Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0367 | 0.0721 | 0.5074 |
Mycobacterium leprae | Probable integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase) | 0.4557 | 1 | 1 |
Mycobacterium ulcerans | two component sensory transduction histidine kinase MtrB | 0.0085 | 0.0098 | 0.0046 |
Trypanosoma brucei | heat shock protein, putative | 0.0191 | 0.0332 | 0.1346 |
Chlamydia trachomatis | DNA gyrase subunit A | 0.0098 | 0.0126 | 0.0088 |
Mycobacterium tuberculosis | Probable two component sensor kinase | 0.0085 | 0.0098 | 0.0046 |
Leishmania major | mitochondrial DNA topoisomerase II | 0.1155 | 0.2466 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0048 | 0.0196 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0207 | 0.0367 | 0.0867 |
Brugia malayi | glutaminase DH11.1 | 0.0271 | 0.0508 | 0.3515 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0463 | 0.0933 | 0.6636 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0106 | 0.0143 | 0.0046 |
Trichomonas vaginalis | endoplasmin, putative | 0.014 | 0.0218 | 0.1388 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0115 | 0.0163 | 0.0735 |
Mycobacterium tuberculosis | Conserved protein | 0.0085 | 0.0098 | 0.0046 |
Plasmodium vivax | SET domain protein, putative | 0.0066 | 0.0055 | 0.0079 |
Entamoeba histolytica | DNA topoisomerase III, putative | 0.0115 | 0.0163 | 0.0984 |
Treponema pallidum | chemotaxis histidine kinase (cheA) | 0.0085 | 0.0098 | 0.0139 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DosT | 0.0085 | 0.0098 | 0.0046 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0048 | 0.0196 |
Mycobacterium ulcerans | sensor kinase from two component regulatory system | 0.0085 | 0.0098 | 0.0046 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.067 | 0.1392 | 0.4095 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.058 | 0.1193 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0226 | 0.0409 | 0.2791 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0048 | 0.0196 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0048 | 0.0196 |
Schistosoma mansoni | ap endonuclease | 0.0065 | 0.0051 | 0.0165 |
Echinococcus multilocularis | heat shock protein | 0.0191 | 0.0332 | 0.0778 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0967 | 0.2049 | 1 |
Loa Loa (eye worm) | endoplasmin | 0.0191 | 0.0332 | 0.2222 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.1557 | 0.3357 | 1 |
Echinococcus multilocularis | endoplasmin | 0.0106 | 0.0143 | 0.0292 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0065 | 0.0261 |
Onchocerca volvulus | 0.0066 | 0.0055 | 0.0227 | |
Trichomonas vaginalis | set domain proteins, putative | 0.0527 | 0.1075 | 0.7675 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.1557 | 0.3357 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0207 | 0.0367 | 0.2477 |
Plasmodium vivax | heat shock protein 86, putative | 0.0191 | 0.0332 | 0.091 |
Trichomonas vaginalis | glutaminase, putative | 0.0271 | 0.0508 | 0.3515 |
Onchocerca volvulus | 0.0527 | 0.1075 | 0.8985 | |
Mycobacterium tuberculosis | Possible two component sensor kinase | 0.0085 | 0.0098 | 0.0046 |
Wolbachia endosymbiont of Brugia malayi | signal transduction histidine kinase and receiver | 0.0085 | 0.0098 | 0.0139 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0085 | 0.0098 | 0.0176 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0048 | 0.0079 |
Schistosoma mansoni | prokaryotic DNA topoisomerase | 0.0115 | 0.0163 | 0.0984 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0065 | 0.0051 | 0.0165 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0106 | 0.0143 | 0.0092 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0065 | 0.0051 | 0.0209 |
Trichomonas vaginalis | heat shock protein, putative | 0.014 | 0.0218 | 0.1388 |
Mycobacterium ulcerans | integral membrane indolylacetylinositol arabinosyltransferase EmbC | 0.4557 | 1 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0191 | 0.0332 | 0.2435 |
Treponema pallidum | DNA topoisomerase I (topA) | 0.0115 | 0.0163 | 0.0338 |
Trypanosoma brucei | DNA topoisomerase III, putative | 0.0115 | 0.0163 | 0.0662 |
Echinococcus granulosus | heat shock protein 90 | 0.0106 | 0.0143 | 0.0835 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0048 | 0.0196 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Giardia lamblia | Pms1-like protein | 0.0085 | 0.0098 | 0.04 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0066 | 0.0055 | 0.0194 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0191 | 0.0332 | 0.2222 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Schistosoma mansoni | heat shock protein | 0.0191 | 0.0332 | 0.2222 |
Mycobacterium ulcerans | two component regulator - sensor kinase | 0.0085 | 0.0098 | 0.0046 |
Plasmodium falciparum | heat shock protein 90 | 0.0191 | 0.0332 | 0.091 |
Mycobacterium ulcerans | two component sensor histidine kinase PrrB | 0.0085 | 0.0098 | 0.0046 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0191 | 0.0332 | 0.2222 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.005 | 0.002 | 0.0081 |
Mycobacterium ulcerans | DNA gyrase subunit A | 0.0434 | 0.0869 | 0.0822 |
Trichomonas vaginalis | prokaryotic DNA topoisomerase, putative | 0.0115 | 0.0163 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.0367 | 0.0721 | 0.5074 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0207 | 0.0367 | 0.2477 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0065 | 0.0051 | 0.0068 |
Entamoeba histolytica | DNA topoisomerase III, putative | 0.0115 | 0.0163 | 0.0984 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0048 | 0.0196 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0191 | 0.0332 | 0.2222 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0085 | 0.0098 | 0.0503 |
Chlamydia trachomatis | DNA gyrase subunit A | 0.0434 | 0.0869 | 0.2366 |
Mycobacterium ulcerans | two component sensor kinase MprB | 0.0085 | 0.0098 | 0.0046 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0106 | 0.0143 | 0.0793 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.067 | 0.1392 | 0.3499 |
Brugia malayi | kinase, mitochondrial precursor | 0.0085 | 0.0098 | 0.0503 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0191 | 0.0332 | 0.1564 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0106 | 0.0143 | 0.0579 |
Trichomonas vaginalis | heat shock protein, putative | 0.0106 | 0.0143 | 0.0835 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.067 | 0.1392 | 1 |
Leishmania major | developmentally regulated phosphoprotein-like protein | 0.0085 | 0.0098 | 0.0281 |
Trypanosoma cruzi | DNA topoisomerase III, putative | 0.0115 | 0.0163 | 0.0662 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0071 | 0.0065 | 0.0261 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0065 | 0.0261 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0065 | 0.0261 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0294 | 0.056 | 0.227 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0139 | 0.0217 | 0.077 |
Echinococcus granulosus | DNA topoisomerase 3 alpha | 0.0115 | 0.0163 | 0.0984 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0555 | 0.1137 | 0.4612 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.1557 | 0.3357 | 1 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0106 | 0.0143 | 0.0092 |
Mycobacterium ulcerans | integral membrane indolylacetylinositol arabinosyltransferase EmbB | 0.4557 | 1 | 1 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.1155 | 0.2466 | 1 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0106 | 0.0143 | 0.0835 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0048 | 0.0196 |
Mycobacterium ulcerans | two component system membrane associated sensor kinase | 0.0085 | 0.0098 | 0.0046 |
Plasmodium falciparum | DNA gyrase subunit A | 0.0434 | 0.0869 | 0.2523 |
Trypanosoma brucei | heat shock protein, putative | 0.0191 | 0.0332 | 0.1346 |
Plasmodium vivax | hypothetical protein, conserved | 0.0085 | 0.0098 | 0.0206 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0064 | 0.005 | 0.0154 |
Leishmania major | DNA topoisomerase 1A | 0.0115 | 0.0163 | 0.055 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0257 | 0.0478 | 0.0429 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0555 | 0.1137 | 0.4612 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0066 | 0.0055 | 0.0194 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0066 | 0.0055 | 0.0068 |
Trypanosoma cruzi | DNA topoisomerase III, putative | 0.0115 | 0.0163 | 0.0662 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.1557 | 0.3357 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0048 | 0.0196 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0191 | 0.0332 | 0.1346 |
Loa Loa (eye worm) | hypothetical protein | 0.0226 | 0.0409 | 0.2791 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0048 | 0.0196 |
Echinococcus granulosus | Pyruvate dehydrogenase lipoamide kinase | 0.0085 | 0.0098 | 0.0503 |
Plasmodium vivax | endoplasmin, putative | 0.0191 | 0.0332 | 0.091 |
Schistosoma mansoni | ap endonuclease | 0.0065 | 0.0051 | 0.0165 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0191 | 0.0332 | 0.1346 |
Mycobacterium tuberculosis | Two component sensor histidine kinase PrrB | 0.0085 | 0.0098 | 0.0046 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0191 | 0.0332 | 0.1346 |
Trichomonas vaginalis | mismatch repair protein Mlh1C (mutL homolog) | 0.0085 | 0.0098 | 0.0503 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0294 | 0.056 | 0.227 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0054 | 0.0029 | 0.0076 |
Trichomonas vaginalis | sensor histidine kinase, putative | 0.0085 | 0.0098 | 0.0503 |
Trichomonas vaginalis | heat shock protein, putative | 0.0106 | 0.0143 | 0.0835 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0139 | 0.0217 | 0.0879 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0058 | 0.0036 | 0.0147 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0066 | 0.0055 | 0.0194 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0054 | 0.0029 | 0.0076 |
Trichomonas vaginalis | two component sensor and regulator histidine kinase bacteria, putative | 0.0085 | 0.0098 | 0.0503 |
Brugia malayi | DNA topoisomerase III | 0.0115 | 0.0163 | 0.0984 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0555 | 0.1137 | 0.4612 |
Loa Loa (eye worm) | DNA topoisomerase III beta-1 | 0.0115 | 0.0163 | 0.0984 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0191 | 0.0332 | 0.1346 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0063 | 0.0048 | 0.0196 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0098 | 0.0503 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.058 | 0.1193 | 1 |
Mycobacterium ulcerans | putative regultory protein | 0.0085 | 0.0098 | 0.0046 |
Brugia malayi | Pre-SET motif family protein | 0.0463 | 0.0933 | 0.6636 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0191 | 0.0332 | 0.1346 |
Mycobacterium tuberculosis | Possible two component sensor kinase TcrY | 0.0085 | 0.0098 | 0.0046 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0137 | 0.0211 | 0.0857 |
Treponema pallidum | DNA gyrase, subunit A (gyrA) | 0.0434 | 0.0869 | 0.2472 |
Toxoplasma gondii | exonuclease III APE | 0.0065 | 0.0051 | 0.0187 |
Leishmania major | DNA topoisomerase III, putative | 0.0115 | 0.0163 | 0.055 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0066 | 0.0055 | 0.0068 |
Mycobacterium tuberculosis | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0434 | 0.0869 | 0.0822 |
Mycobacterium ulcerans | integral membrane indolylacetylinositol arabinosyltransferase EmbA | 0.4557 | 1 | 1 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.1072 | 0.2284 | 0.6706 |
Trypanosoma cruzi | DNA topoisomerase IA, putative | 0.0115 | 0.0163 | 0.0662 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0085 | 0.0098 | 0.0503 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0055 | 0.0194 |
Trypanosoma brucei | heat shock protein, putative | 0.0191 | 0.0332 | 0.1346 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0139 | 0.0217 | 0.0879 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0085 | 0.0098 | 0.0413 |
Trypanosoma brucei | heat shock protein, putative | 0.0191 | 0.0332 | 0.1346 |
Plasmodium falciparum | DNA gyrase subunit B | 0.1557 | 0.3357 | 1 |
Leishmania major | DNA topoisomerase III, putative | 0.0115 | 0.0163 | 0.055 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0191 | 0.0332 | 0.1346 |
Toxoplasma gondii | DNA gyrase/topoisomerase IV, A subunit domain-containing protein | 0.0434 | 0.0869 | 0.4202 |
Plasmodium falciparum | DNA topoisomerase VI, b subunit, putative | 0.0085 | 0.0098 | 0.0206 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Mycobacterium leprae | Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) | 0.0523 | 0.1066 | 0.0978 |
Brugia malayi | hypothetical protein | 0.0071 | 0.0065 | 0.0261 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0085 | 0.0098 | 0.0503 |
Schistosoma mansoni | prokaryotic DNA topoisomerase | 0.0115 | 0.0163 | 0.0984 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.067 | 0.1392 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0066 | 0.0055 | 0.0194 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0294 | 0.056 | 0.2178 |
Mycobacterium tuberculosis | Probable sensor protein KdpD | 0.0085 | 0.0098 | 0.0046 |
Trypanosoma cruzi | DNA topoisomerase IA, putative | 0.0115 | 0.0163 | 0.0662 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1813 | 0.3924 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0207 | 0.0367 | 0.2477 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 0.0348 | 0.2337 |
Trypanosoma brucei | developmentally regulated phosphoprotein | 0.0085 | 0.0098 | 0.0396 |
Echinococcus multilocularis | rho GTPase activating protein 20 | 0.0115 | 0.0163 | 0.0344 |
Mycobacterium tuberculosis | Integral membrane indolylacetylinositol arabinosyltransferase EmbA (arabinosylindolylacetylinositol synthase) | 0.4557 | 1 | 1 |
Mycobacterium ulcerans | two component system response phosphate sensor kinase, PhoR | 0.0085 | 0.0098 | 0.0046 |
Trypanosoma brucei | heat shock protein, putative | 0.0191 | 0.0332 | 0.1346 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0048 | 0.0079 |
Mycobacterium tuberculosis | Possible two component system response sensor kinase membrane associated PhoR | 0.0085 | 0.0098 | 0.0046 |
Echinococcus granulosus | geminin | 0.0198 | 0.0348 | 0.2337 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0071 | 0.0065 | 0.0091 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0065 | 0.0261 |
Trypanosoma brucei | heat shock protein, putative | 0.0191 | 0.0332 | 0.1346 |
Loa Loa (eye worm) | glutaminase | 0.0271 | 0.0508 | 0.3515 |
Leishmania major | DNA topoisomerase ii | 0.0555 | 0.1137 | 0.4548 |
Trypanosoma brucei | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0085 | 0.0098 | 0.0396 |
Schistosoma mansoni | DNA topoisomerase II | 0.067 | 0.1392 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0065 | 0.0051 | 0.0209 |
Plasmodium vivax | DNA gyrase subunit A, putative | 0.0434 | 0.0869 | 0.2523 |
Trypanosoma cruzi | heat shock protein, putative | 0.0054 | 0.0029 | 0.0118 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0065 | 0.0051 | 0.0092 |
Trypanosoma brucei | DNA topoisomerase III, putative | 0.0115 | 0.0163 | 0.0662 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DevS | 0.0085 | 0.0098 | 0.0046 |
Mycobacterium ulcerans | glutaminase | 0.0271 | 0.0508 | 0.0459 |
Mycobacterium ulcerans | DNA topoisomerase I | 0.0115 | 0.0163 | 0.0112 |
Brugia malayi | GRF zinc finger family protein | 0.0115 | 0.0163 | 0.0984 |
Plasmodium falciparum | endoplasmin, putative | 0.014 | 0.0218 | 0.0568 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0207 | 0.0367 | 0.2477 |
Loa Loa (eye worm) | DNA topoisomerase III | 0.0115 | 0.0163 | 0.0984 |
Schistosoma mansoni | heat shock protein | 0.0191 | 0.0332 | 0.2222 |
Trypanosoma brucei | heat shock protein, putative | 0.0191 | 0.0332 | 0.1346 |
Trypanosoma cruzi | developmentally regulated phosphoprotein, putative | 0.0085 | 0.0098 | 0.0396 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0106 | 0.0143 | 0.0467 |
Mycobacterium ulcerans | hypothetical protein | 0.0155 | 0.0252 | 0.0201 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0085 | 0.0098 | 0.0503 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0555 | 0.1137 | 0.4612 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0065 | 0.0051 | 0.0165 |
Trichomonas vaginalis | heat shock protein, putative | 0.0191 | 0.0332 | 0.2222 |
Mycobacterium ulcerans | two component sensor histidine kinase DevS | 0.0085 | 0.0098 | 0.0046 |
Giardia lamblia | DNA topoisomerase II | 0.0584 | 0.1203 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0048 | 0.0196 |
Mycobacterium ulcerans | DNA gyrase subunit B | 0.1557 | 0.3357 | 0.3323 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0048 | 0.0196 |
Treponema pallidum | heat shock protein 90 | 0.0106 | 0.0143 | 0.0276 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0155 | 0.0252 | 0.0201 |
Echinococcus granulosus | endoplasmin | 0.0106 | 0.0143 | 0.0835 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0207 | 0.0367 | 0.2477 |
Mycobacterium tuberculosis | Integral membrane indolylacetylinositol arabinosyltransferase EmbB (arabinosylindolylacetylinositol synthase) | 0.4557 | 1 | 1 |
Trichomonas vaginalis | sensory transduction histidine kinase, putative | 0.0085 | 0.0098 | 0.0503 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0106 | 0.0143 | 0.0579 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase subunit A | 0.0434 | 0.0869 | 0.2472 |
Mycobacterium tuberculosis | Two component sensor kinase [second part] | 0.0085 | 0.0098 | 0.0046 |
Brugia malayi | Probable DNA topoisomerase II | 0.067 | 0.1392 | 1 |
Onchocerca volvulus | 0.0115 | 0.0163 | 0.1152 | |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0207 | 0.0367 | 0.2477 |
Echinococcus multilocularis | heat shock protein 90 | 0.0106 | 0.0143 | 0.0292 |
Echinococcus multilocularis | DNA topoisomerase 3 beta 1 | 0.0115 | 0.0163 | 0.0344 |
Mycobacterium tuberculosis | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.1557 | 0.3357 | 0.3323 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.067 | 0.1392 | 0.4095 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0071 | 0.0065 | 0.0261 |
Echinococcus granulosus | DNA topoisomerase 3 beta 1 | 0.0115 | 0.0163 | 0.0984 |
Trypanosoma brucei | DNA topoisomerase IA, putative | 0.0115 | 0.0163 | 0.0662 |
Echinococcus granulosus | heat shock protein | 0.0191 | 0.0332 | 0.2222 |
Trypanosoma brucei | heat shock protein, putative | 0.0191 | 0.0332 | 0.1346 |
Brugia malayi | Endoplasmin precursor | 0.0191 | 0.0332 | 0.2222 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.005 | 0.0018 | 0.0075 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0065 | 0.0051 | 0.0165 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0066 | 0.0055 | 0.0206 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 0.0348 | 0.2337 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0294 | 0.056 | 0.227 |
Echinococcus multilocularis | geminin | 0.0198 | 0.0348 | 0.0818 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0066 | 0.0055 | 0.0194 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0048 | 0.0196 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.067 | 0.1392 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Echinococcus multilocularis | heat shock protein 90 | 0.0191 | 0.0332 | 0.0778 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.067 | 0.1392 | 0.6772 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.058 | 0.1193 | 1 |
Trypanosoma cruzi | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0085 | 0.0098 | 0.0396 |
Mycobacterium ulcerans | two component sensor histidine kinase TrcS | 0.0085 | 0.0098 | 0.0046 |
Schistosoma mansoni | endoplasmin | 0.0191 | 0.0332 | 0.2222 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0207 | 0.0367 | 0.2477 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0066 | 0.0055 | 0.0194 |
Brugia malayi | heat shock protein 90 | 0.0191 | 0.0332 | 0.2222 |
Plasmodium falciparum | DNA topoisomerase 3, putative | 0.0115 | 0.0163 | 0.0403 |
Schistosoma mansoni | glutaminase | 0.0271 | 0.0508 | 0.3515 |
Trichomonas vaginalis | prokaryotic DNA topoisomerase, putative | 0.0115 | 0.0163 | 0.0984 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Mycobacterium leprae | Probable integral membrane indolylacetylinositol arabinosyltransferase EmbB (arabinosylindolylacetylinositol synthase) | 0.4557 | 1 | 1 |
Mycobacterium leprae | Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( | 0.0115 | 0.0163 | 0.0066 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0106 | 0.0143 | 0.0276 |
Giardia lamblia | DNA topoisomerase III | 0.0115 | 0.0163 | 0.097 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0065 | 0.0051 | 0.0165 |
Giardia lamblia | DNA topoisomerase III | 0.0115 | 0.0163 | 0.097 |
Brugia malayi | DNA topoisomerase III beta-1 | 0.0115 | 0.0163 | 0.0984 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Trypanosoma cruzi | DNA topoisomerase III, putative | 0.0115 | 0.0163 | 0.0662 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.067 | 0.1392 | 1 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0048 | 0.0079 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0065 | 0.0261 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0085 | 0.0098 | 0.0176 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0115 | 0.0163 | 0.0201 |
Plasmodium vivax | DNA topoisomerase 3, putative | 0.0115 | 0.0163 | 0.0403 |
Mycobacterium tuberculosis | Two component sensor kinase MprB | 0.0085 | 0.0098 | 0.0046 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.067 | 0.1392 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0191 | 0.0332 | 0.1346 |
Loa Loa (eye worm) | glutaminase 2 | 0.0271 | 0.0508 | 0.3515 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0065 | 0.0051 | 0.0209 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0207 | 0.0367 | 0.0867 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0191 | 0.0332 | 0.1564 |
Mycobacterium tuberculosis | Two component sensory transduction histidine kinase MtrB | 0.0085 | 0.0098 | 0.0046 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0048 | 0.0196 |
Toxoplasma gondii | DNA topoisomerase family protein | 0.0115 | 0.0163 | 0.0735 |
Mycobacterium ulcerans | two component sensor histidine kinase SenX3 | 0.0085 | 0.0098 | 0.0046 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.0085 | 0.0098 | 0.0503 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0065 | 0.0051 | 0.0058 |
Schistosoma mansoni | endoplasmin | 0.0191 | 0.0332 | 0.2222 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0191 | 0.0332 | 0.1346 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.067 | 0.1392 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0065 | 0.0051 | 0.0165 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.1155 | 0.2466 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0106 | 0.0143 | 0.0835 |
Giardia lamblia | Grp94/Hsp90 | 0.0106 | 0.0143 | 0.0793 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Mycobacterium tuberculosis | Integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase) | 0.4557 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0085 | 0.0098 | 0.0281 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0085 | 0.0098 | 0.0413 |
Trypanosoma brucei | DNA topoisomerase ii | 0.1155 | 0.2466 | 1 |
Mycobacterium tuberculosis | Two component sensor histidine kinase TrcS | 0.0085 | 0.0098 | 0.0046 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0054 | 0.0029 | 0.0118 |
Wolbachia endosymbiont of Brugia malayi | topoisomerase IA, TopA | 0.0115 | 0.0163 | 0.0338 |
Echinococcus granulosus | heat shock protein 90 | 0.0191 | 0.0332 | 0.2222 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0048 | 0.0196 |
Leishmania major | heat shock protein 83-1 | 0.0191 | 0.0332 | 0.1243 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0065 | 0.0051 | 0.0068 |
Mycobacterium leprae | Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) | 0.0178 | 0.0303 | 0.0208 |
Wolbachia endosymbiont of Brugia malayi | membrane associated signal transduction histidine kinase | 0.0085 | 0.0098 | 0.0139 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0065 | 0.0051 | 0.0165 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.