Detailed information for compound 984994

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 405.071 | Formula: C15H12BrCl2NO3
  • H donors: 1 H acceptors: 1 LogP: 4.65 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(Br)ccc1NC(=O)c1cc(Cl)cc(c1OC)Cl
  • InChi: 1S/C15H12BrCl2NO3/c1-21-13-5-8(16)3-4-12(13)19-15(20)10-6-9(17)7-11(18)14(10)22-2/h3-7H,1-2H3,(H,19,20)
  • InChiKey: AYSYKNHFAYPRTA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.4189 0.473
Loa Loa (eye worm) neuropeptide F receptor 0.0076 0.4189 0.473
Brugia malayi hypothetical protein 0.0076 0.4189 0.473
Brugia malayi Serotonin receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) CYP4Cod1 0.0075 0.4133 0.4668
Echinococcus multilocularis g protein coupled receptor 0.0076 0.4189 0.473
Echinococcus granulosus biogenic amine 5HT receptor 0.0076 0.4189 0.473
Echinococcus granulosus neuropeptide Y receptor 0.0076 0.4189 0.473
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0076 0.4189 0.473
Echinococcus granulosus neuropeptide Y receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) neuropeptide F receptor 0.0076 0.4189 0.473
Echinococcus granulosus orexin receptor type 2 0.0076 0.4189 0.473
Onchocerca volvulus 0.0076 0.4189 0.5
Brugia malayi Cytochrome P450 family protein 0.0047 0.1172 0.1324
Echinococcus multilocularis g-protein coupled receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Brugia malayi cytochrome P450 0.0047 0.1172 0.1324
Brugia malayi GnHR receptor homolog 0.0076 0.4189 0.473
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0076 0.4189 0.473
Echinococcus multilocularis fmrfamide receptor 0.0076 0.4189 0.473
Echinococcus granulosus biogenic amine 5HT receptor 0.0076 0.4189 0.473
Brugia malayi hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus granulosus fmrfamide receptor 0.0076 0.4189 0.473
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0076 0.4189 0.473
Echinococcus multilocularis G protein coupled receptor 139 0.0076 0.4189 0.473
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0047 0.1172 0.5
Echinococcus granulosus 7tm_1 domain containing protein 0.0076 0.4189 0.473
Brugia malayi hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Brugia malayi Tachykinin-like peptides receptor 99D 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0121 0.8855 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus multilocularis dro:myosuppressin receptor 0.0076 0.4189 0.473
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0076 0.4189 0.4189
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0047 0.1172 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.4189 0.4189
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0047 0.1172 0.5
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni amine GPCR 0.0076 0.4189 0.4189
Schistosoma mansoni cytochrome P450 0.0047 0.1172 0.1172
Brugia malayi Serotonin receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus granulosus neuropeptide receptor 0.0076 0.4189 0.473
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0076 0.4189 0.5
Onchocerca volvulus 0.0076 0.4189 0.5
Echinococcus granulosus peptide allatostatin:somatostatin 0.0076 0.4189 0.473
Loa Loa (eye worm) G-protein coupled receptor 0.0076 0.4189 0.473
Brugia malayi Dopamine receptor 0.0076 0.4189 0.473
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.4189 0.473
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.4189 0.4189
Echinococcus granulosus tm gpcr rhodopsin 0.0076 0.4189 0.473
Echinococcus granulosus g protein coupled receptor 0.0076 0.4189 0.473
Schistosoma mansoni growth hormone secretagogue receptor 0.0076 0.4189 0.4189
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0047 0.1172 0.5
Schistosoma mansoni biogenic amine receptor 0.0076 0.4189 0.4189
Trypanosoma cruzi cytochrome P450, putative 0.0075 0.4133 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0076 0.4189 0.4189
Schistosoma mansoni neuropeptide receptor 0.0076 0.4189 0.4189
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0076 0.4189 0.473
Brugia malayi ORL1-like opioid receptor 0.0076 0.4189 0.473
Echinococcus multilocularis g protein coupled receptor 0.0076 0.4189 0.473
Onchocerca volvulus 0.0076 0.4189 0.5
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0076 0.4189 0.473
Echinococcus multilocularis fmrfamide receptor 0.0076 0.4189 0.473
Onchocerca volvulus 0.0076 0.4189 0.5
Echinococcus granulosus neuropeptide receptor 0.0076 0.4189 0.473
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0047 0.1172 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.4189 0.473
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0076 0.4189 0.473
Schistosoma mansoni amine GPCR 0.0076 0.4189 0.4189
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus multilocularis neuropeptide receptor A26 0.0076 0.4189 0.473
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0047 0.1172 0.5
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0076 0.4189 0.473
Schistosoma mansoni amine GPCR 0.0076 0.4189 0.4189
Echinococcus granulosus neuropeptide FF receptor 2 0.0076 0.4189 0.473
Schistosoma mansoni opsin-like receptor 0.0076 0.4189 0.4189
Echinococcus granulosus allatostatin A receptor 0.0076 0.4189 0.473
Onchocerca volvulus Neuropeptide F receptor homolog 0.0076 0.4189 0.5
Onchocerca volvulus 0.0076 0.4189 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni histamine h1 receptor 0.0076 0.4189 0.4189
Echinococcus granulosus G protein coupled receptor 139 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0105 0.7208 0.8141
Brugia malayi Cytochrome P450 family protein 0.0075 0.4133 0.4668
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0075 0.4133 1
Brugia malayi hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) cytochrome P450 family protein 0.0109 0.7621 0.8607
Onchocerca volvulus 0.0076 0.4189 0.5
Schistosoma mansoni opsin-like receptor 0.0076 0.4189 0.4189
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.4189 0.4189
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0047 0.1172 0.5
Brugia malayi G-protein coupled receptor 0.0076 0.4189 0.473
Echinococcus multilocularis neuropeptides capa receptor 0.0076 0.4189 0.473
Brugia malayi putative neuropeptide receptor 0.0076 0.4189 0.473
Mycobacterium leprae putative cytochrome p450 0.0047 0.1172 0.5
Echinococcus granulosus dro:myosuppressin receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.4189 0.473
Echinococcus multilocularis 0.0047 0.1172 0.1324
Echinococcus granulosus g protein coupled receptor 0.0076 0.4189 0.473
Schistosoma mansoni biogenic amine receptor 0.0076 0.4189 0.4189
Trypanosoma brucei cytochrome P450, putative 0.0075 0.4133 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.4189 0.4189
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.4189 0.473
Brugia malayi Dopamine receptor protein 2 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0076 0.4189 0.473
Mycobacterium leprae Conserved hypothetical protein 0.0047 0.1172 0.5
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Onchocerca volvulus 0.0076 0.4189 0.5
Echinococcus granulosus cytochrome P450 2K1 0.0047 0.1172 0.1324
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0047 0.1172 0.5
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0076 0.4189 0.473
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0076 0.4189 0.4189
Echinococcus multilocularis neuropeptides capa receptor 0.0076 0.4189 0.473
Echinococcus granulosus neuropeptides capa receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0121 0.8855 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.4189 0.473
Echinococcus multilocularis g protein coupled receptor 0.0076 0.4189 0.473
Brugia malayi hypothetical protein 0.0076 0.4189 0.473
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0076 0.4189 0.473
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0047 0.1172 0.5
Echinococcus multilocularis neuropeptide FF receptor 2 0.0076 0.4189 0.473
Echinococcus granulosus serotonin receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Toxoplasma gondii cytochrome p450 superfamily protein 0.0047 0.1172 0.5
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Brugia malayi follicle stimulating hormone receptor 0.0076 0.4189 0.473
Onchocerca volvulus 0.0076 0.4189 0.5
Echinococcus multilocularis allatostatin A receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) TYRA-2 protein 0.0076 0.4189 0.473
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0076 0.4189 0.473
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0047 0.1172 0.5
Echinococcus granulosus 7TM GPCR rhodopsin 0.0076 0.4189 0.473
Echinococcus granulosus tm gpcr rhodopsin 0.0076 0.4189 0.473
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.4189 0.473
Schistosoma mansoni neuropeptide receptor 0.0076 0.4189 0.4189
Schistosoma mansoni hypothetical protein 0.0047 0.1172 0.1172
Brugia malayi hypothetical protein 0.0076 0.4189 0.473
Onchocerca volvulus 0.0076 0.4189 0.5
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0047 0.1172 0.5
Echinococcus multilocularis G-protein coupled receptor, putative 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni opsin-like receptor 0.0076 0.4189 0.4189
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.4189 0.4189
Brugia malayi larval opioid receptor 0.0076 0.4189 0.473
Schistosoma mansoni voltage-gated potassium channel 0.0132 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0076 0.4189 0.473
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0076 0.4189 0.473
Brugia malayi Dopamine receptor protein 1 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni neuropeptide receptor 0.0076 0.4189 0.4189
Brugia malayi hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.4189 0.4189
Schistosoma mansoni hypothetical protein 0.0076 0.4189 0.4189
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0076 0.4189 0.4189
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0076 0.4189 0.473
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0047 0.1172 0.5
Schistosoma mansoni neuropeptide f receptor 76f 0.0076 0.4189 0.4189
Onchocerca volvulus 0.0076 0.4189 0.5
Schistosoma mansoni biogenic amine (5HT) receptor 0.0076 0.4189 0.4189
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) cytochrome P450 0.0047 0.1172 0.1324
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus multilocularis neuropeptide s receptor 0.0076 0.4189 0.473
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.4189 0.473
Brugia malayi Cytochrome P450 family protein 0.0075 0.4133 0.4668
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0076 0.4189 0.473
Echinococcus granulosus g-protein coupled receptor 0.0076 0.4189 0.473
Onchocerca volvulus 0.0076 0.4189 0.5
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0047 0.1172 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.4189 0.473
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0047 0.1172 0.5
Echinococcus multilocularis orexin receptor type 2 0.0076 0.4189 0.473
Loa Loa (eye worm) cytochrome P450 family protein 0.0075 0.4133 0.4668
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus multilocularis neuropeptide Y receptor 0.0076 0.4189 0.473
Brugia malayi G protein-coupled receptor 0.0076 0.4189 0.473
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0047 0.1172 0.5
Schistosoma mansoni biogenic amine receptor 0.0076 0.4189 0.4189
Brugia malayi hypothetical protein 0.0076 0.4189 0.473
Brugia malayi hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni myosin xvIII 0.0076 0.4189 0.4189
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.4189 0.4189
Schistosoma mansoni hypothetical protein 0.0076 0.4189 0.4189
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0121 0.8855 1
Echinococcus multilocularis somatostatin receptor 0.0076 0.4189 0.473
Onchocerca volvulus 0.0076 0.4189 0.5
Brugia malayi G protein-coupled receptor F59B2.13 0.0076 0.4189 0.473
Echinococcus granulosus somatostatin receptor 0.0076 0.4189 0.473
Brugia malayi Melatonin receptor type 1A 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0076 0.4189 0.473
Brugia malayi putative neuropeptide receptor NPR1 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Brugia malayi G-protein coupled receptor 0.0076 0.4189 0.473
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0113 0.8035 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.4189 0.473
Brugia malayi neuropeptide F receptor 0.0076 0.4189 0.473
Echinococcus granulosus hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0076 0.4189 0.473
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0047 0.1172 0.5
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0076 0.4189 0.473
Echinococcus multilocularis serotonin receptor 0.0076 0.4189 0.473
Onchocerca volvulus 0.0076 0.4189 0.5
Schistosoma mansoni adenoreceptor 0.0076 0.4189 0.4189
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.4189 0.4189
Brugia malayi AKH receptor 0.0076 0.4189 0.473
Echinococcus multilocularis neuropeptide receptor 0.0076 0.4189 0.473
Echinococcus multilocularis neuropeptide receptor 0.0076 0.4189 0.473
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0076 0.4189 0.4189
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni alpha-1 adrenergic receptor 0.0076 0.4189 0.4189
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0047 0.1172 0.5
Schistosoma mansoni neuropeptide receptor 0.0076 0.4189 0.4189
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0076 0.4189 0.4189
Onchocerca volvulus 0.0076 0.4189 0.5
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0047 0.1172 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.4189 0.4189
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.4189 0.4189
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0076 0.4189 0.4189
Brugia malayi hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni neuropeptide F-like receptor 0.0076 0.4189 0.4189
Onchocerca volvulus 0.0076 0.4189 0.5
Echinococcus multilocularis sex peptide receptor 0.0076 0.4189 0.473
Schistosoma mansoni biogenic amine (5HT) receptor 0.0076 0.4189 0.4189
Onchocerca volvulus 0.0076 0.4189 0.5
Loa Loa (eye worm) melatonin receptor type 1A 0.0076 0.4189 0.473
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.4189 0.473
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0076 0.4189 0.473
Schistosoma mansoni amine GPCR 0.0076 0.4189 0.4189
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0121 0.8855 1
Echinococcus granulosus neuropeptide s receptor 0.0076 0.4189 0.473
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0076 0.4189 0.473
Echinococcus granulosus tm gpcr rhodopsin 0.0076 0.4189 0.473
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0047 0.1172 0.5
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0076 0.4189 0.4189
Trypanosoma cruzi cytochrome P450, putative 0.0075 0.4133 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Schistosoma mansoni neuropeptide F-like receptor 0.0076 0.4189 0.4189
Echinococcus multilocularis serotonin receptor 0.0076 0.4189 0.473
Echinococcus granulosus alpha 1A adrenergic receptor 0.0076 0.4189 0.473
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.4189 0.4189
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0076 0.4189 0.473
Echinococcus granulosus sex peptide receptor 0.0076 0.4189 0.473
Echinococcus granulosus g protein coupled receptor 0.0076 0.4189 0.473
Schistosoma mansoni amine GPCR 0.0076 0.4189 0.4189
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0076 0.4189 0.473
Schistosoma mansoni hypothetical protein 0.0076 0.4189 0.4189
Brugia malayi neuropeptide F receptor 0.0076 0.4189 0.473
Brugia malayi Cytochrome P450 family protein 0.0109 0.7621 0.8607
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0076 0.4189 0.473
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.4189 0.473
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0113 0.8035 0.5
Loa Loa (eye worm) hypothetical protein 0.0076 0.4189 0.473
Loa Loa (eye worm) cytochrome P450 family protein 0.0075 0.4133 0.4668
Echinococcus granulosus neuropeptides capa receptor 0.0076 0.4189 0.473
Schistosoma mansoni hypothetical protein 0.0076 0.4189 0.4189
Echinococcus granulosus neuropeptide receptor A26 0.0076 0.4189 0.473
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0047 0.1172 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.4189 0.4189
Brugia malayi sulfakinin receptor protein 0.0076 0.4189 0.473
Brugia malayi RE15519p 0.0076 0.4189 0.473
Loa Loa (eye worm) G-protein coupled receptor 0.0076 0.4189 0.473
Onchocerca volvulus 0.0076 0.4189 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.4189 0.473
Echinococcus multilocularis neuropeptide Y receptor 0.0076 0.4189 0.473
Echinococcus granulosus tachykinin peptides receptor 99D 0.0076 0.4189 0.473
Leishmania major cytochrome p450-like protein 0.0075 0.4133 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.4189 0.473
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0076 0.4189 0.4189
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0076 0.4189 0.4189

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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