Detailed information for compound 996565

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 266.377 | Formula: C19H22O
  • H donors: 0 H acceptors: 1 LogP: 4.47 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=CC1=CC=C([C@@H]([C@@H]1c1ccccc1)CC=C(C)C)C
  • InChi: 1S/C19H22O/c1-14(2)9-12-18-15(3)10-11-17(13-20)19(18)16-7-5-4-6-8-16/h4-11,13,18-19H,12H2,1-3H3/t18-,19+/m0/s1
  • InChiKey: GDRAAEYZBGZMBO-RBUKOAKNSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0127 0.0421
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0326 0.1135
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0127 0.0727
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0034 0.0085
Leishmania major importin beta-1 subunit, putative 0.0048 0.0311 0.1081
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0438 0.0438
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0702 0.6369 1
Plasmodium vivax vivapain-2 0.0018 0.0034 0.0272
Echinococcus multilocularis neuropeptide FF receptor 2 0.0061 0.0438 0.0438
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0331 0.2933 0.2933
Brugia malayi Serotonin receptor 0.0061 0.0438 0.0784
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0108
Onchocerca volvulus 0.0232 0.2019 0.3614
Echinococcus granulosus g protein coupled receptor 0.0061 0.0438 0.0438
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0034 0.006
Leishmania major GTP-binding protein, putative 0.0023 0.0078 0.0244
Echinococcus granulosus dna polymerase kappa 0.0022 0.0072 0.0072
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0318 0.0318
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0886 0.4387
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0072 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.0326 0.3615
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.011 0.0886 0.1378
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0415 0.0415
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0072 0.0227
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0072 0.0227
Toxoplasma gondii ABC1 family protein 0.011 0.0886 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Leishmania major cathepsin L-like protease 0.0018 0.0034 0.0085
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Brugia malayi Dopamine receptor protein 1 0.0061 0.0438 0.0784
Mycobacterium tuberculosis Conserved protein 0.011 0.0886 0.1378
Onchocerca volvulus 0.0061 0.0438 0.0784
Onchocerca volvulus 0.011 0.0886 0.1586
Loa Loa (eye worm) hypothetical protein 0.032 0.2831 0.4966
Echinococcus granulosus alpha 1A adrenergic receptor 0.0061 0.0438 0.0438
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0331 0.2933 0.2933
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Echinococcus granulosus dna polymerase eta 0.0022 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0049 0.0326 0.0573
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0916 0.4537
Schistosoma mansoni biogenic amine receptor 0.0061 0.0438 0.0438
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0371 0.1294
Schistosoma mansoni neuropeptide receptor 0.0061 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.024 0.0363
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0188 0.161 0.161
Schistosoma mansoni methyl-cpg binding protein mbd 0.0053 0.0357 0.0357
Brugia malayi hypothetical protein 0.0061 0.0438 0.0784
Brugia malayi glutathione reductase 0.0049 0.0324 0.058
Echinococcus multilocularis orexin receptor type 2 0.0061 0.0438 0.0438
Schistosoma mansoni zinc finger protein 0.0047 0.0306 0.0306
Brugia malayi RNA recognition motif domain containing protein 0.0343 0.3044 0.5449
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0415 0.1454
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0061 0.0438 0.0438
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0061 0.0438 0.0768
Onchocerca volvulus 0.0061 0.0438 0.0784
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.001 0.001
Mycobacterium ulcerans esterase/lipase LipP 0.011 0.0886 0.62
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0072 0.0098
Schistosoma mansoni bromodomain containing protein 0.0017 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0022 0.0074 0.0074
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0127 0.1367
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0034 0.0361
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.011 0.0886 0.1586
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0127 0.0228
Echinococcus multilocularis neuropeptide receptor A26 0.0061 0.0438 0.0438
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.0886 0.314
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0151 0.1617
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0281 0.0974
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0324 0.1127
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0311 0.1081
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0318 0.3514
Loa Loa (eye worm) hypothetical protein 0.011 0.0886 0.1554
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0072 0.0227
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0438 0.0438
Echinococcus multilocularis serotonin receptor 0.0061 0.0438 0.0438
Onchocerca volvulus 0.0029 0.0139 0.025
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0034 0.0361
Onchocerca volvulus 0.0061 0.0438 0.0784
Brugia malayi Pre-SET motif family protein 0.0204 0.1758 0.3147
Onchocerca volvulus 0.0018 0.0034 0.006
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0061 0.0438 0.0784
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0151 0.075
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0061 0.0438 0.0438
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0034 0.006
Loa Loa (eye worm) glutathione reductase 0.0049 0.0324 0.0569
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0438 0.0768
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0438 0.0438
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.015 0.1256 0.4466
Echinococcus multilocularis snurportin 1 0.063 0.5701 0.5701
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0062 0.2831
Echinococcus granulosus allatostatin A receptor 0.0061 0.0438 0.0438
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.0326 0.3615
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0082 0.0628 0.0628
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0061 0.0438 0.0768
Toxoplasma gondii cathepsin CPL 0.0018 0.0034 0.0272
Brugia malayi Tachykinin-like peptides receptor 99D 0.0061 0.0438 0.0784
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0438 0.0438
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0034 0.0034
Mycobacterium ulcerans hypothetical protein 0.011 0.0886 0.62
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0326 0.7821
Schistosoma mansoni histamine h1 receptor 0.0061 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0026 0.0059
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0324 0.3588
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0051 0.0065
Trypanosoma cruzi ISWI complex protein 0.0047 0.0306 0.1063
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0034 0.0166
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0072 0.0227
Schistosoma mansoni amine GPCR 0.0061 0.0438 0.0438
Brugia malayi Latrophilin receptor protein 2 0.0148 0.124 0.2219
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.024 0.5696
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.0908 0.1413
Schistosoma mansoni ap endonuclease 0.004 0.024 0.024
Echinococcus granulosus cathepsin l1 0.0018 0.0034 0.0034
Brugia malayi Thioredoxin reductase 0.0049 0.0324 0.058
Echinococcus multilocularis cysteine protease 0.0018 0.0034 0.0034
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0072 0.0072
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0078 0.0776
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0498 0.1752
Schistosoma mansoni tar DNA-binding protein 0.0343 0.3044 0.3044
Echinococcus multilocularis neuropeptide receptor 0.0061 0.0438 0.0438
Brugia malayi hypothetical protein 0.0061 0.0438 0.0784
Brugia malayi G protein-coupled receptor 0.0061 0.0438 0.0784
Loa Loa (eye worm) hypothetical protein 0.0028 0.0127 0.0223
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Schistosoma mansoni zinc finger protein 0.0064 0.0461 0.0461
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0034 0.0034
Echinococcus granulosus g protein coupled receptor 0.0061 0.0438 0.0438
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0026 0.0059
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.0908 0.1413
Brugia malayi 6-phosphofructokinase 0.0113 0.0916 0.164
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0061 0.0438 0.0784
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0363 0.1266
Onchocerca volvulus 0.0061 0.0438 0.0784
Echinococcus granulosus G protein coupled receptor 139 0.0061 0.0438 0.0438
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0026 0.0059
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0034 0.0034
Trichomonas vaginalis ap endonuclease, putative 0.004 0.024 0.1191
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0078 0.0244
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0108
Brugia malayi TAR-binding protein 0.0343 0.3044 0.5449
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0438 0.0438
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0034 0.006
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Schistosoma mansoni hypothetical protein 0.0061 0.0438 0.0438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Loa Loa (eye worm) RNA binding protein 0.0343 0.3044 0.534
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0129 0.0129
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0139 0.0139
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0498 0.1749
Onchocerca volvulus Neuropeptide F receptor homolog 0.0061 0.0438 0.0784
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0139 0.148
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0438 0.0438
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0034 0.0166
Leishmania major cathepsin L-like protease 0.0068 0.0498 0.1749
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.001 0.001
Schistosoma mansoni neuropeptide receptor 0.0061 0.0438 0.0438
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0886 0.4387
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0034 0.0166
Echinococcus multilocularis dro:myosuppressin receptor 0.0061 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0119 0.0967 0.1697
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0916 0.9852
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0438 0.0438
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0438 0.0438
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0127 0.0228
Brugia malayi Dopamine receptor 0.0061 0.0438 0.0784
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0034 0.0166
Onchocerca volvulus 0.011 0.0886 0.1586
Echinococcus granulosus sex peptide receptor 0.0061 0.0438 0.0438
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0026 0.0026
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0916 0.9852
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0438 0.0438
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0331 0.2933 0.2933
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0331 0.2933 0.2933
Brugia malayi 6-phosphofructokinase 0.0113 0.0916 0.164
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Brugia malayi hypothetical protein 0.0061 0.0438 0.0784
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0438 0.0438
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.1233 0.2208
Echinococcus granulosus 7TM GPCR rhodopsin 0.0061 0.0438 0.0438
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.0908 0.1413
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0151 0.075
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0072 0.0227
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0916 0.0916
Brugia malayi ORL1-like opioid receptor 0.0061 0.0438 0.0784
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0061 0.0438 0.0438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0343 0.3044 0.534
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0082 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.011 0.0886 0.1554
Loa Loa (eye worm) hypothetical protein 0.011 0.0886 0.1554
Brugia malayi hypothetical protein 0.0061 0.0438 0.0784
Brugia malayi GnHR receptor homolog 0.0061 0.0438 0.0784
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0062 0.1283
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.0908 0.1413
Trypanosoma brucei hypothetical protein, conserved 0.011 0.0886 0.3142
Onchocerca volvulus 0.0018 0.0034 0.006
Schistosoma mansoni hypothetical protein 0.0148 0.124 0.124
Onchocerca volvulus 0.0061 0.0438 0.0784
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0316 0.28 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.001 0.001
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0438 0.0438
Onchocerca volvulus 0.0061 0.0438 0.0784
Entamoeba histolytica hypothetical protein 0.0115 0.093 1
Schistosoma mansoni hypothetical protein 0.0148 0.124 0.124
Echinococcus granulosus neuropeptide receptor A26 0.0061 0.0438 0.0438
Schistosoma mansoni amine GPCR 0.0061 0.0438 0.0438
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0072 0.0072
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0316 0.28 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.011 0.0886 0.62
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.0886 0.0886
Echinococcus multilocularis G protein coupled receptor 139 0.0061 0.0438 0.0438
Echinococcus multilocularis dna polymerase eta 0.0022 0.0072 0.0072
Brugia malayi hypothetical protein 0.0115 0.093 0.1664
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.063 0.5701 1
Brugia malayi G-protein coupled receptor 0.0061 0.0438 0.0784
Schistosoma mansoni hypothetical protein 0.0047 0.0306 0.0306
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0026 0.013
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Brugia malayi AKH receptor 0.0061 0.0438 0.0784
Plasmodium falciparum glutathione reductase 0.0049 0.0324 0.7764
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Echinococcus granulosus dro:myosuppressin receptor 0.0061 0.0438 0.0438
Mycobacterium tuberculosis Probable hydrolase 0.011 0.0886 0.1378
Schistosoma mansoni neuropeptide f receptor 76f 0.0061 0.0438 0.0438
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.011 0.0886 0.1378
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0026 0.0059
Brugia malayi hypothetical protein 0.0032 0.0164 0.0294
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0026 0.0408
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Echinococcus multilocularis neuropeptide receptor 0.0061 0.0438 0.0438
Entamoeba histolytica hypothetical protein 0.0115 0.093 1
Trichomonas vaginalis ran, putative 0.0023 0.0078 0.0385
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.0886 0.4387
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.004
Schistosoma mansoni biogenic amine receptor 0.0061 0.0438 0.0438
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0061 0.0438 0.0438
Onchocerca volvulus 0.0061 0.0438 0.0784
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0127 0.0727
Schistosoma mansoni amine GPCR 0.0061 0.0438 0.0438
Leishmania major DNA polymerase kappa, putative 0.0022 0.0072 0.0223
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0026 0.0062
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0415 0.1454
Leishmania major trypanothione reductase 0.0049 0.0324 0.1127
Leishmania major hypothetical protein, conserved 0.0047 0.0306 0.1063
Brugia malayi RNA, U transporter 1 0.0168 0.1422 0.2545
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Onchocerca volvulus 0.0061 0.0438 0.0784
Brugia malayi hypothetical protein 0.0061 0.0438 0.0784
Mycobacterium tuberculosis Conserved hypothetical protein 0.0167 0.1413 0.2206
Schistosoma mansoni biogenic amine receptor 0.0061 0.0438 0.0438
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.001 0.001
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0151 0.075
Schistosoma mansoni ap endonuclease 0.004 0.024 0.024
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0072 0.0227
Echinococcus granulosus histone lysine methyltransferase setb 0.0082 0.0628 0.0628
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0498 0.1752
Echinococcus granulosus beta LACTamase domain containing family member 0.011 0.0886 0.0886
Echinococcus granulosus methyl CpG binding domain protein 2 0.0053 0.0357 0.0357
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Entamoeba histolytica cysteine protease, putative 0.0018 0.0034 0.0361
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0034 0.0166
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0061 0.0438 0.0438
Echinococcus granulosus orexin receptor type 2 0.0061 0.0438 0.0438
Brugia malayi hypothetical protein 0.0061 0.0438 0.0784
Echinococcus multilocularis g-protein coupled receptor 0.0061 0.0438 0.0438
Echinococcus granulosus tar DNA binding protein 0.0343 0.3044 0.3044
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0324 0.0324
Echinococcus granulosus hypothetical protein 0.0061 0.0438 0.0438
Echinococcus granulosus fmrfamide receptor 0.0061 0.0438 0.0438
Brugia malayi beta-lactamase family protein 0.011 0.0886 0.1586
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0061 0.0438 0.0438
Loa Loa (eye worm) PHD-finger family protein 0.0064 0.0459 0.0806
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0026 0.013
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0916 0.325
Plasmodium vivax importin-beta 2, putative 0.0059 0.0415 0.4622
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0061 0.0438 0.0784
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0151 0.3498
Echinococcus granulosus neuropeptide FF receptor 2 0.0061 0.0438 0.0438
Onchocerca volvulus 0.0028 0.0127 0.0228
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0072 0.0227
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0468 0.4202 0.7522
Brugia malayi beta-lactamase 0.011 0.0886 0.1586
Schistosoma mansoni myosin xvIII 0.0061 0.0438 0.0438
Trypanosoma brucei unspecified product 0.0022 0.0072 0.0227
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0438 0.0438
Brugia malayi Serotonin receptor 0.0061 0.0438 0.0784
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0331 0.2933 0.2933
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0072 0.0227
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0139 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Schistosoma mansoni opsin-like receptor 0.0061 0.0438 0.0438
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0034 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0022 0.0072 0.0126
Schistosoma mansoni hypothetical protein 0.0115 0.093 0.093
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0061 0.0438 0.0438
Brugia malayi hypothetical protein 0.0061 0.0438 0.0784
Onchocerca volvulus 0.0061 0.0438 0.0784
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0438 0.0438
Plasmodium falciparum thioredoxin reductase 0.0017 0.0026 0.0408
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0438 0.0438
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0151 0.1617
Schistosoma mansoni DNA polymerase eta 0.0022 0.0072 0.0072
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0127 0.1367
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0886 0.4387
Brugia malayi hypothetical protein 0.0061 0.0438 0.0784
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0111 0.0897 0.0897
Entamoeba histolytica acyl-coA synthetase, putative 0.0028 0.0127 0.1367
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.0886 0.0886
Leishmania major cathepsin L-like protease 0.0018 0.0034 0.0085
Onchocerca volvulus 0.0018 0.0034 0.006
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0061 0.0438 0.0438
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0151 0.1617
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0034 0.0166
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0151 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0281 0.0971
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0127 0.0727
Brugia malayi Bromodomain containing protein 0.0235 0.2048 0.3666
Echinococcus granulosus g protein coupled receptor 0.0061 0.0438 0.0438
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0916 0.1607
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0026 0.0062
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0916 0.4537
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0034 0.006
Loa Loa (eye worm) fibroinase 0.0018 0.0034 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0498 0.1752
Schistosoma mansoni tar DNA-binding protein 0.0343 0.3044 0.3044
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0061 0.0438 0.0768
Echinococcus multilocularis G-protein coupled receptor, putative 0.0061 0.0438 0.0438
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.024 0.0422
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0916 0.9852
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0072 0.0223
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.011 0.0886 0.1554
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0281 0.0971
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.0443 0.1553
Trichomonas vaginalis ap endonuclease, putative 0.004 0.024 0.1191
Schistosoma mansoni bromodomain containing protein 0.0199 0.1712 0.1712
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0072 0.0227
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0061 0.0438 0.0438
Brugia malayi G-protein coupled receptor 0.0061 0.0438 0.0784
Echinococcus granulosus serotonin receptor 0.0061 0.0438 0.0438
Mycobacterium tuberculosis Probable lipase LipD 0.011 0.0886 0.1378
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0026 0.0059
Brugia malayi isocitrate dehydrogenase 0.0015 0.001 0.0017
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.007 0.0514 0.0514
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0078 0.0776
Echinococcus multilocularis fetal alzheimer antigen, falz 0.007 0.0514 0.0514
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.001 0.0017
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0331 0.2933 0.525
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0127 0.0727
Leishmania major hypothetical protein, conserved 0.0049 0.0326 0.1135
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0688 0.624 0.624
Loa Loa (eye worm) hypothetical protein 0.011 0.0886 0.1554
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0316 0.28 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0078 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0498 0.1752
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0061 0.0438 0.0438
Schistosoma mansoni adenoreceptor 0.0061 0.0438 0.0438
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0438 0.0438
Toxoplasma gondii exonuclease III APE 0.004 0.024 0.2633
Leishmania major cathepsin L-like protease 0.0018 0.0034 0.0085
Echinococcus granulosus g-protein coupled receptor 0.0061 0.0438 0.0438
Mycobacterium ulcerans hypothetical protein 0.0167 0.1413 1
Mycobacterium tuberculosis Probable reductase 0.0112 0.0908 0.1413
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0026 0.0059
Toxoplasma gondii hypothetical protein 0.0051 0.0341 0.3783
Brugia malayi Pre-SET motif family protein 0.0029 0.0139 0.025
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0072 0.0227
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0151 0.1617
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.024 0.0827
Loa Loa (eye worm) hypothetical protein 0.0028 0.0127 0.0223
Echinococcus granulosus neuropeptide s receptor 0.0061 0.0438 0.0438
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0151 0.1406
Echinococcus granulosus biogenic amine 5HT receptor 0.0061 0.0438 0.0438
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0281 0.0971
Onchocerca volvulus 0.0061 0.0438 0.0784
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0188 0.161 0.161
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0051 0.0065
Leishmania major cathepsin L-like protease 0.0018 0.0034 0.0085
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0072 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0061 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0108
Echinococcus granulosus 7tm_1 domain containing protein 0.0061 0.0438 0.0438
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.1129 0.1129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Onchocerca volvulus 0.0061 0.0438 0.0784
Leishmania major mitochondrial DNA polymerase beta 0.0316 0.28 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0026 0.0062
Loa Loa (eye worm) hypothetical protein 0.0148 0.124 0.2175
Entamoeba histolytica hypothetical protein 0.0115 0.093 1
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0438 0.0438
Schistosoma mansoni growth hormone secretagogue receptor 0.0061 0.0438 0.0438
Schistosoma mansoni alpha-1 adrenergic receptor 0.0061 0.0438 0.0438
Mycobacterium ulcerans hypothetical protein 0.0028 0.0127 0.0727
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0438 0.0438
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.1024 1
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0438 0.0438
Echinococcus granulosus zinc finger protein 0.0064 0.0461 0.0461
Echinococcus multilocularis cysteine protease 0.0018 0.0034 0.0034
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0916 0.1607
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0127 0.0228
Schistosoma mansoni ran 0.0023 0.0078 0.0078
Onchocerca volvulus 0.0061 0.0438 0.0784
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Brugia malayi larval opioid receptor 0.0061 0.0438 0.0784
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0151 0.075
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0061 0.0438 0.0438
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0326 0.7821
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0026 0.0189
Loa Loa (eye worm) acetyltransferase 0.0147 0.1233 0.2164
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.024 0.043
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0061 0.0438 0.0438
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0072 0.0775
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0324 0.0569
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0438 0.0438
Echinococcus multilocularis GPCR, family 2 0.0148 0.124 0.124
Schistosoma mansoni ran 0.0023 0.0078 0.0078
Trypanosoma brucei trypanothione reductase 0.0049 0.0324 0.113
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0034 0.0166
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0115 0.093 0.093
Plasmodium falciparum thioredoxin reductase 0.0049 0.0324 0.7764
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0135 0.1121 0.1967
Mycobacterium ulcerans lipase LipD 0.011 0.0886 0.62
Trypanosoma cruzi cruzipain precursor, putative 0.0068 0.0498 0.1749
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0026 0.0059
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0078 0.0078
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0078 0.0244
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Echinococcus granulosus snurportin 1 0.063 0.5701 0.5701
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0498 0.1752
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0072 0.0223
Plasmodium vivax hypothetical protein, conserved 0.011 0.0886 1
Schistosoma mansoni hypothetical protein 0.0061 0.0438 0.0438
Trichomonas vaginalis set domain proteins, putative 0.0232 0.2019 1
Loa Loa (eye worm) beta-lactamase 0.011 0.0886 0.1554
Brugia malayi Importin beta-1 subunit 0.0059 0.0415 0.0742
Onchocerca volvulus 0.0061 0.0438 0.0784
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0078 0.0136
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0078 0.2403
Mycobacterium leprae Probable lipase LipE 0.011 0.0886 0.8459
Brugia malayi Calcitonin receptor-like protein seb-1 0.0468 0.4202 0.7522
Brugia malayi RE15519p 0.0061 0.0438 0.0784
Schistosoma mansoni transcription factor LCR-F1 0.0115 0.093 0.093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0498 0.1752
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Brugia malayi Bromodomain containing protein 0.0122 0.0997 0.1784
Brugia malayi Dopamine receptor protein 2 0.0061 0.0438 0.0784
Echinococcus granulosus neuropeptide receptor 0.0061 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0108
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0061 0.0438 0.0784
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0026 0.0026
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0062 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0072 0.0227
Schistosoma mansoni tar DNA-binding protein 0.0343 0.3044 0.3044
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0151 0.075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0498 0.1752
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Echinococcus granulosus tachykinin peptides receptor 99D 0.0061 0.0438 0.0438
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0285 0.2509 0.4402
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0916 0.1607
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0026 0.0059
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0438 0.0438
Loa Loa (eye worm) transcription factor SMAD2 0.0141 0.1171 0.2055
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0078 0.1679
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.024 0.2585
Mycobacterium leprae conserved hypothetical protein 0.011 0.0886 0.8459
Schistosoma mansoni hypothetical protein 0.0064 0.0459 0.0459
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0028 0.0127 0.0185
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0438 0.0438
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.0148 0.124 0.124
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0318 0.1573
Loa Loa (eye worm) hypothetical protein 0.0082 0.0628 0.1101
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.024 0.0827
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0438 0.0438
Echinococcus granulosus importin subunit beta 1 0.0059 0.0415 0.0415
Schistosoma mansoni importin beta-1 0.0059 0.0415 0.0415
Loa Loa (eye worm) TAR-binding protein 0.0343 0.3044 0.534
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0438 0.0438
Mycobacterium tuberculosis Probable esterase LipL 0.011 0.0886 0.1378
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0916 0.8796
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.024 0.083
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0072 0.0357
Brugia malayi Melatonin receptor type 1A 0.0061 0.0438 0.0784
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0331 0.2933 0.2933
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.0886 0.4387
Plasmodium vivax SET domain protein, putative 0.0029 0.0139 0.148
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0916 0.6418
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0072 0.0227
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0111 0.0897 0.0897
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Schistosoma mansoni hypothetical protein 0.0148 0.124 0.124
Onchocerca volvulus 0.0061 0.0438 0.0784
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0331 0.2933 0.2933
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0438 0.0768
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0026 0.0189
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0916 0.4537
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0916 0.3248
Entamoeba histolytica Ran family GTPase 0.0023 0.0078 0.0836
Brugia malayi Cathepsin L-like precursor 0.0018 0.0034 0.006
Leishmania major DNA polymerase eta, putative 0.0022 0.0072 0.0223
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0438 0.0438
Schistosoma mansoni biogenic amine (5HT) receptor 0.0061 0.0438 0.0438
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0026 0.0062
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0078 0.0247
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0438 0.0768
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0438 0.0438
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0034 0.0588
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0438 0.0438
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0082 0.0628 0.0628
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0034 0.0166
Echinococcus granulosus neuropeptide receptor 0.0061 0.0438 0.0438
Leishmania major cathepsin L-like protease 0.0018 0.0034 0.0085
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0061 0.0438 0.0438
Onchocerca volvulus 0.011 0.0886 0.1586
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0061 0.0438 0.0438
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0438 0.0438
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.024 0.2633
Schistosoma mansoni hypothetical protein 0.1094 1 1
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0916 0.3248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0498 0.1752
Echinococcus multilocularis somatostatin receptor 0.0061 0.0438 0.0438
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0034 0.0166
Schistosoma mansoni neuropeptide receptor 0.0061 0.0438 0.0438
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0151 0.3498
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0415 0.4622
Schistosoma mansoni tar DNA-binding protein 0.0343 0.3044 0.3044
Toxoplasma gondii thioredoxin reductase 0.0049 0.0324 0.3588
Loa Loa (eye worm) hypothetical protein 0.011 0.0886 0.1554
Brugia malayi Isocitrate dehydrogenase 0.0015 0.001 0.0017
Brugia malayi G protein-coupled receptor F59B2.13 0.0061 0.0438 0.0784
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0026 0.0189
Onchocerca volvulus 0.0617 0.5587 1
Giardia lamblia DINP protein human, muc B family 0.0022 0.0072 0.2138
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0034 0.0166
Echinococcus multilocularis beta LACTamase domain containing family member 0.011 0.0886 0.0886
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0148 0.124 0.2219
Brugia malayi PHD-finger family protein 0.008 0.0614 0.1098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0468 0.4202 0.7372
Loa Loa (eye worm) hypothetical protein 0.0219 0.1894 0.3322
Schistosoma mansoni hypothetical protein 0.063 0.5701 0.5701
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0148 0.124 0.124
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0026 0.0408
Leishmania major cathepsin L-like protease 0.0068 0.0498 0.1749
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0034 0.0085
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0026 0.0059
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0072 0.0223
Loa Loa (eye worm) ctsf protein 0.0018 0.0034 0.0059
Entamoeba histolytica hypothetical protein 0.0115 0.093 1
Brugia malayi Cathepsin L-like precursor 0.0018 0.0034 0.006
Onchocerca volvulus 0.0018 0.0034 0.006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0438 0.0438
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0072 0.0072
Brugia malayi putative neuropeptide receptor 0.0061 0.0438 0.0784
Leishmania major hypothetical protein, conserved 0.011 0.0886 0.314
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0438 0.0438
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.024 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0028 0.0127 0.0727
Loa Loa (eye worm) MH2 domain-containing protein 0.0141 0.1171 0.2055
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.015 0.1256 0.4466
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Brugia malayi MH2 domain containing protein 0.0141 0.1171 0.2097
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.0908 0.1413
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0062 0.0593
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Schistosoma mansoni biogenic amine (5HT) receptor 0.0061 0.0438 0.0438
Trichomonas vaginalis esterase, putative 0.011 0.0886 0.4387
Trypanosoma brucei ISWI complex protein 0.0047 0.0306 0.1066
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0115 0.093 0.093
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0127 0.0421
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0438 0.0438
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0053 0.0357 0.0357
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Schistosoma mansoni hypothetical protein 0.1094 1 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.011 0.0886 0.1378
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0034 0.0034
Loa Loa (eye worm) bromodomain containing protein 0.0058 0.0406 0.0712
Schistosoma mansoni methyl-cpg binding protein mbd 0.0053 0.0357 0.0357
Mycobacterium ulcerans beta-lactamase 0.011 0.0886 0.62
Loa Loa (eye worm) latrophilin receptor protein 2 0.0148 0.124 0.2175
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0061 0.0438 0.0784
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0218 0.5144
Brugia malayi Cathepsin L-like precursor 0.0018 0.0034 0.006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0026 0.0059
Brugia malayi Cathepsin L-like precursor 0.0018 0.0034 0.006
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0438 0.0768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.024 0.1545
Loa Loa (eye worm) hypothetical protein 0.0617 0.5587 0.9801
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0072 0.0223
Brugia malayi sulfakinin receptor protein 0.0061 0.0438 0.0784
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0498 0.1749
Echinococcus granulosus somatostatin receptor 0.0061 0.0438 0.0438
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0072 0.0098
Onchocerca volvulus 0.0018 0.0034 0.006
Brugia malayi hypothetical protein 0.0061 0.0438 0.0784
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Echinococcus granulosus fetal alzheimer antigen falz 0.007 0.0514 0.0514
Loa Loa (eye worm) melatonin receptor type 1A 0.0061 0.0438 0.0768
Echinococcus multilocularis zinc finger protein 0.0064 0.0461 0.0461
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0151 0.5843
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0916 0.1425
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0916 0.0916
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0127 0.0421
Schistosoma mansoni hypothetical protein 0.0061 0.0438 0.0438
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0151 0.1628
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0916 0.0916
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0051 0.0065
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.1024 0.1595
Loa Loa (eye worm) cysteine protease 0.0018 0.0034 0.0059
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0061 0.0438 0.0438
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0072 0.0227
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0324 0.0324
Echinococcus granulosus peptide allatostatin:somatostatin 0.0061 0.0438 0.0438
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.1233 0.1233
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.0908 0.8706
Entamoeba histolytica hypothetical protein 0.0048 0.0311 0.3348
Plasmodium falciparum glutathione reductase 0.0017 0.0026 0.0408
Mycobacterium tuberculosis Conserved protein 0.011 0.0886 0.1378
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0072 0.033
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.1758 0.3084
Trypanosoma cruzi ISWI complex protein 0.0047 0.0306 0.1063
Schistosoma mansoni opsin-like receptor 0.0061 0.0438 0.0438
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0028 0.0127 0.0727
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Onchocerca volvulus 0.0061 0.0438 0.0784
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0318 0.3514
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0061 0.0438 0.0438
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0438 0.0438
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0034 0.0588
Echinococcus multilocularis geminin 0.1094 1 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.1024 0.1595
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0498 0.1752
Plasmodium falciparum importin beta, putative 0.0059 0.0415 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.001 0.001
Brugia malayi follicle stimulating hormone receptor 0.0285 0.2509 0.4492
Brugia malayi neuropeptide F receptor 0.0061 0.0438 0.0784
Echinococcus granulosus GPCR family 2 0.0148 0.124 0.124
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0151 0.075
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0074 0.0074
Onchocerca volvulus 0.0061 0.0438 0.0784
Brugia malayi RNA binding protein 0.0343 0.3044 0.5449
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0072 0.0072
Echinococcus multilocularis allatostatin A receptor 0.0061 0.0438 0.0438
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.1233 0.1233
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.024 0.0827
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Brugia malayi neuropeptide F receptor 0.0061 0.0438 0.0784
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0218 0.2345
Loa Loa (eye worm) hypothetical protein 0.0018 0.0034 0.0059
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0311 0.1542
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0061 0.0438 0.0438
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0034 0.0588
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0318 0.3514
Onchocerca volvulus 0.0018 0.0034 0.006
Schistosoma mansoni amine GPCR 0.0061 0.0438 0.0438
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0072 0.0126
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0026 0.0059
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0438 0.0438
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0026 0.0026
Echinococcus granulosus biogenic amine 5HT receptor 0.0061 0.0438 0.0438
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0026 0.0047
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.001 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0139 0.0139
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0311 0.1542
Schistosoma mansoni tar DNA-binding protein 0.0343 0.3044 0.3044
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0072 0.0357
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0062 0.0256
Brugia malayi phosphofructokinase 0.0113 0.0916 0.164
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0026 0.0059
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0498 0.1749
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0026 0.0189
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0148 0.124 0.124
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0148 0.124 0.124
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0311 0.1542
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.1024 0.1595
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0061 0.0438 0.0784
Brugia malayi hypothetical protein 0.0049 0.0326 0.0584
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0051 0.0065
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0438 0.0438
Brugia malayi putative neuropeptide receptor NPR1 0.0061 0.0438 0.0784
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0326 0.1135
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0916 0.4537
Brugia malayi beta-lactamase family protein 0.011 0.0886 0.1586
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0034 0.0166
Leishmania major cathepsin L-like protease 0.0068 0.0498 0.1749
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Brugia malayi Cathepsin L-like precursor 0.0018 0.0034 0.006
Echinococcus multilocularis serotonin receptor 0.0061 0.0438 0.0438
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0061 0.0438 0.0438
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.015 0.1256 0.4468
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.024 0.024
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0151 0.075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0498 0.1752
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0072 0.0072
Mycobacterium tuberculosis Conserved protein 0.011 0.0886 0.1378
Schistosoma mansoni hypothetical protein 0.032 0.2831 0.2831
Schistosoma mansoni opsin-like receptor 0.0061 0.0438 0.0438
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0151 1
Brugia malayi hypothetical protein 0.0061 0.0438 0.0784
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0026 0.0059
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0028 0.0127 0.0727
Loa Loa (eye worm) hypothetical protein 0.0059 0.0415 0.0727
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.0326 0.1138
Brugia malayi Cathepsin L-like precursor 0.0018 0.0034 0.006
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0916 0.0916
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.024 1
Onchocerca volvulus 0.0018 0.0034 0.006
Echinococcus multilocularis sex peptide receptor 0.0061 0.0438 0.0438
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0034 0.0059
Echinococcus multilocularis neuropeptide s receptor 0.0061 0.0438 0.0438
Schistosoma mansoni amine GPCR 0.0061 0.0438 0.0438
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0331 0.2933 0.5145
Onchocerca volvulus 0.0061 0.0438 0.0784
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0324 0.0494
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.001 0.0003
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0072 0.0129
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0061 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Plasmodium vivax vivapain-2 0.0018 0.0034 0.0272
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0108
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0438 0.0438
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0034 0.0059
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0061 0.0438 0.0768
Loa Loa (eye worm) hypothetical protein 0.0129 0.1067 0.1871
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0072 0.033
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0078 0.0078
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0034 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0438 0.0438
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0438 0.0438
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.024 0.2406
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0318 0.1573
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0218 0.8956
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0438 0.0438
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0498 0.1752
Echinococcus multilocularis tar DNA binding protein 0.0343 0.3044 0.3044
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.024 0.024
Brugia malayi hypothetical protein 0.0617 0.5587 1
Loa Loa (eye worm) TYRA-2 protein 0.0061 0.0438 0.0768
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0438 0.0438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0072 0.0129
Mycobacterium tuberculosis Probable lipase LipE 0.011 0.0886 0.1378
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Brugia malayi latrophilin 2 splice variant baaae 0.032 0.2831 0.5067
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0438 0.0438
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0151 0.1617
Loa Loa (eye worm) hypothetical protein 0.0468 0.4202 0.7372
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0034 0.0166
Loa Loa (eye worm) hypothetical protein 0.011 0.0886 0.1554
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0074 0.0074
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0916 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0127 0.0185
Loa Loa (eye worm) hypothetical protein 0.0061 0.0438 0.0768
Plasmodium vivax glutathione reductase, putative 0.0049 0.0324 0.3588
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0072 0.0227
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0148 0.124 0.124
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.0886 0.314
Loa Loa (eye worm) hypothetical protein 0.0028 0.0127 0.0223
Schistosoma mansoni neuropeptide receptor 0.0061 0.0438 0.0438

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) > 100 ug ml-1 Antibacterial activity against Escherichia coli after 16 hrs ChEMBL. 18678500
MIC (functional) > 100 ug ml-1 Antifungal activity against Saccharomyces cerevisiae after 16 hrs ChEMBL. 18678500

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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