Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0001 | 0 | 0.5 | |
Echinococcus granulosus | kelch protein 12 | 0.0001 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Brugia malayi | Kelch motif family protein | 0.0001 | 0.0003 | 0.0007 |
Brugia malayi | hypothetical protein | 0.0111 | 0.3781 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.0001 | 0 | 0.5 | |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.3781 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0292 | 1 | 1 |
Echinococcus multilocularis | kelch protein 3 | 0.0001 | 0.0003 | 0.0003 |
Echinococcus granulosus | kelch protein 3 | 0.0001 | 0.0003 | 0.0003 |
Echinococcus granulosus | kelch protein 18 | 0.0001 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Echinococcus multilocularis | kelch protein 12 | 0.0001 | 0.0003 | 0.0003 |
Brugia malayi | BTB/POZ domain containing protein | 0.0001 | 0.0003 | 0.0007 |
Echinococcus multilocularis | kelch protein 18 | 0.0001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | Klhl5 protein | 0.0001 | 0.0003 | 1 |
Onchocerca volvulus | 0.0001 | 0 | 0.5 | |
Brugia malayi | Kelch-like protein X | 0.0001 | 0.0003 | 0.0007 |
Loa Loa (eye worm) | kelch domain-containing protein family protein | 0.0001 | 0.0003 | 1 |
Echinococcus multilocularis | kelch protein 10 | 0.0001 | 0.0003 | 0.0003 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.3781 | 0.5 |
Echinococcus granulosus | kelch protein 10 | 0.0001 | 0.0003 | 0.0003 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0291 | 0.9972 | 0.9972 |
Brugia malayi | Kelch motif family protein | 0.0001 | 0.0003 | 0.0007 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0111 | 0.3781 | 0.3781 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.0001 | 0 | 0.5 | |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.3781 | 0.5 |
Echinococcus multilocularis | ectoderm neural cortex protein 1 | 0.0001 | 0.0003 | 0.0003 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0111 | 0.3781 | 0.3781 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.3781 | 0.5 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0291 | 0.9972 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0111 | 0.3781 | 0.3792 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0291 | 0.9972 | 1 |
Echinococcus granulosus | ectoderm neural cortex protein 1 | 0.0001 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0111 | 0.3781 | 0.3781 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0291 | 0.9972 | 0.9972 |
Echinococcus granulosus | kelch ECH associated protein 1 | 0.0291 | 0.9972 | 1 |
Loa Loa (eye worm) | ring canal kelch protein | 0.0001 | 0.0003 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.