Detailed information for compound 990062

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 432.558 | Formula: C26H32N4O2
  • H donors: 1 H acceptors: 2 LogP: 4.96 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCCNc1nc2cc(OCCCN(C)C)ccc2c2c1C(=O)c1c2cccc1)C
  • InChi: 1S/C26H32N4O2/c1-29(2)14-7-13-27-26-24-23(19-9-5-6-10-20(19)25(24)31)21-12-11-18(17-22(21)28-26)32-16-8-15-30(3)4/h5-6,9-12,17H,7-8,13-16H2,1-4H3,(H,27,28)
  • InChiKey: FFDYOKKWJHHLAV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.115 0.4123
Brugia malayi SET domain containing protein 0.0012 0.0049 0.0049
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0058 0.0821 0.1783
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0049 0.0073
Echinococcus granulosus dna polymerase kappa 0.0078 0.115 0.2061
Onchocerca volvulus 0.0058 0.0821 0.0821
Brugia malayi hypothetical protein 0.0012 0.0049 0.0049
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0016 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.115 0.4123
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.1629 0.5694
Schistosoma mansoni DNA polymerase IV / kappa 0.0024 0.0256 0.0459
Echinococcus granulosus serine threonine protein kinase nrc 0.0049 0.0665 0.1192
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.001 0.0015 0.0027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0256 0.0256
Echinococcus multilocularis nervana 2 0.0047 0.0641 0.1149
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.1827 0.6583
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0124 0.0223
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0123 0.0221
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.115 0.4123
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0027
Echinococcus granulosus chromobox protein 1 0.0072 0.1046 0.1875
Trypanosoma brucei phosphoglycerate kinase 0.0175 0.2767 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0027 0.0027
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0353 0.0353
Onchocerca volvulus Tyrosine kinase homolog 0.014 0.2178 0.2178
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0049 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0027 0.0027
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.001 0.0016 0.0016
Loa Loa (eye worm) AGC/PKN protein kinase 0.0026 0.0279 0.0279
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0027 0.0048
Echinococcus multilocularis serine threonine protein kinase 0.0026 0.0279 0.0501
Loa Loa (eye worm) helicase 0.0012 0.0049 0.0049
Echinococcus granulosus carboxylesterase 5A 0.0345 0.5579 1
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0027 0.0027
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0127 0.0127
Schistosoma mansoni BC026374 protein (S09 family) 0.0058 0.0821 0.1472
Leishmania major trypanothione reductase 0.0047 0.0632 0.2242
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0024 0.0256 0.0925
Schistosoma mansoni topbp1 0.001 0.0016 0.0028
Brugia malayi PHD-finger family protein 0.001 0.0017 0.0017
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0049 0.0665 0.2362
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0064 0.0923 0.33
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0015 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0027 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0049 0.0073
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0123 0.0394
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0049 0.0177
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0016
Echinococcus multilocularis serine:threonine protein kinase 38 0.0026 0.0279 0.0501
Loa Loa (eye worm) hypothetical protein 0.0032 0.0378 0.0378
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0027 0.0048
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0027 0.0048
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0279 0.0583
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0017 0.003
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0124 0.0397
Echinococcus granulosus defective proboscis extension response 0.0009 0.0007 0.0012
Brugia malayi Carboxylesterase family protein 0.0058 0.0821 0.0821
Brugia malayi hypothetical protein 0.001 0.0016 0.0016
Schistosoma mansoni atypical protein kinase C 0.0026 0.0279 0.0501
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0009 0.0007 0.0012
Schistosoma mansoni hypothetical protein 0.0047 0.0643 0.1152
Loa Loa (eye worm) CHromoDomain protein family member 0.0012 0.0049 0.0049
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0124 0.0397
Trichomonas vaginalis DNA polymerase eta, putative 0.0078 0.115 0.251
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0.0017 0.0007
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0027 0.0048
Schistosoma mansoni glutaminase 0.0282 0.4533 0.8125
Schistosoma mansoni vesicular amine transporter 0.0009 0.0007 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0058 0.0821 0.0821
Trypanosoma brucei DNA polymerase eta, putative 0.0129 0.2005 0.7231
Echinococcus granulosus protein kinase c epsilon type 0.0026 0.0279 0.0501
Echinococcus multilocularis nervana 2 0.0047 0.0641 0.1149
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0026 0.0279 0.0501
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0049 0.0073
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0123 0.0394
Schistosoma mansoni smad1 5 8 and 0.0016 0.0127 0.0227
Plasmodium falciparum phd finger protein, putative 0.003 0.0353 0.1228
Echinococcus multilocularis smad 0.0016 0.0127 0.0227
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0027
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0249 0.0249
Plasmodium falciparum DNA repair protein REV1, putative 0.0024 0.0256 0.0876
Onchocerca volvulus 0.0611 1 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0123 0.0394
Trichomonas vaginalis spcc417.12 protein, putative 0.0058 0.0821 0.1783
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.1559 0.1559
Brugia malayi protein kinase C II. 0.0026 0.0279 0.0279
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.015 0.2348 0.2348
Plasmodium vivax phosphoglycerate kinase, putative 0.0175 0.2767 1
Brugia malayi jmjC domain containing protein 0.001 0.0015 0.0015
Plasmodium falciparum heterochromatin protein 1 0.0012 0.0049 0.0124
Schistosoma mansoni hypothetical protein 0.0342 0.5543 0.9935
Onchocerca volvulus Alhambra homolog 0.003 0.0353 0.0353
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.1827 0.6444
Brugia malayi topoisomerase 0.001 0.0016 0.0016
Brugia malayi hypothetical protein 0.0033 0.04 0.04
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0175 0.2767 1
Echinococcus multilocularis chromobox protein 1 0.0072 0.1046 0.1875
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0052 0.0052
Onchocerca volvulus 0.0058 0.0821 0.0821
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0643 0.1152
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0016
Brugia malayi Smad1 0.0016 0.0127 0.0127
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0123 0.0221
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0049 0.0073
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0078 0.115 0.4123
Echinococcus granulosus jumonji domain containing 1A 0.001 0.0015 0.0027
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0049 0.0177
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0027 0.0027
Echinococcus granulosus protein kinase c iota type 0.0026 0.0279 0.0501
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0607 0.1087
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0047 0.0641 0.1149
Echinococcus multilocularis phosphoglycerate kinase 1 0.0175 0.2767 0.496
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0458 0.0821
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0124 0.0124
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0353 0.0632
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.1629 0.5863
Brugia malayi ImpB/MucB/SamB family protein 0.0129 0.2005 0.2005
Schistosoma mansoni Smad4 0.0016 0.0127 0.0227
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0548 0.0983
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0123 0.0394
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0353 0.0632
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0124 0.0223
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0016 0.0003
Trypanosoma brucei trypanothione reductase 0.0047 0.0632 0.2242
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0123 0.0394
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0027
Echinococcus multilocularis dual specificity mitogen activated protein 0.0074 0.1092 0.1957
Mycobacterium tuberculosis Conserved hypothetical protein 0.0078 0.115 0.3882
Loa Loa (eye worm) hypothetical protein 0.0058 0.0821 0.0821
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0123 0.0391
Echinococcus multilocularis nibrin 0.001 0.0016 0.0028
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0709 0.2521
Echinococcus granulosus protein kinase C gamma type 0.0026 0.0279 0.0501
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0065 0.0182
Brugia malayi Immunoglobulin I-set domain containing protein 0.015 0.2342 0.2342
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0027 0.0027
Onchocerca volvulus 0.0012 0.0049 0.0049
Loa Loa (eye worm) carboxylesterase 0.0058 0.0821 0.0821
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.0821 0.1472
Brugia malayi Carboxylesterase family protein 0.0345 0.5579 0.5579
Echinococcus multilocularis geminin 0.0342 0.5543 0.9935
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0065 0.0178
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0024 0.0256 0.0925
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0458 0.0821
Schistosoma mansoni phd/f-box containing protein 0.001 0.0015 0.0027
Trypanosoma brucei rac serine-threonine kinase, putative 0.0075 0.11 0.3943
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0027 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0256 0.0876
Brugia malayi Phosphoglycerate kinase 0.0175 0.2767 0.2767
Brugia malayi Hr1 repeat family protein 0.0026 0.0279 0.0279
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0049 0.0088
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0073 0.1062 0.3801
Schistosoma mansoni hypothetical protein 0.0342 0.5543 0.9935
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0049 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0256 0.0876
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0049 0.0088
Brugia malayi ImpB/MucB/SamB family protein 0.0078 0.115 0.115
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0027 0.0048
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0009 0.0007 0.0012
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0123 0.0446
Leishmania major DNA polymerase eta, putative 0.0129 0.2005 0.7231
Brugia malayi MAP kinase sur-1 0.0051 0.0709 0.0709
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0049 0.0073
Giardia lamblia Kinase, STE STE20 0.0074 0.1092 0.3911
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0016 0.0003
Echinococcus multilocularis Immunoglobulin 0.0009 0.0007 0.0012
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0607 0.1087
Trypanosoma brucei unspecified product 0.0054 0.0747 0.2662
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0027 0.0027
Plasmodium falciparum thioredoxin reductase 0.0047 0.0632 0.2242
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0017 0.0061
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0458 0.0821
Trypanosoma cruzi FHA domain containing protein, putative 0.001 0.0016 0.0003
Entamoeba histolytica hypothetical protein 0.0012 0.0049 0.0121
Schistosoma mansoni serine/threonine kinase 0.0026 0.0279 0.0501
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.1629 0.5694
Schistosoma mansoni serine/threonine-protein kinase 0.0051 0.0699 0.1252
Brugia malayi ecdysteroid receptor 0.001 0.0027 0.0027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0027 0.0048
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0709 0.127
Loa Loa (eye worm) hypothetical protein 0.0012 0.0049 0.0049
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0709 0.2521
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0123 0.0394
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0353 0.1275
Onchocerca volvulus 0.0012 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.012 0.1842 0.1842
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0027 0.0048
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0065 0.0182
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0279 0.0501
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0049 0.0665 0.1192
Schistosoma mansoni smad 0.0016 0.0127 0.0227
Loa Loa (eye worm) TK/KIN16 protein kinase 0.015 0.2342 0.2342
Loa Loa (eye worm) hypothetical protein 0.0047 0.0643 0.0643
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0049 0.0073
Brugia malayi Carboxylesterase family protein 0.0058 0.0821 0.0821
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0027
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0026 0.0279 0.0501
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0123 0.0123
Entamoeba histolytica deoxycytidyl transferase, putative 0.0078 0.115 0.4121
Echinococcus multilocularis GPCR, family 2 0.0047 0.0643 0.1152
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0124 0.0223
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.1629 0.5694
Echinococcus granulosus dual specificity mitogen activated protein 0.0074 0.1092 0.1957
Echinococcus granulosus BC026374 protein S09 family 0.0058 0.0821 0.1472
Plasmodium falciparum replication factor C subunit 1, putative 0.001 0.0016 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0027 0.0027
Mycobacterium tuberculosis Probable reductase 0.0107 0.1629 0.5694
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.07 0.249
Loa Loa (eye worm) pigment dispersing factor receptor c 0.015 0.2348 0.2348
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0175 0.2767 0.6091
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0007
Entamoeba histolytica protein kinase, putative 0.0026 0.0279 0.0958
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0709 0.2519
Mycobacterium ulcerans DNA polymerase IV 0.0078 0.115 0.251
Echinococcus multilocularis serine:threonine protein kinase N2 0.0026 0.0279 0.0501
Trypanosoma cruzi DNA damage repair protein, putative 0.0024 0.0256 0.0876
Plasmodium vivax glutathione reductase, putative 0.0047 0.0632 0.2242
Loa Loa (eye worm) hypothetical protein 0.0103 0.1559 0.1559
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0049 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0747 0.2662
Brugia malayi Pax transcription activation domain interacting protein 0.001 0.0016 0.0016
Echinococcus granulosus neuroligin 0.0058 0.0821 0.1472
Echinococcus granulosus Chromo domain 0.0012 0.0049 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0049 0.0073
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0078 0.115 0.251
Brugia malayi Bromodomain containing protein 0.003 0.0353 0.0353
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0607 0.1087
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0643 0.0643
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0279 0.0583
Brugia malayi Protein cec-1. 0.0012 0.0049 0.0049
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0051 0.0699 0.2484
Plasmodium vivax DNA repair protein REV1, putative 0.0024 0.0256 0.0876
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0123 0.0394
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0009 0.0007 0.0012
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0027 0.0027
Brugia malayi chromobox protein homolog 3 0.004 0.0522 0.0522
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0027 0.0048
Schistosoma mansoni thyroid hormone receptor 0.001 0.0027 0.0048
Loa Loa (eye worm) hypothetical protein 0.0009 0.0005 0.0005
Brugia malayi Pax transcription factor protein 2 0.0248 0.3973 0.3973
Echinococcus multilocularis Chromo domain 0.0012 0.0049 0.0088
Echinococcus multilocularis neuroligin 0.0058 0.0821 0.1472
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0123 0.0238
Loa Loa (eye worm) hypothetical protein 0.0058 0.0821 0.0821
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.115 0.4123
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0016
Leishmania major phosphoglycerate kinase C, glycosomal 0.0175 0.2767 1
Echinococcus granulosus serine/threonine protein kinase 0.0051 0.0699 0.1252
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0573 0.1234
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0049 0.0073
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.1629 0.5694
Trichomonas vaginalis STE family protein kinase 0.0074 0.1092 0.2382
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0049 0.0124
Schistosoma mansoni acetylcholinesterase 0.0058 0.0821 0.1472
Echinococcus multilocularis serine:threonine protein kinase N2 0.0026 0.0279 0.0501
Brugia malayi Immunoglobulin I-set domain containing protein 0.0009 0.0007 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0049 0.0073
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0123 0.0394
Echinococcus granulosus dna polymerase eta 0.0129 0.2005 0.3593
Echinococcus granulosus twitchin 0.0013 0.007 0.0126
Trypanosoma brucei phosphoglycerate kinase 0.0064 0.0923 0.33
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0049 0.0073
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0016 0.0028
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0049 0.0121
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0709 0.1534
Loa Loa (eye worm) carboxylesterase 0.0345 0.5579 0.5579
Trypanosoma brucei DNA damage repair protein, putative 0.0024 0.0256 0.0876
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0027 0.0027
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0058 0.0821 0.1472
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0049 0.0665 0.2362
Brugia malayi p70 ribosomal S6 kinase beta 0.0073 0.1066 0.1066
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0074 0.1092 0.1092
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0175 0.2767 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0123 0.0394
Loa Loa (eye worm) hypothetical protein 0.0026 0.0279 0.0279
Entamoeba histolytica protein kinase, putative 0.0075 0.11 0.3941
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0049 0.0121
Plasmodium vivax heterochromatin protein 1, putative 0.0012 0.0049 0.0124
Mycobacterium ulcerans DNA polymerase IV 0.0078 0.115 0.251
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0127 0.0227
Echinococcus multilocularis acetylcholinesterase 0.0345 0.5579 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0821 0.0821
Loa Loa (eye worm) hypothetical protein 0.0051 0.07 0.07
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0024 0.0255 0.053
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0026 0.0279 0.0501
Schistosoma mansoni hypothetical protein 0.0103 0.1559 0.2794
Echinococcus granulosus Immunoglobulin 0.0009 0.0007 0.0012
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0249 0.0516
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0123 0.0391
Brugia malayi MH2 domain containing protein 0.0241 0.3862 0.3862
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0078 0.115 0.3882
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0049 0.0073
Brugia malayi DKFZp564C0469 protein 0.001 0.0016 0.0016
Leishmania major DNA polymerase kappa, putative 0.0078 0.115 0.4123
Schistosoma mansoni hypothetical protein 0.0012 0.0049 0.0088
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0047 0.0641 0.1149
Trypanosoma cruzi Protein kinase B 0.0051 0.0699 0.2484
Echinococcus granulosus Chromobox protein 3 0.0012 0.0049 0.0088
Brugia malayi Fibronectin type III domain containing protein 0.0009 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0522 0.1121
Plasmodium vivax replication factor C subunit 1, putative 0.001 0.0016 0.0003
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0632 0.1133
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0064 0.0923 0.33
Schistosoma mansoni phosphatidylserine receptor 0.001 0.0015 0.0027
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0643 0.1152
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0709 0.127
Echinococcus multilocularis lysine specific demethylase 6a 0.001 0.0015 0.0027
Echinococcus granulosus Glutaredoxin protein 5 0.0047 0.0641 0.1149
Trichomonas vaginalis AGC family protein kinase 0.0075 0.11 0.24
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0026 0.0279 0.0279
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.115 0.4123
Mycobacterium tuberculosis Carboxylesterase LipT 0.0058 0.0821 0.2639
Loa Loa (eye worm) hypothetical protein 0.0611 1 1
Schistosoma mansoni chromobox protein 0.0012 0.0049 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0709 0.127
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0607 0.0607
Brugia malayi glutathione reductase 0.0047 0.0632 0.0632
Leishmania major hypothetical protein, conserved 0.0051 0.07 0.249
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0027
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0052 0.0052
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0709 0.2561
Brugia malayi Carboxylesterase family protein 0.0058 0.0821 0.0821
Loa Loa (eye worm) pax transcription factor protein 2 0.0248 0.3973 0.3973
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0026 0.0279 0.0501
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0709 0.1534
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0123 0.0391
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0123 0.0394
Trichomonas vaginalis chromobox protein, putative 0.0072 0.1046 0.2281
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0027 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.115 0.4123
Schistosoma mansoni DNA helicase recq5 0.001 0.0017 0.003
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0065 0.0182
Schistosoma mansoni chromobox protein 0.0072 0.1046 0.1875
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0124 0.0124
Brugia malayi N-terminal motif family protein 0.0179 0.2825 0.2825
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0012 0.0057 0.0102
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0078 0.115 0.115
Trypanosoma brucei DNA damage repair protein, putative 0.0024 0.0256 0.0876
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0027 0.0027
Leishmania major DNA polymerase eta, putative 0.0076 0.1111 0.3984
Trypanosoma cruzi DNA polymerase eta, putative 0.0129 0.2005 0.7231
Echinococcus granulosus Protein kinase C brain isozyme 0.0026 0.0279 0.0501
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0313 0.0658
Echinococcus multilocularis protein kinase c epsilon type 0.0026 0.0279 0.0501
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0058 0.0821 0.2639
Loa Loa (eye worm) hypothetical protein 0.0012 0.0049 0.0049
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0049 0.0073
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.1629 0.5694
Brugia malayi Calcitonin receptor-like protein seb-1 0.015 0.2348 0.2348
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.1827 0.6444
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.07 0.249
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.001 0.0015 0.0027
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.115 0.4123
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0279 0.0583
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0123 0.0394
Schistosoma mansoni chromobox protein 0.0072 0.1046 0.1875
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0643 0.1152
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0098 0.1488 0.2667
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0026 0.0279 0.0279
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0049 0.0073
Brugia malayi Heterochromatin protein 1 0.0072 0.1046 0.1046
Loa Loa (eye worm) acetylcholinesterase 1 0.0345 0.5579 0.5579
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0123 0.0394
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0607 0.1087
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0127 0.0227
Entamoeba histolytica hypothetical protein 0.0073 0.1062 0.3801
Brugia malayi jmjC domain containing protein 0.001 0.0015 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0123 0.0394
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0123 0.0394
Trichomonas vaginalis STE family protein kinase 0.0074 0.1092 0.2382
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0118 0.0425
Loa Loa (eye worm) glutaminase 2 0.0282 0.4533 0.4533
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0201 0.0676
Brugia malayi MH1 domain containing protein 0.0009 0.0005 0.0005
Echinococcus granulosus acetylcholinesterase 0.0345 0.5579 1
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0027 0.0027
Schistosoma mansoni DNA polymerase eta 0.0129 0.2005 0.3593
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.1062 0.1903
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.001 0.0015 0.0054
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0064 0.0923 0.33
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0345 0.5579 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0027 0.0027
Giardia lamblia Phosphoglycerate kinase 0.0175 0.2767 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0821 0.0821
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0129 0.2005 0.2005
Echinococcus granulosus acetylcholinesterase 0.0345 0.5579 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0049 0.0073
Brugia malayi AF-10 protein 0.001 0.0017 0.0017
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0017 0.0017
Trypanosoma brucei unspecified product 0.0078 0.115 0.4123
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0027 0.0048
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0249 0.0516
Brugia malayi hypothetical protein 0.001 0.0016 0.0016
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0073 0.1066 0.1066
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0233 0.0418
Toxoplasma gondii histone lysine demethylase JMJD6a 0.001 0.0015 0.0054
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0027
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0026 0.0279 0.0279
Echinococcus multilocularis chromobox protein 2 0.0012 0.0049 0.0088
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.115 0.4123
Toxoplasma gondii thioredoxin reductase 0.0047 0.0632 0.2284
Brugia malayi MH1 domain containing protein 0.0009 0.0005 0.0005
Entamoeba histolytica protein kinase, putative 0.0075 0.11 0.3941
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0049 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0256 0.0876
Schistosoma mansoni serine/threonine-protein kinase 0.0051 0.0699 0.1252
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0049 0.0073
Giardia lamblia PHD finger protein 15 0.003 0.0353 0.1225
Leishmania major DNA polymerase kappa, putative 0.0024 0.0256 0.0876
Giardia lamblia Sgs1 DNA helicase, putative 0.001 0.0017 0.0004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0123 0.0391
Echinococcus granulosus smad 0.0016 0.0127 0.0227
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0007
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0127 0.0227
Mycobacterium ulcerans hypothetical protein 0.0024 0.0256 0.0532
Schistosoma mansoni phosphoglycerate kinase 0.0175 0.2767 0.496
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0353 0.1275
Onchocerca volvulus 0.0058 0.0821 0.0821
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0007
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0175 0.2767 1
Echinococcus multilocularis dna polymerase eta 0.0129 0.2005 0.3593
Schistosoma mansoni terminal deoxycytidyl transferase 0.0078 0.115 0.2061
Onchocerca volvulus 0.0058 0.0821 0.0821
Echinococcus multilocularis rac serine:threonine kinase 0.0051 0.0699 0.1252
Entamoeba histolytica PH domain containing protein kinase, putative 0.0051 0.0699 0.2482
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.07 0.253
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0175 0.2767 1
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0017 0.003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0607 0.1087
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0074 0.1092 0.3913
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0074 0.1092 0.3913
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0458 0.0458
Schistosoma mansoni smad1 5 8 and 0.0016 0.0127 0.0227
Brugia malayi Carboxylesterase family protein 0.0345 0.5579 0.5579
Brugia malayi jmjC domain containing protein 0.001 0.0015 0.0015
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0098 0.1488 0.2667
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0124 0.0223
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0027 0.0048
Loa Loa (eye worm) glutathione reductase 0.0047 0.0632 0.0632
Treponema pallidum NADH oxidase 0.0016 0.0123 0.0391
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0027 0.0027
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0256 0.0876
Brugia malayi Phosphoglycerate kinase 0.0064 0.0923 0.0923
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0643 0.0643
Trichomonas vaginalis AGC family protein kinase 0.0075 0.11 0.24
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0027 0.0048
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0026 0.0279 0.0501
Loa Loa (eye worm) hypothetical protein 0.004 0.0522 0.0522
Brugia malayi MH2 domain containing protein 0.0016 0.0127 0.0127
Brugia malayi glutaminase DH11.1 0.0282 0.4533 0.4533
Brugia malayi hypothetical protein 0.0058 0.0821 0.0821
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0607 0.1087
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.07 0.249
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0074 0.1092 0.3913
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0709 0.2521
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0058 0.0821 0.0821
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.115 0.4123
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0049 0.0088
Schistosoma mansoni chromobox protein 0.0012 0.0049 0.0088
Schistosoma mansoni hypothetical protein 0.0047 0.0643 0.1152
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0123 0.0394
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0166 0.0297
Schistosoma mansoni jumonji domain containing protein 0.001 0.0015 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0256 0.0876
Trichomonas vaginalis AGC family protein kinase 0.0075 0.11 0.24
Loa Loa (eye worm) hypothetical protein 0.0345 0.5579 0.5579
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0607 0.1087
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0016 0.0028
Echinococcus granulosus nibrin 0.001 0.0016 0.0028
Leishmania major phosphoglycerate kinase B, cytosolic 0.0175 0.2767 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0123 0.0238
Echinococcus granulosus nervana 2 0.0047 0.0641 0.1149
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.001 0.0015 0.0027
Echinococcus multilocularis neuroglian 0.0012 0.0046 0.0082
Schistosoma mansoni hypothetical protein 0.003 0.0353 0.0632
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0123 0.0238
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0058 0.0821 0.2639
Entamoeba histolytica phosphoglycerate kinase, putative 0.0175 0.2767 1
Echinococcus multilocularis Immunoglobulin 0.0009 0.0007 0.0012
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0049 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0075 0.11 0.24
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.0821 0.1472
Echinococcus granulosus Smad4 0.0016 0.0127 0.0227
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.001 0.0017 0.0007
Trypanosoma brucei phosphoglycerate kinase, putative 0.0064 0.0923 0.33
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0012 0.0049 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0279 0.0501
Schistosoma mansoni hypothetical protein 0.001 0.0017 0.003
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0709 0.2521
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0027 0.0027
Echinococcus granulosus GPCR family 2 0.0047 0.0643 0.1152
Echinococcus granulosus JmjC domain containing protein 4 0.001 0.0015 0.0027
Echinococcus multilocularis jumonji domain containing 1A 0.001 0.0015 0.0027
Trichomonas vaginalis Heterochromatin protein, putative 0.0012 0.0049 0.0073
Trichomonas vaginalis STE family protein kinase 0.0074 0.1092 0.2382
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0632 0.0632
Brugia malayi CHD4 protein 0.0012 0.0049 0.0049
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0017 0.0061
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0049 0.0049
Trypanosoma brucei protein kinase, putative 0.0051 0.0709 0.2521
Echinococcus multilocularis roundabout 2 0.0015 0.0096 0.0172
Echinococcus granulosus neuroglian 0.0012 0.0046 0.0082
Brugia malayi Carboxylesterase family protein 0.0058 0.0821 0.0821
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0175 0.2767 1
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.115 0.4123
Echinococcus multilocularis protein kinase c iota type 0.0026 0.0279 0.0501
Loa Loa (eye worm) nuclear factor I 0.0009 0.0005 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.115 0.4123
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0027
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0017 0.0017
Echinococcus multilocularis para nitrobenzyl esterase 0.0058 0.0821 0.1472
Schistosoma mansoni hypothetical protein 0.0047 0.0643 0.1152
Schistosoma mansoni coup transcription factor 0.001 0.0027 0.0048
Plasmodium falciparum glutathione reductase 0.0047 0.0632 0.2242
Echinococcus granulosus lysine specific demethylase 6a 0.001 0.0015 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0747 0.2662
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.115 0.4123
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0548 0.0983
Trypanosoma brucei unspecified product 0.0054 0.0747 0.2662
Echinococcus granulosus serine:threonine protein kinase N2 0.0026 0.0279 0.0501
Echinococcus multilocularis peregrin 0.003 0.0353 0.0632
Loa Loa (eye worm) hypothetical protein 0.0012 0.0049 0.0049
Brugia malayi Thioredoxin reductase 0.0047 0.0632 0.0632
Brugia malayi steroid hormone receptor 0.001 0.0027 0.0027
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0027 0.0048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0049 0.0073
Loa Loa (eye worm) RecQ helicase 0.0024 0.0249 0.0249
Trypanosoma cruzi DNA polymerase eta, putative 0.0076 0.1111 0.3984
Trichomonas vaginalis AGC family protein kinase 0.0075 0.11 0.24
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0127 0.0227
Loa Loa (eye worm) hypothetical protein 0.0058 0.0821 0.0821
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.1062 0.1903
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0175 0.2767 1
Entamoeba histolytica hypothetical protein 0.0012 0.0049 0.0121
Loa Loa (eye worm) hypothetical protein 0.0345 0.5579 0.5579
Mycobacterium ulcerans carboxylesterase, LipT 0.0058 0.0821 0.1783
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0026 0.0279 0.0501
Loa Loa (eye worm) hypothetical protein 0.0012 0.0057 0.0057
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0632 0.2242
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0027 0.0048
Trypanosoma brucei phosphoglycerate kinase 0.0175 0.2767 1
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0709 0.1534
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0027 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.115 0.4123
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0124 0.0397
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0012 0.0049 0.0088
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0049 0.0049
Echinococcus granulosus chromobox protein 2 0.0012 0.0049 0.0088
Loa Loa (eye worm) hypothetical protein 0.0051 0.0709 0.0709
Schistosoma mansoni nephrin 0.0012 0.0046 0.0082
Echinococcus granulosus roundabout 2 0.0015 0.0096 0.0172
Entamoeba histolytica protein kinase 2, putative 0.0049 0.0665 0.2359
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0049 0.0049
Chlamydia trachomatis phosphoglycerate kinase 0.0175 0.2767 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0353 0.0353
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0017
Echinococcus granulosus FTZ F1 alpha 0.001 0.0027 0.0048
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0015 0.0015
Brugia malayi nuclear hormone receptor 0.001 0.0027 0.0027
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0632 0.1923
Leishmania major DNA damage repair protein, putative 0.0024 0.0256 0.0876
Loa Loa (eye worm) glutaminase 0.0282 0.4533 0.4533
Schistosoma mansoni gliotactin 0.0058 0.0821 0.1472
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0049 0.0088
Echinococcus granulosus peregrin 0.003 0.0353 0.0632
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0078 0.115 0.2061
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0027 0.0048
Schistosoma mansoni protein kinase 0.0074 0.1092 0.1957
Treponema pallidum phosphoglycerate kinase 0.0175 0.2767 1
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0017 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0049 0.0124
Echinococcus multilocularis BC026374 protein (S09 family) 0.0058 0.0821 0.1472
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0096
Plasmodium vivax hypothetical protein, conserved 0.003 0.0353 0.1228
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0522 0.1121
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0709 0.127
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0124 0.0223
Entamoeba histolytica hypothetical protein 0.0073 0.1062 0.3801
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0064 0.0923 0.33
Brugia malayi jmjC domain containing protein 0.001 0.0015 0.0015
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0884 0.0884
Entamoeba histolytica hypothetical protein 0.0012 0.0049 0.0121
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.2825 0.2825
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0007
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0049 0.0073
Trichomonas vaginalis chromobox protein, putative 0.0072 0.1046 0.2281
Brugia malayi MH1 domain containing protein 0.0016 0.0127 0.0127
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0027 0.0048
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0075 0.11 0.24
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.07 0.249
Echinococcus multilocularis phd:f box containing protein 0.001 0.0015 0.0027
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0026 0.0279 0.0501
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0121 0.0385
Entamoeba histolytica hypothetical protein 0.0073 0.1062 0.3801
Echinococcus granulosus replication factor c subunit 1 0.001 0.0016 0.0028
Toxoplasma gondii AGC kinase 0.0073 0.1066 0.3854
Plasmodium falciparum glutathione reductase 0.0016 0.0123 0.0394
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0123 0.0238
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0017 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0327 0.0689
Loa Loa (eye worm) AGC/AKT protein kinase 0.0075 0.11 0.11
Brugia malayi hypothetical protein 0.0051 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0175 0.2767 0.2767
Echinococcus granulosus phosphoglycerate kinase 1 0.0175 0.2767 0.496
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0027 0.0027
Brugia malayi MH2 domain containing protein 0.0016 0.0127 0.0127
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.115 0.4123
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0607 0.0607
Brugia malayi polk-prov protein 0.0024 0.0256 0.0256
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0124 0.0449
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.07 0.249
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0017 0.003
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0256 0.0876
Schistosoma mansoni cell adhesion molecule 0.0012 0.0057 0.0102
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0124 0.0397
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0027 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0049 0.0073
Echinococcus granulosus NDR protein kinase 0.0026 0.0279 0.0501
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0123 0.0394
Echinococcus multilocularis carboxylesterase 5A 0.0345 0.5579 1
Loa Loa (eye worm) transcription factor SMAD2 0.0241 0.3862 0.3862
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0279 0.0501
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0027 0.0048
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0175 0.2767 0.6091
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0027 0.0048
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0124 0.0223
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0049 0.0665 0.1192
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.001 0.0017 0.0061
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0049 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0027 0.0027
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0124 0.0397
Brugia malayi hypothetical protein 0.0073 0.1062 0.1062
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0123 0.0394
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0124 0.0397
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0017 0.003
Onchocerca volvulus 0.0032 0.0378 0.0378
Entamoeba histolytica PH domain containing protein kinase, putative 0.0051 0.0699 0.2482
Brugia malayi PHD-finger family protein 0.003 0.0353 0.0353
Toxoplasma gondii ATPase, AAA family protein 0.001 0.0016 0.0057
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0049 0.0073
Plasmodium falciparum phosphoglycerate kinase 0.0175 0.2767 1
Onchocerca volvulus 0.001 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0049 0.0049
Brugia malayi jmjC domain containing protein 0.0036 0.0458 0.0458
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0709 0.2521
Plasmodium vivax hypothetical protein, conserved 0.001 0.0017 0.0007
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0027 0.0048
Brugia malayi MH1 domain containing protein 0.0016 0.0127 0.0127
Brugia malayi Protein kinase domain containing protein 0.0026 0.0279 0.0279
Echinococcus granulosus bloom syndrome protein 0.0024 0.0249 0.0446
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0175 0.2767 1
Echinococcus multilocularis acetylcholinesterase 0.0345 0.5579 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0027 0.0048
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0124 0.0223
Brugia malayi isocitrate dehydrogenase 0.0016 0.0124 0.0124
Mycobacterium ulcerans phosphoglycerate kinase 0.0175 0.2767 0.6091
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0123 0.0221
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0049 0.0177
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0123 0.0394
Loa Loa (eye worm) AGC/NDR protein kinase 0.0026 0.0279 0.0279
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0123 0.0394
Trichomonas vaginalis glutaminase, putative 0.0282 0.4533 1
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0573 0.1234
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0026 0.0279 0.0279
Brugia malayi hypothetical protein 0.0009 0.0007 0.0007
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0709 0.127
Trichomonas vaginalis AGC family protein kinase 0.0075 0.11 0.24
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0049 0.0088
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0016 0.0003
Brugia malayi nuclear receptor NHR-88 0.001 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0007
Schistosoma mansoni nuclear hormone receptor 0.001 0.0027 0.0048
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.1046 0.1046
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0049 0.0073
Entamoeba histolytica protein kinase, putative 0.0073 0.1066 0.3818
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0279 0.0501
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0049 0.0124
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0123 0.0394
Loa Loa (eye worm) hypothetical protein 0.0015 0.0096 0.0096
Echinococcus multilocularis dna polymerase kappa 0.0078 0.115 0.2061
Loa Loa (eye worm) hypothetical protein 0.0012 0.0049 0.0049
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0123 0.0446
Echinococcus granulosus phd:f box containing protein 0.001 0.0015 0.0027
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0065 0.0109
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.001 0.0016 0.0057
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.0821 0.1472
Mycobacterium ulcerans glutaminase 0.0282 0.4533 1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0012 0.0049 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0027 0.0027
Trichomonas vaginalis hypothetical protein 0.0012 0.0049 0.0073
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0123 0.0238
Brugia malayi Protein kinase domain containing protein 0.0026 0.0279 0.0279
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0279 0.0501
Schistosoma mansoni hypothetical protein 0.0023 0.0233 0.0418
Loa Loa (eye worm) carboxylesterase 0.0058 0.0821 0.0821
Schistosoma mansoni thyroid hormone receptor 0.001 0.0027 0.0048
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0015 0.0015
Giardia lamblia Kinase, AGC PKA 0.0049 0.0665 0.2359
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0127 0.0227
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0076 0.1111 0.4016
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.115 0.4123
Plasmodium falciparum thioredoxin reductase 0.0016 0.0123 0.0394
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0123 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0327 0.0689
Loa Loa (eye worm) hypothetical protein 0.0012 0.0049 0.0049
Echinococcus multilocularis JmjC domain containing protein 4 0.001 0.0015 0.0027
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0709 0.2521
Schistosoma mansoni topbp1 0.001 0.0016 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0049 0.0073
Echinococcus granulosus geminin 0.0342 0.5543 0.9935
Onchocerca volvulus 0.001 0.0027 0.0027
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0643 0.0643
Schistosoma mansoni smad1 5 8 and 0.0016 0.0127 0.0227
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.0923 0.33
Echinococcus multilocularis Smad4 0.0016 0.0127 0.0227
Schistosoma mansoni DNA ligase IV 0.001 0.0016 0.0028
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0709 0.0709
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0249 0.0446
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0017 0.0061
Schistosoma mansoni hypothetical protein 0.0047 0.0643 0.1152
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0124 0.0003
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.1062 0.1903
Schistosoma mansoni DNA helicase recq1 0.001 0.0017 0.003
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0233 0.0418
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0027 0.0048
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0124 0.0397
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0124 0.0449
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0017 0.003
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.015 0.2348 0.2348
Echinococcus granulosus nervana 2 0.0047 0.0641 0.1149
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0747 0.2662
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0078 0.115 0.2061
Loa Loa (eye worm) hypothetical protein 0.0179 0.2825 0.2825
Schistosoma mansoni jumonji domain containing protein 0.0078 0.1152 0.2065
Schistosoma mansoni phosphoglycerate kinase 0.0175 0.2767 0.496
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0458 0.0821
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0709 0.1534
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0573 0.0573
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.1827 0.6444
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0709 0.2521
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0027 0.0027
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.115 0.4123
Onchocerca volvulus 0.0012 0.0049 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.115 0.4123
Loa Loa (eye worm) MH2 domain-containing protein 0.0241 0.3862 0.3862
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0643 0.1152
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0027
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0522 0.0522
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.0923 0.33
Echinococcus multilocularis chromobox protein 1 0.0072 0.1046 0.1875
Schistosoma mansoni hypothetical protein 0.0073 0.1062 0.1903
Trypanosoma cruzi DNA damage repair protein, putative 0.0024 0.0256 0.0876
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0027 0.0048
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0127 0.0127
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0078 0.115 0.2061
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0353 0.0632
Onchocerca volvulus 0.0137 0.2125 0.2125
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0027 0.0048
Echinococcus granulosus chromobox protein 1 0.0072 0.1046 0.1875
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0279 0.0501
Schistosoma mansoni protein phosphatase 2C 0.001 0.0015 0.0027
Giardia lamblia DNA damage repair protein 0.0024 0.0256 0.0873
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0016
Onchocerca volvulus 0.0058 0.0821 0.0821
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0049 0.0088
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0049 0.0073
Onchocerca volvulus 0.0248 0.3973 0.3973
Schistosoma mansoni neuroligin 3 (S09 family) 0.0058 0.0821 0.1472
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0279 0.0501
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0632 0.1133
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0049 0.0124
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0632 0.2242
Echinococcus granulosus para nitrobenzyl esterase 0.0058 0.0821 0.1472
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0027 0.0027
Brugia malayi Protein kinase domain containing protein 0.0075 0.11 0.11
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0007
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0058 0.0821 0.1472
Echinococcus multilocularis Glutaredoxin protein 5 0.0047 0.0641 0.1149
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Brugia malayi jmjC domain containing protein 0.0098 0.1488 0.1488
Giardia lamblia DINP protein human, muc B family 0.0078 0.115 0.4121
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0049 0.0665 0.2362
Trypanosoma brucei chrX additional, unordered contigs 0.0024 0.0256 0.0876
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0049 0.0073
Loa Loa (eye worm) Smad1 0.0016 0.0127 0.0127
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0027 0.0048
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.07 0.249
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0074 0.1092 0.1092
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0027 0.0027

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 5.44 uM Cytotoxicity against human mitoxantrone-sensitive HL60 cells after 72 hrs ChEMBL. 18507368

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 18507368

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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