Detailed information for compound 993926

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 400.425 | Formula: C21H24N2O6
  • H donors: 4 H acceptors: 5 LogP: 3.04 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)[C@@H](NC(=O)c1cccc(c1O)O)CCCCNC(=O)c1ccccc1
  • InChi: 1S/C21H24N2O6/c1-29-21(28)16(23-20(27)15-10-7-12-17(24)18(15)25)11-5-6-13-22-19(26)14-8-3-2-4-9-14/h2-4,7-10,12,16,24-25H,5-6,11,13H2,1H3,(H,22,26)(H,23,27)/t16-/m0/s1
  • InChiKey: KEZKOJMRVIOPCC-INIZCTEOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica protein kinase domain containing protein 0.0175 0.0595 1
Brugia malayi Bromodomain containing protein 0.0038 0.0096 0.0096
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0013 0.0004 0.0062
Mycobacterium ulcerans oxidoreductase 0.0031 0.007 0.007
Brugia malayi Bromodomain containing protein 0.0088 0.0277 0.0277
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.003 0.1105
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0013 0.0004 0.0004
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0064 0.0137
Loa Loa (eye worm) phosphofructokinase 0.0108 0.035 0.035
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0026 0.0333
Echinococcus granulosus aldo keto reductase 0.0031 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0004
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0073 0.0073
Echinococcus multilocularis Niemann Pick C1 protein 0.114 0.4092 0.4092
Plasmodium falciparum sentrin-specific protease 1 0.0045 0.0122 0.4552
Echinococcus granulosus bloom syndrome protein 0.002 0.003 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0087 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0034 0.0034
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.007 0.007
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0118 0.0386 0.0386
Echinococcus granulosus flap endonuclease 1 0.0026 0.0052 0.0052
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0191 0.065 0.065
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0087 0.2493
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.007 0.015
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0079 0.0245 0.3122
Echinococcus granulosus expressed protein 0.0032 0.0076 0.0076
Entamoeba histolytica deoxycytidyl transferase, putative 0.0067 0.0202 0.3394
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0064 0.2385
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0064 0.2385
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0067 0.0202 0.0202
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.007 0.007
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.2768 1 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0131 0.0435 0.0435
Echinococcus granulosus lysine specific demethylase 5A 0.0223 0.0765 0.0765
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0013 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0137 0.0137
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.003 0.003
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0087 0.0187
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0013 0.0004 0.0008
Loa Loa (eye worm) RecQ helicase 0.002 0.003 0.003
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0064 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0394 0.0394
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.007 0.007
Schistosoma mansoni jumonji domain containing protein 0.034 0.1191 0.1191
Loa Loa (eye worm) hypothetical protein 0.114 0.4092 0.4092
Echinococcus multilocularis transcription factor Dp 1 0.0076 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0042 0.0111 0.0111
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.003 0.1105
Brugia malayi mbt repeat family protein 0.0047 0.013 0.013
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0087 0.0187
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0013 0.0004 0.0004
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0087 0.1115
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0022 0.0022
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0154 0.0154
Entamoeba histolytica protein kinase, putative 0.0175 0.0595 1
Echinococcus multilocularis jumonji domain containing protein 0.0119 0.0391 0.0391
Onchocerca volvulus 0.0013 0.0004 0.006
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0154 0.0154
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.007 0.007
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.003 0.0064
Echinococcus granulosus microtubule associated protein 2 0.0686 0.2448 0.2448
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.003 0.003
Toxoplasma gondii PHD-finger domain-containing protein 0.0086 0.0269 1
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.013 0.013
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.013 0.013
Entamoeba histolytica aldose reductase, putative 0.0031 0.007 0.118
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0091 0.0196
Plasmodium vivax hypothetical protein, conserved 0.0028 0.006 0.2222
Brugia malayi beta-lactamase family protein 0.0036 0.0087 0.0087
Trypanosoma brucei DNA polymerase IV, putative 0.0107 0.0346 0.0346
Echinococcus multilocularis JmjC domain containing protein 4 0.0059 0.0172 0.0172
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.2768 1 1
Echinococcus granulosus JmjC domain containing protein 4 0.0059 0.0172 0.0172
Trichomonas vaginalis sentrin/sumo-specific protease, senp8, putative 0.0013 0.0004 0.0008
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.035 0.5891
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0013 0.0004 0.0062
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.007 0.007
Schistosoma mansoni jumonji/arid domain-containing protein 0.0223 0.0765 0.0765
Schistosoma mansoni ap endonuclease 0.0019 0.0026 0.0026
Brugia malayi 6-phosphofructokinase 0.0108 0.035 0.035
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.007 0.015
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.1299 0.4669 1
Treponema pallidum hypothetical protein 0.0022 0.0039 0.0415
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0154 0.0154
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.003 0.003
Entamoeba histolytica aldose reductase, putative 0.0031 0.007 0.118
Mycobacterium leprae Probable lipase LipE 0.0036 0.0087 0.2493
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0026 0.0026
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0154 0.0154
Brugia malayi Bromodomain containing protein 0.0074 0.0227 0.0227
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.007 0.007
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0091 0.1538
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0087 0.0187
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0131 0.0435 0.0435
Schistosoma mansoni ap endonuclease 0.0019 0.0026 0.0026
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0013 0.0004 0.0137
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0064 0.0137
Plasmodium vivax sentrin-specific protease 1, putative 0.0045 0.0122 0.4552
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0026 0.0026
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0091 0.0196
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0034 0.0034
Leishmania major hypothetical protein, conserved 0.0036 0.0087 0.0087
Onchocerca volvulus 0.0031 0.007 0.1152
Brugia malayi 6-phosphofructokinase 0.0108 0.035 0.035
Trypanosoma cruzi DNA damage repair protein, putative 0.0021 0.0034 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0226 0.0226
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0087 0.0087
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0087 0.0087
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0045 0.0122 0.0122
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.006 0.2222
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0026 0.0969
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.0595 0.0595
Loa Loa (eye worm) jmjC domain-containing protein 0.0223 0.0765 0.0765
Trypanosoma cruzi DNA damage repair protein, putative 0.0021 0.0034 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0394 0.0394
Brugia malayi jmjC domain containing protein 0.0397 0.14 0.14
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0032 0.0074 0.0074
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0087 0.1115
Brugia malayi Inositol-1 0.0037 0.0091 0.0091
Brugia malayi ImpB/MucB/SamB family protein 0.0093 0.0294 0.0294
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0067 0.0202 0.0202
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0036 0.0087 0.0087
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.0386 0.0386
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.008 0.0249 0.3185
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0172 0.0172
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0021 0.0034 0.1258
Echinococcus granulosus PHD finger protein rhinoceros 0.0086 0.0269 0.0269
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.114 0.4092 0.4092
Loa Loa (eye worm) Ulp1 protease 0.0013 0.0004 0.0004
Echinococcus multilocularis dna polymerase eta 0.0093 0.0294 0.0294
Trypanosoma brucei DNA polymerase IV, putative 0.012 0.0394 0.0394
Loa Loa (eye worm) hypothetical protein 0.004 0.0104 0.0104
Mycobacterium ulcerans hypothetical protein 0.0021 0.0034 0.0034
Schistosoma mansoni protein phosphatase 2C 0.0059 0.0172 0.0172
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0087 0.1115
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.007 0.015
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0013 0.0004 0.0137
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0064 1
Echinococcus granulosus aldo keto reductase 0.0031 0.007 0.007
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0059 0.0172 0.0172
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0087 0.3248
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.2768 1 1
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0019 0.0019
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.035 0.075
Schistosoma mansoni pol-related 0.0031 0.007 0.007
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.003 0.1105
Echinococcus multilocularis protein patched 0.114 0.4092 0.4092
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0034 0.0081 0.3028
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.035 0.075
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0087 0.0187
Schistosoma mansoni phd/f-box containing protein 0.0059 0.0172 0.0172
Echinococcus granulosus dna polymerase eta 0.0093 0.0294 0.0294
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0091 0.0091
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Echinococcus multilocularis bloom syndrome protein 0.002 0.003 0.003
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0061 0.0179 0.0179
Brugia malayi PHD-finger family protein 0.0086 0.0269 0.0269
Echinococcus multilocularis dna polymerase kappa 0.012 0.0394 0.0394
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0028 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0028 0.006 0.006
Schistosoma mansoni inositol monophosphatase 0.0037 0.0091 0.0091
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.003 0.003
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0028 0.006 0.2222
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.018 0.0609 1
Trichomonas vaginalis conserved hypothetical protein 0.114 0.4092 0.8765
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0052 0.0877
Plasmodium vivax sentrin-specific protease 2, putative 0.0013 0.0004 0.0137
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0013 0.0004 0.0008
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.007 0.007
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0013 0.0004 0.0004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0087 0.0087
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.035 0.035
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0028 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0047 0.013 0.013
Toxoplasma gondii ABC1 family protein 0.0036 0.0087 0.3248
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.007 0.015
Trypanosoma brucei unspecified product 0.0046 0.0126 0.0126
Leishmania major aldo-keto reductase-like protein 0.0031 0.007 0.007
Brugia malayi PHD-finger family protein 0.003 0.0067 0.0067
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0091 0.0091
Loa Loa (eye worm) inositol-1 0.0037 0.0091 0.0091
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.035 0.075
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.007 0.007
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0039 0.0039
Echinococcus multilocularis aldo keto reductase 0.0031 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0332 0.1163 0.1163
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0013 0.0004 0.0008
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Plasmodium falciparum phd finger protein, putative 0.0086 0.0269 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0212 0.0212
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.003 0.003
Onchocerca volvulus 0.0031 0.007 0.1152
Onchocerca volvulus 0.0031 0.007 0.1152
Loa Loa (eye worm) beta-lactamase 0.0036 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0175 0.0591 0.0591
Onchocerca volvulus 0.0036 0.0087 0.1433
Loa Loa (eye worm) hypothetical protein 0.0093 0.0294 0.0294
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.007 0.007
Echinococcus granulosus tumor protein p63 0.0336 0.1177 0.1177
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0013 0.0004 0.0062
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.035 0.035
Trypanosoma brucei DNA polymerase eta, putative 0.0093 0.0294 0.0294
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0026 0.0026
Schistosoma mansoni bromodomain containing protein 0.0063 0.0185 0.0185
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0052 0.1939
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0026 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0394 0.0394
Onchocerca volvulus 0.0047 0.013 0.2138
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0019
Schistosoma mansoni flap endonuclease-1 0.0023 0.0043 0.0043
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.013 0.2138
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.035 0.5891
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0167 0.0565 0.1211
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0806 0.2884 0.2884
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0394 0.0394
Brugia malayi AF-10 protein 0.0028 0.006 0.006
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0013 0.0004 0.0008
Echinococcus granulosus sentrin specific protease 8 0.0013 0.0004 0.0004
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0059 0.0172 0.6383
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0052 0.0052
Loa Loa (eye worm) oxidoreductase 0.0031 0.007 0.007
Onchocerca volvulus 0.0036 0.0087 0.1433
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0059 0.0172 0.0172
Echinococcus multilocularis aldehyde reductase 0.0022 0.0038 0.0038
Echinococcus multilocularis PHD finger protein rhinoceros 0.0086 0.0269 0.0269
Brugia malayi ImpB/MucB/SamB family protein 0.0067 0.0202 0.0202
Plasmodium vivax DNA repair protein REV1, putative 0.0021 0.0034 0.1258
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.007 0.015
Onchocerca volvulus 0.0031 0.007 0.1152
Trypanosoma brucei SUMO1/Ulp2, putative 0.0013 0.0004 0.0004
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.035 0.035
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.003 0.0064
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0064 0.2385
Loa Loa (eye worm) hypothetical protein 0.0045 0.0122 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0019 0.0019
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0013 0.0004 0.0008
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0087 0.0087
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0057 0.0163 0.0163
Mycobacterium tuberculosis Conserved protein 0.0036 0.0087 0.1115
Mycobacterium ulcerans hypothetical protein 0.0027 0.0057 0.0057
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0118 0.0386 0.0386
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0028 0.006 0.2222
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.013 0.013
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Schistosoma mansoni inositol monophosphatase 0.0037 0.0091 0.0091
Plasmodium falciparum flap endonuclease 1 0.0026 0.0052 0.1939
Echinococcus multilocularis aldo keto reductase 0.0031 0.007 0.007
Giardia lamblia PHD finger protein 15 0.0086 0.0269 0.0576
Loa Loa (eye worm) hypothetical protein 0.0031 0.007 0.007
Brugia malayi polk-prov protein 0.0074 0.0226 0.0226
Echinococcus granulosus sentrin specific protease 1 0.0045 0.0122 0.0122
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Loa Loa (eye worm) hypothetical protein 0.0036 0.0087 0.0087
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.007 0.007
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0073 0.0073
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.0386 0.0386
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.003 0.003
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.007 0.007
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.003 0.0064
Loa Loa (eye worm) MBCTL1 0.0054 0.0154 0.0154
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.007 0.007
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0087 0.1115
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0091 0.0091
Echinococcus granulosus peregrin 0.0088 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0036 0.0087 0.0087
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0175 0.0595 0.0595
Schistosoma mansoni hypothetical protein 0.0086 0.0269 0.0269
Mycobacterium ulcerans hypothetical protein 0.0036 0.0087 0.0087
Echinococcus multilocularis dual specificity 0.0175 0.0595 0.0595
Echinococcus granulosus phd:f box containing protein 0.0059 0.0172 0.0172
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0067 0.0202 0.0202
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.013 0.013
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0013 0.0004 0.0008
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.007 0.007
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.007 0.007
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0087 0.0087
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0013 0.0004 0.0004
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.035 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0067 0.0202 0.0202
Toxoplasma gondii PHD-finger domain-containing protein 0.0086 0.0269 1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0052 0.0052
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0064 0.1078
Schistosoma mansoni niemann-pick C1 (NPC1) 0.114 0.4092 0.4092
Giardia lamblia DNA damage repair protein 0.0021 0.0034 0.0072
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0013 0.0004 0.0004
Echinococcus granulosus lysine specific demethylase 6a 0.0059 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0172
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.003 0.003
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0039 0.0039
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.003 0.1105
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0172 0.0172
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0172 0.0172
Brugia malayi jmjC domain containing protein 0.0059 0.0172 0.0172
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0064 0.0137
Echinococcus granulosus Niemann Pick C1 protein 0.114 0.4092 0.4092
Schistosoma mansoni DNA polymerase IV / kappa 0.0021 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0004 0.0008
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0079 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.003 0.0067 0.0067
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.2768 1 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0064 0.1175
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0052 0.0052
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0019 0.0019
Echinococcus multilocularis expressed protein 0.0032 0.0076 0.0076
Brugia malayi phosphofructokinase 0.0108 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.2768 1 1
Schistosoma mansoni phosphatidylserine receptor 0.0059 0.0172 0.0172
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.035 0.035
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.007 0.007
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0079 0.0245 0.0245
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0087 0.0087
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.007 0.007
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.007 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0394 0.0394
Trypanosoma cruzi aldo-keto reductase 0.0031 0.007 0.007
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0013 0.0004 0.0062
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0045 0.0122 0.0122
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0087 0.0087
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.007 0.007
Brugia malayi PHD-finger family protein 0.0025 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0074 0.0226 0.0226
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0394 0.0394
Mycobacterium tuberculosis Conserved hypothetical protein 0.0067 0.0202 0.2578
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0394 0.0394
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0046 0.0126 0.4676
Echinococcus multilocularis microtubule associated protein 2 0.0686 0.2448 0.2448
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0175 0.0595 0.0595
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0131 0.0435 0.0435
Echinococcus multilocularis sentrin specific protease 1 0.0045 0.0122 0.0122
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0091 1
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0394 0.0394
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0059 0.0172 0.0172
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0073 0.0073
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.0076 0.0076
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.006 0.006
Brugia malayi jmjC domain containing protein 0.0059 0.0172 0.0172
Schistosoma mansoni DNA polymerase eta 0.0093 0.0294 0.0294
Trypanosoma cruzi DNA polymerase eta, putative 0.0046 0.0126 0.0126
Schistosoma mansoni patched 1 0.114 0.4092 0.4092
Trichomonas vaginalis aldehyde oxidase, putative 0.0167 0.0565 0.1211
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0397 0.14 0.14
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0167 0.0565 0.1211
Loa Loa (eye worm) hypothetical protein 0.0036 0.0087 0.0087
Echinococcus multilocularis peregrin 0.0088 0.0277 0.0277
Mycobacterium tuberculosis Conserved protein 0.0036 0.0087 0.1115
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0052 0.0112
Brugia malayi Bloom's syndrome protein homolog 0.002 0.003 0.003
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.007 0.007
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.007 0.007
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0091 0.0091
Giardia lamblia Sentrin specific protease, putative 0.0013 0.0004 0.0008
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Trypanosoma cruzi aldo/keto reductase, putative 0.0031 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0175 0.0591 0.0591
Brugia malayi jmjC domain containing protein 0.0059 0.0172 0.0172
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0034 0.0034
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0032 0.0032
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0086 0.0269 0.0269
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0064 0.2385
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0013 0.0004 0.0008
Trichomonas vaginalis rotamase, putative 0.0032 0.0073 0.0157
Loa Loa (eye worm) hypothetical protein 0.0178 0.0604 0.0604
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0091 0.3401
Giardia lamblia DINP protein human, muc B family 0.008 0.0249 0.0534
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0131 0.0435 0.0435
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0064 0.0137
Loa Loa (eye worm) Ulp1 protease 0.0013 0.0004 0.0004
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.2768 1 1
Mycobacterium ulcerans DNA polymerase IV 0.012 0.0394 0.0394
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0172 0.0172
Loa Loa (eye worm) oxidoreductase 0.0031 0.007 0.007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0026 0.0026
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0087 0.1115
Leishmania major DNA damage repair protein, putative 0.0021 0.0034 0.0034
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0077 0.0989
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0045 0.0122 0.2058
Echinococcus multilocularis sentrin specific protease 8 0.0013 0.0004 0.0004
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.013 0.013
Leishmania major DNA polymerase eta, putative 0.0046 0.0126 0.0126
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0013 0.0004 0.0008
Echinococcus multilocularis geminin 0.0332 0.1163 0.1163
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0087 0.0087
Toxoplasma gondii exonuclease III APE 0.0019 0.0026 0.0969
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0091 0.0196
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.035 0.075
Mycobacterium ulcerans DNA polymerase IV 0.012 0.0394 0.0394
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0032 0.0074 0.0074
Brugia malayi jmjC domain containing protein 0.0059 0.0172 0.0172
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.035 0.035
Treponema pallidum hypothetical protein 0.0027 0.0057 0.0952
Brugia malayi N-terminal motif family protein 0.018 0.0609 0.0609
Mycobacterium ulcerans beta-lactamase 0.0036 0.0087 0.0087
Leishmania major DNA polymerase kappa, putative 0.0021 0.0034 0.0034
Schistosoma mansoni DNA helicase recq5 0.002 0.003 0.003
Onchocerca volvulus 0.0031 0.007 0.1152
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.013 0.013
Trichomonas vaginalis esterase, putative 0.0036 0.0087 0.0187
Loa Loa (eye worm) hypothetical protein 0.0054 0.0154 0.0154
Trypanosoma cruzi hypothetical protein 0.0013 0.0004 0.0004
Trypanosoma brucei aldo-keto reductase, putative 0.0031 0.007 0.007
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0087 0.0087
Echinococcus multilocularis aldo keto reductase 0.0031 0.007 0.007
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0091 0.0091
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0076 0.0163
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.035 0.035
Leishmania major hypothetical protein, conserved 0.0015 0.0013 0.0013
Mycobacterium tuberculosis Probable oxidoreductase 0.0031 0.007 0.0896
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0131 0.0435 0.0435
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0249 0.0249
Echinococcus multilocularis tumor protein p63 0.0336 0.1177 0.1177
Entamoeba histolytica hypothetical protein 0.0175 0.0595 1
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0031 0.007 0.007
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0073 0.123
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0131 0.0435 0.7306
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0026 0.0969
Plasmodium vivax JmjC domain containing protein 0.0059 0.0172 0.6383
Echinococcus granulosus sentrin specific protease 7 0.0013 0.0004 0.0004
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0064 0.2385
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0131 0.0435 0.0435
Echinococcus multilocularis sterol regulatory element binding protein 0.114 0.4092 0.4092
Brugia malayi mbt repeat family protein 0.0047 0.013 0.013
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.007 0.007
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0073 0.2721
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0175 0.0595 0.0595
Schistosoma mansoni microtubule-associated protein tau 0.0686 0.2448 0.2448
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.007 0.007
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.0783 1
Trypanosoma cruzi ISWI complex protein 0.0015 0.0013 0.0013
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0064 0.2385
Giardia lamblia Aldose reductase 0.0031 0.007 0.015
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0087 0.1115
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0059 0.0172 0.0172
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0077 0.2212
Brugia malayi Protein kinase domain containing protein 0.0175 0.0595 0.0595
Echinococcus granulosus aldehyde reductase 0.0022 0.0038 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0226 0.0226
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0064 0.0137
Trypanosoma brucei DNA damage repair protein, putative 0.0021 0.0034 0.0034
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0052 0.0052
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0154 0.0154
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0087 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0394 0.0394
Echinococcus granulosus aldo keto reductase 0.0031 0.007 0.007
Toxoplasma gondii aldose reductase, putative 0.0031 0.007 0.261
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0038 0.1078
Entamoeba histolytica protein kinase, putative 0.0175 0.0595 1
Loa Loa (eye worm) oxidoreductase 0.0031 0.007 0.007
Giardia lamblia Aldose reductase 0.0031 0.007 0.015
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.013 0.013
Loa Loa (eye worm) jmjC domain-containing protein 0.0177 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0036 0.0087 0.0087
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.035 0.035
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0087 0.0187
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0045 0.0122 0.0122
Trypanosoma cruzi ISWI complex protein 0.0015 0.0013 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0034 0.0034
Brugia malayi beta-lactamase 0.0036 0.0087 0.0087
Echinococcus granulosus hypothetical protein 0.0031 0.007 0.007
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.013 0.013
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0019 0.0019
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0154 0.0154
Echinococcus multilocularis sentrin specific protease 7 0.0013 0.0004 0.0004
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0064 0.0137
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0087 0.1115
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Schistosoma mansoni aldo-keto reductase 0.0031 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0172
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Onchocerca volvulus 0.0049 0.0137 0.2242
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0059 0.0172 0.6383
Schistosoma mansoni hypothetical protein 0.0332 0.1163 0.1163
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0091 0.0091
Trypanosoma brucei DNA damage repair protein, putative 0.0021 0.0034 0.0034
Onchocerca volvulus 0.0036 0.0087 0.1433
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0013 0.0004 0.0062
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.035 0.5891
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0394 0.0394
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.0292 0.1018 0.1018
Echinococcus multilocularis lysine specific demethylase 5A 0.0221 0.0759 0.0759
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0131 0.0435 0.0435
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0045 0.0122 0.4552
Loa Loa (eye worm) oxidoreductase 0.0031 0.007 0.007
Loa Loa (eye worm) oxidoreductase 0.0031 0.007 0.007
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0073 0.0073
Echinococcus multilocularis jumonji domain containing 1A 0.0059 0.0172 0.0172
Trypanosoma brucei unspecified product 0.0107 0.0346 0.0346
Schistosoma mansoni zinc finger protein 0.0015 0.0013 0.0013
Echinococcus multilocularis aldo keto reductase 0.0031 0.007 0.007
Mycobacterium ulcerans lipase LipD 0.0036 0.0087 0.0087
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0019 0.0019
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0064 0.0137
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0026 0.0026
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0013 0.0004 0.0004
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0031 0.007 0.2004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0087 0.0087
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0019 0.0019
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0057 0.0163 0.2084
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0067 0.0202 0.0202
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0131 0.0435 0.0435
Onchocerca volvulus Alhambra homolog 0.0086 0.0269 0.4412
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.2768 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0174 0.0174
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0175 0.0595 0.0595
Plasmodium vivax hypothetical protein, conserved 0.0086 0.0269 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0096 0.0096
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0191 0.065 0.065
Schistosoma mansoni hypothetical protein 0.002 0.0032 0.0032
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0032 0.0074 0.0947
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.003 0.0064
Trypanosoma cruzi DNA polymerase eta, putative 0.0093 0.0294 0.0294
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0061 0.0179 0.0179
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.1299 0.4669 1
Entamoeba histolytica recQ family helicase, putative 0.002 0.003 0.0499
Loa Loa (eye worm) PHD-finger family protein 0.0086 0.0269 0.0269
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.0076 0.0076
Trypanosoma brucei unspecified product 0.0046 0.0126 0.0126
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.035 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0026 0.0026
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0026 0.0056
Trypanosoma brucei prostaglandin f synthase 0.0031 0.007 0.007
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.003 0.003
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0131 0.0435 0.0435
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0052 0.1939
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.035 0.035
Echinococcus granulosus Protein patched homolog 1 0.114 0.4092 0.4092
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0052 0.0052
Trichomonas vaginalis Sentrin-specific protease, putative 0.0013 0.0004 0.0008
Brugia malayi CHE-14 protein 0.114 0.4092 0.4092
Loa Loa (eye worm) hypothetical protein 0.018 0.0609 0.0609
Echinococcus granulosus geminin 0.0332 0.1163 0.1163
Brugia malayi Flap endonuclease-1 0.0026 0.0052 0.0052
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.035 0.4473
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.008 0.0249 0.0249
Schistosoma mansoni zinc finger protein 0.0019 0.0028 0.0028
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.003 0.003
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0052 0.0112
Loa Loa (eye worm) hypothetical protein 0.002 0.003 0.003
Echinococcus granulosus jumonji domain containing 1A 0.0059 0.0172 0.0172
Echinococcus multilocularis phd:f box containing protein 0.0059 0.0172 0.0172
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.012 0.0394 0.0843
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0137 0.0137
Schistosoma mansoni jumonji/arid domain-containing protein 0.0223 0.0765 0.0765
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0087 0.0087
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.0386 0.0386
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0013 0.0004 0.0004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.0386 0.0386
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0039 0.0039
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0067 0.0067
Brugia malayi jmjC domain containing protein 0.0223 0.0765 0.0765
Echinococcus multilocularis zinc finger protein 0.0019 0.0028 0.0028
Schistosoma mansoni hypothetical protein 0.0015 0.0013 0.0013
Brugia malayi beta-lactamase family protein 0.0036 0.0087 0.0087
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0057 0.0163 0.0163
Trypanosoma brucei DNA polymerase IV, putative 0.012 0.0394 0.0394
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0172 0.0172
Leishmania major DNA polymerase kappa, putative 0.008 0.0249 0.0249
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.2768 1 1
Echinococcus granulosus transcription factor Dp 1 0.0076 0.0234 0.0234
Trypanosoma brucei chrX additional, unordered contigs 0.0021 0.0034 0.0034
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0026 0.0026
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0026 0.0056
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.007 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0174 0.0174
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0394 0.0394
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0397 0.14 0.14
Echinococcus granulosus zinc finger protein 0.0019 0.0028 0.0028
Schistosoma mansoni rotamase 0.0032 0.0076 0.0076
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.005 0.0138 0.0138
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0026 0.0438
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0086 0.0269 0.0269
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0111 0.036 0.036
Treponema pallidum quinoline 2-oxidoreductase 0.0027 0.0055 0.0881
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.007 0.007
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0031 0.007 0.007
Echinococcus granulosus sterol regulatory element binding protein 0.114 0.4092 0.4092
Leishmania major prostaglandin f synthase, putative 0.0031 0.007 0.007
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0172 0.0172
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0059 0.0172 0.0172
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.1299 0.4669 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0118 0.0386 0.0386
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0019 0.0019
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0019 0.0019
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0026 0.2848
Echinococcus multilocularis lysine specific demethylase 6a 0.0059 0.0172 0.0172
Trichomonas vaginalis rotamase, putative 0.0032 0.0076 0.0163
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.007 0.015
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.1299 0.4669 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0059 0.0172 0.6383
Leishmania major DNA polymerase eta, putative 0.0093 0.0294 0.0294
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.007 0.015
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0394 0.0394
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.035 0.035
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0106 0.0344 0.0344
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0045 0.0122 0.0262
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0064 1
Trichomonas vaginalis DNA polymerase eta, putative 0.012 0.0394 0.0843
Echinococcus granulosus jumonji domain containing protein 0.0119 0.0391 0.0391
Schistosoma mansoni aldo-keto reductase 0.0031 0.007 0.007
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0394 0.0394
Plasmodium falciparum DNA repair protein REV1, putative 0.0021 0.0034 0.1258
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0013 0.0006 0.0074
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0026 0.0026
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0064 0.2385
Trypanosoma brucei ISWI complex protein 0.0015 0.0013 0.0013
Onchocerca volvulus 0.0031 0.007 0.1152
Echinococcus granulosus dna polymerase kappa 0.012 0.0394 0.0394
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0118 0.0386 0.4929
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0087 0.0087
Echinococcus granulosus dual specificity 0.0175 0.0595 0.0595
Schistosoma mansoni DNA helicase recq1 0.002 0.003 0.003
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.035 0.035
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0175 0.0595 0.0595
Mycobacterium tuberculosis Conserved protein 0.0036 0.0087 0.1115
Entamoeba histolytica aldose reductase, putative 0.0031 0.007 0.118
Echinococcus multilocularis protein dispatched 1 0.114 0.4092 0.4092
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.2768 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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