Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0143 | 0.1603 | 0.267 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0334 | 0.0557 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0047 | 0.036 | 0.2246 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0065 | 0.0599 | 0.0706 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0077 | 0.0752 | 0.1254 |
Entamoeba histolytica | poly(ADP-ribose) polymerase, putative | 0.0143 | 0.1603 | 1 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.0925 | 0.0925 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0065 | 0.0599 | 0.2196 |
Mycobacterium ulcerans | pyruvate kinase | 0.0065 | 0.0599 | 0.0998 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0183 | 0.0304 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.029 | 0.0483 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0022 | 0.0043 | 0.0072 |
Echinococcus granulosus | pyruvate kinase | 0.0033 | 0.0189 | 0.0315 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.1016 | 0.1692 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0155 | 0.0155 |
Echinococcus granulosus | WGR domain containing protein | 0.0044 | 0.033 | 0.0549 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.036 | 0.2246 |
Echinococcus granulosus | poly ADP ribose polymerase 1 | 0.0143 | 0.1603 | 0.267 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0189 | 0.0189 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0211 | 0.1315 |
Echinococcus granulosus | pyruvate kinase | 0.0033 | 0.0189 | 0.0315 |
Onchocerca volvulus | 0.0077 | 0.0752 | 0.0696 | |
Loa Loa (eye worm) | pyruvate kinase | 0.0065 | 0.0599 | 0.0998 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0155 | 0.0258 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0334 | 0.0334 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0599 | 0.0998 |
Brugia malayi | Blistered cuticle protein 3 | 0.0077 | 0.0752 | 0.1254 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0065 | 0.0599 | 0.0424 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0158 | 0.1799 | 0.2771 |
Echinococcus granulosus | pyruvate kinase | 0.0065 | 0.0599 | 0.0998 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0211 | 0.1315 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0047 | 0.036 | 0.06 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.041 | 0.0683 |
Giardia lamblia | Pyruvate kinase | 0.0033 | 0.0189 | 0.3152 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0482 | 0.6001 | 1 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0482 | 0.6001 | 1 |
Echinococcus granulosus | thymidylate synthase | 0.0482 | 0.6001 | 1 |
Mycobacterium ulcerans | thymidylate synthase | 0.0482 | 0.6001 | 1 |
Brugia malayi | Pyruvate kinase, alpha/beta domain containing protein | 0.002 | 0.0011 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0207 | 0.0345 |
Echinococcus multilocularis | poly (ADP ribose) polymerase | 0.0033 | 0.018 | 0.018 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0617 | 0.1028 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0271 | 0.0451 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0077 | 0.0752 | 0.0696 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0344 | 0.0573 |
Chlamydia trachomatis | pyruvate kinase | 0.0065 | 0.0599 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0077 | 0.0752 | 0.1254 |
Brugia malayi | Animal haem peroxidase family protein | 0.0077 | 0.0752 | 0.1254 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0482 | 0.6001 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0155 | 0.0258 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.036 | 0.06 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0211 | 0.1315 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0098 | 0.1019 | 0.1698 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Schistosoma mansoni | pyruvate kinase | 0.0065 | 0.0599 | 0.0998 |
Brugia malayi | Animal haem peroxidase family protein | 0.0077 | 0.0752 | 0.1254 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0211 | 0.0211 |
Brugia malayi | hypothetical protein | 0.0229 | 0.2727 | 0.4544 |
Brugia malayi | WGR domain containing protein | 0.0078 | 0.0771 | 0.1284 |
Echinococcus multilocularis | peroxidasin | 0.0077 | 0.0752 | 0.0752 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0077 | 0.0752 | 0.1254 |
Brugia malayi | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0035 | 0.0207 | 0.0032 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0334 | 0.0557 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0183 | 0.0304 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.029 | 0.0483 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.0925 | 0.154 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0137 | 0.1534 | 0.2556 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0047 | 0.036 | 0.06 |
Brugia malayi | Animal haem peroxidase family protein | 0.0077 | 0.0752 | 0.1254 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0617 | 0.1028 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.029 | 0.0483 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0334 | 0.0557 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0078 | 0.0771 | 0.1284 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.036 | 0.06 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0334 | 0.0557 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0155 | 0.0258 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0155 | 0.0258 |
Onchocerca volvulus | 0.0482 | 0.6001 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0155 | 0.0258 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.029 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0207 | 0.0345 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0077 | 0.0752 | 0.1254 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0482 | 0.6001 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0077 | 0.0752 | 0.0696 |
Schistosoma mansoni | pyruvate kinase | 0.0065 | 0.0599 | 0.0998 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0078 | 0.0771 | 0.1284 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1 | 0.1666 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0334 | 0.0557 |
Loa Loa (eye worm) | poly(ADP-ribose) polymerase | 0.0056 | 0.0484 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Entamoeba histolytica | hypothetical protein | 0.0022 | 0.0043 | 0.0268 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0047 | 0.036 | 0.06 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0229 | 0.2727 | 0.4544 |
Echinococcus multilocularis | thymidylate synthase | 0.0482 | 0.6001 | 0.6001 |
Echinococcus granulosus | pyruvate kinase | 0.0065 | 0.0599 | 0.0998 |
Echinococcus multilocularis | pyruvate kinase | 0.0065 | 0.0599 | 0.0599 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0482 | 0.6001 | 1 |
Brugia malayi | thymidylate synthase | 0.0482 | 0.6001 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1162 | 0.1936 |
Onchocerca volvulus | Peroxidase homolog | 0.0077 | 0.0752 | 0.0696 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0045 | 0.0344 | 0.0573 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0482 | 0.6001 | 1 |
Onchocerca volvulus | 0.0077 | 0.0752 | 0.0696 | |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0097 | 0.1016 | 0.1692 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0229 | 0.2727 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0077 | 0.0752 | 0.1254 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0044 | 0.033 | 0.0549 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0211 | 0.0351 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0229 | 0.2727 | 0.4544 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.036 | 0.06 |
Onchocerca volvulus | Dual oxidase homolog | 0.0077 | 0.0752 | 0.0696 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0035 | 0.0207 | 0.0345 |
Onchocerca volvulus | Peroxidase homolog | 0.0077 | 0.0752 | 0.0696 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0482 | 0.6001 | 1 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0078 | 0.0771 | 0.1284 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.036 | 0.06 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.036 | 0.06 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.1 | 0.6239 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0155 | 0.0155 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.036 | 0.06 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0065 | 0.0599 | 0.0424 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0334 | 0.0557 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0065 | 0.0599 | 0.2196 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0271 | 0.0451 |
Leishmania major | pyruvate kinase | 0.0065 | 0.0599 | 0.0998 |
Echinococcus multilocularis | pyruvate kinase | 0.0065 | 0.0599 | 0.0599 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0065 | 0.0599 | 0.0998 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0065 | 0.0599 | 0.0998 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0155 | 0.0258 |
Schistosoma mansoni | peroxidasin | 0.0077 | 0.0752 | 0.1254 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0065 | 0.0599 | 0.0998 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0155 | 0.0258 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0035 | 0.0207 | 0.0032 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.1 | 0.1666 |
Schistosoma mansoni | pyruvate kinase | 0.0033 | 0.0189 | 0.0315 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0207 | 0.0345 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.029 | 0.0483 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0183 | 0.0304 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0334 | 0.0334 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0065 | 0.0599 | 0.0998 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0482 | 0.6001 | 1 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.029 | 0.029 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.036 | 0.06 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0155 | 0.0258 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.029 | 0.029 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0065 | 0.0599 | 0.0998 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.029 | 0.1063 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0047 | 0.036 | 0.06 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0066 | 0.0617 | 0.1028 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0047 | 0.036 | 0.06 |
Plasmodium vivax | pyruvate kinase, putative | 0.0065 | 0.0599 | 0.0706 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0097 | 0.1016 | 0.1692 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0155 | 0.0258 |
Echinococcus granulosus | pyruvate kinase | 0.0033 | 0.0189 | 0.0315 |
Loa Loa (eye worm) | pyruvate kinase | 0.0065 | 0.0599 | 0.0998 |
Onchocerca volvulus | 0.0077 | 0.0752 | 0.0696 | |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0022 | 0.0043 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0771 | 0.1284 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0047 | 0.036 | 0.06 |
Schistosoma mansoni | peroxidasin | 0.0077 | 0.0752 | 0.1254 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.1 | 0.1666 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0077 | 0.0752 | 0.1254 |
Echinococcus multilocularis | poly (ADP ribose) polymerase 1 | 0.0143 | 0.1603 | 0.1603 |
Plasmodium falciparum | pyruvate kinase | 0.0065 | 0.0599 | 0.0706 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0183 | 0.0304 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0065 | 0.0599 | 0.0424 |
Loa Loa (eye worm) | thymidylate synthase | 0.0482 | 0.6001 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0207 | 0.0345 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0189 | 0.0189 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0035 | 0.0207 | 0.0345 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.036 | 0.06 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0068 | 0.0634 | 0.1056 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.036 | 0.2246 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0045 | 0.0344 | 0.2146 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0065 | 0.0599 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.036 | 0.06 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.029 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0097 | 0.1016 | 0.1692 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.036 | 0.06 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0022 | 0.0043 | 0.0072 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.036 | 0.06 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0211 | 0.0351 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.1 | 0.1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0155 | 0.0258 |
Echinococcus multilocularis | pyruvate kinase | 0.0051 | 0.0421 | 0.0421 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0334 | 0.0557 |
Mycobacterium ulcerans | hypothetical protein | 0.0047 | 0.036 | 0.06 |
Brugia malayi | WGR domain containing protein | 0.0143 | 0.1603 | 0.267 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0207 | 0.0345 |
Onchocerca volvulus | Peroxidasin homolog | 0.0077 | 0.0752 | 0.0696 |
Echinococcus granulosus | peroxidasin | 0.0077 | 0.0752 | 0.1254 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0065 | 0.0599 | 0.0998 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0189 | 0.0189 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0271 | 0.0451 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0211 | 0.1315 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0211 | 0.0351 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0482 | 0.6001 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0211 | 0.0351 |
Giardia lamblia | Pyruvate kinase | 0.0065 | 0.0599 | 1 |
Leishmania major | pyruvate kinase | 0.0065 | 0.0599 | 0.0998 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.036 | 0.06 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0752 | 0.1254 |
Echinococcus multilocularis | poly (adp ribose) polymerase 2 | 0.0078 | 0.0771 | 0.0771 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0155 | 0.0258 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0271 | 0.0451 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0155 | 0.0155 |
Brugia malayi | Peroxidasin | 0.0077 | 0.0752 | 0.1254 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0365 | 0.0365 |
Brugia malayi | Animal haem peroxidase family protein | 0.0077 | 0.0752 | 0.1254 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0137 | 0.1534 | 0.1534 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0065 | 0.0599 | 0.0998 |
Trypanosoma brucei | poly(adp-ribose) polymerase | 0.0078 | 0.0771 | 0.1284 |
Echinococcus granulosus | poly adp ribose polymerase 2 | 0.0078 | 0.0771 | 0.1284 |
Loa Loa (eye worm) | pyruvate kinase | 0.0065 | 0.0599 | 0.0998 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 155 % | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 10 uM by MTT assay | ChEMBL. | 19233646 |
Inhibition (binding) | = 48 % | Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells at 10 uM by enzyme immunoassay | ChEMBL. | 19233646 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.