Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | microtubule associated protein 2 | 0.0758 | 0.8128 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0503 | 0.5211 | 0.638 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0503 | 0.5211 | 0.638 |
Brugia malayi | hypothetical protein | 0.05 | 0.5185 | 0.5119 |
Brugia malayi | Doublecortin family protein | 0.0084 | 0.0442 | 0.031 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0172 | 0.0126 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0084 | 0.0442 | 0.046 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0172 | 0.1439 | 0.5051 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0172 | 0.1439 | 0.1698 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0271 | 0.2573 | 0.5522 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0058 | 0.0151 | 0.0149 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0092 | 0.0538 | 0.1221 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0172 | 0.1439 | 0.6297 |
Echinococcus multilocularis | 0.0172 | 0.1439 | 0.1698 | |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0172 | 0.1439 | 0.6297 |
Plasmodium vivax | serine/threonine kinase-1, putative | 0.0432 | 0.4408 | 1 |
Brugia malayi | hypothetical protein | 0.0084 | 0.0442 | 0.031 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0172 | 0.1439 | 0.6297 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0057 | 0.0136 | 0.0106 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0271 | 0.2573 | 0.3106 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0271 | 0.2573 | 0.3106 |
Schistosoma mansoni | rab6-interacting | 0.0084 | 0.0442 | 0.0508 |
Brugia malayi | hypoxia-induced factor 1 | 0.0462 | 0.4744 | 0.4671 |
Brugia malayi | Protein kinase domain containing protein | 0.0092 | 0.0538 | 0.0408 |
Brugia malayi | Cytochrome P450 family protein | 0.028 | 0.268 | 0.2579 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0133 | 0.0998 | 0.4107 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0172 | 0.1439 | 0.6297 |
Echinococcus granulosus | single minded 2 | 0.011 | 0.0742 | 0.0833 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0271 | 0.2573 | 0.2471 |
Onchocerca volvulus | 0.0107 | 0.07 | 0.9414 | |
Mycobacterium leprae | putative cytochrome p450 | 0.0172 | 0.1439 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0313 | 0.3046 | 0.3693 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0172 | 0.1439 | 0.3264 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0432 | 0.4408 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0084 | 0.0442 | 0.046 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0058 | 0.0151 | 0.0099 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0432 | 0.4408 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0172 | 0.1439 | 0.3264 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0133 | 0.0998 | 0.1151 |
Brugia malayi | Cytochrome P450 family protein | 0.028 | 0.268 | 0.2579 |
Schistosoma mansoni | cytochrome P450 | 0.0172 | 0.1439 | 0.174 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0092 | 0.0538 | 0.1221 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0084 | 0.0442 | 0.046 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0271 | 0.2573 | 0.3106 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0172 | 0.1439 | 0.6297 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0133 | 0.0998 | 0.2265 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0442 | 0.0413 |
Loa Loa (eye worm) | intermediate filament protein | 0.0107 | 0.07 | 0.0672 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0172 | 0.0176 |
Trypanosoma brucei | cytochrome P450, putative | 0.028 | 0.268 | 0.5782 |
Echinococcus granulosus | RUN | 0.0084 | 0.0442 | 0.046 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0073 | 0.0311 | 0.0347 |
Trypanosoma brucei | kinetoplastid kinetochore protein 19 | 0.0432 | 0.4408 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0107 | 0.07 | 0.0828 |
Schistosoma mansoni | rab6-interacting | 0.0084 | 0.0442 | 0.0508 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0172 | 0.1439 | 0.5051 |
Plasmodium falciparum | protein serine/threonine kinase-1 | 0.0432 | 0.4408 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0327 | 0.3214 | 0.3901 |
Brugia malayi | jmjC domain containing protein | 0.0058 | 0.0151 | 0.0015 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0313 | 0.3046 | 0.6911 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0725 | 0.0697 |
Trypanosoma brucei | protein kinase, putative | 0.0313 | 0.3046 | 0.6677 |
Schistosoma mansoni | lipoxygenase | 0.0503 | 0.5211 | 0.6399 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0172 | 0.1439 | 0.299 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0313 | 0.3046 | 0.3693 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0313 | 0.3046 | 0.6911 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0462 | 0.4744 | 0.4728 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0133 | 0.0998 | 0.0875 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0758 | 0.8128 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0432 | 0.4408 | 1 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0172 | 0.1439 | 0.5051 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0237 | 0.2183 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0049 | 0.0019 |
Echinococcus granulosus | hypothetical protein | 0.0425 | 0.4333 | 0.529 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.028 | 0.268 | 0.2657 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0172 | 0.0126 |
Trypanosoma cruzi | cytochrome P450, putative | 0.028 | 0.268 | 0.6079 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0172 | 0.1439 | 0.5051 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0432 | 0.4408 | 0.5406 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0133 | 0.0998 | 0.1151 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0432 | 0.4408 | 1 |
Leishmania major | protein kinase, putative | 0.0432 | 0.4408 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0172 | 0.1439 | 0.6297 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0172 | 0.1439 | 0.5051 |
Brugia malayi | hypothetical protein | 0.0084 | 0.0442 | 0.031 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.028 | 0.268 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0058 | 0.0151 | 0.0015 |
Brugia malayi | bHLH-PAS transcription factor | 0.011 | 0.0742 | 0.0615 |
Echinococcus granulosus | lamin dm0 | 0.0107 | 0.07 | 0.0781 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0058 | 0.0151 | 0.0149 |
Brugia malayi | Protein kinase domain containing protein | 0.0432 | 0.4408 | 0.4331 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0313 | 0.3046 | 0.3693 |
Echinococcus granulosus | dual specificity protein kinase clk2 | 0.0432 | 0.4408 | 0.5383 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0172 | 0.1439 | 0.5051 |
Echinococcus multilocularis | dual specificity protein kinase clk2 | 0.0432 | 0.4408 | 0.5383 |
Entamoeba histolytica | hypothetical protein | 0.0092 | 0.0538 | 0.1005 |
Loa Loa (eye worm) | hypothetical protein | 0.0271 | 0.2573 | 0.2551 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0313 | 0.3046 | 0.6911 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0271 | 0.2573 | 0.3106 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0313 | 0.3046 | 0.2579 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0071 | 0.0041 |
Entamoeba histolytica | protein kinase, putative | 0.0092 | 0.0538 | 0.1005 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0271 | 0.2573 | 1 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0271 | 0.2573 | 0.3141 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.0151 | 0.0121 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0084 | 0.0442 | 0.046 |
Schistosoma mansoni | lamin | 0.0107 | 0.07 | 0.0828 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.0538 | 0.0628 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0313 | 0.3046 | 0.3025 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0271 | 0.2573 | 0.5838 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0172 | 0.1439 | 0.3264 |
Echinococcus multilocularis | transfer RNA-Lys | 0.011 | 0.0742 | 0.0833 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0313 | 0.3046 | 0.6786 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0133 | 0.0998 | 0.3294 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0172 | 0.1439 | 0.5051 |
Brugia malayi | intermediate filament protein | 0.0107 | 0.07 | 0.0572 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0073 | 0.0311 | 0.0706 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0084 | 0.0442 | 0.046 |
Mycobacterium ulcerans | putative regulatory protein | 0.011 | 0.0742 | 0.2272 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0058 | 0.0151 | 0.0099 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0432 | 0.4408 | 0.5406 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0073 | 0.0311 | 0.0298 |
Brugia malayi | cytochrome P450 | 0.0172 | 0.1439 | 0.1321 |
Loa Loa (eye worm) | hypothetical protein | 0.05 | 0.5185 | 0.5171 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0172 | 0.1439 | 0.5051 |
Echinococcus granulosus | lamin | 0.0107 | 0.07 | 0.0781 |
Echinococcus multilocularis | musashi | 0.0107 | 0.07 | 0.0781 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0313 | 0.3046 | 0.6911 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0442 | 0.0413 |
Echinococcus granulosus | dual specificity | 0.0092 | 0.0538 | 0.058 |
Schistosoma mansoni | loxhd1 | 0.0084 | 0.0442 | 0.0508 |
Echinococcus multilocularis | tumor protein p63 | 0.0327 | 0.3214 | 0.3901 |
Schistosoma mansoni | lamin | 0.0107 | 0.07 | 0.0828 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0133 | 0.0998 | 0.1196 |
Onchocerca volvulus | 0.0084 | 0.0442 | 0.5782 | |
Echinococcus multilocularis | dual specificity | 0.0092 | 0.0538 | 0.058 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0084 | 0.0442 | 0.046 |
Loa Loa (eye worm) | cytochrome P450 | 0.0172 | 0.1439 | 0.1413 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0172 | 0.1439 | 0.6297 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0313 | 0.3046 | 0.2579 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0172 | 0.0176 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0313 | 0.3046 | 0.2579 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0172 | 0.1439 | 0.3264 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0172 | 0.1439 | 0.6297 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0172 | 0.1439 | 0.6297 |
Echinococcus multilocularis | lamin dm0 | 0.0107 | 0.07 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.4333 | 0.4316 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0172 | 0.1439 | 0.5051 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0172 | 0.1439 | 0.6297 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0172 | 0.1439 | 0.5051 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0073 | 0.0311 | 0.0282 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0271 | 0.2573 | 0.3106 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0092 | 0.0538 | 0.1221 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0172 | 0.1439 | 0.5051 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0271 | 0.2573 | 0.3141 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0923 | 1 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0172 | 0.1439 | 0.3264 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0313 | 0.3046 | 0.2579 |
Schistosoma mansoni | lipoxygenase | 0.0351 | 0.3488 | 0.427 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0133 | 0.0998 | 0.3294 |
Loa Loa (eye worm) | CYP4Cod1 | 0.028 | 0.268 | 0.2657 |
Giardia lamblia | Kinase, CMGC CLK | 0.0432 | 0.4408 | 1 |
Leishmania major | cytochrome p450-like protein | 0.028 | 0.268 | 0.6079 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0107 | 0.07 | 0.0572 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0678 | 0.065 |
Toxoplasma gondii | cell-cycle-associated protein kinase CLK, putative | 0.0432 | 0.4408 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0172 | 0.1439 | 0.6297 |
Onchocerca volvulus | 0.0107 | 0.07 | 0.9414 | |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0172 | 0.1439 | 0.6297 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0172 | 0.1439 | 0.5051 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0172 | 0.1439 | 0.2753 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0172 | 0.1439 | 0.5051 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0073 | 0.0311 | 0.0178 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0172 | 0.1439 | 0.5051 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0172 | 0.1439 | 0.6297 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0112 | 0.0763 | 0.0735 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0172 | 0.1439 | 0.6297 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0073 | 0.0311 | 0.0706 |
Brugia malayi | PAS domain containing protein | 0.0149 | 0.1184 | 0.1062 |
Echinococcus granulosus | intermediate filament protein | 0.0107 | 0.07 | 0.0781 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0058 | 0.0151 | 0.0099 |
Entamoeba histolytica | protein kinase, putative | 0.0092 | 0.0538 | 0.1005 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0092 | 0.0538 | 0.051 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0172 | 0.1439 | 0.6297 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0758 | 0.8128 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0092 | 0.0538 | 0.1005 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.028 | 0.268 | 0.2657 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0313 | 0.3046 | 0.6911 |
Loa Loa (eye worm) | doublecortin family protein | 0.0084 | 0.0442 | 0.0413 |
Brugia malayi | Cytochrome P450 family protein | 0.0172 | 0.1439 | 0.1321 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0172 | 0.1439 | 0.6297 |
Trypanosoma cruzi | cytochrome P450, putative | 0.028 | 0.268 | 0.6079 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0271 | 0.2573 | 0.5838 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0092 | 0.0538 | 0.0555 |
Schistosoma mansoni | polycystin 1-related | 0.0084 | 0.0442 | 0.0508 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0172 | 0.1439 | 0.6297 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0172 | 0.1439 | 0.6297 |
Brugia malayi | MAP kinase sur-1 | 0.0313 | 0.3046 | 0.2951 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0172 | 0.1439 | 0.6297 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0313 | 0.3046 | 0.6911 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0271 | 0.2573 | 0.3106 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0073 | 0.0311 | 0.0298 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0107 | 0.07 | 0.0672 |
Loa Loa (eye worm) | CMGC/CLK protein kinase | 0.0432 | 0.4408 | 0.4391 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0271 | 0.2573 | 0.5838 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0172 | 0.1439 | 0.5051 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0464 | 0.0435 |
Leishmania major | protein kinase, putative | 0.0432 | 0.4408 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0084 | 0.0442 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0049 | 0.0019 |
Onchocerca volvulus | 0.011 | 0.0742 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.1439 | 0.174 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0172 | 0.1439 | 0.5051 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0172 | 0.1439 | 0.5051 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0172 | 0.1439 | 0.5051 |
Echinococcus multilocularis | RUN | 0.0084 | 0.0442 | 0.046 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0313 | 0.3046 | 0.3693 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0172 | 0.1439 | 0.5051 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0313 | 0.3046 | 0.2579 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0404 | 0.4083 | 0.4065 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0313 | 0.3046 | 0.3725 |
Schistosoma mansoni | jumonji domain containing protein | 0.0058 | 0.0151 | 0.0149 |
Onchocerca volvulus | 0.0084 | 0.0442 | 0.5782 | |
Trypanosoma brucei | kinetoplastid kinetochore protein 10 | 0.0432 | 0.4408 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0172 | 0.1439 | 0.6297 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0172 | 0.1439 | 0.5 |
Echinococcus multilocularis | lamin | 0.0107 | 0.07 | 0.0781 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0172 | 0.1439 | 0.3264 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0073 | 0.0311 | 0.0706 |
Schistosoma mansoni | single-minded | 0.0149 | 0.1184 | 0.1425 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0432 | 0.4408 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.07 | 0.0672 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0313 | 0.3046 | 0.6677 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0172 | 0.0391 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0172 | 0.1439 | 0.5051 |
Echinococcus multilocularis | 0.0425 | 0.4333 | 0.529 | |
Brugia malayi | Cytochrome P450 family protein | 0.0404 | 0.4083 | 0.4002 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0464 | 0.0435 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0058 | 0.0151 | 0.0099 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0149 | 0.1184 | 0.1425 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | = 42.1 uM | Antiproliferative activity against human HL60 cells after 3 days by trypan blue staining | ChEMBL. | 18491866 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.