Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | phosphoglycerate kinase 1 | 0.0197 | 0.4094 | 0.406 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0049 | 0.0936 | 0.1203 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0008 | 0.0058 | 0.0059 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0017 | 0.0256 | 0.0356 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.011 | 0.0268 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0047 | 0.00000000015732 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0324 | 0.0455 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.006 | 0.1166 | 0.1518 |
Brugia malayi | hypothetical protein | 0.0149 | 0.3063 | 0.5138 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.007 | 0.0011 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0013 | 0.0158 | 0.017 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0381 | 0.0325 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0047 | 0.00000000015732 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0058 | 0.0059 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0472 | 0.0708 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0114 | 0.2319 | 0.5628 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1163 | 0.189 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.1163 | 0.2781 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0472 | 0.1026 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0017 | 0.0256 | 0.0271 |
Entamoeba histolytica | phosphoglycerate kinase, putative | 0.0197 | 0.4094 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0256 | 0.0271 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.0799 | 0.1284 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0324 | 0.0455 |
Onchocerca volvulus | Huntingtin homolog | 0.0142 | 0.2915 | 0.9509 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0017 | 0.0256 | 0.0489 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.0472 | 0.0708 |
Chlamydia trachomatis | phosphoglycerate kinase | 0.0197 | 0.4094 | 1 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.007 | 0.0011 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0043 | 0.0799 | 0.1416 |
Echinococcus granulosus | smad | 0.0009 | 0.007 | 0.0011 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0008 | 0.0058 | 0.0059 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0021 | 0.0324 | 0.0714 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0378 | 0.0318 |
Giardia lamblia | Phosphoglycerate kinase | 0.0197 | 0.4094 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0063 | 0.1231 | 0.3008 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0256 | 0.0271 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0008 | 0.0058 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.2915 | 0.4886 |
Brugia malayi | MH2 domain containing protein | 0.0126 | 0.2579 | 0.4311 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0126 | 0.2579 | 0.4311 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.099 | 0.1277 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0049 | 0.0936 | 0.1203 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.1315 | 0.1264 |
Loa Loa (eye worm) | RecQ helicase | 0.0025 | 0.0428 | 0.0632 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.005 | 0.0953 | 0.09 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.011 | 0.0088 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0017 | 0.0248 | 0.0605 |
Mycobacterium leprae | conserved hypothetical protein | 0.0023 | 0.0378 | 0.0792 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0025 | 0.0428 | 0.065 |
Trichomonas vaginalis | phosphoglycerate kinase, putative | 0.0197 | 0.4094 | 0.6908 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0022 | 0.0362 | 0.0752 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.007 | 0.0011 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0008 | 0.0058 | 0.0059 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.007 | 0.0011 |
Schistosoma mansoni | phosphoglycerate kinase | 0.0197 | 0.4094 | 0.406 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 0.1315 | 0.1264 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.099 | 0.1277 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0127 | 0.2591 | 0.6296 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.007 | 0.0019 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.007 | 0.0011 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1163 | 0.189 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0023 | 0.0378 | 0.0546 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0017 | 0.0256 | 0.0338 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0472 | 0.0708 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0027 | 0.0472 | 0.1154 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0378 | 0.0792 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0472 | 0.0568 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.011 | 0.0088 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0021 | 0.0324 | 0.0659 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.099 | 0.2308 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0599 | 0.0924 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.1163 | 0.2842 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0043 | 0.0799 | 0.1284 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0021 | 0.0324 | 0.0178 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 0.1315 | 0.2149 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0021 | 0.0324 | 0.0455 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0008 | 0.0058 | 0.0059 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0256 | 0.0271 |
Brugia malayi | hypothetical protein | 0.0052 | 0.099 | 0.1593 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0472 | 0.0708 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0472 | 0.1154 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0082 | 0.1634 | 0.1585 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0114 | 0.2319 | 0.5602 |
Leishmania major | phosphoglycerate kinase B, cytosolic | 0.0197 | 0.4094 | 0.5532 |
Brugia malayi | Inositol-1 | 0.0043 | 0.0799 | 0.1267 |
Toxoplasma gondii | thioredoxin reductase | 0.005 | 0.0953 | 0.2327 |
Onchocerca volvulus | 0.0149 | 0.3063 | 1 | |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0256 | 0.0271 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0474 | 1 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0027 | 0.0472 | 0.1079 |
Brugia malayi | Phosphoglycerate kinase | 0.0072 | 0.1431 | 0.2347 |
Brugia malayi | glutathione reductase | 0.005 | 0.0953 | 0.153 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.005 | 0.0953 | 0.1226 |
Leishmania major | hypothetical protein, conserved | 0.0052 | 0.099 | 0.1277 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0799 | 0.1016 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0017 | 0.0256 | 0.0271 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.002 | 0.0314 | 0.0257 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0197 | 0.4094 | 0.5532 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0114 | 0.2319 | 0.5628 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0799 | 0.1016 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0175 | 0.0161 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0127 | 0.2591 | 0.6296 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.0637 | 0.0582 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0008 | 0.0058 | 0.0059 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0127 | 0.2591 | 0.6296 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0017 | 0.0256 | 0.0199 |
Trichomonas vaginalis | phosphoglycerate kinase, putative | 0.0197 | 0.4094 | 0.6908 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0106 | 0.0048 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.011 | 0.0052 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.03 | 0.0655 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.0637 | 0.0582 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0799 | 0.1016 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.1315 | 0.1264 |
Plasmodium falciparum | thioredoxin reductase | 0.005 | 0.0953 | 0.2216 |
Brugia malayi | hypothetical protein | 0.0142 | 0.2915 | 0.4886 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0027 | 0.0472 | 0.1079 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0472 | 0.0568 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.03 | 0.0655 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0017 | 0.0256 | 0.0199 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0472 | 0.0708 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0082 | 0.1634 | 0.2695 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0072 | 0.1431 | 0.1881 |
Trypanosoma brucei | phosphoglycerate kinase | 0.0197 | 0.4094 | 0.5532 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0126 | 0.2579 | 0.4311 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0472 | 0.0708 |
Treponema pallidum | phosphoglycerate kinase | 0.0197 | 0.4094 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0472 | 0.0708 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0256 | 0.0271 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0038 | 0.0704 | 0.1599 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0637 | 0.0582 |
Onchocerca volvulus | 0.0027 | 0.0472 | 0.1378 | |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0008 | 0.0058 | 0.0142 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0114 | 0.2319 | 0.5628 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0058 | 0.0059 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0256 | 0.0271 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0378 | 0.0792 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0017 | 0.0256 | 0.0271 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0256 | 0.0271 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.007 | 0.0011 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0082 | 0.1634 | 0.1585 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0023 | 0.0378 | 0.0922 |
Loa Loa (eye worm) | glutathione reductase | 0.005 | 0.0953 | 0.153 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.099 | 0.2308 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0014 | 0.0175 | 0.0219 |
Brugia malayi | TAR-binding protein | 0.0067 | 0.1315 | 0.2149 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0017 | 0.0256 | 0.0489 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.03 | 0.0655 |
Leishmania major | mitochondrial DNA polymerase beta | 0.035 | 0.7354 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.035 | 0.7354 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0378 | 0.0922 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0324 | 0.0455 |
Schistosoma mansoni | smad | 0.0009 | 0.007 | 0.0011 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0023 | 0.0378 | 0.0846 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0047 | 0.00000000015732 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0062 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0472 | 0.0708 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0381 | 0.0325 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0027 | 0.0472 | 0.0708 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0114 | 0.2319 | 0.5628 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.099 | 0.2308 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.0799 | 0.0746 |
Plasmodium falciparum | thioredoxin reductase | 0.0017 | 0.0256 | 0.0489 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0043 | 0.0799 | 0.1952 |
Leishmania major | phosphoglycerate kinase C, glycosomal | 0.0197 | 0.4094 | 0.5532 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0017 | 0.0256 | 0.0545 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0008 | 0.0058 | 0.0059 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.0378 | 0.0438 |
Plasmodium vivax | glutathione reductase, putative | 0.005 | 0.0953 | 0.2216 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0013 | 0.0158 | 0.017 |
Plasmodium falciparum | glutathione reductase | 0.005 | 0.0953 | 0.2216 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0017 | 0.0256 | 0.0624 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.007 | 0.0011 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0072 | 0.1431 | 0.1881 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0072 | 0.1431 | 0.1881 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.007 | 0.0019 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0472 | 0.0708 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0175 | 0.0161 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0166 | 0.342 | 0.4608 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1163 | 0.1112 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.1163 | 0.1112 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.011 | 0.0052 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.1315 | 0.1264 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0114 | 0.2319 | 0.5628 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.3063 | 0.5138 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0023 | 0.0378 | 0.0318 |
Brugia malayi | Thioredoxin reductase | 0.005 | 0.0953 | 0.153 |
Schistosoma mansoni | hypothetical protein | 0.0474 | 1 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0472 | 0.0568 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0472 | 0.1154 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0027 | 0.0472 | 0.0708 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0008 | 0.0058 | 0.0142 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0025 | 0.0428 | 0.065 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.007 | 0.0019 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.0799 | 0.1284 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0058 | 0.0059 |
Brugia malayi | Phosphoglycerate kinase | 0.0197 | 0.4094 | 0.6902 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.011 | 0.0088 |
Brugia malayi | Smad1 | 0.0009 | 0.007 | 0.0019 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0062 | 0.0004 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0596 | 0.0541 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.005 | 0.0953 | 0.09 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.005 | 0.0953 | 0.2262 |
Plasmodium vivax | phosphoglycerate kinase, putative | 0.0197 | 0.4094 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0008 | 0.0058 | 0.0019 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0062 | 0.0004 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.007 | 0.0019 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0936 | 0.1203 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0038 | 0.0704 | 0.1649 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0017 | 0.0252 | 0.0481 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0047 | 0.00000000015732 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.0256 | 0.0338 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.0799 | 0.0746 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0058 | 0.0059 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.011 | 0.0052 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0043 | 0.0799 | 0.1952 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0027 | 0.0472 | 0.0708 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1163 | 0.1112 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0256 | 0.0271 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0043 | 0.0799 | 0.0746 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.011 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.2915 | 0.4886 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0324 | 0.0455 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 0.1315 | 0.2149 |
Loa Loa (eye worm) | inositol-1 | 0.0043 | 0.0799 | 0.1267 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.007 | 0.0019 |
Echinococcus multilocularis | bloom syndrome protein | 0.0025 | 0.0428 | 0.0372 |
Mycobacterium leprae | Probable phosphoglycerate kinase Pgk | 0.0197 | 0.4094 | 1 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.011 | 0.0052 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0381 | 0.0325 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.011 | 0.0052 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0127 | 0.2591 | 0.6274 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0106 | 0.0081 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0027 | 0.0472 | 0.0708 |
Leishmania major | trypanothione reductase | 0.005 | 0.0953 | 0.1226 |
Mycobacterium ulcerans | glutaminase | 0.0282 | 0.5906 | 1 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0043 | 0.0799 | 0.0746 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.001 | 0.011 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.099 | 0.1593 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 0.1315 | 0.2149 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.1315 | 0.1264 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0106 | 0.0048 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.1163 | 0.1515 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.007 | 0.0011 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.1163 | 0.1112 |
Wolbachia endosymbiont of Brugia malayi | phosphoglycerate kinase | 0.0197 | 0.4094 | 1 |
Onchocerca volvulus | 0.0033 | 0.0596 | 0.1791 | |
Trichomonas vaginalis | mercuric reductase, putative | 0.0017 | 0.0256 | 0.0356 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0008 | 0.0058 | 0.0059 |
Echinococcus multilocularis | phosphoglycerate kinase 1 | 0.0197 | 0.4094 | 0.406 |
Entamoeba histolytica | recQ family helicase, putative | 0.0014 | 0.0175 | 0.0428 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0017 | 0.0256 | 0.0338 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0017 | 0.0256 | 0.0271 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0071 | 0.1392 | 0.1342 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.011 | 0.0088 |
Toxoplasma gondii | phosphoglycerate kinase PGKI | 0.0197 | 0.4094 | 1 |
Echinococcus multilocularis | smad | 0.0009 | 0.007 | 0.0011 |
Loa Loa (eye worm) | glutaminase 2 | 0.0282 | 0.5906 | 1 |
Toxoplasma gondii | phosphoglycerate kinase PGKII | 0.0197 | 0.4094 | 1 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0082 | 0.1634 | 0.1585 |
Plasmodium vivax | thioredoxin reductase, putative | 0.005 | 0.0953 | 0.2216 |
Brugia malayi | RNA binding protein | 0.0067 | 0.1315 | 0.2149 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0017 | 0.0256 | 0.0624 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.035 | 0.7354 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.1315 | 0.1264 |
Mycobacterium ulcerans | phosphoglycerate kinase | 0.0197 | 0.4094 | 0.6902 |
Trichomonas vaginalis | glutaminase, putative | 0.0282 | 0.5906 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0166 | 0.342 | 0.4608 |
Trypanosoma brucei | trypanothione reductase | 0.005 | 0.0953 | 0.1226 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0062 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.2612 | 0.4367 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.035 | 0.7354 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0.0047 | 0.00000000015732 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.03 | 0.0655 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0047 | 0.00000000015732 |
Mycobacterium tuberculosis | Probable phosphoglycerate kinase Pgk | 0.0197 | 0.4094 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0017 | 0.0256 | 0.0271 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0378 | 0.0318 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0021 | 0.0324 | 0.0659 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0637 | 0.0582 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0166 | 0.342 | 0.4608 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.0596 | 0.092 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0072 | 0.1431 | 0.1881 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0023 | 0.0378 | 0.0922 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.011 | 0.0268 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.007 | 0.0019 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.007 | 0.0019 |
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 0.1315 | 0.1264 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1634 | 0.2695 |
Onchocerca volvulus | Huntingtin homolog | 0.0142 | 0.2915 | 0.9509 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0256 | 0.0271 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.099 | 0.2417 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0197 | 0.4094 | 0.5532 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0184 | 0.382 | 0.9323 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0062 | 0.0004 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0017 | 0.0256 | 0.0338 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.007 | 0.0011 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0103 | 0.0077 |
Mycobacterium tuberculosis | Probable reductase | 0.0114 | 0.2319 | 0.5628 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0025 | 0.0428 | 0.0632 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.007 | 0.0011 |
Trypanosoma brucei | phosphoglycerate kinase, putative | 0.0072 | 0.1431 | 0.1881 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 0.1315 | 0.2149 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0017 | 0.0256 | 0.0489 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0472 | 0.0708 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0043 | 0.0799 | 0.1267 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0017 | 0.0256 | 0.0199 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.007 | 0.0011 |
Schistosoma mansoni | glutaminase | 0.0282 | 0.5906 | 0.5882 |
Trypanosoma cruzi | 3-phosphoglycerate kinase, glycosomal | 0.0072 | 0.1431 | 0.1881 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0017 | 0.0256 | 0.0367 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1163 | 0.189 |
Loa Loa (eye worm) | thioredoxin reductase | 0.005 | 0.0953 | 0.153 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0.0047 | 0.00000000015732 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0472 | 0.1026 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.4094 | 0.6902 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0052 | 0.099 | 0.1277 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0017 | 0.0256 | 0.0489 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0072 | 0.1431 | 0.1881 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0378 | 0.0546 |
Echinococcus granulosus | bloom syndrome protein | 0.0025 | 0.0428 | 0.0372 |
Brugia malayi | glutaminase DH11.1 | 0.0282 | 0.5906 | 1 |
Toxoplasma gondii | propionate-CoA ligase | 0.0008 | 0.0058 | 0.0142 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0256 | 0.0271 |
Loa Loa (eye worm) | glutaminase | 0.0282 | 0.5906 | 1 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0936 | 0.1203 |
Schistosoma mansoni | phosphoglycerate kinase | 0.0197 | 0.4094 | 0.406 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.0596 | 0.092 |
Plasmodium falciparum | phosphoglycerate kinase | 0.0197 | 0.4094 | 1 |
Onchocerca volvulus | 0.0082 | 0.1634 | 0.5244 | |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0324 | 0.0455 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0799 | 0.1016 |
Toxoplasma gondii | hypothetical protein | 0.0056 | 0.1091 | 0.2663 |
Plasmodium falciparum | glutathione reductase | 0.0017 | 0.0256 | 0.0489 |
Trypanosoma brucei | phosphoglycerate kinase | 0.0072 | 0.1431 | 0.1881 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0023 | 0.0378 | 0.0438 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0256 | 0.0271 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0047 | 0.00000000015732 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0008 | 0.0058 | 0.0142 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0175 | 0.0161 |
Trypanosoma brucei | phosphoglycerate kinase | 0.0197 | 0.4094 | 0.5532 |
Mycobacterium ulcerans | hypothetical protein | 0.0184 | 0.382 | 0.6433 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0256 | 0.0271 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 28617 nM | Inhibition of FAAH in rat brain membrane assessed as [3H]anandamide hydrolysis | ChEMBL. | 18507372 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.