Detailed information for compound 999962

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1057.2 | Formula: C48H76N14O13
  • H donors: 17 H acceptors: 13 LogP: -5.56 Rotable bonds: 44
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)Cc1ccccc1)CCCCN)CO)Cc1ccc(cc1)O)NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](N)C)CCCNC(=N)N
  • InChi: 1S/C48H76N14O13/c1-27(51)40(67)62-39(28(2)64)46(73)59-34(15-10-22-54-48(52)53)42(69)57-32(13-6-8-20-49)41(68)55-25-38(66)56-35(23-30-16-18-31(65)19-17-30)44(71)61-37(26-63)45(72)58-33(14-7-9-21-50)43(70)60-36(47(74)75)24-29-11-4-3-5-12-29/h3-5,11-12,16-19,27-28,32-37,39,63-65H,6-10,13-15,20-26,49-51H2,1-2H3,(H,55,68)(H,56,66)(H,57,69)(H,58,72)(H,59,73)(H,60,70)(H,61,71)(H,62,67)(H,74,75)(H4,52,53,54)/t27-,28+,32-,33-,34-,35-,36-,37-,39-/m0/s1
  • InChiKey: YGGKSEQILOAUIQ-MWUHOBBQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi SET domain containing protein 0.0025 0.0135 0.0272
Echinococcus multilocularis polycomb protein SCMH1 0.0055 0.0449 0.0432
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Schistosoma mansoni ferritin light chain 0.0019 0.0075 0.0098
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.01 0.037
Trypanosoma brucei hypothetical protein, conserved 0.0081 0.0719 0.3653
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0379 0.0498
Onchocerca volvulus 0.0024 0.0132 0.1386
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0128 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0075 0.0397
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0086 0.077 0.1011
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0058 0.0606
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0019 0.0075 0.0099
Brugia malayi Cathepsin L-like precursor 0.0017 0.0058 0.0116
Loa Loa (eye worm) hypothetical protein 0.0063 0.0527 0.1062
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.01 0.0135
Loa Loa (eye worm) MBCTL1 0.0063 0.0527 0.1062
Loa Loa (eye worm) hypothetical protein 0.0196 0.1902 0.3831
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0038 0.0077
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0866 0.1137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0252 0.1325
Loa Loa (eye worm) hypothetical protein 0.0044 0.0338 0.0681
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0058 0.0105
Brugia malayi Latrophilin receptor protein 2 0.0051 0.0412 0.083
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0019 0.0075 0.0111
Mycobacterium ulcerans hypothetical protein 0.0051 0.0412 0.2005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Schistosoma mansoni myelin transcription factor 1 myt1 0.0063 0.0527 0.0692
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0058 0.0304
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0911 0.0895
Echinococcus granulosus pyruvate kinase 0.002 0.0086 0.0113
Schistosoma mansoni netrin receptor unc5 0.0032 0.0213 0.028
Loa Loa (eye worm) hypothetical protein 0.0082 0.0722 0.1454
Brugia malayi beta-lactamase 0.0081 0.0719 0.1448
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0019 0.0001
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0039 0.0279 0.0503
Echinococcus multilocularis histone acetyltransferase MYST2 0.0063 0.0527 0.051
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0279 0.0561
Echinococcus multilocularis protein dispatched 1 0.0049 0.0387 0.037
Brugia malayi hypothetical protein 0.0025 0.0136 0.0275
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0058 0.0304
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0049 0.0099
Leishmania major cAMP-specific phosphodiesterase, putative 0.0019 0.0075 0.02
Brugia malayi hypothetical protein 0.0019 0.0077 0.0155
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0049 0.006
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0449 0.0589
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0196 0.1902 0.362
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0058 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0746 0.3925
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0049 0.006
Schistosoma mansoni intermediate filament proteins 0.0027 0.0165 0.0216
Schistosoma mansoni zinc finger protein 0.0023 0.0115 0.0151
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0135 0.052
Echinococcus granulosus histone lysine methyltransferase setb 0.002 0.0085 0.0112
Trypanosoma brucei phosphoglycerate kinase, putative 0.0072 0.0624 0.3143
Mycobacterium tuberculosis Conserved protein 0.0081 0.0719 0.1349
Mycobacterium ulcerans phosphoglycerate kinase 0.0196 0.1902 1
Echinococcus granulosus tumor protein p63 0.0712 0.7199 0.9453
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0549 0.2743
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0058 0.0304
Plasmodium falciparum pyruvate kinase 0.0039 0.0279 0.129
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0135 0.0499
Loa Loa (eye worm) hypothetical protein 0.0051 0.0412 0.083
Brugia malayi Pyruvate kinase, muscle isozyme 0.0039 0.0279 0.0561
Echinococcus multilocularis phosphoglycerate kinase 1 0.0196 0.1902 0.1887
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Schistosoma mansoni ferritin 0.0019 0.0075 0.0098
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0019 0.0075 0.02
Entamoeba histolytica acyl-coA synthetase, putative 0.0051 0.0412 0.1521
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Trichomonas vaginalis hypothetical protein 0.0025 0.0135 0.071
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.01 0.0202
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0051 0.0412 0.0541
Brugia malayi M-phase phosphoprotein, mpp8 0.0025 0.0135 0.0272
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0135 0.052
Onchocerca volvulus 0.0051 0.0412 0.4318
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0135 0.071
Mycobacterium ulcerans bacterioferritin BfrB 0.0019 0.0075 0.0195
Brugia malayi beta-lactamase family protein 0.0081 0.0719 0.1448
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0196 0.1902 1
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0019 0.0075 0.0058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0135 0.071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0549 0.2743
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0038 0.0041
Entamoeba histolytica hypothetical protein 0.0025 0.0135 0.0499
Trypanosoma cruzi pyruvate kinase 2, putative 0.0039 0.0279 0.129
Echinococcus multilocularis netrin receptor unc 5 0.0032 0.0213 0.0196
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0072 0.0624 0.3143
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0221 0.2156 0.2831
Entamoeba histolytica cysteine protease, putative 0.0017 0.0058 0.0214
Brugia malayi Associated with TFs and helicases family protein 0.0025 0.0135 0.0272
Schistosoma mansoni hypothetical protein 0.0041 0.0308 0.0405
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0866 0.1744
Toxoplasma gondii aldehyde dehydrogenase 0.0074 0.064 0.3232
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0038
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0058 0.0105
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0019 0.0075 0.0099
Schistosoma mansoni aldehyde dehydrogenase 0.0074 0.064 0.0841
Echinococcus multilocularis pyruvate kinase 0.002 0.0086 0.0068
Loa Loa (eye worm) RNA binding protein 0.0205 0.1986 0.4001
Onchocerca volvulus 0.0017 0.0058 0.0606
Leishmania major cathepsin L-like protease 0.0017 0.0058 0.0105
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.01 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0324 0.1705
Echinococcus multilocularis SAM and MBT domain containing protein 0.0055 0.0449 0.0432
Loa Loa (eye worm) hypothetical protein 0.0081 0.0719 0.1448
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0183 0.0779
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0241 0.109
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0519 0.2578
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.01 0.0332
Echinococcus granulosus pyruvate kinase 0.0039 0.0279 0.0366
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0049 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.02
Trypanosoma brucei pyruvate kinase 1, putative 0.0039 0.0279 0.129
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0135 0.071
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0911 0.1836
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0379 0.1829
Onchocerca volvulus 0.0017 0.0058 0.0606
Trichomonas vaginalis D-aminoacylase, putative 0.0081 0.0719 0.378
Echinococcus granulosus pyruvate kinase 0.002 0.0086 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0135 0.071
Brugia malayi intermediate filament protein 0.0027 0.0165 0.0332
Onchocerca volvulus 0.0017 0.0058 0.0606
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0135 0.071
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0035 0.0241 0.0224
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0038 0.0077
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0196 0.1902 1
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0241 0.109
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0075 0.02
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0049 0.006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0038 0.0077
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0058 0.0116
Echinococcus granulosus SAM and MBT domain containing protein 0.0055 0.0449 0.0589
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0055 0.0449 0.4704
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0058 0.0304
Schistosoma mansoni phosphoglycerate kinase 0.0196 0.1902 0.2497
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0019 0.0075 0.02
Trichomonas vaginalis pyruvate kinase, putative 0.0039 0.0279 0.1465
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0196 0.1902 1
Onchocerca volvulus 0.0017 0.0058 0.0606
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0549 0.2743
Echinococcus multilocularis chromobox protein 1 0.015 0.1423 0.1408
Schistosoma mansoni hypothetical protein 0.0101 0.0919 0.1207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0049 0.0259
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0063 0.0527 0.1062
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0519 0.2727
Onchocerca volvulus 0.0015 0.0038 0.04
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0241 0.109
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0412 0.083
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0074 0.064 0.0841
Toxoplasma gondii ABC1 family protein 0.0081 0.0719 0.3653
Trypanosoma brucei ISWI complex protein 0.0018 0.0064 0.014
Giardia lamblia GTOR 0.0048 0.0379 0.1663
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0081 0.0719 0.1349
Leishmania major hypothetical protein, conserved 0.0081 0.0719 0.3653
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0324 0.0307
Brugia malayi Valyl-tRNA synthetase 0.0025 0.0135 0.0272
Brugia malayi hypothetical protein 0.0494 0.4964 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Onchocerca volvulus 0.0104 0.0954 1
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0027 0.0158 0.014
Plasmodium vivax phosphodiesterase gamma, putative 0.0019 0.0075 0.02
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0412 0.2005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0135 0.071
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0379 0.14
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0519 0.2578
Echinococcus granulosus beta LACTamase domain containing family member 0.0081 0.0719 0.0944
Echinococcus granulosus polycomb protein SCMH1 0.0055 0.0449 0.0589
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Schistosoma mansoni zinc finger protein 0.0018 0.0064 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0549 0.2743
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0279 0.2921
Echinococcus multilocularis protein patched 0.0043 0.0324 0.0307
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0151 0.0793
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0275 0.2707 0.2694
Echinococcus granulosus histone acetyltransferase MYST2 0.0063 0.0527 0.0692
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0379 0.14
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0075 0.02
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0183 0.0779
Loa Loa (eye worm) TAR-binding protein 0.0205 0.1986 0.4001
Echinococcus multilocularis ferritin 0.0019 0.0075 0.0057
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0051 0.0412 0.2005
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0118 0.0426
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Leishmania major cathepsin L-like protease 0.0017 0.0058 0.0105
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0866 0.1137
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.01 0.0332
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0025 0.0135 0.052
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0412 0.2005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0205 0.1078
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0165 0.0332
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0019 0.0075 0.02
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0241 0.109
Brugia malayi beta-lactamase family protein 0.0081 0.0719 0.1448
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0332 0.3296 0.4328
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0058 0.0304
Leishmania major phosphoglycerate kinase B, cytosolic 0.0196 0.1902 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0549 0.2743
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0058 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0135 0.071
Onchocerca volvulus 0.0015 0.0038 0.04
Trypanosoma brucei pyruvate kinase 1 0.0039 0.0279 0.129
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0183 0.0779
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0058 0.0105
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0519 0.1045
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0019 0.0075 0.0099
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0412 0.2005
Trichomonas vaginalis D-aminoacylase, putative 0.0081 0.0719 0.378
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0591 0.0574
Onchocerca volvulus 0.0027 0.0165 0.1726
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Echinococcus multilocularis Chromo domain 0.0025 0.0135 0.0118
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0074 0.064 0.0624
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0257 0.0461
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0058 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0058 0.0304
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0549 0.2743
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0049 0.006
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Loa Loa (eye worm) hypothetical protein 0.0051 0.0412 0.083
Brugia malayi chromobox protein homolog 3 0.0084 0.0746 0.1504
Loa Loa (eye worm) hypothetical protein 0.0025 0.0135 0.0272
Onchocerca volvulus 0.0027 0.0165 0.1726
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Echinococcus granulosus Chromobox protein 3 0.0025 0.0135 0.0177
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0275 0.2707 0.3555
Brugia malayi Phosphoglycerate kinase 0.0072 0.0624 0.1257
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0019 0.0075 0.0058
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.002 0.0085 0.0068
Plasmodium vivax acyl-CoA synthetase, putative 0.0038 0.0278 0.1287
Brugia malayi CHD4 protein 0.0027 0.0158 0.0318
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0252 0.1325
Brugia malayi Death domain containing protein 0.0032 0.0213 0.043
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.01 0.0527
Echinococcus granulosus pyruvate kinase 0.0039 0.0279 0.0366
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0019 0.0075 0.0099
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0519 0.2578
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0135 0.071
Loa Loa (eye worm) hypothetical protein 0.002 0.0085 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0075 0.0397
Entamoeba histolytica hypothetical protein 0.0275 0.2707 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0179 0.0943
Loa Loa (eye worm) hypothetical protein 0.0084 0.0746 0.1504
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0866 0.1744
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0176 0.0928
Loa Loa (eye worm) hypothetical protein 0.0027 0.0159 0.032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0412 0.083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0151 0.0793
Mycobacterium ulcerans aldehyde dehydrogenase 0.0074 0.064 0.3232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0179 0.0943
Schistosoma mansoni ferritin light chain 0.0019 0.0075 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0135 0.071
Brugia malayi Cathepsin L-like precursor 0.0017 0.0058 0.0116
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0135 0.0177
Loa Loa (eye worm) hypothetical protein 0.0019 0.0075 0.0152
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0019 0.0075 0.0099
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0196 0.1902 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0412 0.2005
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0519 0.0681
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0032 0.0213 0.028
Loa Loa (eye worm) ctsf protein 0.0017 0.0058 0.0116
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0051 0.0412 0.2005
Loa Loa (eye worm) hypothetical protein 0.0081 0.0719 0.1448
Plasmodium falciparum heterochromatin protein 1 0.0025 0.0135 0.052
Schistosoma mansoni hypothetical protein 0.0018 0.0064 0.0085
Brugia malayi Uncoordinated protein 44 0.0032 0.0213 0.043
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0412 0.1521
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0086 0.077 0.1011
Loa Loa (eye worm) PDE1B protein 0.0019 0.0075 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0135 0.071
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0084 0.0746 0.7826
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0038 0.0041
Echinococcus granulosus tar DNA binding protein 0.0205 0.1986 0.2608
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0075 0.0397
Loa Loa (eye worm) hypothetical protein 0.0051 0.0412 0.083
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0324 0.0653
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0519 0.0681
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0866 0.085
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0086 0.077 0.0754
Schistosoma mansoni tar DNA-binding protein 0.0205 0.1986 0.2608
Schistosoma mansoni tar DNA-binding protein 0.0205 0.1986 0.2608
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0324 0.0426
Schistosoma mansoni hypothetical protein 0.0051 0.0412 0.0541
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0379 0.1829
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.1353 0.1337
Loa Loa (eye worm) hypothetical protein 0.0032 0.0213 0.043
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0183 0.0779
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0746 0.3925
Toxoplasma gondii pyruvate kinase PyK1 0.0039 0.0279 0.129
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0081 0.0719 0.1448
Loa Loa (eye worm) hypothetical protein 0.0163 0.1555 0.3133
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0019 0.0075 0.02
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0038 0.0201
Schistosoma mansoni aldehyde dehydrogenase 0.0074 0.064 0.0841
Onchocerca volvulus 0.0081 0.0719 0.7537
Mycobacterium tuberculosis Conserved protein 0.0081 0.0719 0.1349
Loa Loa (eye worm) hypothetical protein 0.0038 0.0278 0.056
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0051 0.0412 0.083
Brugia malayi Cathepsin L-like precursor 0.0017 0.0058 0.0116
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0412 0.0759
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.01 0.0332
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0072 0.0624 0.3143
Schistosoma mansoni ferritin 0.0019 0.0075 0.0098
Trichomonas vaginalis penicillin-binding protein, putative 0.0081 0.0719 0.378
Toxoplasma gondii cathepsin CPL 0.0017 0.0058 0.0105
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.0549 0.2743
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0019 0.0075 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0278 0.146
Loa Loa (eye worm) hepatopoietin HPO2 0.0035 0.0241 0.0486
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0019 0.0075 0.0099
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0038 0.0041
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0034 0.0068
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0549 0.2743
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.01 0.0527
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.0085 0.0112
Brugia malayi RNA binding protein 0.0205 0.1986 0.4001
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0072 0.0624 0.3143
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0055 0.0449 0.0589
Mycobacterium leprae conserved hypothetical protein 0.0081 0.0719 0.3653
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0038 0.0077
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0038 0.0041
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0019 0.0075 0.0152
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0379 0.1829
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0019 0.0075 0.0152
Schistosoma mansoni cellular tumor antigen P53 0.0104 0.0954 0.1252
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0866 0.085
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0051 0.0412 0.0541
Schistosoma mansoni ankyrin 23/unc44 0.0032 0.0213 0.028
Brugia malayi hypothetical protein 0.0029 0.0183 0.0369
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.01 0.0332
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0519 0.2578
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0081 0.0719 0.1349
Mycobacterium ulcerans bacterioferritin BfrA 0.0019 0.0075 0.0195
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0019 0.0075 0.02
Chlamydia trachomatis pyruvate kinase 0.0039 0.0279 0.0003
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0165 0.0332
Loa Loa (eye worm) hypothetical protein 0.0081 0.0719 0.1448
Loa Loa (eye worm) pyruvate kinase-PB 0.0027 0.0159 0.032
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0176 0.0928
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0719 0.3653
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0038 0.0077
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0019 0.0075 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0151 0.0793
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0019 0.0075 0.0099
Echinococcus multilocularis beta LACTamase domain containing family member 0.0081 0.0719 0.0702
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0019 0.0075 0.02
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0911 0.3366
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.015 0.0791
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0379 0.1994
Loa Loa (eye worm) hypothetical protein 0.0015 0.0038 0.0077
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0241 0.109
Echinococcus multilocularis lamin 0.0027 0.0165 0.0147
Brugia malayi MAP kinase sur-1 0.0062 0.0519 0.1045
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0058 0.0304
Brugia malayi Protein kinase domain containing protein 0.0033 0.0219 0.0441
Loa Loa (eye worm) hypothetical protein 0.0039 0.0279 0.0561
Treponema pallidum phosphoglycerate kinase 0.0196 0.1902 1
Mycobacterium tuberculosis Probable lipase LipE 0.0081 0.0719 0.1349
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0519 0.2727
Schistosoma mansoni tar DNA-binding protein 0.0205 0.1986 0.2608
Schistosoma mansoni apoferritin-2 0.0019 0.0075 0.0098
Schistosoma mansoni pyruvate kinase 0.002 0.0086 0.0113
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0279 0.2921
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0135 0.071
Echinococcus multilocularis tumor protein p63 0.0712 0.7199 0.7194
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.01 0.0332
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0135 0.071
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.002 0.0085 0.0112
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0075 0.02
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0025 0.0135 0.052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0049 0.0259
Brugia malayi RNA recognition motif domain containing protein 0.0205 0.1986 0.4001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0278 0.056
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0019 0.0075 0.0099
Trypanosoma brucei phosphoglycerate kinase 0.0196 0.1902 1
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0019 0.0075 0.0099
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0183 0.0779
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0019 0.0075 0.0099
Echinococcus granulosus GPCR family 2 0.0051 0.0412 0.0541
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.01 0.0332
Brugia malayi Pyruvate kinase, M2 isozyme 0.0039 0.0279 0.0561
Plasmodium falciparum phosphoglycerate kinase 0.0196 0.1902 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0049 0.006
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0135 0.052
Schistosoma mansoni patched 1 0.0043 0.0324 0.0426
Mycobacterium ulcerans esterase/lipase LipP 0.0081 0.0719 0.3653
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0135 0.0177
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0025 0.0135 0.0177
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0019 0.0075 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0307 0.1612
Brugia malayi mbt repeat family protein 0.0055 0.0449 0.0904
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0241 0.109
Chlamydia trachomatis phosphoglycerate kinase 0.0196 0.1902 1
Loa Loa (eye worm) hypothetical protein 0.0494 0.4964 1
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0038 0.0201
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0519 0.2727
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0027 0.0158 0.0207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0278 0.146
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0012 0.0003 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0379 0.1994
Loa Loa (eye worm) hypothetical protein 0.0027 0.0165 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0135 0.071
Brugia malayi Protein cec-1. 0.0025 0.0135 0.0272
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0196 0.1902 1
Echinococcus granulosus lamin 0.0027 0.0165 0.0216
Loa Loa (eye worm) hypothetical protein 0.0038 0.0278 0.056
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0135 0.071
Echinococcus granulosus intermediate filament protein 0.0027 0.0165 0.0216
Echinococcus multilocularis cysteine protease 0.0017 0.0058 0.004
Entamoeba histolytica hypothetical protein 0.0275 0.2707 1
Mycobacterium tuberculosis Probable esterase LipL 0.0081 0.0719 0.1349
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0038 0.0077
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0278 0.1287
Loa Loa (eye worm) hypothetical protein 0.0025 0.0135 0.0272
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0135 0.071
Onchocerca volvulus 0.0025 0.0135 0.1416
Trichomonas vaginalis pyruvate kinase, putative 0.0039 0.0279 0.1465
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0519 0.2578
Echinococcus granulosus cathepsin l1 0.0017 0.0058 0.0076
Mycobacterium tuberculosis Probable hydrolase 0.0081 0.0719 0.1349
Leishmania major cathepsin L-like protease 0.0017 0.0058 0.0105
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0038 0.0041
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.0085 0.0068
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0058 0.0076
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0019 0.0075 0.0058
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.02
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.01 0.0332
Loa Loa (eye worm) hypothetical protein 0.0081 0.0719 0.1448
Loa Loa (eye worm) hypothetical protein 0.0049 0.0389 0.0783
Schistosoma mansoni ferritin 0.0019 0.0075 0.0098
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.02
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0165 0.0332
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.015 0.0197
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.01 0.016
Loa Loa (eye worm) hypothetical protein 0.0081 0.0719 0.1448
Brugia malayi TAR-binding protein 0.0205 0.1986 0.4001
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0049 0.0065
Echinococcus multilocularis zinc finger protein 0.0023 0.0115 0.0098
Onchocerca volvulus 0.0015 0.0038 0.04
Leishmania major cathepsin L-like protease 0.0065 0.0549 0.2743
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0412 0.2005
Echinococcus multilocularis tar DNA binding protein 0.0205 0.1986 0.1972
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0279 0.0561
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.0309 0.0292
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.015 0.0197
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Onchocerca volvulus Heterochromatin protein 1 homolog 0.009 0.0812 0.8513
Schistosoma mansoni ferritin 0.0019 0.0075 0.0098
Entamoeba histolytica hypothetical protein 0.0025 0.0135 0.0499
Leishmania major pyruvate kinase 0.0039 0.0279 0.129
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0379 0.0362
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0183 0.0779
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.0309 0.0406
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Schistosoma mansoni hypothetical protein 0.0051 0.0412 0.0541
Schistosoma mansoni hypothetical protein 0.0125 0.1167 0.1533
Echinococcus granulosus chromobox protein 1 0.015 0.1423 0.1869
Loa Loa (eye worm) hypothetical protein 0.0025 0.0135 0.0272
Brugia malayi Bromodomain containing protein 0.0044 0.0337 0.0679
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0135 0.0499
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0019 0.0075 0.0397
Leishmania major hypothetical protein, conserved 0.0029 0.0183 0.0779
Schistosoma mansoni pyruvate kinase 0.0039 0.0279 0.0366
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0519 0.2578
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0025 0.0135 0.0177
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0196 0.1902 1
Leishmania major cathepsin L-like protease 0.0017 0.0058 0.0105
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0019 0.0075 0.02
Echinococcus multilocularis Chromobox protein 3 0.0025 0.0135 0.0118
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0038 0.0077
Onchocerca volvulus 0.0066 0.056 0.587
Loa Loa (eye worm) helicase 0.0025 0.0135 0.0272
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0081 0.0719 0.0944
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Echinococcus granulosus expressed conserved protein 0.0094 0.0849 0.1115
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0072 0.0624 0.3143
Echinococcus granulosus ferritin 0.0019 0.0075 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0016 0.0084
Trichomonas vaginalis esterase, putative 0.0081 0.0719 0.378
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0019 0.0075 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0216 0.1135
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0068 0.0578 0.0561
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0332 0.3296 0.3284
Entamoeba histolytica hypothetical protein 0.0025 0.0135 0.0499
Entamoeba histolytica hypothetical protein 0.0275 0.2707 1
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0058 0.0214
Onchocerca volvulus Netrin receptor homolog 0.0032 0.0213 0.2237
Brugia malayi CHE-14 protein 0.0043 0.0324 0.0653
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.01 0.014
Leishmania major hypothetical protein, conserved 0.0035 0.0241 0.109
Loa Loa (eye worm) hypothetical protein 0.0015 0.0038 0.0077
Loa Loa (eye worm) hypothetical protein 0.01 0.0911 0.1836
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0019 0.0075 0.02
Echinococcus multilocularis cysteine protease 0.0017 0.0058 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.015 0.0791
Brugia malayi Calcitonin receptor-like protein seb-1 0.0163 0.1555 0.3133
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0519 0.2578
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0018 0.0023
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0038 0.0021
Echinococcus multilocularis pyruvate kinase 0.002 0.0086 0.0068
Mycobacterium tuberculosis Probable lipase LipD 0.0081 0.0719 0.1349
Plasmodium vivax phosphoglycerate kinase, putative 0.0196 0.1902 1
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0135 0.071
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0278 0.1287
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0038 0.005
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Loa Loa (eye worm) beta-lactamase 0.0081 0.0719 0.1448
Entamoeba histolytica hypothetical protein 0.0275 0.2707 1
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0075 0.02
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0412 0.083
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Schistosoma mansoni hypothetical protein 0.0041 0.0308 0.0405
Giardia lamblia Pyruvate kinase 0.002 0.0086 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0058 0.0304
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0519 0.2427
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.1201 0.242
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0019 0.0075 0.0058
Loa Loa (eye worm) hypothetical protein 0.0038 0.0278 0.056
Brugia malayi Cathepsin L-like precursor 0.0017 0.0058 0.0116
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0019 0.0075 0.02
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0058 0.0076
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0379 0.0764
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0063 0.0527 0.0692
Onchocerca volvulus 0.0025 0.0135 0.1416
Echinococcus multilocularis pyruvate kinase 0.0039 0.0279 0.0261
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0135 0.071
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0519 0.2578
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0025 0.0135 0.0272
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0038 0.0041
Brugia malayi mbt repeat family protein 0.0055 0.0449 0.0904
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0038 0.005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0866 0.1137
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Trypanosoma brucei RNA helicase, putative 0.0125 0.1167 0.606
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0035 0.0241 0.0317
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0051 0.0412 0.0395
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0019 0.0075 0.02
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0135 0.071
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0911 0.1197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0549 0.2743
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.002 0.0085 0.0112
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0086 0.077 0.3804
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0049 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0549 0.2743
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0015 0.0038 0.0141
Schistosoma mansoni hypothetical protein 0.0024 0.0128 0.0168
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0719 0.3653
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0196 0.1902 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0019 0.0075 0.02
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0032 0.0213 0.0196
Loa Loa (eye worm) hypothetical protein 0.0051 0.0412 0.083
Loa Loa (eye worm) heterochromatin protein 1 0.015 0.1423 0.2867
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0135 0.052
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0135 0.0177
Loa Loa (eye worm) hypothetical protein 0.0086 0.077 0.1551
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Trichomonas vaginalis ferritin, putative 0.0019 0.0075 0.0392
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0257 0.0461
Echinococcus granulosus survival motor neuron protein 1 0.0494 0.4964 0.6518
Loa Loa (eye worm) hypothetical protein 0.0025 0.0135 0.0272
Echinococcus multilocularis pyruvate kinase 0.0039 0.0279 0.0261
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0163 0.1555 0.3133
Loa Loa (eye worm) hypothetical protein 0.0025 0.0136 0.0275
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0058 0.0304
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Leishmania major hypothetical protein, conserved 0.0018 0.0064 0.014
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0279 0.2921
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0038 0.0041
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0038 0.0077
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0412 0.2005
Echinococcus granulosus death domain containing protein 0.0032 0.0213 0.028
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Loa Loa (eye worm) hypothetical protein 0.0019 0.0075 0.0152
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0407 0.1978
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0074 0.064 0.3232
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0019 0.0075 0.0152
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0058 0.0116
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0019 0.0075 0.0152
Echinococcus multilocularis pyruvate kinase 0.003 0.0195 0.0178
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0591 0.0776
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0278 0.146
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0135 0.052
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0058 0.0076
Leishmania major cathepsin L-like protease 0.0065 0.0549 0.2743
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0058 0.0606
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0257 0.0461
Leishmania major cathepsin L-like protease 0.0017 0.0058 0.0105
Onchocerca volvulus 0.0017 0.0058 0.0606
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0051 0.0412 0.0759
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.01 0.0202
Echinococcus granulosus chromobox protein 2 0.0025 0.0135 0.0177
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Schistosoma mansoni hypothetical protein 0.0025 0.0135 0.0177
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0058 0.004
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0278 0.1287
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0135 0.071
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0019 0.0075 0.0195
Loa Loa (eye worm) hypothetical protein 0.0017 0.0058 0.0116
Schistosoma mansoni hypothetical protein 0.0041 0.0308 0.0405
Echinococcus multilocularis chromobox protein 1 0.015 0.1423 0.1408
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0051 0.0412 0.2005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0252 0.1325
Onchocerca volvulus 0.0025 0.0135 0.1416
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0086 0.077 0.1011
Brugia malayi hypothetical protein 0.0275 0.2707 0.5454
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0075 0.02
Onchocerca volvulus 0.0017 0.0058 0.0606
Trypanosoma cruzi ISWI complex protein 0.0018 0.0064 0.014
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0072 0.0624 0.3143
Schistosoma mansoni microtubule-associated protein tau 0.0752 0.7616 1
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0038 0.0041
Schistosoma mansoni lamin 0.0027 0.0165 0.0216
Loa Loa (eye worm) hypothetical protein 0.0111 0.1026 0.2067
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0068 0.0578 0.0758
Loa Loa (eye worm) hypothetical protein 0.0025 0.0135 0.0272
Loa Loa (eye worm) hypothetical protein 0.0038 0.0278 0.056
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.01 0.0083
Loa Loa (eye worm) hypothetical protein 0.0025 0.0135 0.0272
Giardia lamblia Pyruvate kinase 0.0039 0.0279 0.1112
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0183 0.0779
Echinococcus granulosus expressed protein 0.0019 0.0075 0.0098
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0241 0.109
Brugia malayi Augmenter of liver regeneration 0.0035 0.0241 0.0486
Schistosoma mansoni pyruvate kinase 0.0039 0.0279 0.0366
Schistosoma mansoni hypothetical protein 0.0275 0.2707 0.3555
Brugia malayi Cathepsin L-like precursor 0.0017 0.0058 0.0116
Echinococcus granulosus chromobox protein 1 0.015 0.1423 0.1869
Schistosoma mansoni hypothetical protein 0.0041 0.0308 0.0405
Leishmania major hypothetical protein, conserved 0.0019 0.0075 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0163 0.1555 0.3133
Plasmodium vivax pyruvate kinase, putative 0.0039 0.0279 0.129
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0196 0.1902 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0075 0.0152
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0135 0.071
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0049 0.0065
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0519 0.0502
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0085 0.0112
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0058 0.0105
Loa Loa (eye worm) hypothetical protein 0.0043 0.0324 0.0653
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Plasmodium vivax vivapain-2 0.0017 0.0058 0.0105
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0213 0.043
Schistosoma mansoni lamin 0.0027 0.0165 0.0216
Schistosoma mansoni tar DNA-binding protein 0.0205 0.1986 0.2608
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0866 0.1137
Toxoplasma gondii pyruvate kinase PyKII 0.002 0.0086 0.0257
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0019 0.0075 0.0397
Brugia malayi Bromodomain containing protein 0.0087 0.0773 0.1556
Echinococcus multilocularis expressed protein 0.0019 0.0075 0.0057
Echinococcus multilocularis GPCR, family 2 0.0051 0.0412 0.0395
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0252 0.1147
Trichomonas vaginalis chromobox protein, putative 0.009 0.0812 0.427
Echinococcus granulosus microtubule associated protein 2 0.0752 0.7616 1
Trypanosoma brucei phosphoglycerate kinase 0.0072 0.0624 0.3143
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0519 0.0502
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0379 0.1829
Echinococcus multilocularis chromobox protein 2 0.0025 0.0135 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0519 0.0681
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0019 0.0075 0.0397
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0379 0.0764
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0025 0.0135 0.0118
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0412 0.1521
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Mycobacterium ulcerans aldehyde dehydrogenase 0.0074 0.064 0.3232
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0412 0.2005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0519 0.2727
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0051 0.0412 0.2005
Mycobacterium leprae Probable lipase LipE 0.0081 0.0719 0.3653
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0019 0.0075 0.0152
Echinococcus multilocularis expressed conserved protein 0.0094 0.0849 0.0833
Plasmodium vivax heterochromatin protein 1, putative 0.0025 0.0135 0.052
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0019 0.0075 0.02
Loa Loa (eye worm) hypothetical protein 0.0081 0.0719 0.1448
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0205 0.1986 0.4001
Brugia malayi PHD-finger family protein 0.0029 0.0178 0.0359
Onchocerca volvulus 0.0055 0.0449 0.4704
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0038 0.0041
Leishmania major cathepsin L-like protease 0.0065 0.0549 0.2743
Trypanosoma brucei protein kinase, putative 0.0062 0.0519 0.2578
Schistosoma mansoni tar DNA-binding protein 0.0205 0.1986 0.2608
Plasmodium falciparum acyl-CoA synthetase 0.0038 0.0278 0.1287
Echinococcus granulosus lamin dm0 0.0027 0.0165 0.0216
Loa Loa (eye worm) hypothetical protein 0.0027 0.0159 0.0321
Plasmodium vivax hypothetical protein, conserved 0.0081 0.0719 0.3653
Trichomonas vaginalis D-aminoacylase, putative 0.0081 0.0719 0.378
Leishmania major hypothetical protein, conserved 0.0019 0.0075 0.02
Trichomonas vaginalis chromobox protein, putative 0.015 0.1423 0.7485
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0038 0.0278 0.1287
Leishmania major pyruvate kinase 0.0039 0.0279 0.129
Echinococcus granulosus zinc finger protein 0.0023 0.0115 0.0151
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0866 0.1137
Schistosoma mansoni hypothetical protein 0.0032 0.0213 0.028
Schistosoma mansoni hypothetical protein 0.0013 0.0018 0.0023
Loa Loa (eye worm) STAT protein 0.0134 0.1257 0.2532
Trypanosoma brucei phosphoglycerate kinase 0.0196 0.1902 1
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.1353 0.1776
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0449 0.0589
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0086 0.077 0.0754
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0019 0.0075 0.0099
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0058 0.0214
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0058 0.0304
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0257 0.0461
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0549 0.2743
Trichomonas vaginalis Heterochromatin protein, putative 0.0025 0.0135 0.071
Schistosoma mansoni ap endonuclease 0.0021 0.01 0.0131
Brugia malayi Cathepsin L-like precursor 0.0017 0.0058 0.0116
Loa Loa (eye worm) hypothetical protein 0.0104 0.0954 0.1921
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0278 0.146
Schistosoma mansoni ap endonuclease 0.0021 0.01 0.0131
Onchocerca volvulus 0.0081 0.0719 0.7537
Echinococcus multilocularis microtubule associated protein 2 0.0752 0.7616 0.7612
Entamoeba histolytica pyruvate kinase, putative 0.0027 0.0159 0.0587
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0379 0.1829
Onchocerca volvulus 0.0081 0.0719 0.7537
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0027 0.0158 0.0207
Loa Loa (eye worm) CHromoDomain protein family member 0.0027 0.0158 0.0318
Schistosoma mansoni apoferritin-2 0.0019 0.0075 0.0098
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.0278 0.0502
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0135 0.071
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0081 0.0719 0.0944
Schistosoma mansoni hypothetical protein 0.0051 0.0412 0.0541
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0074 0.064 0.1198
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0314 0.3114 0.3102
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0019 0.0075 0.0099
Giardia lamblia Phosphoglycerate kinase 0.0196 0.1902 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Schistosoma mansoni bromodomain containing protein 0.0073 0.0634 0.0832
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0058 0.0606
Mycobacterium tuberculosis Possible penicillin-binding protein 0.052 0.5224 1
Trichomonas vaginalis chromobox protein, putative 0.015 0.1423 0.7485
Echinococcus multilocularis musashi 0.0027 0.0165 0.0147
Mycobacterium tuberculosis Conserved protein 0.0081 0.0719 0.1349
Schistosoma mansoni transcription factor LCR-F1 0.0275 0.2707 0.3555
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0151 0.0793
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0019 0.0075 0.0152
Echinococcus multilocularis Ankyrin 0.0032 0.0215 0.0197
Schistosoma mansoni hypothetical protein 0.0339 0.3366 0.442
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0028
Onchocerca volvulus 0.0017 0.0058 0.0606
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0058 0.0304
Schistosoma mansoni chromobox protein 0.015 0.1423 0.1869
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.02
Mycobacterium ulcerans beta-lactamase 0.0081 0.0719 0.3653
Plasmodium falciparum phosphodiesterase delta, putative 0.0019 0.0075 0.02
Loa Loa (eye worm) hypothetical protein 0.0032 0.0215 0.0432
Trichomonas vaginalis penicillin-binding protein, putative 0.0081 0.0719 0.378
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Loa Loa (eye worm) oxidoreductase 0.0015 0.0038 0.0077
Plasmodium falciparum phosphodiesterase gamma, putative 0.0019 0.0075 0.02
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Onchocerca volvulus 0.0101 0.0919 0.9639
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0075 0.02
Echinococcus granulosus netrin receptor unc 5 0.0032 0.0213 0.028
Schistosoma mansoni hypothetical protein 0.0051 0.0412 0.0541
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.015 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0049 0.0259
Schistosoma mansoni phosphoglycerate kinase 0.0196 0.1902 0.2497
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0379 0.1829
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0034 0.0068
Brugia malayi Heterochromatin protein 1 0.015 0.1423 0.2867
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0019 0.0075 0.0058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0135 0.071
Mycobacterium leprae Probable pyruvate kinase PykA 0.0039 0.0279 0.129
Brugia malayi MH2 domain containing protein 0.0128 0.1201 0.242
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0081 0.0719 0.1448
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0072 0.0624 0.3143
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0092 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0049 0.0259
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0549 0.2743
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0252 0.1325
Schistosoma mansoni chromobox protein 0.0025 0.0135 0.0177
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0927 0.1218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.015 0.0791
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0051 0.0412 0.0395
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0252 0.1325
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0241 0.109
Schistosoma mansoni hypothetical protein 0.0111 0.1026 0.1347
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0412 0.2005
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0063 0.0527 0.051
Echinococcus granulosus pyruvate kinase 0.002 0.0086 0.0113
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0019 0.0075 0.0152
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0549 0.2743
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0038 0.0041
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0019 0.0075 0.0397
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.1201 0.242
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0058 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0494 0.2599
Brugia malayi Phosphoglycerate kinase 0.0196 0.1902 0.3831
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0279 0.0561
Entamoeba histolytica phosphoglycerate kinase, putative 0.0196 0.1902 0.7024
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0058 0.0076
Loa Loa (eye worm) hypothetical protein 0.0055 0.0449 0.0904
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0049 0.0032
Schistosoma mansoni survival motor neuron protein 0.0101 0.0919 0.1207
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0492 0.2433
Echinococcus granulosus Chromo domain 0.0025 0.0135 0.0177
Echinococcus granulosus Ankyrin 0.0032 0.0215 0.0282
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0135 0.071
Plasmodium vivax vivapain-2 0.0017 0.0058 0.0105
Echinococcus multilocularis pyruvate kinase 0.002 0.0086 0.0068
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0086 0.077 0.3928
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.01 0.014
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0379 0.0498
Mycobacterium ulcerans pyruvate kinase 0.0039 0.0279 0.129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0379 0.1994
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0252 0.1325
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0135 0.071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0549 0.2743
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0183 0.0369
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0068 0.0578 0.1163
Trichomonas vaginalis chromobox protein, putative 0.009 0.0812 0.427
Trypanosoma cruzi ISWI complex protein 0.0018 0.0064 0.014
Leishmania major phosphoglycerate kinase C, glycosomal 0.0196 0.1902 1
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0494 0.2599
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0019 0.0075 0.0099
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0324 0.0426
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0019 0.0075 0.0397
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0038 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0075 0.02
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0058 0.0105
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0221 0.2156 0.2142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0549 0.2743
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0058 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0278 0.146
Toxoplasma gondii exonuclease III APE 0.0021 0.01 0.0332
Schistosoma mansoni chromobox protein 0.0025 0.0135 0.0177
Schistosoma mansoni chromobox protein 0.015 0.1423 0.1869
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0135 0.071
Mycobacterium ulcerans aldehyde dehydrogenase 0.0074 0.064 0.3232
Loa Loa (eye worm) hypothetical protein 0.0047 0.0366 0.0738
Plasmodium falciparum pyruvate kinase 2 0.002 0.0086 0.0257
Brugia malayi STAT protein, DNA binding domain containing protein 0.0134 0.1257 0.2532
Loa Loa (eye worm) cysteine protease 0.0017 0.0058 0.0116
Mycobacterium ulcerans hypothetical protein 0.0081 0.0719 0.3653
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0049 0.0259
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0135 0.0499
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0019 0.0075 0.02
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0068 0.0578 0.1163
Loa Loa (eye worm) latrophilin receptor protein 2 0.0051 0.0412 0.083
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0081 0.0719 0.1349
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0081 0.0719 0.3653
Echinococcus granulosus phosphoglycerate kinase 1 0.0196 0.1902 0.2497
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0089 0.0273
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0019 0.0075 0.0099
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0085 0.0112
Loa Loa (eye worm) mbt repeat family protein 0.0055 0.0449 0.0904
Echinococcus multilocularis survival motor neuron protein 1 0.0494 0.4964 0.4955
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0032 0.0213 0.043
Loa Loa (eye worm) hypothetical protein 0.0066 0.056 0.1128
Loa Loa (eye worm) fibroinase 0.0017 0.0058 0.0116
Loa Loa (eye worm) hypothetical protein 0.0053 0.0424 0.0853
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0032 0.0215 0.0282
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0252 0.1325
Brugia malayi latrophilin 2 splice variant baaae 0.0111 0.1026 0.2067
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0019 0.0025
Echinococcus multilocularis lamin dm0 0.0027 0.0165 0.0147
Trypanosoma cruzi pyruvate kinase 2, putative 0.0039 0.0279 0.129
Mycobacterium ulcerans lipase LipD 0.0081 0.0719 0.3653
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0075 0.02
Plasmodium vivax pyruvate kinase 2, putative 0.002 0.0086 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0179 0.0943
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0101 0.0919 0.1852
Echinococcus granulosus nuclear factor of activated T cells 5 0.0314 0.3114 0.4089

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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