Detailed information for compound 989148

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 333.42 | Formula: C16H31NO6
  • H donors: 4 H acceptors: 5 LogP: 1.94 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCOC(=O)N1C[C@H](O)[C@H]([C@@H]([C@H]1CO)O)O
  • InChi: 1S/C16H31NO6/c1-2-3-4-5-6-7-8-9-23-16(22)17-10-13(19)15(21)14(20)12(17)11-18/h12-15,18-21H,2-11H2,1H3/t12-,13+,14-,15-/m1/s1
  • InChiKey: ZDKHIJYWALSAFU-LXTVHRRPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucosidase, beta (bile acid) 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus non lysosomal glucosylceramidase Get druggable targets OG5_130651 All targets in OG5_130651
Echinococcus granulosus bile acid beta glucosidase Get druggable targets OG5_130651 All targets in OG5_130651
Echinococcus multilocularis non lysosomal glucosylceramidase Get druggable targets OG5_130651 All targets in OG5_130651
Schistosoma mansoni bile acid beta-glucosidase-related Get druggable targets OG5_130651 All targets in OG5_130651
Echinococcus multilocularis bile acid beta glucosidase Get druggable targets OG5_130651 All targets in OG5_130651
Schistosoma japonicum Non-lysosomal glucosylceramidase, putative Get druggable targets OG5_130651 All targets in OG5_130651
Schistosoma mansoni bile acid beta-glucosidase-related Get druggable targets OG5_130651 All targets in OG5_130651
Schistosoma japonicum Non-lysosomal glucosylceramidase, putative Get druggable targets OG5_130651 All targets in OG5_130651
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130651 All targets in OG5_130651
Schistosoma japonicum Non-lysosomal glucosylceramidase, putative Get druggable targets OG5_130651 All targets in OG5_130651
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) AGC/AKT protein kinase 0.0308 0.2559 0.2768
Entamoeba histolytica protein kinase, putative 0.0308 0.2559 0.3014
Schistosoma mansoni ephrin receptor 0.0113 0.0572 0.0674
Onchocerca volvulus 0.0106 0.0492 0.095
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0164 0.1086 0.1278
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Echinococcus multilocularis serine:threonine protein kinase N2 0.0175 0.1203 0.1417
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0079 0.0217 0.0217
Trichomonas vaginalis CMGC family protein kinase 0.089 0.8491 1
Brugia malayi Variant SH3 domain containing protein 0.0092 0.0356 0.0385
Loa Loa (eye worm) hypothetical protein 0.019 0.1351 0.1461
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0193 0.1389 0.1635
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0161 0.1054 0.1038
Echinococcus multilocularis mitogen activated protein kinase 11 0.0166 0.1111 0.1309
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0416 0.3655 0.4305
Echinococcus multilocularis rho associated protein kinase 0.0335 0.2836 0.334
Schistosoma mansoni serine/threonine protein kinase 0.0221 0.1674 0.1971
Echinococcus multilocularis cyclin dependent kinase 1 0.089 0.8491 1
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2559 0.3003
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.089 0.8491 0.9185
Brugia malayi Hr1 repeat family protein 0.0307 0.255 0.2758
Brugia malayi Protein kinase domain containing protein 0.0458 0.4088 0.4422
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0095 0.0386 0.0454
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0266 0.2125 0.2503
Brugia malayi Doublecortin family protein 0.0158 0.1025 0.1109
Loa Loa (eye worm) hypothetical protein 0.0141 0.0857 0.0927
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0135 0.0795 0.0936
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0391 0.0446
Entamoeba histolytica protein kinase, putative 0.0077 0.0198 0.0233
Trichomonas vaginalis cyclins, putative 0.0076 0.0193 0.0213
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0266 0.2125 0.2503
Echinococcus granulosus tyrosine protein kinase Src64B 0.0266 0.2125 0.2125
Brugia malayi ephrin receptor 1 precursor 0.0079 0.022 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.1984 0.2336
Brugia malayi RhoGAP domain containing protein 0.0092 0.0356 0.0385
Trichomonas vaginalis cyclin A, putative 0.0076 0.0193 0.0213
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.025 0.1967 0.2316
Brugia malayi Tyrosine-protein kinase abl-1 0.0225 0.1707 0.1847
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0089 0.0322 0.0155
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0301 0.2488 0.2691
Entamoeba histolytica PH domain containing protein kinase, putative 0.0171 0.1157 0.1363
Trypanosoma brucei protein kinase, putative 0.0086 0.0292 0.0119
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0152 0.097 0.1142
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0171 0.1163 0.137
Plasmodium vivax calcium-dependent protein kinase, putative 0.0107 0.0506 0.0525
Trichomonas vaginalis CMGC family protein kinase 0.089 0.8491 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0107 0.0506 0.0525
Brugia malayi Casein kinase II, alpha chain 0.0106 0.0498 0.0539
Echinococcus granulosus bile acid beta glucosidase 0.0251 0.198 0.198
Giardia lamblia Kinase, CAMK CAMKL 0.0095 0.0387 0.0233
Giardia lamblia Aurora kinase 0.0152 0.097 0.0936
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0079 0.0217 0.0234
Schistosoma mansoni serine/threonine kinase 0.0225 0.1712 0.2017
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0217 0.0255
Giardia lamblia Kinase, NEK 0.0143 0.0873 0.0819
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0092 0.0356 0.0356
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0079 0.0217 0.0028
Loa Loa (eye worm) hypothetical protein 0.0083 0.0263 0.0284
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0092 0.0356 0.0419
Loa Loa (eye worm) hypothetical protein 0.0095 0.0387 0.0419
Loa Loa (eye worm) TK/ALK protein kinase 0.0289 0.2364 0.2557
Brugia malayi Protein kinase domain containing protein 0.0201 0.1461 0.1581
Echinococcus granulosus tyrosine protein kinase Src42A 0.0181 0.1263 0.1263
Plasmodium falciparum cGMP-dependent protein kinase 0.0141 0.0857 0.0774
Entamoeba histolytica protein kinase, putative 0.0077 0.0198 0.0233
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0107 0.0506 0.0596
Plasmodium vivax glycogen synthase kinase 3, putative 0.0135 0.0795 0.0868
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0092 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.017 0.1146 0.124
Schistosoma mansoni tyrosine kinase 0.0323 0.271 0.3192
Schistosoma mansoni tyrosine kinase 0.0379 0.3284 0.3868
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0188 0.1329 0.1565
Echinococcus multilocularis dual specificity 0.0092 0.0351 0.0414
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0231 0.1767 0.1911
Entamoeba histolytica protein kinase domain containing protein 0.0086 0.0292 0.0344
Onchocerca volvulus 0.0076 0.0193 0.0373
Toxoplasma gondii CMGC kinase, CK2 family 0.0106 0.0498 0.0341
Loa Loa (eye worm) hypothetical protein 0.0101 0.0444 0.0481
Echinococcus granulosus non lysosomal glucosylceramidase 0.0251 0.198 0.198
Echinococcus granulosus cyclin dependent kinase 1 0.089 0.8491 0.8491
Entamoeba histolytica protein kinase, putative 0.0152 0.097 0.1142
Loa Loa (eye worm) hypothetical protein 0.0146 0.0907 0.0981
Onchocerca volvulus 0.0141 0.0857 0.1655
Onchocerca volvulus 0.0135 0.0795 0.1535
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0506 0.0596
Schistosoma mansoni serine/threonine protein kinase 0.0307 0.255 0.3003
Trichomonas vaginalis CK1 family protein kinase 0.0115 0.0587 0.0677
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Trypanosoma cruzi casein kinase, putative 0.0115 0.0587 0.0663
Echinococcus granulosus nervana 2 0.0126 0.07 0.07
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0026 0.0031
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0095 0.0387 0.0233
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0106 0.0498 0.0516
Echinococcus granulosus NCK adaptor protein 0.0096 0.0392 0.0392
Schistosoma mansoni serine/threonine protein kinase 0.089 0.8491 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.007 0.0132 0.0156
Brugia malayi protein kinase C3,putative 0.0157 0.1018 0.1101
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0211 0.1572 0.17
Trichomonas vaginalis CK1 family protein kinase 0.0115 0.0587 0.0677
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0092 0.0352 0.0352
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0351 0.0399
Trypanosoma cruzi polo-like protein kinase, putative 0.0087 0.0299 0.0323
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0135 0.0795 0.0909
Entamoeba histolytica protein kinase, putative 0.0129 0.0728 0.0858
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0305 0.0359
Echinococcus granulosus serine:threonine protein kinase N2 0.0307 0.255 0.255
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0135 0.0795 0.0795
Schistosoma mansoni serine/threonine protein kinase 0.0335 0.2836 0.334
Echinococcus granulosus N chimaerin 0.0092 0.0356 0.0356
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0261 0.2077 0.2247
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0135 0.0795 0.0699
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0171 0.1163 0.1163
Brugia malayi hypothetical protein 0.0125 0.0695 0.0752
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0189 0.0222
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0092 0.0351 0.0163
Echinococcus multilocularis calcium dependent protein kinase 0.0069 0.012 0.0142
Schistosoma mansoni vav2 0.0099 0.0427 0.0503
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0175 0.1203 0.1203
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0474 0.4251 0.5006
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0299 0.0337
Loa Loa (eye worm) hypothetical protein 0.0125 0.0695 0.0752
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0096 0.0392 0.0424
Brugia malayi Fes/CIP4 homology domain containing protein 0.0116 0.0595 0.0644
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0266 0.2125 0.2503
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0121 0.0649 0.0702
Echinococcus multilocularis serine:threonine protein kinase 38 0.0175 0.1203 0.1417
Echinococcus multilocularis expressed conserved protein 0.0141 0.0857 0.1009
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0092 0.0352 0.0414
Echinococcus multilocularis protein kinase c epsilon type 0.0211 0.1572 0.1851
Loa Loa (eye worm) AGC/PKG protein kinase 0.0141 0.0857 0.0927
Echinococcus granulosus expressed protein 0.0089 0.0322 0.0322
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0076 0.0194 0.0229
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Plasmodium falciparum serine/threonine protein kinase KIN 0.0095 0.0387 0.0206
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0163 0.1081 0.1169
Plasmodium falciparum calcium-dependent protein kinase 5 0.0107 0.0506 0.035
Echinococcus multilocularis activin receptor type 0.0086 0.0292 0.0344
Onchocerca volvulus Serine\/threonine kinase homolog 0.0087 0.0299 0.0577
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0107 0.0506 0.0525
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.1054 0.1242
Loa Loa (eye worm) hypothetical protein 0.0065 0.008 0.0087
Brugia malayi Protein kinase domain containing protein 0.057 0.5228 0.5655
Echinococcus granulosus growth factor receptor bound protein 2 0.0098 0.0412 0.0412
Echinococcus granulosus cyclin B 0.0076 0.0193 0.0193
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.1389 0.1635
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0161 0.1054 0.1215
Schistosoma mansoni cell adhesion molecule 0.012 0.0635 0.0747
Echinococcus granulosus serine:threonine protein kinase 0.012 0.0644 0.0644
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0266 0.2125 0.2125
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.089 0.8491 1
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0391 0.0446
Loa Loa (eye worm) hypothetical protein 0.0085 0.0285 0.0308
Plasmodium falciparum NIMA related kinase 1 0.0143 0.0873 0.0793
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0508 0.4595 0.5411
Echinococcus granulosus Glutaredoxin protein 5 0.0126 0.07 0.07
Trichomonas vaginalis AGC family protein kinase 0.0152 0.097 0.1128
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.1563 0.1841
Onchocerca volvulus 0.0096 0.0391 0.0755
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0079 0.0217 0.0255
Echinococcus multilocularis mitogen activated protein kinase 11 0.0166 0.1111 0.1309
Trypanosoma brucei casein kinase I, isoform 2 0.0115 0.0587 0.0475
Entamoeba histolytica cyclin, putative 0.0076 0.0193 0.0228
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0152 0.0963 0.0963
Echinococcus granulosus cyclin dependent kinase 0.089 0.8491 0.8491
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0129 0.0728 0.083
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0087 0.0305 0.0359
Giardia lamblia Kinase, CK1 Casein kinase 0.0115 0.0587 0.0475
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0728 0.0858
Schistosoma mansoni tyrosine kinase 0.0564 0.5165 0.6083
Echinococcus multilocularis serine:threonine protein kinase N2 0.0132 0.0762 0.0898
Onchocerca volvulus 0.0125 0.069 0.1332
Trypanosoma cruzi casein kinase, putative 0.0115 0.0587 0.0663
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0121 0.0654 0.0654
Leishmania major protein kinase A catalytic subunit 0.0079 0.0217 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0152 0.097 0.1142
Echinococcus granulosus tyrosine protein kinase Fyn 0.0266 0.2125 0.2125
Echinococcus multilocularis casein kinase i 0.0115 0.0587 0.0692
Onchocerca volvulus 0.0077 0.0201 0.0389
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.009 0.0328 0.0357
Schistosoma mansoni growth factor receptor-bound protein 0.0098 0.0412 0.0486
Onchocerca volvulus 0.0106 0.0492 0.095
Brugia malayi Protein kinase domain containing protein 0.0106 0.0492 0.0532
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0262 0.2089 0.246
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0107 0.0506 0.0547
Brugia malayi Protein kinase domain 0.0092 0.0352 0.0381
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0156 0.1004 0.1086
Echinococcus multilocularis casein kinase I gamma 0.0221 0.1674 0.1971
Plasmodium falciparum serine/threonine protein kinase 0.0089 0.0322 0.0127
Echinococcus multilocularis Immunoglobulin 0.0085 0.0282 0.0332
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0086 0.0292 0.0315
Loa Loa (eye worm) TK protein kinase 0.0292 0.2398 0.2594
Echinococcus granulosus serine:threonine kinase SAD 1 0.0095 0.0387 0.0387
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0135 0.0795 0.0936
Brugia malayi intracellular kinase 0.0135 0.0795 0.086
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0266 0.2125 0.2503
Brugia malayi Protein kinase domain containing protein 0.0209 0.1544 0.167
Entamoeba histolytica protein kinase, putative 0.0089 0.0322 0.0379
Loa Loa (eye worm) hypothetical protein 0.0104 0.0472 0.051
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0266 0.2125 0.2125
Toxoplasma gondii aurora kinase 0.0152 0.097 0.091
Brugia malayi Fibronectin type III domain containing protein 0.0101 0.0444 0.0481
Brugia malayi Temporarily assigned gene name protein 59 0.0131 0.0755 0.0817
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0492 0.0532
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0126 0.07 0.0824
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0262 0.0309
Brugia malayi Protein kinase domain containing protein 0.0292 0.2398 0.2594
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0266 0.2125 0.2503
Entamoeba histolytica protein kinase, putative 0.0129 0.0728 0.0858
Echinococcus granulosus roundabout 2 0.0142 0.086 0.086
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0087 0.0299 0.0299
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0211 0.1563 0.1691
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0092 0.0356 0.0419
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0166 0.1111 0.1202
Echinococcus multilocularis nervana 2 0.0126 0.07 0.0824
Echinococcus multilocularis hypothetical protein 0.0104 0.0474 0.0558
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0363 0.3121 0.3676
Echinococcus multilocularis c src tyrosine kinase 0.0144 0.0883 0.104
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0217 0.0255
Echinococcus multilocularis cyclin dependent kinase 5 0.089 0.8491 1
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0158 0.1025 0.1109
Onchocerca volvulus 0.0298 0.2451 0.4732
Echinococcus granulosus protein kinase c epsilon type 0.0211 0.1572 0.1572
Brugia malayi Immunoglobulin I-set domain containing protein 0.0646 0.601 0.6501
Echinococcus multilocularis serine:threonine protein kinase 0.012 0.0644 0.0758
Trypanosoma brucei aurora B kinase 0.0152 0.097 0.0936
Mycobacterium ulcerans haloalkane dehalogenase 0.0901 0.8611 1
Brugia malayi Protein kinase domain containing protein 0.0106 0.0492 0.0532
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0095 0.0387 0.0233
Loa Loa (eye worm) hypothetical protein 0.0075 0.0183 0.0197
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0107 0.0506 0.0506
Echinococcus granulosus hypothetical protein 0.0123 0.0669 0.0669
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0026 0.0031
Echinococcus granulosus defective proboscis extension response 0.0085 0.0282 0.0282
Echinococcus granulosus serine:threonine protein kinase 0.012 0.0644 0.0644
Echinococcus granulosus tyrosine kinase 0.0106 0.0492 0.0492
Loa Loa (eye worm) hypothetical protein 0.0057 0.0001 0.0002
Echinococcus multilocularis twitchin 0.006 0.0026 0.0031
Brugia malayi Immunoglobulin I-set domain containing protein 0.0101 0.0444 0.0481
Schistosoma mansoni protein kinase 0.0075 0.0175 0.0206
Entamoeba histolytica protein kinase, putative 0.0135 0.0795 0.0936
Giardia lamblia Kinase, CDC7 0.0096 0.0391 0.0238
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0615 0.5692 0.6157
Trypanosoma cruzi CYC2-like cyclin, putative 0.0076 0.0193 0.0198
Loa Loa (eye worm) casein kinase 0.0184 0.1288 0.1393
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0387 0.0456
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0152 0.097 0.1142
Trichomonas vaginalis CMGC family protein kinase 0.089 0.8491 1
Schistosoma mansoni vesicular amine transporter 0.0085 0.0282 0.0332
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.009 0.0328 0.0162
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2559 0.3003
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0107 0.0506 0.035
Echinococcus multilocularis dual specificity 0.0129 0.0728 0.0858
Entamoeba histolytica PH domain containing protein kinase, putative 0.0086 0.0288 0.0339
Brugia malayi putative serine/threonine kinase SADA gamma 0.0095 0.0387 0.0419
Loa Loa (eye worm) CAMK protein kinase 0.0076 0.0189 0.0204
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0201 0.1461 0.1581
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0508 0.4595 0.4595
Entamoeba histolytica protein kinase, putative 0.0087 0.0305 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.097 0.1142
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0227 0.1734 0.1734
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0175 0.1203 0.1417
Echinococcus granulosus casein kinase I delta 0.0115 0.0587 0.0587
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0123 0.0675 0.073
Plasmodium falciparum protein kinase 5 0.089 0.8491 1
Brugia malayi Furin-like cysteine rich region family protein 0.0624 0.5777 0.6249
Schistosoma mansoni tyrosine kinase 0.0266 0.2125 0.2503
Schistosoma mansoni tyrosine kinase 0.025 0.1967 0.2316
Brugia malayi Protein kinase domain containing protein 0.0106 0.0492 0.0532
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0492 0.0532
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0094 0.0379 0.041
Entamoeba histolytica protein kinase, putative 0.0175 0.1203 0.1417
Giardia lamblia Kinase, CMGC CLK 0.0161 0.1054 0.1038
Echinococcus granulosus protein tyrosine kinase 0.0564 0.5165 0.5165
Echinococcus multilocularis CDC7 cell division cycle 7 0.0096 0.0391 0.046
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0387 0.0456
Echinococcus granulosus casein kinase i 0.0115 0.0587 0.0587
Onchocerca volvulus 0.0065 0.008 0.0155
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0107 0.0506 0.0596
Loa Loa (eye worm) hypothetical protein 0.019 0.1351 0.1461
Plasmodium falciparum calcium-dependent protein kinase 4 0.0107 0.0506 0.035
Trypanosoma cruzi casein kinase, putative 0.0115 0.0587 0.0663
Schistosoma mansoni protein kinase 0.0188 0.1329 0.1565
Schistosoma mansoni growth factor receptor-bound protein 0.0096 0.0392 0.0461
Echinococcus multilocularis casein kinase I delta 0.0115 0.0587 0.0692
Trypanosoma cruzi casein kinase, putative 0.0115 0.0587 0.0663
Entamoeba histolytica casein kinase, putative 0.0115 0.0587 0.0692
Echinococcus multilocularis raf serine:threonine protein kinase 0.0083 0.0262 0.0309
Brugia malayi protein-tyrosine kinase 0.0227 0.1734 0.1875
Onchocerca volvulus Tyrosine kinase homolog 0.0565 0.5179 1
Brugia malayi Variant SH3 domain containing protein 0.0096 0.0392 0.0424
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0161 0.1054 0.1013
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0492 0.0532
Brugia malayi Stress-activated protein kinase jnk-1 0.0273 0.2204 0.2384
Brugia malayi Protein kinase domain containing protein 0.0161 0.1054 0.1141
Plasmodium falciparum casein kinase 1 0.0115 0.0587 0.0448
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0339 0.2876 0.311
Entamoeba histolytica cell division protein kinase 2, putative 0.089 0.8491 1
Echinococcus multilocularis bile acid beta glucosidase 0.0251 0.198 0.2331
Echinococcus multilocularis roundabout 2 0.0142 0.086 0.1013
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0299 0.0337
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Echinococcus multilocularis mitogen activated protein kinase 3 0.009 0.0328 0.0387
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.089 0.8491 0.9185
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0107 0.0506 0.0547
Echinococcus multilocularis expressed protein 0.0089 0.0322 0.0379
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0092 0.0352 0.0414
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0089 0.0322 0.0349
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0252 0.1984 0.2336
Loa Loa (eye worm) AGC/PKA protein kinase 0.0079 0.0217 0.0234
Schistosoma mansoni bile acid beta-glucosidase-related 0.0251 0.198 0.2331
Entamoeba histolytica protein kinase domain containing protein 0.0106 0.0498 0.0587
Trichomonas vaginalis AGC family protein kinase 0.0196 0.1415 0.1654
Echinococcus granulosus tyrosine protein kinase Fyn 0.0266 0.2125 0.2125
Giardia lamblia Kinase, CMGC GSK 0.0135 0.0795 0.0725
Giardia lamblia Kinase, AGC PKA 0.0164 0.1086 0.1075
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0115 0.0587 0.0663
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0196 0.1415 0.1531
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0087 0.03 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0107 0.0506 0.0377
Leishmania major protein kinase, putative 0.0107 0.0506 0.0377
Loa Loa (eye worm) hypothetical protein 0.0107 0.0506 0.0547
Brugia malayi SRC-1 0.0266 0.2125 0.2299
Onchocerca volvulus 0.0096 0.0391 0.0755
Toxoplasma gondii histone kinase SNF1, putative 0.0095 0.0387 0.0206
Echinococcus granulosus tyrosine protein kinase HCK 0.017 0.1149 0.1149
Trichomonas vaginalis STE family protein kinase 0.0092 0.0352 0.04
Giardia lamblia Kinase, STE STE20 0.0092 0.0352 0.0191
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.1702 0.2005
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0087 0.0299 0.0127
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2559 0.3003
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0328 0.0372
Echinococcus granulosus tyrosine protein kinase shark 0.0323 0.271 0.271
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0079 0.0217 0.0225
Schistosoma mansoni tyrosine kinase 0.0144 0.0883 0.104
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0506 0.0581
Brugia malayi Protein kinase domain containing protein 0.0615 0.5692 0.6157
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.1702 0.2005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0075 0.0175 0.0206
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0299 0.0337
Plasmodium falciparum protein kinase, putative 0.0086 0.0292 0.0092
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0164 0.1086 0.1252
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0095 0.0387 0.0427
Brugia malayi Protein kinase domain containing protein 0.0175 0.1203 0.1301
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0498 0.0572
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0363 0.3121 0.3376
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0224 0.1702 0.2005
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0299 0.0337
Echinococcus granulosus serine/threonine protein kinase 0.0171 0.1157 0.1157
Loa Loa (eye worm) AGC/PKA protein kinase 0.0079 0.0217 0.0234
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0066 0.0085 0.0091
Trypanosoma cruzi casein kinase II, putative 0.0106 0.0498 0.0558
Brugia malayi p70 ribosomal S6 kinase beta 0.0301 0.2488 0.2691
Loa Loa (eye worm) AGC/PKN protein kinase 0.0307 0.255 0.2758
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0857 0.1009
Loa Loa (eye worm) TK/ROR protein kinase 0.007 0.0132 0.0143
Onchocerca volvulus 0.0106 0.0492 0.095
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0086 0.0292 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.1054 0.1242
Brugia malayi serine/threonine protein kinase 6 0.0152 0.097 0.1049
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0224 0.1702 0.1702
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0087 0.03 0.0101
Trichomonas vaginalis STE family protein kinase 0.0092 0.0352 0.04
Onchocerca volvulus Serine\/threonine kinase homolog 0.0171 0.1163 0.2246
Plasmodium falciparum calcium-dependent protein kinase 1 0.0107 0.0506 0.035
Entamoeba histolytica serine/threonine protein kinase, putative 0.0087 0.0299 0.0352
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1767 0.2081
Loa Loa (eye worm) hypothetical protein 0.0091 0.0343 0.0371
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0193 0.1389 0.1502
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0273 0.2204 0.2384
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.1544 0.1819
Echinococcus multilocularis mitogen activated protein kinase 14 0.0166 0.1111 0.1309
Entamoeba histolytica cell division protein kinase 2, putative 0.089 0.8491 1
Echinococcus multilocularis Glutaredoxin protein 5 0.0126 0.07 0.0824
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0224 0.1702 0.1702
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0164 0.1086 0.1086
Brugia malayi serine/threonine-protein kinase 6 0.0152 0.097 0.1049
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0107 0.0506 0.035
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0092 0.0351 0.038
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0175 0.1203 0.1417
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0087 0.0299 0.0352
Schistosoma mansoni hypothetical protein 0.0104 0.0474 0.0558
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0166 0.1111 0.1106
Brugia malayi Variant SH3 domain containing protein 0.0096 0.0392 0.0424
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0795 0.0922
Echinococcus multilocularis death associated protein kinase 1 0.0868 0.8272 0.9743
Schistosoma mansoni hypothetical protein 0.0104 0.0474 0.0558
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Trypanosoma cruzi cdc2-related kinase 1 0.089 0.8491 1
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Echinococcus granulosus tyrosine protein kinase Lyn 0.0303 0.2511 0.2511
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0143 0.0873 0.0793
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0339 0.2876 0.311
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0129 0.0728 0.0645
Trypanosoma brucei protein kinase, putative 0.0135 0.0795 0.0725
Schistosoma mansoni serine/threonine kinase 0.0175 0.1203 0.1417
Echinococcus multilocularis neuroglian 0.0107 0.0507 0.0597
Echinococcus multilocularis casein kinase I delta 0.0115 0.0587 0.0692
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0328 0.0372
Echinococcus multilocularis ephrin type A receptor 4 A 0.0113 0.0572 0.0674
Echinococcus multilocularis Immunoglobulin 0.0085 0.0282 0.0332
Brugia malayi phosphoinositide-dependent protein kinase I 0.0087 0.0305 0.033
Echinococcus granulosus tyrosine protein kinase Srms 0.0521 0.4728 0.4728
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Echinococcus multilocularis tyrosine protein kinase Srms 0.0227 0.1734 0.2042
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0076 0.0194 0.0194
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0159 0.1034 0.1218
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0135 0.0795 0.086
Trypanosoma cruzi Protein kinase B 0.0171 0.1157 0.1336
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0299 0.0337
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.006 0.0026 0.0028
Schistosoma mansoni protein kinase 0.0092 0.0352 0.0414
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0092 0.0356 0.0419
Echinococcus granulosus casein kinase I gamma 0.0221 0.1674 0.1674
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0087 0.0299 0.0323
Echinococcus granulosus titin 0.0076 0.0189 0.0189
Echinococcus granulosus calcium dependent protein kinase 0.0069 0.012 0.012
Giardia lamblia Kinase, CMGC SRPK 0.0089 0.0322 0.0155
Echinococcus granulosus casein kinase I alpha 0.0115 0.0587 0.0587
Schistosoma mansoni nck2/grb4 0.0096 0.0392 0.0461
Schistosoma mansoni tyrosine kinase 0.0259 0.2062 0.2428
Echinococcus granulosus protein kinase c iota type 0.0295 0.242 0.242
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0129 0.0728 0.0788
Brugia malayi serine/threonine-protein kinase PAK 7 0.0241 0.187 0.2022
Schistosoma mansoni cyclin B 0.0076 0.0193 0.0228
Echinococcus multilocularis aurora kinase A 0.0152 0.097 0.1142
Echinococcus granulosus dual specificity protein kinase clk2 0.0161 0.1054 0.1054
Echinococcus granulosus neuroglian 0.0107 0.0507 0.0507
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0086 0.0292 0.0315
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0086 0.0292 0.0292
Entamoeba histolytica protein kinase domain containing protein 0.0211 0.1563 0.1841
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0859 0.1012
Entamoeba histolytica protein kinase, putative 0.0076 0.0194 0.0229
Echinococcus multilocularis tyrosine protein kinase HCK 0.017 0.1149 0.1353
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0363 0.3121 0.3376
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0498 0.0572
Schistosoma mansoni atypical protein kinase C 0.0301 0.2483 0.2925
Brugia malayi MAP kinase sur-1 0.009 0.0328 0.0355
Echinococcus multilocularis casein kinase I alpha 0.0115 0.0587 0.0692
Trichomonas vaginalis STE family protein kinase 0.0092 0.0352 0.04
Trypanosoma cruzi aurora B kinase, putative 0.0152 0.097 0.1115
Trypanosoma cruzi cyclin, putative 0.0076 0.0193 0.0198
Echinococcus multilocularis protein tyrosine kinase 0.0564 0.5165 0.6083
Trichomonas vaginalis cyclin B, putative 0.0076 0.0193 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0859 0.1012
Giardia lamblia Kinase, AGC PKA 0.0079 0.0217 0.0028
Loa Loa (eye worm) hypothetical protein 0.0076 0.0193 0.0209
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0328 0.0372
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.013 0.0746 0.0666
Echinococcus multilocularis 0.0123 0.0669 0.0788
Loa Loa (eye worm) thyroid receptor interactor 0.0116 0.0595 0.0644
Loa Loa (eye worm) hypothetical protein 0.0057 0.0001 0.0002
Schistosoma mansoni protein kinase 0.0086 0.0292 0.0344
Brugia malayi Protein kinase domain containing protein 0.0096 0.0391 0.0423
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0079 0.0217 0.0225
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0143 0.0873 0.1014
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Brugia malayi serine/threonine-protein kinase plk-2 0.0087 0.0299 0.0323
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0194 0.0229
Onchocerca volvulus 0.0106 0.0492 0.095
Loa Loa (eye worm) TK/EGFR protein kinase 0.0624 0.5777 0.6249
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0305 0.0344
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0193 0.1389 0.1389
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0196 0.1415 0.1654
Echinococcus multilocularis tyrosine protein kinase Abl 0.0225 0.1707 0.2011
Schistosoma mansoni protein kinase 0.0086 0.0292 0.0344
Loa Loa (eye worm) hypothetical protein 0.0083 0.0263 0.0284
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0211 0.1563 0.1691
Echinococcus multilocularis mitogen activated protein kinase 0.009 0.0328 0.0387
Echinococcus granulosus epidermal growth factor receptor 0.0624 0.5777 0.5777
Brugia malayi Protein kinase domain containing protein 0.0225 0.1712 0.1852
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0161 0.1054 0.1141
Schistosoma mansoni tyrosine kinase 0.0363 0.3123 0.3678
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0066 0.0085 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Schistosoma mansoni protein kinase 0.0446 0.3966 0.4672
Echinococcus multilocularis protein kinase c iota type 0.0295 0.242 0.285
Entamoeba histolytica protein kinase, putative 0.0076 0.0194 0.0229
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0092 0.0352 0.0414
Echinococcus granulosus dual specificity 0.0092 0.0351 0.0351
Schistosoma mansoni serine/threonine-protein kinase 0.0171 0.1157 0.1363
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.2077 0.2446
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0143 0.0873 0.096
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0351 0.0399
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0171 0.1163 0.1258
Echinococcus multilocularis protein kinase shaggy 0.0135 0.0795 0.0936
Loa Loa (eye worm) hypothetical protein 0.0123 0.0669 0.0723
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0273 0.2204 0.2596
Echinococcus granulosus c-Jun N-terminal kinases 0.0273 0.2204 0.2204
Echinococcus granulosus mitogen activated protein kinase 11 0.0166 0.1111 0.1111
Brugia malayi Protein kinase domain containing protein 0.0363 0.3121 0.3376
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0492 0.0532
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.089 0.8491 1
Leishmania major casein kinase, putative 0.0115 0.0587 0.0475
Plasmodium falciparum protein serine/threonine kinase-1 0.0161 0.1054 0.1013
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0305 0.0344
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0322 0.0379
Schistosoma mansoni tyrosine kinase 0.0412 0.3614 0.4257
Brugia malayi Protein kinase domain containing protein 0.0194 0.1392 0.1506
Schistosoma mansoni serine/threonine protein kinase 0.049 0.4414 0.5198
Schistosoma mansoni tyrosine kinase 0.0412 0.3614 0.4257
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0079 0.0217 0.0255
Trypanosoma cruzi cyclin, putative 0.0076 0.0193 0.0198
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0305 0.0344
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2559 0.3003
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0096 0.0392 0.0424
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0107 0.0506 0.0506
Leishmania major protein kinase, putative 0.0086 0.0292 0.0119
Loa Loa (eye worm) TK protein kinase 0.0227 0.1734 0.1875
Echinococcus granulosus c src tyrosine kinase 0.0144 0.0883 0.0883
Schistosoma mansoni protein kinase 0.0115 0.0587 0.0692
Echinococcus granulosus mitogen activated protein kinase 14 0.0166 0.1111 0.1111
Loa Loa (eye worm) hypothetical protein 0.0129 0.0731 0.079
Mycobacterium tuberculosis Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase) 0.0901 0.8611 0.5
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0266 0.2125 0.2503
Echinococcus granulosus dual specificity 0.0129 0.0728 0.0728
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0351 0.0399
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0266 0.2125 0.2503
Entamoeba histolytica hypothetical protein 0.0129 0.0728 0.0858
Trichomonas vaginalis cyclins, putative 0.0076 0.0193 0.0213
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0363 0.3121 0.3376
Plasmodium falciparum casein kinase 2, alpha subunit 0.0106 0.0498 0.0341
Trichomonas vaginalis AGC family protein kinase 0.0152 0.097 0.1128
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.007 0.0132 0.0132
Entamoeba histolytica protein kinase, putative 0.0152 0.097 0.1142
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0262 0.2089 0.246
Echinococcus multilocularis 0.0177 0.1219 0.1436
Loa Loa (eye worm) hypothetical protein 0.0118 0.0619 0.0669
Echinococcus granulosus titin 0.0076 0.0189 0.0189
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0615 0.5692 0.6157
Trypanosoma brucei protein kinase, putative 0.009 0.0328 0.0162
Echinococcus multilocularis insulin receptor 0.0458 0.4088 0.4815
Trypanosoma brucei cdc2-related kinase 3 0.089 0.8491 1
Echinococcus granulosus dual specificity 0.0092 0.0351 0.0351
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0351 0.0399
Schistosoma mansoni bile acid beta-glucosidase-related 0.0251 0.198 0.2331
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.1984 0.2336
Brugia malayi cell division control protein 2 homolog 0.089 0.8491 0.9185
Giardia lamblia Kinase, CAMK CAMKL 0.0095 0.0387 0.0233
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0089 0.0322 0.0127
Loa Loa (eye worm) hypothetical protein 0.0079 0.0217 0.0234
Brugia malayi Sex muscle abnormal protein 5 0.0096 0.0392 0.0424
Trypanosoma cruzi cdc2-related kinase 3 0.089 0.8491 1
Plasmodium falciparum glycogen synthase kinase 3 0.0135 0.0795 0.0699
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.009 0.0328 0.0357
Schistosoma mansoni tyrosine kinase 0.0266 0.2125 0.2503
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Schistosoma mansoni protein kinase 0.0446 0.3966 0.4672
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0129 0.0728 0.083
Echinococcus granulosus nervana 2 0.0126 0.07 0.07
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.089 0.8491 0.8491
Schistosoma mansoni tyrosine kinase 0.0266 0.2125 0.2503
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0492 0.0532
Echinococcus granulosus tyrosine protein kinase Fyn 0.0266 0.2125 0.2125
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0141 0.0857 0.1009
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0095 0.0387 0.0427
Echinococcus multilocularis calcium activated potassium channel 0.0142 0.0859 0.1012
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.006 0.0026 0.0015
Giardia lamblia Kinase, CMGC DYRK 0.0092 0.0351 0.019
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0498 0.0572
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0079 0.0217 0.0217
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0092 0.0352 0.0352
Schistosoma mansoni tyrosine kinase 0.0363 0.3123 0.3678
Echinococcus granulosus serine threonine protein kinase nrc 0.0164 0.1086 0.1086
Brugia malayi Protein kinase domain containing protein 0.0087 0.0305 0.033
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0076 0.0194 0.0194
Loa Loa (eye worm) protein kinase domain-containing protein 0.0221 0.1674 0.181
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0086 0.0292 0.0344
Echinococcus granulosus mitogen activated protein kinase 0.009 0.0328 0.0328
Giardia lamblia Kinase, CMGC CK2 0.0106 0.0498 0.0368
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0498 0.0572
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0175 0.1203 0.1203
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.089 0.8491 0.9185
Echinococcus granulosus serine:threonine protein kinase N2 0.0132 0.0762 0.0762
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.009 0.0328 0.0135
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0141 0.0857 0.0774
Brugia malayi Protein kinase domain containing protein 0.0308 0.2559 0.2768
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0351 0.0399
Entamoeba histolytica casein kinase, putative 0.0106 0.0498 0.0587
Echinococcus granulosus rho-associated protein kinase 1 0.0335 0.2836 0.2836
Loa Loa (eye worm) hypothetical protein 0.0064 0.0071 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0351 0.0414
Trichomonas vaginalis cyclin B, putative 0.0076 0.0193 0.0213
Brugia malayi protein kinase C II. 0.0211 0.1572 0.17
Entamoeba histolytica protein kinase, putative 0.017 0.1149 0.1353
Entamoeba histolytica protein kinase, putative 0.0108 0.0519 0.0611
Loa Loa (eye worm) AUR protein kinase 0.0152 0.097 0.1049
Echinococcus granulosus protein kinase C gamma type 0.0217 0.1628 0.1628
Echinococcus granulosus casein kinase I alpha 0.0115 0.0587 0.0587
Brugia malayi P38 map kinase family protein 2 0.0166 0.1111 0.1202
Echinococcus multilocularis fibroblast growth factor receptor 4 0.025 0.1967 0.2316
Brugia malayi Protein kinase domain containing protein 0.0963 0.9245 1
Loa Loa (eye worm) hypothetical protein 0.0317 0.2645 0.2861
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.1203 0.1417
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.1572 0.1851
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0095 0.0387 0.0384
Entamoeba histolytica protein kinase, putative 0.0301 0.2488 0.293
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0387 0.0456
Loa Loa (eye worm) hypothetical protein 0.0176 0.1212 0.1312
Entamoeba histolytica PH domain containing protein kinase, putative 0.0171 0.1157 0.1363
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0092 0.0351 0.019
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0261 0.2077 0.2446
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0135 0.0795 0.086
Echinococcus multilocularis cyclin dependent kinase 0.089 0.8491 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0266 0.2125 0.2503
Brugia malayi hypothetical protein 0.0057 0.0001 0.0002
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0095 0.0387 0.0456
Brugia malayi casein kinase I 0.0115 0.0587 0.0635
Onchocerca volvulus 0.0106 0.0492 0.095
Echinococcus granulosus tyrosine protein kinase ABL1 0.0317 0.2647 0.2647
Brugia malayi Tyrosine-protein kinase abl-1 0.013 0.0746 0.0807
Brugia malayi Protein kinase domain containing protein 0.0129 0.0728 0.0788
Giardia lamblia Kinase, CMGC CDK 0.089 0.8491 1
Echinococcus granulosus aurora kinase A 0.0152 0.097 0.097
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0209 0.1544 0.1544
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0262 0.2089 0.2089
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0227 0.1734 0.2042
Onchocerca volvulus 0.0083 0.0263 0.0508
Brugia malayi Protein kinase domain containing protein 0.0196 0.1415 0.1531
Entamoeba histolytica protein kinase , putative 0.0152 0.097 0.1142
Loa Loa (eye worm) TK/INSR protein kinase 0.0458 0.4088 0.4422
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0158 0.103 0.1199
Echinococcus multilocularis tyrosine kinase 0.0106 0.0492 0.0579
Echinococcus multilocularis serine:threonine protein kinase N2 0.0307 0.255 0.3003
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0066 0.0085 0.0084
Trichomonas vaginalis STE family protein kinase 0.007 0.0127 0.0134
Loa Loa (eye worm) hypothetical protein 0.0141 0.0857 0.0927
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0107 0.0506 0.035
Onchocerca volvulus 0.0335 0.2836 0.5477
Loa Loa (eye worm) TK/FER protein kinase 0.0238 0.1843 0.1993
Giardia lamblia Kinase, CMGC GSK 0.0135 0.0795 0.0725
Trichomonas vaginalis AGC family protein kinase 0.0203 0.1487 0.1738
Brugia malayi Immunoglobulin I-set domain containing protein 0.0076 0.0189 0.0204
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0317 0.2647 0.3117
Loa Loa (eye worm) hypothetical protein 0.0091 0.0343 0.0371
Echinococcus multilocularis epidermal growth factor receptor 0.0624 0.5777 0.6804
Loa Loa (eye worm) hypothetical protein 0.0076 0.0193 0.0209
Echinococcus granulosus ephrin type A receptor 4 A 0.0113 0.0572 0.0572
Echinococcus granulosus tyrosine kinase 0.0227 0.1734 0.1734
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0079 0.0217 0.0255
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0328 0.0387
Schistosoma mansoni tyrosine kinase 0.008 0.0233 0.0274
Echinococcus granulosus CDC7 cell division cycle 7 0.0096 0.0391 0.0391
Onchocerca volvulus 0.0106 0.0492 0.095
Giardia lamblia Kinase, CMGC CDK 0.089 0.8491 1
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0391 0.046
Trichomonas vaginalis cyclin B, putative 0.0076 0.0193 0.0213
Entamoeba histolytica protein kinase 2, putative 0.0164 0.1086 0.1278
Schistosoma mansoni protein kinase 0.0446 0.3966 0.4672
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0624 0.0735
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0261 0.2077 0.2077
Plasmodium vivax casein kinase 1, putative 0.0115 0.0587 0.0621
Brugia malayi Serine/threonine-protein kinase SULU 0.0231 0.1767 0.1911
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0107 0.0506 0.0506
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0152 0.097 0.097
Giardia lamblia Kinase, CMGC MAPK 0.009 0.0328 0.0162
Trichomonas vaginalis CK1 family protein kinase 0.0115 0.0587 0.0677
Echinococcus granulosus activin receptor type 0.0086 0.0292 0.0292
Brugia malayi Immunoglobulin I-set domain containing protein 0.0272 0.2192 0.2371
Echinococcus multilocularis titin 0.0076 0.0189 0.0222
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0164 0.1086 0.105
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0299 0.0337
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0106 0.0492 0.0579
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0412 0.3614 0.3614
Echinococcus granulosus tyrosine protein kinase Src42A 0.0266 0.2125 0.2125
Loa Loa (eye worm) TK protein kinase 0.0181 0.1258 0.136
Loa Loa (eye worm) hypothetical protein 0.0615 0.5692 0.6157
Brugia malayi Protein kinase domain containing protein 0.0289 0.2365 0.2558
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0238 0.1843 0.1843
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0106 0.0498 0.0539
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0026 0.0031
Brugia malayi Egg laying defective protein 4 0.0141 0.0857 0.0927
Trypanosoma brucei cdc2-related kinase 1 0.089 0.8491 1
Schistosoma mansoni protein kinase 0.0106 0.0498 0.0587
Echinococcus multilocularis dual specificity 0.0092 0.0351 0.0414
Plasmodium vivax unspecified product 0.0106 0.0498 0.0516
Brugia malayi Protein kinase domain containing protein 0.0194 0.1398 0.1513
Entamoeba histolytica hypothetical protein 0.0387 0.3364 0.3962
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0954 0.1124
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0079 0.0226 0.0244
Brugia malayi probable protein kinase 0.0075 0.0175 0.0189
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0193 0.1389 0.1502
Loa Loa (eye worm) hypothetical protein 0.0141 0.0857 0.0927
Brugia malayi hypothetical protein 0.0231 0.1767 0.1911
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0076 0.0189 0.0204
Trypanosoma cruzi polo-like protein kinase, putative 0.0087 0.0299 0.0323
Echinococcus granulosus casein kinase ii subunit alpha 0.0106 0.0498 0.0498
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0498 0.0572
Toxoplasma gondii AGC kinase 0.0301 0.2488 0.2745
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0363 0.3121 0.3121
Brugia malayi Protein kinase domain containing protein 0.089 0.8491 0.9185
Entamoeba histolytica protein kinase domain containing protein 0.0135 0.0795 0.0936
Brugia malayi C1-like domain containing protein 0.0156 0.1004 0.1086
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.0728 0.0858
Echinococcus multilocularis nervana 2 0.0126 0.07 0.0824
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0085 0.0282 0.0332
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0166 0.1111 0.1106
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0474 0.4251 0.4251
Brugia malayi protein unc-22 0.0076 0.0189 0.0204
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0188 0.1329 0.1329
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0446 0.3966 0.3966
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Loa Loa (eye worm) hypothetical protein 0.0085 0.0282 0.0305
Brugia malayi serine/threonine kinase 12 0.0152 0.097 0.1049
Toxoplasma gondii casein kinase I 0.0115 0.0587 0.0448
Brugia malayi hypothetical protein 0.0101 0.0444 0.0481
Echinococcus granulosus fibroblast growth factor receptor 4 0.025 0.1967 0.1967
Echinococcus multilocularis epidermal growth factor receptor 0.0412 0.3614 0.4257
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.2204 0.2596
Loa Loa (eye worm) hypothetical protein 0.0125 0.069 0.0746
Echinococcus multilocularis tyrosine protein kinase Blk 0.0227 0.1734 0.2042
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0092 0.0351 0.019
Echinococcus granulosus twitchin 0.0145 0.0893 0.0893
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0126 0.07 0.07
Schistosoma mansoni tyrosine kinase 0.0363 0.3123 0.3678
Echinococcus granulosus NDR protein kinase 0.0175 0.1203 0.1203
Entamoeba histolytica PH domain containing protein kinase, putative 0.0086 0.0288 0.0339
Brugia malayi SH2 domain containing protein 0.0106 0.0492 0.0532
Echinococcus multilocularis cyclin B 0.0076 0.0193 0.0228
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0224 0.1702 0.2005
Brugia malayi Protein kinase domain containing protein 0.0106 0.0492 0.0532
Schistosoma mansoni serine/threonine-protein kinase 0.0171 0.1157 0.1363
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0406 0.3554 0.3844
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0231 0.1767 0.2081
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0077 0.0201 0.0207
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0351 0.0399
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0144 0.0883 0.104
Giardia lamblia Kinase, NEK 0.0143 0.0873 0.0819
Schistosoma mansoni protein kinase C mu 0.0156 0.1004 0.1183
Schistosoma mansoni tyrosine kinase 0.0624 0.5777 0.6804
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.009 0.0328 0.0162
Loa Loa (eye worm) hypothetical protein 0.047 0.4209 0.4553
Schistosoma mansoni protein kinase 0.0086 0.0292 0.0344
Schistosoma mansoni serine/threonine protein kinase 0.0363 0.3121 0.3676
Schistosoma mansoni protein kinase 0.0201 0.1461 0.1721
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0079 0.0217 0.0225
Schistosoma mansoni adapter molecule crk 0.0096 0.0392 0.0461
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0209 0.1544 0.1818
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0299 0.0352
Echinococcus granulosus epidermal growth factor receptor 0.0412 0.3614 0.3614
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0092 0.0351 0.0384
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.009 0.0328 0.0357
Echinococcus granulosus cGMP dependent protein kinase 1 0.0141 0.0857 0.0857
Plasmodium falciparum calcium-dependent protein kinase 3 0.0107 0.0506 0.035
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0209 0.1544 0.167
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0654 0.0756
Entamoeba histolytica protein kinase, putative 0.007 0.0127 0.0149
Loa Loa (eye worm) TK protein kinase 0.017 0.1149 0.1242
Loa Loa (eye worm) AUR protein kinase 0.0152 0.097 0.1049
Brugia malayi Protein kinase domain containing protein 0.0106 0.0492 0.0532
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2559 0.3003
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0107 0.0506 0.0596
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0166 0.1111 0.1282
Echinococcus multilocularis dual specificity protein kinase clk2 0.0161 0.1054 0.1242
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0492 0.0532
Echinococcus granulosus tyrosine protein kinase 0.0292 0.2398 0.2398
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0141 0.0857 0.1009
Onchocerca volvulus 0.0076 0.0192 0.0371
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0079 0.0217 0.0255
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Brugia malayi Variant SH3 domain containing protein 0.0066 0.0085 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0857 0.1009
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0299 0.0337
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0161 0.1054 0.1038
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0241 0.187 0.2022
Trypanosoma cruzi casein kinase, putative 0.0115 0.0587 0.0663
Schistosoma mansoni serine/threonine protein kinase 0.089 0.8491 1
Trypanosoma cruzi cdc2-related kinase 3 0.089 0.8491 1
Schistosoma mansoni tyrosine kinase 0.0458 0.4088 0.4815
Loa Loa (eye worm) TK protein kinase 0.0272 0.2192 0.2371
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0079 0.0217 0.0225
Brugia malayi hypothetical protein 0.0106 0.0492 0.0532
Loa Loa (eye worm) hypothetical protein 0.0212 0.1578 0.1707
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0217 0.024
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0085 0.0282 0.0332
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0356 0.3047 0.3296
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Plasmodium falciparum calcium-dependent protein kinase 2 0.0107 0.0506 0.035
Giardia lamblia Kinase, NEK 0.0143 0.0873 0.0819
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0089 0.0322 0.0155
Loa Loa (eye worm) hypothetical protein 0.0125 0.0695 0.0752
Brugia malayi Kinase associated domain 1 family protein 0.0104 0.0474 0.0512
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.089 0.8491 1
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0085 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Loa Loa (eye worm) SRC-1 0.0266 0.2125 0.2299
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0498 0.0572
Brugia malayi Cyclin, N-terminal domain containing protein 0.0076 0.0193 0.0209
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0646 0.601 0.6501
Leishmania major protein kinase A catalytic subunit isoform 2 0.0079 0.0217 0.0028
Echinococcus multilocularis casein kinase I alpha 0.0115 0.0587 0.0692
Trichomonas vaginalis AGC family protein kinase 0.0152 0.097 0.1128
Brugia malayi map kinase activated protein kinase protein 2 0.0406 0.3554 0.3844
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0211 0.1563 0.1563
Loa Loa (eye worm) hypothetical protein 0.0106 0.0492 0.0532
Loa Loa (eye worm) AUR protein kinase 0.0152 0.097 0.1049
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0498 0.0572
Plasmodium vivax tyrosine kinase-like protein, putative 0.0087 0.03 0.0281
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0171 0.1157 0.1336
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Leishmania major protein kinase, putative 0.0161 0.1054 0.1038
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0391 0.0446
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.006 0.0026 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.009 0.0328 0.0355
Loa Loa (eye worm) hypothetical protein 0.0101 0.0444 0.0481
Brugia malayi Protein kinase domain containing protein 0.0221 0.1674 0.181
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0166 0.1111 0.1282
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0087 0.0305 0.033
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.006 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.012 0.0644 0.0696
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0115 0.0587 0.0635
Plasmodium vivax serine/threonine kinase-1, putative 0.0161 0.1054 0.1176
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0217 0.0255
Schistosoma mansoni kinase 0.0201 0.1461 0.1721
Echinococcus granulosus casein kinase I delta 0.0115 0.0587 0.0587
Echinococcus multilocularis growth factor receptor bound protein 2 0.0096 0.0392 0.0461
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0211 0.1563 0.1841
Loa Loa (eye worm) hypothetical protein 0.0126 0.0697 0.0754
Loa Loa (eye worm) TK/EPH protein kinase 0.0131 0.0754 0.0816
Trypanosoma brucei Casein kinase II 0.0106 0.0498 0.0368
Trichomonas vaginalis STE family protein kinase 0.0092 0.0352 0.04
Echinococcus multilocularis rac serine:threonine kinase 0.0171 0.1157 0.1363
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0092 0.0356 0.0385
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0085 0.0282 0.0332
Loa Loa (eye worm) hypothetical protein 0.0852 0.8105 0.8767
Loa Loa (eye worm) hypothetical protein 0.0262 0.2089 0.2259
Loa Loa (eye worm) hypothetical protein 0.0085 0.0282 0.0305
Trichomonas vaginalis CAMK family protein kinase 0.0225 0.1712 0.2005
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0107 0.0506 0.0547
Echinococcus multilocularis cyclin dependent kinase 1 0.089 0.8491 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0697 0.0754
Leishmania major protein kinase, putative 0.0161 0.1054 0.1038
Trichomonas vaginalis CMGC family protein kinase 0.0161 0.1054 0.1228
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.1163 0.137
Entamoeba histolytica protein kinase domain containing protein 0.0092 0.0351 0.0414
Schistosoma mansoni protein kinase 0.0152 0.097 0.1142
Trichomonas vaginalis cyclin B, putative 0.0076 0.0193 0.0213
Echinococcus multilocularis mitogen activated protein kinase 14 0.0166 0.1111 0.1309
Trypanosoma brucei rac serine-threonine kinase, putative 0.0308 0.2559 0.2851
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0086 0.0292 0.0119
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0095 0.0387 0.0233
Entamoeba histolytica casein kinase 1, putative 0.0115 0.0587 0.0692
Schistosoma mansoni ephrin receptor 0.0064 0.0069 0.0082
Trypanosoma cruzi cyclin 6, putative 0.0076 0.0193 0.0198
Loa Loa (eye worm) CDC7 protein kinase 0.0096 0.0391 0.0423
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0795 0.0922
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0161 0.1054 0.1215
Echinococcus multilocularis PAK box P21 Rho binding 0.007 0.0127 0.0149
Loa Loa (eye worm) AGC/NDR protein kinase 0.0175 0.1203 0.1301
Schistosoma mansoni nephrin 0.0123 0.067 0.0789
Echinococcus granulosus insulin receptor 0.0458 0.4088 0.4088
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0121 0.0654 0.077
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0406 0.3554 0.3554
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0164 0.1086 0.1213
Brugia malayi casein kinase 1, delta 0.0115 0.0587 0.0635
Onchocerca volvulus 0.0495 0.4462 0.8615
Schistosoma mansoni titin 0.0076 0.0189 0.0222
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0238 0.1843 0.217
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0079 0.0217 0.0028
Onchocerca volvulus 0.0115 0.0587 0.1134
Trypanosoma brucei polo-like protein kinase 0.0087 0.0299 0.0127
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0104 0.0472 0.0472
Entamoeba histolytica protein kinase, putative 0.0092 0.0351 0.0414
Entamoeba histolytica protein kinase domain containing protein 0.0135 0.0795 0.0936
Leishmania major protein kinase, putative 0.0152 0.097 0.0936
Echinococcus multilocularis serine threonine protein kinase 0.0217 0.1628 0.1917
Loa Loa (eye worm) TK/ABL protein kinase 0.0317 0.2647 0.2863
Echinococcus multilocularis tyrosine protein kinase 0.0292 0.2398 0.2824
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0095 0.0387 0.0419
Echinococcus multilocularis non lysosomal glucosylceramidase 0.0251 0.198 0.2331
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0654 0.0756
Brugia malayi Protein kinase domain containing protein 0.0171 0.1163 0.1258
Plasmodium vivax serine/threonine protein kinase, putative 0.0089 0.0322 0.0306
Echinococcus granulosus mitogen activated protein kinase 3 0.009 0.0328 0.0328
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0107 0.0506 0.0525
Trypanosoma brucei SNF1-related protein kinases, putative 0.0095 0.0387 0.0233
Echinococcus multilocularis serine:threonine protein kinase 0.012 0.0644 0.0758
Trichomonas vaginalis AGC family protein kinase 0.0152 0.097 0.1128
Loa Loa (eye worm) hypothetical protein 0.0101 0.0444 0.0481
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.009 0.0328 0.0162
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0152 0.097 0.1142
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0225 0.1712 0.1852
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0328 0.0372
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0152 0.097 0.1142
Brugia malayi Protein kinase domain containing protein 0.0067 0.0101 0.0109
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0115 0.0587 0.0635
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0087 0.0305 0.033
Brugia malayi Protein kinase domain containing protein 0.012 0.0644 0.0696
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0087 0.0305 0.0305
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.0387 0.0456
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0161 0.1054 0.1215
Schistosoma mansoni protein kinase 0.0092 0.0352 0.0414
Echinococcus granulosus casein kinase I alpha 0.0115 0.0587 0.0587
Trichomonas vaginalis AGC family protein kinase 0.0175 0.1203 0.1404
Schistosoma mansoni tyrosine kinase 0.0144 0.0883 0.104
Schistosoma mansoni tyrosine kinase 0.0458 0.4088 0.4815
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0076 0.0194 0.0229
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.025 0.1967 0.1967
Echinococcus multilocularis N chimaerin 0.0092 0.0356 0.0419
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.009 0.0328 0.0357
Onchocerca volvulus 0.0076 0.0189 0.0365
Trichomonas vaginalis CAMK family protein kinase 0.012 0.0644 0.0744
Echinococcus granulosus cyclin dependent kinase 5 0.089 0.8491 0.8491
Echinococcus multilocularis NCK adaptor protein 0.0098 0.0412 0.0486
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0096 0.0392 0.0461
Entamoeba histolytica protein kinase, putative 0.0308 0.2559 0.3014
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0406 0.3554 0.4185
Brugia malayi SH2 domain containing protein 0.0238 0.1843 0.1993
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0129 0.0728 0.0645
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0079 0.0217 0.0182
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0963 0.9245 1
Trichomonas vaginalis STE family protein kinase 0.0143 0.0873 0.1014
Echinococcus granulosus calcium activated potassium channel 0.0142 0.0859 0.0859
Entamoeba histolytica protein kinase, putative 0.0095 0.0386 0.0454
Plasmodium falciparum serine/threonine protein kinase, putative 0.0152 0.097 0.091
Entamoeba histolytica protein kinase, putative 0.0107 0.0506 0.0596
Onchocerca volvulus 0.0118 0.0619 0.1194
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.1034 0.1218
Echinococcus granulosus protein kinase shaggy 0.0135 0.0795 0.0795
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.012 0.0644 0.0696
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0161 0.1054 0.1215
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0492 0.0532
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0416 0.3655 0.3655
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0159 0.1034 0.1034
Plasmodium vivax protein kinase Crk2 0.089 0.8491 1
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0089 0.0322 0.0348
Brugia malayi Cyclin, N-terminal domain containing protein 0.0076 0.0193 0.0209
Brugia malayi Protein kinase c protein 2 0.0114 0.0581 0.0629
Echinococcus multilocularis casein kinase ii subunit alpha 0.0106 0.0498 0.0587
Entamoeba histolytica protein kinase, putative 0.0089 0.0322 0.0379
Brugia malayi Protein kinase domain containing protein 0.0089 0.0322 0.0348
Brugia malayi Protein kinase domain containing protein 0.0615 0.5692 0.6157
Brugia malayi Protein kinase domain containing protein 0.0461 0.4118 0.4455
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0156 0.1004 0.1086
Schistosoma mansoni serine/threonine protein kinase 0.0406 0.3554 0.4185
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Brugia malayi Protein kinase domain containing protein 0.0188 0.1329 0.1437
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0859 0.1012
Entamoeba histolytica p21-activated kinase 0.0099 0.0423 0.0499
Loa Loa (eye worm) hypothetical protein 0.0096 0.0392 0.0424
Echinococcus granulosus raf serine:threonine protein kinase 0.0083 0.0262 0.0262
Echinococcus multilocularis tyrosine protein kinase shark 0.0323 0.271 0.3192
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0079 0.0217 0.0217
Echinococcus granulosus Immunoglobulin 0.0085 0.0282 0.0282
Echinococcus granulosus tyrosine protein kinase Blk 0.0227 0.1734 0.1734
Brugia malayi Cam kinase protein 1 0.0107 0.0506 0.0547
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0231 0.1767 0.1767
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0363 0.3121 0.6027
Echinococcus multilocularis casein kinase I alpha 0.0115 0.0587 0.0692
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2559 0.3003
Leishmania major casein kinase II, putative 0.0106 0.0498 0.0368
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0266 0.2125 0.2503
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0492 0.0532
Loa Loa (eye worm) TK/FAK protein kinase 0.057 0.5228 0.5655
Schistosoma mansoni protein kinase 0.007 0.0127 0.0149
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0092 0.0351 0.038
Trichomonas vaginalis cyclins, putative 0.0076 0.0193 0.0213
Giardia lamblia Kinase, AGC AKT 0.0123 0.0675 0.058
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0446 0.3966 0.4672
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0181 0.1263 0.1487
Echinococcus granulosus cGMP dependent protein kinase 0.0141 0.0857 0.0857
Loa Loa (eye worm) hypothetical protein 0.0121 0.0651 0.0704
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2559 0.3003
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0587 0.0692
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0075 0.0175 0.0175
Trypanosoma cruzi cdc2-related kinase 1 0.089 0.8491 1
Entamoeba histolytica protein kinase, putative 0.0092 0.0352 0.0414
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0152 0.0963 0.1134
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0079 0.0217 0.0028
Echinococcus granulosus dual specificity 0.0092 0.0351 0.0351
Echinococcus multilocularis dual specificity 0.0092 0.0351 0.0414
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0152 0.097 0.1075
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0461 0.4118 0.4455
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.1034 0.1218
Trichomonas vaginalis cyclins, putative 0.0076 0.0193 0.0213
Schistosoma mansoni tyrosine kinase 0.0089 0.0322 0.038
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0115 0.0587 0.0635
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0387 0.0441
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0188 0.1329 0.1437
Echinococcus granulosus Protein kinase C brain isozyme 0.0252 0.1984 0.1984
Giardia lamblia Kinase, PLK 0.0087 0.0299 0.0127
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.1203 0.1417
Leishmania major protein kinase A catalytic subunit isoform 1 0.0079 0.0217 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0387 0.0456
Loa Loa (eye worm) hypothetical protein 0.0104 0.0474 0.0512
Echinococcus granulosus cGMP dependent protein kinase 1 0.0141 0.0857 0.0857
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0135 0.0795 0.0725
Loa Loa (eye worm) hypothetical protein 0.0244 0.1906 0.2062
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0492 0.0532

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 20 nM Inhibition of bile acid beta-glucosidase activity of human liver GBA2 ChEMBL. 17848577

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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