | 0.0031 | 0.0615 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0102 | 0.3632 | 0.3769 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0031 | 0.0615 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0031 | 0.0615 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0102 | 0.3632 | 0.3769 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0102 | 0.3632 | 0.3769 |
Echinococcus multilocularis | General substrate transporter | 0.0087 | 0.3017 | 0.3126 |
Leishmania major | glucose transporter, lmgt1 | 0.0031 | 0.0615 | 0.5 |
Loa Loa (eye worm) | sugar transporter | 0.0102 | 0.3632 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.0615 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0102 | 0.3632 | 0.3616 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0249 | 1 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.0615 | 0.5 |
Echinococcus granulosus | General substrate transporter | 0.0087 | 0.3017 | 0.2999 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0018 | 0.0026 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0031 | 0.0615 | 1 |
Trypanosoma brucei | glucose transporter 1E | 0.0031 | 0.0615 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.0615 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0031 | 0.0615 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0102 | 0.3632 | 1 |
Brugia malayi | Sugar transporter family protein | 0.0102 | 0.3632 | 1 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0102 | 0.3632 | 0.3616 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.0615 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0102 | 0.3632 | 0.3616 |
Plasmodium falciparum | hexose transporter | 0.0102 | 0.3632 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.0615 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0102 | 0.3632 | 0.3616 |
Trypanosoma cruzi | hexose transporter, putative | 0.0031 | 0.0615 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0018 | 0.0026 | 0.5 |
Leishmania major | glucose transporter, lmgt2 | 0.0031 | 0.0615 | 0.5 |
Onchocerca volvulus | 0.0018 | 0.0026 | 0.5 | |
Plasmodium vivax | hexose transporter | 0.0102 | 0.3632 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0031 | 0.0615 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0102 | 0.3632 | 0.3769 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0031 | 0.0615 | 0.5 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0102 | 0.3632 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.0615 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0102 | 0.3632 | 0.3616 |
Schistosoma mansoni | glucose transport protein | 0.0102 | 0.3632 | 0.3616 |
Schistosoma mansoni | glucose transport protein | 0.0102 | 0.3632 | 0.3616 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.3632 | 0.3616 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.024 | 0.9595 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0018 | 0.0026 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.