Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0078 | 0.0414 | 0.7056 | |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0017 | 0.0203 |
Brugia malayi | Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog | 0.0034 | 0.0123 | 0.1487 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.155 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0299 | 0.185 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0078 | 0.0414 | 0.3431 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0522 | 0.3302 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0299 | 0.185 | 1 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0034 | 0.0123 | 0.1487 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0017 | 0.0051 |
Echinococcus multilocularis | sodium channel protein | 0.0522 | 0.3302 | 1 |
Onchocerca volvulus | 0.0029 | 0.0091 | 0.1549 | |
Leishmania major | cathepsin L-like protease | 0.0299 | 0.185 | 0.5432 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0105 | 0.0587 | 0.2685 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0017 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0034 | 0.0123 | 0.0371 |
Brugia malayi | hypothetical protein | 0.0142 | 0.0825 | 1 |
Schistosoma mansoni | cathepsin s | 0.0026 | 0.0072 | 0.0594 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0105 | 0.0587 | 0.047 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.155 | 1 | 1 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Plasmodium vivax | unspecified product | 0.004 | 0.0166 | 0.0095 |
Echinococcus granulosus | calcium activated potassium channel | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | ion channel NompC | 0.0034 | 0.0123 | 0.1487 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | sex comb on midleg homolog | 0.003 | 0.0101 | 0.0841 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0299 | 0.185 | 1 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0034 | 0.0123 | 0.1487 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0149 | 0.1235 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.004 | 0.0166 | 0.1376 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0053 | 0.0248 | 0.075 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.012 | 0.0686 | 0.2076 |
Brugia malayi | Protein kinase domain containing protein | 0.0053 | 0.0248 | 0.3003 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0078 | 0.0414 | 0.5893 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0072 | 0.0869 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0142 | 0.0825 | 0.2498 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0034 | 0.0123 | 0.1017 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0034 | 0.0123 | 0.0371 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0034 | 0.0123 | 0.0371 |
Brugia malayi | Papain family cysteine protease containing protein | 0.004 | 0.0166 | 0.2013 |
Onchocerca volvulus | 0.0105 | 0.0587 | 1 | |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0034 | 0.0123 | 0.0371 |
Onchocerca volvulus | Cathepsin F homolog | 0.0078 | 0.0414 | 0.7056 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0105 | 0.0587 | 0.2895 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0587 | 0.711 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0299 | 0.185 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase 7 | 0.0052 | 0.024 | 0.0726 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit | 0.0034 | 0.0123 | 0.1487 |
Echinococcus multilocularis | voltage gated hydrogen channel 1 | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0393 | 0.4765 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | sodium channel protein | 0.0522 | 0.3302 | 1 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.003 | 0.0101 | 0.0307 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0034 | 0.0123 | 0.1017 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1487 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0034 | 0.0123 | 0.0371 |
Onchocerca volvulus | 0.0078 | 0.0414 | 0.7056 | |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0034 | 0.0123 | 0.0371 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0078 | 0.0414 | 0.1253 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0034 | 0.0123 | 0.0371 |
Onchocerca volvulus | 0.0078 | 0.0414 | 0.7056 | |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.004 | 0.0166 | 0.1376 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0231 | 0.07 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0522 | 0.3302 | 1 |
Echinococcus granulosus | two pore calcium channel protein 1 | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | calcium channel | 0.0034 | 0.0123 | 0.1487 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.155 | 1 | 1 |
Brugia malayi | Transient-receptor-potential like protein | 0.0034 | 0.0123 | 0.1487 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | sodium leak channel non selective protein | 0.0034 | 0.0123 | 0.0371 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0414 | 0.5017 |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0034 | 0.0123 | 0.1487 |
Echinococcus multilocularis | kinase protein | 0.0052 | 0.024 | 0.0726 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0299 | 0.185 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog | 0.0034 | 0.0123 | 0.1487 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0078 | 0.0414 | 0.1253 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0075 | 0.0393 | 0.119 |
Loa Loa (eye worm) | fibroinase | 0.0078 | 0.0414 | 0.5017 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.003 | 0.0101 | 0.0307 |
Trypanosoma cruzi | cysteine protease, putative | 0.004 | 0.0166 | 0.053 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Onchocerca volvulus | 0.0078 | 0.0414 | 0.7056 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0017 | 0.0203 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0034 | 0.0123 | 0.1487 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0414 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0245 | 0.2968 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0299 | 0.185 | 1 |
Brugia malayi | olfactory channel protein osm-9 | 0.0034 | 0.0123 | 0.1487 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0299 | 0.185 | 1 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0105 | 0.0587 | 0.1776 |
Brugia malayi | voltage-dependent calcium channel | 0.0034 | 0.0123 | 0.1487 |
Loa Loa (eye worm) | MBCTL1 | 0.0035 | 0.0129 | 0.1563 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | two-pore calcium channel | 0.0034 | 0.0123 | 0.1017 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0034 | 0.0123 | 0.2091 |
Schistosoma mansoni | transient receptor potential channel | 0.0034 | 0.0123 | 0.1017 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0825 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0299 | 0.185 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Brugia malayi | Ryanodine Receptor TM 4-6 family protein | 0.0034 | 0.0123 | 0.1487 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.003 | 0.0101 | 0.0841 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0034 | 0.0123 | 0.1017 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0034 | 0.0123 | 0.1017 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.012 | 0.0686 | 0.2076 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit | 0.0034 | 0.0123 | 0.1487 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0017 | 0.0203 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0078 | 0.0414 | 0.1253 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0034 | 0.0123 | 0.0371 |
Entamoeba histolytica | cysteine protease, putative | 0.0078 | 0.0414 | 0.5893 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0078 | 0.0414 | 0.5893 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0034 | 0.0123 | 0.0371 |
Brugia malayi | Voltage-gated calcium channel, alpha subunit | 0.0034 | 0.0123 | 0.1487 |
Brugia malayi | Cathepsin L-like precursor | 0.0053 | 0.0245 | 0.2968 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.004 | 0.0166 | 0.053 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0105 | 0.0587 | 0.711 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0078 | 0.0414 | 0.1253 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0231 | 0.2803 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.155 | 1 | 1 |
Brugia malayi | mbt repeat family protein | 0.003 | 0.0101 | 0.1229 |
Echinococcus multilocularis | kinase protein | 0.0052 | 0.024 | 0.0726 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0053 | 0.0245 | 0.1875 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0017 | 0.0051 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0017 | 0.0139 |
Echinococcus multilocularis | cysteine protease | 0.0078 | 0.0414 | 0.1253 |
Schistosoma mansoni | 60S ribosomal protein L21 | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | voltage-gated ion channel | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0034 | 0.0123 | 0.1017 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0034 | 0.0123 | 0.0371 |
Echinococcus multilocularis | transfer RNA-Gly | 0.0034 | 0.0123 | 0.0371 |
Trypanosoma brucei | pteridine reductase 1 | 0.0105 | 0.0587 | 0.2685 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0053 | 0.0245 | 0.203 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0034 | 0.0123 | 0.1487 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0231 | 0.07 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0034 | 0.0123 | 0.0371 |
Brugia malayi | mbt repeat family protein | 0.003 | 0.0101 | 0.1229 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0034 | 0.0123 | 0.1017 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0273 | 0.1681 | 0.905 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0078 | 0.0414 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0017 | 0.0139 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0034 | 0.0123 | 0.0371 |
Toxoplasma gondii | cathepsin CPL | 0.0078 | 0.0414 | 0.0295 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1487 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.0263 | 0.3189 |
Loa Loa (eye worm) | ryanodine receptor | 0.0034 | 0.0123 | 0.1487 |
Schistosoma mansoni | transient receptor potential channel | 0.0034 | 0.0123 | 0.1017 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Echinococcus granulosus | potassium channel KvQLT family member kqt 1 | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | geminin | 0.02 | 0.1206 | 0.3653 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | vesicular amine transporter | 0.0034 | 0.0123 | 0.1017 |
Loa Loa (eye worm) | voltage-gated calcium channel | 0.0034 | 0.0123 | 0.1487 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0414 | 0.5017 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | oxidoreductase | 0.0105 | 0.0587 | 0.711 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0035 | 0.0129 | 0.039 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.003 | 0.0101 | 0.0307 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0078 | 0.0414 | 0.3431 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0017 | 0.0051 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0034 | 0.0123 | 0.1487 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0072 | 0.0869 |
Echinococcus granulosus | ryanodine receptor 44f | 0.0034 | 0.0123 | 0.0371 |
Leishmania major | cysteine peptidase A (CPA) | 0.0078 | 0.0414 | 0.0916 |
Echinococcus granulosus | hypothetical protein | 0.0034 | 0.0123 | 0.0371 |
Echinococcus multilocularis | two pore calcium channel protein 1 | 0.0034 | 0.0123 | 0.0371 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0414 | 0.0916 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0245 | 0.2968 |
Echinococcus multilocularis | cysteine protease | 0.0078 | 0.0414 | 0.1253 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0034 | 0.0123 | 0.0371 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0105 | 0.0587 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0053 | 0.0245 | 0.2968 |
Plasmodium vivax | vivapain-2 | 0.0078 | 0.0414 | 0.0345 |
Trichomonas vaginalis | hypothetical protein | 0.155 | 1 | 1 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.004 | 0.0166 | 0.0503 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0393 | 0.4765 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0026 | 0.0072 | 0.0869 |
Schistosoma mansoni | hypothetical protein | 0.0185 | 0.1111 | 0.9206 |
Schistosoma mansoni | survival motor neuron protein | 0.0029 | 0.0091 | 0.0753 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0034 | 0.0123 | 0.0371 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.0166 | 0.0251 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0034 | 0.0123 | 0.0371 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | cathepsin l1 | 0.0078 | 0.0414 | 0.1253 |
Onchocerca volvulus | 0.0078 | 0.0414 | 0.7056 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Brugia malayi | ion channel NompC | 0.0034 | 0.0123 | 0.1487 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0078 | 0.0414 | 0.5017 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0078 | 0.0414 | 0.5017 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.0263 | 0.3189 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | sex comb on midleg homolog | 0.003 | 0.0101 | 0.0841 |
Onchocerca volvulus | 0.0078 | 0.0414 | 0.7056 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0299 | 0.185 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0053 | 0.0245 | 0.0741 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0017 | 0.0051 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | shaker cognate | 0.0034 | 0.0123 | 0.0371 |
Leishmania major | cathepsin L-like protease | 0.0299 | 0.185 | 0.5432 |
Echinococcus multilocularis | two pore calcium channel protein 2 | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Schistosoma mansoni | hypothetical protein | 0.02 | 0.1206 | 1 |
Leishmania major | pteridine reductase 1 | 0.0105 | 0.0587 | 0.1459 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Echinococcus multilocularis | muscleblind protein | 0.0075 | 0.0393 | 0.119 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Echinococcus granulosus | voltage gated potassium channel | 0.0034 | 0.0123 | 0.0371 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0414 | 0.0916 |
Echinococcus granulosus | potassium voltage gated channel subfamily C | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0035 | 0.0129 | 0.039 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0053 | 0.0245 | 0.2968 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0105 | 0.0587 | 0.047 |
Schistosoma mansoni | voltage-gated potassium channel KCNQ | 0.0034 | 0.0123 | 0.1017 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.003 | 0.0101 | 0.0307 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0105 | 0.0587 | 0.711 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0034 | 0.0123 | 0.0371 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0142 | 0.0825 | 0.2498 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0072 | 0.0869 |
Onchocerca volvulus | 0.0034 | 0.0123 | 0.2091 | |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0017 | 0.0051 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0105 | 0.0587 | 0.711 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0231 | 0.1917 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0245 | 0.2968 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0034 | 0.0123 | 0.0287 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0263 | 0.3189 |
Brugia malayi | Muscleblind-like protein | 0.0075 | 0.0393 | 0.4765 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0017 | 0.0139 |
Onchocerca volvulus | Cathepsin L homolog | 0.0078 | 0.0414 | 0.7056 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0078 | 0.0414 | 0.5017 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0299 | 0.185 | 1 |
Echinococcus granulosus | voltage gated potassium channel | 0.0034 | 0.0123 | 0.0371 |
Brugia malayi | Cathepsin L-like precursor | 0.0053 | 0.0245 | 0.2968 |
Onchocerca volvulus | 0.003 | 0.0101 | 0.1729 | |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Brugia malayi | Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog | 0.0034 | 0.0123 | 0.1487 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.0263 | 0.3189 |
Echinococcus granulosus | 3'partial|mitogen activated protein kinase kinase kinase | 0.0052 | 0.024 | 0.0726 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0105 | 0.0587 | 0.2895 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0029 | 0.0091 | 0.1101 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0299 | 0.185 | 1 |
Onchocerca volvulus | 0.0078 | 0.0414 | 0.7056 | |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0052 | 0.024 | 0.0726 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0105 | 0.0587 | 0.4862 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0105 | 0.0587 | 0.2685 |
Schistosoma mansoni | inositol 145-trisphosphate receptor | 0.0034 | 0.0123 | 0.1017 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Echinococcus granulosus | cathepsin L | 0.004 | 0.0166 | 0.0503 |
Trypanosoma cruzi | inositol 1,4,5-trisphosphate receptor, putative | 0.0034 | 0.0123 | 0.0287 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0034 | 0.0123 | 0.1017 |
Echinococcus multilocularis | potassium large conductance calcium activated | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Leishmania major | oxidoreductase-like protein | 0.0105 | 0.0587 | 0.1459 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0053 | 0.0249 | 0.3021 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0053 | 0.0245 | 0.0124 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0072 | 0.0869 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.155 | 1 | 1 |
Echinococcus granulosus | two pore calcium channel protein 2 | 0.0034 | 0.0123 | 0.0371 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.155 | 1 | 1 |
Echinococcus granulosus | cysteine protease | 0.004 | 0.0166 | 0.0503 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0034 | 0.0123 | 0.1017 |
Loa Loa (eye worm) | ctsf protein | 0.0078 | 0.0414 | 0.5017 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0034 | 0.0123 | 0.2091 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0034 | 0.0123 | 0.1017 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0034 | 0.0123 | 0.0371 |
Echinococcus multilocularis | sodium leak channel non selective protein | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0017 | 0.0203 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0101 | 0.1229 |
Plasmodium vivax | vivapain-3 | 0.004 | 0.0166 | 0.0095 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0017 | 0.0139 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0231 | 0.2803 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.004 | 0.0166 | 0.1376 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0149 | 0.1807 |
Echinococcus multilocularis | potassium voltage gated channel subfamily C | 0.0034 | 0.0123 | 0.0371 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.0166 | 0.0044 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0034 | 0.0123 | 0.1017 |
Loa Loa (eye worm) | TKL/MLK/TAK1 protein kinase | 0.0053 | 0.0248 | 0.3003 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.004 | 0.0166 | 0.053 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0034 | 0.0123 | 0.1487 |
Schistosoma mansoni | calcium channel voltage-dependent p/q type alpha 1a-related | 0.0034 | 0.0123 | 0.1017 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0034 | 0.0123 | 0.0371 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0105 | 0.0587 | 0.1459 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0414 | 0.1924 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | muscleblind protein | 0.0075 | 0.0393 | 0.119 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0299 | 0.185 | 1 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0034 | 0.0123 | 0.0371 |
Loa Loa (eye worm) | cysteine protease | 0.0078 | 0.0414 | 0.5017 |
Onchocerca volvulus | 0.0105 | 0.0587 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Echinococcus granulosus | voltage gated hydrogen channel 1 | 0.0034 | 0.0123 | 0.0371 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.003 | 0.0101 | 0.1729 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0299 | 0.185 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0414 | 0.5017 |
Schistosoma mansoni | transient receptor potential channel | 0.0034 | 0.0123 | 0.1017 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0034 | 0.0123 | 0.0371 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | Potassium voltage gated channel protein Shaw | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0035 | 0.0129 | 0.1069 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0105 | 0.0587 | 0.1459 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0078 | 0.0414 | 0.1253 |
Brugia malayi | Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog | 0.0034 | 0.0123 | 0.1487 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Brugia malayi | cation channel family protein | 0.0034 | 0.0123 | 0.1487 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Echinococcus granulosus | 5'partial|3'partial|mitogen activated protein kinase kinase kinase | 0.0052 | 0.024 | 0.0726 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.004 | 0.0166 | 0.053 |
Echinococcus multilocularis | ryanodine receptor 44f | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0052 | 0.024 | 0.0726 |
Echinococcus multilocularis | calcium activated potassium channel | 0.0034 | 0.0123 | 0.0371 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0299 | 0.185 | 1 |
Plasmodium vivax | vivapain-2 | 0.0078 | 0.0414 | 0.0345 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0034 | 0.0123 | 0.1017 |
Echinococcus multilocularis | shaker cognate | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0034 | 0.0123 | 0.1017 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0035 | 0.0129 | 0.039 |
Echinococcus multilocularis | geminin | 0.02 | 0.1206 | 0.3653 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0078 | 0.0414 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0035 | 0.0129 | 0.1563 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0034 | 0.0123 | 0.0371 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0105 | 0.0587 | 0.1776 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0053 | 0.0245 | 0.0124 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0034 | 0.0123 | 0.0371 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0105 | 0.0587 | 0.2895 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0414 | 0.5017 |
Brugia malayi | Papain family cysteine protease containing protein | 0.004 | 0.0166 | 0.2013 |
Onchocerca volvulus | Cathepsin L homolog | 0.0078 | 0.0414 | 0.7056 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0414 | 0.0916 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Echinococcus multilocularis | potassium voltage gated channel subfamily KQT | 0.0034 | 0.0123 | 0.0371 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.0166 | 0.0251 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0026 | 0.0072 | 0.0869 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0231 | 0.1917 |
Leishmania major | cathepsin L-like protease | 0.0299 | 0.185 | 0.5432 |
Brugia malayi | Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit | 0.0034 | 0.0123 | 0.1487 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0299 | 0.185 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0034 | 0.0123 | 0.0371 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Plasmodium vivax | vivapain-1 | 0.004 | 0.0166 | 0.0095 |
Brugia malayi | cation channel family protein | 0.0034 | 0.0123 | 0.1487 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.0105 | 0.0587 | 0.0519 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | dihydropteridine reductase | 0.0105 | 0.0587 | 0.4862 |
Schistosoma mansoni | voltage-dependent calcium channel | 0.0034 | 0.0123 | 0.1017 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0105 | 0.0587 | 0.047 |
Schistosoma mansoni | ryanodine receptor related | 0.0034 | 0.0123 | 0.1017 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0034 | 0.0123 | 0.0371 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.0166 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Echinococcus multilocularis | cathepsin L | 0.004 | 0.0166 | 0.0503 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0235 | 0.1433 | 0.7656 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0034 | 0.0123 | 0.0371 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0091 | 0.0753 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | voltage-gated cation channel | 0.0034 | 0.0123 | 0.1017 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0129 | 0.1563 |
Brugia malayi | Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog | 0.0034 | 0.0123 | 0.1487 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.0053 | 0.0248 | 0.075 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Brugia malayi | Cytochrome P450 family protein | 0.0053 | 0.0249 | 0.3021 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0231 | 0.07 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.004 | 0.0166 | 0.053 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0231 | 0.1917 |
Echinococcus multilocularis | potassium voltage gated channel subfamily A | 0.0034 | 0.0123 | 0.0371 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0035 | 0.0129 | 0.039 |
Echinococcus granulosus | potassium large conductance calcium activated | 0.0034 | 0.0123 | 0.0371 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0034 | 0.0123 | 0.1017 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.1487 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0414 | 0.0295 |
Brugia malayi | Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit | 0.0034 | 0.0123 | 0.1487 |
Onchocerca volvulus | 0.0053 | 0.0245 | 0.4175 | |
Brugia malayi | Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog | 0.0034 | 0.0123 | 0.1487 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0414 | 0.5017 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0149 | 0.1807 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0078 | 0.0414 | 0.0252 |
Schistosoma mansoni | hypothetical protein | 0.02 | 0.1206 | 1 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0414 | 0.0916 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0414 | 0.0916 |
Loa Loa (eye worm) | voltage-dependent calcium channel | 0.0034 | 0.0123 | 0.1487 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0105 | 0.0587 | 0.711 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0026 | 0.0072 | 0.0869 |
Loa Loa (eye worm) | mbt repeat family protein | 0.003 | 0.0101 | 0.1229 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.155 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0078 | 0.0414 | 0.1253 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0231 | 0.07 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0414 | 0.5017 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0052 | 0.024 | 0.0726 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0034 | 0.0123 | 0.0371 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.0105 | 0.0587 | 0.0428 |
Echinococcus granulosus | potassium voltage gated channel subfamily A | 0.0034 | 0.0123 | 0.0371 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0105 | 0.0587 | 0.1459 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 188 uM | Cytotoxicity against human HEPG2 cells after 24 hrs by MTT assay | ChEMBL. | 18586491 |
IC50 (functional) | >= 250 uM | Cytotoxicity against human WRL68 cells after 24 hrs by MTT assay | ChEMBL. | 18586491 |
IC50 (functional) | >= 250 uM | Cytotoxicity against human CaCO2 cells after 24 hrs by MTT assay | ChEMBL. | 18586491 |
IC50 (functional) | >= 250 uM | Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay | ChEMBL. | 18586491 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.