Detailed information for compound 988745

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 548.627 | Formula: C31H36N2O7
  • H donors: 1 H acceptors: 3 LogP: 5.53 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cc2cc(NC(=O)c3ccc(c(c3)CC=C(C)C)OC(=O)C)c(=O)oc2c(c1OC1CCN(CC1)C)C
  • InChi: 1S/C31H36N2O7/c1-18(2)7-8-21-15-22(9-10-26(21)38-20(4)34)30(35)32-25-16-23-17-27(37-6)29(19(3)28(23)40-31(25)36)39-24-11-13-33(5)14-12-24/h7,9-10,15-17,24H,8,11-14H2,1-6H3,(H,32,35)
  • InChiKey: FMYKRAFLJUUNIH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi sulfakinin receptor protein 0.0387 0.309 0.3725
Giardia lamblia Beta tubulin 0.0089 0.0569 0.1077
Echinococcus granulosus biogenic amine 5HT receptor 0.0179 0.1334 0.1334
Schistosoma mansoni nck2/grb4 0.0028 0.0058 0.0058
Onchocerca volvulus 0.0179 0.1334 0.5397
Loa Loa (eye worm) steroid hormone receptor 0.0025 0.0033 0.0039
Echinococcus granulosus NCK adaptor protein 0.0028 0.0058 0.0058
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0086 0.0547 0.0547
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Leishmania major beta tubulin 0.0089 0.0569 1
Brugia malayi GnHR receptor homolog 0.0179 0.1334 0.1608
Schistosoma mansoni tyrosine kinase 0.0139 0.0995 0.0995
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0056 0.0289 0.0289
Echinococcus granulosus alpha 1A adrenergic receptor 0.0179 0.1334 0.1334
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0167 0.1226 0.1478
Onchocerca volvulus 0.0051 0.0247 0.0999
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0056 0.0289 0.1081
Echinococcus granulosus orexin receptor type 2 0.0179 0.1334 0.1334
Leishmania major beta tubulin 0.0089 0.0569 1
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0176 0.1308 0.1308
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0179 0.1334 0.1334
Toxoplasma gondii subtilisin SUB7 0.0047 0.0214 0.0142
Mycobacterium leprae Possible secreted protease 0.0047 0.0214 0.5
Plasmodium falciparum subtilisin-like protease 3 0.0047 0.0214 0.0266
Echinococcus granulosus tyrosine protein kinase Src64B 0.0093 0.0602 0.0602
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0025 0.0033 0.0039
Echinococcus multilocularis SWI:SNF matrix associated 0.0043 0.0184 0.0184
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0117 0.0808 0.0974
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0025 0.0033 0.0039
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0179 0.1334 0.1608
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0093 0.0602 0.0602
Echinococcus granulosus tyrosine protein kinase Fyn 0.0093 0.0602 0.0602
Trichomonas vaginalis tubulin beta chain, putative 0.0089 0.0569 0.0791
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Brugia malayi Variant SH3 domain containing protein 0.0028 0.0058 0.007
Schistosoma mansoni amine GPCR 0.0179 0.1334 0.1334
Echinococcus granulosus 7TM GPCR rhodopsin 0.0179 0.1334 0.1334
Schistosoma mansoni biogenic amine (5HT) receptor 0.0179 0.1334 0.1334
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0025 0.0033 0.0039
Loa Loa (eye worm) hypothetical protein 0.0167 0.1226 0.1478
Brugia malayi Tubulin beta-1 chain 0.0089 0.0569 0.0686
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0033 0.0103 0.0103
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Chlamydia trachomatis DNA topoisomerase I 0.0043 0.0184 0.5
Leishmania major beta tubulin 0.0089 0.0569 1
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0062 0.0343 0.0328
Echinococcus multilocularis neuropeptide Y receptor 0.0179 0.1334 0.1334
Schistosoma mansoni tubulin subunit beta 0.0089 0.0569 0.0569
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Onchocerca volvulus 0.0179 0.1334 0.5397
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0214 0.0063
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Loa Loa (eye worm) hypothetical protein 0.0387 0.309 0.3725
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0032 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0023 0.0015 0.0015
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0033 0.0103 0.0103
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.018 0.1339 0.1614
Echinococcus multilocularis SWI:SNF matrix associated 0.0043 0.0184 0.0184
Loa Loa (eye worm) TK/ABL protein kinase 0.0221 0.1684 0.203
Trypanosoma brucei RNA helicase, putative 0.032 0.2524 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Trichomonas vaginalis tubulin gamma chain, putative 0.0089 0.0569 0.0791
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0047 0.0214 0.0214
Brugia malayi steroid hormone receptor 0.0025 0.0033 0.0039
Brugia malayi bZIP transcription factor family protein 0.0086 0.0547 0.0659
Brugia malayi G protein-coupled receptor 0.0179 0.1334 0.1608
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0025 0.0033 0.0039
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0179 0.1334 0.1334
Brugia malayi Tachykinin-like peptides receptor 99D 0.0179 0.1334 0.1608
Echinococcus multilocularis neuropeptide FF receptor 2 0.0179 0.1334 0.1334
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0314 0.2472 0.2472
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0056 0.0289 0.0349
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0179 0.1334 0.1334
Trypanosoma brucei beta tubulin 0.0089 0.0569 0.1537
Loa Loa (eye worm) SRC-1 0.0093 0.0602 0.0725
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0028 0.0058 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Echinococcus multilocularis serotonin receptor 0.0179 0.1334 0.1334
Schistosoma mansoni biogenic amine receptor 0.0179 0.1334 0.1334
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0079 0.0484 0.0484
Brugia malayi follicle stimulating hormone receptor 0.0179 0.1334 0.1608
Plasmodium vivax prenyltransferase alpha subunit, putative 0.018 0.1339 1
Leishmania major farnesyltransferase beta subunit 0.0056 0.0289 0.2258
Brugia malayi Dopamine receptor 0.0179 0.1334 0.1608
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0258 0.1995 0.1995
Leishmania major beta tubulin 0.0089 0.0569 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0179 0.1334 0.1608
Onchocerca volvulus Protein ultraspiracle homolog 0.0025 0.0033 0.0132
Loa Loa (eye worm) TK protein kinase 0.0064 0.0364 0.0439
Trypanosoma cruzi protein farnesyltransferase, putative 0.0056 0.0289 0.2117
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0116 0.0116
Brugia malayi Protein kinase domain containing protein 0.0101 0.0669 0.0807
Brugia malayi RE15519p 0.0179 0.1334 0.1608
Loa Loa (eye worm) tubulin beta-2A chain 0.0089 0.0569 0.0686
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Echinococcus granulosus g protein coupled receptor 0.0179 0.1334 0.1334
Echinococcus granulosus Tubulin beta 2C chain 0.0089 0.0569 0.0569
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Echinococcus multilocularis g protein coupled receptor 0.0179 0.1334 0.1334
Echinococcus multilocularis dro:myosuppressin receptor 0.0179 0.1334 0.1334
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0025 0.0033 0.0039
Loa Loa (eye worm) BEN-1 protein 0.0089 0.0569 0.0686
Leishmania major beta tubulin 0.0089 0.0569 1
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0086 0.0547 0.0547
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0179 0.1334 0.1334
Plasmodium falciparum tubulin beta chain 0.0089 0.0569 0.3338
Schistosoma mansoni protein kinase 0.0135 0.0957 0.0957
Echinococcus multilocularis beta tubulin 0.0089 0.0569 0.0569
Toxoplasma gondii subtilisin SUB6 0.0047 0.0214 0.0142
Echinococcus multilocularis NCK adaptor protein 0.0028 0.0058 0.0058
Onchocerca volvulus 0.0047 0.0214 0.0867
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.018 0.1339 0.1339
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0179 0.1334 0.1334
Trichomonas vaginalis deoxyribonuclease II precursor, putative 0.0073 0.044 0.0525
Echinococcus granulosus neuropeptide receptor 0.0179 0.1334 0.1334
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0033 0.0033
Brugia malayi hypothetical protein 0.0179 0.1334 0.1608
Brugia malayi Dopamine receptor protein 2 0.0179 0.1334 0.1608
Brugia malayi Variant SH3 domain containing protein 0.0028 0.0058 0.007
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0033 0.0033
Brugia malayi Steroid receptor seven-up type 2 0.0025 0.0033 0.0039
Schistosoma mansoni serine-type protease inhibitor 0.0464 0.3739 0.3739
Echinococcus multilocularis Tubulin beta 2C chain 0.0089 0.0569 0.0569
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1602 0.2908
Toxoplasma gondii beta-1 tubulin, putative 0.0089 0.0569 0.1786
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0056 0.0289 0.0217
Schistosoma mansoni neuropeptide receptor 0.0179 0.1334 0.1334
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0343 0.3635
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0179 0.1334 0.1334
Trypanosoma cruzi beta tubulin, putative 0.0089 0.0569 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0258 0.1995 0.3715
Echinococcus granulosus tyrosine protein kinase ABL1 0.0221 0.1684 0.1684
Brugia malayi nuclear hormone receptor 0.0025 0.0033 0.0039
Schistosoma mansoni biogenic amine (5HT) receptor 0.0179 0.1334 0.1334
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Trichomonas vaginalis tubulin alpha chain, putative 0.0089 0.0569 0.0791
Loa Loa (eye worm) tubulin beta chain 0.0089 0.0569 0.0686
Schistosoma mansoni hypothetical protein 0.0043 0.0184 0.0184
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Brugia malayi hypothetical protein 0.0179 0.1334 0.1608
Echinococcus granulosus serotonin receptor 0.0179 0.1334 0.1334
Schistosoma mansoni brg-1 associated factor 0.0043 0.0184 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1602 0.2908
Loa Loa (eye worm) hypothetical protein 0.0103 0.0686 0.0827
Brugia malayi Sex muscle abnormal protein 5 0.0028 0.0058 0.007
Echinococcus multilocularis G-protein coupled receptor, putative 0.0179 0.1334 0.1334
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0047 0.0214 0.5
Schistosoma mansoni amine GPCR 0.0179 0.1334 0.1334
Brugia malayi beta-tubulin, identical 0.0089 0.0569 0.0686
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0062 0.0343 0.3635
Entamoeba histolytica tubulin family protein 0.0089 0.0569 0.3706
Echinococcus multilocularis 0.0793 0.6515 0.6515
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0047 0.0214 1
Echinococcus multilocularis growth factor receptor bound protein 2 0.0028 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Loa Loa (eye worm) TK/EPH protein kinase 0.0164 0.1202 0.1448
Schistosoma mansoni ephrin receptor 0.013 0.0914 0.0914
Echinococcus multilocularis Tubulin beta 2C chain 0.0089 0.0569 0.0569
Brugia malayi hypothetical protein 0.0179 0.1334 0.1608
Brugia malayi Tyrosine-protein kinase abl-1 0.0124 0.087 0.1048
Brugia malayi putative neuropeptide receptor 0.0179 0.1334 0.1608
Echinococcus granulosus cpg binding protein 0.0029 0.0069 0.0069
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0093 0.0602 0.0602
Schistosoma mansoni thyroid hormone receptor 0.0025 0.0033 0.0033
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0056 0.0289 0.049
Schistosoma mansoni tubulin subunit beta 0.0089 0.0569 0.0569
Loa Loa (eye worm) latrophilin receptor protein 2 0.0064 0.0361 0.0435
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0056 0.0289 0.1417
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0089 0.0569 0.0569
Echinococcus granulosus ecdysone induced protein 78C 0.0025 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0179 0.1334 0.1608
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Schistosoma mansoni retinoic acid receptor RXR 0.0025 0.0033 0.0033
Brugia malayi brahma associated protein 60 kDa 0.0043 0.0184 0.0221
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0179 0.1334 0.1608
Echinococcus multilocularis membrane bound transcription factor site 1 0.0047 0.0214 0.0214
Brugia malayi neuroendocrine convertase 1 precursor 0.0641 0.5231 0.6305
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni hypothetical protein 0.0064 0.0361 0.0361
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0056 0.0289 0.0217
Schistosoma mansoni hypothetical protein 0.0179 0.1334 0.1334
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0047 0.0214 0.0214
Leishmania major beta tubulin 0.0089 0.0569 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0135 0.0957 0.0957
Echinococcus granulosus neuropeptides capa receptor 0.0179 0.1334 0.1334
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0025 0.0033 0.0039
Echinococcus granulosus neuropeptide Y receptor 0.0179 0.1334 0.1334
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0093 0.0602 0.0602
Brugia malayi hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0047 0.0214 0.0214
Onchocerca volvulus 0.0023 0.0015 0.0062
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0135 0.0957 0.0957
Loa Loa (eye worm) hypothetical protein 0.0314 0.2472 0.2979
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0018
Echinococcus granulosus growth factor receptor bound protein 2 0.0028 0.0058 0.0058
Toxoplasma gondii subtilisin SUB2 0.0047 0.0214 0.0142
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0062 0.0343 0.0559
Brugia malayi hypothetical protein 0.0179 0.1334 0.1608
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0057 0.0304 0.2532
Brugia malayi hypothetical protein 0.0068 0.0391 0.0471
Echinococcus granulosus Tubulin beta 2C chain 0.0089 0.0569 0.0569
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0062 0.0343 0.1383
Loa Loa (eye worm) hypothetical protein 0.0084 0.0527 0.0635
Toxoplasma gondii hypothetical protein 0.0062 0.0343 0.074
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni tubulin subunit beta 0.0089 0.0569 0.0569
Loa Loa (eye worm) G-protein coupled receptor 0.0179 0.1334 0.1608
Trichomonas vaginalis tubulin epsilon chain, putative 0.0089 0.0569 0.0791
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0047 0.0214 0.0258
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0179 0.1334 0.1608
Brugia malayi nuclear receptor NHR-88 0.0025 0.0033 0.0039
Onchocerca volvulus 0.0124 0.0869 0.3516
Loa Loa (eye worm) TYRA-2 protein 0.0179 0.1334 0.1608
Echinococcus multilocularis neuropeptides capa receptor 0.0179 0.1334 0.1334
Onchocerca volvulus 0.0179 0.1334 0.5397
Loa Loa (eye worm) proprotein convertase 2 0.0258 0.1995 0.2405
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0179 0.1334 0.1608
Onchocerca volvulus 0.0314 0.2472 1
Onchocerca volvulus 0.0179 0.1334 0.5397
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0211 0.1602 0.2908
Giardia lamblia High cysteine membrane protein Group 2 0.0363 0.2886 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1199 0.9935 0.9935
Echinococcus granulosus fmrfamide receptor 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0039
Echinococcus multilocularis g-protein coupled receptor 0.0179 0.1334 0.1334
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0025 0.0033 0.0033
Brugia malayi Subtilase family protein 0.0047 0.0214 0.0258
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0064 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0039
Echinococcus granulosus deoxyribonuclease ii 0.0073 0.044 0.044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.1334 0.1334
Echinococcus granulosus Tubulin beta 2C chain 0.0089 0.0569 0.0569
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0176 0.1308 0.1577
Echinococcus multilocularis MAM 0.0023 0.0015 0.0015
Brugia malayi celfurPC protein 0.0793 0.6515 0.7853
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1602 0.2908
Schistosoma mansoni cpg binding protein 0.0029 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0179 0.1334 0.1608
Echinococcus granulosus tyrosine protein kinase Fyn 0.0093 0.0602 0.0602
Leishmania major beta tubulin 0.0089 0.0569 1
Brugia malayi map kinase activated protein kinase protein 2 0.0176 0.1308 0.1577
Echinococcus granulosus Tubulin beta 2C chain 0.0089 0.0569 0.0569
Entamoeba histolytica tubulin family protein 0.0089 0.0569 0.3706
Echinococcus multilocularis tubulin subunit beta 0.0089 0.0569 0.0569
Leishmania major beta tubulin 0.0089 0.0569 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0025 0.0033 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1602 0.2908
Brugia malayi G protein-coupled receptor F59B2.13 0.0179 0.1334 0.1608
Schistosoma mansoni hypothetical protein 0.007 0.0411 0.0411
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0035 0.0119 0.0119
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0127 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0214 0.0063
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0025 0.0033 0.0033
Giardia lamblia Beta tubulin 0.0089 0.0569 0.1077
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0062 0.0343 0.3635
Onchocerca volvulus 0.0179 0.1334 0.5397
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0179 0.1334 0.1334
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0062 0.0343 0.1539
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0062 0.0343 0.1858
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.1334 0.1334
Echinococcus granulosus furin 0.1005 0.8296 0.8296
Echinococcus multilocularis ephrin type A receptor 4 A 0.013 0.0914 0.0914
Onchocerca volvulus 0.0043 0.0184 0.0743
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0028 0.0058 0.007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Loa Loa (eye worm) G-protein coupled receptor 0.0179 0.1334 0.1608
Schistosoma mansoni amine GPCR 0.0179 0.1334 0.1334
Trypanosoma brucei hypothetical protein, conserved 0.0062 0.0343 0.0559
Onchocerca volvulus 0.0179 0.1334 0.5397
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1602 0.2908
Brugia malayi hypothetical protein 0.0035 0.0116 0.014
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0221 0.1684 0.1684
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0101 0.0669 0.0807
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0033 0.0033
Schistosoma mansoni growth factor receptor-bound protein 0.0028 0.0058 0.0058
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Schistosoma mansoni hypothetical protein 0.0179 0.1334 0.1334
Echinococcus granulosus hypothetical protein 0.0179 0.1334 0.1334
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0055 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0214 0.0063
Schistosoma mansoni opsin-like receptor 0.0179 0.1334 0.1334
Brugia malayi Deoxyribonuclease II family protein 0.0073 0.044 0.053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0018
Brugia malayi Latrophilin receptor protein 2 0.0064 0.0361 0.0435
Loa Loa (eye worm) beta-tubulin 0.0089 0.0569 0.0686
Schistosoma mansoni cpg binding protein 0.0029 0.0069 0.0069
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0179 0.1334 0.1334
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0127 0.0127
Loa Loa (eye worm) TK/CSK protein kinase 0.0036 0.0127 0.0153
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0056 0.0289 0.0289
Loa Loa (eye worm) deoxyribonuclease II family protein 0.0073 0.044 0.053
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1602 0.2908
Onchocerca volvulus 0.0179 0.1334 0.5397
Loa Loa (eye worm) TK/ALK protein kinase 0.0028 0.0061 0.0073
Schistosoma mansoni hypothetical protein 0.0064 0.0361 0.0361
Echinococcus granulosus G protein coupled receptor 139 0.0179 0.1334 0.1334
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0062 0.0343 0.0343
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0033 0.0033
Echinococcus multilocularis neuropeptide receptor 0.0179 0.1334 0.1334
Echinococcus multilocularis tyrosine protein kinase Blk 0.0079 0.0484 0.0484
Loa Loa (eye worm) hypothetical protein 0.0082 0.0515 0.0621
Echinococcus granulosus beta tubulin 0.0089 0.0569 0.0569
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0033 0.0039
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0025 0.0033 0.0039
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0047 0.0214 0.5
Leishmania major beta tubulin 0.0089 0.0569 1
Loa Loa (eye worm) tubulin beta-4 chain 0.0089 0.0569 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1602 0.2908
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.1334 0.1334
Echinococcus multilocularis sex peptide receptor 0.0179 0.1334 0.1334
Schistosoma mansoni adenoreceptor 0.0179 0.1334 0.1334
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0033 0.0033
Toxoplasma gondii subtilisin SUB11 0.0047 0.0214 0.0142
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0167 0.1226 0.1478
Echinococcus granulosus tyrosine protein kinase csk 0.0036 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0179 0.1334 0.1334
Echinococcus multilocularis neuropeptide Y receptor 0.0179 0.1334 0.1334
Echinococcus granulosus tubulin subunit beta 0.0089 0.0569 0.0569
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0686 0.0827
Echinococcus granulosus jun protein 0.0086 0.0547 0.0547
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0621 0.5061 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0062 0.0343 0.0343
Schistosoma mansoni jun-related protein 0.007 0.0411 0.0411
Echinococcus multilocularis Tubulin beta 2C chain 0.0089 0.0569 0.0569
Echinococcus granulosus g protein coupled receptor 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0179 0.1334 0.1334
Schistosoma mansoni thyroid hormone receptor 0.0025 0.0033 0.0033
Echinococcus multilocularis thyroid hormone receptor alpha 0.0025 0.0033 0.0033
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0043 0.0184 0.0181
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0116 0.0116
Echinococcus granulosus tyrosine protein kinase Fyn 0.0093 0.0602 0.0602
Loa Loa (eye worm) SH2 domain-containing protein 0.0045 0.0202 0.0243
Schistosoma mansoni tyrosine kinase 0.0093 0.0602 0.0602
Echinococcus granulosus biogenic amine 5HT receptor 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni neuropeptide receptor 0.0179 0.1334 0.1334
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0043 0.0184 0.0184
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0047 0.0214 0.0214
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0101 0.0669 0.0807
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0101 0.0669 0.0669
Echinococcus multilocularis tyrosine protein kinase HCK 0.0064 0.0364 0.0364
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0621 0.5061 0.5061
Echinococcus granulosus tubulin beta 1 chain 0.0089 0.0569 0.0569
Leishmania major beta tubulin 0.0089 0.0569 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0179 0.1334 0.1334
Plasmodium vivax subtilisin-like protease 2, putative 0.0047 0.0214 0.0442
Echinococcus granulosus Furin 1 0.0258 0.1995 0.1995
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni neuropeptide receptor 0.0179 0.1334 0.1334
Trypanosoma brucei beta tubulin 0.0089 0.0569 0.1537
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0062 0.0343 0.0343
Brugia malayi ORL1-like opioid receptor 0.0179 0.1334 0.1608
Leishmania major beta tubulin 0.0089 0.0569 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0025 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0047 0.0214 0.0258
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0057 0.0304 0.0389
Schistosoma mansoni site-1 peptidase (S08 family) 0.0047 0.0214 0.0214
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0039
Echinococcus multilocularis GPCR, family 2 0.0064 0.0361 0.0361
Brugia malayi neuropeptide F receptor 0.0179 0.1334 0.1608
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0179 0.1334 0.1334
Echinococcus granulosus sex peptide receptor 0.0179 0.1334 0.1334
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Schistosoma mansoni adapter molecule crk 0.0028 0.0058 0.0058
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0179 0.1334 0.1608
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0073 0.0439 0.0439
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0179 0.1334 0.1334
Schistosoma mansoni amine GPCR 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Toxoplasma gondii subtilisin SUB9 0.0047 0.0214 0.0142
Echinococcus multilocularis c src tyrosine kinase 0.0064 0.0364 0.0364
Toxoplasma gondii subtilisin SUB10 0.0047 0.0214 0.0142
Schistosoma mansoni protein kinase 0.0135 0.0957 0.0957
Echinococcus granulosus tyrosine protein kinase Blk 0.0079 0.0484 0.0484
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Brugia malayi neuropeptide F receptor 0.0179 0.1334 0.1608
Echinococcus granulosus membrane bound transcription factor site 1 0.0047 0.0214 0.0214
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Echinococcus granulosus g-protein coupled receptor 0.0179 0.1334 0.1334
Schistosoma mansoni hypothetical protein 0.0179 0.1334 0.1334
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0025 0.0033 0.0039
Echinococcus granulosus epidermal growth factor receptor 0.0139 0.0995 0.0995
Echinococcus granulosus 7tm_1 domain containing protein 0.0179 0.1334 0.1334
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0343 0.3635
Loa Loa (eye worm) subtilase 0.0047 0.0214 0.0258
Toxoplasma gondii PAN domain-containing protein 0.0299 0.2342 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0025 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0043 0.0184 0.0184
Brugia malayi Dopamine receptor protein 1 0.0179 0.1334 0.1608
Echinococcus multilocularis beta tubulin 0.0089 0.0569 0.0569
Loa Loa (eye worm) neuropeptide F receptor 0.0179 0.1334 0.1608
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.1334 0.1334
Onchocerca volvulus 0.0068 0.0391 0.1581
Echinococcus multilocularis Tubulin beta 2C chain 0.0089 0.0569 0.0569
Trichomonas vaginalis AGC family protein kinase 0.0101 0.0669 0.0996
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0047 0.0214 0.0258
Leishmania major beta tubulin 0.0089 0.0569 1
Onchocerca volvulus 0.0179 0.1334 0.5397
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0025 0.0033 0.0132
Echinococcus granulosus SWI:SNF matrix associated 0.0043 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0029 0.0062 0.0075
Loa Loa (eye worm) BEN-1 protein 0.0089 0.0569 0.0686
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0064 0.0361 0.0435
Brugia malayi putative neuropeptide receptor NPR1 0.0179 0.1334 0.1608
Echinococcus granulosus beta tubulin 0.0089 0.0569 0.0569
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.018 0.1339 0.2368
Brugia malayi endoprotease bli-4 precursor 0.1005 0.8296 1
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0062 0.0343 0.0559
Echinococcus granulosus FTZ F1 alpha 0.0025 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0064 0.0361 0.0361
Schistosoma mansoni hypothetical protein 0.0035 0.0116 0.0116
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0025 0.0033 0.0033
Echinococcus multilocularis neuropeptide receptor A26 0.0675 0.5519 0.5519
Leishmania major subtilisin-like serine peptidase 0.0047 0.0214 0.0179
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Brugia malayi hypothetical protein 0.0023 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0361 0.0435
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0056 0.0289 0.0217
Echinococcus multilocularis Tubulin beta 2C chain 0.0089 0.0569 0.0569
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0062 0.0343 0.3635
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.1334 0.1334
Schistosoma mansoni hypothetical protein 0.0211 0.1602 0.1602
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0211 0.1602 0.2908
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0064 0.0361 0.0361
Schistosoma mansoni opsin-like receptor 0.0179 0.1334 0.1334
Echinococcus granulosus neuropeptide FF receptor 2 0.0179 0.1334 0.1334
Schistosoma mansoni hypothetical protein 0.0064 0.0361 0.0361
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0093 0.0602 0.0602
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0063 0.0354 0.0427
Trichomonas vaginalis tubulin, putative 0.0089 0.0569 0.0791
Brugia malayi brahma associated protein 60 kDa 0.0043 0.0184 0.0221
Trichomonas vaginalis AGC family protein kinase 0.0101 0.0669 0.0996
Schistosoma mansoni RAR-like nuclear receptor 0.0025 0.0033 0.0033
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.018 0.1339 0.1614
Echinococcus granulosus ephrin type A receptor 4 A 0.013 0.0914 0.0914
Loa Loa (eye worm) TK/EGFR protein kinase 0.0139 0.0995 0.1199
Echinococcus granulosus neuropeptide receptor A26 0.0675 0.5519 0.5519
Echinococcus multilocularis G protein coupled receptor 139 0.0179 0.1334 0.1334
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.018 0.1339 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0621 0.5061 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.018 0.1339 0.1614
Echinococcus granulosus neuropeptide receptor 0.0179 0.1334 0.1334
Brugia malayi phosphoinositide-dependent protein kinase I 0.0101 0.0669 0.0807
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0179 0.1334 0.1334
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0179 0.1334 0.1608
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0025 0.0033 0.0039
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0039
Giardia lamblia Rab geranylgeranyltransferase 0.018 0.1339 0.4041
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0258 0.1995 0.3715
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Echinococcus multilocularis tubulin beta 1 chain 0.0089 0.0569 0.0569
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0127 0.0127
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.018 0.1339 0.2368
Onchocerca volvulus 0.0179 0.1334 0.5397
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Brugia malayi Serotonin receptor 0.0179 0.1334 0.1608
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0025 0.0033 0.0039
Schistosoma mansoni myosin xvIII 0.0179 0.1334 0.1334
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0179 0.1334 0.1334
Trypanosoma cruzi lanosterol synthase, putative 0.0061 0.0335 0.34
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Onchocerca volvulus Bile acid receptor homolog 0.0025 0.0033 0.0132
Echinococcus granulosus somatostatin receptor 0.0179 0.1334 0.1334
Echinococcus multilocularis neuropeptides capa receptor 0.0179 0.1334 0.1334
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0179 0.1334 0.1608
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Schistosoma mansoni hypothetical protein 0.0179 0.1334 0.1334
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0025 0.0033 0.0039
Schistosoma mansoni steroid hormone receptor ad4bp 0.0025 0.0033 0.0033
Schistosoma mansoni growth hormone secretagogue receptor 0.0179 0.1334 0.1334
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0028 0.0058 0.007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0179 0.1334 0.5397
Echinococcus multilocularis fmrfamide receptor 0.0179 0.1334 0.1334
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0032 0.009 0.009
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0062 0.0343 0.0414
Plasmodium vivax subtilisin-like protease 1 0.0047 0.0214 0.0442
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0179 0.1334 0.1334
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Schistosoma mansoni septate junction protein 0.0027 0.0052 0.0052
Echinococcus granulosus g protein coupled receptor 0.0179 0.1334 0.1334
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.018 0.1339 0.1339
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0025 0.0033 0.0039
Chlamydia trachomatis SWIB complex protein 0.0043 0.0184 0.5
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0025 0.0033 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0025 0.0033 0.0039
Giardia lamblia Rab geranylgeranyltransferase 0.0062 0.0343 0.0207
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0039
Schistosoma mansoni deoxyribonuclease II-related 0.0073 0.044 0.044
Echinococcus granulosus tm gpcr rhodopsin 0.0179 0.1334 0.1334
Echinococcus granulosus c src tyrosine kinase 0.0064 0.0364 0.0364
Schistosoma mansoni tyrosine kinase 0.0033 0.0103 0.0103
Echinococcus granulosus neuroendocrine convertase 2 0.0641 0.5231 0.5231
Schistosoma mansoni serine-type protease inhibitor 0.0464 0.3739 0.3739
Giardia lamblia Furin precursor putative serine protease 0.0211 0.1602 0.5054
Loa Loa (eye worm) hypothetical protein 0.0028 0.0058 0.007
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Plasmodium falciparum subtilisin-like protease 1 0.0047 0.0214 0.0266
Onchocerca volvulus Neuropeptide F receptor homolog 0.0179 0.1334 0.5397
Toxoplasma gondii subtilisin SUB12 0.0066 0.0377 0.0894
Leishmania major beta tubulin 0.0089 0.0569 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0179 0.1334 0.1334
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0062 0.0343 0.0414
Brugia malayi hypothetical protein 0.0387 0.309 0.3725
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0056 0.0289 0.0217
Brugia malayi hypothetical protein 0.0179 0.1334 0.1608
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0101 0.0669 0.0669
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0039
Echinococcus multilocularis Furin 1 0.0258 0.1995 0.1995
Echinococcus multilocularis ecdysone induced protein 78C 0.0025 0.0033 0.0033
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0025 0.0033 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0025 0.0033 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0214 0.0063
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0056 0.0289 0.0916
Loa Loa (eye worm) tubulin beta-1 chain 0.0089 0.0569 0.0686
Echinococcus multilocularis cpg binding protein 0.0029 0.0069 0.0069
Echinococcus multilocularis jun protein 0.0086 0.0547 0.0547
Onchocerca volvulus 0.0179 0.1334 0.5397
Onchocerca volvulus 0.0075 0.0455 0.184
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0176 0.1308 0.1308
Echinococcus granulosus MAM 0.0023 0.0015 0.0015
Schistosoma mansoni growth factor receptor-bound protein 0.0028 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Toxoplasma gondii subtilisin SUB8 0.0047 0.0214 0.0142
Brugia malayi G-protein coupled receptor 0.0179 0.1334 0.1608
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Echinococcus granulosus Tubulin beta 2C chain 0.0089 0.0569 0.0569
Leishmania major beta tubulin 0.0089 0.0569 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0179 0.1334 0.1334
Loa Loa (eye worm) neuropeptide F receptor 0.0179 0.1334 0.1608
Echinococcus granulosus tyrosine protein kinase Lyn 0.0094 0.0616 0.0616
Brugia malayi CXXC zinc finger family protein 0.0028 0.0055 0.0067
Schistosoma mansoni biogenic amine receptor 0.0179 0.1334 0.1334
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0056 0.0289 0.0325
Loa Loa (eye worm) endoprotease bli-4 0.1005 0.8296 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0079 0.0484 0.0484
Echinococcus granulosus tm gpcr rhodopsin 0.1199 0.9935 0.9935
Onchocerca volvulus 0.0179 0.1334 0.5397
Toxoplasma gondii beta tubulin 0.0089 0.0569 0.1786
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0025 0.0033 0.0033
Trichomonas vaginalis deoxyribonuclease II, putative 0.0073 0.044 0.0525
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0043 0.0184 0.0184
Schistosoma mansoni tubulin subunit beta 0.0089 0.0569 0.0569
Schistosoma mansoni hypothetical protein 0.032 0.2524 0.2524
Loa Loa (eye worm) brahma associated protein 0.0043 0.0184 0.0221
Leishmania major beta tubulin 0.0089 0.0569 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.1308 0.1308
Echinococcus multilocularis tyrosine protein kinase Abl 0.011 0.0753 0.0753
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1602 0.2908
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0047 0.0214 1
Schistosoma mansoni tubulin subunit beta 0.0089 0.0569 0.0569
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0025 0.0033 0.0039
Echinococcus granulosus tyrosine protein kinase Src42A 0.0073 0.0439 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1602 0.2908
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0117 0.0808 0.0974
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0093 0.0602 0.0602
Loa Loa (eye worm) melatonin receptor type 1A 0.0179 0.1334 0.1608
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0621 0.5061 0.5061
Onchocerca volvulus 0.0179 0.1334 0.5397
Schistosoma mansoni alpha-1 adrenergic receptor 0.0179 0.1334 0.1334
Toxoplasma gondii beta-tubulin, putative 0.0089 0.0569 0.1786
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1602 0.2908
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Echinococcus granulosus tachykinin peptides receptor 99D 0.0479 0.3858 0.3858
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0127 0.0127
Brugia malayi SH2 domain containing protein 0.0051 0.0247 0.0298
Toxoplasma gondii subtilisin SUB4 0.0047 0.0214 0.0142
Toxoplasma gondii hypothetical protein 0.0118 0.0816 0.293
Schistosoma mansoni protein kinase 0.0135 0.0957 0.0957
Echinococcus multilocularis orexin receptor type 2 0.0179 0.1334 0.1334
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0064 0.0361 0.0361
Echinococcus granulosus tubulin beta 4A class IVa 0.0089 0.0569 0.0569
Schistosoma mansoni coup transcription factor 0.0025 0.0033 0.0033
Trypanosoma cruzi protein farnesyltransferase, putative 0.0056 0.0289 0.2117
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0062 0.0343 0.3749
Trypanosoma cruzi lanosterol synthase, putative 0.0061 0.0335 0.34
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0062 0.0343 0.0559
Schistosoma mansoni hypothetical protein 0.0043 0.0184 0.0184
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0061 0.0335 1
Brugia malayi ecdysteroid receptor 0.0025 0.0033 0.0039
Echinococcus granulosus GPCR family 2 0.0064 0.0361 0.0361
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0025 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0062 0.0343 0.0343
Brugia malayi hypothetical protein 0.0179 0.1334 0.1608
Brugia malayi ephrin receptor 1 precursor 0.0064 0.036 0.0434
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Plasmodium vivax subtilisin-like serine protease, putative 0.0047 0.0214 0.0442
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0093 0.0602 0.0602
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0056 0.0289 0.0217
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0093 0.0602 0.0602
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0093 0.0602 0.0602
Onchocerca volvulus 0.0028 0.0055 0.0224
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.1334 0.1334
Brugia malayi Furin-like cysteine rich region family protein 0.0139 0.0995 0.1199
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0033 0.0033
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0118 0.0816 0.1297
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0043 0.0184 0.0221
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0179 0.1334 0.1334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.1334 0.1334
Echinococcus multilocularis neuropeptide receptor 0.0179 0.1334 0.1334
Schistosoma mansoni opsin-like receptor 0.0179 0.1334 0.1334
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0025 0.0033 0.0033
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0179 0.1334 0.1334
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0057 0.0304 0.2532
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0258 0.1995 0.3715
Loa Loa (eye worm) hypothetical protein 0.0383 0.3056 0.3684
Trypanosoma brucei beta tubulin 0.0089 0.0569 0.1537
Echinococcus multilocularis deoxyribonuclease ii 0.0073 0.044 0.044
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Onchocerca volvulus 0.0179 0.1334 0.5397
Trichomonas vaginalis DNAse2-prov protein, putative 0.0073 0.044 0.0525
Onchocerca volvulus 0.003 0.0072 0.0291
Trichomonas vaginalis AGC family protein kinase 0.0101 0.0669 0.0996
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0093 0.0602 0.0602
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0093 0.0602 0.0602
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0211 0.1602 0.2908
Toxoplasma gondii subtilisin SUB1 0.0047 0.0214 0.0142
Schistosoma mansoni tyrosine kinase 0.0064 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0018
Toxoplasma gondii subtilisin SUB5 0.0047 0.0214 0.0142
Schistosoma mansoni neuropeptide F-like receptor 0.0179 0.1334 0.1334
Brugia malayi Serotonin receptor 0.0179 0.1334 0.1608
Echinococcus multilocularis dnaJ subfamily B 0.1206 1 1
Entamoeba histolytica protein kinase, putative 0.0101 0.0669 0.4523
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0258 0.1995 0.3715
Plasmodium falciparum subtilisin-like protease 2 0.0047 0.0214 0.0266
Leishmania major beta tubulin 0.0089 0.0569 1
Echinococcus granulosus tyrosine kinase 0.0079 0.0484 0.0484
Schistosoma mansoni tyrosine kinase 0.0207 0.1564 0.1564
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0184 0.0181
Brugia malayi SWIB/MDM2 domain containing protein 0.0043 0.0184 0.0221
Giardia lamblia Beta tubulin 0.0089 0.0569 0.1077
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0025 0.0033 0.0039
Echinococcus granulosus neuropeptide s receptor 0.0675 0.5519 0.5519
Echinococcus multilocularis g protein coupled receptor 0.0179 0.1334 0.1334
Onchocerca volvulus 0.0179 0.1334 0.5397
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0124 0.0869 0.1047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Onchocerca volvulus 0.0062 0.0343 0.1389
Echinococcus granulosus tyrosine protein kinase csk 0.0036 0.0127 0.0127
Trypanosoma brucei beta tubulin 0.0089 0.0569 0.1537
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0079 0.0484 0.0484
Echinococcus multilocularis g protein coupled receptor 0.0179 0.1334 0.1334
Echinococcus granulosus neuropeptides capa receptor 0.0179 0.1334 0.1334
Brugia malayi proprotein convertase 2 0.0641 0.5231 0.6305
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0258 0.1995 0.3715
Brugia malayi AKH receptor 0.0179 0.1334 0.1608
Brugia malayi Protein kinase domain containing protein 0.0028 0.0061 0.0073
Entamoeba histolytica protein kinase, putative 0.0064 0.0364 0.203
Echinococcus multilocularis neuropeptide s receptor 0.0675 0.5519 0.5519
Plasmodium vivax tubulin beta chain, putative 0.0089 0.0569 0.3459
Onchocerca volvulus 0.0025 0.0033 0.0132
Schistosoma mansoni histamine h1 receptor 0.0179 0.1334 0.1334
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0318 0.0318
Echinococcus multilocularis fmrfamide receptor 0.0179 0.1334 0.1334
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0669 0.0669
Echinococcus multilocularis epidermal growth factor receptor 0.0139 0.0995 0.0995
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0025 0.0033 0.0039
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0179 0.1334 0.1334
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0179 0.1334 0.1334
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0047 0.0214 1
Brugia malayi hypothetical protein 0.0179 0.1334 0.1608
Echinococcus granulosus neuropeptide Y receptor 0.0179 0.1334 0.1334
Leishmania major beta tubulin 0.0089 0.0569 1
Brugia malayi Tyrosine-protein kinase abl-1 0.011 0.0753 0.0907
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Echinococcus granulosus tyrosine protein kinase HCK 0.0064 0.0364 0.0364
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0179 0.1334 0.1334
Toxoplasma gondii PAN domain-containing protein 0.0299 0.2342 1
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1602 0.2908
Onchocerca volvulus 0.0023 0.0018 0.0073
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Brugia malayi photoreceptor-specific nuclear receptor 0.0025 0.0033 0.0039
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0179 0.1334 0.1334
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0033 0.0103 0.0103
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0179 0.1334 0.1334
Trichomonas vaginalis hypothetical protein 0.0211 0.1602 0.2908
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0025 0.0033 0.0039
Schistosoma mansoni tubulin subunit beta 0.0089 0.0569 0.0569
Echinococcus multilocularis neuroendocrine convertase 2 0.0641 0.5231 0.5231
Loa Loa (eye worm) hypothetical protein 0.1005 0.8296 1
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.018 0.1339 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0265 0.0377
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.018 0.1339 0.2368
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0056 0.0289 0.0349
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0116 0.0116
Schistosoma mansoni neuropeptide receptor 0.0179 0.1334 0.1334
Loa Loa (eye worm) deoxyribonuclease II family protein 0.0073 0.044 0.053
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Echinococcus multilocularis FTZ F1 alpha 0.0025 0.0033 0.0033
Echinococcus granulosus allatostatin A receptor 0.0314 0.2472 0.2472
Echinococcus multilocularis serotonin receptor 0.0179 0.1334 0.1334
Echinococcus multilocularis somatostatin receptor 0.0179 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni biogenic amine receptor 0.0179 0.1334 0.1334
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0093 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Echinococcus multilocularis allatostatin A receptor 0.0314 0.2472 0.2472
Brugia malayi Calcitonin receptor-like protein seb-1 0.0167 0.1226 0.1478
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0056 0.0289 0.0289
Schistosoma mansoni hypothetical protein 0.1206 1 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0039
Schistosoma mansoni tyrosine kinase 0.0093 0.0602 0.0602
Echinococcus granulosus dro:myosuppressin receptor 0.0179 0.1334 0.1334
Echinococcus multilocularis SWI:SNF matrix associated 0.0043 0.0184 0.0184
Trichomonas vaginalis tubulin epsilon chain, putative 0.0089 0.0569 0.0791
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0025 0.0033 0.0039
Loa Loa (eye worm) TK protein kinase 0.0079 0.0484 0.0584
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.018 0.1339 0.1339
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0258 0.1995 0.3715
Schistosoma mansoni hypothetical protein 0.0103 0.0686 0.0686
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Trypanosoma brucei lanosterol synthase 0.0061 0.0335 0.0522
Loa Loa (eye worm) hypothetical protein 0.0179 0.1334 0.1608
Schistosoma mansoni neuropeptide f receptor 76f 0.0179 0.1334 0.1334
Schistosoma mansoni hypothetical protein 0.0023 0.0015 0.0015
Brugia malayi hypothetical protein 0.0179 0.1334 0.1608
Brugia malayi protein-tyrosine kinase 0.0079 0.0484 0.0584
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0479 0.3858 0.3858
Schistosoma mansoni site-1 peptidase (S08 family) 0.0047 0.0214 0.0214
Brugia malayi SRC-1 0.0093 0.0602 0.0725
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0025 0.0033 0.0033
Onchocerca volvulus 0.0179 0.1334 0.5397
Echinococcus granulosus tyrosine protein kinase Src42A 0.0093 0.0602 0.0602
Schistosoma mansoni amine GPCR 0.0179 0.1334 0.1334
Brugia malayi larval opioid receptor 0.0179 0.1334 0.1608
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0025 0.0033 0.0039
Echinococcus granulosus tyrosine protein kinase csk 0.0036 0.0127 0.0127
Schistosoma mansoni neuropeptide F-like receptor 0.0179 0.1334 0.1334
Leishmania major beta tubulin 0.0089 0.0569 1
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0056 0.0289 0.0217
Echinococcus granulosus tm gpcr rhodopsin 0.0179 0.1334 0.1334
Onchocerca volvulus 0.0179 0.1334 0.5397
Brugia malayi Melatonin receptor type 1A 0.0179 0.1334 0.1608
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0039
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0179 0.1334 0.1334
Brugia malayi Deoxyribonuclease II family protein 0.0073 0.044 0.053
Brugia malayi Protein kinase domain containing protein 0.0023 0.0018 0.0022
Brugia malayi G-protein coupled receptor 0.0179 0.1334 0.1608
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0025 0.0033 0.0033
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.1005 0.8296 0.8296
Schistosoma mansoni cpg binding protein 0.0028 0.0055 0.0055
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0062 0.0343 0.0343
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0179 0.1334 0.1334
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.1334 0.1334
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0025 0.0033 0.0033
Schistosoma mansoni furin-1 (S08 family) 0.043 0.345 0.345
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0214 0.0063
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0047 0.0214 0.0063
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0064 0.0361 0.0361

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.42 uM Antiproliferative activity against human SKBR3 cells expressing HER2 after 72 hrs by MTS/PMS assay ChEMBL. 21553822
IC50 (functional) = 0.58 uM Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 72 hrs by MTS/PMS assay ChEMBL. 21553822

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 21553822

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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