Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | neuropeptide s receptor | 0.0448 | 0.6672 | 0.6672 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0021 | 0.0021 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0021 | 0.0072 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0054 | 0.0688 | 0.0688 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1491 | 0.331 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0021 | 0.0021 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0136 | 0.1932 | 0.1932 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0021 | 0.0021 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.031 | 0.031 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.0671 | 0.1357 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0107 | 0.1491 | 0.3389 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.4298 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0021 | 0.0072 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0102 | 0.035 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.4298 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.4298 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0102 | 0.035 |
Echinococcus granulosus | snurportin 1 | 0.0305 | 0.4495 | 0.4495 |
Schistosoma mansoni | hypothetical protein | 0.0667 | 1 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0206 | 0.2994 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.1236 | 0.2749 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0095 | 0.131 | 0.2964 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0293 | 0.0293 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0185 | 0.2678 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0054 | 0.0688 | 0.4426 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0116 | 0.1626 | 0.4769 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0294 | 0.0655 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0095 | 0.131 | 0.131 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0104 | 0.1449 | 0.4232 |
Trypanosoma brucei | polo-like protein kinase | 0.0107 | 0.1491 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0407 | 0.2472 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0102 | 0.0102 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0102 | 0.035 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0016 | 0.0102 | 0.035 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0294 | 0.0983 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0143 | 0.2028 | 0.7526 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0012 | 0.0037 | 0.0125 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0104 | 0.1449 | 0.532 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0136 | 0.1932 | 0.1932 |
Onchocerca volvulus | 0.0036 | 0.0407 | 0.1132 | |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0407 | 0.1078 |
Brugia malayi | Flap endonuclease-1 | 0.0027 | 0.0267 | 0.0893 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0344 | 0.115 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0344 | 0.0344 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0292 | 0.4298 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0021 | 0.0021 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0021 | 0.0021 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0102 | 0.0192 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0344 | 0.0344 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0102 | 0.035 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0013 | 0.0051 | 0.0051 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.0688 | 0.1398 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0104 | 0.1449 | 0.4232 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0294 | 0.0926 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.0557 | 0.1531 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0021 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0407 | 0.0905 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.4298 | 1 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0027 | 0.0267 | 0.0595 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0448 | 0.6672 | 0.6672 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0305 | 0.4495 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0021 | 0.0021 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0407 | 0.1078 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0021 | 0.0048 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0407 | 0.1355 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.1236 | 0.1236 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0212 | 0.0264 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0097 | 0.1332 | 0.1332 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0021 | 0.0072 |
Schistosoma mansoni | kinase | 0.0055 | 0.0692 | 0.0692 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0021 | 0.0072 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0212 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.139 | 0.3091 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0021 | 0.0072 |
Schistosoma mansoni | hypothetical protein | 0.0305 | 0.4495 | 0.4495 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0407 | 0.1359 |
Schistosoma mansoni | ran | 0.0021 | 0.018 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0482 | 0.1073 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0016 | 0.0102 | 0.035 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0021 | 0.0021 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0294 | 0.169 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0021 | 0.0021 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0027 | 0.0267 | 0.1503 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0021 | 0.0072 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.018 | 0.0894 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0143 | 0.2028 | 0.7526 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.4298 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0021 | 0.0021 |
Schistosoma mansoni | dihydropteridine reductase | 0.0013 | 0.0051 | 0.0051 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.031 | 0.031 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0107 | 0.1491 | 0.4314 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0185 | 0.2678 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0021 | 0.0048 |
Onchocerca volvulus | 0.0235 | 0.3427 | 1 | |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0407 | 0.1078 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.0557 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.131 | 0.2914 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0344 | 0.0344 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.0688 | 0.1398 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0212 | 0.112 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.046 | 0.046 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1491 | 0.331 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0095 | 0.131 | 0.4376 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0021 | 0.0021 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0102 | 0.035 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0021 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0021 | 0.0048 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0054 | 0.0688 | 0.0688 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0407 | 0.1355 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0013 | 0.0051 | 0.0114 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0407 | 0.1355 |
Schistosoma mansoni | hypothetical protein | 0.0667 | 1 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0407 | 0.1359 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0135 | 0.1911 | 0.4252 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0344 | 0.0344 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.0557 | 0.1238 |
Onchocerca volvulus | 0.0013 | 0.0051 | 0.0087 | |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0101 | 0.139 | 0.4642 |
Onchocerca volvulus | 0.0036 | 0.0407 | 0.1132 | |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0021 | 0.0021 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0102 | 0.0192 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0101 | 0.139 | 0.3091 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.0906 | 0.3025 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0021 | 0.0072 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.018 | 0.0894 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0135 | 0.1911 | 0.4252 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0021 | 0.0021 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0185 | 0.2678 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0051 | 0.0114 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0021 | 0.0021 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0054 | 0.0688 | 0.0688 |
Schistosoma mansoni | flap endonuclease-1 | 0.0024 | 0.0228 | 0.0228 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0407 | 0.0407 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.0557 | 0.1238 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0016 | 0.0102 | 0.0192 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0102 | 0.0192 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0102 | 0.035 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0051 | 0.0171 |
Brugia malayi | glutathione reductase | 0.0046 | 0.0557 | 0.1859 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0185 | 0.2678 | 0.7956 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0407 | 0.0728 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0102 | 0.0102 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0407 | 0.0407 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0622 | 0.1385 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0021 | 0.0021 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0102 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0344 | 0.0766 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0102 | 0.0192 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0185 | 0.2678 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.046 | 0.046 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0407 | 0.0407 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0102 | 0.0192 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.0557 | 0.1924 |
Echinococcus multilocularis | snurportin 1 | 0.0305 | 0.4495 | 0.4495 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0407 | 0.0407 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0016 | 0.0102 | 0.0192 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0107 | 0.1491 | 0.1491 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.0557 | 0.0557 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0021 | 0.0072 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0102 | 0.0339 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0407 | 0.0728 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.0688 | 0.1398 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0021 | 0.0021 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.0557 | 0.3512 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0027 | 0.0267 | 0.0395 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0021 | 0.0021 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.1236 | 0.1236 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0016 | 0.0102 | 0.035 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0116 | 0.1626 | 0.4769 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.031 | 0.031 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0027 | 0.0267 | 0.0267 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0482 | 0.0482 |
Entamoeba histolytica | Flap nuclease, putative | 0.0027 | 0.0267 | 0.0509 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0021 | 0.0021 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0292 | 0.4298 | 1 |
Schistosoma mansoni | ran | 0.0021 | 0.018 | 0.018 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0407 | 0.1078 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.018 | 0.0186 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0292 | 0.4298 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0095 | 0.131 | 0.131 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0021 | 0.0021 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.018 | 0.018 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.046 | 0.046 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0021 | 0.0048 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0906 | 0.0906 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0016 | 0.0102 | 0.0153 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0054 | 0.0688 | 0.0688 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0102 | 0.035 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0016 | 0.0102 | 0.0192 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.1222 | 0.1222 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.1236 | 0.1236 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0054 | 0.0688 | 0.2425 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.018 | 0.04 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0021 | 0.0072 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0143 | 0.2028 | 0.5988 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.018 | 0.049 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0016 | 0.0102 | 0.0192 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0021 | 0.0072 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0212 | 0.038 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1491 | 0.331 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0051 | 0.0171 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0407 | 0.1078 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1491 | 0.331 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.031 | 0.1035 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0482 | 0.0908 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0027 | 0.0267 | 0.1503 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0021 | 0.0048 |
Brugia malayi | MAP kinase sur-1 | 0.0054 | 0.0688 | 0.2299 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.0671 | 0.1357 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0482 | 0.0482 |
Trichomonas vaginalis | hypothetical protein | 0.0185 | 0.2678 | 0.614 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.1491 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.4298 | 1 |
Onchocerca volvulus | 0.0036 | 0.0407 | 0.1132 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0107 | 0.1491 | 0.1491 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0101 | 0.139 | 0.4642 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0104 | 0.1449 | 0.4232 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0407 | 0.1355 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0294 | 0.0926 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0407 | 0.1078 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0407 | 0.1359 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0021 | 0.0048 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0206 | 0.2994 | 0.666 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.0557 | 0.1924 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0482 | 0.1073 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.1236 | 0.1236 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0407 | 0.2472 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.031 | 0.031 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0212 | 0.0264 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0294 | 0.169 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0407 | 0.1078 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0407 | 0.0728 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0116 | 0.1626 | 0.5994 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0021 | 0.0072 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.1236 | 0.1236 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.018 | 0.0894 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0021 | 0.0048 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.018 | 0.0186 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.057 | 0.057 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0021 | 0.0072 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0054 | 0.0688 | 0.1531 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0407 | 0.1355 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0448 | 0.6672 | 0.6672 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0448 | 0.6672 | 0.6672 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.031 | 0.0984 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0021 | 0.0048 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0021 | 0.0021 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0407 | 0.1078 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0407 | 0.0905 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0021 | 0.0048 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.018 | 0.049 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0104 | 0.1449 | 0.4232 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0294 | 0.0294 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0102 | 0.035 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0027 | 0.0267 | 0.1503 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0344 | 0.0344 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.1491 | 1 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0013 | 0.0051 | 0.0114 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0021 | 0.0021 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.4298 | 1 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.018 | 0.0303 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.018 | 0.018 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.0557 | 0.1924 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.046 | 0.046 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0107 | 0.1491 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0054 | 0.0688 | 0.4426 |
Plasmodium falciparum | flap endonuclease 1 | 0.0027 | 0.0267 | 0.0824 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0054 | 0.0688 | 0.4426 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.018 | 0.0894 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0054 | 0.0688 | 0.4426 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0021 | 0.0072 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0407 | 0.1355 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0021 | 0.0021 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0407 | 0.2472 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0021 | 0.0021 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0012 | 0.0037 | 0.0125 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0407 | 0.1355 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0344 | 0.0344 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0016 | 0.0102 | 0.035 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0344 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0407 | 0.0905 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0021 | 0.0021 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0021 | 0.0021 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0344 | 0.115 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0013 | 0.0051 | 0.0051 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0021 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0407 | 0.0905 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0021 | 0.0021 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0344 | 0.0344 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.018 | 0.06 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0407 | 0.0905 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0294 | 0.0294 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.1095 | 0.3657 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0021 | 0.0072 |
Giardia lamblia | Kinase, PLK | 0.0107 | 0.1491 | 0.331 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0054 | 0.0688 | 0.1398 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.031 | 0.031 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0021 | 0.0021 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0102 | 0.0192 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.018 | 0.049 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.023 | 0.3353 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.0557 | 0.3512 |
Onchocerca volvulus | 0.0013 | 0.0051 | 0.0087 | |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0102 | 0.035 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.0688 | 0.1398 |
Brugia malayi | MH2 domain containing protein | 0.0135 | 0.1911 | 0.6384 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1491 | 0.331 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0021 | 0.0072 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0021 | 0.0021 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0107 | 0.1491 | 0.4979 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0294 | 0.0294 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0407 | 0.1355 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.1236 | 0.1236 |
Trichomonas vaginalis | set domain proteins, putative | 0.0235 | 0.3427 | 0.7924 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0407 | 0.2472 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0021 | 0.0072 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0292 | 0.4298 | 1 |
Echinococcus granulosus | flap endonuclease 1 | 0.0027 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0344 | 0.0766 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0102 | 0.035 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0021 | 0.0021 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0054 | 0.0688 | 0.4426 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.0557 | 0.0557 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0407 | 0.1078 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.1222 | 0.1222 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.0557 | 0.1859 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1491 | 0.331 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0021 | 0.0048 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0407 | 0.0728 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0021 | 0.0048 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1491 | 0.331 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0212 | 0.112 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.031 | 0.031 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0185 | 0.2678 | 1 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0294 | 0.0926 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0482 | 0.0482 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0021 | 0.0048 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.031 | 0.031 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0021 | 0.0021 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0482 | 0.0482 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0021 | 0.0072 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0102 | 0.035 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0102 | 0.0192 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.4298 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0102 | 0.0192 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0407 | 0.0728 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0344 | 0.0344 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0407 | 0.0728 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0407 | 0.0905 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.031 | 0.0689 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0407 | 0.1078 |
Trypanosoma brucei | protein kinase, putative | 0.0054 | 0.0688 | 0.4426 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0021 | 0.0048 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0185 | 0.2678 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0102 | 0.035 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.1236 | 0.4127 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0054 | 0.0688 | 0.4426 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0016 | 0.0102 | 0.035 |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0051 | 0.0114 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0344 | 0.0344 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0407 | 0.1359 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0027 | 0.0267 | 0.0395 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0102 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0906 | 0.2015 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0102 | 0.0102 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0021 | 0.0072 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0107 | 0.1491 | 0.3316 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0107 | 0.1491 | 0.1491 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0021 | 0.0048 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0104 | 0.1449 | 0.4232 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0407 | 0.0905 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.0557 | 0.1924 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0407 | 0.1355 |
Mycobacterium tuberculosis | Probable reductase | 0.0104 | 0.1449 | 0.4232 |
Echinococcus multilocularis | geminin | 0.0667 | 1 | 1 |
Leishmania major | trypanothione reductase | 0.0046 | 0.0557 | 0.3512 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0027 | 0.0267 | 0.0824 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0116 | 0.1626 | 0.4769 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0185 | 0.2678 | 1 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0482 | 0.1611 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0054 | 0.0688 | 0.0688 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0482 | 0.0482 |
Onchocerca volvulus | 0.003 | 0.031 | 0.0846 | |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0021 | 0.0048 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0407 | 0.0905 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0013 | 0.0051 | 0.0051 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0054 | 0.0688 | 0.4426 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0027 | 0.0267 | 0.0824 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.1236 | 0.1236 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.031 | 0.0984 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.