Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.2536 | 0.2751 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0309 | 1 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0031 | 0.0485 | 0.1914 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.02 | 0.0294 |
Brugia malayi | hypothetical protein | 0.0117 | 0.3438 | 0.366 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0139 | 0.4186 | 1 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.2536 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.1629 | 0.3739 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0602 | 0.0548 |
Onchocerca volvulus | 0.0035 | 0.0602 | 0.0462 | |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0102 | 0.0107 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0603 | 0.065 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.02 | 0.0294 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0091 | 0.2536 | 1 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0106 | 0.3043 | 0.72 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0107 | 0.3065 | 0.6147 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0034 | 0.0558 | 0.1116 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0139 | 0.4186 | 0.4539 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.2536 | 0.2751 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0139 | 0.4186 | 0.4541 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0091 | 0.2536 | 0.5959 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0167 | 0.513 | 0.5678 |
Loa Loa (eye worm) | phosphofructokinase | 0.0106 | 0.3043 | 0.3301 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0056 | 0.1345 | 0.1363 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.3043 | 0.3226 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0602 | 0.0653 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.02 | 0.0217 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.1345 | 0.3043 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.1629 | 0.1767 |
Leishmania major | trypanothione reductase | 0.0047 | 0.1011 | 0.0918 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0106 | 0.3043 | 0.2971 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.006 | 0.1458 | 0.332 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.039 | 0.0315 |
Entamoeba histolytica | hypothetical protein | 0.0117 | 0.3438 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.1345 | 0.1459 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.039 | 0.1536 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 0.813 | 0.8806 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.02 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0102 | 0.0111 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.513 | 0.5516 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.1629 | 0.1764 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0029 | 0.039 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.2536 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0117 | 0.3438 | 0.3727 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0146 | 0.4421 | 0.4363 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0118 | 0.3474 | 0.6966 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.1156 | 0.1254 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.5439 | 0.5854 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.1011 | 0.3987 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.02 | 0.0099 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.1629 | 0.3739 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.02 | 0.0217 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.513 | 0.5516 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.1345 | 0.3043 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.039 | 0.0315 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0146 | 0.4421 | 0.4363 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.1156 | 0.1156 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0102 | 0.0111 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0043 | 0.0897 | 0.0803 |
Onchocerca volvulus | Huntingtin homolog | 0.0131 | 0.3914 | 0.4277 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0602 | 0.0649 |
Entamoeba histolytica | hypothetical protein | 0.0117 | 0.3438 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.02 | 0.0217 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.1629 | 0.1767 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0897 | 0.0803 |
Brugia malayi | RNA binding protein | 0.0065 | 0.1629 | 0.1675 |
Brugia malayi | glutaminase DH11.1 | 0.0286 | 0.9218 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0139 | 0.4186 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.02 | 0.0402 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0602 | 0.0649 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.039 | 0.1536 |
Brugia malayi | glutathione reductase | 0.0047 | 0.1011 | 0.0997 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0031 | 0.0485 | 0.0871 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.02 | 0.0217 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0031 | 0.0485 | 0.0361 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.3914 | 0.4246 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.02 | 0.0217 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0118 | 0.3474 | 0.6966 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0053 | 0.1215 | 0.1318 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0029 | 0.039 | 0.0315 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.2536 | 1 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0106 | 0.3043 | 0.72 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.02 | 0.0217 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0056 | 0.1345 | 0.1256 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0602 | 0.0649 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.2536 | 0.809 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0163 | 0.4987 | 1 |
Plasmodium vivax | sortilin, putative | 0.0071 | 0.1841 | 0.7258 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0106 | 0.3043 | 0.8683 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.1345 | 0.1459 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.006 | 0.1458 | 0.3843 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.3914 | 0.4246 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0146 | 0.4421 | 0.4363 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.1156 | 0.1156 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.3043 | 0.3226 |
Echinococcus granulosus | peptidase Clp S14 family | 0.006 | 0.1458 | 0.332 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0031 | 0.0485 | 0.1914 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0106 | 0.3043 | 0.3298 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0309 | 1 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.1011 | 0.2028 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0107 | 0.3065 | 0.6147 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 0.813 | 0.8806 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0603 | 0.0549 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0107 | 0.3065 | 0.8753 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 0.813 | 0.8806 |
Toxoplasma gondii | sortilin, putative | 0.0071 | 0.1841 | 0.676 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0091 | 0.2536 | 1 |
Brugia malayi | phosphofructokinase | 0.0106 | 0.3043 | 0.3226 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.02 | 0.0217 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0106 | 0.3043 | 0.3301 |
Echinococcus granulosus | sortilin | 0.0071 | 0.1841 | 0.4256 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0603 | 0.0654 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0091 | 0.2536 | 0.7135 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0091 | 0.2536 | 0.5959 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.1011 | 0.1097 |
Brugia malayi | Probable ClpP-like protease | 0.0091 | 0.2536 | 0.267 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.02 | 0.0217 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0053 | 0.1223 | 0.1132 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.1011 | 0.3987 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0118 | 0.3474 | 0.6966 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0139 | 0.4186 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0117 | 0.0123 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0117 | 0.3438 | 0.8169 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.1629 | 0.1675 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0118 | 0.3474 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0139 | 0.4186 | 0.4539 |
Schistosoma mansoni | glutaminase | 0.0286 | 0.9218 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0106 | 0.3043 | 0.8814 |
Mycobacterium ulcerans | hypothetical protein | 0.0163 | 0.4987 | 0.541 |
Entamoeba histolytica | hypothetical protein | 0.0117 | 0.3438 | 1 |
Onchocerca volvulus | 0.0276 | 0.8884 | 1 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0309 | 1 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.1011 | 0.1097 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0106 | 0.3043 | 0.8814 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.513 | 0.5516 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0254 | 0.813 | 0.8819 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 0.813 | 0.8806 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.1629 | 0.1764 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.1629 | 0.1675 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0107 | 0.3065 | 0.6147 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.1629 | 0.1764 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.02 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1156 | 0.1254 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0254 | 0.813 | 0.8806 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0102 | 0.0111 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0139 | 0.4186 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.513 | 0.5516 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.039 | 0.1536 |
Mycobacterium tuberculosis | Probable reductase | 0.0107 | 0.3065 | 0.6147 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0102 | 0.0107 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.1011 | 0.0918 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0035 | 0.0602 | 0.1223 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0106 | 0.3043 | 0.2971 |
Brugia malayi | hypothetical protein | 0.0131 | 0.3914 | 0.4182 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0602 | 0.2373 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0106 | 0.3043 | 0.8814 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0107 | 0.3065 | 0.6147 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.513 | 0.5516 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.3043 | 0.3226 |
Entamoeba histolytica | hypothetical protein | 0.0117 | 0.3438 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 0.813 | 0.8806 |
Echinococcus multilocularis | sortilin | 0.0071 | 0.1841 | 0.4256 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0602 | 0.1223 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.039 | 0.1536 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0897 | 0.0803 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.02 | 0.0402 |
Onchocerca volvulus | Huntingtin homolog | 0.0131 | 0.3914 | 0.4277 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0102 | 0.0205 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.02 | 0.0294 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.02 | 0.0108 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.1011 | 0.0997 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0102 | 0.0205 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 0.813 | 0.8806 |
Brugia malayi | 6-phosphofructokinase | 0.0106 | 0.3043 | 0.3226 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.006 | 0.1458 | 0.2924 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.1011 | 0.2896 |
Toxoplasma gondii | hypothetical protein | 0.005 | 0.1116 | 0.3384 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0139 | 0.4186 | 0.4539 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.1011 | 0.3987 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0106 | 0.3043 | 0.3301 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.02 | 0.0108 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.039 | 0.1536 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.039 | 0.0315 |
Loa Loa (eye worm) | glutaminase 2 | 0.0286 | 0.9218 | 1 |
Trichomonas vaginalis | glutaminase, putative | 0.0286 | 0.9218 | 1 |
Loa Loa (eye worm) | glutaminase | 0.0286 | 0.9218 | 1 |
Mycobacterium ulcerans | glutaminase | 0.0286 | 0.9218 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.0602 | 0.1223 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.006 | 0.1458 | 0.2924 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.1629 | 0.1764 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0091 | 0.2536 | 0.2748 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0243 | 0.7733 | 0.8389 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0029 | 0.039 | 0.0861 |
Brugia malayi | 6-phosphofructokinase | 0.0106 | 0.3043 | 0.3226 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.2536 | 0.5 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0106 | 0.3043 | 0.2971 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0102 | 0.0107 |
Trichomonas vaginalis | set domain proteins, putative | 0.0276 | 0.8884 | 0.9633 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.02 | 0.0108 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0117 | 0.3438 | 0.8169 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0602 | 0.0649 |
Schistosoma mansoni | sortilin | 0.005 | 0.1131 | 0.1223 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0091 | 0.2536 | 1 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0106 | 0.3043 | 0.3301 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0106 | 0.3043 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.1011 | 0.0918 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.0602 | 0.0988 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.3043 | 0.3226 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0106 | 0.3043 | 0.3298 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.1629 | 0.1767 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0139 | 0.4186 | 0.448 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.1629 | 0.1764 |
Brugia malayi | Pre-SET motif family protein | 0.0243 | 0.7733 | 0.8371 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.039 | 0.0315 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 0.1345 | 0.2697 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.1011 | 0.2225 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0117 | 0.3438 | 0.3727 |
Plasmodium falciparum | sortilin | 0.0071 | 0.1841 | 0.7258 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0102 | 0.0111 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.5439 | 0.5854 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.2536 | 0.2751 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.1011 | 0.3987 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.02 | 0.0099 |
Toxoplasma gondii | hypothetical protein | 0.0031 | 0.0485 | 0.0446 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.039 | 0.0315 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0106 | 0.3043 | 0.6101 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.02 | 0.0217 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.513 | 0.5516 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.513 | 0.5516 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.039 | 0.0315 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.1011 | 0.2225 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0056 | 0.1345 | 0.1455 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0043 | 0.0897 | 0.0803 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.02 | 0.0217 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0107 | 0.3065 | 0.6147 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.039 | 0.1536 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.