Detailed information for compound 990629

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 356.368 | Formula: C17H24O8
  • H donors: 5 H acceptors: 6 LogP: -0.18 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1O[C@H](O[C@@H](CC(=O)O)CCc2ccccc2)[C@H]([C@@H]([C@H]1O)O)O
  • InChi: 1S/C17H24O8/c18-9-12-14(21)15(22)16(23)17(25-12)24-11(8-13(19)20)7-6-10-4-2-1-3-5-10/h1-5,11-12,14-18,21-23H,6-9H2,(H,19,20)/t11-,12+,14+,15-,16+,17+/m1/s1
  • InChiKey: HRYIDVZLDQBLFF-FPUJXFPJSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0046 0.0685
Entamoeba histolytica hypothetical protein 0.0043 0.0031 0.0858
Trypanosoma cruzi metacaspase, putative 0.0032 0.0008 0.0113
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0075 0.0093 0.1403
Entamoeba histolytica hypothetical protein 0.0043 0.0031 0.0858
Echinococcus granulosus phosphoglycerate kinase 1 0.0206 0.0348 0.1134
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0008 0.0126
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0096 0.0134 0.2251
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.005 0.0742
Trypanosoma cruzi metacaspase 5, putative 0.0032 0.0008 0.0113
Echinococcus granulosus caspase 2 0.0032 0.0008 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0134 0.1943
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0284 0.4291
Entamoeba histolytica hypothetical protein 0.0043 0.0031 0.0858
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0125 0.0156
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0051 0.0045 0.1283
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.0087 0.1218
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0206 0.0348 1
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0046 0.0595
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0047 0.0037 0.0037
Brugia malayi ImpB/MucB/SamB family protein 0.0064 0.0071 0.0064
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0008 0.0126
Echinococcus granulosus snurportin 1 0.0372 0.0674 0.2216
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0206 0.0348 0.5
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0037 0.1051
Loa Loa (eye worm) hypothetical protein 0.0206 0.0348 0.0431
Onchocerca volvulus 0.0037 0.0018 0.0032
Leishmania major DNA polymerase kappa, putative 0.0072 0.0087 0.1302
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0014 0.0414
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.01 0.0141 0.0446
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0134 0.1943
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0014 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0011 0.0171
Loa Loa (eye worm) hypothetical protein 0.006 0.0064 0.0072
Schistosoma mansoni hypothetical protein 0.01 0.0141 0.0177
Plasmodium vivax metacaspase 1, putative 0.0032 0.0008 0.0035
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0032 0.0008 0.0236
Loa Loa (eye worm) hypothetical protein 0.0047 0.0037 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0008 0.0126
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0032 0.0008 0.0236
Entamoeba histolytica Flap nuclease, putative 0.0031 0.0007 0.0181
Brugia malayi hypothetical protein 0.0043 0.0031 0.0024
Schistosoma mansoni glutaminase 0.033 0.0593 0.0746
Entamoeba histolytica hypothetical protein 0.0043 0.0031 0.0858
Brugia malayi PHD-finger family protein 0.0035 0.0014 0.0007
Trypanosoma brucei phosphoglycerate kinase 0.0206 0.0348 0.5223
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0008 0.0126
Giardia lamblia DINP protein human, muc B family 0.0072 0.0087 0.2333
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.0661 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0014 0.0024
Schistosoma mansoni hypothetical protein 0.0043 0.0031 0.0037
Brugia malayi Importin beta-1 subunit 0.0035 0.0014 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0014 0.0216
Plasmodium falciparum metacaspase 1 0.0032 0.0008 0.0035
Loa Loa (eye worm) RecQ helicase 0.0079 0.01 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0134 0.1943
Brugia malayi RNA, U transporter 1 0.0099 0.014 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.4073 0.7932 1
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0206 0.0348 0.5269
Echinococcus granulosus peregrin 0.0035 0.0014 0.0024
Brugia malayi Cell death protein 3 precursor 0.0032 0.0008 0.0001
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0008 0.0035
Plasmodium falciparum phosphoglycerate kinase 0.0206 0.0348 1
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0038 0.0627
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.005 0.0742
Brugia malayi polk-prov protein 0.0052 0.0047 0.004
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0014 0.0414
Mycobacterium ulcerans hypothetical protein 0.0192 0.0322 0.41
Toxoplasma gondii hypothetical protein 0.0059 0.0061 0.1743
Loa Loa (eye worm) hypothetical protein 0.0179 0.0296 0.0364
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0014 0.0392
Loa Loa (eye worm) apoptosis regulator protein 0.01 0.0141 0.017
Echinococcus multilocularis caspase 2 0.0032 0.0008 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0134 0.202
Trichomonas vaginalis DNA helicase recq1, putative 0.0079 0.01 0.1671
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0014 0.0022
Echinococcus multilocularis chromobox protein 1 0.0084 0.011 0.0343
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0031 0.0078
Trypanosoma brucei DNA polymerase eta, putative 0.0095 0.0131 0.1902
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0206 0.0348 1
Trypanosoma cruzi metacaspase, putative 0.0032 0.0008 0.0113
Echinococcus multilocularis caspase 8 0.0032 0.0008 0.0004
Leishmania major DNA polymerase eta, putative 0.0051 0.0045 0.0666
Loa Loa (eye worm) glutaminase 2 0.033 0.0593 0.0739
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0134 0.1943
Trypanosoma brucei unspecified product 0.0044 0.0032 0.0383
Plasmodium falciparum importin beta, putative 0.0035 0.0014 0.0194
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0206 0.0348 0.5873
Trypanosoma brucei Metacaspase-4 0.0032 0.0008 0.0018
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.01 0.0141 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0038 0.0627
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.0007 0.0095
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0008 0.0126
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0037 0.003
Trypanosoma brucei DNA polymerase IV, putative 0.0096 0.0134 0.1943
Entamoeba histolytica recQ family helicase, putative 0.0053 0.005 0.1407
Loa Loa (eye worm) hypothetical protein 0.0037 0.0018 0.0014
Schistosoma mansoni DNA helicase recq5 0.0047 0.0037 0.0045
Leishmania major DNA polymerase eta, putative 0.0095 0.0131 0.198
Trichomonas vaginalis chromobox protein, putative 0.0084 0.011 0.1852
Plasmodium falciparum phd finger protein, putative 0.0035 0.0014 0.0216
Schistosoma mansoni phosphoglycerate kinase 0.0206 0.0348 0.0438
Schistosoma mansoni caspase-7 (C14 family) 0.0032 0.0008 0.0009
Echinococcus multilocularis dna polymerase eta 0.0095 0.0131 0.0413
Echinococcus multilocularis dna polymerase kappa 0.0096 0.0134 0.0422
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0048 0.004 0.1152
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0008 0.0126
Echinococcus multilocularis Cyclin dependent kinase 2 associated protein 0.1567 0.3018 1
Trypanosoma brucei unspecified product 0.0044 0.0032 0.0383
Trypanosoma cruzi DNA polymerase eta, putative 0.0051 0.0045 0.0666
Loa Loa (eye worm) hypothetical protein 0.0032 0.0008 0.0001
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0032 0.0008 0.0004
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0047 0.0037 0.0098
Echinococcus multilocularis chromobox protein 1 0.0084 0.011 0.0343
Brugia malayi Bloom's syndrome protein homolog 0.0079 0.01 0.0093
Echinococcus multilocularis bloom syndrome protein 0.0079 0.01 0.0308
Brugia malayi jmjC domain containing protein 0.0115 0.0171 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0134 0.1943
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0134 0.1943
Trypanosoma brucei DNA polymerase IV, putative 0.0088 0.0118 0.1704
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0047 0.0617
Trypanosoma brucei metacaspase MCA3 0.0032 0.0008 0.0018
Echinococcus multilocularis snurportin 1 0.0372 0.0674 0.2216
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.01 0.0141 0.0177
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0134 0.202
Trichomonas vaginalis glutaminase, putative 0.033 0.0593 1
Trypanosoma cruzi metacaspase, putative 0.0032 0.0008 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0134 0.1943
Echinococcus granulosus caspase 8 0.0032 0.0008 0.0004
Echinococcus granulosus dna polymerase kappa 0.0096 0.0134 0.0422
Trypanosoma cruzi metacaspase, putative 0.0032 0.0008 0.0113
Brugia malayi glutaminase DH11.1 0.033 0.0593 0.0586
Schistosoma mansoni deleted in oral cancer 1/cdk2-associated protein-like 0.1567 0.3018 0.3804
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0008 0.0126
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0009
Echinococcus multilocularis peregrin 0.0035 0.0014 0.0024
Trypanosoma cruzi DNA polymerase eta, putative 0.0095 0.0131 0.198
Schistosoma mansoni hypothetical protein 0.01 0.0141 0.0177
Loa Loa (eye worm) hypothetical protein 0.0032 0.0008 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0088 0.0102
Entamoeba histolytica deoxycytidyl transferase, putative 0.0064 0.0071 0.2022
Plasmodium falciparum metacaspase-like protein 0.0032 0.0008 0.0035
Schistosoma mansoni DNA helicase recq1 0.0047 0.0037 0.0045
Brugia malayi Phosphoglycerate kinase 0.0075 0.0093 0.0086
Echinococcus granulosus Cyclin dependent kinase 2 associated protein 0.1567 0.3018 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0131 0.0157
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.0284 0.4236
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0045 0.0122
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.0007 0.0202
Brugia malayi ImpB/MucB/SamB family protein 0.0095 0.0131 0.0124
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0014 0.0024
Plasmodium vivax phosphoglycerate kinase, putative 0.0206 0.0348 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.0661 1
Loa Loa (eye worm) hypothetical protein 0.01 0.0141 0.017
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0051
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0206 0.0348 0.5
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0047 0.0037 0.0867
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0032 0.0008 0.0001
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0014 0.0017
Schistosoma mansoni phosphoglycerate kinase 0.0206 0.0348 0.0438
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.011 0.013
Brugia malayi chromobox protein homolog 3 0.0047 0.0038 0.0031
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0064 0.0071 0.0213
Echinococcus granulosus importin subunit beta 1 0.0035 0.0014 0.0022
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0072 0.0087 0.0563
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0048 0.0622
Schistosoma mansoni hypothetical protein 0.01 0.0141 0.0177
Trypanosoma brucei phosphoglycerate kinase 0.0206 0.0348 0.5223
Brugia malayi Protein kinase domain containing protein 0.4073 0.7932 0.793
Echinococcus granulosus chromobox protein 1 0.0084 0.011 0.0343
Trypanosoma cruzi metacaspase 5, putative 0.0032 0.0008 0.0113
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0029 0.0035
Onchocerca volvulus Alhambra homolog 0.0035 0.0014 0.0021
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0075 0.0093 0.1403
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0134 0.202
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.0322 0.9051
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0008 0.0126
Leishmania major metacaspase, putative 0.0032 0.0008 0.0113
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0008 0.0126
Schistosoma mansoni DNA polymerase eta 0.0095 0.0131 0.0164
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0075 0.0093 0.1403
Echinococcus granulosus chromobox protein 1 0.0084 0.011 0.0343
Schistosoma mansoni chromobox protein 0.0084 0.011 0.0138
Loa Loa (eye worm) hypothetical protein 0.1567 0.3018 0.38
Echinococcus granulosus dna polymerase eta 0.0095 0.0131 0.0413
Trichomonas vaginalis DNA polymerase eta, putative 0.0096 0.0134 0.2251
Trypanosoma brucei metacaspase 5, putative 0.0032 0.0008 0.0018
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.0661 1
Trichomonas vaginalis chromobox protein, putative 0.0084 0.011 0.1852
Trypanosoma brucei DNA polymerase IV, putative 0.0096 0.0134 0.1943
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.0007 0.0095
Schistosoma mansoni importin beta-1 0.0035 0.0014 0.0016
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0171 0.0546
Trichomonas vaginalis DNA helicase recq, putative 0.0053 0.005 0.0827
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.01 0.0141 0.0446
Mycobacterium ulcerans phosphoglycerate kinase 0.0206 0.0348 0.4674
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.0661 1
Chlamydia trachomatis phosphoglycerate kinase 0.0206 0.0348 0.5
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0047 0.0037 0.0098
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0064 0.0071 0.0213
Brugia malayi Heterochromatin protein 1 0.0084 0.011 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0047 0.0617
Leishmania major phosphoglycerate kinase C, glycosomal 0.0206 0.0348 0.5269
Echinococcus multilocularis caspase 0.0032 0.0008 0.0004
Loa Loa (eye worm) glutaminase 0.033 0.0593 0.0739
Trypanosoma brucei unspecified product 0.0088 0.0118 0.1704
Brugia malayi Bromodomain containing protein 0.0035 0.0014 0.0007
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0206 0.0348 0.5269
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0134 0.1943
Giardia lamblia PHD finger protein 15 0.0035 0.0014 0.0216
Trypanosoma brucei metacaspase MCA2 0.0032 0.0008 0.0018
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0046 0.0685
Trichomonas vaginalis DNA helicase recq, putative 0.0079 0.01 0.1671
Echinococcus multilocularis phosphoglycerate kinase 1 0.0206 0.0348 0.1134
Trypanosoma brucei phosphoglycerate kinase 0.0075 0.0093 0.132
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0206 0.0348 0.5873
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0038 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0134 0.1943
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0134 0.202
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0032 0.0008 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0048 0.0622
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0075 0.0093 0.1403
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0014 0.0101
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0072 0.0087 0.1302
Trypanosoma brucei phosphoglycerate kinase, putative 0.0075 0.0093 0.132
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0011 0.0171
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0037 0.1051
Leishmania major phosphoglycerate kinase B, cytosolic 0.0206 0.0348 0.5269
Schistosoma mansoni caspase-7 (C14 family) 0.0032 0.0008 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0008 0.0126
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.0029 0.0073
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0032 0.0008 0.0004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0031 0.0078
Brugia malayi jmjC domain containing protein 0.0043 0.0029 0.0022
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0041 0.0114
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0031 0.0037
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0047 0.0037 0.0098
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0008 0.0126
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0032 0.0008 0.0236
Plasmodium vivax importin-beta 2, putative 0.0035 0.0014 0.0194
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.01 0.0141 0.0446
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0068 0.1018
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.01 0.0141 0.0446
Loa Loa (eye worm) hypothetical protein 0.0047 0.0038 0.0039
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0064 0.0071 0.0088
Entamoeba histolytica phosphoglycerate kinase, putative 0.0206 0.0348 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0284 0.4291
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0029 0.0073
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0171 0.0546
Schistosoma mansoni terminal deoxycytidyl transferase 0.0064 0.0071 0.0088
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0049 0.0042 0.1021
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0029 0.0028
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.005 0.0652
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0046 0.0685
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0075 0.0093 0.1403
Echinococcus granulosus bloom syndrome protein 0.0079 0.01 0.0308
Giardia lamblia Phosphoglycerate kinase 0.0206 0.0348 1
Treponema pallidum phosphoglycerate kinase 0.0206 0.0348 0.5
Mycobacterium ulcerans glutaminase 0.033 0.0593 1
Schistosoma mansoni chromobox protein 0.0084 0.011 0.0138
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.0007 0.0106
Onchocerca volvulus Diphthamide biosynthesis protein 7 homolog 0.1567 0.3018 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0048 0.0622
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0029 0.0035
Schistosoma mansoni blooms syndrome DNA helicase 0.0055 0.0053 0.0066
Schistosoma mansoni apoptosis regulator bax 0.01 0.0141 0.0177
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0045 0.0746
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0072 0.0087 0.2332
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0064 0.0071 0.0081
Schistosoma mansoni hypothetical protein 0.0035 0.0014 0.0017
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0045 0.0746
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0008 0.0126
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0075 0.0093 0.1403
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0047 0.0037 0.0098
Schistosoma mansoni caspase-3 (C14 family) 0.0032 0.0008 0.0009
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.4073 0.7932 1
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0041 0.0114
Brugia malayi Phosphoglycerate kinase 0.0206 0.0348 0.0342
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0008 0.0126
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0037 0.003
Schistosoma mansoni hypothetical protein 0.0372 0.0674 0.0849
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0008 0.0126
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0674 0.0842
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0008 0.0126
Echinococcus granulosus caspase 0.0032 0.0008 0.0004
Trypanosoma brucei metacaspase 0.0032 0.0008 0.0018
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0014 0.0101
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0206 0.0348 1
Giardia lamblia Sgs1 DNA helicase, putative 0.0047 0.0037 0.0867

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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