Detailed information for compound 997866

Basic information

Technical information
  • TDR Targets ID: 997866
  • Name: (E)-3-(4-chlorophenyl)-1-(4-imidazol-1-ylphen yl)prop-2-en-1-one
  • MW: 308.762 | Formula: C18H13ClN2O
  • H donors: 0 H acceptors: 2 LogP: 4.07 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)/C=C/C(=O)c1ccc(cc1)n1cncc1
  • InChi: 1S/C18H13ClN2O/c19-16-6-1-14(2-7-16)3-10-18(22)15-4-8-17(9-5-15)21-12-11-20-13-21/h1-13H/b10-3+
  • InChiKey: LRMWPYOOJIAFIL-XCVCLJGOSA-N  

Network

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Synonyms

  • (E)-3-(4-chlorophenyl)-1-[4-(1-imidazolyl)phenyl]prop-2-en-1-one

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0289 0.2916 0.6112
Trichomonas vaginalis steroid dehydrogenase, putative 0.0027 0.0069 0.0092
Brugia malayi bHLH-PAS transcription factor 0.0144 0.1341 0.1341
Echinococcus granulosus steroid dehydrogenase 0.0027 0.0069 0.0092
Loa Loa (eye worm) hypothetical protein 0.0247 0.246 0.246
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0069 0.0092
Trichomonas vaginalis guanylate cyclase, putative 0.005 0.0328 0.0437
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0069 0.0092
Schistosoma mansoni single-minded 0.0194 0.1889 0.252
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0027 0.0069 0.0128
Leishmania major quinonoid dihydropteridine reductase 0.0027 0.0069 0.0092
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Schistosoma mansoni retinal dehydrogenase 0.0027 0.0069 0.0092
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0074 0.0584 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0289 0.2916 0.6112
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Toxoplasma gondii hypothetical protein 0.0057 0.0402 0.0671
Loa Loa (eye worm) follicle stimulating hormone receptor 0.094 1 1
Schistosoma mansoni ap endonuclease 0.0056 0.0387 0.0517
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.01 0.0867 0.1156
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Plasmodium falciparum ubiquitin specific protease, putative 0.0057 0.0402 0.1514
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0584 0.0779
Onchocerca volvulus 0.005 0.0328 0.049
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0057 0.0402 0.0536
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0057 0.0402 0.0536
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0387 0.6434
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0057 0.0402 0.0536
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.005 0.0328 0.0328
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trichomonas vaginalis ubiquitin specific protease, putative 0.0057 0.0402 0.0537
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Toxoplasma gondii ubiquitin-specific protease USP4 0.0057 0.0402 0.0671
Echinococcus granulosus caspase 3 0.0435 0.4511 0.601
Schistosoma mansoni steroid dehydrogenase 0.0027 0.0069 0.0092
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0128
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0237 0.2353 0.492
Entamoeba histolytica hypothetical protein 0.0023 0.0032 0.0043
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0584 0.0779
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0241 0.2397 0.3194
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0195 0.1897 0.1897
Echinococcus granulosus carbonyl reductase 1 0.0027 0.0069 0.0092
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.005 0.0328 0.0436
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Plasmodium vivax hypothetical protein, conserved 0.0265 0.2658 1
Schistosoma mansoni aldehyde dehydrogenase 0.0241 0.2397 0.3198
Echinococcus multilocularis lamin dm0 0.0195 0.1897 0.2527
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0057 0.0402 0.1514
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0032 0.0121
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0027 0.0069 0.0128
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0679 0.0904
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0057 0.0402 0.0537
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0027 0.0069 0.0092
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0027 0.0069 0.0092
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Leishmania major quinonoid dihydropteridine reductase 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0057 0.0402 0.0537
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Brugia malayi Retinol dehydrogenase 12 0.0027 0.0069 0.0069
Leishmania major hypothetical protein, conserved 0.0027 0.0069 0.0092
Mycobacterium tuberculosis Probable oxidoreductase 0.0027 0.0069 0.0128
Toxoplasma gondii oxidoreductase, putative 0.0027 0.0069 0.0115
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0057 0.0402 0.1514
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0057 0.0402 0.0537
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.071 0.7496 0.7496
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0027 0.0069 0.0092
Loa Loa (eye worm) hypothetical protein 0.0094 0.0801 0.0801
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0057 0.0402 0.0536
Toxoplasma gondii cytochrome p450 superfamily protein 0.0289 0.2916 0.4859
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0057 0.0402 0.141
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0402
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.071 0.7496 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0572 0.6001 0.6001
Brugia malayi hypoxia-induced factor 1 0.0601 0.631 0.631
Loa Loa (eye worm) oxidoreductase 0.0027 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0057 0.0402 0.0537
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Mycobacterium ulcerans dehydrogenase 0.0027 0.0069 0.0079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.0265 0.2658 0.2658
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Schistosoma mansoni intermediate filament proteins 0.0195 0.1897 0.2531
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.071 0.7496 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0074 0.0584 0.0973
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus granulosus caspase 0.07 0.739 0.9845
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Schistosoma mansoni peptidase 0.0063 0.0459 0.0612
Loa Loa (eye worm) oxidoreductase 0.0027 0.0069 0.0069
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0057 0.0402 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Brugia malayi hypothetical protein 0.0711 0.7506 0.7506
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.021 0.2063 0.2063
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Echinococcus multilocularis ubiquitin specific protease 41 0.071 0.7496 0.9987
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0027 0.0069 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.2658 0.3545
Onchocerca volvulus 0.0195 0.1897 0.3469
Onchocerca volvulus 0.0144 0.1341 0.2413
Loa Loa (eye worm) cytochrome P450 family protein 0.0457 0.475 0.475
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0505 0.0673
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.005 0.0328 0.0328
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0027 0.0069 0.0092
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Echinococcus granulosus single minded 2 0.0144 0.1341 0.1786
Brugia malayi hypothetical protein 0.0651 0.6858 0.6858
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0265 0.2658 0.3545
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0387 0.0517
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Schistosoma mansoni inositol monophosphatase 0.0074 0.0584 0.0779
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0679 0.0679
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0057 0.0402 0.0536
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0057 0.0402 0.141
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Loa Loa (eye worm) cytochrome P450 family protein 0.0457 0.475 0.475
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.2658 0.3545
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0671
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.005 0.0328 0.0437
Mycobacterium ulcerans short-chain dehydrogenase 0.0027 0.0069 0.0079
Leishmania major quinonoid dihydropteridine reductase 0.0027 0.0069 0.0092
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.0651 0.6858 0.6858
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.2658 0.3545
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0572 0.6001 0.8005
Schistosoma mansoni steroid dehydrogenase 0.0027 0.0069 0.0092
Plasmodium vivax steroid dehydrogenase, putative 0.0027 0.0069 0.0141
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Plasmodium vivax metacaspase 1, putative 0.0265 0.2658 1
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0402
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0289 0.2916 1
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0027 0.0069 0.0092
Loa Loa (eye worm) hypothetical protein 0.071 0.7496 0.7496
Schistosoma mansoni lamin 0.0195 0.1897 0.2531
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0057 0.0402 0.0536
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0387 0.0517
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Loa Loa (eye worm) dehydrogenase 0.0027 0.0069 0.0069
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0057 0.0402 0.0536
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0387 0.0517
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.005 0.0328 0.0437
Mycobacterium ulcerans short-chain dehydrogenase 0.0027 0.0069 0.0079
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0069
Plasmodium falciparum ubiquitin specific protease, putative 0.0057 0.0402 0.1514
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0289 0.2916 1
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.1514
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.005 0.0328 0.0437
Leishmania major hypothetical protein, conserved 0.0027 0.0069 0.0092
Entamoeba histolytica short chain dehydrogenase family protein 0.0027 0.0069 0.0092
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0115
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0069
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0027 0.0069 0.0079
Schistosoma mansoni aldehyde dehydrogenase 0.0241 0.2397 0.3198
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0069
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0069 0.0092
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0027 0.0069 0.0092
Trypanosoma cruzi metacaspase 5, putative 0.0265 0.2658 0.3545
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0289 0.2916 1
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0057 0.0402 0.0536
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0027 0.0069 0.0128
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0289 0.2916 0.6112
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.005 0.0328 0.0436
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0067 0.0505 0.0673
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.005 0.0328 0.0437
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0057 0.0402 0.0671
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0079
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0289 0.2916 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Echinococcus granulosus cytochrome P450 2K1 0.0289 0.2916 0.3885
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0027 0.0069 0.0092
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0027 0.0069 0.0092
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Brugia malayi ubiquitin specific protease 14 0.0057 0.0402 0.0402
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0027 0.0069 0.0092
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypoxia-induced factor 1 0.0601 0.631 0.631
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Possible oxidoreductase 0.0027 0.0069 0.0128
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0057 0.0402 0.0536
Echinococcus multilocularis caspase 8 0.0265 0.2658 0.3541
Leishmania major hypothetical protein, conserved 0.0027 0.0069 0.0092
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0057 0.0402 0.0537
Echinococcus multilocularis lamin 0.0195 0.1897 0.2527
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0289 0.2916 0.6112
Leishmania major short chain dehydrogenase, putative 0.0027 0.0069 0.0092
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.071 0.7496 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Brugia malayi PAS domain containing protein 0.0194 0.1889 0.1889
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0027 0.0069 0.0092
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0057 0.0402 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0057 0.0402 0.0402
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0572 0.6001 0.8005
Schistosoma mansoni caspase-3 (C14 family) 0.07 0.739 0.9858
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0671
Brugia malayi dehydrogenases, short chain protein 9 0.0027 0.0069 0.0069
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.07 0.739 0.9845
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0289 0.2916 0.6112
Trichomonas vaginalis CMGC family protein kinase 0.0572 0.6001 0.8005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0265 0.2658 0.3545
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0027 0.0069 0.0128
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0027 0.0069 0.0092
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0056 0.0384 0.0512
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0074 0.0584 0.0779
Mycobacterium tuberculosis Probable oxidoreductase 0.0027 0.0069 0.0128
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Brugia malayi hypothetical protein 0.0027 0.0069 0.0069
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0057 0.0402 0.0536
Echinococcus multilocularis caspase 0.07 0.739 0.9845
Toxoplasma gondii oxidoreductase, putative 0.0027 0.0069 0.0115
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Mycobacterium leprae Probable oxidoreductase 0.0027 0.0069 0.0128
Schistosoma mansoni steroid dehydrogenase 0.0027 0.0069 0.0092
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0057 0.0402 0.0537
Mycobacterium ulcerans oxidoreductase 0.0027 0.0069 0.0079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0027 0.0069 0.0128
Loa Loa (eye worm) dehydrogenase 0.0027 0.0069 0.0069
Leishmania major short chain dehydrogenase-like protein 0.0027 0.0069 0.0092
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0289 0.2916 0.6112
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0387 0.0517
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0289 0.2916 0.6112
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.071 0.7496 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Schistosoma mansoni serine/threonine protein kinase 0.0572 0.6001 0.8005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.2658 0.3545
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0027 0.0069 0.0128
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) oxidoreductase 0.0027 0.0069 0.0069
Schistosoma mansoni lamin 0.0195 0.1897 0.2531
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus multilocularis caspase 3 0.0435 0.4511 0.601
Trichomonas vaginalis ubiquitin specific protease, putative 0.0057 0.0402 0.0537
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0671
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Probable dehydrogenase 0.0027 0.0069 0.0128
Echinococcus multilocularis apoptotic protease activating factor 1 0.0247 0.246 0.3277
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Brugia malayi intermediate filament protein 0.0195 0.1897 0.1897
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0237 0.2353 0.8049
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0289 0.2916 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0128
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0265 0.2658 0.2658
Trichomonas vaginalis ubiquitin specific protease, putative 0.0057 0.0402 0.0537
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.071 0.7496 0.9987
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.071 0.7496 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0057 0.0402 0.0537
Mycobacterium leprae Possible regulatory protein 0.005 0.0328 0.1024
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Leishmania major 3-keto-dihydrosphingosine reductase 0.0027 0.0069 0.0092
Mycobacterium ulcerans ketoacyl reductase 0.0027 0.0069 0.0079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus granulosus caspase 2 0.0511 0.5338 0.7112
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0328 0.0437
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0265 0.2658 0.3545
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Echinococcus granulosus caspase 8 0.0265 0.2658 0.3541
Brugia malayi Inositol-1 0.0074 0.0584 0.0584
Toxoplasma gondii aldehyde dehydrogenase 0.0241 0.2397 0.3995
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0027 0.0069 0.0092
Leishmania major cytochrome p450-like protein 0.0289 0.2916 0.389
Trichomonas vaginalis guanylate cyclase, putative 0.005 0.0328 0.0437
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0241 0.2397 0.8201
Onchocerca volvulus Cell death protein 3 homolog 0.0511 0.5338 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0057 0.0402 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0069 0.0141
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0027 0.0069 0.0115
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0289 0.2916 1
Brugia malayi Melibiase family protein 0.0067 0.0505 0.0505
Trichomonas vaginalis CMGC family protein kinase 0.0572 0.6001 0.8005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0069
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0289 0.2916 0.389
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Trypanosoma cruzi short chain dehydrogenase, putative 0.0027 0.0069 0.0092
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Schistosoma mansoni survival motor neuron protein 0.0145 0.1355 0.1808
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0289 0.2916 0.6112
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Trypanosoma brucei metacaspase MCA3 0.0265 0.2658 0.3545
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0057 0.0402 0.0536
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Onchocerca volvulus 0.0057 0.0402 0.0632
Loa Loa (eye worm) hypothetical protein 0.0711 0.7506 0.7506
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0027 0.0069 0.026
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0679 0.0905
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0387 0.1457
Loa Loa (eye worm) hypothetical protein 0.009 0.0762 0.0762
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0032 0.0043
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.141
Schistosoma mansoni steroid dehydrogenase 0.0027 0.0069 0.0092
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Trypanosoma cruzi cytochrome P450, putative 0.0457 0.475 0.6337
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0057 0.0402 0.0536
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0027 0.0069 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0289 0.2916 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0584 0.0779
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0289 0.2916 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0057 0.0402 0.0536
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0027 0.0069 0.0069
Mycobacterium ulcerans dehydrogenase/reductase 0.0027 0.0069 0.0079
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0056 0.0384 0.0512
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0265 0.2658 0.3545
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0237 0.2353 0.3135
Mycobacterium ulcerans aldehyde dehydrogenase 0.0241 0.2397 0.5013
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0867 0.1157
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0387 0.0387
Echinococcus multilocularis oxidoreductase 0.0027 0.0069 0.0092
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0027 0.0069 0.026
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0027 0.0069 0.0092
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0671
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.0511 0.5338 0.5338
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.009 0.0762 0.0762
Leishmania major quinonoid dihydropteridine reductase 0.0027 0.0069 0.0092
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0057 0.0402 0.0402
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.005 0.0328 0.0437
Leishmania major hypothetical protein, conserved 0.0027 0.0069 0.0092
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0057 0.0402 0.0536
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0074 0.0584 0.117
Brugia malayi Cytochrome P450 family protein 0.0289 0.2916 0.2916
Brugia malayi cytochrome P450 0.0289 0.2916 0.2916
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0241 0.2397 0.3198
Loa Loa (eye worm) oxidoreductase 0.0027 0.0069 0.0069
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0057 0.0402 0.0537
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0289 0.2916 0.6112
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0289 0.2916 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Trypanosoma brucei metacaspase MCA2 0.0265 0.2658 0.3545
Loa Loa (eye worm) CYP4Cod1 0.0457 0.475 0.475
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0027 0.0069 0.0092
Leishmania major quinonoid dihydropteridine reductase 0.0027 0.0069 0.0092
Trypanosoma cruzi metacaspase, putative 0.0265 0.2658 0.3545
Giardia lamblia Hypothetical protein 0.0057 0.0402 0.0537
Schistosoma mansoni aryl hydrocarbon receptor 0.0194 0.1889 0.252
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0057 0.0402 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0032 0.0054
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0671
Leishmania major cytochrome p450-like protein 0.0457 0.475 0.6337
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.1514
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0069
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trypanosoma brucei short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0289 0.2916 1
Leishmania major protein kinase, putative 0.0056 0.0384 0.0512
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Schistosoma mansoni steroid dehydrogenase 0.0027 0.0069 0.0092
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Leishmania major protein kinase, putative 0.0056 0.0384 0.0512
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0027 0.0069 0.0128
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0584 0.0779
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0057 0.0402 0.0537
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0402
Echinococcus multilocularis 0.0289 0.2916 0.3885
Echinococcus multilocularis mitogen activated protein kinase 3 0.0572 0.6001 0.7995
Echinococcus multilocularis retinol dehydrogenase 13 0.0027 0.0069 0.0092
Mycobacterium leprae putative cytochrome p450 0.0289 0.2916 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trypanosoma brucei short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0115
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0057 0.0402 0.0536
Echinococcus multilocularis caspase 2 0.0511 0.5338 0.7112
Trypanosoma brucei Metacaspase-4 0.0265 0.2658 0.3545
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0289 0.2916 1
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.07 0.739 0.9845
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0069
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0027 0.0069 0.0128
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0289 0.2916 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0387 0.0516
Trichomonas vaginalis inositol monophosphatase, putative 0.0074 0.0584 0.0779
Echinococcus multilocularis carbonyl reductase 1 0.0027 0.0069 0.0092
Trypanosoma cruzi short chain dehydrogenase, putative 0.0027 0.0069 0.0092
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Schistosoma mansoni ap endonuclease 0.0056 0.0387 0.0517
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0027 0.0069 0.0092
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0241 0.2397 0.3194
Onchocerca volvulus 0.0057 0.0402 0.0632
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Brugia malayi hypothetical protein 0.0057 0.0402 0.0402
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Brugia malayi Dehydrogenases, short chain protein 30 0.0027 0.0069 0.0069
Echinococcus granulosus WW domain containing oxidoreductase 0.0027 0.0069 0.0092
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Echinococcus granulosus intermediate filament protein 0.0195 0.1897 0.2527
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0289 0.2916 0.389
Echinococcus granulosus apoptotic protease activating factor 1 0.0247 0.246 0.3277
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0289 0.2916 0.389
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0115
Loa Loa (eye worm) inositol-1 0.0074 0.0584 0.0584
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.005 0.0328 0.0437
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0584 0.0779
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0057 0.0402 0.0537
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0057 0.0402 0.0537
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Plasmodium vivax ubiquitin specific protease, putative 0.0057 0.0402 0.141
Brugia malayi hypothetical protein 0.0027 0.0069 0.0069
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0057 0.0402 0.0402
Plasmodium falciparum steroid dehydrogenase, putative 0.0027 0.0069 0.026
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0079
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0057 0.0402 0.0537
Loa Loa (eye worm) oxidoreductase 0.0027 0.0069 0.0069
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0079
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0027 0.0069 0.0092
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0289 0.2916 0.6112
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.005 0.0328 0.0437
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0057 0.0402 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.071 0.7496 0.9987
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0027 0.0069 0.0115
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0289 0.2916 0.6112
Entamoeba histolytica hypothetical protein 0.0057 0.0402 0.0537
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0027 0.0069 0.0092
Trypanosoma cruzi metacaspase 5, putative 0.0265 0.2658 0.3545
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0027 0.0069 0.0128
Loa Loa (eye worm) hypothetical protein 0.0191 0.1858 0.1858
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.0169 0.1613 0.1613
Leishmania major oxidoreductase-like protein 0.0027 0.0069 0.0092
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0387 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0057 0.0402 0.0536
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Schistosoma mansoni caspase-7 (C14 family) 0.07 0.739 0.9858
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0104 0.0914 0.0914
Trypanosoma brucei short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Trypanosoma brucei short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Schistosoma mansoni steroid dehydrogenase 0.0027 0.0069 0.0092
Echinococcus multilocularis transient receptor potential cation channel 0.0027 0.0069 0.0092
Trypanosoma brucei oxidoreductase-like protein 0.0027 0.0069 0.0092
Leishmania major dehydrogenase-like protein 0.0027 0.0069 0.0092
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0057 0.0402 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.2658 0.3545
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0027 0.0069 0.0092
Mycobacterium tuberculosis Probable oxidoreductase 0.0027 0.0069 0.0128
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Schistosoma mansoni caspase-7 (C14 family) 0.0511 0.5338 0.7121
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.071 0.7496 1
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0867 0.1157
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0671
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0057 0.0402 0.141
Echinococcus granulosus ubiquitin specific protease 41 0.071 0.7496 0.9987
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0572 0.6001 0.8005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0505 0.0505
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0289 0.2916 1
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Echinococcus multilocularis survival motor neuron protein 1 0.0711 0.7506 1
Mycobacterium ulcerans ketoacyl reductase 0.0027 0.0069 0.0079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0289 0.2916 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus multilocularis conserved hypothetical protein 0.0027 0.0069 0.0092
Leishmania major quinonoid dihydropteridine reductase 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0057 0.0402 0.0671
Echinococcus multilocularis mitogen activated protein kinase 0.0572 0.6001 0.7995
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0057 0.0402 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0328 0.0437
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0867 0.1157
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0027 0.0069 0.0092
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0572 0.6001 0.8005
Mycobacterium tuberculosis Possible oxidoreductase 0.0027 0.0069 0.0128
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0387 0.0753
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0387 0.1232
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Giardia lamblia Hypothetical protein 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0572 0.6001 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0027 0.0069 0.0092
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0057 0.0402 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans oxidoreductase 0.0027 0.0069 0.0079
Schistosoma mansoni inositol monophosphatase 0.0074 0.0584 0.0779
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0057 0.0402 0.0671
Mycobacterium ulcerans short-chain type oxidoreductase 0.0027 0.0069 0.0079
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0387 0.0517
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0057 0.0402 0.0537
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0145 0.1355 0.1355
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0057 0.0402 0.0536
Echinococcus multilocularis retinol dehydrogenase 11 0.0027 0.0069 0.0092
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0056 0.0384 0.0512
Mycobacterium ulcerans ketoacyl reductase 0.0027 0.0069 0.0079
Loa Loa (eye worm) hypothetical protein 0.0195 0.1897 0.1897
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0032 0.0043
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0387 0.0517
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.071 0.7496 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0237 0.2353 0.3139
Brugia malayi Cytochrome P450 family protein 0.0457 0.475 0.475
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0027 0.0069 0.0128
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0289 0.2916 1
Trypanosoma cruzi metacaspase, putative 0.0265 0.2658 0.3545
Trypanosoma cruzi metacaspase, putative 0.0265 0.2658 0.3545
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Schistosoma mansoni calpain-7 (C02 family) 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0128
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0265 0.2658 0.3545
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0079
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0289 0.2916 0.389
Mycobacterium leprae Conserved hypothetical protein 0.0289 0.2916 1
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Echinococcus multilocularis carbonyl reductase 1 0.0027 0.0069 0.0092
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0057 0.0402 0.0536
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.071 0.7496 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0289 0.2916 0.6112
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0115
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0289 0.2916 1
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0027 0.0069 0.0079
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0057 0.0402 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0057 0.0402 0.141
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0671
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0057 0.0402 0.0536
Toxoplasma gondii melibiase subfamily protein 0.01 0.0867 0.1446
Giardia lamblia Kinase, CMGC MAPK 0.0572 0.6001 0.8005
Mycobacterium ulcerans carveol-like dehydrogenase 0.0027 0.0069 0.0079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0387 0.0387
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0027 0.0069 0.0069
Trypanosoma brucei protein kinase, putative 0.0572 0.6001 0.8005
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0079
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0505 0.0673
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0057 0.0402 0.0536
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0128
Leishmania major quinonoid dihydropteridine reductase 0.0027 0.0069 0.0092
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Schistosoma mansoni hypothetical protein 0.0289 0.2916 0.389
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Onchocerca volvulus 0.0145 0.1355 0.2441
Echinococcus granulosus hypothetical protein 0.0027 0.0069 0.0092
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0079
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0402 0.141
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0057 0.0402 0.1514
Loa Loa (eye worm) cytochrome P450 family protein 0.0933 0.9918 0.9918
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0027 0.0069 0.0128
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.005 0.0328 1
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0289 0.2916 0.389
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0289 0.2916 0.6112
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0289 0.2916 1
Schistosoma mansoni hypothetical protein 0.0247 0.246 0.3281
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0387 0.0517
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0128
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.01 0.0867 0.1156
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0027 0.0069 0.0092
Mycobacterium tuberculosis Probable oxidoreductase 0.0027 0.0069 0.0128
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Toxoplasma gondii carbonyl reductase 1, putative 0.0027 0.0069 0.0115
Loa Loa (eye worm) oxidoreductase 0.0027 0.0069 0.0069
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0289 0.2916 0.6112
Schistosoma mansoni hypothetical protein 0.0057 0.0402 0.0537
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus multilocularis inositol monophosphatase 1 0.0074 0.0584 0.0778
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0115
Leishmania major hypothetical protein, conserved 0.0027 0.0069 0.0092
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0679 0.0904
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0265 0.2658 0.3545
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0027 0.0069 0.0092
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0057 0.0402 0.0536
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0402
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0265 0.2658 0.4428
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0069 0.0092
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Onchocerca volvulus 0.0247 0.246 0.4537
Loa Loa (eye worm) hypothetical protein 0.0083 0.0679 0.0679
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0057 0.0402 0.0536
Onchocerca volvulus 0.0083 0.0679 0.1157
Brugia malayi Cytochrome P450 family protein 0.0457 0.475 0.475
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0402
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trypanosoma cruzi metacaspase, putative 0.0265 0.2658 0.3545
Mycobacterium tuberculosis Probable oxidoreductase 0.0027 0.0069 0.0128
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0387 0.0516
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus multilocularis retinol dehydrogenase 11 0.0027 0.0069 0.0092
Loa Loa (eye worm) oxidoreductase 0.0027 0.0069 0.0069
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0027 0.0069 0.0128
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0671
Mycobacterium ulcerans short-chain dehydrogenase 0.0027 0.0069 0.0079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus multilocularis aryl hydrocarbon receptor 0.005 0.0328 0.0436
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus granulosus inositol monophosphatase 1 0.0074 0.0584 0.0778
Schistosoma mansoni steroid dehydrogenase 0.0027 0.0069 0.0092
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0128
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0265 0.2658 0.3545
Echinococcus granulosus carbonyl reductase 1 0.0027 0.0069 0.0092
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0572 0.6001 0.8005
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0027 0.0069 0.0079
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Echinococcus multilocularis musashi 0.0195 0.1897 0.2527
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.005 0.0328 0.0437
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Loa Loa (eye worm) oxidoreductase 0.0027 0.0069 0.0069
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0289 0.2916 0.6112
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0387 0.1353
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0027 0.0069 0.0092
Echinococcus multilocularis transfer RNA-Lys 0.0144 0.1341 0.1786
Loa Loa (eye worm) oxidoreductase 0.0027 0.0069 0.0069
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0027 0.0069 0.0092
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Trypanosoma brucei cytochrome P450, putative 0.0457 0.475 0.6337
Brugia malayi MAP kinase sur-1 0.0572 0.6001 0.6001
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0289 0.2916 0.6112
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0057 0.0402 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trypanosoma brucei metacaspase 0.0265 0.2658 0.3545
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0069 0.0092
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0057 0.0402 0.0536
Echinococcus granulosus survival motor neuron protein 1 0.0711 0.7506 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0237 0.2353 0.492
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0057 0.0402 0.0536
Schistosoma mansoni steroid dehydrogenase 0.0027 0.0069 0.0092
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0402
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0027 0.0069 0.0092
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.141
Trichomonas vaginalis adenylate cyclase, putative 0.005 0.0328 0.0437
Onchocerca volvulus 0.0195 0.1897 0.3469
Echinococcus granulosus aryl hydrocarbon receptor 0.005 0.0328 0.0436
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0069 0.0092
Brugia malayi Cell death protein 3 precursor 0.0511 0.5338 0.5338
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0289 0.2916 1
Echinococcus multilocularis steroid dehydrogenase 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus granulosus lamin dm0 0.0195 0.1897 0.2527
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.071 0.7496 0.9987
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.071 0.7496 1
Echinococcus granulosus lamin 0.0195 0.1897 0.2527
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0265 0.2658 0.4428
Brugia malayi Intermediate filament tail domain containing protein 0.0195 0.1897 0.1897
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Schistosoma mansoni steroid dehydrogenase 0.0027 0.0069 0.0092
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0237 0.2353 0.2353
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0057 0.0402 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0328 0.0437
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0069
Echinococcus granulosus carbonyl reductase 1 0.0027 0.0069 0.0092
Toxoplasma gondii exonuclease III APE 0.0056 0.0387 0.0645
Leishmania major pteridine reductase 1 0.0027 0.0069 0.0092
Mycobacterium ulcerans aldehyde dehydrogenase 0.0241 0.2397 0.5013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0027 0.0069 0.0115
Mycobacterium ulcerans putative regulatory protein 0.0144 0.1341 0.2774
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0128
Schistosoma mansoni carbonyl reductase 0.0027 0.0069 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0027 0.0069 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.0057 0.0402 0.0402
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0265 0.2658 0.3545
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0572 0.6001 0.8005
Schistosoma mansoni carbonyl reductase 0.0027 0.0069 0.0092
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0027 0.0069 0.0128
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Onchocerca volvulus 0.0057 0.0402 0.0632
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0671
Schistosoma mansoni carbonyl reductase 0.0027 0.0069 0.0092
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0572 0.6001 0.8005
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Trichomonas vaginalis CMGC family protein kinase 0.0572 0.6001 0.8005
Loa Loa (eye worm) intermediate filament protein 0.0195 0.1897 0.1897
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0289 0.2916 0.6112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0069
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0057 0.0402 0.0537
Echinococcus granulosus carbonyl reductase 1 0.0027 0.0069 0.0092
Entamoeba histolytica short chain dehydrogenase family protein 0.0027 0.0069 0.0092
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0057 0.0402 0.0536
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0027 0.0069 0.0092
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0402
Leishmania major metacaspase, putative 0.0265 0.2658 0.3545
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0265 0.2658 0.3545
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0057 0.0402 0.0537
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0289 0.2916 0.6112
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0237 0.2353 0.3139
Brugia malayi dehydrogenases, short chain protein 2 0.0027 0.0069 0.0069
Giardia lamblia DUB-1 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0265 0.2658 0.3545
Brugia malayi oxidoreductase 0.0027 0.0069 0.0069
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0057 0.0402 0.0536
Leishmania major short chain dehydrogenase/reductase, putative 0.0027 0.0069 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Trypanosoma brucei metacaspase 5, putative 0.0265 0.2658 0.3545
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0057 0.0402 0.0536
Schistosoma mansoni cytochrome P450 0.0289 0.2916 0.389
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0079
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0027 0.0069 0.0671
Echinococcus granulosus retinol dehydrogenase 11 0.0027 0.0069 0.0092
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0057 0.0402 0.0536
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0094 0.0801 0.1067
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0057 0.0402 0.0537
Schistosoma mansoni calpain-7 (C02 family) 0.0057 0.0402 0.0537
Loa Loa (eye worm) cytochrome P450 0.0289 0.2916 0.2916
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0094 0.0801 0.1067
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0027 0.0069 0.0092
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0027 0.0069 0.0079
Giardia lamblia Reductase, putative 0.0027 0.0069 0.0092
Leishmania major cytochrome p450-like protein 0.0289 0.2916 0.389
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0056 0.0384 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.2658 0.3545
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0057 0.0402 0.0537
Echinococcus granulosus oxidoreductase 0.0027 0.0069 0.0092
Echinococcus granulosus ubiquitin specific peptidase c family 0.0057 0.0402 0.0536
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0402 0.0537
Entamoeba histolytica hypothetical protein 0.0027 0.0069 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0867 0.1157
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0027 0.0069 0.0128
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0057 0.0402 0.0536
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0057 0.0402 0.0537
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0057 0.0402 0.1514
Mycobacterium ulcerans aldehyde dehydrogenase 0.0241 0.2397 0.5013
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.071 0.7496 1
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0027 0.0069 0.0128
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.071 0.7496 1
Echinococcus granulosus mitogen activated protein kinase 0.0572 0.6001 0.7995
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Leishmania major short chain dehydrogenase/reductase, putative 0.0027 0.0069 0.0092
Echinococcus granulosus mitogen activated protein kinase 3 0.0572 0.6001 0.7995
Brugia malayi Dehydrogenases, short chain protein 2 0.0027 0.0069 0.0069
Brugia malayi cytoplasmic intermediate filament protein 0.0104 0.0914 0.0914
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus granulosus hypothetical protein 0.0027 0.0069 0.0092
Echinococcus multilocularis carbonyl reductase 1 0.0027 0.0069 0.0092
Echinococcus multilocularis carbonyl reductase 1 0.0027 0.0069 0.0092
Schistosoma mansoni hypothetical protein 0.0145 0.1355 0.1808
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0387 0.0517
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.05 0.1622
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0584 0.0779
Trypanosoma brucei short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0402
Brugia malayi Cytochrome P450 family protein 0.0933 0.9918 0.9918
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0457 0.475 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0057 0.0402 0.0537
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0069
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0027 0.0069 0.0092
Trichomonas vaginalis CMGC family protein kinase 0.0572 0.6001 0.8005
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0057 0.0402 0.0671
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0057 0.0402 0.0402
Mycobacterium ulcerans short-chain dehydrogenase 0.0027 0.0069 0.0079
Echinococcus granulosus retinol dehydrogenase 11 0.0027 0.0069 0.0092
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.05 0.1622
Schistosoma mansoni steroid dehydrogenase 0.0027 0.0069 0.0092
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0057 0.0402 0.0536
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0237 0.2353 0.3135
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0027 0.0069 0.0069
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0027 0.0069 0.0128
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.071 0.7496 0.9987
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Giardia lamblia Short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0027 0.0069 0.0092
Echinococcus multilocularis Glycoside hydrolase, family 27 0.01 0.0867 0.1156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Echinococcus multilocularis expressed protein 0.0057 0.0402 0.0536
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0289 0.2916 0.6112
Plasmodium falciparum metacaspase 1 0.0265 0.2658 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0289 0.2916 0.6112
Brugia malayi hypothetical protein 0.0247 0.246 0.246
Schistosoma mansoni short chain dehydrogenase 0.0027 0.0069 0.0092
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0289 0.2916 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0265 0.2658 0.4428
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0057 0.0402 0.0537
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0057 0.0402 0.141
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0289 0.2916 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0032 0.0054
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0057 0.0402 0.0536
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0057 0.0402 0.0536
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0027 0.0069 0.0092
Trypanosoma cruzi cytochrome P450, putative 0.0457 0.475 0.6337
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0069 0.0069
Mycobacterium tuberculosis Probable oxidoreductase 0.0027 0.0069 0.0128
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0069 0.0079
Echinococcus multilocularis steroid dehydrogenase 0.0027 0.0069 0.0092
Leishmania major short chain dehydrogenase, putative 0.0027 0.0069 0.0092
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0057 0.0402 0.0537
Plasmodium falciparum metacaspase-like protein 0.0265 0.2658 1
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0057 0.0402 0.0537
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0057 0.0402 0.0537

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 8.26 ug ml-1 Antimalarial activity against asexual blood stage of Plasmodium falciparum 3D7 after 48 hrs by candle jar method ChEMBL. 17977622

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23 17977622

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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