Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0038 | 0.0158 | 0.0158 |
Trypanosoma cruzi | NADH-ubiquinone oxidoreductase, mitochondrial, putative | 0.0079 | 0.1058 | 0.692 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0038 | 0.0158 | 0.0293 |
Loa Loa (eye worm) | gamma-secretase subunit aph-1 | 0.025 | 0.4813 | 0.4813 |
Brugia malayi | beta-lactamase | 0.0036 | 0.013 | 0.013 |
Loa Loa (eye worm) | AGC/PKC/IOTA protein kinase | 0.0031 | 0.002 | 0.002 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0889 | 0.1644 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0889 | 0.0889 |
Trichomonas vaginalis | AGC family protein kinase | 0.0043 | 0.0275 | 0.1563 |
Entamoeba histolytica | protein kinase, putative | 0.0043 | 0.0275 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0038 | 0.0158 | 0.0293 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0038 | 0.0158 | 0.0158 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0043 | 0.0275 | 0.0275 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.013 | 0.013 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0038 | 0.0158 | 0.0293 |
Brugia malayi | gamma-secretase subunit aph-1 | 0.025 | 0.4813 | 0.4813 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0277 | 0.5409 | 0.5409 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0277 | 0.5409 | 0.5409 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0277 | 0.5409 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0038 | 0.0158 | 0.0158 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0198 | 0.3668 | 0.3668 |
Trichomonas vaginalis | AGC family protein kinase | 0.0043 | 0.0275 | 0.1563 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.004 | 0.0207 | 0.1367 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0038 | 0.0158 | 0.0158 |
Schistosoma mansoni | serine/threonine kinase | 0.0043 | 0.0275 | 0.0509 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0071 | 0.0889 | 0.0889 |
Echinococcus granulosus | Serine/threonine-protein kinase Genghis Khan | 0.0031 | 0.002 | 0.002 |
Entamoeba histolytica | protein kinase, putative | 0.0043 | 0.0275 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0043 | 0.0275 | 1 |
Schistosoma mansoni | unc-13 (munc13) | 0.0037 | 0.0138 | 0.0255 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0043 | 0.0275 | 0.0275 |
Echinococcus multilocularis | unc 13 (munc13) | 0.0037 | 0.0138 | 0.0138 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.0273 | 0.1804 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0038 | 0.0158 | 0.0158 |
Echinococcus granulosus | C2 calcium dependent membrane targeting | 0.0037 | 0.0138 | 0.0138 |
Brugia malayi | ecdysteroid receptor | 0.0038 | 0.0158 | 0.0158 |
Brugia malayi | steroid hormone receptor | 0.0038 | 0.0158 | 0.0158 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.324 | 0.599 |
Toxoplasma gondii | hypothetical protein | 0.0166 | 0.2983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.013 | 0.013 |
Echinococcus granulosus | unc 13 munc13 | 0.0037 | 0.0138 | 0.0138 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0889 | 0.0889 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.013 | 0.013 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0038 | 0.0158 | 0.0158 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0099 | 0.1511 | 0.1511 |
Brugia malayi | Protein kinase domain containing protein | 0.0043 | 0.0275 | 0.0275 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0198 | 0.3668 | 0.3668 |
Toxoplasma gondii | AGC kinase | 0.0043 | 0.0275 | 0.0922 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0273 | 0.1536 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0079 | 0.1077 | 0.1077 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0038 | 0.0158 | 0.0158 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0038 | 0.0158 | 0.0158 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0198 | 0.3668 | 0.3668 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0031 | 0.002 | 0.002 |
Brugia malayi | protein kinase C II. | 0.0079 | 0.1077 | 0.1077 |
Schistosoma mansoni | thyroid hormone receptor | 0.0163 | 0.2906 | 0.5372 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0043 | 0.0275 | 0.0275 |
Echinococcus multilocularis | serine:threonine protein kinase MRCK beta | 0.0031 | 0.002 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.2983 | 0.2983 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0043 | 0.0275 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0487 | 1 | 1 |
Echinococcus granulosus | gamma secretase subunit aph 1 | 0.025 | 0.4813 | 0.4813 |
Brugia malayi | Hr1 repeat family protein | 0.0043 | 0.0275 | 0.0275 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0043 | 0.0275 | 0.0509 |
Echinococcus granulosus | protein kinase C gamma type | 0.0247 | 0.4745 | 0.4745 |
Echinococcus multilocularis | gamma secretase subunit aph 1 | 0.025 | 0.4813 | 0.4813 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0031 | 0.002 | 0.0037 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0231 | 0.441 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0038 | 0.0158 | 0.1047 |
Echinococcus granulosus | protein kinase c iota type | 0.0073 | 0.0939 | 0.0939 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0043 | 0.0275 | 0.0275 |
Onchocerca volvulus | 0.0036 | 0.013 | 0.0861 | |
Echinococcus multilocularis | NADH dehydrogenase (ubiquinone) flavoprotein 1 | 0.0079 | 0.1058 | 0.1058 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0038 | 0.0158 | 0.0158 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase I (chain F) NuoF (NADH-ubiquinone oxidoreductase chain F) | 0.0079 | 0.1058 | 0.2167 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.013 | 0.0241 |
Onchocerca volvulus | 0.0099 | 0.1511 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.1511 | 0.2794 |
Brugia malayi | NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor | 0.0079 | 0.1058 | 0.1058 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0043 | 0.0275 | 0.1082 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0277 | 0.5409 | 1 |
Schistosoma mansoni | NADH-ubiquinone oxidoreductase | 0.0079 | 0.1058 | 0.1955 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.013 | 0.013 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0038 | 0.0158 | 0.0158 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.013 | 0.013 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0247 | 0.4745 | 0.4745 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.013 | 0.0241 |
Echinococcus multilocularis | C2 calcium dependent membrane targeting | 0.0037 | 0.0138 | 0.0138 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.013 | 0.0436 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0038 | 0.0158 | 0.0158 |
Brugia malayi | protein kinase C3,putative | 0.0031 | 0.002 | 0.002 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0275 | 0.0275 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0038 | 0.0158 | 0.0158 |
Trypanosoma cruzi | Aph-1 protein, putative | 0.0097 | 0.147 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0038 | 0.0158 | 0.0158 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0207 | 0.0823 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0889 | 0.0889 |
Schistosoma mansoni | survival motor neuron protein | 0.0099 | 0.1511 | 0.2794 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.2983 | 0.2983 |
Onchocerca volvulus | 0.0031 | 0.0018 | 0.0122 | |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0038 | 0.0158 | 0.0158 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0038 | 0.0158 | 0.0158 |
Trypanosoma brucei | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, putative | 0.0079 | 0.1058 | 0.692 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.013 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0158 | 0.0158 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0889 | 0.0889 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0158 | 0.0158 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0043 | 0.0275 | 0.0275 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0031 | 0.002 | 0.0037 |
Trichomonas vaginalis | NADH-ubiquinone oxidoreductase flavoprotein, putative | 0.0079 | 0.1058 | 1 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0889 | 0.1644 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0043 | 0.0275 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.3668 | 0.3668 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0043 | 0.0275 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0158 | 0.0158 |
Trypanosoma cruzi | NADH-ubiquinone oxidoreductase, mitochondrial, putative | 0.0079 | 0.1058 | 0.692 |
Loa Loa (eye worm) | inward rectifying k channel family protein 1 | 0.0166 | 0.2983 | 0.2983 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0038 | 0.0158 | 0.0158 |
Wolbachia endosymbiont of Brugia malayi | NADH dehydrogenase I subunit F | 0.0079 | 0.1058 | 0.5 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0031 | 0.002 | 0.002 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.013 | 0.013 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0079 | 0.1077 | 0.1077 |
Trichomonas vaginalis | AGC family protein kinase | 0.0043 | 0.0275 | 0.1563 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0043 | 0.0275 | 0.0275 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0038 | 0.0158 | 0.0158 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.013 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0038 | 0.0158 | 0.0158 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0043 | 0.0275 | 0.0509 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0043 | 0.0275 | 0.0275 |
Schistosoma mansoni | thyroid hormone receptor | 0.0163 | 0.2906 | 0.5372 |
Brugia malayi | nuclear receptor NHR-88 | 0.0038 | 0.0158 | 0.0158 |
Trichomonas vaginalis | AGC family protein kinase | 0.0043 | 0.0275 | 0.1563 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0038 | 0.0158 | 0.0158 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0079 | 0.1077 | 0.1077 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0038 | 0.0158 | 0.0158 |
Schistosoma mansoni | gamma-secretase subunit aph-1 | 0.025 | 0.4813 | 0.8899 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0043 | 0.0275 | 0.0509 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0038 | 0.0158 | 0.0158 |
Onchocerca volvulus | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial homolog | 0.0042 | 0.0259 | 0.1713 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.013 | 0.013 |
Echinococcus granulosus | FTZ F1 alpha | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0158 | 0.0158 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0038 | 0.0158 | 0.0158 |
Schistosoma mansoni | nuclear hormone receptor | 0.0038 | 0.0158 | 0.0293 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.2084 | 0.3852 |
Schistosoma mansoni | protein kinase C | 0.0037 | 0.0138 | 0.0255 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0138 | 0.0138 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0043 | 0.0275 | 0.0275 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.013 | 0.013 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0043 | 0.0275 | 0.0275 |
Trichomonas vaginalis | AGC family protein kinase | 0.0043 | 0.0275 | 0.1563 |
Trichomonas vaginalis | AGC family protein kinase | 0.0043 | 0.0275 | 0.1563 |
Brugia malayi | Protein kinase domain containing protein | 0.0043 | 0.0275 | 0.0275 |
Schistosoma mansoni | protein kinase C mu | 0.0031 | 0.002 | 0.0037 |
Trichomonas vaginalis | AGC family protein kinase | 0.0043 | 0.0275 | 0.1563 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0038 | 0.0158 | 0.0293 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0273 | 0.1536 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.013 | 0.013 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0038 | 0.0158 | 0.1047 |
Trichomonas vaginalis | AGC family protein kinase | 0.0043 | 0.0275 | 0.1563 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0038 | 0.0158 | 0.0158 |
Brugia malayi | nuclear hormone receptor | 0.0038 | 0.0158 | 0.0158 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0125 | 0.2084 | 0.2084 |
Brugia malayi | Protein kinase domain containing protein | 0.0031 | 0.002 | 0.002 |
Trichomonas vaginalis | NADH-ubiquinone oxidoreductase flavoprotein, putative | 0.0079 | 0.1058 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0207 | 0.0207 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0487 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0889 | 0.8182 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0207 | 0.0823 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0043 | 0.0275 | 0.0275 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0038 | 0.0158 | 0.0293 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.4332 | 0.4332 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0889 | 0.8182 |
Onchocerca volvulus | 0.0038 | 0.0158 | 0.1047 | |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0205 | 0.3826 | 0.3826 |
Echinococcus multilocularis | protein kinase c iota type | 0.0073 | 0.0939 | 0.0939 |
Trypanosoma cruzi | Aph-1 protein, putative | 0.0097 | 0.147 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0043 | 0.0275 | 0.1563 |
Trypanosoma brucei | Aph-1 protein, putative | 0.0097 | 0.147 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0043 | 0.0275 | 0.1563 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0038 | 0.0158 | 0.0158 |
Brugia malayi | Heterochromatin protein 1 | 0.0071 | 0.0889 | 0.0889 |
Echinococcus multilocularis | geminin | 0.0178 | 0.324 | 0.324 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.013 | 0.013 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0038 | 0.0158 | 0.0293 |
Echinococcus granulosus | NDR protein kinase | 0.0043 | 0.0275 | 0.0275 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0043 | 0.0275 | 0.0275 |
Trichomonas vaginalis | serine/threonine-protein kinase sgk, putative | 0.0042 | 0.0255 | 0.1345 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.013 | 0.013 |
Loa Loa (eye worm) | NADH-ubiquinone oxidoreductase 51 kDa subunit | 0.0079 | 0.1058 | 0.1058 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0079 | 0.1077 | 0.1991 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0487 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0038 | 0.0158 | 0.0158 |
Trichomonas vaginalis | AGC family protein kinase | 0.0043 | 0.0275 | 0.1563 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0158 | 0.0158 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.013 | 0.5 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0038 | 0.0158 | 0.0158 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0038 | 0.0158 | 0.0293 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0043 | 0.0275 | 0.0275 |
Onchocerca volvulus | 0.0037 | 0.0138 | 0.0913 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0038 | 0.0158 | 0.0293 |
Entamoeba histolytica | protein kinase, putative | 0.0043 | 0.0275 | 1 |
Schistosoma mansoni | atypical protein kinase C | 0.0073 | 0.0939 | 0.1736 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.324 | 0.599 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0158 | 0.0158 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.013 | 0.5 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0043 | 0.0275 | 0.0275 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0038 | 0.0158 | 0.0158 |
Onchocerca volvulus | 0.0036 | 0.013 | 0.0861 | |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0163 | 0.2906 | 0.2906 |
Schistosoma mansoni | coup transcription factor | 0.0038 | 0.0158 | 0.0293 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.2983 | 0.2983 |
Onchocerca volvulus | 0.0036 | 0.013 | 0.0861 | |
Trypanosoma brucei | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | 0.0079 | 0.1058 | 0.692 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0038 | 0.0158 | 0.0158 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0038 | 0.0158 | 0.1047 |
Echinococcus granulosus | NADH dehydrogenase ubiquinone flavoprotein 1 | 0.0079 | 0.1058 | 0.1058 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0038 | 0.0158 | 0.0293 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0043 | 0.0275 | 0.0275 |
Brugia malayi | chromobox protein homolog 3 | 0.004 | 0.0207 | 0.0207 |
Brugia malayi | Protein kinase domain containing protein | 0.0043 | 0.0275 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0158 | 0.0158 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0038 | 0.0158 | 0.0158 |
Brugia malayi | C1-like domain containing protein | 0.0031 | 0.002 | 0.002 |
Schistosoma mansoni | unc-13 (munc13) | 0.0037 | 0.0138 | 0.0255 |
Brugia malayi | Protein kinase c protein 2 | 0.0235 | 0.449 | 0.449 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0038 | 0.0158 | 0.0158 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0043 | 0.0275 | 0.0509 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0038 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0043 | 0.0275 | 0.0275 |
Echinococcus granulosus | geminin | 0.0178 | 0.324 | 0.324 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.013 | 0.013 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0125 | 0.2084 | 0.2084 |
Leishmania major | NADH-ubiquinone oxidoreductase, mitochondrial, putative | 0.0079 | 0.1058 | 1 |
Mycobacterium ulcerans | NADH dehydrogenase I subunit F | 0.0079 | 0.1058 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 0 % | Agonist activity at human GPR109A receptor expressed in CHO cells at 100 uM by [35S]GTPgammaS binding assay | ChEMBL. | 18752940 |
Emax (functional) | = 0.36 % | Positive allosteric activity at GPR109A in human HEK cells assessed as shift in EC50 of nicotinic acid at 10 uM pretreated for 30 mins measured after 90 mins by [35S]-GTPgammaS binding assay | ChEMBL. | 22420767 |
Emax (functional) | = 22 % | Positive allosteric activity at GPR109A in human HEK cells at 10 uM pretreated for 30 mins measured after 90 mins by [35S]-GTPgammaS binding assay | ChEMBL. | 22420767 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.