Detailed information for compound 983897

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 484.719 | Formula: C32H44N4++
  • H donors: 2 H acceptors: 0 LogP: 7.45 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1ccc2c(c1)c1c(cc2)c(N)cc([n+]1CCCCCCCCCC[N+](C)(C)C)c1ccccc1
  • InChi: 1S/C32H43N4/c1-36(2,3)22-14-9-7-5-4-6-8-13-21-35-31(26-15-11-10-12-16-26)24-30(34)28-20-18-25-17-19-27(33)23-29(25)32(28)35/h10-12,15-20,23-24,34H,4-9,13-14,21-22,33H2,1-3H3/q+1/p+1
  • InChiKey: KGCZCAVBXYUHTB-UHFFFAOYSA-O  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0991 0.2083
Schistosoma mansoni lamin 0.0029 0.0266 0.0684
Toxoplasma gondii superoxide dismutase SOD2 0.0076 0.1213 0.2569
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0454 0.8749 1
Brugia malayi Cytochrome P450 family protein 0.0029 0.0263 0.03
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0076 0.1213 0.1109
Schistosoma mansoni transcription factor LCR-F1 0.0078 0.1242 0.3682
Schistosoma mansoni inositol monophosphatase 0.0041 0.0514 0.1443
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0266 0.0305
Brugia malayi heat shock protein 90 0.0035 0.0384 0.0439
Trypanosoma cruzi iron superoxide dismutase, putative 0.0076 0.1213 1
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0122 0.0172
Schistosoma mansoni hypothetical protein 0.0181 0.3299 1
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0028 0.0243 0.1708
Echinococcus granulosus muscleblind protein 0.0159 0.2872 0.4033
Echinococcus granulosus intermediate filament protein 0.0029 0.0266 0.0318
Echinococcus multilocularis endoplasmin 0.0028 0.0243 0.0285
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Loa Loa (eye worm) hypothetical protein 0.0022 0.0122 0.014
Brugia malayi Inositol-1 0.0041 0.0514 0.0587
Plasmodium falciparum thioredoxin 3 0.0246 0.4594 1
Schistosoma mansoni heat shock protein 0.0035 0.0384 0.1046
Trypanosoma brucei iron superoxide dismutase C, mitochondrial 0.0043 0.0555 0.437
Echinococcus multilocularis muscleblind protein 1 0.0159 0.2872 0.4033
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0719 0.0822
Echinococcus multilocularis expressed conserved protein 0.0099 0.1661 0.2306
Loa Loa (eye worm) hypothetical protein 0.0076 0.1213 0.1386
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0122 0.0112
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0243 0.0128
Trichomonas vaginalis superoxide dismutase, putative 0.0076 0.1213 0.1109
Loa Loa (eye worm) hypothetical protein 0.0055 0.0794 0.0908
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0243 0.0128
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0078 0.1242 0.1709
Trichomonas vaginalis superoxide dismutase, putative 0.0076 0.1213 0.1109
Entamoeba histolytica hypothetical protein 0.0078 0.1242 0.6112
Brugia malayi hypothetical protein 0.0252 0.4725 0.5401
Plasmodium vivax heat shock protein 86, putative 0.0035 0.0384 0.0748
Onchocerca volvulus 0.0337 0.6411 0.6367
Brugia malayi Pre-SET motif family protein 0.0065 0.0991 0.1133
Trypanosoma cruzi Heat shock protein 83, putative 0.0035 0.0384 0.2913
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.0384 0.2913
Plasmodium vivax endoplasmin, putative 0.0035 0.0384 0.0748
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0514 0.2788
Echinococcus granulosus heat shock protein 90 0.0035 0.0384 0.0486
Loa Loa (eye worm) inositol-1 0.0041 0.0514 0.0587
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.077 0.2232
Onchocerca volvulus 0.0029 0.0266 0.0146
Leishmania major superoxide dismutase, putative 0.0043 0.0555 0.437
Trypanosoma cruzi iron superoxide dismutase, putative 0.0052 0.073 0.5871
Echinococcus granulosus lamin dm0 0.0029 0.0266 0.0318
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0991 0.2911
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0592 0.048
Brugia malayi hypothetical protein 0.0022 0.0122 0.014
Trypanosoma cruzi superoxide dismutase, putative 0.0043 0.0555 0.437
Trypanosoma cruzi iron superoxide dismutase A, mitochondrial 0.0076 0.1213 1
Mycobacterium tuberculosis Superoxide dismutase [FE] SodA 0.0076 0.1213 1
Loa Loa (eye worm) heat shock protein 90 0.0035 0.0384 0.0439
Schistosoma mansoni superoxide dismutase [mn] 0.0076 0.1213 0.3591
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0122 0.0112
Schistosoma mansoni survival motor neuron protein 0.0051 0.0719 0.2075
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0384 0.2913
Loa Loa (eye worm) hypothetical protein 0.0159 0.2872 0.3282
Loa Loa (eye worm) hypothetical protein 0.0065 0.0991 0.1133
Schistosoma mansoni rab6-interacting 0.0022 0.0122 0.0241
Plasmodium vivax superoxide dismutase [Fe], putative 0.0076 0.1213 0.2569
Echinococcus multilocularis musashi 0.0029 0.0266 0.0318
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0428 0.19
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Trypanosoma cruzi superoxide dismutase, putative 0.0019 0.0072 0.0242
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0122 0.0112
Echinococcus multilocularis Niemann Pick C1 protein 0.0105 0.1788 0.2488
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.0384 0.2913
Trypanosoma brucei heat shock protein, putative 0.0035 0.0384 0.2913
Echinococcus granulosus lamin 0.0029 0.0266 0.0318
Entamoeba histolytica hypothetical protein 0.0078 0.1242 0.6112
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Schistosoma mansoni endoplasmin 0.0035 0.0384 0.1046
Echinococcus multilocularis survival motor neuron protein 1 0.0252 0.4725 0.6677
Echinococcus granulosus geminin 0.0181 0.3299 0.4643
Echinococcus multilocularis tumor protein p63 0.0369 0.7055 1
Schistosoma mansoni lamin 0.0029 0.0266 0.0684
Trypanosoma cruzi superoxide dismutase, putative 0.0043 0.0555 0.437
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0514 0.1033
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0044 0.005
Mycobacterium leprae Probable superoxide dismutase SodA 0.0076 0.1213 1
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Schistosoma mansoni hypothetical protein 0.0181 0.3299 1
Brugia malayi hypothetical protein 0.0078 0.1242 0.142
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0122 0.014
Trichomonas vaginalis heat shock protein, putative 0.0035 0.0384 0.0271
Trypanosoma brucei iron superoxide dismutase 0.0076 0.1213 1
Toxoplasma gondii superoxide dismutase SOD3 0.0076 0.1213 0.2569
Schistosoma mansoni hypothetical protein 0.0051 0.0719 0.2075
Echinococcus granulosus heat shock protein 90 0.0028 0.0243 0.0285
Loa Loa (eye worm) hypothetical protein 0.0054 0.077 0.088
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0991 0.2911
Mycobacterium ulcerans superoxide dismutase [Fe] SodA 0.0076 0.1213 1
Schistosoma mansoni heat shock protein 0.0035 0.0384 0.1046
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0514 0.067
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0592 0.0782
Loa Loa (eye worm) hypothetical protein 0.0028 0.0256 0.0293
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0263 0.03
Echinococcus granulosus manganese superoxide dismutase 0.0076 0.1213 0.1667
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0514 0.0922
Loa Loa (eye worm) hypothetical protein 0.0022 0.0122 0.014
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0514 0.402
Treponema pallidum heat shock protein 90 0.0028 0.0243 0.5
Giardia lamblia Heat shock protein HSP 90-alpha 0.0035 0.0384 1
Schistosoma mansoni lipoxygenase 0.009 0.1489 0.444
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0384 0.2913
Brugia malayi CHE-14 protein 0.0045 0.0592 0.0676
Echinococcus granulosus endoplasmin 0.0028 0.0243 0.0285
Entamoeba histolytica hypothetical protein 0.0078 0.1242 0.6112
Trypanosoma cruzi superoxide dismutase, putative 0.0043 0.0555 0.437
Trypanosoma cruzi heat shock protein 90, putative 0.0028 0.0243 0.1708
Echinococcus granulosus expressed conserved protein 0.0099 0.1661 0.2306
Leishmania major superoxide dismutase, putative 0.0043 0.0555 0.437
Loa Loa (eye worm) hypothetical protein 0.0337 0.6411 0.7328
Loa Loa (eye worm) hypothetical protein 0.0159 0.2872 0.3282
Toxoplasma gondii superoxide dismutase 0.0076 0.1213 0.2569
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0514 0.402
Trypanosoma brucei iron superoxide dismutase 0.0076 0.1213 1
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Schistosoma mansoni intermediate filament proteins 0.0029 0.0266 0.0684
Plasmodium vivax thioredoxin 3, putative 0.0246 0.4594 1
Schistosoma mansoni endoplasmin 0.0035 0.0384 0.1046
Onchocerca volvulus 0.0054 0.077 0.0656
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0514 0.0401
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0514 0.402
Schistosoma mansoni rab6-interacting 0.0022 0.0122 0.0241
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.0991 0.1352
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0266 0.0305
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Echinococcus multilocularis Niemann Pick C1 protein 0.015 0.2687 0.377
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Schistosoma mansoni patched 1 0.0045 0.0592 0.1683
Schistosoma mansoni hypothetical protein 0.0078 0.1242 0.3682
Trypanosoma cruzi Iron/manganese superoxide dismutases, C-terminal domain containing protein, putative 0.0019 0.0072 0.0242
Loa Loa (eye worm) hypothetical protein 0.0029 0.0266 0.0305
Onchocerca volvulus 0.0029 0.0266 0.0146
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0076 0.1213 0.1104
Trypanosoma brucei heat shock protein, putative 0.0035 0.0384 0.2913
Trypanosoma cruzi iron superoxide dismutase A, mitochondrial 0.0076 0.1213 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0122 0.0112
Brugia malayi Endoplasmin precursor 0.0035 0.0384 0.0439
Loa Loa (eye worm) hypothetical protein 0.0252 0.4725 0.5401
Trypanosoma cruzi iron superoxide dismutase, putative 0.0076 0.1213 1
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0076 0.1213 0.1104
Echinococcus multilocularis lamin 0.0029 0.0266 0.0318
Brugia malayi isocitrate dehydrogenase 0.0018 0.0044 0.005
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.0991 0.1352
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0076 0.1213 0.1109
Entamoeba histolytica hypothetical protein 0.0078 0.1242 0.6112
Trichomonas vaginalis iron superoxide dismutase A, putative 0.0076 0.1213 0.1109
Trypanosoma cruzi Iron/manganese superoxide dismutases, C-terminal domain containing protein, putative 0.0019 0.0072 0.0242
Echinococcus granulosus tumor protein p63 0.0369 0.7055 1
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0266 0.0305
Plasmodium vivax SET domain protein, putative 0.0065 0.0991 0.2083
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0028 0.0243 0.0285
Wolbachia endosymbiont of Brugia malayi superoxide dismutase, SodA 0.0076 0.1213 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0129 0.2262 0.3164
Plasmodium falciparum superoxide dismutase [Fe] 0.0043 0.0555 0.1123
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0101 0.0488
Schistosoma mansoni inositol monophosphatase 0.0041 0.0514 0.1443
Entamoeba histolytica iron-containing superoxide dismutase 0.0076 0.1213 0.5901
Echinococcus multilocularis heat shock protein 0.0035 0.0384 0.0486
Plasmodium falciparum superoxide dismutase [Fe] 0.0076 0.1213 0.2569
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Schistosoma mansoni polycystin 1-related 0.0022 0.0122 0.0241
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0991 0.2911
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0243 0.0128
Brugia malayi Niemann-Pick C1 protein precursor 0.0105 0.1788 0.2044
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0514 0.402
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0078 0.1242 0.1709
Schistosoma mansoni hypothetical protein 0.0022 0.0122 0.0241
Schistosoma mansoni loxhd1 0.0022 0.0122 0.0241
Echinococcus granulosus heat shock protein 0.0035 0.0384 0.0486
Trypanosoma brucei Heat shock protein 83, putative 0.0035 0.0384 0.2913
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0991 0.1352
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0052 0.073 0.0615
Trypanosoma brucei heat shock protein, putative 0.0035 0.0384 0.2913
Trichomonas vaginalis superoxide dismutase [mn], putative 0.0076 0.1213 0.1109
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0384 0.2913
Echinococcus granulosus survival motor neuron protein 1 0.0252 0.4725 0.6677
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0129 0.2262 0.3164
Brugia malayi Muscleblind-like protein 0.0159 0.2872 0.3282
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Trypanosoma cruzi heat shock protein 85, putative 0.0028 0.0243 0.1708
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0514 0.2788
Trypanosoma brucei heat shock protein, putative 0.0035 0.0384 0.2913
Leishmania major iron superoxide dismutase, putative 0.0076 0.1213 1
Brugia malayi hypothetical protein 0.0337 0.6411 0.7328
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0028 0.0243 0.1708
Trypanosoma brucei heat shock protein, putative 0.0035 0.0384 0.2913
Brugia malayi Superoxide dismutase, mitochondrial precursor, putative 0.0076 0.1213 0.1386
Toxoplasma gondii thioredoxin domain-containing protein 0.0246 0.4594 1
Toxoplasma gondii heat shock protein 90, putative 0.0035 0.0384 0.0748
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0592 0.0782
Onchocerca volvulus 0.0065 0.0991 0.088
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0063 0.0944 0.1284
Trypanosoma brucei Mitochondrial SSU ribosomal protein, putative 0.0019 0.0072 0.0242
Loa Loa (eye worm) endoplasmin 0.0035 0.0384 0.0439
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0428 0.3284
Echinococcus multilocularis manganese superoxide dismutase 0.0076 0.1213 0.1667
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0105 0.1788 1
Plasmodium vivax superoxide dismutase [Fe], putative 0.0043 0.0555 0.1123
Echinococcus granulosus Niemann Pick C1 protein 0.0105 0.1788 0.2488
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0122 0.0172
Brugia malayi intermediate filament protein 0.0029 0.0266 0.0305
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0592 0.0782
Schistosoma mansoni lipoxygenase 0.0129 0.2262 0.6816
Schistosoma mansoni hypothetical protein 0.0043 0.0559 0.1584
Schistosoma mansoni hypothetical protein 0.0043 0.0559 0.1584
Schistosoma mansoni hypothetical protein 0.0043 0.0559 0.1584
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0076 0.1213 0.1109
Trypanosoma brucei iron superoxide dismutase A, mitochondrial 0.0076 0.1213 1
Trypanosoma cruzi iron superoxide dismutase, putative 0.0076 0.1213 1
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Trypanosoma cruzi heat shock protein 90, putative 0.0035 0.0384 0.2913
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Trypanosoma brucei heat shock protein, putative 0.0035 0.0384 0.2913
Echinococcus multilocularis heat shock protein 90 0.0035 0.0384 0.0486
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Chlamydia trachomatis superoxide dismutase 0.0076 0.1213 0.5
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Trypanosoma brucei superoxide dismutase, putative 0.0043 0.0555 0.437
Brugia malayi Pre-SET motif family protein 0.0454 0.8749 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0991 0.2911
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Echinococcus granulosus Niemann Pick C1 protein 0.015 0.2687 0.377
Plasmodium falciparum endoplasmin, putative 0.0021 0.0117 0.0161
Toxoplasma gondii heat shock protein HSP90 0.0035 0.0384 0.0748
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0044 0.005
Echinococcus multilocularis heat shock protein 90 0.0028 0.0243 0.0285
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Loa Loa (eye worm) hypothetical protein 0.0105 0.1788 0.2044
Loa Loa (eye worm) hypothetical protein 0.0045 0.0592 0.0676
Leishmania major heat shock protein 83-1 0.0035 0.0384 0.2913
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0592 0.0676
Brugia malayi hypothetical protein 0.0022 0.0122 0.014
Leishmania major iron superoxide dismutase, putative 0.0076 0.1213 1
Leishmania major iron superoxide dismutase 0.0076 0.1213 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0514 0.0401
Trypanosoma brucei heat shock protein, putative 0.0035 0.0384 0.2913
Echinococcus multilocularis muscleblind protein 0.0159 0.2872 0.4033
Onchocerca volvulus 0.0051 0.0719 0.0604
Schistosoma mansoni hypothetical protein 0.0043 0.0559 0.1584
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0107 0.182 0.5458
Trypanosoma cruzi superoxide dismutase, putative 0.0043 0.0555 0.437
Echinococcus multilocularis lamin dm0 0.0029 0.0266 0.0318
Echinococcus multilocularis RUN 0.0022 0.0122 0.0112
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0514 0.067
Brugia malayi Doublecortin family protein 0.0022 0.0122 0.014
Plasmodium falciparum heat shock protein 90 0.0035 0.0384 0.0748
Echinococcus multilocularis protein dispatched 1 0.0051 0.0719 0.0963
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0514 0.0401
Echinococcus multilocularis geminin 0.0181 0.3299 0.4643
Echinococcus granulosus RUN 0.0022 0.0122 0.0112
Trichomonas vaginalis set domain proteins, putative 0.0517 1 1
Echinococcus multilocularis protein patched 0.0045 0.0592 0.0782
Trypanosoma brucei heat shock protein, putative 0.0035 0.0384 0.2913
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0122 0.0112
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0122 0.0112

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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