Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | peregrin | 0.0028 | 0.0906 | 0.0906 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0041 | 0.2683 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0906 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.2683 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0041 | 0.2683 | 0.2683 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0891 | 0.332 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0041 | 0.2683 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.2683 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.2683 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0093 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0364 | 0.1358 |
Echinococcus granulosus | peregrin | 0.0028 | 0.0906 | 0.0906 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0041 | 0.2683 | 0.5198 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.2683 | 1 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0906 | 0.0906 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0364 | 0.0706 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.0364 | 0.4024 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.2683 | 0.2683 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0906 | 0.1239 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0034 | 0.1747 | 0.239 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0041 | 0.2683 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.5162 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.2683 | 0.2683 |
Echinococcus granulosus | dna polymerase kappa | 0.0041 | 0.2683 | 0.2683 |
Echinococcus granulosus | dna polymerase eta | 0.0041 | 0.2683 | 0.2683 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.0364 | 0.1358 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0034 | 0.1747 | 0.239 |
Onchocerca volvulus | Alhambra homolog | 0.0028 | 0.0906 | 0.5 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0041 | 0.2683 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0041 | 0.2683 | 0.3671 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0364 | 0.1358 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0028 | 0.0906 | 0.1239 |
Trypanosoma brucei | unspecified product | 0.0028 | 0.0891 | 0.332 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0364 | 0.1358 |
Trypanosoma brucei | unspecified product | 0.0041 | 0.2683 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0906 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0.0906 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0041 | 0.2683 | 1 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0039 | 0.2471 | 0.2471 |
Giardia lamblia | PHD finger protein 15 | 0.0028 | 0.0906 | 0.3376 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.1747 | 0.1747 |
Echinococcus multilocularis | dna polymerase kappa | 0.0041 | 0.2683 | 0.2683 |
Leishmania major | DNA polymerase eta, putative | 0.0041 | 0.2683 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0891 | 0.332 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0028 | 0.0906 | 0.0906 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0906 | 0.1755 |
Giardia lamblia | DINP protein human, muc B family | 0.0041 | 0.2683 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0041 | 0.2683 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.0039 | 0.2471 | 0.2471 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0028 | 0.0906 | 0.0906 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.2683 | 0.5198 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0034 | 0.1747 | 0.3384 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.3761 | 0.7287 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.0364 | 0.4024 |
Trypanosoma brucei | unspecified product | 0.0028 | 0.0891 | 0.332 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0028 | 0.0906 | 0.1755 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0034 | 0.1747 | 0.1747 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0093 | 1 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0034 | 0.1747 | 0.1747 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0041 | 0.2683 | 0.2683 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.2683 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0891 | 0.332 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0041 | 0.2683 | 0.3671 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0041 | 0.2683 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0364 | 0.4024 |
Brugia malayi | Bromodomain containing protein | 0.0028 | 0.0906 | 0.0906 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0041 | 0.2683 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.0028 | 0.0906 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.2683 | 1 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0364 | 0.0364 |
Schistosoma mansoni | jumonji domain containing protein | 0.0074 | 0.7309 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0364 | 0.4024 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0041 | 0.2683 | 0.2683 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0041 | 0.2683 | 0.3671 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.