Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.2848 | 0.2848 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.2848 | 0.2848 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0181 | 0.4883 | 1 |
Brugia malayi | TAR-binding protein | 0.0135 | 0.2848 | 0.2848 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0104 | 0.1467 | 0.1467 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0079 | 0.0324 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0135 | 0.2848 | 0.2848 |
Echinococcus multilocularis | geminin | 0.0171 | 0.4439 | 0.9027 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.2848 | 0.2848 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.2848 | 0.2848 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.4439 | 0.4439 |
Loa Loa (eye worm) | RNA binding protein | 0.0135 | 0.2848 | 0.2848 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0104 | 0.1467 | 0.1467 |
Echinococcus granulosus | tar DNA binding protein | 0.0135 | 0.2848 | 0.5536 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0079 | 0.0324 | 0.5 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0079 | 0.0324 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0135 | 0.2848 | 0.2848 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0079 | 0.0324 | 0.5 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0079 | 0.0324 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.2848 | 0.2848 |
Echinococcus granulosus | geminin | 0.0171 | 0.4439 | 0.9027 |
Schistosoma mansoni | glutaminase | 0.0296 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0181 | 0.4883 | 0.4883 |
Brugia malayi | RNA binding protein | 0.0135 | 0.2848 | 0.2848 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0181 | 0.4883 | 0.4883 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0104 | 0.1467 | 0.1467 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.4439 | 0.4439 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0079 | 0.0324 | 0.5 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0079 | 0.0324 | 0.0324 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0181 | 0.4883 | 0.4883 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0079 | 0.0324 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.1467 | 0.1467 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0181 | 0.4883 | 0.4883 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0135 | 0.2848 | 0.2848 |
Loa Loa (eye worm) | glutaminase | 0.0296 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0135 | 0.2848 | 0.5536 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0079 | 0.0324 | 0.5 |
Brugia malayi | Probable ClpP-like protease | 0.0079 | 0.0324 | 0.0324 |
Mycobacterium ulcerans | glutaminase | 0.0296 | 1 | 1 |
Trichomonas vaginalis | glutaminase, putative | 0.0296 | 1 | 0.5 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0079 | 0.0324 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0181 | 0.4883 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0181 | 0.4883 | 0.4883 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0181 | 0.4883 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0324 | 0.0324 |
Loa Loa (eye worm) | glutaminase 2 | 0.0296 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0181 | 0.4883 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.