Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | fms-related tyrosine kinase 3 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1133 | 0.1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0079 | 0.0765 | 0.2714 |
Schistosoma mansoni | chromobox protein | 0.0141 | 0.2819 | 0.2712 |
Echinococcus granulosus | acetylcholinesterase | 0.0358 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0358 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1133 | 0.1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0358 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.3891 | 0.38 |
Echinococcus multilocularis | chromobox protein 1 | 0.0141 | 0.2819 | 0.2712 |
Echinococcus granulosus | chromobox protein 1 | 0.0141 | 0.2819 | 0.2712 |
Echinococcus granulosus | carboxylesterase 5A | 0.0358 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0061 | 0.0148 | 0.0524 |
Schistosoma mansoni | eyes absent homolog | 0.009 | 0.1133 | 0.1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0231 | 0.5777 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0061 | 0.0148 | 0.0524 |
Trichomonas vaginalis | chromobox protein, putative | 0.0085 | 0.0964 | 0.3419 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0079 | 0.0765 | 0.7562 |
Echinococcus granulosus | acetylcholinesterase | 0.0358 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0079 | 0.0765 | 0.2714 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0085 | 0.0964 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0141 | 0.2819 | 0.2712 |
Loa Loa (eye worm) | carboxylesterase | 0.0358 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.009 | 0.1133 | 0.1 |
Brugia malayi | Heterochromatin protein 1 | 0.0141 | 0.2819 | 0.2712 |
Brugia malayi | Carboxylesterase family protein | 0.0358 | 1 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0141 | 0.2819 | 0.2712 |
Loa Loa (eye worm) | hypothetical protein | 0.0358 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0358 | 1 | 1 |
Brugia malayi | chromobox protein homolog 3 | 0.0079 | 0.0765 | 0.0626 |
Echinococcus multilocularis | geminin | 0.0174 | 0.3891 | 0.38 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0358 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0.0199 | 0.0626 | |
Trichomonas vaginalis | chromobox protein, putative | 0.0141 | 0.2819 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0085 | 0.0964 | 0.3419 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0061 | 0.0148 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.3891 | 0.38 |
Trichomonas vaginalis | chromobox protein, putative | 0.0141 | 0.2819 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0141 | 0.2819 | 0.2712 |
Echinococcus granulosus | geminin | 0.0174 | 0.3891 | 0.38 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0765 | 0.0626 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0358 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0358 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0199 | 0.0052 |
Schistosoma mansoni | chromobox protein | 0.0141 | 0.2819 | 0.2712 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.