Detailed information for compound 998035

Basic information

Technical information
  • TDR Targets ID: 998035
  • Name: 1-[4-(benzoyl)piperazin-1-yl]-2-(7-methyl-1H- indol-3-yl)ethane-1,2-dione
  • MW: 375.42 | Formula: C22H21N3O3
  • H donors: 1 H acceptors: 3 LogP: 2.68 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccccc1)N1CCN(CC1)C(=O)C(=O)c1c[nH]c2c1cccc2C
  • InChi: 1S/C22H21N3O3/c1-15-6-5-9-17-18(14-23-19(15)17)20(26)22(28)25-12-10-24(11-13-25)21(27)16-7-3-2-4-8-16/h2-9,14,23H,10-13H2,1H3
  • InChiKey: GFGMHHHSHWSIIJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(7-methyl-1H-indol-3-yl)-2-[4-(oxo-phenylmethyl)-1-piperazinyl]ethane-1,2-dione
  • 1-(7-methyl-1H-indol-3-yl)-2-(4-phenylcarbonylpiperazin-1-yl)ethane-1,2-dione
  • AIDS-169547
  • AIDS169547
  • Piperazine, 1-benzoyl-4-[2-(7-methyl-1H-indol-3-yl)-1,2-dioxoethyl]-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0071 0.0204
Echinococcus multilocularis snurportin 1 0.0322 0.0588 0.0588
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Echinococcus granulosus nibrin 0.0032 0.0029 0.0038
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0025 0.0271
Brugia malayi Patched related family protein 4 0.0031 0.0028 0.0081
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0039 0.0305
Loa Loa (eye worm) acetyltransferase 0.0147 0.0251 0.0332
Brugia malayi Pre-SET motif family protein 0.0234 0.0419 0.121
Schistosoma mansoni importin beta-1 0.003 0.0025 0.0034
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0189 0.0331 0.0331
Trichomonas vaginalis chaperonin, putative 0.0025 0.0015 0.0099
Onchocerca volvulus 0.021 0.0371 0.7567
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0037 0.0039 0.0305
Plasmodium vivax SET domain protein, putative 0.0034 0.0032 0.0611
Onchocerca volvulus 0.0042 0.0049 0.0456
Mycobacterium ulcerans lipase LipD 0.0042 0.0049 0.0579
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0039 0.0218
Brugia malayi Patched related family protein 12 0.0031 0.0028 0.0081
Loa Loa (eye worm) hypothetical protein 0.0042 0.0049 0.0064
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0025 0.0015 0.0099
Leishmania major 4-coumarate:coa ligase-like protein 0.0127 0.0212 0.3572
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0037 0.0039 0.0305
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.021 0.0371 1
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0037 0.0039 0.0218
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.0099 0.0099
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0049 0.0064
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0039 0.0052
Schistosoma mansoni hypothetical protein 0.0322 0.0588 0.0776
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Brugia malayi hypothetical protein 0.0032 0.0029 0.0083
Loa Loa (eye worm) hypothetical protein 0.0042 0.0049 0.0064
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0037 0.0039 0.0568
Mycobacterium tuberculosis Conserved protein 0.0042 0.0049 0.0424
Loa Loa (eye worm) leukotriene A4 hydrolase 0.3944 0.7573 1
Entamoeba histolytica hypothetical protein 0.0189 0.0331 0.3357
Loa Loa (eye worm) hypothetical protein 0.0048 0.006 0.0079
Plasmodium falciparum T-complex protein 1 subunit beta 0.0025 0.0015 0.0129
Loa Loa (eye worm) T-complex protein 1 0.0025 0.0015 0.0019
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.0099 0.1574
Giardia lamblia Replication factor C, subunit 1 0.0032 0.0029 0.5557
Mycobacterium tuberculosis Possible penicillin-binding protein 0.027 0.0487 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0049 0.0064
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.014 0.2428
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0049 0.0424
Mycobacterium ulcerans acetyl-CoA synthetase 0.0037 0.0039 0.0305
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0039 0.0218
Schistosoma mansoni ran 0.0022 0.001 0.0013
Plasmodium vivax importin-beta 2, putative 0.003 0.0025 0.0425
Loa Loa (eye worm) hypothetical protein 0.0223 0.0396 0.0523
Loa Loa (eye worm) hypothetical protein 0.0095 0.015 0.0199
Entamoeba histolytica hypothetical protein 0.0189 0.0331 0.3357
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0095 0.015 0.355
Plasmodium vivax acetyl-CoA synthetase, putative 0.0037 0.0039 0.0808
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Brugia malayi hypothetical protein 0.0031 0.0028 0.0081
Loa Loa (eye worm) patched family protein 0.0031 0.0028 0.0037
Brugia malayi beta-lactamase family protein 0.0042 0.0049 0.014
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.021 0.0371 0.0371
Treponema pallidum DNA ligase (lig) 0.0032 0.0029 0.5
Toxoplasma gondii aminopeptidase n, putative 0.021 0.0371 1
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0037 0.0039 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0029 0.0398
Toxoplasma gondii aminopeptidase N, putative 0.021 0.0371 1
Schistosoma mansoni ran 0.0022 0.001 0.0013
Entamoeba histolytica acyl-CoA synthetase, putative 0.0127 0.0212 0.2113
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0052
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0032 0.0042
Onchocerca volvulus 0.0034 0.0032 0.0092
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.021 0.0371 0.766
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0049 0.0681
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.021 0.0371 0.638
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0049 0.0424
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0223 0.0396 0.0523
Mycobacterium ulcerans hypothetical protein 0.0166 0.0288 0.757
Echinococcus multilocularis sterol regulatory element binding protein 0.0223 0.0396 0.0396
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0251 0.0725
Schistosoma mansoni hypothetical protein 0.0172 0.0299 0.0395
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0032 0.0042
Onchocerca volvulus 0.0267 0.0482 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0037 0.0039 0.0218
Loa Loa (eye worm) hypothetical protein 0.021 0.0371 0.049
Loa Loa (eye worm) hypothetical protein 0.0037 0.0038 0.005
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.021 0.0371 0.766
Echinococcus granulosus puromycin sensitive aminopeptidase 0.021 0.0371 0.049
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0038 0.011
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0149 0.0256 0.4335
Loa Loa (eye worm) hypothetical protein 0.0095 0.015 0.0199
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.01 0.0161 0.0161
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0039 0.0619
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.014 0.2428
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.0099 0.0131
Leishmania major T-complex protein 1, beta subunit, putative 0.0025 0.0015 0.0082
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0039 0.0568
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0251 0.0332
Echinococcus multilocularis leukotriene A 4 hydrolase 0.3944 0.7573 0.7573
Plasmodium falciparum acyl-CoA synthetase 0.0095 0.015 0.3885
Echinococcus granulosus puromycin sensitive aminopeptidase 0.021 0.0371 0.049
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0025 0.0015 0.0082
Loa Loa (eye worm) hypothetical protein 0.0095 0.015 0.0199
Trichomonas vaginalis replication factor C large subunit, putative 0.0032 0.0029 0.0398
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0025 0.0015 0.0082
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0095 0.015 0.2647
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.021 0.0371 0.638
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Toxoplasma gondii hypothetical protein 0.0031 0.0028 0.0495
Trichomonas vaginalis set domain proteins, putative 0.0267 0.0482 1
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0519 0.0967 1
Brugia malayi Myosin head containing protein 0.0031 0.0028 0.0081
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.01 0.0161 0.0212
Loa Loa (eye worm) hypothetical protein 0.0054 0.0071 0.0093
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.021 0.0371 0.049
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0127 0.0212 0.028
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0049 0.108
Leishmania major importin beta-1 subunit, putative 0.0024 0.0014 0.0077
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0316 0.0576 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Schistosoma mansoni aminopeptidase A (M01 family) 0.021 0.0371 0.049
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.006 0.0079
Echinococcus multilocularis Niemann Pick C1 protein 0.0741 0.1397 0.1397
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0049 0.0818
Echinococcus granulosus puromycin sensitive aminopeptidase 0.021 0.0371 0.049
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0099 0.2054
Onchocerca volvulus 0.0127 0.0212 0.4064
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0099 0.0131
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0037 0.0039 0.0808
Echinococcus granulosus expressed conserved protein 0.0487 0.0907 0.1197
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0039 0.0305
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0037 0.0039 0.0305
Loa Loa (eye worm) patched family protein 0.0031 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0037 0.0039 0.0305
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.021 0.0371 0.638
Entamoeba histolytica hypothetical protein 0.0189 0.0331 0.3357
Trypanosoma cruzi Aminopeptidase M1, putative 0.021 0.0371 0.638
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0127 0.0212 0.5358
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.0161 0.0212
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0044 0.0353
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.021 0.0371 1
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0014 0.0092
Brugia malayi AMP-binding enzyme family protein 0.0127 0.0212 0.0613
Schistosoma mansoni topbp1 0.0032 0.0029 0.0038
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0095 0.015 1
Loa Loa (eye worm) patched family protein 0.0031 0.0028 0.0037
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.001 0.0029
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0025 0.0425
Plasmodium vivax acyl-CoA synthetase, putative 0.0095 0.015 0.3885
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0037 0.0039 0.0305
Loa Loa (eye worm) aminopeptidase N 0.021 0.0371 0.049
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0049 0.0818
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0037 0.0039 0.0305
Schistosoma mansoni topbp1 0.0032 0.0029 0.0038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.0161 0.0212
Plasmodium falciparum importin beta, putative 0.003 0.0025 0.0425
Echinococcus multilocularis protein patched 0.0223 0.0396 0.0396
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.001 0.001
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Toxoplasma gondii ABC1 family protein 0.0042 0.0049 0.1068
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0037 0.0039 0.0808
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0014 0.0092
Echinococcus multilocularis aminopeptidase N 0.021 0.0371 0.0371
Brugia malayi Pax transcription activation domain interacting protein 0.0032 0.0029 0.0083
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0127 0.0212 1
Echinococcus granulosus Protein patched homolog 1 0.0223 0.0396 0.0523
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0049 0.0681
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0025 0.0015 0.0015
Toxoplasma gondii hypothetical protein 0.0051 0.0066 0.1535
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0049 0.0424
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0037 0.0039 0.0515
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.021 0.0371 0.638
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.001 0.0013
Trypanosoma cruzi aminopeptidase, putative 0.021 0.0371 0.638
Loa Loa (eye worm) hypothetical protein 0.0127 0.0212 0.028
Brugia malayi hypothetical protein 0.0031 0.0028 0.0081
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.0029 0.0331
Schistosoma mansoni hypothetical protein 0.0215 0.0381 0.0503
Brugia malayi Peptidase family M1 containing protein 0.021 0.0371 0.1072
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.021 0.0371 0.0371
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0044 1
Loa Loa (eye worm) beta-lactamase 0.0042 0.0049 0.0064
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.021 0.0371 0.638
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0049 0.0424
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.021 0.0371 0.638
Plasmodium vivax replication factor C subunit 1, putative 0.0032 0.0029 0.0519
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0037 0.0039 0.0218
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0049 0.0424
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.3944 0.7573 1
Brugia malayi protein C24B5.3 0.0031 0.0028 0.0081
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.021 0.0371 0.049
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0039 0.0515
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0037 0.0039 0.0305
Toxoplasma gondii patched family protein 0.0031 0.0028 0.0495
Mycobacterium tuberculosis Conserved hypothetical protein 0.0166 0.0288 0.5655
Toxoplasma gondii ATPase, AAA family protein 0.0032 0.0029 0.0519
Echinococcus multilocularis protein dispatched 1 0.0254 0.0457 0.0457
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0038
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0039 0.0515
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Mycobacterium ulcerans hypothetical protein 0.0042 0.0049 0.0579
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0039 0.0113
Loa Loa (eye worm) hypothetical protein 0.0273 0.0493 0.0651
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.0161 0.0212
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0032 0.0611
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0051 0.0863
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0049 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0032 0.0042
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0189 0.0331 0.0438
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0212 0.0375 0.7652
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.0029 0.0398
Loa Loa (eye worm) hypothetical protein 0.021 0.0371 0.049
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0049 0.0064
Toxoplasma gondii t-complex protein beta subunit 0.0025 0.0015 0.0129
Leishmania major 4-coumarate:coa ligase-like protein 0.0127 0.0212 0.3572
Brugia malayi hypothetical protein 0.0031 0.0028 0.0081
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0042 0.0049 0.0064
Echinococcus granulosus puromycin sensitive aminopeptidase 0.021 0.0371 0.049
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.021 0.0371 0.766
Echinococcus granulosus Niemann Pick C1 protein 0.0519 0.0967 0.1277
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0099 0.2054
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0051 0.1127
Mycobacterium ulcerans aminopeptidase N PepN 0.021 0.0371 1
Brugia malayi topoisomerase 0.0032 0.0029 0.0083
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0032 0.0029 0.0519
Echinococcus granulosus snurportin 1 0.0322 0.0588 0.0776
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0015 0.0019
Loa Loa (eye worm) patched family protein 0.0031 0.0028 0.0037
Echinococcus granulosus Niemann Pick C1 protein 0.0741 0.1397 0.1844
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.021 0.0371 0.638
Giardia lamblia TCP-1 chaperonin subunit beta 0.0025 0.0015 0.1376
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0025 0.0271
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0037 0.0039 0.0113
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.01 0.0161 0.0464
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0039 0.0305
Loa Loa (eye worm) hypothetical protein 0.021 0.0371 0.049
Loa Loa (eye worm) hypothetical protein 0.0127 0.0212 0.028
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0051 0.0067
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0037 0.0039 0.0305
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0127 0.0212 0.4
Echinococcus multilocularis expressed conserved protein 0.0487 0.0907 0.0907
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.014 0.2428
Loa Loa (eye worm) patched family protein 0.0031 0.0028 0.0037
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.021 0.0371 0.638
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0049 0.0424
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0032 0.0029 0.0083
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0032 0.0029 0.0196
Brugia malayi AMP-binding enzyme family protein 0.0127 0.0212 0.0613
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0025 0.0015 0.0049
Plasmodium falciparum lipid/sterol:H+ symporter 0.0031 0.0028 0.0495
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.021 0.0371 0.0371
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0037 0.0039 0.0113
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.0029 0.0331
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0051 0.1127
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.01 0.0161 0.0212
Entamoeba histolytica acyl-coA synthetase, putative 0.0127 0.0212 0.2113
Echinococcus granulosus sterol regulatory element binding protein 0.0223 0.0396 0.0523
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.014 0.2428
Mycobacterium tuberculosis Conserved protein 0.0042 0.0049 0.0424
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0039 0.0113
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0014 0.0092
Echinococcus multilocularis importin subunit beta 1 0.003 0.0025 0.0025
Loa Loa (eye worm) oxidoreductase 0.0037 0.0039 0.0052
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0039 0.0515
Entamoeba histolytica hypothetical protein 0.0189 0.0331 0.3357
Plasmodium falciparum replication factor C subunit 1, putative 0.0032 0.0029 0.0519
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0037 0.0039 0.0039
Brugia malayi hypothetical protein 0.0189 0.0331 0.0957
Brugia malayi N-terminal motif family protein 0.0212 0.0375 0.1083
Brugia malayi beta-lactamase family protein 0.0042 0.0049 0.014
Brugia malayi CHE-14 protein 0.0223 0.0396 0.1144
Leishmania major hypothetical protein, conserved 0.0042 0.0049 0.0681
Entamoeba histolytica hypothetical protein 0.0024 0.0014 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0029 0.0398
Brugia malayi hypothetical protein 0.0032 0.0029 0.0083
Onchocerca volvulus 0.0037 0.0039 0.0249
Schistosoma mansoni hypothetical protein 0.0172 0.0299 0.0395
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0037 0.0039 0.0305
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.021 0.0371 0.638
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0049 0.014
Echinococcus granulosus aminopeptidase N 0.021 0.0371 0.049
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0039 0.0218
Plasmodium falciparum M1-family alanyl aminopeptidase 0.021 0.0371 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0032 0.0042
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0032 0.0032
Echinococcus multilocularis nibrin 0.0032 0.0029 0.0029
Echinococcus granulosus importin subunit beta 1 0.003 0.0025 0.0034
Toxoplasma gondii propionate-CoA ligase 0.0037 0.0039 0.0808
Schistosoma mansoni hypothetical protein 0.0189 0.0331 0.0438
Mycobacterium ulcerans acyl-CoA synthetase 0.0127 0.0212 0.5358
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0071 0.0204
Brugia malayi DKFZp564C0469 protein 0.0032 0.0029 0.0083
Mycobacterium ulcerans beta-lactamase 0.0042 0.0049 0.0579
Schistosoma mansoni DNA ligase IV 0.0032 0.0029 0.0038
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0039 0.0515
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.021 0.0371 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0051 0.0863
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0127 0.0212 0.4
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0243 0.0321
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0042 0.0049 0.0064
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.003 0.0039
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0049 0.0424
Brugia malayi protein C24B5.3 0.0031 0.0028 0.0081
Schistosoma mansoni acetyl-CoA synthetase 0.0037 0.0039 0.0052
Entamoeba histolytica hypothetical protein 0.0032 0.0029 0.0196
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0053 0.0757
Brugia malayi hypothetical protein 0.1813 0.3464 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0322 0.0588 0.0776
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.01 0.0161 0.0212
Schistosoma mansoni hypothetical protein 0.0215 0.0381 0.0503
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0072 0.1088
Echinococcus multilocularis Niemann Pick C1 protein 0.0519 0.0967 0.0967
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0256 0.4335
Mycobacterium ulcerans hypothetical protein 0.0127 0.0212 0.5358
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.0015 0.0042
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.021 0.0371 0.049
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0039 0.0305
Echinococcus multilocularis tumor protein p63 0.0327 0.0598 0.0598
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0039 0.0305
Loa Loa (eye worm) hypothetical protein 0.0095 0.015 0.0199
Schistosoma mansoni hypothetical protein 0.0037 0.0038 0.005
Schistosoma mansoni patched 1 0.0223 0.0396 0.0523
Plasmodium vivax patched family protein, putative 0.0031 0.0028 0.0495
Echinococcus granulosus puromycin sensitive aminopeptidase 0.021 0.0371 0.049
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0127 0.0212 0.5358
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0037 0.0039 0.0218
Onchocerca volvulus 0.0042 0.0049 0.0456
Onchocerca volvulus 0.021 0.0371 0.7567
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0038
Loa Loa (eye worm) peptidase family M1 containing protein 0.021 0.0371 0.049
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.001 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0029 0.0398
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0049 0.0818
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.021 0.0371 0.638
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0039 0.0515
Leishmania major mitochondrial DNA polymerase beta 0.0316 0.0576 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0071 0.0093
Brugia malayi Patched protein homolog 1 0.0031 0.0028 0.0081
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0049 0.0049
Mycobacterium ulcerans aminopeptidase N PepN 0.021 0.0371 1
Trypanosoma cruzi FHA domain containing protein, putative 0.0032 0.0029 0.0331
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.021 0.0371 0.0371
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0049 0.1068
Onchocerca volvulus 0.0037 0.0039 0.0249
Mycobacterium ulcerans acyl-CoA synthetase 0.0127 0.0212 0.5358
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0029 0.0331
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0044 0.0934
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0039 0.0305
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.01 0.0161 0.0161
Brugia malayi Pre-SET motif family protein 0.0034 0.0032 0.0093
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0049 0.0818
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0234 0.0419 0.0554
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.0099 0.2466
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.0099 0.1527
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0029 0.0398
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0039 0.0515
Brugia malayi beta-lactamase 0.0042 0.0049 0.014
Trypanosoma cruzi aminopeptidase, putative 0.021 0.0371 0.638
Entamoeba histolytica acyl-CoA synthetase, putative 0.0127 0.0212 0.2113
Mycobacterium leprae Probable lipase LipE 0.0042 0.0049 0.108
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.021 0.0371 0.0371
Schistosoma mansoni chromosome transmission fidelity factor 0.0032 0.0029 0.0038
Echinococcus granulosus geminin 0.0172 0.0299 0.0395
Trypanosoma brucei Aminopeptidase M1, putative 0.021 0.0371 0.638
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0029 0.0398
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0039 0.0113
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0049 0.0681
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Schistosoma mansoni transcription factor LCR-F1 0.0189 0.0331 0.0438
Loa Loa (eye worm) TATA binding protein associated factor 0.021 0.0371 0.049
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0039 0.0305
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0256 0.4335
Brugia malayi Patched related family protein 10 0.0031 0.0028 0.0081
Brugia malayi TATA binding protein associated factor 0.021 0.0371 0.1072
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.0095 0.015 0.0199
Brugia malayi Peptidase family M1 containing protein 0.021 0.0371 0.1072
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0015 0.0019
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0049 0.0579
Onchocerca volvulus 0.0032 0.0029 0.0019
Onchocerca volvulus 0.0042 0.0049 0.0456
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0049 0.0818
Entamoeba histolytica aminopeptidase, putative 0.021 0.0371 0.3774
Schistosoma mansoni hypothetical protein 0.0215 0.0381 0.0503
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0038
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0032 0.0029 0.5
Trypanosoma brucei Aminopeptidase M1, putative 0.021 0.0371 0.638
Brugia malayi hypothetical protein 0.021 0.0371 0.1072
Brugia malayi Niemann-Pick C1 protein precursor 0.0519 0.0967 0.2793
Schistosoma mansoni hypothetical protein 0.0215 0.0381 0.0503
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0039 0.0052
Toxoplasma gondii patched family protein 0.0031 0.0028 0.0495
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0039 0.0619
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0039 0.0515
Brugia malayi Importin beta-1 subunit 0.003 0.0025 0.0073
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0053 0.0757
Mycobacterium ulcerans acyl-CoA synthetase 0.0127 0.0212 0.5358
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0127 0.0212 0.5358
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0037 0.0039 0.0568
Trypanosoma brucei aminopeptidase, putative 0.021 0.0371 0.638
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0032 0.0042
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0527 0.0983 0.1298
Leishmania major 4-coumarate:coa ligase-like protein 0.0127 0.0212 0.3572
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0099 0.0131
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0039 0.0305
Onchocerca volvulus 0.0037 0.0039 0.0249
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0039 0.0218
Brugia malayi RNA, U transporter 1 0.0086 0.0133 0.0383
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Toxoplasma gondii patched family protein 0.0031 0.0028 0.0495
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0316 0.0576 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0014 0.0077
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.0029 0.0398
Trichomonas vaginalis esterase, putative 0.0042 0.0049 0.0818
Loa Loa (eye worm) hypothetical protein 0.0034 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0038
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0037 0.0039 0.0808
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0051 0.1127
Brugia malayi hypothetical protein 0.0031 0.0028 0.0081
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0049 0.0579
Toxoplasma gondii patched family protein 0.0031 0.0028 0.0495
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0052
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0127 0.0212 0.5358
Mycobacterium tuberculosis Conserved protein 0.0042 0.0049 0.0424
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0039 0.0113
Onchocerca volvulus 0.0048 0.006 0.0699
Loa Loa (eye worm) hypothetical protein 0.0519 0.0967 0.1277
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Brugia malayi AMP-binding enzyme family protein 0.0127 0.0212 0.0613
Onchocerca volvulus 0.021 0.0371 0.7567
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.0015 0.0042
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0316 0.0576 1
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0037 0.0039 0.0218
Echinococcus multilocularis geminin 0.0172 0.0299 0.0299
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0037 0.0039 0.0052
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0037 0.0039 0.0218
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Echinococcus granulosus puromycin sensitive aminopeptidase 0.021 0.0371 0.049
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0039 0.0515
Trichomonas vaginalis conserved hypothetical protein 0.0223 0.0396 0.8192
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.0029 0.0398
Brugia malayi Patched family protein 0.0031 0.0028 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0029 0.0331
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.003 0.0025 0.0034
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.021 0.0371 0.0371
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0053 0.0757
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0025 0.0015 0.0129
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0049 0.0064
Brugia malayi Peptidase family M1 containing protein 0.021 0.0371 0.1072
Echinococcus granulosus leukotriene A 4 hydrolase 0.3944 0.7573 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0099 0.2054
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0053 0.0757
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0127 0.0212 1
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0025 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.0212 0.0375 0.0495
Toxoplasma gondii aminopeptidase N protein 0.021 0.0371 1
Echinococcus granulosus replication factor c subunit 1 0.0032 0.0029 0.0038
Echinococcus multilocularis replication factor c subunit 1 0.0032 0.0029 0.0029
Brugia malayi hypothetical protein 0.021 0.0371 0.1072
Onchocerca volvulus 0.0037 0.0039 0.0249
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.0029 0.0398
Echinococcus granulosus tumor protein p63 0.0327 0.0598 0.079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0049 0.0064

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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