Detailed information for compound 991577

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 477.771 | Formula: C22H19Cl3N4O2
  • H donors: 1 H acceptors: 4 LogP: 5.78 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCc1c(nn(c1c1ccc(cc1)Cl)c1ccc(cc1Cl)Cl)c1nnc(o1)C(C)(C)C
  • InChi: 1S/C22H19Cl3N4O2/c1-22(2,3)21-27-26-20(31-21)18-15(11-30)19(12-4-6-13(23)7-5-12)29(28-18)17-9-8-14(24)10-16(17)25/h4-10,30H,11H2,1-3H3
  • InChiKey: DIMKYPXYSFBFGN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cannabinoid receptor 2 (macrophage) Starlite/ChEMBL References
Rattus norvegicus Cannabinoid CB1 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis tubulin gamma chain, putative 0.1347 0.2685 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0166 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Trichomonas vaginalis helicase, putative 0.002 0.0005 0.002
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0064 0.0237
Brugia malayi nuclear hormone receptor 0.0134 0.0236 0.088
Onchocerca volvulus 0.0134 0.0236 0.2654
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.006 0.0221
Schistosoma mansoni nuclear receptor nhr-48 0.0063 0.0093 0.0267
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Schistosoma mansoni tyrosine kinase 0.0166 0.0299 0.0859
Entamoeba histolytica tartrate dehydrogenase, putative 0.002 0.0005 0.0017
Schistosoma mansoni hypothetical protein 0.0075 0.0117 0.0336
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.0341 0.127
Giardia lamblia Epsilon tubulin 0.04 0.0772 0.2868
Toxoplasma gondii LsmAD domain-containing protein 0.0259 0.0488 0.1817
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0009 0.0026
Echinococcus multilocularis chromobox protein 1 0.007 0.0106 0.0106
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.005 0.0066 0.0066
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0109 0.0184 0.0529
Loa Loa (eye worm) hypothetical protein 0.0186 0.0341 0.127
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0067 0.0194
Trichomonas vaginalis tubulin beta chain, putative 0.1007 0.1998 0.7444
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.005 0.0066 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Onchocerca volvulus 0.0058 0.0082 0.0925
Schistosoma mansoni single-minded 0.0051 0.0067 0.0194
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0134 0.0236 0.088
Echinococcus multilocularis Tubulin alpha 1 chain 0.1007 0.1998 0.1998
Loa Loa (eye worm) hypothetical protein 0.0247 0.0463 0.1726
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0193 0.0354 0.1018
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0099 0.0358
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0035 0.0132
Treponema pallidum cell division protein FtsZ 0.0346 0.0664 1
Echinococcus granulosus neuropeptide receptor A26 0.0498 0.097 0.2786
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.015
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0022 0.008
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.041 0.0792 0.2949
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0186 0.0341 0.127
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0045 0.0168
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0045 0.0168
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.002 0.0005 0.0014
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0062 0.0062
Trypanosoma cruzi cruzipain precursor, putative 0.0067 0.0099 0.037
Plasmodium falciparum ataxin-2 like protein, putative 0.0259 0.0488 0.1817
Schistosoma mansoni tubulin subunit beta 0.1347 0.2685 0.7711
Echinococcus multilocularis smad 0.0034 0.0033 0.0033
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0099 0.037
Brugia malayi MH2 domain containing protein 0.0034 0.0033 0.0123
Leishmania major beta tubulin 0.1347 0.2685 1
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0026 0.0016 0.0016
Loa Loa (eye worm) hypoxia-induced factor 1 0.0157 0.0282 0.1051
Echinococcus multilocularis sterol regulatory element binding protein 0.0304 0.0579 0.0579
Leishmania major delta tubulin, putative 0.0684 0.1345 0.501
Mycobacterium tuberculosis Cell division protein FtsZ 0.0346 0.0664 0.2801
Trichomonas vaginalis conserved hypothetical protein 0.0346 0.0664 0.2472
Echinococcus multilocularis tubulin subunit TubB 0.1007 0.1998 0.1998
Leishmania major beta tubulin 0.1347 0.2685 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0134 0.0236 0.0679
Loa Loa (eye worm) hypothetical protein 0.0186 0.0341 0.127
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0055
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0 0.0001
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0043 0.0159
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0106
Onchocerca volvulus Putative organic anion transporter 0.0058 0.0082 0.0925
Leishmania major eukaryotic initiation factor 4a, putative 0.0026 0.0016 0.0061
Loa Loa (eye worm) hypothetical protein 0.0048 0.0062 0.0229
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0027 0.002 0.002
Schistosoma mansoni nuclear receptor 0.0063 0.0093 0.0267
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.0192 0.0812
Trichomonas vaginalis tubulin epsilon chain, putative 0.1007 0.1998 0.7444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0016 0.006
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0026 0.0016 0.0061
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0041 0.0615
Brugia malayi SPARC precursor 0.004 0.0045 0.0168
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0106
Brugia malayi Probable isocitrate dehydrogenase 0.002 0.0005 0.0017
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0049 0.0063 0.0181
Plasmodium falciparum glutathione reductase 0.0049 0.0065 0.024
Echinococcus granulosus tubulin alpha 3 chain 0.1007 0.1998 0.574
Schistosoma mansoni alpha tubulin 0.1007 0.1998 0.574
Brugia malayi protein C24B5.3 0.0043 0.0052 0.0192
Echinococcus granulosus beta tubulin 0.1347 0.2685 0.7711
Echinococcus granulosus Immunoglobulin 0.0022 0.0009 0.0026
Schistosoma mansoni hypothetical protein 0.0049 0.0063 0.0181
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0131 0.023 0.0662
Echinococcus multilocularis tyrosine protein kinase Abl 0.0102 0.0171 0.0171
Echinococcus multilocularis 0.0096 0.016 0.016
Echinococcus multilocularis tubulin alpha 3 chain 0.1007 0.1998 0.1998
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0043 0.0123
Entamoeba histolytica hypothetical protein 0.0075 0.0117 0.0435
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Loa Loa (eye worm) DR-78 0.0063 0.0093 0.0345
Loa Loa (eye worm) nuclear hormone receptor 0.0063 0.0093 0.0345
Leishmania major hypothetical protein, conserved 0.0259 0.0488 0.1817
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0108 0.0403
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0002 0.0008
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0026 0.0016 0.0049
Trichomonas vaginalis tubulin beta chain, putative 0.1007 0.1998 0.7444
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0099 0.0358
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.006 0.0221
Leishmania major hypothetical protein, conserved 0.0186 0.0341 0.127
Loa Loa (eye worm) hypothetical protein 0.0186 0.0341 0.127
Loa Loa (eye worm) MH2 domain-containing protein 0.0497 0.0968 0.3604
Trypanosoma brucei PAB1-binding protein , putative 0.0259 0.0488 0.1808
Onchocerca volvulus 0.0043 0.0052 0.0579
Brugia malayi mbt repeat family protein 0.0048 0.0062 0.0229
Loa Loa (eye worm) hypothetical protein 0.0239 0.0448 0.1666
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0063 0.0093 0.0345
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0043 0.016
Trypanosoma cruzi alpha tubulin, putative 0.1007 0.1998 0.7444
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0512 0.1908
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0022 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0058 0.0082 0.0306
Schistosoma mansoni hypothetical protein 0.0293 0.0557 0.1601
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0063 0.0093 0.0093
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0015 0.0063
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0116 0.02 0.0573
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0016 0.0061
Echinococcus granulosus insulin receptor 0.0104 0.0174 0.0499
Brugia malayi Furin-like cysteine rich region family protein 0.0315 0.0602 0.2241
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0055 0.0205
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0033 0.0095
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0061
Echinococcus granulosus Tubulin alpha 1 chain 0.1007 0.1998 0.574
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0009
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0025 0.0093
Echinococcus granulosus lamin 0.0028 0.0022 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.006 0.0222
Loa Loa (eye worm) patched family protein 0.0043 0.0052 0.0192
Trichomonas vaginalis tubulin epsilon chain, putative 0.1347 0.2685 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0134 0.0236 0.0679
Echinococcus multilocularis peroxisome assembly protein 26 0.1007 0.1998 0.1998
Echinococcus multilocularis tubulin gamma 1 chain 0.081 0.1601 0.1601
Toxoplasma gondii beta tubulin 0.1347 0.2685 1
Echinococcus multilocularis integrin alpha ps 0.0034 0.0034 0.0034
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.0117 0.0117
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0064 0.0237
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0057
Echinococcus granulosus tubulin gamma 1 chain 0.081 0.1601 0.4598
Plasmodium vivax patched family protein, putative 0.0043 0.0052 0.0192
Entamoeba histolytica tubulin gamma chain 0.081 0.1601 0.5962
Trichomonas vaginalis chromobox protein, putative 0.007 0.0106 0.0396
Echinococcus granulosus tubulin delta chain 0.0346 0.0664 0.1906
Leishmania major zeta tubulin, putative 0.091 0.1803 0.6715
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.025 0.0717
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0 0.0001
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.0192 0.0812
Giardia lamblia Beta tubulin 0.1347 0.2685 1
Mycobacterium tuberculosis Conserved protein 0.0186 0.0341 0.144
Loa Loa (eye worm) Smad1 0.0034 0.0033 0.0123
Brugia malayi Tubulin alpha-2 chain 0.1007 0.1998 0.7444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0035 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0046 0.0171
Brugia malayi Nuclear hormone receptor-like 1 0.0134 0.0236 0.088
Onchocerca volvulus Putative organic anion transporter 0.0058 0.0082 0.0925
Echinococcus granulosus tumor protein p63 0.0353 0.0677 0.1945
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.0463 0.0463
Brugia malayi tubulin alpha chain - mouse 0.1007 0.1998 0.7444
Schistosoma mansoni tubulin subunit beta 0.1347 0.2685 0.7711
Brugia malayi hypothetical protein 0.0025 0.0015 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Echinococcus granulosus beta LACTamase domain containing family member 0.0186 0.0341 0.098
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0026 0.0016 0.0069
Brugia malayi ecdysteroid receptor 0.0134 0.0236 0.088
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0063 0.0093 0.1042
Schistosoma mansoni hypothetical protein 0.0839 0.1658 0.4763
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0015 0.0055
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0049 0.0064 0.0237
Plasmodium falciparum tubulin delta chain, putative 0.0346 0.0664 0.2471
Echinococcus multilocularis Tubulin alpha 1 chain 0.1007 0.1998 0.1998
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0134 0.0236 0.088
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0003 0.0012
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0086 0.0247
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0099 0.0358
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.002
Echinococcus granulosus chromobox protein 1 0.007 0.0106 0.0306
Brugia malayi intermediate filament protein 0.0028 0.0022 0.008
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0043 0.0159
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.002 0.0005 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.025 0.0717
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0093 0.0267
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Echinococcus multilocularis nuclear receptor nhr 48 0.0063 0.0093 0.0093
Echinococcus multilocularis epidermal growth factor receptor 0.0315 0.0602 0.0602
Echinococcus multilocularis beta LACTamase domain containing family member 0.0186 0.0341 0.0341
Brugia malayi beta-tubulin, identical 0.1347 0.2685 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0022 0.0082
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0071 0.0108 0.0311
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.0117 0.0336
Loa Loa (eye worm) hypothetical protein 0.0134 0.0236 0.088
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0 0.0001
Trypanosoma brucei beta tubulin 0.1347 0.2685 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0063 0.0093 0.0267
Schistosoma mansoni smad1 5 8 and 0.0034 0.0033 0.0095
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0033 0.0033
Echinococcus granulosus epidermal growth factor receptor 0.0171 0.0311 0.0893
Trichomonas vaginalis tubulin beta chain, putative 0.1347 0.2685 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0031 0.0114
Brugia malayi prostaglandin transporter 0.0058 0.0082 0.0306
Onchocerca volvulus 0.041 0.0792 0.8896
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Loa Loa (eye worm) TK/INSR protein kinase 0.0104 0.0174 0.0647
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.006 0.0221
Onchocerca volvulus 0.0048 0.0062 0.0692
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0086 0.1294
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.0341 0.127
Entamoeba histolytica tubulin family protein 0.1347 0.2685 1
Brugia malayi hypothetical protein 0.0063 0.0093 0.0345
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0 0.0001
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0186 0.0341 0.144
Loa Loa (eye worm) hypothetical protein 0.0134 0.0236 0.088
Loa Loa (eye worm) hypothetical protein 0.0134 0.0236 0.088
Trypanosoma brucei zeta tubulin 0.091 0.1803 0.6711
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0107 0.018 0.018
Brugia malayi orphan nuclear receptor NR2E1 0.0063 0.0093 0.0345
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0099 0.0358
Echinococcus multilocularis tyrosine protein kinase Fyn 0.005 0.0066 0.0066
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.0108 0.0311
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0 0.0001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.006 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.002
Loa Loa (eye worm) alpha-tubulin 0.1007 0.1998 0.7444
Schistosoma mansoni agrin 0.004 0.0045 0.013
Echinococcus multilocularis integrin beta 2 0.0242 0.0454 0.0454
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0186 0.0341 0.5141
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0134 0.0236 0.2654
Leishmania major beta tubulin 0.1347 0.2685 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0134 0.0236 0.088
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0134 0.0236 0.088
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0134 0.0236 0.088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0035 0.0132
Leishmania major beta tubulin 0.1347 0.2685 1
Brugia malayi Kelch motif family protein 0.005 0.0065 0.0242
Brugia malayi Calcitonin receptor-like protein seb-1 0.0153 0.0275 0.1022
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0063 0.0234
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0134 0.0236 0.088
Loa Loa (eye worm) TK/EGFR protein kinase 0.0315 0.0602 0.2241
Echinococcus granulosus tyrosine protein kinase Fyn 0.005 0.0066 0.019
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.002 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.0071 0.0108 0.0403
Echinococcus multilocularis tyrosine protein kinase Blk 0.0043 0.0052 0.0052
Brugia malayi nuclear receptor RXR 0.0063 0.0093 0.0345
Leishmania major beta tubulin 0.1347 0.2685 1
Mycobacterium tuberculosis Probable hydrolase 0.0186 0.0341 0.144
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.0192 0.2898
Echinococcus granulosus tubulin alpha chain 0.1007 0.1998 0.574
Echinococcus granulosus smad 0.0034 0.0033 0.0095
Trypanosoma cruzi MFS transporter, putative 0.0058 0.0082 0.0306
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Loa Loa (eye worm) BEN-1 protein 0.1347 0.2685 1
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0062 0.0177
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0134 0.0236 0.088
Loa Loa (eye worm) glutaminase 2 0.0275 0.0519 0.1933
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0162 0.0293 0.0293
Toxoplasma gondii thioredoxin reductase 0.0049 0.0065 0.024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0 0.0001
Brugia malayi hypothetical protein 0.0058 0.0082 0.0306
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.003 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0153 0.0275 0.1022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0134 0.0236 0.0679
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0512 0.1908
Loa Loa (eye worm) patched family protein 0.0043 0.0052 0.0192
Echinococcus granulosus peroxisome assembly protein 26 0.1007 0.1998 0.574
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0022 0.0009 0.0026
Trypanosoma brucei epsilon tubulin 0.081 0.1599 0.5952
Loa Loa (eye worm) BEN-1 protein 0.1347 0.2685 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0186 0.0341 0.098
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0162 0.0293 0.0293
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.0272 0.0782
Loa Loa (eye worm) hypothetical protein 0.0031 0.0027 0.01
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Echinococcus granulosus tubulin alpha chain 0.1007 0.1998 0.574
Leishmania major cathepsin L-like protease 0.0067 0.0099 0.037
Loa Loa (eye worm) hypothetical protein 0.0105 0.0177 0.0657
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0055
Schistosoma mansoni tyrosine kinase 0.0221 0.0411 0.1182
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0045 0.0168
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0058 0.0082 0.0082
Brugia malayi Tubulin beta-1 chain 0.1347 0.2685 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0015 0.0055
Toxoplasma gondii patched family protein 0.0043 0.0052 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0016 0.006
Echinococcus multilocularis tubulin delta chain 0.0346 0.0664 0.0664
Mycobacterium ulcerans cell division protein FtsZ 0.0346 0.0664 1
Plasmodium vivax tubulin alpha chain, putative 0.1007 0.1998 0.7444
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0015 0.0055
Onchocerca volvulus 0.0458 0.089 1
Echinococcus granulosus Tubulin alpha 1 chain 0.1007 0.1998 0.574
Toxoplasma gondii beta-tubulin, putative 0.1347 0.2685 1
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0058 0.0082 0.0237
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0043 0.0123
Mycobacterium leprae cell division protein FtsZ 0.0346 0.0664 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0022 0.0009 0.0026
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.0041 0.0041
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0162 0.0293 0.109
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Brugia malayi hypothetical protein 0.0071 0.0108 0.0403
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.0272 0.1013
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0003 0.005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Loa Loa (eye worm) hypothetical protein 0.0058 0.0082 0.0306
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0035 0.0132
Loa Loa (eye worm) tubulin alpha-3 chain 0.0598 0.1172 0.4364
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0044 0.0165
Mycobacterium tuberculosis Conserved protein 0.0186 0.0341 0.144
Echinococcus multilocularis thyroid hormone receptor alpha 0.0266 0.0502 0.0502
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0002 0.0008
Schistosoma mansoni cpg binding protein 0.0088 0.0143 0.0411
Loa Loa (eye worm) CXXC zinc finger family protein 0.0088 0.0143 0.0532
Trichomonas vaginalis tubulin gamma chain, putative 0.081 0.1601 0.5963
Onchocerca volvulus 0.0186 0.0341 0.3833
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0027 0.01
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0061 0.0088 0.0326
Echinococcus granulosus tm gpcr rhodopsin 0.0558 0.1091 0.3134
Loa Loa (eye worm) hypothetical protein 0.0028 0.0021 0.0076
Brugia malayi Patched related family protein 12 0.0043 0.0052 0.0192
Schistosoma mansoni tyrosine kinase 0.0166 0.0299 0.0859
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0075 0.0216
Echinococcus multilocularis dnaJ subfamily B 0.0839 0.1658 0.1658
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0017
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0003 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0134 0.0236 0.088
Echinococcus multilocularis tubulin beta 1 chain 0.1347 0.2685 0.2685
Echinococcus granulosus sterol regulatory element binding protein 0.0304 0.0579 0.1664
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0162 0.0293 0.0841
Echinococcus granulosus tubulin alpha 1C chain 0.1007 0.1998 0.574
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0106
Trypanosoma brucei alpha tubulin 0.1007 0.1998 0.7441
Brugia malayi hypothetical protein 0.0058 0.0082 0.0306
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0162 0.0293 0.1236
Loa Loa (eye worm) integrin beta-2 0.0327 0.0625 0.2328
Brugia malayi Myosin head containing protein 0.0043 0.0052 0.0192
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Loa Loa (eye worm) tubulin alpha 2 0.0661 0.13 0.4841
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0055 0.0159
Schistosoma mansoni cpg binding protein 0.0093 0.0153 0.044
Trypanosoma cruzi tubulin delta chain 0.0684 0.1345 0.501
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0109 0.0184 0.0184
Brugia malayi alpha-tubulin 0.1007 0.1998 0.7444
Brugia malayi nuclear receptor RXR 0.0071 0.0108 0.0403
Echinococcus granulosus tubulin epsilon chain 0.081 0.1599 0.4593
Echinococcus granulosus epidermal growth factor receptor 0.0315 0.0602 0.1728
Schistosoma mansoni hypothetical protein 0.0034 0.0034 0.0098
Loa Loa (eye worm) hypothetical protein 0.0304 0.0579 0.2158
Brugia malayi Nuclear hormone receptor E75 0.0063 0.0093 0.0345
Trypanosoma brucei beta tubulin 0.0756 0.149 0.5546
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0 0.0001
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0104 0.0387
Echinococcus granulosus c src tyrosine kinase 0.002 0.0005 0.0013
Echinococcus granulosus integrin alpha 3 0.0122 0.0212 0.0609
Leishmania major beta tubulin 0.1347 0.2685 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0075 0.0075
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0174 0.0316 0.0909
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0078 0.0289
Echinococcus granulosus tyrosine protein kinase Src42A 0.005 0.0066 0.019
Mycobacterium leprae conserved hypothetical protein 0.0049 0.0064 0.0961
Echinococcus granulosus fibroblast growth factor receptor 4 0.0109 0.0184 0.0529
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.002 0.0005 0.0017
Schistosoma mansoni hypothetical protein 0.0293 0.0557 0.1601
Onchocerca volvulus 0.0174 0.0316 0.3555
Echinococcus multilocularis beta tubulin 0.1347 0.2685 0.2685
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Echinococcus multilocularis musashi 0.0028 0.0022 0.0022
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0756 0.149 0.5551
Echinococcus multilocularis tyrosine protein kinase Src64B 0.005 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0134 0.0236 0.088
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0052 0.0052
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0063 0.0093 0.0267
Echinococcus granulosus alpha tubulin 0.1007 0.1998 0.574
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0512 0.1908
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0324 0.1207
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0033 0.0123
Echinococcus granulosus neuropeptide s receptor 0.0498 0.097 0.2786
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0048 0.0166
Loa Loa (eye worm) hypothetical protein 0.0134 0.0236 0.088
Onchocerca volvulus 0.0063 0.0093 0.1042
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0186 0.0341 0.144
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0121 0.0209 0.0777
Onchocerca volvulus 0.0058 0.0082 0.0925
Echinococcus granulosus isocitrate dehydrogenase NAD 0.002 0.0005 0.0014
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1191 0.2369 1
Schistosoma mansoni Smad4 0.0034 0.0033 0.0095
Toxoplasma gondii ABC1 family protein 0.0186 0.0341 0.127
Loa Loa (eye worm) TK protein kinase 0.0043 0.0052 0.0194
Schistosoma mansoni hypothetical protein 0.0105 0.0177 0.0507
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0026 0.0016 0.0061
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0049 0.0064 0.0237
Schistosoma mansoni hypothetical protein 0.1742 0.3482 1
Schistosoma mansoni tyrosine kinase 0.0166 0.0299 0.0859
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0063 0.0093 0.1042
Entamoeba histolytica hypothetical protein 0.0075 0.0117 0.0435
Schistosoma mansoni blooms syndrome DNA helicase 0.0028 0.0021 0.006
Echinococcus multilocularis ecdysone induced protein 78C 0.0134 0.0236 0.0236
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0134 0.0236 0.0679
Entamoeba histolytica protein kinase, putative 0.0036 0.0038 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0022 0.008
Loa Loa (eye worm) hypothetical protein 0.0055 0.0075 0.0279
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Echinococcus granulosus integrin beta 2 0.0242 0.0454 0.1304
Echinococcus granulosus tubulin alpha chain 0.1007 0.1998 0.574
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.006 0.021
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.0192 0.0812
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0022 0.0009 0.0009
Brugia malayi photoreceptor-specific nuclear receptor 0.0134 0.0236 0.088
Brugia malayi PAS domain containing protein 0.0051 0.0067 0.0251
Brugia malayi Smad1 0.0034 0.0033 0.0123
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0026 0.0016 0.0061
Echinococcus multilocularis tyrosine protein kinase HCK 0.0036 0.0038 0.0038
Schistosoma mansoni tubulin subunit beta 0.1347 0.2685 0.7711
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0558 0.1091 0.1091
Loa Loa (eye worm) hypothetical protein 0.0125 0.0218 0.0811
Loa Loa (eye worm) patched family protein 0.0043 0.0052 0.0192
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.0177 0.0657
Loa Loa (eye worm) hypothetical protein 0.0709 0.1397 0.5203
Schistosoma mansoni hypothetical protein 0.0049 0.0063 0.0181
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0099 0.037
Echinococcus granulosus Solute carrier organic anion transporter family 0.0058 0.0082 0.0237
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Brugia malayi glutaminase DH11.1 0.0275 0.0519 0.1933
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.004 0.0138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0134 0.0236 0.088
Echinococcus multilocularis Tubulin beta 2C chain 0.1347 0.2685 0.2685
Schistosoma mansoni retinoic acid receptor RXR 0.0237 0.0444 0.1276
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.0041 0.0117
Echinococcus multilocularis hypothetical protein 0.1007 0.1998 0.1998
Brugia malayi Tubulin alpha-2 chain 0.1007 0.1998 0.7444
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0041 0.0041
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Brugia malayi hypothetical protein 0.0167 0.0303 0.1127
Leishmania major trypanothione reductase 0.0049 0.0065 0.024
Echinococcus granulosus FTZ F1 alpha 0.0134 0.0236 0.0679
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0099 0.037
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0086 0.1294
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0045 0.0168
Trypanosoma cruzi zeta tubulin, putative 0.091 0.1803 0.6715
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.002 0.0005 0.0017
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0104 0.0376
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Echinococcus granulosus beta tubulin 0.1347 0.2685 0.7711
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0324 0.1207
Loa Loa (eye worm) tubulin alpha chain 0.1007 0.1998 0.7444
Echinococcus multilocularis isocitrate dehydrogenase 0.0162 0.0293 0.0293
Brugia malayi Probable isocitrate dehydrogenase 0.002 0.0005 0.0017
Echinococcus granulosus tyrosine protein kinase Blk 0.0043 0.0052 0.015
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0086 0.0319
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0046 0.0171
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0062 0.0177
Toxoplasma gondii isocitrate dehydrogenase 0.0162 0.0293 0.109
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0055
Schistosoma mansoni niemann-pick C1 (NPC1) 0.072 0.1419 0.4076
Leishmania major beta tubulin 0.1347 0.2685 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0028 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.015
Plasmodium vivax delta tubulin, putative 0.0346 0.0664 0.2471
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.0192 0.0812
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0099 0.0358
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.04 0.0772 0.2876
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0324 0.1207
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.001 0.0024
Echinococcus multilocularis chromobox protein 1 0.007 0.0106 0.0106
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0237
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0271 0.0512 0.1908
Toxoplasma gondii transporter, major facilitator family protein 0.0058 0.0082 0.0306
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0187 0.0343 0.0985
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0065 0.0273
Loa Loa (eye worm) hypothetical protein 0.0458 0.089 0.3314
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0062 0.0177
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0026 0.0016 0.0047
Echinococcus multilocularis tubulin alpha 1C chain 0.1007 0.1998 0.1998
Giardia lamblia GTOR 0.0047 0.006 0.021
Loa Loa (eye worm) hypothetical protein 0.0071 0.0108 0.0403
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0025 0.0093
Echinococcus multilocularis bloom syndrome protein 0.0043 0.0052 0.0052
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0134 0.0236 0.0679
Plasmodium vivax ataxin-2 like protein, putative 0.0259 0.0488 0.1817
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Schistosoma mansoni tyrosine kinase 0.0315 0.0602 0.1728
Brugia malayi eukaryotic initiation factor 4A 0.0026 0.0016 0.0061
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1347 0.2685 0.2685
Loa Loa (eye worm) hypothetical protein 0.0186 0.0341 0.127
Brugia malayi ecdysone receptor 0.0063 0.0093 0.0345
Plasmodium vivax RNA helicase-1, putative 0.0026 0.0016 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.015
Brugia malayi Tyrosine-protein kinase abl-1 0.0102 0.0171 0.0636
Brugia malayi Tubulin alpha chain 0.0346 0.0664 0.2471
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0134 0.0236 0.088
Onchocerca volvulus 0.0043 0.0052 0.0579
Toxoplasma gondii exonuclease III APE 0.0019 0.0003 0.0012
Trypanosoma cruzi PAB1-binding protein , putative 0.0259 0.0488 0.1817
Echinococcus granulosus ATP dependent DNA helicase Q5 0.003 0.0025 0.0073
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0071 0.0108 0.0403
Loa Loa (eye worm) tubulin alpha 2 0.0252 0.0473 0.1761
Loa Loa (eye worm) hypothetical protein 0.0039 0.0044 0.0164
Brugia malayi beta-lactamase family protein 0.0186 0.0341 0.127
Brugia malayi hypothetical protein 0.0458 0.089 0.3314
Loa Loa (eye worm) hypothetical protein 0.0071 0.0108 0.0403
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0512 0.1908
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0684 0.1345 0.501
Loa Loa (eye worm) hypothetical protein 0.0052 0.0069 0.0257
Schistosoma mansoni tyrosine kinase 0.0171 0.0311 0.0893
Loa Loa (eye worm) SRC-1 0.005 0.0066 0.0246
Echinococcus granulosus tubulin subunit beta 0.1347 0.2685 0.7711
Loa Loa (eye worm) tubulin beta-4 chain 0.1347 0.2685 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Schistosoma mansoni tubulin subunit delta 0.0346 0.0664 0.1906
Entamoeba histolytica recQ family helicase, putative 0.0033 0.0031 0.0114
Brugia malayi hypothetical protein 0.0043 0.0052 0.0192
Brugia malayi Tubulin beta chain 0.0346 0.0664 0.2471
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0049 0.0064 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0082 0.0306
Trypanosoma brucei alpha tubulin 0.1007 0.1998 0.7441
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0134 0.0236 0.0236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.0218 0.0919
Brugia malayi Tubulin gamma chain 0.081 0.1601 0.5962
Trypanosoma brucei tubulin delta chain 0.0684 0.1345 0.5004
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0015 0.0224
Brugia malayi hypothetical protein 0.0075 0.0117 0.0435
Onchocerca volvulus 0.005 0.0067 0.0746
Mycobacterium ulcerans beta-lactamase 0.0186 0.0341 0.5141
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0191 0.0709
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.006 0.0221
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0063 0.0063
Echinococcus granulosus chromobox protein 1 0.007 0.0106 0.0306
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.025 0.0717
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.004 0.015
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Onchocerca volvulus 0.0031 0.0027 0.0302
Brugia malayi F/Y-rich N-terminus family protein 0.0027 0.0019 0.0071
Echinococcus granulosus tubulin subunit TubB 0.1007 0.1998 0.574
Schistosoma mansoni DNA helicase recq1 0.003 0.0025 0.0073
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Echinococcus granulosus Nuclear hormone receptor HR96 0.0063 0.0093 0.0267
Schistosoma mansoni zinc finger protein 0.0063 0.0093 0.0267
Loa Loa (eye worm) TK/ABL protein kinase 0.0228 0.0426 0.1585
Onchocerca volvulus 0.0043 0.0052 0.0579
Loa Loa (eye worm) tubulin beta chain 0.0346 0.0664 0.2471
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0022 0.008
Schistosoma mansoni chromobox protein 0.007 0.0106 0.0306
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0104 0.0387
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1007 0.1998 0.7444
Leishmania major beta tubulin 0.1347 0.2685 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.025 0.093
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.004 0.015
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.0341 0.1271
Schistosoma mansoni patched 1 0.0304 0.0579 0.1664
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Echinococcus granulosus Tubulin beta 2C chain 0.1347 0.2685 0.7711
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0003 0.0012
Brugia malayi Fibronectin type III domain containing protein 0.0025 0.0015 0.0055
Echinococcus granulosus Niemann Pick C1 protein 0.0709 0.1397 0.4012
Plasmodium falciparum eukaryotic initiation factor 4A 0.0026 0.0016 0.0061
Brugia malayi Heterochromatin protein 1 0.007 0.0106 0.0396
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0043 0.016
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0015 0.0224
Schistosoma mansoni chromobox protein 0.007 0.0106 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0346 0.0664 0.2472
Trichomonas vaginalis tubulin alpha chain, putative 0.041 0.0792 0.2949
Echinococcus multilocularis agrin 0.004 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Trypanosoma cruzi PAB1-binding protein , putative 0.0259 0.0488 0.1817
Onchocerca volvulus Putative organic anion transporter 0.0058 0.0082 0.0925
Schistosoma mansoni tyrosine kinase 0.0104 0.0174 0.0499
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0324 0.1207
Trichomonas vaginalis tubulin alpha chain, putative 0.041 0.0792 0.2949
Schistosoma mansoni hypothetical protein 0.0116 0.02 0.0573
Trichomonas vaginalis tubulin alpha chain, putative 0.0756 0.149 0.5552
Schistosoma mansoni hypothetical protein 0.1742 0.3482 1
Echinococcus multilocularis protein patched 0.0304 0.0579 0.0579
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0063 0.0093 0.0093
Trichomonas vaginalis tubulin beta chain, putative 0.1007 0.1998 0.7444
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0063 0.0093 0.0093
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0271 0.0512 0.1908
Echinococcus granulosus tyrosine protein kinase ABL1 0.0228 0.0426 0.1223
Echinococcus granulosus GPCR family 2 0.0049 0.0063 0.0181
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.006 0.0222
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0104 0.0387
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0055
Schistosoma mansoni hypothetical protein 0.0293 0.0557 0.1601
Echinococcus granulosus tubulin alpha chain 0.1007 0.1998 0.574
Trichomonas vaginalis chromobox protein, putative 0.007 0.0106 0.0396
Toxoplasma gondii alpha tubulin TUBA1 0.1007 0.1998 0.7444
Mycobacterium ulcerans hypothetical protein 0.0186 0.0341 0.5141
Echinococcus multilocularis Tubulin beta 2C chain 0.1347 0.2685 0.2685
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0003 0.005
Giardia lamblia Alpha-tubulin 0.1007 0.1998 0.7441
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0099 0.0358
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0015 0.0224
Toxoplasma gondii protease inhibitor PI2 0.004 0.0045 0.0168
Onchocerca volvulus Protein patched homolog 0.0043 0.0052 0.0579
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0162 0.0293 0.0293
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.025 0.025
Plasmodium vivax tubulin beta chain, putative 0.1347 0.2685 1
Brugia malayi MH2 domain containing protein 0.0034 0.0033 0.0123
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0043 0.0159
Leishmania major cathepsin L-like protease 0.0067 0.0099 0.037
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.0218 0.328
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0134 0.0236 0.088
Brugia malayi nuclear receptor NHR-88 0.0134 0.0236 0.088
Leishmania major beta tubulin 0.1347 0.2685 1
Leishmania major epsilon tubulin, putative 0.081 0.1599 0.5956
Schistosoma mansoni nephrin 0.0028 0.0021 0.0061
Schistosoma mansoni nuclear hormone receptor 0.0134 0.0236 0.0679
Echinococcus granulosus dnaJ subfamily B 0.0839 0.1658 0.4763
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0134 0.0236 0.088
Trypanosoma cruzi zeta tubulin, putative 0.091 0.1803 0.6715
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0055
Echinococcus granulosus single minded 2 0.0038 0.0041 0.0117
Echinococcus granulosus Protein patched homolog 1 0.0304 0.0579 0.1664
Leishmania major gamma-tubulin 0.081 0.1601 0.5962
Loa Loa (eye worm) RecQ helicase 0.0043 0.0052 0.0192
Loa Loa (eye worm) hypothetical protein 0.0028 0.0022 0.008
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0009 0.0009
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0065 0.0065
Loa Loa (eye worm) tubulin beta-2A chain 0.1347 0.2685 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Echinococcus granulosus tubulin alpha chain 0.1007 0.1998 0.574
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.0117 0.0336
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0661 0.13 0.4841
Schistosoma mansoni tyrosine kinase 0.0171 0.0311 0.0893
Echinococcus multilocularis tubulin alpha chain 0.1007 0.1998 0.1998
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0162 0.0293 0.109
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.0052 0.0192
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Entamoeba histolytica tubulin family protein 0.1347 0.2685 1
Echinococcus multilocularis Tubulin beta 2C chain 0.1347 0.2685 0.2685
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0242
Trypanosoma brucei beta tubulin 0.1347 0.2685 1
Mycobacterium leprae PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) 0.002 0.0005 0.0071
Giardia lamblia Gamma tubulin 0.081 0.1601 0.5958
Trypanosoma brucei epsilon tubulin 0.081 0.1599 0.5952
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0008
Leishmania major beta tubulin 0.1347 0.2685 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0086 0.0362
Brugia malayi glutathione reductase 0.0049 0.0065 0.024
Echinococcus multilocularis tyrosine protein kinase Fgr 0.005 0.0066 0.0066
Toxoplasma gondii patched family protein 0.0043 0.0052 0.0192
Leishmania major beta tubulin 0.1347 0.2685 1
Brugia malayi hypoxia-induced factor 1 0.0157 0.0282 0.1051
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0086 0.0319
Echinococcus multilocularis tubulin alpha chain 0.1007 0.1998 0.1998
Echinococcus multilocularis Tubulin beta 2C chain 0.1347 0.2685 0.2685
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0031 0.0027 0.01
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0134 0.0236 0.088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Echinococcus multilocularis tubulin alpha chain 0.1007 0.1998 0.1998
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Toxoplasma gondii hypothetical protein 0.0043 0.0052 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0035 0.0132
Loa Loa (eye worm) hypothetical protein 0.0134 0.0236 0.088
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0043 0.0123
Schistosoma mansoni follistatin 0.004 0.0045 0.013
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0043 0.0148
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.006 0.0221
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.006 0.0221
Leishmania major isocitrate dehydrogenase, putative 0.002 0.0005 0.0017
Loa Loa (eye worm) agrin synaptic family protein 0.004 0.0045 0.0168
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0162 0.0293 0.109
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Brugia malayi tubulin alpha-2 chain 0.1007 0.1998 0.7444
Echinococcus granulosus tyrosine protein kinase HCK 0.0036 0.0038 0.0109
Trichomonas vaginalis tubulin epsilon chain, putative 0.1007 0.1998 0.7444
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0512 0.1908
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0035 0.0132
Trypanosoma cruzi epsilon tubulin, putative 0.081 0.1599 0.5956
Brugia malayi hypothetical protein 0.017 0.0309 0.115
Schistosoma mansoni thyroid hormone receptor 0.0266 0.0502 0.1441
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.025 0.025
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0003 0.0003
Echinococcus multilocularis tubulin alpha 3 chain 0.1007 0.1998 0.1998
Echinococcus multilocularis lamin dm0 0.0028 0.0022 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0099 0.0358
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0003 0.005
Onchocerca volvulus Protein ultraspiracle homolog 0.0134 0.0236 0.2654
Trypanosoma brucei beta tubulin 0.1347 0.2685 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0065 0.0186
Echinococcus granulosus follistatin 0.004 0.0045 0.013
Loa Loa (eye worm) nuclear factor I 0.0019 0.0003 0.0009
Echinococcus granulosus Tubulin beta 2C chain 0.1347 0.2685 0.7711
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0063 0.0063
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0346 0.0664 0.2472
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0045 0.0168
Echinococcus granulosus twitchin 0.0025 0.0015 0.0044
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0026 0.0016 0.0061
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.006 0.0171
Brugia malayi hypothetical protein 0.0043 0.0052 0.0192
Echinococcus granulosus Tubulin beta 2C chain 0.1347 0.2685 0.7711
Loa Loa (eye worm) hypothetical protein 0.0598 0.1172 0.4364
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0064 0.0226
Echinococcus multilocularis Tubulin beta 2C chain 0.1347 0.2685 0.2685
Loa Loa (eye worm) hypothetical protein 0.0058 0.0082 0.0306
Echinococcus granulosus cpg binding protein 0.0093 0.0153 0.044
Schistosoma mansoni glutaminase 0.0275 0.0519 0.1491
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0033
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0015 0.0224
Brugia malayi hypothetical protein 0.0063 0.0093 0.0345
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.025 0.0717
Schistosoma mansoni ap endonuclease 0.0019 0.0003 0.0009
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0045 0.0168
Echinococcus granulosus transcription factor Dp 1 0.004 0.0045 0.0131
Giardia lamblia Alpha-tubulin 0.1007 0.1998 0.7441
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0043 0.0043
Echinococcus multilocularis epidermal growth factor receptor 0.0171 0.0311 0.0311
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0002 0.0034
Brugia malayi Tubulin alpha chain 0.1007 0.1998 0.7444
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0035 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0134 0.0236 0.088
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0109 0.0184 0.0184
Echinococcus granulosus integrin alpha ps 0.0072 0.0109 0.0314
Loa Loa (eye worm) hypothetical protein 0.0049 0.0063 0.0234
Echinococcus granulosus tyrosine protein kinase Lyn 0.005 0.0066 0.019
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0026 0.0017 0.0061
Loa Loa (eye worm) integrin alpha pat-2 0.0246 0.0462 0.172
Brugia malayi MH2 domain containing protein 0.0497 0.0968 0.3604
Schistosoma mansoni ap endonuclease 0.0019 0.0003 0.0009
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0237 0.0444 0.1276
Mycobacterium ulcerans glutaminase 0.0275 0.0519 0.7822
Brugia malayi mbt repeat family protein 0.0048 0.0062 0.0229
Onchocerca volvulus 0.0058 0.0082 0.0925
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0 0.0001
Brugia malayi Tubulin beta chain 0.041 0.0792 0.2948
Plasmodium vivax glutathione reductase, putative 0.0049 0.0065 0.024
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0048 0.0177
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0033 0.0123
Schistosoma mansoni tubulin subunit epsilon 0.081 0.1599 0.4593
Brugia malayi Steroid receptor seven-up type 2 0.0134 0.0236 0.088
Echinococcus multilocularis tubulin alpha 0.0756 0.149 0.149
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0174 0.0316 0.1178
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0049 0.0064 0.0269
Schistosoma mansoni tyrosine kinase 0.0104 0.0174 0.0499
Brugia malayi protein-tyrosine kinase 0.0043 0.0052 0.0194
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0063 0.0181
Echinococcus granulosus intermediate filament protein 0.0028 0.0022 0.0062
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0004 0.0004
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0026 0.0016 0.0047
Trichomonas vaginalis tubulin, putative 0.1347 0.2685 1
Loa Loa (eye worm) hypothetical protein 0.0661 0.13 0.4841
Schistosoma mansoni tyrosine kinase 0.002 0.0005 0.0013
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0031 0.0102
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Plasmodium vivax hypothetical protein, conserved 0.0186 0.0341 0.127
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.025 0.093
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0069 0.0199
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0075 0.0075
Echinococcus multilocularis Immunoglobulin 0.0022 0.0009 0.0009
Echinococcus multilocularis neuropeptide receptor A26 0.0498 0.097 0.097
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.002 0.0005 0.0018
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0026 0.0016 0.0016
Toxoplasma gondii histone lysine methyltransferase SET1 0.0171 0.031 0.1154
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0003 0.0012
Entamoeba histolytica hypothetical protein 0.0075 0.0117 0.0435
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0 0.0001
Echinococcus multilocularis neuropeptide s receptor 0.0498 0.097 0.097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0016 0.006
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0022 0.0009 0.0026
Giardia lamblia Delta tubulin 0.0346 0.0664 0.2463
Schistosoma mansoni tyrosine kinase 0.002 0.0005 0.0013
Brugia malayi sodium-independent organic anion transporter family protein 0.0058 0.0082 0.0306
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0003 0.0012
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0043 0.0043
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0043 0.0052 0.015
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0168
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0043 0.0159
Echinococcus multilocularis roundabout 2 0.0031 0.0028 0.0028
Entamoeba histolytica tubulin alpha chain, putative 0.1007 0.1998 0.7444
Toxoplasma gondii isocitrate dehydrogenase 0.0162 0.0293 0.109
Trichomonas vaginalis chromobox protein, putative 0.0042 0.005 0.0187
Onchocerca volvulus 0.0025 0.0015 0.0165
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0049 0.0064 0.0961
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0127
Echinococcus multilocularis insulin receptor 0.0104 0.0174 0.0174
Brugia malayi hypothetical protein 0.005 0.0065 0.0242
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0062 0.0692
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0304 0.0579 0.2158
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0104 0.0387
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0062 0.0177
Loa Loa (eye worm) transcription factor SMAD2 0.0497 0.0968 0.3604
Wolbachia endosymbiont of Brugia malayi isocitrate dehydrogenase 0.002 0.0005 0.0071
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0104 0.0387
Trichomonas vaginalis tubulin alpha chain, putative 0.1347 0.2685 1
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.003 0.0025 0.0093
Brugia malayi beta-lactamase 0.0186 0.0341 0.127
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0015 0.0057
Echinococcus multilocularis integrin alpha ps 0.0072 0.0109 0.0109
Brugia malayi Integrin beta pat-3 precursor 0.0327 0.0625 0.2328
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.004 0.0045 0.0168
Brugia malayi Tyrosine-protein kinase abl-1 0.0133 0.0233 0.0869
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0063 0.0093 0.0267
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0107 0.018 0.0517
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0033 0.0095
Loa Loa (eye worm) kelch domain-containing protein family protein 0.005 0.0065 0.0242
Brugia malayi CXXC zinc finger family protein 0.0088 0.0143 0.0532
Schistosoma mansoni vesicular amine transporter 0.0022 0.0009 0.0026
Schistosoma mansoni steroid hormone receptor ad4bp 0.0134 0.0236 0.0679
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.002 0.0005 0.0005
Schistosoma mansoni tubulin subunit alpha 0.0346 0.0664 0.1906
Mycobacterium ulcerans esterase/lipase LipP 0.0186 0.0341 0.5141
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0049 0.0064 0.0961
Echinococcus multilocularis expressed conserved protein 0.0666 0.131 0.131
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0 0.0001
Loa Loa (eye worm) glutaminase 0.0275 0.0519 0.1933
Onchocerca volvulus 0.0038 0.0041 0.0456
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0116 0.02 0.02
Plasmodium falciparum tubulin beta chain 0.1347 0.2685 1
Echinococcus granulosus tubulin beta 4A class IVa 0.1347 0.2685 0.7711
Loa Loa (eye worm) hypothetical protein 0.0071 0.0108 0.0403
Trypanosoma brucei trypanothione reductase 0.0049 0.0065 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0008
Schistosoma mansoni tyrosine kinase 0.005 0.0066 0.019
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0049 0.0064 0.0961
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0043 0.0123
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0 0.0001
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0015 0.0063
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0003 0.0014
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0228 0.0426 0.0426
Echinococcus granulosus expressed conserved protein 0.0666 0.131 0.3763
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Schistosoma mansoni hypothetical protein 0.0131 0.023 0.0662
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0026 0.0016 0.0047
Schistosoma mansoni nuclear hormone receptor 0.0063 0.0093 0.0267
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0099 0.0358
Loa Loa (eye worm) tubulin alpha chain 0.1007 0.1998 0.7444
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0186 0.0341 0.144
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0121 0.0209 0.0777
Leishmania major beta tubulin 0.1347 0.2685 1
Echinococcus multilocularis tubulin epsilon chain 0.081 0.1599 0.1599
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0162 0.0293 0.109
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0062 0.0177
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0162 0.0293 0.108
Loa Loa (eye worm) glutathione reductase 0.0049 0.0065 0.024
Echinococcus granulosus eukaryotic initiation factor 4A 0.0026 0.0016 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0026 0.0098
Brugia malayi nuclear receptor NHR-88 0.0063 0.0093 0.0345
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0134 0.0236 0.0679
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0025 0.0093
Brugia malayi hypothetical protein 0.0043 0.0052 0.0192
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0171 0.0311 0.0893
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.002 0.0005 0.0071
Trichomonas vaginalis tubulin beta chain, putative 0.1007 0.1998 0.7444
Schistosoma mansoni tubulin subunit beta 0.1347 0.2685 0.7711
Trichomonas vaginalis tubulin, putative 0.0401 0.0774 0.2883
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0153 0.0275 0.1022
Brugia malayi nuclear hormone receptor family member odr-7 0.0063 0.0093 0.0345
Loa Loa (eye worm) hypothetical protein 0.0186 0.0341 0.127
Brugia malayi conserved hypotetical protein 0.0063 0.0093 0.0345
Schistosoma mansoni coup transcription factor 0.0134 0.0236 0.0679
Trichomonas vaginalis tubulin beta chain, putative 0.1007 0.1998 0.7444
Plasmodium falciparum tubulin epsilon chain, putative 0.081 0.1599 0.5956
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0015 0.0224
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0055 0.0205
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0134 0.0236 0.088
Brugia malayi chromobox protein homolog 3 0.0039 0.0044 0.0164
Brugia malayi nuclear receptor NHR-67 0.0063 0.0093 0.0345
Onchocerca volvulus 0.0043 0.0052 0.0579
Echinococcus granulosus Tubulin beta 2C chain 0.1347 0.2685 0.7711
Schistosoma mansoni organic anion transporter 0.0058 0.0082 0.0237
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0134 0.0236 0.0236
Trichomonas vaginalis esterase, putative 0.0186 0.0341 0.1271
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0003 0.0009
Echinococcus multilocularis geminin 0.1742 0.3482 0.3482
Trichomonas vaginalis DNA helicase recq, putative 0.0033 0.0031 0.0114
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0 0.0001
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0015 0.0055
Onchocerca volvulus 0.0043 0.0052 0.0579
Onchocerca volvulus 0.004 0.0045 0.0505
Schistosoma mansoni lamin 0.0028 0.0022 0.0062
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0 0.0001
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0055 0.0206
Brugia malayi MH1 domain containing protein 0.0019 0.0003 0.0009
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0134 0.0236 0.0679
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0324 0.1207
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0015 0.0055
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Schistosoma mansoni integrin beta subunit 0.0193 0.0354 0.1016
Loa Loa (eye worm) hypothetical protein 0.0088 0.0143 0.0531
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0168
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Trichomonas vaginalis tubulin epsilon chain, putative 0.0346 0.0664 0.2472
Loa Loa (eye worm) hypothetical protein 0.0134 0.0236 0.088
Echinococcus multilocularis tubulin alpha 1C chain 0.1007 0.1998 0.1998
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0025 0.0093
Onchocerca volvulus Bile acid receptor homolog 0.0134 0.0236 0.2654
Echinococcus multilocularis c src tyrosine kinase 0.002 0.0005 0.0005
Brugia malayi Patched protein homolog 1 0.0043 0.0052 0.0192
Mycobacterium tuberculosis Probable lipase LipD 0.0186 0.0341 0.144
Loa Loa (eye worm) patched family protein 0.0043 0.0052 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0044 0.0165
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0003 0.0012
Trypanosoma cruzi tubulin gamma chain 0.081 0.1601 0.5962
Schistosoma mansoni integrin alpha-ps 0.0072 0.0109 0.0314
Loa Loa (eye worm) hypothetical protein 0.0058 0.0082 0.0306
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.0341 0.1271
Trichomonas vaginalis tubulin, putative 0.041 0.0792 0.2949
Leishmania major phosphopantetheinyl transferase-like protein 0.0049 0.0064 0.0237
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.0052 0.0192
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0026 0.0016 0.0183
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0062 0.0062
Mycobacterium tuberculosis Probable reductase 0.0113 0.0192 0.0812
Giardia lamblia Beta tubulin 0.1347 0.2685 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0134 0.0236 0.0679
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0071 0.0108 0.0108
Echinococcus granulosus nuclear receptor nhr 48 0.0063 0.0093 0.0267
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.005 0.0563
Trichomonas vaginalis penicillin-binding protein, putative 0.0186 0.0341 0.1271
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.0192 0.0812
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0075 0.0279
Loa Loa (eye worm) hypothetical protein 0.0373 0.0718 0.2673
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0063 0.0181
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0022 0.008
Entamoeba histolytica tubulin alpha-1 chain 0.1007 0.1998 0.7444
Loa Loa (eye worm) acetyltransferase 0.0152 0.0272 0.1013
Toxoplasma gondii alpha-tubulin I, putative 0.1007 0.1998 0.7444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.015
Schistosoma mansoni isocitrate dehydrogenase 0.002 0.0005 0.0014
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0086 0.0086
Trypanosoma cruzi tubulin delta chain 0.0684 0.1345 0.501
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.006 0.0222
Trichomonas vaginalis tubulin gamma chain, putative 0.081 0.1599 0.5957
Schistosoma mansoni integrin alpha 0.016 0.0287 0.0825
Loa Loa (eye worm) hypothetical protein 0.0174 0.0316 0.1178
Onchocerca volvulus 0.0088 0.0143 0.1607
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0134 0.0236 0.088
Schistosoma mansoni smad 0.0034 0.0033 0.0095
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.0218 0.0919
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0134 0.0236 0.0679
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0045 0.0045
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0048 0.0177
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0058 0.0082 0.0082
Brugia malayi Nuclear hormone receptor E75 0.0063 0.0093 0.0345
Schistosoma mansoni hypothetical protein 0.0296 0.0562 0.1613
Echinococcus granulosus ecdysone induced protein 78C 0.0134 0.0236 0.0679
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0134 0.0236 0.0236
Onchocerca volvulus 0.0028 0.0022 0.0242
Trypanosoma brucei zeta tubulin, putative 0.091 0.1803 0.6711
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0162 0.0293 0.0293
Echinococcus granulosus Smad4 0.0034 0.0033 0.0095
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.005 0.0066 0.019
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0015 0.0224
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0106
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0008
Echinococcus multilocularis tumor protein p63 0.0353 0.0677 0.0677
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0015 0.0224
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.002
Onchocerca volvulus 0.0058 0.0082 0.0925
Plasmodium vivax tubulin gamma chain, putative 0.081 0.1601 0.5962
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0168
Echinococcus granulosus agrin 0.004 0.0045 0.013
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.002 0.0005 0.0005
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0035 0.0132
Onchocerca volvulus 0.0063 0.0093 0.1042
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0028 0.0106
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0016 0.0061
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Echinococcus granulosus Nuclear hormone receptor HR96 0.0063 0.0093 0.0267
Loa Loa (eye worm) patched family protein 0.0043 0.0052 0.0192
Trypanosoma brucei tubulin gamma chain 0.081 0.1601 0.5958
Echinococcus multilocularis tubulin alpha chain 0.1007 0.1998 0.1998
Schistosoma mansoni tubulin subunit gamma 0.081 0.1601 0.4598
Echinococcus granulosus Tubulin alpha 1 chain 0.1007 0.1998 0.574
Schistosoma mansoni unc-13 (munc13) 0.002 0.0005 0.0014
Trichomonas vaginalis glutaminase, putative 0.0275 0.0519 0.1934
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0041 0.0151
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0193 0.0354 0.0354
Brugia malayi hypothetical protein 0.0239 0.0448 0.1666
Echinococcus granulosus Niemann Pick C1 protein 0.1014 0.2011 0.5777
Schistosoma mansoni tubulin subunit beta 0.1347 0.2685 0.7711
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Schistosoma mansoni tyrosine kinase 0.005 0.0066 0.019
Loa Loa (eye worm) hypothetical protein 0.0039 0.0043 0.0159
Loa Loa (eye worm) hypothetical protein 0.1007 0.1998 0.7444
Brugia malayi MH1 domain containing protein 0.0034 0.0033 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0021 0.0078
Brugia malayi CHE-14 protein 0.0304 0.0579 0.2158
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0015 0.0224
Onchocerca volvulus 0.0058 0.0082 0.0925
Brugia malayi hypothetical protein 0.0259 0.0488 0.1817
Echinococcus granulosus defective proboscis extension response 0.0022 0.0009 0.0026
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Schistosoma mansoni tubulin subunit alpha 0.1007 0.1998 0.574
Echinococcus granulosus tubulin alpha 0.0756 0.149 0.4281
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0065 0.024
Trichomonas vaginalis tubulin beta chain, putative 0.1007 0.1998 0.7444
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.003 0.0025 0.0025
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.006 0.021
Schistosoma mansoni thyroid hormone receptor 0.0266 0.0502 0.1441
Trypanosoma cruzi beta tubulin, putative 0.1347 0.2685 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0071 0.0108 0.0403
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0033 0.0095
Echinococcus granulosus neuroglian 0.0025 0.0015 0.0044
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.002 0.0005 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0099 0.0358
Giardia lamblia Beta tubulin 0.1347 0.2685 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.015
Onchocerca volvulus 0.0043 0.0052 0.0579
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0043 0.016
Schistosoma mansoni hypothetical protein 0.005 0.0067 0.0191
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0134 0.0236 0.088
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0063 0.0093 0.0345
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0002 0.0009
Schistosoma mansoni tubulin subunit alpha 0.1007 0.1998 0.574
Loa Loa (eye worm) nuclear receptor NHR-67 0.0063 0.0093 0.0345
Treponema pallidum ATP-dependent RNA helicase 0.0026 0.0016 0.0248
Echinococcus granulosus tubulin alpha 3 chain 0.1007 0.1998 0.574
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0086 0.0247
Schistosoma mansoni DNA helicase recq5 0.003 0.0025 0.0073
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0049 0.0064 0.0961
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0009 0.0026
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0093 0.0093
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0162 0.0293 0.109
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0153 0.0275 0.1022
Onchocerca volvulus 0.0043 0.0052 0.0579
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0016 0.006
Brugia malayi MH1 domain containing protein 0.0034 0.0033 0.0123
Loa Loa (eye worm) hypothetical protein 0.0186 0.0341 0.127
Schistosoma mansoni intermediate filament proteins 0.0028 0.0022 0.0062
Loa Loa (eye worm) beta-tubulin 0.1347 0.2685 1
Mycobacterium leprae conserved hypothetical protein 0.0186 0.0341 0.5141
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0 0.0001
Schistosoma mansoni lamin 0.0028 0.0022 0.0062
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Echinococcus granulosus integrin alpha ps 0.0034 0.0034 0.0098
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.002 0.0005 0.0017
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0015 0.0055
Echinococcus granulosus tyrosine protein kinase Src64B 0.005 0.0066 0.019
Echinococcus granulosus roundabout 2 0.0031 0.0028 0.008
Brugia malayi tailless protein 0.0063 0.0093 0.0345
Leishmania major beta tubulin 0.1347 0.2685 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0003 0.0012
Echinococcus multilocularis neuroglian 0.0025 0.0015 0.0015
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0063 0.0234
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.005 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0088 0.0143 0.0531
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0134 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Brugia malayi nuclear hormone receptor family member nhr-6 0.0063 0.0093 0.0345
Onchocerca volvulus Glucosylceramidase homolog 0.0178 0.0324 0.3641
Echinococcus granulosus tyrosine protein kinase Fyn 0.005 0.0066 0.019
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0022 0.008
Plasmodium falciparum thioredoxin reductase 0.0049 0.0065 0.024
Loa Loa (eye worm) TK protein kinase 0.0112 0.0191 0.0709
Schistosoma mansoni organic anion transporter 0.0058 0.0082 0.0237
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0062 0.0229
Mycobacterium tuberculosis Probable esterase LipL 0.0186 0.0341 0.144
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0065 0.024
Mycobacterium tuberculosis Probable lipase LipE 0.0186 0.0341 0.144
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0099 0.0358
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0055
Leishmania major beta tubulin 0.1347 0.2685 1
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0065 0.024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0099 0.0358
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0 0.0001
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0063 0.0234
Echinococcus granulosus lamin dm0 0.0028 0.0022 0.0062
Echinococcus granulosus tubulin beta 1 chain 0.1347 0.2685 0.7711
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.0341 0.1271
Loa Loa (eye worm) tubulin beta-1 chain 0.1347 0.2685 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0015 0.0055
Brugia malayi Niemann-Pick C1 protein precursor 0.0709 0.1397 0.5203
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0134 0.0236 0.088
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0037 0.004 0.0149
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0162 0.0293 0.108
Echinococcus multilocularis FTZ F1 alpha 0.0134 0.0236 0.0236
Onchocerca volvulus 0.0186 0.0341 0.3833
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.0272 0.0272
Echinococcus granulosus ATP dependent DNA helicase Q1 0.003 0.0025 0.0073
Mycobacterium leprae Probable lipase LipE 0.0186 0.0341 0.5141
Schistosoma mansoni tubulin subunit beta 0.1347 0.2685 0.7711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0016 0.006
Brugia malayi beta-lactamase family protein 0.0186 0.0341 0.127
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0343 0.1279
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0512 0.1908
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0016 0.0061
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0186 0.0341 0.127
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0134 0.0236 0.0679
Brugia malayi hypothetical protein 0.0071 0.0108 0.0403
Echinococcus multilocularis Smad4 0.0034 0.0033 0.0033
Plasmodium falciparum ataxin-2 like protein, putative 0.0259 0.0488 0.1817
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0027 0.002 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.001 0.0036
Brugia malayi SRC-1 0.005 0.0066 0.0246
Leishmania major eukaryotic initiation factor 4a, putative 0.0026 0.0016 0.0061
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.006 0.006
Trypanosoma cruzi epsilon tubulin, putative 0.081 0.1599 0.5956
Plasmodium falciparum lipid/sterol:H+ symporter 0.0043 0.0052 0.0192
Schistosoma mansoni cpg binding protein 0.0093 0.0153 0.044
Trichomonas vaginalis tubulin epsilon chain, putative 0.1347 0.2685 1
Echinococcus multilocularis lamin 0.0028 0.0022 0.0022
Brugia malayi protein C24B5.3 0.0043 0.0052 0.0192
Loa Loa (eye worm) MBCTL1 0.0055 0.0075 0.0279
Echinococcus granulosus histone acetyltransferase KAT2B 0.0148 0.0264 0.0757
Trichomonas vaginalis tubulin beta chain, putative 0.041 0.0792 0.2949
Loa Loa (eye worm) beta-lactamase 0.0186 0.0341 0.127
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0106
Schistosoma mansoni tubulin subunit alpha 0.1007 0.1998 0.574
Loa Loa (eye worm) tubulin alpha-2 chain 0.1007 0.1998 0.7444
Loa Loa (eye worm) tubulin gamma chain 0.081 0.1601 0.5962
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.002 0.0005 0.0017
Loa Loa (eye worm) steroid hormone receptor 0.0134 0.0236 0.088
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0168
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.025 0.0717
Mycobacterium tuberculosis Conserved protein 0.0186 0.0341 0.144
Trichomonas vaginalis chromobox protein, putative 0.0042 0.005 0.0187
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0134 0.0236 0.088
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Echinococcus granulosus cathepsin l1 0.0017 0 0.0001
Echinococcus multilocularis tubulin subunit beta 0.1347 0.2685 0.2685
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0028 0.0106
Toxoplasma gondii patched family protein 0.0043 0.0052 0.0192
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0071 0.0108 0.0311
Trichomonas vaginalis tubulin alpha chain, putative 0.041 0.0792 0.2949
Brugia malayi Patched related family protein 10 0.0043 0.0052 0.0192
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0045 0.0168
Entamoeba histolytica hypothetical protein 0.0075 0.0117 0.0435
Leishmania major beta tubulin 0.1347 0.2685 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Brugia malayi Patched related family protein 4 0.0043 0.0052 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.002
Schistosoma mansoni hypothetical protein 0.0108 0.0183 0.0526
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0104 0.0299
Echinococcus multilocularis tyrosine protein kinase Srms 0.0043 0.0052 0.0052
Brugia malayi secreted modular calcium-binding protein 1 0.004 0.0045 0.0168
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0343 0.1279
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0033
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0131 0.023 0.023
Leishmania major beta tubulin 0.1347 0.2685 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0134 0.0236 0.0236
Schistosoma mansoni tyrosine kinase 0.0109 0.0184 0.0529
Trypanosoma brucei hypothetical protein, conserved 0.0186 0.0341 0.126
Brugia malayi hypothetical protein 0.0043 0.0052 0.0192
Echinococcus multilocularis protein dispatched 1 0.0347 0.0666 0.0666
Trypanosoma brucei alpha tubulin 0.1007 0.1998 0.7441
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0043 0.0159
Echinococcus granulosus thyroid hormone receptor alpha 0.0063 0.0093 0.0267
Brugia malayi sodium-independent organic anion transporter family protein 0.0058 0.0082 0.0306
Brugia malayi nuclear hormone receptor 0.0063 0.0093 0.0345
Loa Loa (eye worm) hypothetical protein 0.0259 0.0488 0.1817
Echinococcus multilocularis follistatin 0.004 0.0045 0.0045
Trypanosoma brucei epsilon tubulin 0.0756 0.149 0.5546
Trypanosoma brucei alpha tubulin 0.1007 0.1998 0.7441
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0016 0.006
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0015 0.0224
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0134 0.0236 0.0679
Loa Loa (eye worm) tubulin alpha 2 0.0661 0.13 0.4841
Echinococcus multilocularis L aminoadipate semialdehyde 0.0174 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0058 0.0082 0.0306
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0134 0.0236 0.0679
Schistosoma mansoni hypothetical protein 0.0293 0.0557 0.1601
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0055 0.0205
Schistosoma mansoni integrin alpha-ps 0.0037 0.004 0.0115
Loa Loa (eye worm) tubulin beta chain 0.1347 0.2685 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0055 0.0206
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0045 0.0168
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.0218 0.0919
Schistosoma mansoni smad1 5 8 and 0.0034 0.0033 0.0095
Echinococcus multilocularis tyrosine protein kinase Src42A 0.005 0.0066 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0022 0.008
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0162 0.0293 0.0841
Schistosoma mansoni smad1 5 8 and 0.0034 0.0033 0.0095
Loa Loa (eye worm) histone methyltransferase 0.0027 0.002 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0324 0.1207
Echinococcus multilocularis integrin alpha ps 0.0072 0.0109 0.0109
Echinococcus granulosus tubulin alpha 1C chain 0.1007 0.1998 0.574
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0025 0.0015 0.0044
Loa Loa (eye worm) hypothetical protein 0.0028 0.0022 0.008
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.0052 0.0192
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0031 0.0114
Loa Loa (eye worm) hypothetical protein 0.017 0.0309 0.115
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0007 0.0025
Trichomonas vaginalis penicillin-binding protein, putative 0.0186 0.0341 0.1271
Giardia lamblia Sgs1 DNA helicase, putative 0.003 0.0025 0.0082
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.006 0.0171
Schistosoma mansoni nuclear hormone receptor 0.0063 0.0093 0.0267
Echinococcus multilocularis beta tubulin 0.1347 0.2685 0.2685
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0015 0.0055
Echinococcus multilocularis tubulin alpha chain 0.1007 0.1998 0.1998
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Brugia malayi sulfakinin receptor protein 0.0239 0.0448 0.1666
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0021 0.0078
Plasmodium falciparum alpha tubulin 1 0.1007 0.1998 0.7444
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0709 0.1397 0.5203
Brugia malayi Cell division protein ftsZ 0.0346 0.0664 0.2471
Echinococcus granulosus Tubulin beta 2C chain 0.1347 0.2685 0.7711
Echinococcus granulosus tyrosine protein kinase Fyn 0.005 0.0066 0.019
Brugia malayi Protein kinase domain containing protein 0.0104 0.0174 0.0647
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0661 0.13 0.4841
Echinococcus granulosus tyrosine kinase 0.0043 0.0052 0.015
Echinococcus multilocularis tyrosine protein kinase Fyn 0.005 0.0066 0.0066
Loa Loa (eye worm) TK protein kinase 0.0036 0.0038 0.0141
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Leishmania major cathepsin L-like protease 0.0067 0.0099 0.037
Leishmania major beta tubulin 0.1347 0.2685 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Toxoplasma gondii patched family protein 0.0043 0.0052 0.0192
Echinococcus granulosus L aminoadipate semialdehyde 0.0174 0.0316 0.0909
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Loa Loa (eye worm) isocitrate dehydrogenase 0.0162 0.0293 0.109
Echinococcus multilocularis Niemann Pick C1 protein 0.0709 0.1397 0.1397
Schistosoma mansoni hypothetical protein 0.0049 0.0063 0.0181
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0022 0.008
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0134 0.0236 0.088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0021 0.0078
Echinococcus multilocularis Tubulin alpha 1 chain 0.1007 0.1998 0.1998
Loa Loa (eye worm) alpha-tubulin 0.1007 0.1998 0.7444
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0104 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.002
Echinococcus multilocularis expressed protein 0.004 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.003 0.0025 0.0093
Brugia malayi isocitrate dehydrogenase 0.0162 0.0293 0.109
Trypanosoma brucei beta tubulin 0.1347 0.2685 1
Schistosoma mansoni survival motor neuron protein 0.005 0.0067 0.0191
Onchocerca volvulus 0.0028 0.0022 0.0242
Brugia malayi hypothetical protein 0.0247 0.0463 0.1726
Schistosoma mansoni alpha tubulin 0.1007 0.1998 0.574
Trypanosoma brucei alpha tubulin, putative 0.041 0.0792 0.294
Trichomonas vaginalis conserved hypothetical protein 0.0304 0.0579 0.2158
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0015 0.0055
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0058 0.0082 0.0306
Plasmodium vivax tubulin epsilon chain, putative 0.081 0.1599 0.5956
Trichomonas vaginalis tubulin, putative 0.041 0.0792 0.2949
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.005 0.0066 0.0066
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0106 0.0396
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0015 0.0055
Toxoplasma gondii beta-1 tubulin, putative 0.1347 0.2685 1
Brugia malayi Isocitrate dehydrogenase 0.0162 0.0293 0.109
Echinococcus multilocularis tyrosine protein kinase Fyn 0.005 0.0066 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0134 0.0236 0.088
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0071 0.0262
Echinococcus granulosus tyrosine protein kinase Btk29A 0.002 0.0005 0.0013
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0186 0.0341 0.098
Schistosoma mansoni cell adhesion molecule 0.0028 0.0021 0.0062
Echinococcus multilocularis cpg binding protein 0.0093 0.0153 0.0153
Plasmodium vivax tubulin alpha chain, putative 0.1007 0.1998 0.7444
Loa Loa (eye worm) ATP-dependent DNA helicase 0.003 0.0025 0.0093
Plasmodium falciparum tubulin gamma chain 0.081 0.1601 0.5962
Loa Loa (eye worm) hypothetical protein 0.0058 0.0082 0.0306
Schistosoma mansoni alpha tubulin 0.1007 0.1998 0.574
Mycobacterium ulcerans lipase LipD 0.0186 0.0341 0.5141
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0346 0.0664 1
Brugia malayi Patched family protein 0.0043 0.0052 0.0192
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0598 0.1172 0.4364
Mycobacterium ulcerans hypothetical protein 0.0025 0.0015 0.0224
Schistosoma mansoni tubulin subunit beta 0.0346 0.0664 0.1906
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.0463 0.1331
Echinococcus granulosus geminin 0.1742 0.3482 1
Brugia malayi steroid hormone receptor 0.0134 0.0236 0.088
Onchocerca volvulus 0.0052 0.0069 0.0775
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Leishmania major alpha tubulin 0.1007 0.1998 0.7444
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0108 0.0403
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0324 0.1207
Onchocerca volvulus Protein patched homolog 0.0043 0.0052 0.0579
Onchocerca volvulus 0.0186 0.0341 0.3833
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0134 0.0236 0.0236
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0043 0.0123
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.001 0.0036
Brugia malayi Thioredoxin reductase 0.0049 0.0065 0.024
Trichomonas vaginalis tubulin gamma chain, putative 0.0346 0.0664 0.2472
Echinococcus multilocularis Niemann Pick C1 protein 0.1014 0.2011 0.2011
Echinococcus granulosus bloom syndrome protein 0.0043 0.0052 0.0148
Plasmodium falciparum alpha tubulin 2 0.1007 0.1998 0.7444
Echinococcus multilocularis GPCR, family 2 0.0049 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0192
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.006 0.0221
Brugia malayi MH1 domain containing protein 0.0019 0.0003 0.0009
Echinococcus multilocularis integrin alpha 3 0.0122 0.0212 0.0212
Brugia malayi sodium-independent organic anion transporter family protein 0.0058 0.0082 0.0306
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0044 0.0495
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0104 0.0299
Brugia malayi Integrin alpha pat-2 precursor 0.016 0.0287 0.107
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0345
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0026 0.0016 0.0049
Toxoplasma gondii tubulin, putative 0.0054 0.0074 0.0273
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0104 0.0387
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0043 0.0148
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0075 0.0216
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0067 0.0247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0021 0.0078
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0075 0.0216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0016 0.006
Schistosoma mansoni nuclear receptor 0.0063 0.0093 0.0267
Echinococcus multilocularis Immunoglobulin 0.0022 0.0009 0.0009
Schistosoma mansoni RAR-like nuclear receptor 0.0134 0.0236 0.0679
Leishmania major beta tubulin 0.1347 0.2685 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 14.6 nM Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometry ChEMBL. 18954042
IC50 (binding) = 1810 nM Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHOK1 cells by liquid scintillation spectrometry ChEMBL. 18954042

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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