Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.1542 | 1 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.008 | 0.0079 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0047 | 0.0214 | 0.0213 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0037 | 0.0035 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0018 | 0.0017 |
Brugia malayi | NADH-dependent xylose reductase | 0.0447 | 0.2831 | 0.2831 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0447 | 0.2831 | 0.2818 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0037 | 0.0035 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.1542 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.1542 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0037 | 0.0035 |
Brugia malayi | cytochrome P450 | 0.0014 | 0.0001 | 0.0001 |
Echinococcus multilocularis | geminin | 0.0166 | 0.0996 | 0.0994 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0037 | 0.0037 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0447 | 0.2831 | 0.283 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0904 | 0.5828 | 0.5828 |
Loa Loa (eye worm) | hypothetical protein | 0.1542 | 1 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0008 | 0.0007 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0496 | 0.0495 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0447 | 0.2831 | 0.2818 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.006 | 0.0058 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0037 | 0.0035 |
Onchocerca volvulus | 0.1542 | 1 | 1 | |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0037 | 0.0037 |
Echinococcus granulosus | alkaline phosphatase | 0.0165 | 0.0989 | 0.0988 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0877 | 0.0877 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0037 | 0.0037 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0015 | 0.0008 | 0.0007 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0037 | 0.0037 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.006 | 0.006 |
Toxoplasma gondii | aldose reductase, putative | 0.1542 | 1 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0047 | 0.0214 | 0.0213 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.1542 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Echinococcus multilocularis | alkaline phosphatase, intestinal, gene 2 | 0.0165 | 0.0989 | 0.0988 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0496 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0037 | 0.0037 |
Onchocerca volvulus | 0.1542 | 1 | 1 | |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0017 | 0.0018 | 0.0017 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0137 | 0.0135 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.1542 | 1 | 1 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0018 | 0.0017 |
Echinococcus granulosus | aldo keto reductase | 0.1542 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1542 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0037 | 0.0037 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0008 | 0.0007 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0214 | 0.0213 |
Trypanosoma brucei | prostaglandin f synthase | 0.1542 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0447 | 0.2831 | 0.283 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0447 | 0.2831 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0037 | 0.0037 |
Trypanosoma brucei | cytochrome P450, putative | 0.0023 | 0.006 | 0.0058 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1542 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0037 | 0.0035 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0037 | 0.0037 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0904 | 0.5828 | 0.5828 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0015 | 0.0008 | 0.0007 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0496 | 0.0495 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0037 | 0.0037 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0047 | 0.0214 | 0.0214 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0037 | 0.0037 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1542 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.006 | 0.006 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.006 | 0.0058 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0037 | 0.0035 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0447 | 0.2831 | 0.283 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0148 | 0.0877 | 0.0877 |
Schistosoma mansoni | potassium channel beta | 0.0447 | 0.2831 | 0.283 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0037 | 0.0037 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.0996 | 0.0994 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0904 | 0.5828 | 0.5828 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0017 | 0.0018 | 0.0017 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0037 | 0.0035 |
Onchocerca volvulus | 0.0447 | 0.2831 | 0.2804 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1542 | 1 | 1 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0017 | 0.0018 | 0.0017 |
Echinococcus multilocularis | alkaline phosphatase | 0.0165 | 0.0989 | 0.0988 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.008 | 0.008 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.1542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1542 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0037 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0037 | 0.0037 |
Onchocerca volvulus | 0.1542 | 1 | 1 | |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0037 | 0.0035 |
Loa Loa (eye worm) | oxidoreductase | 0.1542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1542 | 1 | 1 |
Mycobacterium leprae | Possible oxidoreductase | 0.0447 | 0.2831 | 0.283 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.1542 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0017 | 0.0018 | 0.0017 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0037 | 0.0037 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0037 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0214 | 0.0213 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0053 | 0.0255 | 0.0255 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0447 | 0.2831 | 0.283 |
Echinococcus granulosus | lamin | 0.0026 | 0.008 | 0.0079 |
Echinococcus granulosus | expressed protein | 0.0017 | 0.0018 | 0.0017 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0496 | 0.0495 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0015 | 0.0008 | 0.0007 |
Loa Loa (eye worm) | cytochrome P450 | 0.0014 | 0.0001 | 0.0001 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.008 | 0.0079 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1542 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0037 | 0.0035 |
Brugia malayi | Cytochrome P450 family protein | 0.0014 | 0.0001 | 0.0001 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0037 | 0.0035 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0037 | 0.0035 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0037 | 0.0037 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0018 | 0.0017 |
Brugia malayi | Cytochrome P450 family protein | 0.0053 | 0.0255 | 0.0255 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0148 | 0.0877 | 0.0877 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.006 | 0.006 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Plasmodium vivax | aldehyde reductase, putative | 0.0447 | 0.2831 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0015 | 0.0008 | 0.0007 |
Mycobacterium tuberculosis | Conserved protein | 0.0447 | 0.2831 | 0.283 |
Giardia lamblia | Aldose reductase | 0.1542 | 1 | 0.5 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0008 | 0.0007 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0008 | 0.0007 |
Onchocerca volvulus | 0.1542 | 1 | 1 | |
Echinococcus granulosus | aldo keto reductase | 0.1542 | 1 | 1 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0672 | 0.431 | 0.4309 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0037 | 0.0035 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0037 | 0.0035 |
Onchocerca volvulus | 0.1542 | 1 | 1 | |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.0496 | 0.0496 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0037 | 0.0035 |
Schistosoma mansoni | lamin | 0.0026 | 0.008 | 0.0079 |
Mycobacterium ulcerans | oxidoreductase | 0.1542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.1542 | 1 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0015 | 0.0008 | 0.0007 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0037 | 0.0037 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0023 | 0.006 | 0.0058 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.1542 | 1 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.0008 | 0.0008 |
Echinococcus granulosus | intestinal type alkaline phosphatase 1 | 0.0165 | 0.0989 | 0.0988 |
Schistosoma mansoni | pol-related | 0.1542 | 1 | 1 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.0447 | 0.2831 | 0.283 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0447 | 0.2831 | 0.2818 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0017 | 0.0018 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0037 | 0.0035 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0037 | 0.0037 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0015 | 0.0008 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.057 | 0.057 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0008 | 0.0007 |
Echinococcus granulosus | intestinal type alkaline phosphatase | 0.0165 | 0.0989 | 0.0988 |
Echinococcus multilocularis | lamin | 0.0026 | 0.008 | 0.0079 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0447 | 0.2831 | 0.283 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0037 | 0.0037 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.1542 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0037 | 0.0035 |
Loa Loa (eye worm) | oxidoreductase | 0.1542 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0447 | 0.2831 | 0.2818 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0037 | 0.0037 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.008 | 0.008 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1542 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0037 | 0.0037 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.008 | 0.0079 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0037 | 0.0037 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0037 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0077 | 0.0077 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1542 | 1 | 1 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0447 | 0.2831 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0008 | 0.0007 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0137 | 0.0135 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0037 | 0.0035 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0447 | 0.2831 | 0.2831 |
Loa Loa (eye worm) | oxidoreductase | 0.1542 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.1542 | 1 | 1 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.0008 | 0.0008 |
Echinococcus multilocularis | intestinal type alkaline phosphatase 1 | 0.0165 | 0.0989 | 0.0988 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0017 | 0.0018 | 0.0017 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0037 | 0.0037 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0447 | 0.2831 | 0.283 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0037 | 0.0035 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1542 | 1 | 1 |
Echinococcus multilocularis | intestinal type alkaline phosphatase | 0.0165 | 0.0989 | 0.0988 |
Entamoeba histolytica | aldose reductase, putative | 0.1542 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0166 | 0.0996 | 0.0994 |
Schistosoma mansoni | alkaline phosphatase | 0.0165 | 0.0989 | 0.0988 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0008 | 0.0007 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1542 | 1 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.1095 | 0.7077 | 0.7076 |
Echinococcus multilocularis | aldo keto reductase | 0.1542 | 1 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.1542 | 1 | 1 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0018 | 0.0017 |
Echinococcus granulosus | alkaline phosphatase intestinal gene 2 | 0.0165 | 0.0989 | 0.0988 |
Echinococcus granulosus | ferritin | 0.0017 | 0.0018 | 0.0017 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.008 | 0.008 |
Onchocerca volvulus | 0.0026 | 0.008 | 0.0044 | |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0008 | 0.0007 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0214 | 0.0213 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.008 | 0.008 |
Schistosoma mansoni | alkaline phosphatase | 0.0165 | 0.0989 | 0.0988 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0137 | 0.0135 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0137 | 0.0135 |
Onchocerca volvulus | 0.0026 | 0.008 | 0.0044 | |
Loa Loa (eye worm) | oxidoreductase | 0.1542 | 1 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0447 | 0.2831 | 0.283 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.1542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1542 | 1 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0023 | 0.006 | 0.0058 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0214 | 0.0213 |
Giardia lamblia | Aldose reductase | 0.1542 | 1 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0047 | 0.0214 | 0.0214 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0037 | 0.0035 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0037 | 0.0035 |
Leishmania major | aldo-keto reductase-like protein | 0.1542 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0101 | 0.057 | 0.057 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0023 | 0.006 | 0.006 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0037 | 0.0035 |
Echinococcus multilocularis | aldo keto reductase | 0.1542 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0026 | 0.008 | 0.0079 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.1542 | 1 | 1 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0018 | 0.0017 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0447 | 0.2831 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0672 | 0.431 | 0.4309 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0447 | 0.2831 | 0.2831 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0037 | 0.0037 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0214 | 0.0213 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0496 | 0.0495 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1542 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.0496 | 0.0496 |
Schistosoma mansoni | lamin | 0.0026 | 0.008 | 0.0079 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0137 | 0.0137 |
Echinococcus multilocularis | aldo keto reductase | 0.1542 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0037 | 0.0037 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0214 | 0.0213 |
Echinococcus multilocularis | ferritin | 0.0017 | 0.0018 | 0.0017 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0037 | 0.0035 |
Entamoeba histolytica | aldose reductase, putative | 0.1542 | 1 | 1 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0447 | 0.2831 | 0.2731 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0008 | 0.0007 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0037 | 0.0037 |
Echinococcus granulosus | aldo keto reductase | 0.1542 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.057 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0037 | 0.0037 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.006 | 0.006 |
Toxoplasma gondii | aldo-keto reductase | 0.0447 | 0.2831 | 0.283 |
Echinococcus granulosus | neuropeptide s receptor | 0.0904 | 0.5828 | 0.5828 |
Schistosoma mansoni | hypothetical protein | 0.0086 | 0.047 | 0.0468 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.1542 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.1542 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0037 | 0.0037 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0447 | 0.2831 | 0.2731 |
Echinococcus multilocularis | aldehyde reductase | 0.1095 | 0.7077 | 0.7076 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0037 | 0.0035 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.079 | 0.5081 | 0.508 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0037 | 0.0037 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.1542 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0037 | 0.0035 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1542 | 1 | 1 |
Echinococcus multilocularis | expressed protein | 0.0017 | 0.0018 | 0.0017 |
Schistosoma mansoni | aldo-keto reductase | 0.1542 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.0996 | 0.0994 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0037 | 0.0037 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0018 | 0.0017 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1542 | 1 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0047 | 0.0214 | 0.0214 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0037 | 0.0035 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0447 | 0.2831 | 0.2818 |
Trypanosoma cruzi | aldo-keto reductase | 0.1542 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0037 | 0.0037 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0037 | 0.0035 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1542 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0214 | 0.0214 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0037 | 0.0037 |
Echinococcus granulosus | aldehyde reductase | 0.1095 | 0.7077 | 0.7076 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1542 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.008 | 0.008 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0037 | 0.0037 |
Onchocerca volvulus | 0.1542 | 1 | 1 | |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.1542 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.1542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1542 | 1 | 1 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0018 | 0.0017 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0018 | 0.0017 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0047 | 0.0214 | 0.0213 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0496 | 0.0495 |
Leishmania major | prostaglandin f synthase, putative | 0.1542 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0037 | 0.0035 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0148 | 0.0877 | 0.0877 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.008 | 0.0079 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1542 | 1 | 1 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0447 | 0.2831 | 0.283 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0037 | 0.0037 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0496 | 0.0495 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0017 | 0.0018 | 0.5 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0672 | 0.431 | 0.4309 |
Echinococcus granulosus | GPCR family 2 | 0.0047 | 0.0214 | 0.0213 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0037 | 0.0035 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (ADMET) | = 20 ug | Toxicity in intracerebroventricularly dosed ICR mouse assessed as induction of convulsion after 2 hrs in absence of fenbufen | ChEMBL. | 18457383 |
Activity (ADMET) | = 20 ug | Toxicity in intracerebroventricularly dosed ICR mouse assessed as induction of convulsion after 2 hrs in presence of fenbufen | ChEMBL. | 18457383 |
MIC (functional) | = 0.008 ug ml-1 | Antibacterial activity against Escherichia coli NIHJ JC2 after 18 hrs by agar dilution method | ChEMBL. | 18457383 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.