Detailed information for compound 999945

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1636.2 | Formula: C80H154N20O15
  • H donors: 21 H acceptors: 15 LogP: 2.33 Rotable bonds: 84
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCCCC[C@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)O)CCCCN)C)CCCCCC)CCCCN)C)NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@@H](CCCCN)N)CCCCCC)C)CCCCN)CCCCCC)C)CCCCN)CCCCN
  • InChi: 1S/C80H154N20O15/c1-9-13-17-21-38-58(95-71(105)57(87)37-25-31-47-81)72(106)88-53(5)67(101)92-62(42-26-32-48-82)76(110)96-59(39-22-18-14-10-2)73(107)89-55(7)69(103)94-64(44-28-34-50-84)78(112)99-65(45-29-35-51-85)79(113)98-61(41-24-20-16-12-4)74(108)90-54(6)68(102)93-63(43-27-33-49-83)77(111)97-60(40-23-19-15-11-3)75(109)91-56(8)70(104)100-66(80(114)115)46-30-36-52-86/h53-66H,9-52,81-87H2,1-8H3,(H,88,106)(H,89,107)(H,90,108)(H,91,109)(H,92,101)(H,93,102)(H,94,103)(H,95,105)(H,96,110)(H,97,111)(H,98,113)(H,99,112)(H,100,104)(H,114,115)/t53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-/m1/s1
  • InChiKey: IGZXQXFNIUUKMH-FMXHHOOWSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0007 0.0008
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0007 0.0017
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0006 0.0012
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0162 0.037
Brugia malayi hypothetical protein 0.0317 0.0625 0.1427
Brugia malayi hypothetical protein 0.0317 0.0625 0.1427
Loa Loa (eye worm) hypothetical protein 0.0034 0.0035 0.0082
Schistosoma mansoni neuropeptide F-like receptor 0.0317 0.0625 0.1514
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Echinococcus granulosus dna polymerase kappa 0.002 0.0007 0.0017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0317 0.0625 0.1514
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.0004 0.0008
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0029 0.0025 0.0061
Echinococcus granulosus sterol regulatory element binding protein 0.0219 0.0421 0.1021
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0019 0.0074
Echinococcus multilocularis fmrfamide receptor 0.0317 0.0625 0.0625
Echinococcus granulosus neuropeptide Y receptor 0.0317 0.0625 0.1514
Brugia malayi hypothetical protein 0.0028 0.0023 0.0052
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0553 0.1115 0.6484
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0317 0.0625 0.0625
Brugia malayi Carboxylesterase family protein 0.0034 0.0035 0.008
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0029 0.0025 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0012
Echinococcus multilocularis expressed conserved protein 0.048 0.0964 0.0964
Brugia malayi cytochrome b 0.0261 0.0509 0.1162
Onchocerca volvulus Huntingtin homolog 0.0143 0.0263 0.0825
Loa Loa (eye worm) cytochrome b 0.0261 0.0509 0.1231
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0007 0.0011
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.0065 0.0158
Toxoplasma gondii patched family protein 0.0031 0.003 0.0122
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0025 0.0123
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0094 0.0226
Loa Loa (eye worm) MH2 domain-containing protein 0.0239 0.0463 0.112
Brugia malayi steroid hormone receptor 0.0053 0.0075 0.017
Echinococcus granulosus BC026374 protein S09 family 0.0034 0.0035 0.0085
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0075 0.0181
Brugia malayi RNA binding protein 0.0062 0.0094 0.0213
Brugia malayi Doublecortin family protein 0.0046 0.0061 0.0138
Entamoeba histolytica protein kinase domain containing protein 0.0131 0.0238 0.2289
Echinococcus granulosus tm gpcr rhodopsin 0.0317 0.0625 0.1514
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.0004 0.0002
Brugia malayi G protein-coupled receptor 0.0317 0.0625 0.1427
Echinococcus multilocularis nibrin 0.0019 0.0006 0.0006
Leishmania major carbonic anhydrase-like protein 0.2 0.4129 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.0625 0.1514
Echinococcus granulosus neuropeptide Y receptor 0.0317 0.0625 0.1514
Trichomonas vaginalis glucosylceramidase, putative 0.0842 0.1718 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0569 0.3297
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.2 0.4129 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0055 0.0165
Onchocerca volvulus Protein ultraspiracle homolog 0.0053 0.0075 0.0222
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.022 0.0533
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0006 0.0013
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0006 0.0013
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0054 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0017 0.0041
Brugia malayi Dopamine receptor protein 2 0.0317 0.0625 0.1427
Echinococcus granulosus para nitrobenzyl esterase 0.0034 0.0035 0.0085
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0057
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0094 0.0226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.0625 0.1514
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0007 0.0008
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0053 0.0075 0.0181
Brugia malayi CHE-14 protein 0.0219 0.0421 0.0962
Brugia malayi hypothetical protein 0.0317 0.0625 0.1427
Echinococcus multilocularis casein kinase ii subunit alpha 0.0131 0.0238 0.0238
Brugia malayi Dopamine receptor 0.0317 0.0625 0.1427
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0343 0.0343
Echinococcus granulosus alpha 1A adrenergic receptor 0.0317 0.0625 0.1514
Schistosoma mansoni hypothetical protein 0.002 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0485 0.0975 0.2358
Schistosoma mansoni thyroid hormone receptor 0.0053 0.0075 0.0181
Plasmodium vivax SET domain protein, putative 0.0031 0.0031 0.0317
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0317 0.0625 0.1512
Brugia malayi photoreceptor-specific nuclear receptor 0.0053 0.0075 0.017
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0054 0.0054
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0019 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0006 0.0012
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0007 0.0017
Brugia malayi G-protein coupled receptor 0.0317 0.0625 0.1427
Brugia malayi Carboxylesterase family protein 0.0199 0.038 0.0868
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0055 0.0502
Brugia malayi Patched related family protein 4 0.0031 0.003 0.0067
Schistosoma mansoni transcription factor LCR-F1 0.0106 0.0186 0.045
Brugia malayi AMP-binding enzyme family protein 0.0097 0.0168 0.0383
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Schistosoma mansoni hypothetical protein 0.0095 0.0162 0.0393
Echinococcus granulosus acetylcholinesterase 0.0199 0.038 0.0921
Schistosoma mansoni rab6-interacting 0.0046 0.0061 0.0147
Echinococcus granulosus lipoxygenase domain containing protein 0.0046 0.0061 0.0147
Schistosoma mansoni opsin-like receptor 0.0317 0.0625 0.1514
Echinococcus granulosus cpg binding protein 0.0062 0.0094 0.0227
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Loa Loa (eye worm) patched family protein 0.0031 0.003 0.0069
Echinococcus granulosus Niemann Pick C1 protein 0.0511 0.1028 0.2491
Echinococcus granulosus expressed conserved protein 0.048 0.0964 0.2335
Echinococcus multilocularis protein patched 0.0219 0.0421 0.0421
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0519 0.1045 0.2531
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Entamoeba histolytica acyl-CoA synthetase, putative 0.0097 0.0168 0.1602
Schistosoma mansoni amine GPCR 0.0317 0.0625 0.1514
Echinococcus granulosus acetylcholinesterase 0.0199 0.038 0.0921
Echinococcus granulosus dnaJ subfamily B 0.0807 0.1646 0.3986
Echinococcus multilocularis serotonin receptor 0.1821 0.3756 0.3756
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0053 0.0075 0.0178
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0025 0.0067
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0007 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0108 0.0335
Brugia malayi hypothetical protein 0.0317 0.0625 0.1427
Loa Loa (eye worm) hypothetical protein 0.1045 0.214 0.5182
Brugia malayi Carboxylesterase family protein 0.0199 0.038 0.0868
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0108 0.0335
Brugia malayi hypothetical protein 0.0019 0.0006 0.0012
Mycobacterium ulcerans acetyl-CoA synthetase 0.0029 0.0025 0.0067
Loa Loa (eye worm) carboxylesterase 0.0199 0.038 0.0918
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0097 0.0168 0.0525
Plasmodium falciparum casein kinase 2, alpha subunit 0.0131 0.0238 0.1098
Echinococcus granulosus carbonic anhydrase 0.1045 0.214 0.5184
Brugia malayi Bromodomain containing protein 0.0077 0.0125 0.0285
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0006 0.0006
Toxoplasma gondii hypothetical protein 0.0031 0.003 0.0122
Loa Loa (eye worm) steroid hormone receptor 0.0053 0.0075 0.0178
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0053 0.0075 0.0075
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0035 0.0085
Plasmodium vivax cytochrome b 0.0428 0.0856 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0025 0.0051
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0094 0.0213
Loa Loa (eye worm) hypothetical protein 0.0073 0.0117 0.0279
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0097 0.0168 0.0525
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0007 0.002
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0007 0.0018
Brugia malayi hypothetical protein 0.0046 0.0061 0.0138
Loa Loa (eye worm) hypothetical protein 0.0053 0.0075 0.0178
Loa Loa (eye worm) hypothetical protein 0.0095 0.0162 0.039
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0019 0.0043
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0006 0.0013
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0029 0.0025 0.0067
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0007 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0025 0.0067
Brugia malayi hypothetical protein 0.0019 0.0006 0.0012
Onchocerca volvulus 0.0031 0.003 0.0077
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0317 0.0625 0.0625
Echinococcus granulosus neuropeptides capa receptor 0.0317 0.0625 0.1514
Plasmodium falciparum carbonic anhydrase 0.1045 0.214 1
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0025 0.0067
Echinococcus granulosus neuropeptides capa receptor 0.0317 0.0625 0.1514
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.0004 0.0002
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0007 0.0033
Schistosoma mansoni DNA polymerase eta 0.002 0.0007 0.0017
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0017 0.0041
Echinococcus multilocularis carbonic anhydrase 0.1045 0.214 0.214
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0007 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0842 0.1718 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0299 0.0588 0.1343
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.0168 0.0398
Echinococcus granulosus zinc finger protein 0.0022 0.0012 0.0029
Brugia malayi Carboxylesterase family protein 0.0034 0.0035 0.008
Onchocerca volvulus 0.0112 0.0199 0.0619
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0053 0.0075 0.0181
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.0004 0.0002
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Echinococcus multilocularis sex peptide receptor 0.0317 0.0625 0.0625
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Onchocerca volvulus 0.0053 0.0075 0.0222
Loa Loa (eye worm) melatonin receptor type 1A 0.0317 0.0625 0.1512
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.026 0.082
Echinococcus multilocularis geminin 0.0692 0.1406 0.1406
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0019 0.0185
Onchocerca volvulus 0.0029 0.0025 0.0061
Echinococcus granulosus survival motor neuron protein 1 0.0551 0.1111 0.2691
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0025 0.0067
Brugia malayi Niemann-Pick C1 protein precursor 0.0511 0.1028 0.2347
Trichomonas vaginalis replication factor C large subunit, putative 0.0019 0.0006 0.0012
Echinococcus multilocularis expressed protein 0.0378 0.0751 0.0751
Brugia malayi hypothetical protein 0.0317 0.0625 0.1427
Giardia lamblia Fructose-bisphosphate aldolase 0.029 0.0569 1
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0054 0.0123
Brugia malayi Inositol-1 0.0043 0.0055 0.0125
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Brugia malayi glutaminase DH11.1 0.032 0.0631 0.1439
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0073 0.0117 0.0279
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0007 0.0008
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Loa Loa (eye worm) hypothetical protein 0.0199 0.038 0.0918
Loa Loa (eye worm) hypothetical protein 0.0205 0.0391 0.0945
Brugia malayi hypothetical protein 0.0106 0.0186 0.0424
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0317 0.0625 0.0625
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0094 0.0227
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.0625 0.0625
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0053 0.0075 0.0181
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0029 0.0025 0.0025
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0162 0.0162
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.0569 0.5515
Echinococcus multilocularis g protein coupled receptor 0.0317 0.0625 0.0625
Trichomonas vaginalis glucosylceramidase, putative 0.0553 0.1115 0.6484
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0029 0.0025 0.0098
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.022 0.0692
Schistosoma mansoni neuropeptide receptor 0.0317 0.0625 0.1514
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.0625 0.1514
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0053 0.0075 0.017
Trichomonas vaginalis glutaminase, putative 0.032 0.0631 0.3657
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0029 0.0025 0.0205
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0034 0.0035 0.0035
Brugia malayi nuclear hormone receptor 0.0025 0.0017 0.0038
Schistosoma mansoni hypothetical protein 0.0211 0.0405 0.0981
Brugia malayi GnHR receptor homolog 0.0317 0.0625 0.1427
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0317 0.0625 0.1514
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0043 0.0054 0.0898
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.0053
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0025 0.0067
Onchocerca volvulus 0.0241 0.0467 0.1476
Echinococcus granulosus neuropeptide receptor 0.0317 0.0625 0.1514
Loa Loa (eye worm) G-protein coupled receptor 0.0317 0.0625 0.1512
Brugia malayi hypothetical protein 0.0031 0.003 0.0067
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0025 0.0057
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0034 0.0035 0.0101
Echinococcus granulosus RUN 0.0046 0.0061 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0006 0.0023
Echinococcus multilocularis neuropeptide receptor 0.0317 0.0625 0.0625
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0317 0.0625 0.1427
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0108 0.0335
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0162 0.0393
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Brugia malayi DKFZp564C0469 protein 0.0019 0.0006 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0343 0.0831
Onchocerca volvulus 0.0025 0.0017 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0007 0.0015
Echinococcus multilocularis fmrfamide receptor 0.0317 0.0625 0.0625
Echinococcus granulosus neuroligin 0.0034 0.0035 0.0085
Echinococcus multilocularis FTZ F1 alpha 0.0053 0.0075 0.0075
Echinococcus granulosus expressed protein 0.0378 0.0751 0.1819
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.0004 0.0002
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0006 0.001
Echinococcus multilocularis Niemann Pick C1 protein 0.0511 0.1028 0.1028
Schistosoma mansoni hypothetical protein 0.0211 0.0405 0.0981
Loa Loa (eye worm) oxidoreductase 0.0029 0.0025 0.0057
Schistosoma mansoni loxhd1 0.0046 0.0061 0.0147
Echinococcus granulosus allatostatin A receptor 0.0317 0.0625 0.1514
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0004 0.0004
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0019 0.0046
Echinococcus granulosus biogenic amine 5HT receptor 0.0317 0.0625 0.1514
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0017 0.0017
Schistosoma mansoni carbonic anhydrase-related 0.1045 0.214 0.5184
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0012
Brugia malayi ecdysteroid receptor 0.0053 0.0075 0.017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.0625 0.1514
Loa Loa (eye worm) intermediate filament protein 0.0061 0.0091 0.0219
Schistosoma mansoni opsin-like receptor 0.0317 0.0625 0.1514
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0018 0.0043
Schistosoma mansoni hypothetical protein 0.0205 0.0391 0.0947
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0317 0.0625 0.1983
Echinococcus granulosus somatostatin receptor 0.0317 0.0625 0.1514
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0019 0.0072
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0007 0.0015
Mycobacterium tuberculosis Probable ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit) 0.1521 0.313 1
Onchocerca volvulus 0.0031 0.003 0.0077
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0025 0.0061
Onchocerca volvulus 0.0317 0.0625 0.1983
Loa Loa (eye worm) hypothetical protein 0.0053 0.0075 0.0178
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0317 0.0625 0.1427
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0007 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Onchocerca volvulus Phospholipase A2 homolog 0.0102 0.0178 0.0551
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.2 0.4129 0.9424
Echinococcus granulosus tachykinin peptides receptor 99D 0.0317 0.0625 0.1514
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0569 0.3297
Brugia malayi nuclear receptor RXR 0.0025 0.0017 0.0038
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0053 0.0075 0.0181
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0025 0.0057
Loa Loa (eye worm) hypothetical protein 0.0073 0.0117 0.0279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0053 0.0075 0.0178
Brugia malayi follicle stimulating hormone receptor 0.0317 0.0625 0.1427
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0019 0.009
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Brugia malayi hypothetical protein 0.0026 0.0019 0.0044
Onchocerca volvulus 0.0317 0.0625 0.1983
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0317 0.0625 0.1512
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0006 0.0006
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0097 0.0168 0.0519
Echinococcus granulosus serotonin receptor 0.0317 0.0625 0.1514
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0025 0.0123
Brugia malayi ecdysone receptor 0.0025 0.0017 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0053 0.0075 0.017
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0006 0.0009
Schistosoma mansoni neuropeptide receptor 0.0317 0.0625 0.1514
Trichomonas vaginalis CMGC family protein kinase 0.0131 0.0238 0.1368
Brugia malayi Serotonin receptor 0.2122 0.4382 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0094 0.0094
Echinococcus granulosus G protein coupled receptor 139 0.0317 0.0625 0.1514
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0083 0.0198
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0014
Schistosoma mansoni hypothetical protein 0.0211 0.0405 0.0981
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Echinococcus multilocularis carbonic anhydrase 0.1045 0.214 0.214
Echinococcus granulosus g protein coupled receptor 0.0317 0.0625 0.1514
Brugia malayi latrophilin 2 splice variant baaae 0.0205 0.0391 0.0893
Plasmodium vivax unspecified product 0.0131 0.0238 0.2751
Schistosoma mansoni DNA ligase IV 0.0019 0.0006 0.0013
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0023 0.0056
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0006 0.0006
Onchocerca volvulus 0.0031 0.003 0.0077
Schistosoma mansoni neuropeptide receptor 0.0317 0.0625 0.1514
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0343 0.0831
Schistosoma mansoni carbonic anhydrase-related 0.1045 0.214 0.5184
Schistosoma mansoni neuroligin 3 (S09 family) 0.0034 0.0035 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Echinococcus granulosus peptide allatostatin:somatostatin 0.0317 0.0625 0.1514
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0004 0.0008
Entamoeba histolytica hypothetical protein 0.0106 0.0186 0.1779
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0317 0.0625 0.1514
Onchocerca volvulus 0.0034 0.0035 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0007 0.0008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0317 0.0625 0.0625
Schistosoma mansoni amine GPCR 0.0317 0.0625 0.1514
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0019 0.0019
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0317 0.0625 0.1514
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0006 0.0013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0017 0.0041
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0094 0.0224
Giardia lamblia Kinase, CMGC CK2 0.0131 0.0238 0.415
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0053 0.0075 0.017
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0569 0.3297
Schistosoma mansoni hypothetical protein 0.0095 0.0162 0.0393
Onchocerca volvulus 0.0317 0.0625 0.1983
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Trichomonas vaginalis CMGC family protein kinase 0.0131 0.0238 0.1368
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0006 0.0013
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0025 0.0051
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0017 0.0041
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0053 0.0075 0.0075
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0034 0.0035 0.0185
Onchocerca volvulus 0.0034 0.0035 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0025 0.0051
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0019 0.0038
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0034 0.0035 0.0101
Loa Loa (eye worm) patched family protein 0.0031 0.003 0.0069
Plasmodium falciparum lipid/sterol:H+ symporter 0.0031 0.003 0.0122
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0025 0.0056
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0025 0.0067
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0006 0.0013
Brugia malayi tailless protein 0.0025 0.0017 0.0038
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0317 0.0625 0.1514
Trypanosoma brucei Casein kinase II 0.0131 0.0238 0.0569
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0017 0.0036
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.022 0.0692
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.0625 0.1514
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Plasmodium vivax acetyl-CoA synthetase, putative 0.0029 0.0025 0.0247
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0019 0.0074
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Loa Loa (eye worm) hypothetical protein 0.0199 0.038 0.0918
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.007 0.0111 0.0345
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0054 0.0296
Wolbachia endosymbiont of Brugia malayi cytochrome b subunit of the bc complex 0.0428 0.0856 1
Schistosoma mansoni inositol monophosphatase 0.0043 0.0055 0.0133
Loa Loa (eye worm) hypothetical protein 0.0073 0.0117 0.0279
Trypanosoma brucei C-8 sterol isomerase, putative 0.0819 0.167 0.404
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1045 0.214 0.4885
Loa Loa (eye worm) hypothetical protein 0.0097 0.0168 0.0403
Onchocerca volvulus 0.0317 0.0625 0.1983
Loa Loa (eye worm) neuropeptide F receptor 0.0317 0.0625 0.1512
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Echinococcus multilocularis carbonic anhydrase 0.1045 0.214 0.214
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0055 0.0133
Brugia malayi RE15519p 0.0317 0.0625 0.1427
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Loa Loa (eye worm) hypothetical protein 0.1821 0.3756 0.9096
Brugia malayi hypothetical protein 0.0025 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0034 0.0035 0.0082
Toxoplasma gondii hypothetical protein 0.1045 0.214 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0317 0.0625 0.0625
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0317 0.0625 0.1514
Schistosoma mansoni RAR-like nuclear receptor 0.0053 0.0075 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0075 0.017
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0317 0.0625 0.1512
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.0625 0.0625
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0006 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0343 0.0831
Brugia malayi Tachykinin-like peptides receptor 99D 0.0317 0.0625 0.1427
Echinococcus multilocularis RUN 0.0046 0.0061 0.0061
Echinococcus multilocularis BC026374 protein (S09 family) 0.0034 0.0035 0.0035
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0006 0.0013
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0004 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0569 0.3297
Echinococcus multilocularis sterol regulatory element binding protein 0.0219 0.0421 0.0421
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Brugia malayi putative neuropeptide receptor NPR1 0.0317 0.0625 0.1427
Loa Loa (eye worm) glutaminase 2 0.032 0.0631 0.1525
Onchocerca volvulus 0.0317 0.0625 0.1983
Onchocerca volvulus Neuropeptide F receptor homolog 0.0317 0.0625 0.1983
Brugia malayi ORL1-like opioid receptor 0.0317 0.0625 0.1427
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Mycobacterium ulcerans ubiquinol-cytochrome C reductase QcrB 0.1521 0.313 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0094 0.0225
Brugia malayi Myosin head containing protein 0.0031 0.003 0.0067
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.0004 0.0002
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0097 0.0168 0.0519
Brugia malayi MH2 domain containing protein 0.0239 0.0463 0.1057
Brugia malayi hypothetical protein 0.0317 0.0625 0.1427
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0017 0.0041
Onchocerca volvulus 0.0061 0.0091 0.0275
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0029 0.0025 0.0067
Schistosoma mansoni hypothetical protein 0.0046 0.0061 0.0147
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0007 0.0011
Schistosoma mansoni topbp1 0.0019 0.0006 0.0013
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0299 0.0588 0.1422
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.007 0.0111 0.0345
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0075 0.0075
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0017 0.0038
Giardia lamblia GTOR 0.0019 0.0004 0.0014
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0019 0.0037
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Trichomonas vaginalis glucosylceramidase, putative 0.0582 0.1177 0.6845
Onchocerca volvulus Protein patched homolog 0.0031 0.003 0.0077
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.0055 0.0604
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.0406 0.0981
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0007 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0006 0.0005
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Brugia malayi PHD-finger family protein 0.0028 0.0023 0.0052
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0275 0.0537 0.0537
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.0625 0.0625
Brugia malayi topoisomerase 0.0019 0.0006 0.0012
Mycobacterium ulcerans hypothetical protein 0.0097 0.0168 0.0525
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.0625 0.1514
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0017 0.0038
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0025 0.0051
Onchocerca volvulus 0.0031 0.0031 0.008
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0017 0.0041
Loa Loa (eye worm) hypothetical protein 0.0048 0.0066 0.0157
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0029 0.0025 0.0067
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0029 0.0025 0.006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0299 0.0588 0.1343
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0317 0.0625 0.0625
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0106 0.0186 0.045
Schistosoma mansoni opsin-like receptor 0.0317 0.0625 0.1514
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0006 0.0005
Loa Loa (eye worm) inositol-1 0.0043 0.0055 0.013
Schistosoma mansoni thyroid hormone receptor 0.0053 0.0075 0.0181
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0055 0.03
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0055
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0007 0.0008
Mycobacterium ulcerans carboxylesterase, LipT 0.0034 0.0035 0.0101
Schistosoma mansoni myosin xvIII 0.0317 0.0625 0.1514
Echinococcus multilocularis protein dispatched 1 0.025 0.0486 0.0486
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0053 0.0075 0.0075
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0025 0.0056
Onchocerca volvulus 0.0031 0.003 0.0077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.0625 0.1514
Mycobacterium ulcerans glutaminase 0.032 0.0631 0.2005
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0073 0.0117 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0055 0.03
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Onchocerca volvulus 0.0029 0.0025 0.0061
Brugia malayi protein C24B5.3 0.0031 0.003 0.0067
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0007 0.0008
Brugia malayi CXXC zinc finger family protein 0.0057 0.0083 0.0189
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0006 0.0009
Brugia malayi Putative carbonic anhydrase 5 precursor 0.2 0.4129 0.9424
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0053 0.0075 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0054 0.0296
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0275 0.0537 0.13
Entamoeba histolytica hypothetical protein 0.0026 0.0019 0.0151
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0569 0.3297
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0317 0.0625 0.1512
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.1045 0.214 0.4885
Loa Loa (eye worm) hypothetical protein 0.006 0.0089 0.0213
Loa Loa (eye worm) hypothetical protein 0.0034 0.0035 0.0082
Echinococcus multilocularis Polycystic kidney disease protein 0.0046 0.0061 0.0061
Schistosoma mansoni retinoic acid receptor RXR 0.0053 0.0075 0.0181
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.0168 0.0525
Onchocerca volvulus Bile acid receptor homolog 0.0053 0.0075 0.0222
Onchocerca volvulus 0.0317 0.0625 0.1983
Loa Loa (eye worm) transcription factor SMAD2 0.0239 0.0463 0.112
Loa Loa (eye worm) RNA binding protein 0.0062 0.0094 0.0224
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Loa Loa (eye worm) hypothetical protein 0.0073 0.0117 0.0279
Entamoeba histolytica hypothetical protein 0.0019 0.0006 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0053 0.0075 0.017
Schistosoma mansoni hypothetical protein 0.0317 0.0625 0.1514
Entamoeba histolytica acyl-coA synthetase, putative 0.0097 0.0168 0.1602
Toxoplasma gondii cytochrome b 0.0428 0.0856 0.399
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0317 0.0625 0.1514
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0019 0.0038
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.022 0.0533
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Brugia malayi hypothetical protein 0.0025 0.0017 0.0038
Schistosoma mansoni neuropeptide receptor 0.0317 0.0625 0.1514
Plasmodium falciparum acyl-CoA synthetase 0.0073 0.0117 0.0529
Loa Loa (eye worm) hypothetical protein 0.0299 0.0588 0.1422
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0343 0.0831
Brugia malayi hypothetical protein 0.0317 0.0625 0.1427
Loa Loa (eye worm) hypothetical protein 0.0143 0.0263 0.0635
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0075 0.0181
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0053 0.0075 0.0222
Onchocerca volvulus 0.0317 0.0625 0.1983
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0106 0.0186 0.1779
Trichomonas vaginalis CMGC family protein kinase 0.0131 0.0238 0.1368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0131 0.0238 0.1368
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0006 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.0131 0.0238 0.1368
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0025 0.0051
Schistosoma mansoni hypothetical protein 0.0095 0.0162 0.0393
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0007 0.0008
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1045 0.214 0.4885
Brugia malayi AKH receptor 0.0317 0.0625 0.1427
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.007 0.0111 0.027
Schistosoma mansoni polycystin 1-related 0.0046 0.0061 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0075 0.017
Brugia malayi Patched related family protein 10 0.0031 0.003 0.0067
Schistosoma mansoni acetyl-CoA synthetase 0.0029 0.0025 0.006
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0006 0.0005
Echinococcus multilocularis carbonic anhydrase II 0.2 0.4129 0.4129
Echinococcus granulosus microtubule associated protein 2 0.1607 0.331 0.8016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0025 0.0067
Loa Loa (eye worm) hypothetical protein 0.0269 0.0524 0.1267
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0031 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0075 0.017
Schistosoma mansoni hypothetical protein 0.0317 0.0625 0.1514
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0073 0.0117 0.0361
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0511 0.1028 1
Echinococcus multilocularis lamin dm0 0.0061 0.0091 0.0091
Schistosoma mansoni inositol monophosphatase 0.0043 0.0055 0.0133
Echinococcus granulosus casein kinase ii subunit alpha 0.0131 0.0238 0.0577
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.0162 0.0162
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0006 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0511 0.1028 0.2489
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0097 0.0168 0.0525
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0317 0.0625 0.0625
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0065 0.0158
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Mycobacterium tuberculosis Carboxylesterase LipT 0.0034 0.0035 0.0101
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0007 0.0016
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0004 0.0002
Brugia malayi neuropeptide F receptor 0.0317 0.0625 0.1427
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.0625 0.0625
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0053 0.0075 0.0178
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0017 0.0041
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0017 0.0041
Entamoeba histolytica hypothetical protein 0.0019 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0106 0.0186 0.0186
Echinococcus multilocularis microtubule associated protein 2 0.1607 0.331 0.331
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0035 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0012
Echinococcus multilocularis Niemann Pick C1 protein 0.073 0.1485 0.1485
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0317 0.0625 0.0625
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0025 0.0051
Brugia malayi Patched related family protein 12 0.0031 0.003 0.0067
Entamoeba histolytica hypothetical protein 0.0106 0.0186 0.1779
Entamoeba histolytica hypothetical protein 0.0019 0.0006 0.0019
Echinococcus multilocularis g-protein coupled receptor 0.0317 0.0625 0.0625
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.0625 0.1514
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0317 0.0625 0.1514
Brugia malayi Phospholipase A2 family protein 0.0102 0.0178 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Schistosoma mansoni acetylcholinesterase 0.0034 0.0035 0.0085
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0053 0.0075 0.0178
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Echinococcus granulosus orexin receptor type 2 0.0317 0.0625 0.1514
Loa Loa (eye worm) hypothetical protein 0.0053 0.0075 0.0178
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.0054 0.0124
Trichomonas vaginalis glucosylceramidase, putative 0.0553 0.1115 0.6484
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0026 0.0026
Schistosoma mansoni cytochrome b 0.0261 0.0509 0.1234
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Schistosoma mansoni hypothetical protein 0.0317 0.0625 0.1514
Schistosoma mansoni microtubule-associated protein tau 0.1607 0.331 0.8016
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0053 0.0075 0.0181
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.0004 0.0002
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.0004 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0094 0.0226
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0094 0.0224
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0034 0.0035 0.0085
Brugia malayi hypothetical protein 0.0317 0.0625 0.1427
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0007 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0054 0.0296
Loa Loa (eye worm) hypothetical protein 0.0061 0.0091 0.0219
Schistosoma mansoni zinc finger protein 0.0025 0.0017 0.0041
Entamoeba histolytica hypothetical protein 0.0019 0.0006 0.0019
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0006 0.0013
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0006 0.0006
Onchocerca volvulus 0.0034 0.0035 0.0095
Loa Loa (eye worm) carbonic anhydrase 3 0.2 0.4129 1
Schistosoma mansoni BC026374 protein (S09 family) 0.0034 0.0035 0.0085
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0006 0.0011
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0039 0.0093
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0011 0.0019
Schistosoma mansoni amine GPCR 0.0317 0.0625 0.1514
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0018 0.0018
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0023 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0317 0.0625 0.1427
Schistosoma mansoni zinc finger protein 0.0022 0.0012 0.0029
Echinococcus multilocularis acetylcholinesterase 0.0199 0.038 0.038
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0006 0.0013
Echinococcus multilocularis ecdysone induced protein 78C 0.0053 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.1045 0.214 0.5184
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0053 0.0075 0.0181
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0131 0.0238 0.2751
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0006 0.0012
Echinococcus granulosus Niemann Pick C1 protein 0.073 0.1485 0.3596
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0007 0.0008
Loa Loa (eye worm) doublecortin family protein 0.0046 0.0061 0.0144
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0006 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0025 0.0067
Echinococcus multilocularis GPCR, family 2 0.0095 0.0162 0.0162
Trichomonas vaginalis glucosylceramidase, putative 0.0553 0.1115 0.6484
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Trypanosoma cruzi casein kinase II, putative 0.0131 0.0238 0.0569
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0125 0.0302
Echinococcus multilocularis allatostatin A receptor 0.0317 0.0625 0.0625
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0004 0.0008
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0026 0.0063
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.0168 0.0398
Brugia malayi sulfakinin receptor protein 0.0317 0.0625 0.1427
Loa Loa (eye worm) hypothetical protein 0.1045 0.214 0.5182
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0108 0.0335
Echinococcus multilocularis neuropeptide receptor A26 0.0767 0.1561 0.1561
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0006 0.0005
Onchocerca volvulus 0.0061 0.0091 0.0275
Onchocerca volvulus 0.0317 0.0625 0.1983
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0569 0.3297
Onchocerca volvulus 0.0029 0.0025 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.0053
Brugia malayi Melatonin receptor type 1A 0.0317 0.0625 0.1427
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0007 0.0017
Brugia malayi Pre-SET motif family protein 0.0212 0.0406 0.0926
Brugia malayi hypothetical protein 0.0031 0.003 0.0067
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0017 0.0038
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0004 0.0002
Brugia malayi protein C24B5.3 0.0031 0.003 0.0067
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0029 0.0025 0.0067
Toxoplasma gondii apocytochrome b, putative 0.0428 0.0856 0.399
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0006 0.0013
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0066 0.016
Loa Loa (eye worm) hypothetical protein 0.0045 0.0059 0.014
Plasmodium vivax patched family protein, putative 0.0031 0.003 0.0305
Onchocerca volvulus Huntingtin homolog 0.0143 0.0263 0.0825
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0029 0.0025 0.0067
Loa Loa (eye worm) hypothetical protein 0.0069 0.011 0.0263
Entamoeba histolytica hypothetical protein 0.0106 0.0186 0.1779
Brugia malayi hypothetical protein 0.0031 0.003 0.0067
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0317 0.0625 0.1514
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0017 0.0041
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1045 0.214 0.5182
Schistosoma mansoni cytochrome b 0.0428 0.0856 0.2074
Brugia malayi hypothetical protein 0.0019 0.0006 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Schistosoma mansoni alpha-1 adrenergic receptor 0.0317 0.0625 0.1514
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0007 0.0016
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0317 0.0625 0.0625
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0039 0.0046 0.0128
Echinococcus multilocularis dna polymerase kappa 0.002 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0114
Onchocerca volvulus 0.0034 0.0035 0.0095
Brugia malayi Carboxylesterase family protein 0.0034 0.0035 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.0625 0.0625
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.0625 0.1514
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Loa Loa (eye worm) hypothetical protein 0.0038 0.0044 0.0103
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0057
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.0168 0.0525
Loa Loa (eye worm) hypothetical protein 0.0053 0.0075 0.0178
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0029 0.0025 0.0067
Brugia malayi nuclear receptor NHR-88 0.0025 0.0017 0.0038
Brugia malayi larval opioid receptor 0.0317 0.0625 0.1427
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0007 0.0008
Echinococcus granulosus Polycystic kidney disease protein 0.0046 0.0061 0.0147
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Echinococcus multilocularis g protein coupled receptor 0.0317 0.0625 0.0625
Onchocerca volvulus 0.0057 0.0083 0.0248
Brugia malayi Intermediate filament tail domain containing protein 0.0061 0.0091 0.0209
Echinococcus multilocularis G protein coupled receptor 139 0.0317 0.0625 0.0625
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0029 0.0025 0.0067
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0031 0.0031
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.0625 0.1514
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.0625 0.1514
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0006 0.0013
Trichomonas vaginalis glucosylceramidase, putative 0.0553 0.1115 0.6484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Brugia malayi hypothetical protein 0.0317 0.0625 0.1427
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0054 0.0054
Echinococcus granulosus carboxylesterase 5A 0.0199 0.038 0.0921
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0819 0.167 0.3812
Echinococcus granulosus tm gpcr rhodopsin 0.0317 0.0625 0.1514
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0007 0.0011
Echinococcus granulosus ecdysone induced protein 78C 0.0053 0.0075 0.0181
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0017 0.0041
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0017 0.0017
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0055 0.0125
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0055 0.03
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0004 0.001
Onchocerca volvulus 0.0031 0.003 0.0077
Brugia malayi TAR-binding protein 0.0062 0.0094 0.0213
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0097 0.0168 0.0525
Echinococcus granulosus GPCR family 2 0.0095 0.0162 0.0393
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0006 0.0009
Treponema pallidum fructose-bisphosphate aldolase 0.029 0.0569 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Leishmania major DNA polymerase eta, putative 0.002 0.0007 0.0008
Schistosoma mansoni ap endonuclease 0.0018 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0025 0.0067
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0025 0.0051
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Giardia lamblia Replication factor C, subunit 1 0.0019 0.0006 0.0035
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Schistosoma mansoni survival motor neuron protein 0.0112 0.0199 0.0482
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Brugia malayi Serotonin receptor 0.0317 0.0625 0.1427
Schistosoma mansoni gliotactin 0.0034 0.0035 0.0085
Loa Loa (eye worm) G-protein coupled receptor 0.0317 0.0625 0.1512
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0053 0.0075 0.0181
Brugia malayi G protein-coupled receptor F59B2.13 0.0317 0.0625 0.1427
Loa Loa (eye worm) hypothetical protein 0.0053 0.0075 0.0178
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0025 0.0056
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0025 0.0067
Brugia malayi Patched protein homolog 1 0.0031 0.003 0.0067
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0004 0.0002
Toxoplasma gondii CMGC kinase, CK2 family 0.0131 0.0238 0.1098
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0023 0.0052
Leishmania major hypothetical protein, conserved 0.0026 0.0019 0.0038
Echinococcus granulosus Protein patched homolog 1 0.0219 0.0421 0.1021
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0006 0.0012
Onchocerca volvulus Phospholipase A2 homolog 0.0485 0.0975 0.3101
Trypanosoma brucei unspecified product 0.002 0.0007 0.0008
Brugia malayi PXA domain containing protein 0.0019 0.0006 0.0012
Echinococcus granulosus dro:myosuppressin receptor 0.0317 0.0625 0.1514
Schistosoma mansoni biogenic amine receptor 0.0317 0.0625 0.1514
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Onchocerca volvulus 0.0048 0.0066 0.0193
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0035 0.0082
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0025 0.0067
Schistosoma mansoni protein kinase 0.0131 0.0238 0.0577
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.026 0.082
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0006 0.0012
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0039 0.0039
Echinococcus multilocularis lipoxygenase domain containing protein 0.0046 0.0061 0.0061
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0006 0.0013
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0017 0.0038
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0017 0.0036
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0029 0.0025 0.0067
Loa Loa (eye worm) hypothetical protein 0.0819 0.167 0.4044
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.0625 0.0625
Schistosoma mansoni hypothetical protein 0.0692 0.1406 0.3406
Echinococcus granulosus neuropeptide FF receptor 2 0.0317 0.0625 0.1514
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0317 0.0625 0.1427
Echinococcus granulosus nibrin 0.0019 0.0006 0.0013
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0006 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0007 0.0008
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0019 0.0037
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0317 0.0625 0.1514
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0162 0.037
Schistosoma mansoni lipoxygenase 0.0192 0.0365 0.0883
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.022 0.0692
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0034 0.0035 0.0082
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.0004 0.0002
Loa Loa (eye worm) glutaminase 0.032 0.0631 0.1525
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0065 0.0158
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Onchocerca volvulus 0.1521 0.313 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0343 0.0831
Trypanosoma brucei carbonic anhydrase-like protein 0.2 0.4129 1
Echinococcus granulosus intermediate filament protein 0.0061 0.0091 0.0222
Echinococcus multilocularis para nitrobenzyl esterase 0.0034 0.0035 0.0035
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0017 0.0038
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.007 0.0111 0.0111
Echinococcus multilocularis survival motor neuron protein 1 0.0551 0.1111 0.1111
Echinococcus multilocularis g protein coupled receptor 0.0317 0.0625 0.0625
Brugia malayi PXA domain containing protein 0.0019 0.0006 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Echinococcus multilocularis dnaJ subfamily B 0.0807 0.1646 0.1646
Onchocerca volvulus 0.0317 0.0625 0.1983
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.0162 0.0393
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0004 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.0625 0.1514
Brugia malayi hypothetical protein 0.0028 0.0023 0.0052
Loa Loa (eye worm) hypothetical protein 0.0143 0.0263 0.0635
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.0004 0.0002
Echinococcus granulosus sex peptide receptor 0.0317 0.0625 0.1514
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0317 0.0625 0.1512
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0317 0.0625 0.1514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0019 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0842 0.1718 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1045 0.214 0.4885
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0006 0.0013
Echinococcus granulosus tm gpcr rhodopsin 0.0317 0.0625 0.1514
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0012
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0343 0.0343
Toxoplasma gondii propionate-CoA ligase 0.0029 0.0025 0.0098
Schistosoma mansoni neuropeptide f receptor 76f 0.0317 0.0625 0.1514
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0031 0.0126
Entamoeba histolytica acyl-CoA synthetase, putative 0.0097 0.0168 0.1602
Brugia malayi nuclear hormone receptor 0.0053 0.0075 0.017
Schistosoma mansoni patched 1 0.0219 0.0421 0.1021
Brugia malayi G-protein coupled receptor 0.0317 0.0625 0.1427
Treponema pallidum DNA ligase (lig) 0.0019 0.0006 0.0035
Echinococcus granulosus tumor protein p63 0.0331 0.0654 0.1584
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0419 0.0837 0.2024
Brugia malayi Casein kinase II, alpha chain 0.0131 0.0238 0.0543
Echinococcus granulosus lamin 0.0061 0.0091 0.0222
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0053 0.0075 0.0178
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0017 0.0038
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0317 0.0625 0.1514
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Echinococcus multilocularis serotonin receptor 0.1821 0.3756 0.3756
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0007 0.0018
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0029 0.0025 0.0067
Onchocerca volvulus 0.0031 0.003 0.0077
Schistosoma mansoni steroid hormone receptor ad4bp 0.0053 0.0075 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.0625 0.1514
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.0569 0.5515
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0025 0.0067
Giardia lamblia DINP protein human, muc B family 0.002 0.0007 0.0059
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0343 0.0828
Trichomonas vaginalis set domain proteins, putative 0.0241 0.0467 0.27
Loa Loa (eye worm) carboxylesterase 0.0034 0.0035 0.0082
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0007 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0053 0.0075 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0317 0.0625 0.0625
Loa Loa (eye worm) hypothetical protein 0.0219 0.0421 0.1018
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0023 0.0056
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0026 0.0062
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0033 0.0075
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0317 0.0625 0.1514
Echinococcus multilocularis zinc finger protein 0.0022 0.0012 0.0012
Onchocerca volvulus 0.0317 0.0625 0.1983
Echinococcus granulosus neuropeptide receptor A26 0.0767 0.1561 0.3781
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0044
Schistosoma mansoni biogenic amine receptor 0.0317 0.0625 0.1514
Onchocerca volvulus 0.0317 0.0625 0.1983
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0043 0.0054 0.0123
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0007 0.0015
Echinococcus granulosus ubiquitin specific protease 41 0.0043 0.0054 0.0132
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0125 0.0125
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0421 0.2437
Echinococcus multilocularis orexin receptor type 2 0.0317 0.0625 0.0625
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0023 0.0052
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0317 0.0625 0.1427
Onchocerca volvulus 0.0037 0.0042 0.0116
Echinococcus granulosus biogenic amine 5HT receptor 0.1821 0.3756 0.9096
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Schistosoma mansoni hypothetical protein 0.0106 0.0186 0.045
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0029 0.0025 0.0051
Loa Loa (eye worm) neuropeptide F receptor 0.0317 0.0625 0.1512
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0094 0.0226
Echinococcus granulosus rhodopsin orphan GPCR 0.0317 0.0625 0.1514
Plasmodium vivax acyl-CoA synthetase, putative 0.0073 0.0117 0.1325
Loa Loa (eye worm) hypothetical protein 0.0551 0.1111 0.2689
Brugia malayi hypothetical protein 0.0317 0.0625 0.1427
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0012
Echinococcus multilocularis lipoxygenase domain containing protein 0.0046 0.0061 0.0061
Echinococcus multilocularis cpg binding protein 0.0062 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Schistosoma mansoni glutaminase 0.032 0.0631 0.1527
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0007 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0097 0.0168 0.0403
Brugia malayi Steroid receptor seven-up type 2 0.0053 0.0075 0.017
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0317 0.0625 0.0625
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0018 0.0043
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Brugia malayi Pre-SET motif family protein 0.0031 0.0031 0.007
Schistosoma mansoni nuclear receptor 0.0025 0.0017 0.0041
Toxoplasma gondii histone lysine methyltransferase SET1 0.0111 0.0196 0.09
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0054 0.0123
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0029 0.0025 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0053 0.0075 0.017
Schistosoma mansoni intermediate filament proteins 0.0061 0.0091 0.0222
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0031 0.0074
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0019 0.0006 0.0023
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0343 0.0783
Leishmania major casein kinase II, putative 0.0131 0.0238 0.0569
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0004 0.001
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0199 0.038 0.0921
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Trichomonas vaginalis spcc417.12 protein, putative 0.0034 0.0035 0.0185
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.007 0.0111 0.027
Schistosoma mansoni amine GPCR 0.0317 0.0625 0.1514
Echinococcus multilocularis neuropeptides capa receptor 0.0317 0.0625 0.0625
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Schistosoma mansoni topbp1 0.0019 0.0006 0.0013
Onchocerca volvulus 0.0025 0.0017 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0007 0.0008
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0162 0.039
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.006
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0004 0.0006
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0043 0.0054 0.0132
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.007 0.0111 0.0254
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0025
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0038
Echinococcus multilocularis neuroligin 0.0034 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0053 0.0075 0.0181
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0053 0.0075 0.0178
Plasmodium falciparum cytochrome b 0.0428 0.0856 0.399
Brugia malayi nuclear receptor NHR-88 0.0053 0.0075 0.017
Echinococcus multilocularis neuropeptide s receptor 0.0767 0.1561 0.1561
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0117 0.0361
Loa Loa (eye worm) acetylcholinesterase 1 0.0199 0.038 0.0918
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0006 0.0012
Onchocerca volvulus 0.0317 0.0625 0.1983
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.0625 0.0625
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0033 0.0076
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0006 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0097 0.0168 0.0383
Schistosoma mansoni carbonic anhydrase-related 0.1045 0.214 0.5184
Loa Loa (eye worm) hypothetical protein 0.0043 0.0054 0.0129
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0097 0.0168 0.0525
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0006 0.0013
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0055 0.0125
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.007 0.0111 0.0261
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0017 0.0038
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0029 0.0025 0.0061
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Entamoeba histolytica casein kinase, putative 0.0131 0.0238 0.2289
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0054 0.0132
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0007 0.0014
Onchocerca volvulus 0.0317 0.0625 0.1983
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.0004 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0053 0.0075 0.0178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0053 0.0075 0.017
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0006 0.0013
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0006 0.0006
Schistosoma mansoni nuclear receptor 0.0025 0.0017 0.0041
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.0004 0.0002
Toxoplasma gondii apocytochrome b, putative 0.0167 0.0312 0.1443
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0017 0.0017
Onchocerca volvulus 0.0031 0.003 0.0077
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0317 0.0625 0.1514
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.026 0.0814
Schistosoma mansoni hypothetical protein 0.0317 0.0625 0.1514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0842 0.1718 0.3921
Onchocerca volvulus 0.0046 0.0061 0.0176
Echinococcus granulosus neuropeptide receptor 0.0317 0.0625 0.1514
Trichomonas vaginalis glucosylceramidase, putative 0.0553 0.1115 0.6484
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.0625 0.1514
Trichomonas vaginalis glucosylceramidase, putative 0.0842 0.1718 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0219 0.0421 0.1018
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0006 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0097 0.0168 0.0383
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0097 0.0168 0.0525
Echinococcus multilocularis ubiquitin specific protease 41 0.0043 0.0054 0.0054
Echinococcus multilocularis neuropeptides capa receptor 0.0317 0.0625 0.0625
Schistosoma mansoni rab6-interacting 0.0046 0.0061 0.0147
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Toxoplasma gondii patched family protein 0.0031 0.003 0.0122
Brugia malayi hypothetical protein 0.0034 0.0035 0.008
Echinococcus granulosus carbonic anhydrase 0.1045 0.214 0.5184
Trichomonas vaginalis glucosylceramidase, putative 0.0582 0.1177 0.6845
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0004 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0007 0.0008
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0007 0.0018
Schistosoma mansoni ap endonuclease 0.0018 0.0004 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Brugia malayi conserved hypotetical protein 0.0025 0.0017 0.0038
Echinococcus granulosus FTZ F1 alpha 0.0053 0.0075 0.0181
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0075 0.0181
Loa Loa (eye worm) patched family protein 0.0031 0.003 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0569 0.3297
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0842 0.1718 0.4159
Toxoplasma gondii patched family protein 0.0031 0.003 0.0122
Echinococcus granulosus lamin dm0 0.0061 0.0091 0.0222
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0007 0.0008
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0006 0.0012
Brugia malayi putative neuropeptide receptor 0.0317 0.0625 0.1427
Loa Loa (eye worm) TYRA-2 protein 0.0317 0.0625 0.1512
Brugia malayi Carboxylesterase family protein 0.0034 0.0035 0.008
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.0004 0.0002
Brugia malayi hypothetical protein 0.0019 0.0006 0.0012
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0006 0.0013
Echinococcus multilocularis neuropeptide receptor 0.0317 0.0625 0.0625
Echinococcus multilocularis neuropeptide Y receptor 0.0317 0.0625 0.0625
Schistosoma mansoni growth hormone secretagogue receptor 0.0317 0.0625 0.1514
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Onchocerca volvulus 0.0034 0.0035 0.0095
Echinococcus granulosus lipoxygenase domain containing protein 0.0046 0.0061 0.0147
Loa Loa (eye worm) DR-78 0.0025 0.0017 0.0038
Schistosoma mansoni biogenic amine receptor 0.0317 0.0625 0.1514
Echinococcus granulosus g protein coupled receptor 0.0317 0.0625 0.1514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0053 0.0075 0.0178
Echinococcus granulosus hypothetical protein 0.0317 0.0625 0.1514
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0094 0.0226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0317 0.0625 0.1514
Toxoplasma gondii patched family protein 0.0031 0.003 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.0004 0.0011
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0029 0.0025 0.0098
Schistosoma mansoni neuropeptide F-like receptor 0.0317 0.0625 0.1514
Brugia malayi Dopamine receptor protein 1 0.0317 0.0625 0.1427
Loa Loa (eye worm) hypothetical protein 0.0034 0.0035 0.0082
Plasmodium vivax multidomain scavenger receptor, putative 0.0046 0.0061 0.067
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0075 0.017
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.0053
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0569 0.3297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Schistosoma mansoni cpg binding protein 0.0057 0.0083 0.0201
Echinococcus granulosus fmrfamide receptor 0.0317 0.0625 0.1514
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0317 0.0625 0.1514
Schistosoma mansoni coup transcription factor 0.0053 0.0075 0.0181
Onchocerca volvulus 0.0317 0.0625 0.1983
Loa Loa (eye worm) carboxylesterase 0.0034 0.0035 0.0082
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0819 0.167 0.404
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0842 0.1718 1
Mycobacterium leprae Probable Ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit) 0.1521 0.313 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0061 0.0144
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.0168 0.0398
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0054 0.0123
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Trichomonas vaginalis glucosylceramidase, putative 0.0553 0.1115 0.6484
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Echinococcus granulosus tar DNA binding protein 0.0062 0.0094 0.0226
Onchocerca volvulus 0.0097 0.0168 0.0519
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.2 0.4129 1
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0029 0.0025 0.0067
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.0218 0.0527
Schistosoma mansoni hypothetical protein 0.0112 0.0199 0.0482
Echinococcus granulosus cytochrome B 0.0428 0.0856 0.2074
Plasmodium falciparum LCCL domain-containing protein 0.0046 0.0061 0.0267
Echinococcus multilocularis dna polymerase eta 0.002 0.0007 0.0007
Schistosoma mansoni amine GPCR 0.1668 0.3437 0.8324
Schistosoma mansoni lamin 0.0061 0.0091 0.0222
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0061 0.0091 0.0219
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0017 0.0041
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0029 0.0025 0.0056
Echinococcus granulosus g-protein coupled receptor 0.0317 0.0625 0.1514
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.0004 0.0002
Schistosoma mansoni adenoreceptor 0.0317 0.0625 0.1514
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0029 0.0025 0.0067
Brugia malayi nuclear receptor RXR 0.0028 0.0023 0.0052
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Schistosoma mansoni histamine h1 receptor 0.0317 0.0625 0.1514
Schistosoma mansoni biogenic amine (5HT) receptor 0.0317 0.0625 0.1514
Brugia malayi intermediate filament protein 0.0061 0.0091 0.0209
Brugia malayi hypothetical protein 0.0143 0.0263 0.0601
Loa Loa (eye worm) hypothetical protein 0.0102 0.0178 0.0427
Brugia malayi hypothetical protein 0.0551 0.1111 0.2536
Loa Loa (eye worm) hypothetical protein 0.1045 0.214 0.5182
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.001
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0006 0.001
Echinococcus multilocularis neuropeptide Y receptor 0.0317 0.0625 0.0625
Loa Loa (eye worm) patched family protein 0.0031 0.003 0.0069
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0006 0.0013
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0055 0.0125
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.022 0.0533
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0094 0.0094
Schistosoma mansoni hypothetical protein 0.0692 0.1406 0.3406
Schistosoma mansoni cpg binding protein 0.0062 0.0094 0.0227
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.0168 0.0525
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Onchocerca volvulus 0.0317 0.0625 0.1983
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.0004 0.0004
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0048 0.0065 0.0156
Echinococcus multilocularis dro:myosuppressin receptor 0.0317 0.0625 0.0625
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0039 0.0046 0.0134
Brugia malayi neuropeptide F receptor 0.0317 0.0625 0.1427
Schistosoma mansoni lamin 0.0061 0.0091 0.0222
Schistosoma mansoni biogenic amine (5HT) receptor 0.1821 0.3756 0.9096
Schistosoma mansoni hypothetical protein 0.0211 0.0405 0.0981
Schistosoma mansoni hypothetical protein 0.0095 0.0162 0.0393
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0055 0.0125
Onchocerca volvulus Protein patched homolog 0.0031 0.003 0.0077
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0317 0.0625 0.0625
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0069
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.022 0.1013
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.2 0.4129 1
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Brugia malayi hypothetical protein 0.0046 0.0061 0.0138
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0029 0.0025 0.0067
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0019 0.0006 0.0019
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0025 0.0051
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0317 0.0625 0.0625
Schistosoma mansoni carbonic anhydrase 0.1045 0.214 0.5184
Brugia malayi Bromodomain containing protein 0.0038 0.0043 0.0099
Loa Loa (eye worm) hypothetical protein 0.0046 0.0061 0.0144
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0029 0.0025 0.0098
Loa Loa (eye worm) hypothetical protein 0.0097 0.0168 0.0403
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0317 0.0625 0.0625
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0131 0.0238 0.0574
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0006 0.0013
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.2 0.4129 1
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0025 0.0056
Echinococcus multilocularis neuropeptide FF receptor 2 0.0317 0.0625 0.0625
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Schistosoma mansoni bromodomain containing protein 0.0065 0.0101 0.0245
Brugia malayi Patched family protein 0.0031 0.003 0.0067
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0006 0.0013
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.0004 0.0011
Onchocerca volvulus Glucosylceramidase homolog 0.0553 0.1115 0.3551
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0017 0.0038
Onchocerca volvulus 0.0317 0.0625 0.1983
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0025 0.0056
Loa Loa (eye worm) hypothetical protein 0.0034 0.0035 0.0082
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0317 0.0625 0.1514
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.2 0.4129 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.0054 0.0495
Echinococcus granulosus dna polymerase eta 0.002 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.0053
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Brugia malayi nuclear receptor NHR-67 0.0025 0.0017 0.0038
Leishmania major DNA polymerase kappa, putative 0.002 0.0007 0.0008
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.022 0.0525
Echinococcus multilocularis tumor protein p63 0.0331 0.0654 0.0654
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0016 0.0041
Schistosoma mansoni cpg binding protein 0.0062 0.0094 0.0227
Echinococcus multilocularis somatostatin receptor 0.0317 0.0625 0.0625
Onchocerca volvulus 0.0317 0.0625 0.1983
Echinococcus multilocularis acetylcholinesterase 0.0199 0.038 0.038
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0017 0.0017
Echinococcus multilocularis lamin 0.0061 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0317 0.0625 0.1512
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0035 0.0085
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0317 0.0625 0.1514
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0023 0.0053
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0053 0.0075 0.0181
Schistosoma mansoni hypothetical protein 0.0807 0.1646 0.3986
Echinococcus granulosus 7TM GPCR rhodopsin 0.0317 0.0625 0.1514
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.022 0.0692
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0317 0.0625 0.1514
Echinococcus multilocularis carboxylesterase 5A 0.0199 0.038 0.038
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.0004 0.0002
Loa Loa (eye worm) patched family protein 0.0031 0.003 0.0069
Echinococcus multilocularis thyroid hormone receptor alpha 0.0053 0.0075 0.0075
Echinococcus granulosus 7tm_1 domain containing protein 0.0317 0.0625 0.1514
Loa Loa (eye worm) hypothetical protein 0.1821 0.3756 0.9096
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0055 0.0241
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Brugia malayi hypothetical protein 0.0031 0.003 0.0067
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0043 0.0054 0.0132
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.022 0.022
Trichomonas vaginalis CMGC family protein kinase 0.0131 0.0238 0.1368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0053 0.0075 0.0178
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.1045 0.214 0.4885
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0075 0.017
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0317 0.0625 0.0625
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0023 0.0023
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0007 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0131 0.0238 0.1368
Leishmania major C-8 sterol isomerase-like protein 0.0819 0.167 0.404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0317 0.0625 0.0625
Echinococcus granulosus g protein coupled receptor 0.0317 0.0625 0.1514
Schistosoma mansoni lipoxygenase 0.0275 0.0537 0.13
Loa Loa (eye worm) hypothetical protein 0.0053 0.0075 0.0178
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0019 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0025 0.0067
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0112 0.0199 0.0454
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0019 0.0006 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0317 0.0625 0.1514
Echinococcus multilocularis musashi 0.0061 0.0091 0.0091
Echinococcus granulosus carbonic anhydrase 0.1045 0.214 0.5184
Echinococcus granulosus neuropeptide s receptor 0.0767 0.1561 0.3781
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0075 0.017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0053 0.0075 0.017
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0006 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0075 0.017
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0017 0.0017
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.0004 0.0004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.007 0.0111 0.0345
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.0053
Onchocerca volvulus 0.0046 0.0061 0.0176
Trichomonas vaginalis glucosylceramidase, putative 0.0842 0.1718 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.0065 0.0065
Echinococcus granulosus carbonic anhydrase II 0.2 0.4129 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0053 0.0075 0.0075
Echinococcus granulosus geminin 0.0692 0.1406 0.3406

Activities

Activity type Activity value Assay description Source Reference
LC50 (functional) = 2 uM Cytotoxicity against human DU145 cells assessed as dehydrogenase activity after 24 hrs by flow cytometry-based CCK-8 assay ChEMBL. 19397319
LC50 (functional) = 2.2 uM Cytotoxicity against human MCF7 cells assessed as dehydrogenase activity after 24 hrs by flow cytometry-based CCK-8 assay ChEMBL. 19397319
LC50 (functional) = 2.5 uM Cytotoxicity against human HeLa cells assessed as dehydrogenase activity after 24 hrs by flow cytometry-based CCK-8 assay ChEMBL. 19397319
LC50 (functional) = 2.8 uM Cytotoxicity against human FADU cells assessed as dehydrogenase activity after 24 hrs by flow cytometry-based CCK-8 assay ChEMBL. 19397319
LC50 (ADMET) = 2.8 uM Cytotoxicity against human MRC5 cells assessed as dehydrogenase activity after 24 hrs by flow cytometry-based CCK-8 assay ChEMBL. 19397319

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.