Detailed information for compound 994589

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 298.247 | Formula: C16H10O6
  • H donors: 2 H acceptors: 5 LogP: 2.56 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1cc(O)c2c(c1)C(=O)c1c(C2=O)c(O)ccc1
  • InChi: 1S/C16H10O6/c1-22-16(21)7-5-9-13(11(18)6-7)15(20)12-8(14(9)19)3-2-4-10(12)17/h2-6,17-18H,1H3
  • InChiKey: SGDMEGYCHABPCQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens purinergic receptor P2Y, G-protein coupled, 12 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans putative regulatory protein 0.0036 0.011 0.1913
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0321 0.1945 0.2751
Mycobacterium tuberculosis Conserved protein 0.0024 0.0037 0.0563
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.018 0.0253
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0608 0.3788 1
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0167 0.0748
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0026 0.0183
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.1204 0.1476
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0608 0.3788 0.4644
Loa Loa (eye worm) hypothetical protein 0.0076 0.0369 0.0451
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0167 0.0752
Brugia malayi Bromodomain containing protein 0.0031 0.0082 0.0081
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0094 0.2527
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0301 0.03
Mycobacterium tuberculosis Probable reductase 0.0107 0.0567 0.8809
Leishmania major hypothetical protein, conserved 0.021 0.1234 0.555
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0608 0.3788 0.4644
Schistosoma mansoni hypothetical protein 0.0034 0.0098 0.0137
Brugia malayi nuclear receptor RXR 0.0287 0.1724 0.1724
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0023 0.0026 0.0025
Onchocerca volvulus 0.0027 0.0053 0.0115
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0004 0.0023
Brugia malayi tailless protein 0.0287 0.1724 0.1724
Echinococcus granulosus chromobox protein 1 0.008 0.0397 0.0897
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0003 0.0005
Onchocerca volvulus 0.0058 0.0257 0.0656
Brugia malayi hypothetical protein 0.0161 0.0919 0.0918
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0003 0.0003
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0205 0.0289
Echinococcus multilocularis zinc finger protein 0.0019 0.0006 0.0007
Echinococcus granulosus RUN 0.0058 0.0257 0.0581
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0037 0.0261
Schistosoma mansoni chromobox protein 0.008 0.0397 0.056
Entamoeba histolytica hypothetical protein 0.0019 0.0003 0.004
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0205 0.1474
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0287 0.1724 0.2439
Brugia malayi Nuclear hormone receptor-like 1 0.1287 0.8157 0.8157
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0572 0.0701
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.005 0.0357
Echinococcus granulosus chromobox protein 1 0.008 0.0397 0.0897
Loa Loa (eye worm) hypothetical protein 0.005 0.0202 0.0247
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0116 0.0833
Plasmodium vivax multidomain scavenger receptor, putative 0.0058 0.0257 0.6975
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0183
Plasmodium falciparum heterochromatin protein 1 0.0023 0.0026 0.0691
Loa Loa (eye worm) hypothetical protein 0.0321 0.1945 0.2384
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0017
Echinococcus granulosus thyroid hormone receptor alpha 0.0287 0.1724 0.3904
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0116 0.0833
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0094 0.067
Loa Loa (eye worm) steroid hormone receptor 0.0608 0.3788 0.4644
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0198 0.0197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0183
Echinococcus multilocularis chromobox protein 1 0.008 0.0397 0.056
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0116 0.0163
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0004 0.0023
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0003 0.0003
Echinococcus multilocularis tumor protein p63 0.0334 0.2029 0.287
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0004 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0183
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0004 0.0055
Brugia malayi nuclear receptor NHR-88 0.0287 0.1724 0.1724
Onchocerca volvulus 0.0036 0.011 0.0267
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0608 0.3788 0.3788
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0004 0.0018
Brugia malayi ecdysone receptor 0.0287 0.1724 0.1724
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.011 0.0247
Echinococcus granulosus ecdysone induced protein 78C 0.0608 0.3788 0.858
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0004 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0608 0.3788 0.3788
Brugia malayi PHD-finger family protein 0.0029 0.0067 0.0066
Brugia malayi nuclear receptor NHR-67 0.0287 0.1724 0.1724
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0094 0.067
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0004 0.0014
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0644 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0608 0.3788 0.858
Echinococcus multilocularis thyroid hormone receptor alpha 0.1118 0.7068 1
Schistosoma mansoni RAR-like nuclear receptor 0.0608 0.3788 0.5359
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0004 0.0018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0608 0.3788 0.5359
Brugia malayi hypoxia-induced factor 1 0.0149 0.0838 0.0838
Echinococcus granulosus lamin dm0 0.0027 0.0053 0.0118
Echinococcus multilocularis RUN 0.0058 0.0257 0.0363
Brugia malayi Pre-SET motif family protein 0.0206 0.1204 0.1204
Loa Loa (eye worm) hypothetical protein 0.0038 0.0125 0.0152
Onchocerca volvulus 0.003 0.0076 0.0176
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.1385 0.1958
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0073 0.052
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0003 0.0003
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0226 0.1333 0.1885
Brugia malayi Nuclear hormone receptor-like 1 0.1287 0.8157 0.8157
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0205 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0071 0.191
Brugia malayi Bromodomain containing protein 0.0038 0.0125 0.0124
Schistosoma mansoni chromobox protein 0.0023 0.0026 0.0036
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0364 0.2222 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0036 0.025
Leishmania major cytochrome p450-like protein 0.0026 0.005 0.0219
Loa Loa (eye worm) hypothetical protein 0.0037 0.0116 0.0142
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0572 0.2573
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0003 0.0003
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0287 0.1724 0.2439
Echinococcus granulosus neuropeptide s receptor 0.047 0.29 0.6568
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0608 0.3788 0.858
Echinococcus multilocularis neuropeptide s receptor 0.047 0.29 0.4102
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0301 0.0425
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0116 0.0831
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0205 0.0289
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0205 0.1474
Loa Loa (eye worm) glutathione reductase 0.0047 0.0182 0.0222
Echinococcus multilocularis Chromo domain 0.0023 0.0026 0.0036
Echinococcus multilocularis Chromobox protein 3 0.0023 0.0026 0.0036
Schistosoma mansoni nuclear receptor nhr-48 0.0287 0.1724 0.2439
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0067 0.1789
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0364 0.0513
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0035 0.0249
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0116 0.0519
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0301 0.1351
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0364 0.2222 0.2221
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0608 0.3788 0.5359
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0608 0.3788 0.4644
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0167 0.1198
Echinococcus multilocularis neuropeptide receptor A26 0.047 0.29 0.4102
Giardia lamblia DINP protein human, muc B family 0.0019 0.0004 0.0153
Brugia malayi Bromodomain containing protein 0.0074 0.0358 0.0357
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0003 0.0003
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0003 0.0005
Brugia malayi 6-phosphofructokinase 0.0107 0.0572 0.0571
Onchocerca volvulus 0.0052 0.0216 0.0547
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0384 0.2351 0.3325
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0026 0.0691
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0089 0.0453 0.0639
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0116 0.0519
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0116 0.0831
Loa Loa (eye worm) hypothetical protein 0.0364 0.2222 0.2723
Schistosoma mansoni rab6-interacting 0.0058 0.0257 0.0363
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0067 0.0093
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0116 0.0831
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0567 0.8809
Entamoeba histolytica hypothetical protein 0.0019 0.0003 0.004
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0067 0.0081
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0023 0.0026 0.0058
Onchocerca volvulus 0.0111 0.0598 0.1557
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0287 0.1724 0.4538
Loa Loa (eye worm) hypothetical protein 0.0438 0.2697 0.3306
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0025 0.0034
Echinococcus multilocularis lamin 0.0027 0.0053 0.0073
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0167 0.2907
Loa Loa (eye worm) hypothetical protein 0.0571 0.3553 0.4355
Onchocerca volvulus 0.0608 0.3788 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0205 0.092
Onchocerca volvulus Alhambra homolog 0.0029 0.0067 0.0151
Loa Loa (eye worm) doublecortin family protein 0.0058 0.0257 0.0314
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0106 0.0148
Brugia malayi nuclear hormone receptor 0.0608 0.3788 0.3788
Brugia malayi nuclear receptor RXR 0.0321 0.1945 0.1945
Echinococcus granulosus Nuclear hormone receptor HR96 0.0287 0.1724 0.3904
Loa Loa (eye worm) helicase 0.0023 0.0026 0.0031
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.018 0.0253
Echinococcus multilocularis peregrin 0.0031 0.0082 0.0114
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0264 0.0323
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0116 0.3134
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0116 0.0519
Echinococcus granulosus expressed protein 0.0369 0.2254 0.5105
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.0572 0.1295
Schistosoma mansoni thyroid hormone receptor 0.1118 0.7068 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0116 0.2017
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0301 0.068
Echinococcus multilocularis chromobox protein 2 0.0023 0.0026 0.0036
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0004 0.0007
Entamoeba histolytica hypothetical protein 0.0023 0.0026 0.0445
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0608 0.3788 0.4644
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0257 0.0581
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0287 0.1724 0.2113
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0026 0.0183
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.0572 0.2573
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0042 0.1106
Entamoeba histolytica hypothetical protein 0.0023 0.0026 0.0445
Echinococcus granulosus neuropeptide receptor A26 0.047 0.29 0.6568
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0205 0.5558
Echinococcus granulosus geminin 0.0168 0.0959 0.217
Schistosoma mansoni lamin 0.0027 0.0053 0.0073
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0608 0.3788 0.5359
Schistosoma mansoni intermediate filament proteins 0.0027 0.0053 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0167 0.1198
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0037 0.0563
Brugia malayi 6-phosphofructokinase 0.0107 0.0572 0.0571
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0608 0.3788 0.5359
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0004 0.0018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0183
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0196 0.0276
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0003 0.0003
Schistosoma mansoni zinc finger protein 0.0287 0.1724 0.2439
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0608 0.3788 0.4644
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0349 0.079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0109 0.0777
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.0572 0.8892
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0567 0.8793
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0036 0.025
Loa Loa (eye worm) hypothetical protein 0.0112 0.0598 0.0733
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0004 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0287 0.1724 0.2439
Brugia malayi conserved hypotetical protein 0.0287 0.1724 0.1724
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0068 0.1826
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0183
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0572 0.0809
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0037 0.0163
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0608 0.3788 0.858
Onchocerca volvulus 0.0027 0.0053 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0167 0.1198
Echinococcus multilocularis chromobox protein 1 0.008 0.0397 0.056
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0109 0.0777
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0067 0.0475
Loa Loa (eye worm) hypothetical protein 0.0049 0.0199 0.0243
Brugia malayi hypothetical protein 0.0438 0.2697 0.2696
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0068 0.1175
Schistosoma mansoni nuclear hormone receptor 0.0608 0.3788 0.5359
Brugia malayi hypothetical protein 0.0058 0.0257 0.0256
Plasmodium falciparum thioredoxin reductase 0.0047 0.0182 0.4923
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0004 0.0004
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0109 0.049
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0205 0.092
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0003 0.0003
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0167 0.0204
Schistosoma mansoni DNA polymerase eta 0.0019 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.005 0.0357
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113
Toxoplasma gondii thioredoxin reductase 0.0047 0.0182 0.4923
Onchocerca volvulus 0.0048 0.0188 0.0472
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0068 0.0484
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0608 0.3788 0.3788
Trichomonas vaginalis chromobox protein, putative 0.0053 0.0221 0.1587
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0037 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0572 0.4122
Loa Loa (eye worm) hypothetical protein 0.0186 0.1078 0.132
Loa Loa (eye worm) hypothetical protein 0.0608 0.3788 0.4644
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0017
Echinococcus granulosus chromobox protein 2 0.0023 0.0026 0.0058
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0092 0.141
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0068 0.0484
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0004 0.0004
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0205 0.0251
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.005 0.0851
Loa Loa (eye worm) hypothetical protein 0.007 0.0331 0.0405
Mycobacterium ulcerans endonuclease IV 0.0076 0.0369 0.6435
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0003 0.0002
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0182 0.2817
Leishmania major hypothetical protein, conserved 0.0025 0.0042 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0057 0.0406
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0202 0.1451
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0453 0.0639
Schistosoma mansoni hypothetical protein 0.002 0.0013 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0183
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.0369 0.0368
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0183
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0116 0.2022
Onchocerca volvulus 0.0438 0.2697 0.7112
Brugia malayi PXA domain containing protein 0.0019 0.0003 0.0002
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0191 0.0268
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0004 0.0018
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0003 0.0002
Schistosoma mansoni lozenge 0.0055 0.0235 0.0331
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0026 0.0691
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0004 0.0049
Onchocerca volvulus 0.0234 0.1388 0.3648
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0608 0.3788 0.4644
Brugia malayi hypothetical protein 0.0025 0.0042 0.0041
Loa Loa (eye worm) inositol-1 0.0037 0.0116 0.0141
Loa Loa (eye worm) hypothetical protein 0.0608 0.3788 0.4644
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0445
Trichomonas vaginalis chromobox protein, putative 0.008 0.0397 0.2855
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0287 0.1724 0.4538
Onchocerca volvulus Protein ultraspiracle homolog 0.0608 0.3788 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0183
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0068 0.1826
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0118 0.0265
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0026 0.0691
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0321 0.1945 0.2751
Brugia malayi PAS domain containing protein 0.0048 0.0191 0.019
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0116 0.0833
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0608 0.3788 0.858
Schistosoma mansoni lamin 0.0027 0.0053 0.0073
Loa Loa (eye worm) hypothetical protein 0.0608 0.3788 0.4644
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0572 0.2576
Brugia malayi hypothetical protein 0.0036 0.011 0.0109
Brugia malayi Nuclear hormone receptor E75 0.0287 0.1724 0.1724
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0183
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0006 0.0007
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0572 1
Entamoeba histolytica hypothetical protein 0.0036 0.011 0.191
Brugia malayi Protein cec-1. 0.0023 0.0026 0.0025
Schistosoma mansoni loxhd1 0.0058 0.0257 0.0363
Schistosoma mansoni lipoxygenase 0.0121 0.0656 0.0927
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0003 0.0003
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0116 0.0523
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0023 0.0026 0.0691
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0003 0.0003
Echinococcus multilocularis Polycystic kidney disease protein 0.0058 0.0257 0.0363
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0003 0.0005
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0167 0.0235
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.005
Trypanosoma brucei trypanothione reductase 0.0047 0.0182 0.0819
Onchocerca volvulus Bile acid receptor homolog 0.0608 0.3788 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0705 0.4415 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.005 0.006
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0116 0.052
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0003 0.0005
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0004 0.0004
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0068 0.0484
Schistosoma mansoni nuclear receptor 0.0287 0.1724 0.2439
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0118 0.0165
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.051 0.3161 0.4472
Schistosoma mansoni polycystin 1-related 0.0058 0.0257 0.0363
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0068 0.0484
Echinococcus granulosus FTZ F1 alpha 0.0608 0.3788 0.858
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0031
Schistosoma mansoni lipoxygenase 0.0226 0.1333 0.1885
Loa Loa (eye worm) CHromoDomain protein family member 0.0024 0.0038 0.0046
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.0572 0.8877
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0445
Schistosoma mansoni nuclear hormone receptor 0.0287 0.1724 0.2439
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0321 0.1945 0.4405
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0042 0.0183
Brugia malayi phosphofructokinase 0.0107 0.0572 0.0571
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0009 0.015
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0116 0.0262
Loa Loa (eye worm) hypothetical protein 0.0058 0.0257 0.0314
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0438 0.2697 0.3306
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0183
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0037 0.0633
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0608 0.3788 0.5359
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0167 0.0748
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0608 0.3788 0.3788
Schistosoma mansoni hypothetical protein 0.051 0.3161 0.4472
Schistosoma mansoni hypothetical protein 0.0048 0.0188 0.0265
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0183
Loa Loa (eye worm) hypothetical protein 0.0608 0.3788 0.4644
Plasmodium falciparum glutathione reductase 0.0047 0.0182 0.4923
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0116 0.0262
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0004 0.0018
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0116 0.0524
Echinococcus multilocularis musashi 0.0027 0.0053 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0109 0.0777
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0182 0.4923
Echinococcus granulosus intermediate filament protein 0.0027 0.0053 0.0118
Schistosoma mansoni chromobox protein 0.0023 0.0026 0.0036
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0124 0.0279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0094 0.067
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0567 0.8809
Echinococcus multilocularis expressed protein 0.0369 0.2254 0.3189
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.1287 0.8157 1
Brugia malayi M-phase phosphoprotein, mpp8 0.0111 0.0598 0.0597
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0003 0.0005
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0004 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0287 0.1724 0.3904
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0608 0.3788 0.5359
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0013 0.0014
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0064 0.0143
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0116 0.5653
Brugia malayi Doublecortin family protein 0.0058 0.0257 0.0256
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0608 0.3788 0.5359
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0004 0.0049
Schistosoma mansoni survival motor neuron protein 0.0048 0.0188 0.0265
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0067 0.1789
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0124 0.0175
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0004 0.0055
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0042 0.0187
Trypanosoma brucei unspecified product 0.0019 0.0004 0.0018
Brugia malayi Cytochrome P450 family protein 0.0026 0.005 0.0049
Mycobacterium ulcerans hypothetical protein 0.0024 0.0037 0.0633
Trichomonas vaginalis chromobox protein, putative 0.0053 0.0221 0.1587
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0567 0.8809
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0116 0.052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0016 0.0074
Brugia malayi Inositol-1 0.0037 0.0116 0.0115
Echinococcus multilocularis lamin dm0 0.0027 0.0053 0.0073
Echinococcus granulosus zinc finger protein 0.0019 0.0006 0.0011
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0006 0.0012
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.011 0.0154
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0236 0.0289
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.1385 0.3135
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0068 0.1175
Brugia malayi hypothetical protein 0.0019 0.0003 0.0002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.011 0.0154
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0369 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0608 0.3788 0.3788
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0257 0.0363
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0017
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0003 0.0002
Brugia malayi intermediate filament protein 0.0027 0.0053 0.0052
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0068 0.1826
Entamoeba histolytica hypothetical protein 0.0036 0.011 0.191
Schistosoma mansoni hypothetical protein 0.0168 0.0959 0.1355
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0052 0.0216 0.0305
Plasmodium falciparum phd finger protein, putative 0.0029 0.0067 0.1789
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0076 0.0092
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.011 0.0154
Loa Loa (eye worm) hypothetical protein 0.0321 0.1945 0.2384
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0287 0.1724 0.1724
Entamoeba histolytica hypothetical protein 0.0036 0.011 0.191
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0006 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0608 0.3788 0.3788
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0026 0.0183
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0042 0.1106
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.0369 0.5722
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0003 0.0005
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.018 0.0405
Echinococcus granulosus jumonji domain containing protein 0.004 0.0139 0.0313
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0116 0.2017
Schistosoma mansoni hypothetical protein 0.0036 0.011 0.0154
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0037 0.0082
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0092 0.1294
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0644 1
Brugia malayi nuclear receptor NHR-88 0.0608 0.3788 0.3788
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0026 0.0036
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0025 0.0054
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0003 0.0003
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0068 0.1826
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0004 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0052 0.0369
Brugia malayi Cytochrome P450 family protein 0.0026 0.005 0.0049
Brugia malayi Nuclear hormone receptor E75 0.0287 0.1724 0.1724
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0017
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0257 0.0581
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.0572 0.0809
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus granulosus Chromo domain 0.0023 0.0026 0.0058
Entamoeba histolytica hypothetical protein 0.0036 0.011 0.191
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0257 0.0363
Schistosoma mansoni inositol monophosphatase 0.0037 0.0116 0.0163
Brugia malayi nuclear hormone receptor family member nhr-6 0.0287 0.1724 0.1724
Trypanosoma brucei C-8 sterol isomerase, putative 0.0364 0.2222 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0205 0.092
Brugia malayi hypothetical protein 0.0019 0.0003 0.0002
Echinococcus multilocularis dna polymerase eta 0.0019 0.0004 0.0004
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0349 0.0493
Echinococcus multilocularis nuclear receptor nhr 48 0.0287 0.1724 0.2439
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0006 0.0006
Brugia malayi hypothetical protein 0.0112 0.0598 0.0598
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0445
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0037 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0608 0.3788 0.3788
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0003 0.0003
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0116 0.052
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0572 0.4122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0125 0.0897
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0572 0.4122
Loa Loa (eye worm) phosphofructokinase 0.0107 0.0572 0.0701
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0004 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0035 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0202 0.1451
Loa Loa (eye worm) hypothetical protein 0.004 0.014 0.0171
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0205 0.0289
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0287 0.1724 0.2439
Trypanosoma cruzi hypothetical protein, conserved 0.021 0.1234 0.555
Loa Loa (eye worm) hypoxia-induced factor 1 0.0149 0.0838 0.1027
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.018 0.0253
Trypanosoma cruzi hypothetical protein, conserved 0.021 0.1234 0.555
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0608 0.3788 0.5359
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0003 0.0003
Brugia malayi hypothetical protein 0.0287 0.1724 0.1724
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.011 0.0247
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0003 0.0003
Brugia malayi bHLH-PAS transcription factor 0.0036 0.011 0.0109
Brugia malayi chromobox protein homolog 3 0.005 0.0202 0.0201
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.051 0.3161 0.7159
Schistosoma mansoni single-minded 0.0048 0.0191 0.0268
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0261 0.0368
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0608 0.3788 0.3788
Schistosoma mansoni nuclear receptor 0.0287 0.1724 0.2439
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0608 0.3788 0.4644
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0089 0.0453 0.1023
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0321 0.1945 0.2751
Echinococcus multilocularis Protein lozenge 0.0055 0.0235 0.0331
Brugia malayi PXA domain containing protein 0.0019 0.0003 0.0002
Brugia malayi steroid hormone receptor 0.0608 0.3788 0.3788
Loa Loa (eye worm) hypothetical protein 0.0049 0.0198 0.0242
Echinococcus granulosus nuclear receptor nhr 48 0.0287 0.1724 0.3904
Trichomonas vaginalis Heterochromatin protein, putative 0.0023 0.0026 0.0183
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0037 0.0633
Echinococcus granulosus Nuclear hormone receptor HR96 0.0287 0.1724 0.3904
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0261 0.0589
Schistosoma mansoni rab6-interacting 0.0058 0.0257 0.0363
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0003 0.0005
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0608 0.3788 0.5359
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0004 0.0018
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0109 0.0486
Loa Loa (eye worm) hypothetical protein 0.0608 0.3788 0.4644
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0004 0.0055
Loa Loa (eye worm) hypothetical protein 0.0042 0.0152 0.0186
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0067 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0183
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0026 0.0036
Loa Loa (eye worm) hypothetical protein 0.0029 0.0067 0.0081
Brugia malayi CHD4 protein 0.0024 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.1253 0.7936 0.9729
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0167 0.2907
Echinococcus granulosus lamin 0.0027 0.0053 0.0118
Echinococcus granulosus dna polymerase kappa 0.0019 0.0004 0.0007
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0026 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0608 0.3788 0.3788
Schistosoma mansoni nuclear hormone receptor 0.0287 0.1724 0.2439
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0608 0.3788 0.3788
Loa Loa (eye worm) heterochromatin protein 1 0.008 0.0397 0.0485
Loa Loa (eye worm) hypothetical protein 0.0046 0.018 0.0219
Chlamydia trachomatis endonuclease IV 0.0076 0.0369 1
Entamoeba histolytica hypothetical protein 0.0019 0.0003 0.004
Schistosoma mansoni inositol monophosphatase 0.0037 0.0116 0.0163
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0071 0.0099
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0118 0.0165
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0068 0.0484
Loa Loa (eye worm) hypothetical protein 0.0321 0.1945 0.2384
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0183
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0205 0.092
Brugia malayi nuclear hormone receptor family member odr-7 0.0287 0.1724 0.1724
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0004 0.0018
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0068 0.1826
Trypanosoma brucei hypothetical protein, conserved 0.021 0.1234 0.5552
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0226 0.1333 0.3018
Echinococcus granulosus single minded 2 0.0036 0.011 0.0248
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0004 0.0018
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0098 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0183
Loa Loa (eye worm) nuclear hormone receptor 0.0287 0.1724 0.2113
Giardia lamblia GTOR 0.0044 0.0167 0.8129
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0025 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0094 0.067
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0369 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0031
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0003 0.0002
Echinococcus multilocularis geminin 0.0168 0.0959 0.1355
Echinococcus granulosus Chromobox protein 3 0.0023 0.0026 0.0058
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0009 0.0134
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0183
Onchocerca volvulus 0.0287 0.1724 0.4538
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0167 0.0752
Schistosoma mansoni chromobox protein 0.008 0.0397 0.056
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0068 0.3285
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0053 0.0064
Brugia malayi PHD-finger family protein 0.0025 0.004 0.0039
Brugia malayi hypothetical protein 0.0234 0.1385 0.1384
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0139 0.0196
Echinococcus granulosus peregrin 0.0031 0.0082 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0608 0.3788 0.3788
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0167 0.0748
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0053 0.0052
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0067 0.1789
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0094 0.067
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.005 0.0219
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0071 0.0099
Schistosoma mansoni steroid hormone receptor ad4bp 0.0608 0.3788 0.5359
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0205 0.0463
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0116 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0067 0.0093
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0003 0.0003
Brugia malayi Heterochromatin protein 1 0.008 0.0397 0.0396
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0004 0.0014
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0003 0.0002
Schistosoma mansoni retinoic acid receptor RXR 0.0705 0.4415 0.6246
Schistosoma mansoni coup transcription factor 0.0608 0.3788 0.5359
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0116 0.0163
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0188 0.0187
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0301 0.0425
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0234 0.1385 0.1697
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0068 0.0484
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0068 0.1826
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0198 0.0242
Mycobacterium ulcerans hypothetical protein 0.0024 0.0037 0.0633
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0004 0.0018
Echinococcus multilocularis FTZ F1 alpha 0.0608 0.3788 0.5359
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0004 0.0018
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0024 0.0038 0.0053
Leishmania major trypanothione reductase 0.0047 0.0182 0.0815
Trichomonas vaginalis hypothetical protein 0.0023 0.0026 0.0183
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0205 0.0463
Schistosoma mansoni zinc finger protein 0.0019 0.0006 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0036 0.025
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0488 0.1104
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0167 0.0748
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0182 0.041
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0116 0.0163
Brugia malayi orphan nuclear receptor NR2E1 0.0287 0.1724 0.1724
Entamoeba histolytica hypothetical protein 0.0023 0.0026 0.0445
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0488 0.069
Loa Loa (eye worm) hypothetical protein 0.0321 0.1945 0.2384
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0004 0.0018
Echinococcus granulosus Polycystic kidney disease protein 0.0058 0.0257 0.0581
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0205 0.1474
Brugia malayi MAP kinase sur-1 0.005 0.0205 0.0204
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0116 0.0116
Brugia malayi nuclear hormone receptor 0.0287 0.1724 0.1724
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0572 0.4122
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0608 0.3788 0.5359
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0031
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0572 1
Leishmania major DNA polymerase eta, putative 0.0019 0.0004 0.0014
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0004 0.0004
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0287 0.1724 0.3904
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0036 0.025
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0004 0.0003
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0024 0.0038 0.0085
Trypanosoma brucei protein kinase, putative 0.005 0.0205 0.0924
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113
Plasmodium vivax heterochromatin protein 1, putative 0.0023 0.0026 0.0691
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0301 0.5251
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0052 0.0369
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0109 0.0777
Trichomonas vaginalis set domain proteins, putative 0.0234 0.1387 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0301 0.1351
Loa Loa (eye worm) hypothetical protein 0.0049 0.0196 0.0239
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0023 0.0026 0.0691
Brugia malayi ecdysteroid receptor 0.0608 0.3788 0.3788
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0644 1
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0026 0.0691
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0644 1
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0003 0.0003
Brugia malayi hypothetical protein 0.0321 0.1945 0.1945
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.005 0.0219
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0182 0.0256
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0116 0.0163
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0608 0.3788 0.858
Onchocerca volvulus 0.0111 0.0598 0.1557
Brugia malayi glutathione reductase 0.0047 0.0182 0.0181
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0608 0.3788 0.5359
Mycobacterium ulcerans hypothetical protein 0.002 0.0009 0.015
Trypanosoma brucei cytochrome P450, putative 0.0026 0.005 0.0223
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.0572 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0057 0.0406
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0183
Onchocerca volvulus 0.0058 0.0257 0.0656
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0053 0.0064
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0037 0.0633
Loa Loa (eye worm) hypothetical protein 0.0058 0.0257 0.0314
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0023 0.0026 0.0036
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.006
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0042 0.0183
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0003 0.0003
Plasmodium falciparum LCCL domain-containing protein 0.0058 0.0257 0.6975
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0183
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0001 0.0004
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0003 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0182 0.0815
Brugia malayi photoreceptor-specific nuclear receptor 0.0608 0.3788 0.3788
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.005 0.006
Brugia malayi Cytochrome P450 family protein 0.0055 0.0236 0.0236
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0567 0.8809
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0167 0.0376
Onchocerca volvulus 0.0287 0.1724 0.4538
Loa Loa (eye worm) hypothetical protein 0.0111 0.0598 0.0732
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0026 0.0691
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0608 0.3788 0.3788
Schistosoma mansoni thyroid hormone receptor 0.1118 0.7068 1
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0068 0.1826
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0037 0.0163
Plasmodium vivax SET domain protein, putative 0.003 0.0071 0.191
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0287 0.1724 0.2439
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0608 0.3788 0.858
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0301 0.1354
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0004 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0068 0.0484
Loa Loa (eye worm) hypothetical protein 0.0034 0.0098 0.0119
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0003 0.0005
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0205 0.0924
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0802 0.5036 0.7125
Onchocerca volvulus 0.0049 0.0196 0.0493
Loa Loa (eye worm) hypothetical protein 0.0027 0.0053 0.0064
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0031
Leishmania major C-8 sterol isomerase-like protein 0.0364 0.2222 1
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0205 0.1474
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0287 0.1724 0.2439
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113
Leishmania major DNA polymerase kappa, putative 0.0019 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0116 0.0262
Schistosoma mansoni hypothetical protein 0.0168 0.0959 0.1355
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0053 0.0221 0.056
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0006 0.0005
Trichomonas vaginalis chromobox protein, putative 0.008 0.0397 0.2855
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0572 1
Brugia malayi small heat shock protein 0.0571 0.3553 0.3553
Echinococcus granulosus tumor protein p63 0.0334 0.2029 0.4595
Plasmodium vivax glutathione reductase, putative 0.0047 0.0182 0.4923
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0608 0.3788 0.4644
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.0572 1
Loa Loa (eye worm) hypothetical protein 0.0608 0.3788 0.4644
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0183
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0301 0.1351
Schistosoma mansoni bromodomain containing protein 0.0063 0.0284 0.04
Echinococcus granulosus dna polymerase eta 0.0019 0.0004 0.0007
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0116 0.0163
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0116 0.0163
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0608 0.3788 0.5359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0052 0.0369
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0094 0.067
Giardia lamblia PHD finger protein 15 0.0029 0.0067 0.3219
Brugia malayi hypothetical protein 0.0287 0.1724 0.1724
Brugia malayi Valyl-tRNA synthetase 0.0023 0.0026 0.0025
Brugia malayi hypothetical protein 0.0321 0.1945 0.1945
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0205 0.092
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0003 0.0017
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0167 0.0166
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0042 0.1106
Brugia malayi Thioredoxin reductase 0.0047 0.0182 0.0181
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0038 0.0053
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0116 0.0261
Toxoplasma gondii endonuclease IV APN 0.0076 0.0369 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0118 0.0143
Loa Loa (eye worm) DR-78 0.0287 0.1724 0.2113
Brugia malayi Pre-SET motif family protein 0.003 0.0071 0.007
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0572 0.0701
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0161 0.0919 0.1125
Loa Loa (eye worm) CYP4Cod1 0.0026 0.005 0.006
Loa Loa (eye worm) runx1 0.0055 0.0235 0.0286
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0453 0.0639
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0109 0.0777
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0182 0.0222
Brugia malayi SET domain containing protein 0.0024 0.0033 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0608 0.3788 0.3788
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0567 0.8809
Loa Loa (eye worm) nuclear receptor NHR-67 0.0287 0.1724 0.2113
Brugia malayi jmjC domain containing protein 0.0037 0.0118 0.0117
Brugia malayi Steroid receptor seven-up type 2 0.0608 0.3788 0.3788
Brugia malayi Associated with TFs and helicases family protein 0.0023 0.0026 0.0025
Schistosoma mansoni hypothetical protein 0.0058 0.0257 0.0363
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0042 0.1106
Schistosoma mansoni hypothetical protein 0.0023 0.0026 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0094 0.067
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.011 0.0155
Loa Loa (eye worm) hypothetical protein 0.0321 0.1945 0.2384
Brugia malayi hypothetical protein 0.0058 0.0257 0.0256
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0035 0.0249
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0608 0.3788 0.4644
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0109 0.0486
Mycobacterium ulcerans epimerase 0.002 0.0009 0.015
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0205 0.092
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0183
Brugia malayi jmjC domain containing protein 0.0094 0.0488 0.0488
Schistosoma mansoni hypothetical protein 0.0029 0.0067 0.0093
Echinococcus multilocularis ecdysone induced protein 78C 0.0608 0.3788 0.5359
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0167 0.0235
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0198 0.0197
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0003 0.0003
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0572 0.0809
Onchocerca volvulus Heterochromatin protein 1 homolog 0.005 0.0202 0.051
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.0369 0.5664
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0301 0.0368
Loa Loa (eye worm) hypothetical protein 0.0287 0.1724 0.2113

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 2 % Displacement of [3H]PSB0413 from human platelet P2Y12 receptor at 10 uM ChEMBL. 19463000
Ki (binding) > 10 uM Displacement of [3H]PSB0413 from human platelet P2Y12 receptor ChEMBL. 19463000

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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