Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.4278 | 0.4242 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0203 | 0.466 | 0.4626 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0136 | 0.216 | 0.2197 |
Echinococcus multilocularis | jun protein | 0.0085 | 0.0256 | 0.0202 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0063 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.914 | 0.9135 |
Toxoplasma gondii | AGC kinase | 0.0079 | 0.0063 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 0.6354 | 0.633 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0085 | 0.0256 | 0.0202 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0063 | 1 |
Brugia malayi | protein kinase C II. | 0.0278 | 0.7425 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0063 | 1 |
Echinococcus multilocularis | protein kinase c iota type | 0.0135 | 0.2138 | 0.2174 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.7065 | 0.7046 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0171 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.7065 | 0.7046 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0063 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0063 | 1 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0193 | 0.4278 | 0.4417 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0063 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0079 | 0.0063 | 0.5 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0337 | 0.9607 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0278 | 0.7425 | 0.7714 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0214 | 0.5032 | 0.5206 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0063 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0337 | 0.9607 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0063 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.0135 | 0.2138 | 0.2174 |
Schistosoma mansoni | atypical protein kinase C | 0.0135 | 0.2138 | 0.2174 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0278 | 0.7425 | 0.7714 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0193 | 0.4278 | 0.4417 |
Echinococcus granulosus | protein kinase C gamma type | 0.0281 | 0.7532 | 0.7826 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0136 | 0.216 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0063 | 1 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0193 | 0.4278 | 0.4417 |
Echinococcus granulosus | jun protein | 0.0085 | 0.0256 | 0.0202 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0281 | 0.7532 | 0.7826 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0278 | 0.7425 | 0.7714 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0337 | 0.9607 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0063 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.7065 | 0.7046 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0337 | 0.9607 | 1 |
Onchocerca volvulus | 0.0268 | 0.7065 | 0.5 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0085 | 0.0256 | 0.0202 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0063 | 1 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0278 | 0.7425 | 0.7408 |
Brugia malayi | bZIP transcription factor family protein | 0.0085 | 0.0256 | 0.0262 |
Brugia malayi | Protein kinase c protein 2 | 0.026 | 0.6735 | 0.9063 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.