Posted by Stuart Ralph on 2007-08-03 13:27:35
A list of potential Plasmodium protease drug targets.
*NB Relies on the word "protease" or "peptidase" appearing in gene name to identify proteases - maybe also possible with EC numbers?
The weighting is
In Plasmodium, has a name like âpeptidaseâ: 100
In Plasmodium, has a name like âproteaseâ: 100
has literature: 30
has modelled or solved structure: 50
druggability >0.3: 50
no orthologues in mammals: 50
essential in some organism: 30